Podcasts about Epidemiology

An outbreak of the foodborne illness cyclosporiasis has sent thousands of people running to the bathroom this summer. Health officials have linked the outbreak to lettuce served at Taco Bell locations in five states, but there are still a lot of unanswered questions. Food safety expert Byron Chaves joins Flora to talk about the “explosive” nature of the illness and why pinpointing a source of the parasite has been so difficult. Guest: Dr. Byron Chaves is an associate extension specialist and professor in the Department of Food Science at Rutgers University in New Jersey.  Other episodes you may enjoy: How does a tick bite cause a red meat allergy? Use of herbicide linked to Parkinson's is on the rise in the US Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that's keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

We're always looking for ways to stay young, healthy, and beautiful. But the so-called "fountain of youth"... could be in your neighborhood movie theater. So maybe it's actually the "soda fountain of youth?" A new study published this week in the Journal of Epidemiology and Community Health says engaging in cultural experiences like going to the movies or visiting a museum could be linked to slower physiological aging. Greg and Holly discuss and are then joined by the KSL Movie Show hosts Val Cameron and Andy Farnsworth to discuss the big movie of the week: The Odyssey.

Send us Fan MailWe usually think of health ministers as politicians. Dr. Evis Sala, MD, PhD is something entirely different. She's one of the world's leading cancer imaging researchers who helped pioneer AI in radiology - and now she's responsible for the healthcare of an entire nation. What happens when a scientist takes the helm of public health?Our guest today is one of the world's leading physician-scientists in medical imaging who has recently taken on one of the biggest leadership challenges in healthcare.Dr. Evis Sala, MD, PhD ( https://www.kryeministria.al/en/ministrat/evis-sala/ ) currently serves as the Minister of Health and Social Protection of Albania  ( https://shendetesia.gov.al/en/hap/ ). Before entering government, Dr. Sala built an extraordinary international career spanning the University of Cambridge, Memorial Sloan Kettering Cancer Center, Weill Cornell Medicine, and Rome's Policlinico Gemelli, while becoming internationally recognized for her pioneering work in advanced cancer imaging, precision diagnostics, women's cancers, and the integration of artificial intelligence into radiology.Holding both an MD from the University of Tirana and a PhD in Epidemiology from the University of Cambridge, Dr. Sala has spent decades helping shape how we detect, diagnose, and ultimately treat cancer. Today, she is applying that scientific rigor and international experience to improving the health of an entire nation.#EvisSala #Healthcare #PublicHealth #Medicine #ArtificialIntelligence #AI #Radiology #CancerResearch #PrecisionMedicine #CancerImaging #MedicalInnovation #DigitalHealth #HealthPolicy #Oncology #MRI #FutureOfMedicine #HealthcareInnovation #MedicalTechnology #SciencePodcast #ProgressPotentialPossibilitiesSupport the show

In this episode of Mind the Kids, the podcast from the Association for Child and Adolescent Mental Health (ACAMH), host Clara Faria — academic clinical fellow in child psychiatry — is joined by Dr. Karolin Krause, clinical epidemiologist and measurement scientist at the Center for Research in Epidemiology and Statistics (CRESS), Université Paris Cité.Dr. Krause shares findings from her recently published paper in JCPP, the Journal of Child Psychology and Psychiatry. The paper — a scoping umbrella review — systematically maps 80 instruments used to measure life impact in youth mental health research across three interconnected domains: functioning, quality of life, and well-being. Despite major international core outcome set initiatives — including ICHOM and In-ROADS — consistently identifying functioning and quality of life as critical outcomes alongside symptoms, no consensus exists on which instruments to use, and the landscape remains highly fragmented.The rationale runs deeper than methodology. Outcomes measurement in child and adolescent mental health is foundational to evidence-based, person-centred care. Symptom severity and life impact do not always move in step — the DSM-5 itself requires both symptom threshold and clinically significant impairment for diagnosis, yet instruments frequently conflate the two constructs, making it difficult to track which improves first in treatment and whether the gains that matter most to young people are being captured. Across the 80 instruments identified, the review found wide variation in informant type, length, age range, and developmental setting. More than a quarter were classified differently across reviews — a consequence of unclear construct definitions, limited co-production with young people, and what the paper terms "jingle-jangle fallacies." A notable gap emerges for the 19–24 age group navigating the transition from CAMHS to adult services, for whom no instrument has been specifically validated.Clara and Karolin discuss why functioning and life impact deserve dedicated measurement separate from symptom scales, the case for self-report over adult-observer-dominated measures, the trade-offs of multi-informant approaches, and a Wellcome-funded project focused on the development of an evidence synthesis platform for patient-reported outcome measure selection aimed at making evidence-based instrument choice more accessible to researchers worldwide”A must-listen for anyone working in child and adolescent mental health, CAMHS outcomes, youth mental health outcomes measurement, functioning measures, quality of life in children and young people, patient-reported outcome measures, or routine outcome measurement in research and practice.The the JCPP paper 'Research Review: Measuring life impact of youth mental health difficulties: scoping umbrella review of 80 instruments'Karolin R. Krause, Sophie Chung, Christiane Konstantopoulos, Terri Rodak, Ana Calderón, Nichol Edwards Snagg, Kristin Cleverley, Nancy J. Butcher, Giovanni A. Salum, Kathleen R. Merikangas, Peter Szatmari First published: 11 March 2026 https://doi.org/10.1111/jcpp.70134Get a free CPD/CME certificate for listening to this podcast by registering for a FREE ACAMH Learn account at https://bit.ly/4fF4BBWVisit https://www.acamh.orgFacebook and LinkedIn search / ACAMHInstagram https://www.instagram.com/assoc.camhBluesky https://bsky.app/profile/acamh.bsky.socialX https://x.com/acamh

“When we engage in the arts, it exposes us to a lot of emotions, which can have a tangible impact on the neurotransmitters released in our brains, the stress hormones in our bodies, and even the levels of inflammation in our immune system,” says Daisy Fancourt.  Fancourt is a Professor of Psychobiology and Epidemiology at University College London where she heads the Social Biobehavioural Research Group, and serves as the Director of the World Health Organization Collaborating Centre on Arts and Health. She is one of the most highly cited scientists in the world, having published 300 scientific papers and won over two dozen academic prizes. She is a multi-award-winning science communicator and has been named a World Economic Forum Global Shaper and BBC New Generation Thinker.  00:00 - Art as the fifth pillar of health 01:21 - The benefits of arts engagement 08:10 - Your daily & weekly arts prescription 09:35 - Why attention is the key ingredient 11:12 - Visual vs. audio art 14:56 - Making the most of a museum visit 18:11 - Art for stress & mood regulation 19:09 - Using art to wind down 21:04 - Art & the brain 27:44 - Prescribing art for anxiety & depression 32:08 - Reconnecting with childhood creativity 34:14 - Finding art in the every day 36:45 - Biological evidence of art's impact 40:14 - Art for joy & exercise 44:54 - The creative commute Referenced in the episode:  Greece's art program for mental health: https://artonprescription.gr/en/   For more about Fancourt & her research, visit: https://sbbresearch.org/  Buy Fancourt's book here: https://a.co/d/03ypycB7  We hope you enjoy this episode, and feel free to watch the full video on YouTube! Whether it's an article or podcast, we want to know what we can do to help here at mindbodygreen. Let us know at: podcast@mindbodygreen.com. Learn more about your ad choices. Visit megaphone.fm/adchoices

Summer brings an increased risk of tick bites, and this year that risk may be arriving earlier than expected. Alison Hinckley, lead of Epidemiology and Surveillance in CDC's Division of Vector-Borne Diseases, explains what the latest surveillance data show, why emergency department visits for tick bites are rising sooner than usual, and the simple prevention steps health agencies can promote to help reduce tick-borne diseases. Then, Latoya Sahadeo, ASTHO's director of the Developing Executives Leading in Public Health (DELPH) Program, discusses how leadership development goes beyond preparing for the next promotion. She shares how DELPH helps public health professionals strengthen their leadership identity, build resilience through coaching and peer networks, and gain the confidence to lead.DELPH Open HouseApplications | ASTHO

Welcome to the Plant-Based Canada Podcast! In today's episode, we're joined by Dr. Vasanti Malik to discuss sustainable, healthy diets and environmental impacts. Dr. Vasanti Malik is an Associate Professor in the Department of Nutritional Sciences at the University of Toronto and holds a Tier 2 Canada Research Chair in Nutrition and Chronic Disease Prevention. She also serves as an adjunct faculty member at the Harvard T.H. Chan School of Public Health. Dr. Malik earned her MSc in Nutritional Sciences from the University of Toronto and a dual doctorate in Nutrition and Epidemiology from Harvard, where she also completed postdoctoral training.Her research focuses on dietary and lifestyle determinants of obesity and cardiometabolic diseases across diverse populations and life stages, with additional expertise in environmental sustainability and food systems. Using epidemiological studies, clinical trials, and evidence synthesis, she has published more than 150 peer-reviewed papers that have informed dietary guidelines and health policy internationally. Dr. Malik has contributed to expert advisory initiatives with organizations including World Health Organization and American Heart Association, and collaborates on global nutrition and chronic disease prevention research in Canada, the United States, and internationally.WebsiteDr. Vasanti Malik: https://nutrisci.med.utoronto.ca/faculty/vasanti-malikResources:TOsustain: https://utsc.utoronto.ca/foodandfarm/tosustainTMU Urban Farm: https://www.torontomu.ca/sciencerendezvous/activity-booths/urbanfarm/Lancet Planetary Health Abstract: https://pubmed.ncbi.nlm.nih.gov/38632913/ Diabetes & Community Gardens: https://healthypopulationsnetwork.utoronto.ca/news/catalyst-grants-fund-projects-aimed-reducing-type-2-diabetes-risk-peel-region Plant-Based Canada's Socials:Instagram  (@plantbasedcanadaorg)Facebook (Plant-Based Canada, https://m.facebook.com/plantbasedcanadaorg/)Website  (https://www.plantbasedcanada.org/)X / Twitter @PBC_orgBonus PromotionCheck out University of Guelph's online Plant-Based Nutrition Certificate. Each 4-week course will guide you through essential plant-based topics including nutritional benefits, disease prevention, and environmental impacts. You can also customize your learning with unique courses such as Plant-Based Diets for Athletes and Implementing a Plant-Based Diet at Home. As the first university-level plant-based certificate in Canada, you'll explore current research, learn from leading industry experts, and join a community of like-minded people. Use our exclusive discount code PBC2026 to save 10% on all Plant-Based Nutrition Certificate courses. uoguel.ph/pbn.Thank you for tuning in! Make sure to subscribe to the Plant-Based Canada Podcast so you get notified when new episodes are published. This episode was hosted by Stephanie Nishi RD, PhD.Support the show

rWotD Episode 3338: Forensic epidemiology Welcome to random Wiki of the Day, your journey through Wikipedia's vast and varied content, one random article at a time.The random article for Wednesday, 24 June 2026, is Forensic epidemiology.The discipline of forensic epidemiology (FE) is a hybrid of principles and practices common to both forensic medicine and epidemiology. FE is directed at filling the gap between clinical judgment and epidemiologic data for determinations of causality in civil lawsuits and criminal prosecution and defense.Forensic epidemiologists formulate evidence-based probabilistic conclusions about the type and quantity of causal association between an antecedent harmful exposure and an injury or disease outcome in both populations and individuals. The conclusions resulting from an FE analysis can support legal decision-making regarding guilt or innocence in criminal actions, and provide an evidentiary support for findings of causal association in civil actions.Applications of forensic epidemiologic principles are found in a wide variety of types of civil litigation, including cases of medical negligence, toxic or mass tort, pharmaceutical adverse events, medical device and consumer product failures, traffic crash-related injury and death, person identification and life expectancy.This recording reflects the Wikipedia text as of 01:19 UTC on Wednesday, 24 June 2026.For the full current version of the article, see Forensic epidemiology on Wikipedia.This podcast uses content from Wikipedia under the Creative Commons Attribution-ShareAlike License.Visit our archives at wikioftheday.com and subscribe to stay updated on new episodes.Follow us on Mastodon at @wikioftheday@masto.ai.Also check out Curmudgeon's Corner, a current events podcast.Until next time, I'm standard Joey.

Maternity care and its shortcomings will be in the spotlight over the next fortnight, as the biggest maternity inquiry in the history of NHS England prepares to report its findings. The independent review by former midwife, Donna Ockenden, has looked into maternity services at Nottingham University Hospitals NHS Trust. Meanwhile new figures from the Royal College of Midwives show that more than nine out of 10 of those polled felt unsafe staffing levels are directly impacting the quality of care they provide for women and babies. Next week we'll also hear the recommendations of a national review by Baroness Amos. BBC's social affairs correspondent, Michael Buchanan, talks to presenter Nuala McGovern about what we know so far. Joanna Cherry was elected as an MP in 2015, part of the SNP landslide when they took 56 out of 59 Scottish seats, just a year after the referendum on Scottish independence resulted in a No vote. Her memoir, Keeping the Dream Alive, captures the disappointment and euphoria of that time. Joanna went on to lose her seat in 2024 and has become a vocal critic of the party, and of Nicola Sturgeon's leadership. She was also well-known for expressing gender-critical views and concerns at a time when the SNP was trying to deliver a gender self-ID law in Scotland. She joins presenter Nuala McGovern to talk about that "tumultuous decade" in Scottish politics.A new study from the Universities of Exeter and Bristol is looking into how heavy periods impact daily life. Led by Gemma Sharp, a Professor of Epidemiology at Exeter, researchers will collect real-time data from thousands of participants to help us understand the relationship between periods - particularly heavy periods - and our energy levels, sleep and mood. Did you know that mini golf has feminist roots? A playful and ‘playable' exhibition, The Art of Mini Golf, has just opened at the Battersea Arts Centre in London, channelling the inclusive, subversive spirit of the game's female founders. Nuala's joined by curator Grace Herbert and one of the featured artists, Delaine Le Bas, to hear more about mini golf's hidden history and the art it's inspired.Presented by: Nuala McGovern Produced by: Sarah Jane Griffiths

Epidemiology is the study of how and why diseases affect different groups of people, and what the science increasingly shows is that preventing disease and preserving health are deeply connected. In this episode, we focus on endometrial cancer, a disease where many risk factors are within our control. We speak with Immaculata De Vivo, PhD, professor in the Department of Epidemiology at the Harvard T.H. Chan School of Public Health, about how lifestyle factors like movement, nutrition, stress management, and social connection can influence our biology and long-term health. We also explore the biological impact of chronic stress in cancers like endometrial cancer and discuss how listeners can feel more informed, empowered, and proactive during healthcare visits. Credits Host: Neha Pathak, MD, FACP, DipABLM Producer/Editor: Lauren Summers Show Notes: Lauren Summers Guest: Immaculata De Vivo, PhD See omnystudio.com/listener for privacy information.

Plant-based diets cut risk for cancer, COVID, and early death—even when adopted later in life. The science is clear: food is powerful medicine. #VeganHealth #CancerPrevention #FoodIsMedicine #HealthTalks

BUFFALO, NY — June 18, 2026 — A new #research paper was #published in Volume 18 of Aging on May 26, 2026, titled “Early-life determinants of cardiometabolic outcomes and accelerated biological ageing in Colombia.” The study was led by first and corresponding author Juan Carlos Rivillas from the Department of Epidemiology and Biostatistics, MRC Centre for Environment and Health, School of Public Health, Imperial College London, United Kingdom. Experiences during childhood can shape health for decades. Adverse childhood experiences (ACEs), such as emotional abuse, domestic violence, food insecurity, poor health, and forced displacement, have long been linked to chronic disease. However, less is known about how these early-life hardships may influence biological aging itself. In this study, researchers examined whether childhood adversity is associated with cardiometabolic disease and accelerated biological aging among older adults in Colombia. The investigators analyzed data from 3,385 adults aged 60 years and older who participated in the nationally representative SABE-Colombia study. Five forms of childhood adversity experienced before age 15 were evaluated: emotional abuse, domestic violence, poor childhood health, food scarcity, and forced migration related to Colombia's armed conflict. Biological aging was estimated using the Klemera-Doubal Method for Biological Age, a biomarker-based measure that compares biological age with chronological age. Full press release - https://aging-us.net/2026/06/18/childhood-adversity-may-leave-lasting-biological-scars-decades-later/ DOI - https://doi.org/10.18632/aging.206384 Corresponding author - Juan Carlos Rivillas - j.rivillas-garcia20@imperial.ac.uk Abstract video - https://www.youtube.com/watch?v=5w6vgFzjcNQ Sign up for free Altmetric alerts about this article - https://aging.altmetric.com/details/email_updates?id=10.18632%2Faging.206384 Keywords - aging, adverse childhood experiences, forced childhood migration, biological ageing, cardiometabolic outcomes, life course epidemiology To learn more about the journal, please visit https://www.Aging-US.com​​ and connect with us on social media at: Bluesky - https://bsky.app/profile/aging-us.bsky.social ResearchGate - https://www.researchgate.net/journal/Aging-1945-4589 X - https://twitter.com/AgingJrnl Facebook - https://www.facebook.com/AgingUS/ Instagram - https://www.instagram.com/agingjrnl/ LinkedIn - https://www.linkedin.com/company/aging/ Reddit - https://www.reddit.com/user/AgingUS/ Pinterest - https://www.pinterest.com/AgingUS/ YouTube - https://www.youtube.com/@Aging-US Spotify - https://open.spotify.com/show/1X4HQQgegjReaf6Mozn6Mc MEDIA@IMPACTJOURNALS.COM

Why do some kids and teens get overly frustrated and bored when it's time to turn off their video games? How to know when game playing has become excessive? What are tips that all families should know for ensuring healthy video game play? In today's episode of The Screenagers Podcast, Dr. Delaney Ruston explores these issues along with a new model of brain biology to help explain irritability and boredom associated with video gaming. We hear from teens along with psychiatrist Dr. Clifford Sussman who specializes in helping young people regain tech balance. We also hear from Andrew Fulton who was in the film, Screenagers, when he was getting treatment at an internet rehab center, and is now working at the same center helping others recover from video game overuse.   Additional Links Andrew in this episode works at the internet recovery center called reStart To learn more about Dr. Clifford Sussman, go to his website. Dr. Sussman et al.,  Internet and Video Game Addictions: Diagnosis, Epidemiology and Neurobiology.   Here are links to some Tech Talk Tuesday articles about video games: Digital Binging, Is it a Problem? Why 3 Hours is Too Much Fake Identities and Real Concerns Watch What Happens When Kids Have No Screen Time Rules ‍ Additional Resources Screenagers Website Bring Screenagers to Your Community

“Confounding, Confounding, Confounding” is like the epidemiologist's version of “Marcia, Marcia, Marcia” from the Brady Bunch. To discuss Chapter 7 of Causal Inference: What If, we welcome Dr. Ashley Naimi. In this chapter, we discuss confounding as a central problem when estimating causal effects from observational data. The chapter emphasizes that confounding is not just an imbalance in covariates across exposure groups, but a causal problem that depends on the underlying structure of how treatment, outcome, and other variables are related. In this episode, Dr. Naimi helps explain concepts related to confounding, exchangeability, and faithfulness. We (try to) talk through confounding-related DAGs and how they are a useful tool to understand confounding bias.  This episode shows why confounding gets so much attention in epidemiology: it is everywhere, often misunderstood, and, like Marcia Brady, it has a way of stealing the spotlight.

I speak with Johnathan Jarecki, undergraduate science student and host of The Signal Podcast, on all things photobiology. We discuss the full solar spectrum and how ultraviolet, visible, blue, red and near-infrared light each affect human physiology, including the POMC pathway, nitric oxide and blood pressure, and the evidence on sunlight, skin cancer and the vitamin D paradox. We also discuss how artificial light at night suppresses melatonin and disrupts the circadian control of DNA repair, cardiovascular health, and metabolism. TIMESTAMPS03:25 Dr. Max Gulhane04:02 Dr. Gulhane's Love for Science and Medicine09:01 What is Light?12:52 Sunlight Broken Down as a Nutrient14:02 Ultraviolet Light: Sunlight Is More Than Vitamin D15:56 POMC21:38 UVA/UVB on Cardiometabolic Health24:40 Big Picture of UV Light28:41 Sunlight, Skin Cancer, Dermatology Messaging, The Vitamin D Paradox35:10 Blue Light, Artificial Light at Night (ALAN), Mechanisms38:50 Sponsor: Daylight Computer40:34 ALAN, Epidemiology, Cancer, Heart Disease45:04 DNA Repair Mechanisms, Circadian Control47:27 Melanopsin (OPN4), Blue Light, UV Susceptibility53:25 Red, Infrared, Photobiomodulation, Metabolism01:00:08 Blue Light, Metabolism, and the Built Environment01:05:19 Photobiology of Atherosclerosis01:10:11 Blue Light on Cardiovascular Function01:12:25 Three M's of Circadian Health01:18:43 Sunlight, Testosterone, and Reproductive BehaviorFull show notes: https://docs.google.com/document/d/15zOnh_l6WOe6237CbQrFPkeoQjUZXIm9Ul4ncQTNXDQ/edit?pli=1&tab=t.0Show sponsors:

The World Health Organization defines health equity as a public health concept describing equity of access to health resources for genetic, socio-environmental, and economic determinants of health, varying according to individuals, families, and social or societal groups. Concerns about data equity have surfaced, which may result in many populations, including those in rural areas with disabilities, experiencing homelessness or living in low and middle-income regions of the world, being underrepresented in health data sets. This can lead to biased findings and suboptimal health outcomes for certain subgroups, which is the focus of this episode of Stats+Stories with guest Bhramar Mukherjee. Dr. Bhramar Mukherjee is the inaugural Senior Associate Dean of Public Health Data Science and Data Equity and the Anna M. R. Lauder Professor of Biostatistics, as well as Professor of Epidemiology and of Statistics and Data Science at Yale University. Among her many honors, she was elected to the US National Academy of Medicine in 2022.

Send us Fan MailIn this episode of MedEvidence, host Dr. Michael Koren speaks with epidemiologist Dr. Hannah Gardener about how everyday exposures may influence long-term health outcomes.Dr. Gardener shares her journey from neuroscience and epidemiology training at Harvard to her current work studying stroke, dementia, and environmental risk factors. She explains how personal life experiences sparked her interest in environmental health and led her to examine how early-life and daily exposures can shape disease risk across the lifespan.The conversation explores her research on diet soda consumption and its surprising associations with vascular outcomes, including stroke, heart disease, and cognitive decline. She breaks down what “prospective cohort studies” really mean and how to interpret findings without overgeneralizing results.The discussion then expands to PFAS, often called “forever chemicals”, which are widely used in consumer products and persist in the environment and human body. Dr. Gardener explains where these chemicals are found, what health effects have been observed in the research, and practical, evidence-based strategies individuals can use to reduce exposure.This episode offers a thoughtful, research-driven look at how environmental factors, diet choices, and chemical exposures intersect with long-term brain and cardiovascular health—and what can realistically be done today to reduce risk.Be a part of advancing science by participating in clinical research.Have a question for Dr. Koren? Email him at askDrKoren@MedEvidence.comListen on SpotifyListen on Apple PodcastsWatch on YouTubeShare with a friend. Rate, Review, and Subscribe to the MedEvidence! podcast to be notified when new episodes are released.Follow us on Social Media:FacebookInstagramX (Formerly Twitter)LinkedInWant to learn more? Checkout our entire library of podcasts, videos, articles and presentations at www.MedEvidence.comMusic: Storyblocks - Corporate InspiredThank you for listening!

Unprocessed red meat and cancer risk remains one of the most debated topics in nutrition science, partly because the evidence is often presented in overly simplistic terms. The key question is not whether to adopt a vague "balanced" position on red meat, but whether the evidence clearly identifies intake levels at which colorectal cancer risk increases and whether controlled human trials support plausible mechanisms for that risk. A second issue is whether claims that fibre, vegetables, or an otherwise "healthy diet" can neutralise high red meat intake are actually supported by the mechanistic evidence, or whether they overstate what dietary context can plausibly offset. In this episode, Danny and Alan examine the evidence base by moving beyond the usual epidemiology-only debate. They discuss why regional intake patterns and dose thresholds matter, then explore controlled human feeding studies showing how higher red meat intake can increase endogenous N-nitroso compound formation, faecal water genotoxicity, and other mechanistic biomarkers linked to colorectal carcinogenesis. Timestamps: [01:11] Defining the exposure and outcome [02:34] Carcinogen labels explained [07:54] Epidemiology and dose thresholds [14:04] Interpreting null findings [19:09] Bingham 1996 nitroso study [25:20] Hughes dose response trial [33:49] Cross 2003 heme iron mechanism [42:55] Fecal water genotoxicity [55:42] Tumor mutational signatures [59:38] What we can conclude now [01:04:10] Practical intake recommendations [01:08:41] Key ideas segment (premium-only) Links: Go to episode page (includes links to studies mentioned) Subscribe to Sigma Nutrition Premium Join the Sigma newsletter for free Enroll in the next cohort of our Applied Nutrition Literacy course

External control arms are becoming increasingly important in drug development, but creating valid comparisons requires more than matching patient populations. In this episode, I speak with Ben Ackerman, Director of Real-World Biostatistics at GSK, about one of the most overlooked challenges in external control arm studies: endpoint bias. We discuss why differences in how outcomes are measured can influence study results, what researchers should consider when designing studies, and how the field is evolving to address these challenges. If you work with real-world evidence, causal inference, or innovative clinical trial designs, this episode offers valuable insights into improving the credibility and transparency of external control arm analyses.

Dr. Max Gulhane (MD) is a practising family medicine physician and health-optimising physician with a passion for root-cause analysis of human chronic disease and longevity. We discuss the full solar spectrum and how ultraviolet, visible, blue, red and near-infrared light each affect human physiology, including the POMC pathway, nitric oxide and blood pressure, and the evidence on sunlight, skin cancer and the vitamin D paradox. We discuss how artificial light at night suppresses melatonin and disrupts the circadian control of DNA repair, cardiovascular health, and metabolism. For those interested in light and circadian health, Dr. Gulhane offers a grounded, mechanism-focused framework for aligning daily light exposure with human biology.Full Show Notes here. Thank you to our sponsorDaylight Computer: daylightcomputer.com (code JONATHANJ for $25 off)Dr. Max GulhaneWebsite: https://www.drmaxgulhane.com/Instagram: https://www.instagram.com/maxgulhanemd/X: https://x.com/MaxGulhaneMDYouTube: https://www.youtube.com/@maxgulhanemd/Recommended lectures:Sunlight & Cancer: Beyond Skin Deep — https://youtu.be/SJGvr6dGOgQArtificial Light & Diabetes: No Food Required — https://youtu.be/vgrFpPusSKUWhat Your Cardiologist Doesn't Know About Sunlight & Heart Health — https://youtu.be/NaeqPHEM-d0Jonathan JareckiInstagram: https://www.instagram.com/jonathanjarecki/X: https://x.com/jonathanjareckiNewsletter: https://jonathanjarecki.substack.com/?utm_campaign=profile_chips00:00 Intro03:25 Dr. Max Gulhane04:02 Dr. Gulhane's Love for Science and Medicine09:01 What is Light?12:52 Sunlight Broken Down as a Nutrient14:02 Ultraviolet Light: Sunlight Is More Than Vitamin D15:56 POMC21:38 UVA/UVB on Cardiometabolic Health24:40 Big Picture of UV Light28:41 Sunlight, Skin Cancer, Dermatology Messaging, The Vitamin D Paradox35:10 Blue Light, Artificial Light at Night (ALAN), Mechanisms38:50 Sponsor: Daylight Computer40:34 ALAN, Epidemiology, Cancer, Heart Disease45:04 DNA Repair Mechanisms, Circadian Control47:27 Melanopsin (OPN4), Blue Light, UV Susceptibility53:25 Red, Infrared, Photobiomodulation, Metabolism01:00:08 Blue Light, Metabolism, and the Built Environment01:05:19 Photobiology of Atherosclerosis01:10:11 Blue Light on Cardiovascular Function01:12:25 Three M's of Circadian Health01:18:43 Sunlight, Testosterone, and Reproductive Behavior01:24:14 Support, YouTube, Spotify & Apple Follow, Reviews & Feedback, Social Media, Substack Newsletter#science #sunlight #circadianrhythm

Welcome to this week's Midlife Minute. Today, I'm focusing on all the questions I received about gallbladder health, including HRT-provoking symptoms, supplements that improve gallbladder health, and evidence-based food interventions. IN THIS EPISODE, YOU WILL LEARN: Why the risk of gallstones and gallbladder inflammation increases during the menopause transition How estrogen and progesterone HRT have different effects on gallbladder functioning The differences in risk between transdermal and oral HRT How the progesterone in HRT can cause gallbladder issues in some women What TUDCA is, and how it supports gallbladder health The value of TUDCA for women who have had their gallbladders removed How various nutrients and supplements support bile flow and gallbladder health What can contribute to gallstone formation Connect with Cynthia Thurlow   Follow on X, Instagram & LinkedIn Check out Cynthia's website. Submit your questions to support@cynthiathurlow.com  Join other like-minded women in a supportive, nurturing community: The Midlife Pause/Cynthia Thurlow.  Purchase Cynthia's book, The Menopause Gut. Cynthia's Intermittent Fasting Transformation Book The Midlife Pause Supplement Line Gallbladder Research: Cabrera D, Arab JP, Arrese M. UDCA, NorUDCA, and TUDCA in liver diseases: a review of their mechanisms of action and clinical applications. Seminars in Liver Disease. 2019;39(4):397–404. doi:10.1055/s-0039-1696799  Vang S, Longley K, Steer CJ, Low WC. The unexpected uses of urso- and tauroursodeoxycholic acid in the treatment of non-liver diseases. Global Advances in Health and Medicine. 2014;3(3):58–69. doi:10.7453/gahmj.2014.017  Bai M, Yang L, Liao H, et al. Tauroursodeoxycholic acid improves nonalcoholic fatty liver disease by regulating gut microbiota and bile acid metabolism. Journal of Agricultural and Food Chemistry. 2024;72(41):22655–22668. doi:10.1021/acs.jafc.4c04630  Simon JA, Hudes ES. Relation of serum ascorbic acid to serum vitamin B12, serum ferritin, and kidney stones in US adults. *Archives of Internal Medicine.*1999;159(6):619–624. doi:10.1001/archinte.159.6.619  Walcher T, Haenle MM, Kron M, et al. Vitamin C supplement use may protect against gallstones: an observational study on a randomly selected population. BMC Gastroenterology. 2009;9:74. doi:10.1186/1471-230X-9-74  Tsai CJ, Leitzmann MF, Willett WC, Giovannucci EL. Long-term intake of dietary fiber and decreased risk of cholecystectomy in women. American Journal of Gastroenterology. 2004;99(7):1364–1370. doi:10.1111/j.1572-0241.2004.30281.x  Leitzmann MF, Stampfer MJ, Willett WC, Spiegelman D, Colditz GA, Giovannucci EL. Coffee intake is associated with lower risk of symptomatic gallstone disease in women. Gastroenterology. 2002;123(6):1823–1830. doi:10.1053/gast.2002.37085  Moerman CJ, Smeets FW, Kromhout D. Dietary risk factors for clinically diagnosed gallstones in middle-aged men — a 25-year follow-up study. Annals of Epidemiology. 1994;4(3):248–254. doi:10.1016/1047-2797(94)90099-x Association between dietary magnesium intake and gallstones: the mediating role of atherogenic index of plasma. Lipids in Health and Disease. 2024;23(1):82. doi:10.1186/s12944-024-02074-4  Pitt HA, Doty JE, Murphy MM, Schwarz MB. Progesterone alters biliary flow dynamics. Annals of Surgery. 1999;229(2):205–209. doi:10.1097/00000658-199902000-00008

Katherine MacGilchrist comes from a long line of doctors, has degrees in Pharmacology and Epidemiology and spent many years working in the pharmaceuticals industry. But during ‘Covid' she began questioning the narrative and became a pariah and an outcaste. Since then she has found God, started homesteading and now gives talks to her Somerset community on vaccine dangers and how to deal with them. Her Twitter is @unveildeception ↓ ↓ ↓ ↓ Monetary Metals is providing a true alternative to saving and earning in dollars by making it possible to save AND EARN in gold and silver. Monetary Metals has been paying interest on gold and silver for over 8 years. Right now, accredited investors can earn 12% annual interest on silver, paid in silver in their latest silver bond offering. For example, if you have 1,000 ounces of silver in the deal, you receive 120 ounces of silver interest paid to your account in the first year. Go to the link in the description or head to https://monetary-metals.com/delingpole/ to learn more about how to participate and start earning a return on honest money again with Monetary Metals. ↓ ↓ How environmentalists are killing the planet, destroying the economy and stealing your children's future. In Watermelons, an updated edition of his ground-breaking 2011 book, JD tells the shocking true story of how a handful of political activists, green campaigners, voodoo scientists and psychopathic billionaires teamed up to invent a fake crisis called ‘global warming'. This updated edition includes two new chapters which, like a geo-engineered flood, pour cold water on some of the original's sunny optimism and provide new insights into the diabolical nature of the climate alarmists' sinister master plan. Purchase Watermelons by James Delingpole here: https://jamesdelingpole.co.uk/Shop/ ↓ ↓ ↓ Buy James a Coffee at: https://www.buymeacoffee.com/jamesdelingpole To support independent, no-holds-barred journalism and gain first and full access to all James's content, subscribe directly at https://jamesdelingpole.co.uk x

Mace and Jeff put Matt Walsh's antidepressant episode under the clinical microscope — and it does not pass the functional impairment test. They break down the 2022 Molecular Psychiatry umbrella review that dismantled the low-serotonin narrative, explain why that finding doesn't indict SSRIs as a category, and make the case that the “chemical imbalance” pitch was always more pharmaceutical advertising than clinical science. They also tackle what functional impairment actually means in diagnosis, the gender disparity in antidepressant prescribing, whether the SSRI-to-mass-violence argument is causal or just really committed to showing up in the same sentence, and what clinicians should actually be telling clients about medications they can't fully explain. For anyone who has ever explained serotonin to a client and quietly wondered if they knew what they were talking about: this one's for you. Music: “Machine Heart – Instrumental version” by Icarus. Licensed via Artlist Pro License #JeMO9k. Bielefeldt, A. Ø., Danborg, P. B., & Gøtzsche, P. C. (2016). Precursors to suicidality and violence on antidepressants: systematic review of trials in adult healthy volunteers. Journal of the Royal Society of Medicine, 109(10), 381–392. https://doi.org/10.1177/0141076816666805 Brody, D. J., & Gu, Q. (2020). Antidepressant use among adults: United States, 2015–2018. NCHS Data Brief, No. 377. https://www.cdc.gov/nchs/products/databriefs/db377.htm Chua, K. P., Volerman, A., Zhang, J., Hua, J., & Conti, R. M. (2024). Antidepressant dispensing to US adolescents and young adults: 2016–2022. Pediatrics, 153(3), e2023064245. https://doi.org/10.1542/peds.2023-064245 Healy, D., & Mangin, D. (2024). Post-SSRI sexual dysfunction: barriers to quantifying incidence and prevalence. Epidemiology and Psychiatric Sciences, 33, e44. https://doi.org/10.1017/S2045796024000441 Kuehner, C. (2017). Why is depression more common among women than among men? The Lancet Psychiatry, 4(2), 146–158. https://doi.org/10.1016/S2215-0366(16)30263-2 Moncrieff, J., Cooper, R. E., Stockmann, T., Amendola, S., Hengartner, M. P., & Horowitz, M. A. (2023). The serotonin theory of depression: a systematic umbrella review of the evidence. Molecular Psychiatry, 28, 3243–3256. https://doi.org/10.1038/s41380-022-01661-0 Salk, R. H., Hyde, J. S., & Abramson, L. Y. (2017). Gender differences in depression in representative national samples: Meta-analyses of diagnoses and symptoms. Psychological Bulletin, 143(8), 783–822. https://doi.org/10.1037/bul0000102 Stone, M., Laughren, T., Jones, M. L., Levenson, M., Holland, P. C., Hughes, A., Hammad, T. A., Temple, R., & Rochester, G. (2009). Risk of suicidality in clinical trials of antidepressants in adults: analysis of proprietary data submitted to US Food and Drug Administration. BMJ, 339, b2880. https://doi.org/10.1136/bmj.b2880

The benefits of getting a shingles vaccine seem relatively straightforward: It will prevent you from getting shingles, a painful rash caused by the same virus that causes chickenpox. But researchers have found a surprising link between getting the shingles vaccine and a lower risk of developing dementia. And that's not the only vaccine that seems to have additional benefits. So what's going on here?  To help explain this research are epidemiologist Pascal Geldsetzer, who studies the association between the shingles vaccine and lower rates of dementia; and physician and epidemiologist Helen Chu, who studies the Flu, RSV and COVID-19 viruses. Guests: Dr. Pascal Geldsetzer is an assistant professor of medicine, epidemiology and population health at Stanford University.  Dr. Helen Chu is a professor of epidemiology, allergy and infectious diseases at the University of Washington.  Other episodes you may enjoy: Study Finds COVID mRNA Vaccines Boost Cancer Treatment As Cervical Cancer Deaths Plummet, Experts Credit HPV Vaccine Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that's keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Two disease outbreaks are dominating the news: Ebola in the Democratic Republic of the Congo, and hantavirus, which started spreading on a cruise ship. The U.S. has a one-of-a-kind medical facility that exists just for emergencies like this. It's called the National Quarantine Unit, and it's in Omaha, Nebraska. Right now, 18 Americans from the cruise ship where hantavirus broke out are in quarantine there.  Host Flora Lichtman chats with Angie Vasa, a nurse and administrator who has worked at this emergency center for the last 17 years. They discuss how the facility works, what's happening with the travelers exposed to hantavirus, and how they're preparing for the possibility of Ebola-exposed individuals.   Guest: Angie Vasa is the director of emergency preparedness and special pathogens programs at Nebraska Medicine in Omaha, Nebraska.  Other episodes you may enjoy: Mapping Out How Viruses Jump Between Species How Viruses Have Shaped Our World Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that's keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

On episode #107 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 5/7 – 5/20/26. Host: Daniel Griffin and Sarah Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral FDA Grants Accelerated Approval to Gilead's Hepcludex® (bulevirtide-gmod), the First and Only Approved Treatment for Chronic Hepatitis Delta Virus (HDV) (Gileadl) A Phase 3, Randomized Trial ofBulevirtide in Chronic Hepatitis D(NEJM) Study to Assess Efficacy and Safety of Bulevirtide in Participants With Chronic Hepatitis Delta (CHD) (NLM: ClinicalTrials.gov) Andes Hantavirus Outbreak on a Cruise Ship, 2026 (NEJM) Quick takes: Another hantavirus case, polio in 3 countries, NIAID head steps down (CIDRAP) Dolutegravir Reduces Human T-Cell Lymphotropic Virus Type 1 Proviral Load and Improves Neurological Outcomes in a Phase 2 Controlled Trial (CID) Dolutegravir Appears to Lower Human T-Cell Lymphotropic Virus Type 1 (HTLV-1) Proviral Load: The Emerging Rational Approach to Treatment of HTLV-1–Associated Myelopathy (CID) Use of Dolutegravir for treatment of HTLV-1 (CID) Use of dolutegravir to treat people living with HTLV-1-associated myelopathy (HAM) (CID) Bacterial Urinary Tract Infection (UTI)-free and Recurrent UTI (rUTI)-Free Survivals Following Bladder Electrofulguration in Women With a History of Antibiotic-Refractory rUTI (OFID) Azithromycin for Preschoolers with Wheezing in the Emergency Department (JAMA) Rapid Respiratory Microbiological Point-of-Care Testing and Antibiotic Use in Primary Care (JAMA Internal Medicine) Fungal The Last of US Season 2 (YouTube) Changes in Epidemiology of Candidemia in the United States With a Focus on Candida auris (CID) Parasitic Impact of introducing RTS,S/AS01E malaria vaccine on mortality in young children in Ghana, Kenya, and Malawi: an observational evaluation of a cluster-randomised implementation programme (The LANCET) Ivermectin-Benzimidazole Prescribing Following Celebrity Endorsement  (JAMA Network OPEN) Febrile Temperature Augents Ring-stage Plasmodium falciparum Adhesion to Brain Endothelial Cells (JID) An Increase in Imported Plasmodium vivax Malaria in New York City: Clinical and Demographic Trends Following Recent Migration (OFID) Miscellaneous The State of Physician Leadership (WittkKieffer) Infectious Diseases Fellowship Curriculum: IDSA Training Program Directors Community of Practice (TPDCOP), Curricular and Educational REsources Workgroup (CREW) (CID) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.

The majority of non-fatal gunshot wound survivors walk away with a bullet still inside them. Most are discharged without a removal attempt, without a surveillance plan, and without a conversation about what comes next. This episode fills that gap.Dr. Patrick Georgoff is joined by BIG T co-host Dr. Teddy Puzio (UT Houston), gun violence survivor and trauma surgeon Dr. Madhu Subramanian (Duke), and Dr. Tyler Simpson (Duke ACS Fellow) for a practical, honest conversation about one of trauma's most overlooked topics.What we cover: Epidemiology: how common retained fragments really are, and why the downstream burden is underappreciated When to remove (and when not to): a framework for both index hospitalization and delayed removal Forensic evidence: how to handle bullets in the OR without destroying their evidentiary value — and who to call when you don't know Lead toxicity: the rare but real complication that can surface a decade later, which blood lead levels should prompt action, and when to call hematology or toxicology The psychology: retained bullets are independently associated with depression and reduced return to work — and that belongs in the risk-benefit conversation DOMINATE THE DAYBIG T Trauma Full Series: https://behindtheknife.org/podcast-series/big-t-traumaThis episode of Big T Trauma was sponsored by Teleflex, a global provider of medical devices. Learn more at teleflex.com and at the Teleflex Trauma and Emergency Medicine LinkedIn page. Please visit https://behindtheknife.org to access other high-yield surgical education podcasts, videos and more.  If you liked this episode, check out our recent episodes here: https://behindtheknife.org/listenBehind the Knife Premium: https://behindtheknife.org/premiumOral Board Review: https://behindtheknife.org/oral-boardOral Board Simulator: https://behindtheknife.org/oral-board/simulatorGeneral Surgery Oral Board Review Course: https://behindtheknife.org/premium/general-surgery-oral-board-reviewTrauma Surgery Video Atlas: https://behindtheknife.org/premium/trauma-surgery-video-atlasDominate Surgery: A High-Yield Guide to Your Surgery Clerkship: https://behindtheknife.org/premium/dominate-surgery-a-high-yield-guide-to-your-surgery-clerkshipDominate Surgery for APPs: A High-Yield Guide to Your Surgery Rotation: https://behindtheknife.org/premium/dominate-surgery-for-apps-a-high-yield-guide-to-your-surgery-rotationVascular Surgery Oral Board Review Course: https://behindtheknife.org/premium/vascular-surgery-oral-board-reviewColorectal Surgery Oral Board Review Course: https://behindtheknife.org/premium/colorectal-surgery-oral-board-reviewSurgical Oncology Oral Board Review Course: https://behindtheknife.org/premium/surgical-oncology-oral-board-reviewCardiothoracic Oral Board Review Course: https://behindtheknife.org/premium/cardiothoracic-surgery-oral-board-reviewDownload our App:Apple App Store: https://apps.apple.com/us/app/behind-the-knife/id1672420049Android/Google Play: https://play.google.com/store/apps/details?id=com.btk.app&hl=en_US

On today’s “Closer Look with Rose Scott,” we have an in-depth discussion with the Atlanta Legal Aid Society about a study by Princeton University’s Eviction Lab. It shows Fulton, Cobb, DeKalb, Gwinnett, and Clayton Counties lead the nation in evictions. Those evictions overwhelmingly affected Black households -- more than white, Hispanic, and other racial groups combined. We also speak to Dr. Jodie Guest, Professor and Senior Vice Chair in the Department of Epidemiology at Emory University. The Ebola Virus is spreading quickly through central Africa and has already taken hundreds of lives. We learn more about the nature of the deadly illness and what’s being done to stop it from infecting more people.See omnystudio.com/listener for privacy information.

What does it take for a single idea to travel from a research lab in New Haven to war zones in Uganda, refugee camps in Malaysia, and clinics across 30 countries and six continents? In this episode, we sit down with Dr. Myrna Weissman, one of the most consequential figures in modern psychiatry, to find out.Dr. Weissman co-developed Interpersonal Psychotherapy (IPT) alongside her late husband, Dr. Gerald Klerman, on a simple premise: that human suffering is deeply tied to human connection. Grief. Conflict. Loneliness. Life upended. These are not niche clinical categories, but rather a universal language of distress. And IPT was built to respond to it.In this conversation, Dr. Weissman reflects on five decades of research, the pandemic-era project that became a sweeping global volume (now available free via open access), and what it means to build something that outlives its origins. *This episode briefly mentions suicide.(Re-post: This is one of our most beloved episodes, brought back by popular demand. If you've heard it before, we hope it moves you just as much the second time.)What Is Interpersonal Therapy (IPT) and Why Does It Work?IPT links the emergence of psychiatric symptoms to what is happening in a person's current life. It focuses on four core problem areas:1. Grief — the loss of a loved one2. Disputes — conflict with someone important to you3. Transitions — life changes, even positive ones, that disrupt relationships4. Loneliness/Isolation — chronic or newly developed lack of attachmentThese four areas have proven to resonate across vastly different cultures because they reflect fundamental aspects of the human condition. Dr. Weissman emphasizes that IPT is not the only evidence-based psychotherapy — it is “one tool in the toolbox, not a religion.”IPT for AdolescentsAdolescence is a prime time for IPT's problem areas, especially disputes, transitions, and loneliness. Key takeaways for parents:• Try to understand the specific stressors behind an adolescent's symptoms rather than reacting to global, dramatic statements.• Always be alert to the possibility of suicidal ideation.• Communication barriers between teens and parents are common; a trusted third party (grandparent, therapist, family friend) can sometimes serve as a valuable bridge.The New Book: IPT Around the WorldThis book is now available open access for readers everywhere!The COVID-19 pandemic gave Dr. Weissman the unexpected opportunity to connect with IPT practitioners worldwide. What began as a routine update to the standard IPT manual grew into a sweeping collaborative volume covering more than 30 countries across Africa, Asia, Europe, and the Americas. Contributors were asked: What are you doing? What works? What doesn't? What adaptations did you need to make?Notable chapters include:• Uganda — IPT was introduced around 2003 amid civil war and a mental health crisis. A landmark clinical trial published in JAMA confirmed its effectiveness. Sean Mabry, a former WHO worker, went on to treat hundreds of thousands of people using IPT, even by telephone during the pandemic, and has now established a low-cost program in New Jersey.• China — After government engagement and training by Columbia experts, IPT became what practitioners called a “rapidly growing practice,” with books, training programs, and internet-based delivery.• Malaysia — IPT has been applied with refugees, using the “transitions” framework to help people process displacement and profound loss.• Africa (Ethiopia, Kenya, Mozambique, Senegal, Zambia, Uganda) — Adaptations have been made for cultural context, including how disputes are communicated and resolved within different family and community structures.• Japan and Hong Kong — Initial resistance to psychotherapy has given way to growing acceptance and translated materials.• United States special populations — Chapters cover Alaska Natives, people who are incarcerated, sexual and gender minorities, pre-adolescents, adolescents, and older adults.Cultural AdaptationsDr. Weissman shares a vivid example from Uganda: women in marital disputes are often encouraged not to confront their husbands directly, but to work through an elder who mediates. The underlying IPT principle, that the dispute is driving the symptoms, remains intact; only the implementation changes.Resources Mentioned• International Society of Interpersonal Psychotherapy (ISIPT) — volunteer-run, affordable membership, biannual international conference (10th meeting held in the UK, March 2024)• Dr. Weissman's new book on IPT across international sites — published Open Access, freely available to practitioners and researchers worldwide• Oxford University Press — publisher of the standard IPT manualAbout the GuestDr. Myrna Weissman is the Diana Goldman Kemper Family Professor of Epidemiology and Psychiatry at Columbia University's Vagelos College of Physicians and Surgeons and Mailman School of Public Health, and Chief of the Division of Translational Epidemiology at the New York State Psychiatric Institute. Alongside her late husband, Dr. Gerald Klerman, she co-developed Interpersonal Psychotherapy (IPT), now backed by over 140 clinical trials, translated into numerous languages, and recommended by the World Health Organization.

The ongoing outbreak of hantavirus infections that originated with passengers on the Dutch cruise ship MV Hondius in April has generated concerns across the globe. This very rare occurrence has led to a number of deaths, required quarantining of passengers and prompted emergency responses from public health authorities in multiple countries.  On this episode of Raise the Line from Elsevier, we're tapping the expertise of a leading authority on the subject, Dr. Jamie Childs of Yale University, to provide you with a scientific understanding of hantaviruses and what level of threat is posed by this situation. In short, Dr. Childs believes this is not the start of a pandemic. “The Andes variant involved here is one of the most dangerous hantaviruses, but it is totally controllable with contact tracing.” This timely conversation with host Lindsey Smith is informed by Dr. Childs' decades of hantavirus research as well as learnings from his role leading the CDC's environmental investigation during the landmark 1993 hantavirus outbreak in the Four Corners region of the American Southwest. And be sure to stay tuned to hear his concerns about the factors complicating containment of the current Ebola outbreak in East Africa. Note: this conversation was recorded on May 19th, 2026. Mentioned in this episode: Yale School of Public Health Yale Institute for Global Health If you like this podcast, please share it on your social channels. You can also subscribe to the series and check out all of our episodes at www.osmosis.org/podcast

Carlos Juan Finlay was a Cuban doctor who did a lot of work to understand the spread of Yellow Fever. But Walter Reed got most of the credit. Research: American Experience. “Carlos Finlay (1833-1915).” From The Great Fever. PBS. https://www.pbs.org/wgbh/americanexperience/features/fever-carlos-finlay/ Berenbrok, Dorothy E., "Latin Heritage Month. Carlos Juan Finlay: Outrageous, Courageous and Correct" (2015). Posters: Jefferson History. 3. https://jdc.jefferson.edu/jeffhistoryposters/3 "Carlos Juan Finlay." Encyclopedia of World Biography Online, Gale, 1998. Gale In Context: Opposing Viewpoints, link.gale.com/apps/doc/K1631002194/GPS?u=mlin_n_melpub&sid=bookmark-GPS&xid=bfeecc25. Accessed 29 Apr. 2026. Chaves-Carballo, Enrique. “Carlos J. Finlay: The mosquito man.” Hektoen International. 11/2/2020. https://hekint.org/2020/11/02/carlos-j-finlay-the-mosquito-man/ Corbitt, Duvon C. “Carlos J. Finlay, Cuban Physician.” The Hispanic American Historical Review, Vol. 45, No. 3 (Aug., 1965). Via JSTOR. https://www.jstor.org/stable/2511751 Del Regato, Juan A. “Carlos Juan Finlay (1833-1915).” Journal of Public Health Policy , 2001, Vol. 22, No. 1 (2001). Via JSTOR. https://www.jstor.org/stable/3343556 Faerstein, Eduardoa; Winkelstein, Warren Jrb. Carlos Juan Finlay: Rejected, Respected, and Right. Epidemiology 21(1):p 158, January 2010. | DOI: 10.1097/EDE.0b013e3181c308e0 Ferreira Moreno, Víctor Guillermo. “Evocation to the Dr. Carlos J. Finlay Barres on the centennial of his death.” Colombia medica (Cali, Colombia) vol. 47,1 63-6. 30 Mar. 2016 Finlay, Carlos J. “The Mosquito Hypothetically Considered as the Agent of Transmission of Yellow Fever.” Read before the Royal Academy of Medical, Physical and Natural Sciences Session of August 14th, 1881. https://archive.org/details/b33448541/page/590/mode/1up Finlay, Carlos Juan. “Trabajos selectos del Dr. Carlos J. Finlay. Selected papers of Dr. Carlos J. Finlay.” Habana. 1912. https://archive.org/details/trabajosselectos00finl Finlay, Charles. “Inoculations for Yellow Fever by Means of Contaminated Mosquitoes.” Published in The American Journal of the Medical Sciences, n.s. 102: 264-268, 1891. https://archive.org/details/b33445242/page/n4/mode/1up Finlay, Charles. “Yellow Fever: Its ‘Transmission by Means of the Culex Mosquito.” Published in The American Journal of the Medical Sciences, n.s. 92: 395-409, 1886. https://archive.org/details/b33435698/page/613/mode/1up Palmer, Steven. “A Cuban Scientist Between Empires: Peripheral Vision on Race and Tropical Medicine.” Canadian Journal of Latin American and Caribbean Studies / Revue canadienne desétudes latino-américaines et caraïbes, Vol. 35, No. 69, Special Issue: Landscapes of LatinAmerican Health, 1870-1970. Via JSTOR. https://www.jstor.org/stable/41800498 Spears, Ellen Griffith and Rosa López-Oceguera. “Carlos Juan Finlay, William Gorgas, and Walter Reed and the U.S. Army Yellow Fever Controversy: Competing Historical Memories.” Alabama Review The University of Alabama Press. Volume 74, Number 1, January 2021. https://doi.org/10.1353/ala.2021.0011 Stepan, Nancy. “The Interplay between Socio-Economic Factors and Medical Science: Yellow Fever Research, Cuba and the United States.” Social Studies of Science , Nov., 1978, Vol. 8, No. 4 (Nov., 1978). Via JSTOR. http://www.jstor.com/stable/284817 Thomas Jefferson University. “10 Notable Jefferson Alumni of the Past.” https://library.jefferson.edu/archives/exhibits/notable_alumni/juan_carlos_finlay.cfm Tone, John Lawrence. (2002) “How the mosquito (man) liberated Cuba.” History and Technology, 18:4, 277-308, DOI: 10.1080/07341512.2002.11417735 “Carlos J. Finlay.” 5/16/2023. https://www.unesco.org/en/prizes/carlos-j-finlay/about Woodall, Jack. "Yellow Fever." Infectious Diseases: In Context, edited by Brenda Wilmoth Lerner and K. Lee Lerner, vol. 2, Gale, 2008, pp. 925-931. In Context Series. Gale In Context: Opposing Viewpoints, link.gale.com/apps/doc/CX3045200265/GPS?u=mlin_n_melpub&sid=bookmark-GPS&xid=bf646a26. Accessed 29 Apr. 2026. See omnystudio.com/listener for privacy information.

Spine Health Researcher, Clinician, and Professor, Dr. Christine Goertz shares her life's work in her new book Take Your Back Back. RESEARCH & HEALTH POLICY CAREER I'm Christine Goertz, D.C., Ph.D. I have spent 35 years working with multi-disciplinary teams to conduct research studies and implement best practices designed to optimize care for patients with low back pain. CURRENT ROLE I am a Professor in Musculoskeletal Research at the Duke Clinical Research Institute and Vice Chair for the Implementation of Spine Health Innovation in the Department of Orthopaedic Surgery at Duke University. I am also an Adjunct Professor in the Department of Epidemiology, College of Public Health at the University of Iowa.  WHERE IT ALL BEGAN I received my Doctor of Chiropractic (D.C.) degree from Northwestern Health Sciences University in 1991 and a Ph.D. in Health Services Research, Policy and Administration from the School of Public Health at the University of Minnesota in 1999. ACCOMPLISHMENTS I have extensive experience in the administration of Federal grants, both as a PI and as a program official at the National Institutes of Health (NIH). I have received nearly $45 million in federal funding, as the principal investigator or co-principal investigator, primarily from NIH and the Department of Defense. I have also co-authored more than 135 peer-reviewed scientific papers. MAKING A GLOBAL IMPACT I am honored to have delivered invited lectures, keynote talks, clinical grand rounds, and plenary presentations worldwide. Topics include "Research, Its Not Just for Scientists Anymore," "In Search of the Holy Grail in Low Back Pain Treatment or Anything that Works at All," and " Nonpharmacological Approaches to Pain Management." Venues include the Patient Centered Outcomes Research Institute Annual Meeting, Georgetown University, Duke University School of Medicine, the American Physical Therapy Association's Combined Sections Meeting, the American Chiropractic Association Summit, the World Federation of Chiropractic Research Congress, and the European Chiropractic Union.  Resources: Dr. Goertz's website The Back Pain Chronicles Pain Trainer Take Your Back Back The Cox 8 Table by Haven Medical Find a Back Doctor  

In this episode of PICU Doc on Call, hosts Dr. Monica Gray and Dr. Pradip Kamat discuss a 15-year-old girl who attempted suicide by ingesting rat poison, acetaminophen, ibuprofen, and amlodipine. The episode focuses on long-acting anticoagulant rodenticides (LAARs), such as brodifacoum, which inhibit vitamin K epoxide reductase, causing delayed coagulopathy. Key topics include clinical presentation, diagnostic evaluation, and management, emphasizing vitamin K1 as the primary antidote and prothrombin complex concentrate or fresh-frozen plasma for major bleeding. The patient stabilized with aggressive supportive care, including vasoactive agents and NAC therapy, alongside psychiatric intervention. Listen to learn more!Show HighlightsClinical case of a 15-year-old girl who attempted suicide through polypharmacy ingestionIngestion of multiple substances, including chewable rat poison, acetaminophen, ibuprofen, and amlodipineDiscussion of toxicology related to long-acting anticoagulant rodenticides (LAARs) like brodifacoumSymptoms and clinical presentation following acute ingestion, including metabolic acidosis and elevated lactateDiagnostic evaluation and laboratory findings, including coagulation studies and liver function testsManagement strategies for LAAR poisoning, including the use of vitamin K and supportive careImportance of monitoring for delayed coagulopathy and serial INR testingConsideration of calcium channel blocker toxicity in the context of the patient's clinical instabilityOverview of the mechanisms of action of LAARs and their impact on vitamin K-dependent clotting factorsKey take-home points regarding the recognition and management of rodenticide ingestion in pediatric patientsReferencesReference: King N, Tran MH. Long-Acting Anticoagulant Rodenticide (Superwarfarin) Poisoning: A Review of Its Historical Development, Epidemiology, and Clinical Management. Transfus Med Rev. 2015 Oct;29(4):250-8.Reference 2: Feinstein DL, Akpa BS, Ayee MA, et al. The emerging threat of superwarfarins: history, detection, mechanisms, and countermeasures. Ann N Y Acad Sci. 2016 Jun;1374(1):111-22.

About this episode: A deadly Ebola outbreak in the Democratic Republic of the Congo and Uganda has been declared a global public health emergency by WHO. In this episode: infectious disease epidemiologist Emily Gurley explains why this outbreak is particularly concerning for a region managing existing crises and how public health systems are working to contain transmission and treat patients. Guest: Emily S. Gurley, PhD, MPH, is a professor in Epidemiology at the Johns Hopkins Bloomberg School of Public Health, where she focuses on infectious disease and outbreak investigation. Host: Stephanie Desmon, MA, is a former journalist, author, and the director of public relations and communications for the Johns Hopkins Center for Communication Programs. Show links and related content: WHO declares major outbreak of rare Ebola virus species an international emergency—Science US Imposes Ebola Travel Restrictions as CDC Says Risk Remains Low—Newsweek What else to know: The Ebola outbreak in Central Africa will be challenging to control, but decades of experience will help—The Uptake  Transcript information: Looking for episode transcripts? Open our podcast on the Apple Podcasts app (desktop or mobile) or the Spotify mobile app to access an auto-generated transcript of any episode. Closed captioning is also available for every episode on our YouTube channel. Contact us: Have a question about something you heard? Looking for a transcript? Want to suggest a topic or guest? Contact us via email or visit our website. Follow us: @‌PublicHealthPod on Bluesky @‌PublicHealthPod on Instagram @‌JohnsHopkinsSPH on Facebook @‌PublicHealthOnCall on YouTube Here's our RSS feed Note: These podcasts are a conversation between the participants, and do not represent the position of Johns Hopkins University.

What can a rare hantavirus outbreak on a cruise ship tell us about broader public health risks, and are there warning signs closer to home that we may be overlooking? After a Dutch vessel was linked to the Andes strain, questions emerge about how such diseases spread, what makes them dangerous, and whether other threats, including tick-borne illnesses, are already taking hold. We examine what is known about hantavirus, how it compares to more familiar risks, and what it could signal about shifting patterns in human and environmental health. Dr. Fahad Razak, an internist and epidemiologist at St. Michael's Hospital, looks at the implications for surveillance, preparedness, and public awareness. We then turn to a different kind of signal: the ways animals respond to changing conditions. If animals are constantly communicating, what might humans be missing, and could those observations offer insight into environmental change? Amelia Thomas, journalist and author of "What Sheep Think About the Weather," explores how animals interpret their surroundings, what their behaviours might reveal, and whether learning to pay closer attention could deepen our understanding of the forces shaping both animal and human health.See omnystudio.com/listener for privacy information.

The herbicide paraquat is so toxic it's banned in over 70 countries. But its use in the U.S. is growing, despite known links to Parkinson's disease. In southeastern Mississippi, an industrial plant is leaking tens of thousands of pounds of the chemical into the air. Environmental reporter Delaney Nolan and epidemiologist Beate Ritz join Host Flora Lichtman to discuss the implications of this leak, and what we know about how paraquat affects the body. Guests:  Delaney Nolan is an environmental reporter based in New Orleans. She reported this story for The Lens and the Mississippi River Basin Ag & Water Desk. Dr. Beate Ritz is a professor of epidemiology at UCLA in Los Angeles. Other episodes you may enjoy: Teasing Apart The Causes And Early Signs Of Parkinson's Workout Worms May Reveal New Parkinson's Treatments Want SciFri gear? Check out our new shop! Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that's keeping you up at night? Call us: 877-4-SCIFRI Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Katelyn Jetelina, founder and author of the newsletter Your Local Epidemiologist, talks about what public health authorities do and don't know about the strain of hantavirus on the MV Hondius cruise ship, what the risks are and what the reaction of US-based health officials has signaled about pandemic preparedness here. Photo: Specialist workers in full PPE carry boxes containing hazardous waste as they begin the process of disinfecting the cruise ship MV Hondius after it docked in the Port of Rotterdam following the recent hantavirus outbreak, on May 18, 2026 in Rotterdam, Netherlands. (Photo by Omar Havana/Getty Images) Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

West Side Market updates Cleveland's historic, 114-year-old West Side Market has been undergoing major change in recent years. First, it went through structural change, moving from longtime city management to nonprofit management back in 2024, something that residents and vendors had been calling for for years to improve conditions at the market. Now it's going through a major revitalization, as once the nonprofit team called the Cleveland Public Market Corporation began, it launched a years-long, $70 million transformation project funded in part by the city of Cleveland and City Council, as well as philanthropy and other government sources. But there's still some millions left to raise to complete the vision, and many months left to go until residents see completion of the project. In the meantime, there will be a lot of construction to wade through as you get your groceries and support local vendors. We'll discuss these updates on Tuesday's "Sound of Ideas" and learn what you can expect when you visit the market. Guests: - Rosemary Mudry, Executive Director, Cleveland Public Market Corporation - Don Whitaker, Owner, DW Whitaker Meats & Former President, United West Side Market Tenants Association - Jessy Harb, Co-owner of Harb's Produce What to know about hantavirus More than a dozen American cruise passengers are currently under a 42-day quarantine in Nebraska in a specialized medical facility after spending weeks aboard a ship hit with a deadly hantavirus outbreak that infected at least 11 people, including three who died. Hantavirus is a pathogen that some rodents carry that can sometimes infect humans. The passengers under quarantine are asymptomatic. This incident is harkening memories of another virus that caused a global pandemic six years ago. But health experts say hantavirus is not the same as COVID-19. We'll learn why by talking to a local epidemiologist. Guest: - Tara Smith, Ph.D., Professor of Epidemiology, Kent State University

Allergies have tripled - with hay fever, seasonal allergies, eczema and food intolerances now affecting millions of people. But why are allergy symptoms getting worse, and what does gut health have to do with it? In this episode, Adam Fox, a world-leading allergy Professor at King's College London, explains why allergies may be rising so fast, why many beliefs about allergies are wrong, and what new science reveals about your immune system, skin and gut. Professor Fox explores why some foods are more likely to trigger reactions, and why modern allergy science is increasingly focused on gut health. Adam also discusses why 90% of people told they are allergic to certain things may not actually be allergic, the difference between allergies and intolerances, and why some antihistamines may be doing you more harm than you realise. By the end of this episode, you will have some practical ways to manage hay fever and seasonal allergies, including which antihistamines experts now recommend avoiding, simple ways to reduce pollen exposure at home, and when allergy testing or desensitisation treatment may help. Adam explains how newer treatments are starting to retrain the immune system rather than simply suppress symptoms. If allergies barely existed a few hundred years ago, what changed? And could your gut now be shaping the way your immune system reacts to the world around you?

Chemical exposures in the womb can lead to what biologists call organizational effects - that is, impacts on the developing child that are irreversible. How were developmental problems associated with chemical exposures during pregnancy first discovered? And how did these discoveries influence policy? With me to discuss chemicals and child development is Tracey Woodruff. Tracey is a professor in the Department of Epidemiology and Population Health at Stanford University, where she co-leads the UCSF/Stanford Environmental Research and Translation for Health Center. She is an expert on environmental pollution exposures and impacts on health, with a focus on pregnancy, infancy and childhood, and health equity. Tracey was elected to the National Academy of Medicine in recognition of her pioneering work advancing environmental health and reproductive justice.

A cruise ship, a rare virus, and three dead passengers. It is the headline that has put us all on edge, but how worried should we be about hantavirus? In this episode of The Quicky, we speak with CSIRO Principal Research Scientist Professor Glenn Marsh to find out how this rodent-borne illness spreads, why a specific South American strain has experts concerned and whether Australia is prepared for a potential outbreak.

In a viral confession, Katy Talento — President Trump's former health advisor — revealed her role in keeping Robert F. Kennedy Jr. away from the White House, saying it was her job to “make this problem go away.” “I was a Harvard-trained infectious disease epidemiologist. I believed, religiously, that vaccines were the gold standard of public health interventions,” writes Talento. “Not because I had been shown the evidence for their effectiveness and safety in public health school… but because I had been trained in the orthodoxy of public health, where it was assumed that someone had studied this and it had been demonstrated at some point – so now we could all focus on more pressing matters, like how to get vaccines in more kids' arms around the world.” But slowly, she began to feel suspicious – and her research led her to switch sides. “[S]omething happened in late summer of 2021 – a set of legal contortions between Big Pharma and the FDA that started to make everything painfully clear,” she says in a May 2026 public apology to RFK for her part in keeping him away from the White House. In This Episode: Katy Talento joins Dr. Drew to expose the inner workings of the White House Domestic Policy Council, the DC establishment's efforts to sabotage RFK, and why she no longer trusts the medical consensus. A&E's Flash Shelton explains his unconventional strategies for helping homeowners take back their properties from squatters nationwide. Flash Shelton is the host of A&E's docu-series “Squatters,” which premieres with back-to-back episodes starting Tuesday, May 12th at 10pm and 10:30pm ET/PT. Shelton's journey began in 2019 when squatters took over his mother's vacant home in Northern California. After navigating the eviction process himself, he has gone on to help property owners nationwide in more than 100 cases. Learn more at https://www.aetv.com/ Katy Talento is a licensed health benefits consultant, epidemiologist, and health care reformer. As the top health advisor at the White House Domestic Policy Council, she spearheaded policies on health care pricing, prescription drugs, and the opioid crisis. She earned her graduate degree in Epidemiology from Harvard School of Public Health. She is CEO of AllBetter Health. Follow at https://x.com/katytalento 「 SUPPORT OUR SPONSORS 」 • STRONG CELL – If you want to feel more like your younger self, go to https://strongcell.com/ and use code DREW for 20% off. ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠• FATTY15 – The future of essential fatty acids is here! Strengthen your cells against age-related breakdown with Fatty15. Get 15% off a 90-day Starter Kit Subscription at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://drdrew.com/fatty15⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ • PALEOVALLEY - "Paleovalley has a wide variety of extraordinary products that are both healthful and delicious,” says Dr. Drew. "I am a huge fan of this brand and know you'll love it too!” Get 15% off your first order at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://drdrew.com/paleovalley⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ • THE WELLNESS COMPANY - Counteract harmful spike proteins with TWC's Signature Series Spike Support Formula containing nattokinase and selenium. Learn more about TWC's supplements at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://twc.health/drew⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 「 ABOUT THE SHOW 」 This show is for entertainment and/or informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment. Executive Producers • Kaleb Nation - ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://kalebnation.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ • Susan Pinsky - ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://x.com/firstladyoflove⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Content Producer • Emily Barsh - ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://x.com/emilytvproducer⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Hosted By • Dr. Drew Pinsky - ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://x.com/drdrew⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Learn more about your ad choices. Visit megaphone.fm/adchoices

Can faster access to real-world data actually change patient outcomes, or are we still too reliant on controlled clinical trials to see the full picture? In this episode, I sit down with Dr. Alex Asiimwe, Executive Director of Epidemiology at Gilead Sciences, to explore a topic that doesn't get enough attention in the AI conversation, real-world evidence. While much of the industry focuses on AI in drug discovery or diagnostics, Alex brings a different perspective, one rooted in what happens after treatments reach real patients in the real world. As he explains, clinical trials may be the gold standard, but they are still controlled environments. Real-world evidence is where we begin to understand how treatments perform across diverse populations, healthcare systems, and everyday conditions. What stood out in our conversation is just how messy and fragmented that real-world data can be. Much of it is not collected for research purposes, which means it takes months, sometimes up to a year, to clean, structure, and analyze before it can inform decisions. Alex shares how AI is beginning to change that, not by replacing human expertise, but by automating the most time-consuming parts of the process. If that timeline can be cut in half, the impact is immediate. Faster evidence means faster decisions, and in healthcare, delays in evidence can directly affect patient outcomes. We also explore what Alex describes as the "analytics gap," the disconnect between where data exists and where insights are actually generated. Today, much of the evidence used in drug development still comes from limited datasets, often from a single country or region. Yet the treatments themselves are global. That mismatch creates blind spots, particularly in low and middle-income countries where data is often unstructured, fragmented, or simply not accessible. AI has the potential to standardize and unlock that data, helping to create a more complete and representative view of patient populations worldwide. Of course, the challenges are not just technical. Trust, governance, and politics all play a role in whether data can be shared and used effectively. Alex is clear that the biggest barrier is not the science or the analytics, it is building trust between organizations, governments, and communities. Without that, even the most advanced AI models cannot deliver meaningful outcomes. This conversation also touches on the importance of collaboration, not just between healthcare organizations and technology providers like SAS, but across the global ecosystem. Alex highlights how partnerships, open standards, and shared frameworks can help close the analytics gap and accelerate progress in areas like HIV prevention, where understanding real-world patient behavior is critical. As we wrap up, one message comes through clearly. AI is not a miracle solution, and it will not transform healthcare overnight. But when applied to the right parts of the workflow, especially around data preparation and evidence generation, it can create measurable, meaningful change. So as healthcare leaders look to move beyond pilots and into real impact, the question becomes, are we focusing on the right problems, and are we ready to open up the data needed to solve them?  Useful Links Connect with Dr. Alex Asiimwe OHDSI – Observational Health Data Sciences and Informatics Please check our partners of Tech Tech Talks Network Learn more about the NordLayer Browser  

Today, we're diving into a topic that should be getting far more attention: Cardiovascular disease in women. Heart disease is one of the leading causes of death in women—yet it's often under-addressed, oversimplified, and misunderstood in clinical practice. Most women are told: “Eat better. Take this prescription.” But that approach misses something critical. Full citation list:    •    Hall, Kevin D., et al. “Ultra-Processed Diets Cause Excess Calorie Intake and Weight Gain: An Inpatient Randomized Controlled Trial of Ad Libitum Food Intake.” Cell Metabolism, vol. 30, no. 1, 2019, pp. 67–77.e3. Supports the core causal point that ultra-processed foods drive higher intake and weight gain even under controlled feeding conditions; this is not a women-specific lipid paper, but it is the cleanest experimental anchor for why UPFs create a high-throughput metabolic environment.     •    El Khoudary, Samar R., et al. “Menopause Transition and Cardiovascular Disease Risk: Implications for Timing of Early Prevention: A Scientific Statement From the American Heart Association.” Circulation, vol. 142, no. 25, 2020, pp. e506–e532. Supports the midlife women's frame: across the menopause transition, LDL-C and ApoB rise, metabolic risk shifts, and cardiovascular prevention needs to become more deliberate during this window. This supports the “why I care about lipids in endocrine care” part of the episode.     •    Derby, Carol A., et al. “Lipid Changes During the Menopause Transition in Relation to Age and Weight: The Study of Women's Health Across the Nation.” American Journal of Epidemiology, vol. 169, no. 11, 2009, pp. 1352–61. Foundational SWAN paper establishing that the menopause transition itself — not just chronological aging — is associated with adverse lipid shifts in midlife women. This is the original observation that the timing argument rests on.     •    Wu, Bingjie, et al. “Trajectories of Blood Lipids Profile in Midlife Women: Does Menopause Matter?” Journal of the American Heart Association, vol. 12, no. 22, 2023, e030388. Supports the claim that LDL-C, total cholesterol, and ApoB follow distinct trajectory patterns through the menopause transition, with subgroups of women showing rising lipids in the years before the final menstrual period — useful for the timing argument that body and symptom changes can precede the obvious lab story.     •    Matthews, Karen A., et al. “Age at Menopause in Relationship to Lipid Changes and Subclinical Carotid Disease Across 20 Years: Study of Women's Health Across the Nation.” Journal of the American Heart Association, vol. 10, no. 18, 2021, e021362. Supports the point that ApoB and Apo A1 changes cluster around the final menstrual period and that adverse lipid shifts in the early postmenopausal years track with subclinical carotid disease later — connects menopausal timing to the longer cardiovascular arc rather than a one-time lab blip.     •    De Oliveira-Gomes, Diana, et al. “Apolipoprotein B: Bridging the Gap Between Evidence and Clinical Practice.” Circulation, vol. 150, no. 1, 2024, pp. 62–79. Supports the practical ApoB explanation: ApoB reflects atherogenic particle burden and outperforms LDL-C for ASCVD risk prediction in many settings, but adoption lags because clear apoB targets and triggers are still lacking in mainstream guidelines. Good support for the public-service “what the hell is ApoB anyway?” section.     •    Williamson, Laura. “The Slowly Evolving Truth About Heart Disease and Women.” American Heart Association News, 9 Feb. 2024, heart.org/en/news/2024/02/09/the-slowly-evolving-truth-about-heart-disease-and-women. Supports the broader clinical framing that women remain underrecognized or undertreated in cardiovascular care and that women's heart disease still needs better public and clinical communication. This is more public-facing than mechanistic, but useful for your opening frame. Dr. Brendan McCarthy is the founder and Chief Medical Officer of Protea Medical Center in Arizona. With over two decades of experience, he's helped thousands of patients navigate hormonal imbalances using bioidentical HRT, nutrition, and root-cause medicine. He's also taught and mentored other physicians on integrative approaches to hormone therapy, weight loss, fertility, and more. If you're ready to take your health seriously, this podcast is a great place to start.

Episode 201, Jay Cutler & Manager Matt bring on Dr Zach Pallikaros from the UK. Dr. Zach is a competitive bodybuilder, has a PhD in Epidemiology and is the owner of Pumping Iron Gym in london! Also making an appearance is Dave Bourlet from JayCutler TV! TRT Kingdom - https://trtkingdom.com/?ref=cutlercast Cutler Nutrition - http://jaycutler.com/cutlercast  

What if one of the most popular health trends in the world, fasting, is actually being done wrong by millions of people? In this powerful and deeply grounded conversation, Darin sits down with world-renowned longevity expert Dr. Valter Longo to cut through the noise surrounding fasting, dieting, and modern health trends. From the dangers of prolonged fasting and skipping breakfast to the science behind the Fasting Mimicking Diet, this episode delivers a reality check rooted in decades of clinical research, not social media hype. They explore the intersection of longevity, cancer, metabolism, and modern lifestyle, unpacking why extreme protocols fail, why simplicity wins, and why aligning with your biology is the true key to a long, disease-free life.     What You'll Learn Why most fasting trends are misapplied and potentially harmful The safest and most sustainable fasting window for longevity Why skipping breakfast is linked to increased mortality risk The science behind the Fasting Mimicking Diet (FMD) How fasting impacts cancer cells vs healthy cells The hidden risks of GLP-1 weight loss drugs Why "easy solutions" often lead to worse long-term outcomes The importance of circadian rhythm in metabolism The truth about protein intake and long-term health risks Why slow, consistent change beats every "quick fix"     Chapters 00:00:00 – Opening: SuperLife mission and framing the conversation 00:00:32 – Sponsor: Therasage infrared sauna and heat therapy benefits 00:03:16 – Introduction: Dr. Valter Longo and longevity research 00:03:40 – The fasting craze: what's misunderstood 00:04:05 – Documentary discussion: science vs entertainment 00:05:13 – Why education must outweigh entertainment 00:06:19 – The danger of social media health advice 00:07:00 – Food systems, pharma, and systemic health issues 00:07:58 – Why clinical trials matter more than anecdotes 00:08:15 – Framing fasting: trends vs real science 00:08:59 – The problem with DIY fasting 00:10:03 – The safest fast: 12-hour daily fasting explained 00:10:38 – Risks of long fasting: cholesterol, gallstones, mortality 00:11:09 – Why skipping breakfast increases health risks 00:11:49 – 12-hour fasting as the most sustainable protocol 00:12:13 – Modern eating habits: 15+ hour eating windows 00:12:34 – Why extreme diets fail long-term 00:13:37 – Feasibility: why most people won't sustain extremes 00:13:56 – Introducing the Fasting Mimicking Diet (FMD) 00:14:53 – Risks of fasting without personalization 00:15:20 – Why fasting can do more harm than good 00:15:45 – Sponsor: Alkemis Paint, indoor toxicity and non-toxic paint 00:18:42 – Clinical trials: meal timing and metabolic health 00:19:03 – Morning vs evening calorie intake study 00:19:56 – Why late eating disrupts metabolism and sleep 00:20:21 – Epidemiology: skipping breakfast increases mortality 00:21:18 – Circadian rhythm and digestion explained 00:22:11 – Evolutionary biology of eating patterns 00:22:41 – Circadian violations and long-term consequences 00:23:11 – Short-term benefits vs long-term risks 00:24:01 – Why slow progress leads to real results 00:24:49 – Realistic timelines: years, not weeks 00:25:19 – The modern system pushing unhealthy behaviors 00:25:48 – GLP-1 drugs: convenience vs consequences 00:26:13 – The danger of "effortless health" 00:27:13 – Exercise analogy: why effort still matters 00:28:06 – The "pill for everything" mentality 00:28:48 – Finding balance between extremes 00:29:25 – Sponsor: Our Place, non-toxic cookware and health 00:31:12 – Personalization vs one-size-fits-all health 00:31:51 – GLP-1 risks: depression, anxiety, muscle loss 00:32:36 – Natural vs drug-induced weight loss differences 00:33:29 – Rebound weight gain and hormonal suppression 00:34:14 – Supplements vs fixing root causes 00:34:37 – What is the Fasting Mimicking Diet 00:35:05 – Cancer research: fasting and treatment synergy 00:36:13 – How FMD mimics fasting while protecting the body 00:37:06 – Gut health and microbiome benefits 00:38:32 – FMD vs water-only fasting outcomes 00:39:26 – Clinical trials: Crohn's and colitis remission 00:40:03 – Importance of independent research 00:41:20 – Longevity through the lens of fatherhood 00:42:23 – Concerns about AI and children's development 00:43:25 – Social isolation vs digital addiction 00:44:25 – The need for balance in technology use 00:45:10 – AI overdependence and cognitive decline 00:46:18 – Mental health crisis and modern technology 00:47:10 – Reclaiming creativity and human agency 00:48:43 – Fasting and cancer: immune system activation 00:49:53 – Why cancer cells resist fasting signals 00:51:10 – The "desert analogy" for cancer vulnerability 00:52:54 – Combining fasting with therapies 00:54:07 – Future of treatment: precision targeting 00:55:14 – Early detection and personalized interventions 00:56:12 – Where fasting fits in cancer care today 00:57:31 – The protein debate: how much is too much 00:58:17 – Protein intake guidelines explained 00:59:07 – Quality vs quantity of protein 01:00:18 – SuperLife Patreon and accessing exclusive content 01:01:21 – The protein obsession problem 01:02:00 – Children consuming excessive protein 01:03:18 – Portion control and dietary awareness 01:04:07 – Risks of excessive protein intake 01:05:04 – Minimal benefits vs long-term risks 01:06:12 – Longevity populations and low protein intake 01:08:00 – The future of nutrition science 01:12:00 – Final reflections on longevity and health 01:15:00 – Closing thoughts: aligning with biology     Thank You to Our Sponsors Therasage: Go to www.therasage.com and use code DARIN20 at checkout for 20% off Alkemis: Go to alkemispaint.com and use code DARIN10 for 10% off your order. Our Place: Toxic-free, durable cookware that supports healthy cooking. Use code DARIN for 10% off at fromourplace.com.     Join the SuperLife Community Get Darin's deeper wellness breakdowns — beyond social media restrictions: Weekly voice notes Ingredient deep dives Wellness challenges Energy + consciousness tools Community accountability Extended episodes Join for $7.49/month → https://patreon.com/darinolien     Find More from Dr. Valter Longo Website: valterlongo.com Instagram: @prof_valterlongo Get His New Book: Fasting Cancer     Find More from Darin Olien: Instagram: @darinolien Podcast: SuperLife Podcast Website: superlife.com Book: Fatal Conveniences New Show: Roadmap to Happiness     Key Takeaway "The path to longevity isn't found in extreme protocols or quick fixes, it's found in consistency, alignment, and understanding your biology. When you stop chasing shortcuts and start working with your body instead of against it, that's when real transformation happens, not just in how long you live, but in how well you live."

"The rates of fractures are highest in the high milk drinking countries, basically North America, Scandinavia, Denmark, and they're lowest in countries that actually don't consume milk at all." Today, we're joined by one of the most influential and widely cited figures in nutrition science. Dr. Walter Willett, Professor of Epidemiology and Nutrition at the Harvard T.H. Chan School of Public Health, has published over 2,000 papers across four decades. His work includes some of the largest and most rigorous studies on diet and chronic disease ever conducted. He is the author of several books, including the bestselling Eat, Drink, and Be Healthy, which challenged prevailing nutrition dogma and offered a clearer, evidence-based path forward. In this conversation, we examine the eating patterns most closely linked to longevity—for both human health and the health of the planet—the rise of foods designed for convenience rather than nourishment, and the risks they pose. We also break down the practical steps that offer the greatest protection against illness. So tune in for the rare opportunity to hear from a scientist and physician whose work continues to define the boundaries of nutrition. What we discuss: The potential risks of dairy consumption during adolescence in relation to bone health. Dairy-free sources of calcium and how to meet needs without milk. Concerns with current dietary guidelines and how they may mislead the public. Why plant protein sources are preferable to animal sources. The Planetary Health Diet and what it emphasizes. How diet influences susceptibility to infectious diseases, especially in children. The types of processed foods most harmful to health. The primary drivers of the obesity epidemic. Practical tips for eating healthier with limited access to fresh foods. Key principles to follow when navigating conflicting nutrition advice.  Resources: Walter C. Willett | Harvard T.H. Chan School of Public Health The Nutrition Source Eat, Drink, and Be Healthy: The Harvard Medical School Guide to Healthy Eating 1 Million Tables Click the link below to learn about the FISCAL Act https://switch4good.org/fiscal-act/ Share the website and get your resources here https://kidsandmilk.org/ Dairy-Free Swaps Guide: Easy Anti-Inflammatory Meals, Recipes, and Tips https://switch4good.org/dairy-free-swaps-guide SUPPORT SWITCH4GOOD https://switch4good.org/support-us/ ★☆★ JOIN OUR PRIVATE FACEBOOK GROUP ★☆★  https://www.facebook.com/groups/podcastchat ★☆★ SWITCH4GOOD WEBSITE ★☆★ https://switch4good.org/ ★☆★ ONLINE STORE ★☆★ https://shop.switch4good.org/shop/ ★☆★ FOLLOW US ON INSTAGRAM ★☆★ https://www.instagram.com/Switch4Good/ ★☆★ LIKE US ON FACEBOOK ★☆★ https://www.facebook.com/Switch4Good/ ★☆★ AMAZON STORE ★☆★ https://www.amazon.com/shop/switch4good

Dr. Tesha Monteith talks with Ayesha Sohail about her abstract titled "Global Burden of Headache Disorders in Older Adults (Aged ≥ 55 Years) from 1990-2021: An Analysis of Epidemiology, Trends, and Socioeconomic Disparities."  Read more about this abstract on the AAN website. 

Bird flu has flown off the national news radar, with only scattered, local reports of dead birds in parks and poultry farms. Is it simply no longer a concern, or have cuts to federal science funding disrupted monitoring for this disease? Airborne pathogens expert Seema Lakdawala gives a flyover view on where bird flu stands today, and whether the government's current monitoring efforts are enough to help prevent another pandemic. Guest: Dr. Seema Lakdawala is co-director of the Center for Transmission of Airborne Pathogens and an associate professor at Emory University in Atlanta, Georgia. Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.

 If you lose a spouse, you're a widow. If you lose your parents, an orphan. But we don't have the language for someone who lost a sibling – your first friend, your first ally, your first enemy (probably, at least temporarily). Grief always feels like a gut punch, but losing a sibling is a unique kind of pain that we don't talk about enough.  So today, I'm joined by Steph Wittels Wachs, former TTFA guest and sister of comedy legend Harris Wittels, who died in 2015 of an accidental overdose. We're talking about what losing a sibling means and sharing the notes, advice and insights from people who know what it's like to live in the world without their siblings. Cited in this episode: Rogne, S., Grotta, A., Liu, C., Berg, L., Saarela, J., Kawachi, I., Hiyoshi, A., & Rostila, M. (2025). All-cause mortality around the anniversary of a sibling's death: findings from Swedish National Register Data. AMERICAN JOURNAL OF EPIDEMIOLOGY. https://doi.org/10.1093/aje/kwaf213  Tatjana Gazibara, Katherine A Ornstein, Christina Gillezeau, Melissa Aldridge, Mogens Groenvold, Merete Nordentoft, Lau Caspar Thygesen, Bereavement Among Adult Siblings: An Examination of Health Services Utilization and Mental Health Outcomes, American Journal of Epidemiology, Volume 190, Issue 12, December 2021, Pages 2571–2581, https://doi.org/10.1093/aje/kwab212  Davidson, D. (2018). Sibling loss - disenfranchised grief and forgotten mourners. Bereavement Care, 37(3), 124–130. https://doi.org/10.1080/02682621.2018.1535882   Herberman Mash, H. B., Fullerton, C. S., & Ursano, R. J. (2013). Complicated Grief and Bereavement in Young Adults Following Close Friend and Sibling Loss. Depression & Anxiety (1091-4269), 30(12), 1202–1210. https://doi.org/10.1002/da.22068     Watch us on YouTube here! Get this episode ad-free here! Listen to Geoffrey's album on Spotify and Apple! LINKS TO RELATED EPISODES! https://feelingsand.co/podcasts/terrible-thanks-for-asking/86-sundays/  https://feelingsand.co/podcasts/terrible-thanks-for-asking/what-does-all-this-loss-mean/  Don't you want someone to take care of you?  _ Right now, go to Quince.com/TFA for free shipping and 365-day returns. That's a full year to wear it and love it. And you will. Now available in Canada, too. Don't keep settling for clothes that don't last. Go to Quince.com/TFA for free shipping and 365-day returns. Quince.com/TFA Shop my favorite bras and underwear at SKIMS.com. After you place your order, be sure to let them know we sent you! Select podcast in the survey and be sure to select our show in the dropdown menu that follows. Right now, our listeners get an additional 15% off any annual membership at MASTERCLASS.com/TFA. That's 15% off at MASTERCLASS.com/TFA. With evening and weekend course options, Fordham's online MSW lets you keep working while earning your degree, completing the program in as few as 16 months. Learn more and apply at fordham.edu/TTFA. Learn more about your ad choices. Visit megaphone.fm/adchoices