Podcasts about Epidemiology

rWotD Episode 3338: Forensic epidemiology Welcome to random Wiki of the Day, your journey through Wikipedia's vast and varied content, one random article at a time.The random article for Wednesday, 24 June 2026, is Forensic epidemiology.The discipline of forensic epidemiology (FE) is a hybrid of principles and practices common to both forensic medicine and epidemiology. FE is directed at filling the gap between clinical judgment and epidemiologic data for determinations of causality in civil lawsuits and criminal prosecution and defense.Forensic epidemiologists formulate evidence-based probabilistic conclusions about the type and quantity of causal association between an antecedent harmful exposure and an injury or disease outcome in both populations and individuals. The conclusions resulting from an FE analysis can support legal decision-making regarding guilt or innocence in criminal actions, and provide an evidentiary support for findings of causal association in civil actions.Applications of forensic epidemiologic principles are found in a wide variety of types of civil litigation, including cases of medical negligence, toxic or mass tort, pharmaceutical adverse events, medical device and consumer product failures, traffic crash-related injury and death, person identification and life expectancy.This recording reflects the Wikipedia text as of 01:19 UTC on Wednesday, 24 June 2026.For the full current version of the article, see Forensic epidemiology on Wikipedia.This podcast uses content from Wikipedia under the Creative Commons Attribution-ShareAlike License.Visit our archives at wikioftheday.com and subscribe to stay updated on new episodes.Follow us on Mastodon at @wikioftheday@masto.ai.Also check out Curmudgeon's Corner, a current events podcast.Until next time, I'm standard Joey.

Maternity care and its shortcomings will be in the spotlight over the next fortnight, as the biggest maternity inquiry in the history of NHS England prepares to report its findings. The independent review by former midwife, Donna Ockenden, has looked into maternity services at Nottingham University Hospitals NHS Trust. Meanwhile new figures from the Royal College of Midwives show that more than nine out of 10 of those polled felt unsafe staffing levels are directly impacting the quality of care they provide for women and babies. Next week we'll also hear the recommendations of a national review by Baroness Amos. BBC's social affairs correspondent, Michael Buchanan, talks to presenter Nuala McGovern about what we know so far. Joanna Cherry was elected as an MP in 2015, part of the SNP landslide when they took 56 out of 59 Scottish seats, just a year after the referendum on Scottish independence resulted in a No vote. Her memoir, Keeping the Dream Alive, captures the disappointment and euphoria of that time. Joanna went on to lose her seat in 2024 and has become a vocal critic of the party, and of Nicola Sturgeon's leadership. She was also well-known for expressing gender-critical views and concerns at a time when the SNP was trying to deliver a gender self-ID law in Scotland. She joins presenter Nuala McGovern to talk about that "tumultuous decade" in Scottish politics.A new study from the Universities of Exeter and Bristol is looking into how heavy periods impact daily life. Led by Gemma Sharp, a Professor of Epidemiology at Exeter, researchers will collect real-time data from thousands of participants to help us understand the relationship between periods - particularly heavy periods - and our energy levels, sleep and mood. Did you know that mini golf has feminist roots? A playful and ‘playable' exhibition, The Art of Mini Golf, has just opened at the Battersea Arts Centre in London, channelling the inclusive, subversive spirit of the game's female founders. Nuala's joined by curator Grace Herbert and one of the featured artists, Delaine Le Bas, to hear more about mini golf's hidden history and the art it's inspired.Presented by: Nuala McGovern Produced by: Sarah Jane Griffiths

Epidemiology is the study of how and why diseases affect different groups of people, and what the science increasingly shows is that preventing disease and preserving health are deeply connected. In this episode, we focus on endometrial cancer, a disease where many risk factors are within our control. We speak with Immaculata De Vivo, PhD, professor in the Department of Epidemiology at the Harvard T.H. Chan School of Public Health, about how lifestyle factors like movement, nutrition, stress management, and social connection can influence our biology and long-term health. We also explore the biological impact of chronic stress in cancers like endometrial cancer and discuss how listeners can feel more informed, empowered, and proactive during healthcare visits. Credits Host: Neha Pathak, MD, FACP, DipABLM Producer/Editor: Lauren Summers Show Notes: Lauren Summers Guest: Immaculata De Vivo, PhD See omnystudio.com/listener for privacy information.

Plant-based diets cut risk for cancer, COVID, and early death—even when adopted later in life. The science is clear: food is powerful medicine. #VeganHealth #CancerPrevention #FoodIsMedicine #HealthTalks

BUFFALO, NY — June 18, 2026 — A new #research paper was #published in Volume 18 of Aging on May 26, 2026, titled “Early-life determinants of cardiometabolic outcomes and accelerated biological ageing in Colombia.” The study was led by first and corresponding author Juan Carlos Rivillas from the Department of Epidemiology and Biostatistics, MRC Centre for Environment and Health, School of Public Health, Imperial College London, United Kingdom. Experiences during childhood can shape health for decades. Adverse childhood experiences (ACEs), such as emotional abuse, domestic violence, food insecurity, poor health, and forced displacement, have long been linked to chronic disease. However, less is known about how these early-life hardships may influence biological aging itself. In this study, researchers examined whether childhood adversity is associated with cardiometabolic disease and accelerated biological aging among older adults in Colombia. The investigators analyzed data from 3,385 adults aged 60 years and older who participated in the nationally representative SABE-Colombia study. Five forms of childhood adversity experienced before age 15 were evaluated: emotional abuse, domestic violence, poor childhood health, food scarcity, and forced migration related to Colombia's armed conflict. Biological aging was estimated using the Klemera-Doubal Method for Biological Age, a biomarker-based measure that compares biological age with chronological age. Full press release - https://aging-us.net/2026/06/18/childhood-adversity-may-leave-lasting-biological-scars-decades-later/ DOI - https://doi.org/10.18632/aging.206384 Corresponding author - Juan Carlos Rivillas - j.rivillas-garcia20@imperial.ac.uk Abstract video - https://www.youtube.com/watch?v=5w6vgFzjcNQ Sign up for free Altmetric alerts about this article - https://aging.altmetric.com/details/email_updates?id=10.18632%2Faging.206384 Keywords - aging, adverse childhood experiences, forced childhood migration, biological ageing, cardiometabolic outcomes, life course epidemiology To learn more about the journal, please visit https://www.Aging-US.com​​ and connect with us on social media at: Bluesky - https://bsky.app/profile/aging-us.bsky.social ResearchGate - https://www.researchgate.net/journal/Aging-1945-4589 X - https://twitter.com/AgingJrnl Facebook - https://www.facebook.com/AgingUS/ Instagram - https://www.instagram.com/agingjrnl/ LinkedIn - https://www.linkedin.com/company/aging/ Reddit - https://www.reddit.com/user/AgingUS/ Pinterest - https://www.pinterest.com/AgingUS/ YouTube - https://www.youtube.com/@Aging-US Spotify - https://open.spotify.com/show/1X4HQQgegjReaf6Mozn6Mc MEDIA@IMPACTJOURNALS.COM

Why do some kids and teens get overly frustrated and bored when it's time to turn off their video games? How to know when game playing has become excessive? What are tips that all families should know for ensuring healthy video game play? In today's episode of The Screenagers Podcast, Dr. Delaney Ruston explores these issues along with a new model of brain biology to help explain irritability and boredom associated with video gaming. We hear from teens along with psychiatrist Dr. Clifford Sussman who specializes in helping young people regain tech balance. We also hear from Andrew Fulton who was in the film, Screenagers, when he was getting treatment at an internet rehab center, and is now working at the same center helping others recover from video game overuse.   Additional Links Andrew in this episode works at the internet recovery center called reStart To learn more about Dr. Clifford Sussman, go to his website. Dr. Sussman et al.,  Internet and Video Game Addictions: Diagnosis, Epidemiology and Neurobiology.   Here are links to some Tech Talk Tuesday articles about video games: Digital Binging, Is it a Problem? Why 3 Hours is Too Much Fake Identities and Real Concerns Watch What Happens When Kids Have No Screen Time Rules ‍ Additional Resources Screenagers Website Bring Screenagers to Your Community

“Confounding, Confounding, Confounding” is like the epidemiologist's version of “Marcia, Marcia, Marcia” from the Brady Bunch. To discuss Chapter 7 of Causal Inference: What If, we welcome Dr. Ashley Naimi. In this chapter, we discuss confounding as a central problem when estimating causal effects from observational data. The chapter emphasizes that confounding is not just an imbalance in covariates across exposure groups, but a causal problem that depends on the underlying structure of how treatment, outcome, and other variables are related. In this episode, Dr. Naimi helps explain concepts related to confounding, exchangeability, and faithfulness. We (try to) talk through confounding-related DAGs and how they are a useful tool to understand confounding bias.  This episode shows why confounding gets so much attention in epidemiology: it is everywhere, often misunderstood, and, like Marcia Brady, it has a way of stealing the spotlight.

I speak with Johnathan Jarecki, undergraduate science student and host of The Signal Podcast, on all things photobiology. We discuss the full solar spectrum and how ultraviolet, visible, blue, red and near-infrared light each affect human physiology, including the POMC pathway, nitric oxide and blood pressure, and the evidence on sunlight, skin cancer and the vitamin D paradox. We also discuss how artificial light at night suppresses melatonin and disrupts the circadian control of DNA repair, cardiovascular health, and metabolism. TIMESTAMPS03:25 Dr. Max Gulhane04:02 Dr. Gulhane's Love for Science and Medicine09:01 What is Light?12:52 Sunlight Broken Down as a Nutrient14:02 Ultraviolet Light: Sunlight Is More Than Vitamin D15:56 POMC21:38 UVA/UVB on Cardiometabolic Health24:40 Big Picture of UV Light28:41 Sunlight, Skin Cancer, Dermatology Messaging, The Vitamin D Paradox35:10 Blue Light, Artificial Light at Night (ALAN), Mechanisms38:50 Sponsor: Daylight Computer40:34 ALAN, Epidemiology, Cancer, Heart Disease45:04 DNA Repair Mechanisms, Circadian Control47:27 Melanopsin (OPN4), Blue Light, UV Susceptibility53:25 Red, Infrared, Photobiomodulation, Metabolism01:00:08 Blue Light, Metabolism, and the Built Environment01:05:19 Photobiology of Atherosclerosis01:10:11 Blue Light on Cardiovascular Function01:12:25 Three M's of Circadian Health01:18:43 Sunlight, Testosterone, and Reproductive BehaviorFull show notes: https://docs.google.com/document/d/15zOnh_l6WOe6237CbQrFPkeoQjUZXIm9Ul4ncQTNXDQ/edit?pli=1&tab=t.0Show sponsors:

The World Health Organization defines health equity as a public health concept describing equity of access to health resources for genetic, socio-environmental, and economic determinants of health, varying according to individuals, families, and social or societal groups. Concerns about data equity have surfaced, which may result in many populations, including those in rural areas with disabilities, experiencing homelessness or living in low and middle-income regions of the world, being underrepresented in health data sets. This can lead to biased findings and suboptimal health outcomes for certain subgroups, which is the focus of this episode of Stats+Stories with guest Bhramar Mukherjee. Dr. Bhramar Mukherjee is the inaugural Senior Associate Dean of Public Health Data Science and Data Equity and the Anna M. R. Lauder Professor of Biostatistics, as well as Professor of Epidemiology and of Statistics and Data Science at Yale University. Among her many honors, she was elected to the US National Academy of Medicine in 2022.

Send us Fan MailIn this episode of MedEvidence, host Dr. Michael Koren speaks with epidemiologist Dr. Hannah Gardener about how everyday exposures may influence long-term health outcomes.Dr. Gardener shares her journey from neuroscience and epidemiology training at Harvard to her current work studying stroke, dementia, and environmental risk factors. She explains how personal life experiences sparked her interest in environmental health and led her to examine how early-life and daily exposures can shape disease risk across the lifespan.The conversation explores her research on diet soda consumption and its surprising associations with vascular outcomes, including stroke, heart disease, and cognitive decline. She breaks down what “prospective cohort studies” really mean and how to interpret findings without overgeneralizing results.The discussion then expands to PFAS, often called “forever chemicals”, which are widely used in consumer products and persist in the environment and human body. Dr. Gardener explains where these chemicals are found, what health effects have been observed in the research, and practical, evidence-based strategies individuals can use to reduce exposure.This episode offers a thoughtful, research-driven look at how environmental factors, diet choices, and chemical exposures intersect with long-term brain and cardiovascular health—and what can realistically be done today to reduce risk.Be a part of advancing science by participating in clinical research.Have a question for Dr. Koren? Email him at askDrKoren@MedEvidence.comListen on SpotifyListen on Apple PodcastsWatch on YouTubeShare with a friend. Rate, Review, and Subscribe to the MedEvidence! podcast to be notified when new episodes are released.Follow us on Social Media:FacebookInstagramX (Formerly Twitter)LinkedInWant to learn more? Checkout our entire library of podcasts, videos, articles and presentations at www.MedEvidence.comMusic: Storyblocks - Corporate InspiredThank you for listening!

Unprocessed red meat and cancer risk remains one of the most debated topics in nutrition science, partly because the evidence is often presented in overly simplistic terms. The key question is not whether to adopt a vague "balanced" position on red meat, but whether the evidence clearly identifies intake levels at which colorectal cancer risk increases and whether controlled human trials support plausible mechanisms for that risk. A second issue is whether claims that fibre, vegetables, or an otherwise "healthy diet" can neutralise high red meat intake are actually supported by the mechanistic evidence, or whether they overstate what dietary context can plausibly offset. In this episode, Danny and Alan examine the evidence base by moving beyond the usual epidemiology-only debate. They discuss why regional intake patterns and dose thresholds matter, then explore controlled human feeding studies showing how higher red meat intake can increase endogenous N-nitroso compound formation, faecal water genotoxicity, and other mechanistic biomarkers linked to colorectal carcinogenesis. Timestamps: [01:11] Defining the exposure and outcome [02:34] Carcinogen labels explained [07:54] Epidemiology and dose thresholds [14:04] Interpreting null findings [19:09] Bingham 1996 nitroso study [25:20] Hughes dose response trial [33:49] Cross 2003 heme iron mechanism [42:55] Fecal water genotoxicity [55:42] Tumor mutational signatures [59:38] What we can conclude now [01:04:10] Practical intake recommendations [01:08:41] Key ideas segment (premium-only) Links: Go to episode page (includes links to studies mentioned) Subscribe to Sigma Nutrition Premium Join the Sigma newsletter for free Enroll in the next cohort of our Applied Nutrition Literacy course

External control arms are becoming increasingly important in drug development, but creating valid comparisons requires more than matching patient populations. In this episode, I speak with Ben Ackerman, Director of Real-World Biostatistics at GSK, about one of the most overlooked challenges in external control arm studies: endpoint bias. We discuss why differences in how outcomes are measured can influence study results, what researchers should consider when designing studies, and how the field is evolving to address these challenges. If you work with real-world evidence, causal inference, or innovative clinical trial designs, this episode offers valuable insights into improving the credibility and transparency of external control arm analyses.

Dr. Max Gulhane (MD) is a practising family medicine physician and health-optimising physician with a passion for root-cause analysis of human chronic disease and longevity. We discuss the full solar spectrum and how ultraviolet, visible, blue, red and near-infrared light each affect human physiology, including the POMC pathway, nitric oxide and blood pressure, and the evidence on sunlight, skin cancer and the vitamin D paradox. We discuss how artificial light at night suppresses melatonin and disrupts the circadian control of DNA repair, cardiovascular health, and metabolism. For those interested in light and circadian health, Dr. Gulhane offers a grounded, mechanism-focused framework for aligning daily light exposure with human biology.Full Show Notes here. Thank you to our sponsorDaylight Computer: daylightcomputer.com (code JONATHANJ for $25 off)Dr. Max GulhaneWebsite: https://www.drmaxgulhane.com/Instagram: https://www.instagram.com/maxgulhanemd/X: https://x.com/MaxGulhaneMDYouTube: https://www.youtube.com/@maxgulhanemd/Recommended lectures:Sunlight & Cancer: Beyond Skin Deep — https://youtu.be/SJGvr6dGOgQArtificial Light & Diabetes: No Food Required — https://youtu.be/vgrFpPusSKUWhat Your Cardiologist Doesn't Know About Sunlight & Heart Health — https://youtu.be/NaeqPHEM-d0Jonathan JareckiInstagram: https://www.instagram.com/jonathanjarecki/X: https://x.com/jonathanjareckiNewsletter: https://jonathanjarecki.substack.com/?utm_campaign=profile_chips00:00 Intro03:25 Dr. Max Gulhane04:02 Dr. Gulhane's Love for Science and Medicine09:01 What is Light?12:52 Sunlight Broken Down as a Nutrient14:02 Ultraviolet Light: Sunlight Is More Than Vitamin D15:56 POMC21:38 UVA/UVB on Cardiometabolic Health24:40 Big Picture of UV Light28:41 Sunlight, Skin Cancer, Dermatology Messaging, The Vitamin D Paradox35:10 Blue Light, Artificial Light at Night (ALAN), Mechanisms38:50 Sponsor: Daylight Computer40:34 ALAN, Epidemiology, Cancer, Heart Disease45:04 DNA Repair Mechanisms, Circadian Control47:27 Melanopsin (OPN4), Blue Light, UV Susceptibility53:25 Red, Infrared, Photobiomodulation, Metabolism01:00:08 Blue Light, Metabolism, and the Built Environment01:05:19 Photobiology of Atherosclerosis01:10:11 Blue Light on Cardiovascular Function01:12:25 Three M's of Circadian Health01:18:43 Sunlight, Testosterone, and Reproductive Behavior01:24:14 Support, YouTube, Spotify & Apple Follow, Reviews & Feedback, Social Media, Substack Newsletter#science #sunlight #circadianrhythm

Welcome to this week's Midlife Minute. Today, I'm focusing on all the questions I received about gallbladder health, including HRT-provoking symptoms, supplements that improve gallbladder health, and evidence-based food interventions. IN THIS EPISODE, YOU WILL LEARN: Why the risk of gallstones and gallbladder inflammation increases during the menopause transition How estrogen and progesterone HRT have different effects on gallbladder functioning The differences in risk between transdermal and oral HRT How the progesterone in HRT can cause gallbladder issues in some women What TUDCA is, and how it supports gallbladder health The value of TUDCA for women who have had their gallbladders removed How various nutrients and supplements support bile flow and gallbladder health What can contribute to gallstone formation Connect with Cynthia Thurlow   Follow on X, Instagram & LinkedIn Check out Cynthia's website. Submit your questions to support@cynthiathurlow.com  Join other like-minded women in a supportive, nurturing community: The Midlife Pause/Cynthia Thurlow.  Purchase Cynthia's book, The Menopause Gut. Cynthia's Intermittent Fasting Transformation Book The Midlife Pause Supplement Line Gallbladder Research: Cabrera D, Arab JP, Arrese M. UDCA, NorUDCA, and TUDCA in liver diseases: a review of their mechanisms of action and clinical applications. Seminars in Liver Disease. 2019;39(4):397–404. doi:10.1055/s-0039-1696799  Vang S, Longley K, Steer CJ, Low WC. The unexpected uses of urso- and tauroursodeoxycholic acid in the treatment of non-liver diseases. Global Advances in Health and Medicine. 2014;3(3):58–69. doi:10.7453/gahmj.2014.017  Bai M, Yang L, Liao H, et al. Tauroursodeoxycholic acid improves nonalcoholic fatty liver disease by regulating gut microbiota and bile acid metabolism. Journal of Agricultural and Food Chemistry. 2024;72(41):22655–22668. doi:10.1021/acs.jafc.4c04630  Simon JA, Hudes ES. Relation of serum ascorbic acid to serum vitamin B12, serum ferritin, and kidney stones in US adults. *Archives of Internal Medicine.*1999;159(6):619–624. doi:10.1001/archinte.159.6.619  Walcher T, Haenle MM, Kron M, et al. Vitamin C supplement use may protect against gallstones: an observational study on a randomly selected population. BMC Gastroenterology. 2009;9:74. doi:10.1186/1471-230X-9-74  Tsai CJ, Leitzmann MF, Willett WC, Giovannucci EL. Long-term intake of dietary fiber and decreased risk of cholecystectomy in women. American Journal of Gastroenterology. 2004;99(7):1364–1370. doi:10.1111/j.1572-0241.2004.30281.x  Leitzmann MF, Stampfer MJ, Willett WC, Spiegelman D, Colditz GA, Giovannucci EL. Coffee intake is associated with lower risk of symptomatic gallstone disease in women. Gastroenterology. 2002;123(6):1823–1830. doi:10.1053/gast.2002.37085  Moerman CJ, Smeets FW, Kromhout D. Dietary risk factors for clinically diagnosed gallstones in middle-aged men — a 25-year follow-up study. Annals of Epidemiology. 1994;4(3):248–254. doi:10.1016/1047-2797(94)90099-x Association between dietary magnesium intake and gallstones: the mediating role of atherogenic index of plasma. Lipids in Health and Disease. 2024;23(1):82. doi:10.1186/s12944-024-02074-4  Pitt HA, Doty JE, Murphy MM, Schwarz MB. Progesterone alters biliary flow dynamics. Annals of Surgery. 1999;229(2):205–209. doi:10.1097/00000658-199902000-00008

Katherine MacGilchrist comes from a long line of doctors, has degrees in Pharmacology and Epidemiology and spent many years working in the pharmaceuticals industry. But during ‘Covid' she began questioning the narrative and became a pariah and an outcaste. Since then she has found God, started homesteading and now gives talks to her Somerset community on vaccine dangers and how to deal with them. Her Twitter is @unveildeception ↓ ↓ ↓ ↓ Monetary Metals is providing a true alternative to saving and earning in dollars by making it possible to save AND EARN in gold and silver. Monetary Metals has been paying interest on gold and silver for over 8 years. Right now, accredited investors can earn 12% annual interest on silver, paid in silver in their latest silver bond offering. For example, if you have 1,000 ounces of silver in the deal, you receive 120 ounces of silver interest paid to your account in the first year. Go to the link in the description or head to https://monetary-metals.com/delingpole/ to learn more about how to participate and start earning a return on honest money again with Monetary Metals. ↓ ↓ How environmentalists are killing the planet, destroying the economy and stealing your children's future. In Watermelons, an updated edition of his ground-breaking 2011 book, JD tells the shocking true story of how a handful of political activists, green campaigners, voodoo scientists and psychopathic billionaires teamed up to invent a fake crisis called ‘global warming'. This updated edition includes two new chapters which, like a geo-engineered flood, pour cold water on some of the original's sunny optimism and provide new insights into the diabolical nature of the climate alarmists' sinister master plan. Purchase Watermelons by James Delingpole here: https://jamesdelingpole.co.uk/Shop/ ↓ ↓ ↓ Buy James a Coffee at: https://www.buymeacoffee.com/jamesdelingpole To support independent, no-holds-barred journalism and gain first and full access to all James's content, subscribe directly at https://jamesdelingpole.co.uk x

Mace and Jeff put Matt Walsh's antidepressant episode under the clinical microscope — and it does not pass the functional impairment test. They break down the 2022 Molecular Psychiatry umbrella review that dismantled the low-serotonin narrative, explain why that finding doesn't indict SSRIs as a category, and make the case that the “chemical imbalance” pitch was always more pharmaceutical advertising than clinical science. They also tackle what functional impairment actually means in diagnosis, the gender disparity in antidepressant prescribing, whether the SSRI-to-mass-violence argument is causal or just really committed to showing up in the same sentence, and what clinicians should actually be telling clients about medications they can't fully explain. For anyone who has ever explained serotonin to a client and quietly wondered if they knew what they were talking about: this one's for you. Music: “Machine Heart – Instrumental version” by Icarus. Licensed via Artlist Pro License #JeMO9k. Bielefeldt, A. Ø., Danborg, P. B., & Gøtzsche, P. C. (2016). Precursors to suicidality and violence on antidepressants: systematic review of trials in adult healthy volunteers. Journal of the Royal Society of Medicine, 109(10), 381–392. https://doi.org/10.1177/0141076816666805 Brody, D. J., & Gu, Q. (2020). Antidepressant use among adults: United States, 2015–2018. NCHS Data Brief, No. 377. https://www.cdc.gov/nchs/products/databriefs/db377.htm Chua, K. P., Volerman, A., Zhang, J., Hua, J., & Conti, R. M. (2024). Antidepressant dispensing to US adolescents and young adults: 2016–2022. Pediatrics, 153(3), e2023064245. https://doi.org/10.1542/peds.2023-064245 Healy, D., & Mangin, D. (2024). Post-SSRI sexual dysfunction: barriers to quantifying incidence and prevalence. Epidemiology and Psychiatric Sciences, 33, e44. https://doi.org/10.1017/S2045796024000441 Kuehner, C. (2017). Why is depression more common among women than among men? The Lancet Psychiatry, 4(2), 146–158. https://doi.org/10.1016/S2215-0366(16)30263-2 Moncrieff, J., Cooper, R. E., Stockmann, T., Amendola, S., Hengartner, M. P., & Horowitz, M. A. (2023). The serotonin theory of depression: a systematic umbrella review of the evidence. Molecular Psychiatry, 28, 3243–3256. https://doi.org/10.1038/s41380-022-01661-0 Salk, R. H., Hyde, J. S., & Abramson, L. Y. (2017). Gender differences in depression in representative national samples: Meta-analyses of diagnoses and symptoms. Psychological Bulletin, 143(8), 783–822. https://doi.org/10.1037/bul0000102 Stone, M., Laughren, T., Jones, M. L., Levenson, M., Holland, P. C., Hughes, A., Hammad, T. A., Temple, R., & Rochester, G. (2009). Risk of suicidality in clinical trials of antidepressants in adults: analysis of proprietary data submitted to US Food and Drug Administration. BMJ, 339, b2880. https://doi.org/10.1136/bmj.b2880

The benefits of getting a shingles vaccine seem relatively straightforward: It will prevent you from getting shingles, a painful rash caused by the same virus that causes chickenpox. But researchers have found a surprising link between getting the shingles vaccine and a lower risk of developing dementia. And that's not the only vaccine that seems to have additional benefits. So what's going on here?  To help explain this research are epidemiologist Pascal Geldsetzer, who studies the association between the shingles vaccine and lower rates of dementia; and physician and epidemiologist Helen Chu, who studies the Flu, RSV and COVID-19 viruses. Guests: Dr. Pascal Geldsetzer is an assistant professor of medicine, epidemiology and population health at Stanford University.  Dr. Helen Chu is a professor of epidemiology, allergy and infectious diseases at the University of Washington.  Other episodes you may enjoy: Study Finds COVID mRNA Vaccines Boost Cancer Treatment As Cervical Cancer Deaths Plummet, Experts Credit HPV Vaccine Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that's keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Two disease outbreaks are dominating the news: Ebola in the Democratic Republic of the Congo, and hantavirus, which started spreading on a cruise ship. The U.S. has a one-of-a-kind medical facility that exists just for emergencies like this. It's called the National Quarantine Unit, and it's in Omaha, Nebraska. Right now, 18 Americans from the cruise ship where hantavirus broke out are in quarantine there.  Host Flora Lichtman chats with Angie Vasa, a nurse and administrator who has worked at this emergency center for the last 17 years. They discuss how the facility works, what's happening with the travelers exposed to hantavirus, and how they're preparing for the possibility of Ebola-exposed individuals.   Guest: Angie Vasa is the director of emergency preparedness and special pathogens programs at Nebraska Medicine in Omaha, Nebraska.  Other episodes you may enjoy: Mapping Out How Viruses Jump Between Species How Viruses Have Shaped Our World Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that's keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

On episode #107 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 5/7 – 5/20/26. Host: Daniel Griffin and Sarah Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral FDA Grants Accelerated Approval to Gilead's Hepcludex® (bulevirtide-gmod), the First and Only Approved Treatment for Chronic Hepatitis Delta Virus (HDV) (Gileadl) A Phase 3, Randomized Trial ofBulevirtide in Chronic Hepatitis D(NEJM) Study to Assess Efficacy and Safety of Bulevirtide in Participants With Chronic Hepatitis Delta (CHD) (NLM: ClinicalTrials.gov) Andes Hantavirus Outbreak on a Cruise Ship, 2026 (NEJM) Quick takes: Another hantavirus case, polio in 3 countries, NIAID head steps down (CIDRAP) Dolutegravir Reduces Human T-Cell Lymphotropic Virus Type 1 Proviral Load and Improves Neurological Outcomes in a Phase 2 Controlled Trial (CID) Dolutegravir Appears to Lower Human T-Cell Lymphotropic Virus Type 1 (HTLV-1) Proviral Load: The Emerging Rational Approach to Treatment of HTLV-1–Associated Myelopathy (CID) Use of Dolutegravir for treatment of HTLV-1 (CID) Use of dolutegravir to treat people living with HTLV-1-associated myelopathy (HAM) (CID) Bacterial Urinary Tract Infection (UTI)-free and Recurrent UTI (rUTI)-Free Survivals Following Bladder Electrofulguration in Women With a History of Antibiotic-Refractory rUTI (OFID) Azithromycin for Preschoolers with Wheezing in the Emergency Department (JAMA) Rapid Respiratory Microbiological Point-of-Care Testing and Antibiotic Use in Primary Care (JAMA Internal Medicine) Fungal The Last of US Season 2 (YouTube) Changes in Epidemiology of Candidemia in the United States With a Focus on Candida auris (CID) Parasitic Impact of introducing RTS,S/AS01E malaria vaccine on mortality in young children in Ghana, Kenya, and Malawi: an observational evaluation of a cluster-randomised implementation programme (The LANCET) Ivermectin-Benzimidazole Prescribing Following Celebrity Endorsement  (JAMA Network OPEN) Febrile Temperature Augents Ring-stage Plasmodium falciparum Adhesion to Brain Endothelial Cells (JID) An Increase in Imported Plasmodium vivax Malaria in New York City: Clinical and Demographic Trends Following Recent Migration (OFID) Miscellaneous The State of Physician Leadership (WittkKieffer) Infectious Diseases Fellowship Curriculum: IDSA Training Program Directors Community of Practice (TPDCOP), Curricular and Educational REsources Workgroup (CREW) (CID) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.

The majority of non-fatal gunshot wound survivors walk away with a bullet still inside them. Most are discharged without a removal attempt, without a surveillance plan, and without a conversation about what comes next. This episode fills that gap.Dr. Patrick Georgoff is joined by BIG T co-host Dr. Teddy Puzio (UT Houston), gun violence survivor and trauma surgeon Dr. Madhu Subramanian (Duke), and Dr. Tyler Simpson (Duke ACS Fellow) for a practical, honest conversation about one of trauma's most overlooked topics.What we cover: Epidemiology: how common retained fragments really are, and why the downstream burden is underappreciated When to remove (and when not to): a framework for both index hospitalization and delayed removal Forensic evidence: how to handle bullets in the OR without destroying their evidentiary value — and who to call when you don't know Lead toxicity: the rare but real complication that can surface a decade later, which blood lead levels should prompt action, and when to call hematology or toxicology The psychology: retained bullets are independently associated with depression and reduced return to work — and that belongs in the risk-benefit conversation DOMINATE THE DAYBIG T Trauma Full Series: https://behindtheknife.org/podcast-series/big-t-traumaThis episode of Big T Trauma was sponsored by Teleflex, a global provider of medical devices. Learn more at teleflex.com and at the Teleflex Trauma and Emergency Medicine LinkedIn page. Please visit https://behindtheknife.org to access other high-yield surgical education podcasts, videos and more.  If you liked this episode, check out our recent episodes here: https://behindtheknife.org/listenBehind the Knife Premium: https://behindtheknife.org/premiumOral Board Review: https://behindtheknife.org/oral-boardOral Board Simulator: https://behindtheknife.org/oral-board/simulatorGeneral Surgery Oral Board Review Course: https://behindtheknife.org/premium/general-surgery-oral-board-reviewTrauma Surgery Video Atlas: https://behindtheknife.org/premium/trauma-surgery-video-atlasDominate Surgery: A High-Yield Guide to Your Surgery Clerkship: https://behindtheknife.org/premium/dominate-surgery-a-high-yield-guide-to-your-surgery-clerkshipDominate Surgery for APPs: A High-Yield Guide to Your Surgery Rotation: https://behindtheknife.org/premium/dominate-surgery-for-apps-a-high-yield-guide-to-your-surgery-rotationVascular Surgery Oral Board Review Course: https://behindtheknife.org/premium/vascular-surgery-oral-board-reviewColorectal Surgery Oral Board Review Course: https://behindtheknife.org/premium/colorectal-surgery-oral-board-reviewSurgical Oncology Oral Board Review Course: https://behindtheknife.org/premium/surgical-oncology-oral-board-reviewCardiothoracic Oral Board Review Course: https://behindtheknife.org/premium/cardiothoracic-surgery-oral-board-reviewDownload our App:Apple App Store: https://apps.apple.com/us/app/behind-the-knife/id1672420049Android/Google Play: https://play.google.com/store/apps/details?id=com.btk.app&hl=en_US

On today’s “Closer Look with Rose Scott,” we have an in-depth discussion with the Atlanta Legal Aid Society about a study by Princeton University’s Eviction Lab. It shows Fulton, Cobb, DeKalb, Gwinnett, and Clayton Counties lead the nation in evictions. Those evictions overwhelmingly affected Black households -- more than white, Hispanic, and other racial groups combined. We also speak to Dr. Jodie Guest, Professor and Senior Vice Chair in the Department of Epidemiology at Emory University. The Ebola Virus is spreading quickly through central Africa and has already taken hundreds of lives. We learn more about the nature of the deadly illness and what’s being done to stop it from infecting more people.See omnystudio.com/listener for privacy information.

BUFFALO, NY — May 27, 2026 — A new #research paper was #published in Volume 18 of Aging-US on May 8, 2026, titled “The mediating role of DNA methylation clocks in associations of race, ethnicity, education, income, and occupation with mortality: findings from NHANES 1999-2002.” The study was led by first and corresponding author Hanyang Shen from the Department of Epidemiology and Population Health at Stanford University. In this study, the authors investigated whether DNA methylation aging biomarkers—often called epigenetic aging clocks—may help explain how social inequalities become biologically embedded and contribute to differences in mortality risk. Social factors such as race, ethnicity, educational attainment, household income, and occupation have long been associated with disparities in health outcomes and life expectancy. However, the biological mechanisms linking these social exposures to long-term disease risk and mortality remain incompletely understood. Using nationally representative data from 2,402 adults in the U.S. National Health and Nutrition Examination Survey (NHANES) 1999–2002 linked to mortality follow-up data through 2019, the researchers examined thirteen different DNA methylation biomarkers alongside traditional clinical and behavioral risk factors. The study evaluated whether these epigenetic aging measures mediated associations between social stratification factors and all-cause mortality. The findings showed that several DNA methylation clocks significantly mediated the relationship between social disadvantage and mortality risk. Among all biomarkers examined, GrimAge2 consistently demonstrated the strongest mediation effects, accounting for up to 52% of mortality disparities in some occupational comparisons. DunedinPoAm, a pace-of-aging biomarker, also demonstrated substantial mediation effects across multiple socioeconomic categories. Importantly, the mediation effects observed for several DNA methylation biomarkers frequently exceeded those of traditional clinical risk factors measured in the study, including C-reactive protein and cholesterol-related markers. The results suggest that epigenetic aging measures may capture the cumulative biological effects of multiple social, environmental, behavioral, and physiological stressors simultaneously. “Among all the 13 DNA methylation biomarkers available in NHANES, GrimAge2 consistently exhibited the strongest positive mediation capturing the social disparities on mortality up to 52% (95%CI: 26%-128%), followed by the DunedinPoAm.” Full press release - https://aging-us.net/2026/05/27/dna-methylation-clocks-may-help-explain-how-social-inequality-influences-mortality/ DOI - https://doi.org/10.18632/aging.206377 Corresponding author - Hanyang Shen - hyshen@stanford.edu Abstract video - https://www.youtube.com/watch?v=XObIyirTJok Sign up for free Altmetric alerts about this article - https://aging.altmetric.com/details/email_updates?id=10.18632%2Faging.206377 Keywords - aging, race and ethnicity, social position, epigenetic aging, mediation analysis, mortality disparities To learn more about the journal, please visit https://www.Aging-US.com​​ and connect with us on social media at: Bluesky - https://bsky.app/profile/aging-us.bsky.social ResearchGate - https://www.researchgate.net/journal/Aging-1945-4589 X - https://twitter.com/AgingJrnl Facebook - https://www.facebook.com/AgingUS/ Instagram - https://www.instagram.com/agingjrnl/ LinkedIn - https://www.linkedin.com/company/aging/ Reddit - https://www.reddit.com/user/AgingUS/ Pinterest - https://www.pinterest.com/AgingUS/ YouTube - https://www.youtube.com/@Aging-US Spotify - https://open.spotify.com/show/1X4HQQgegjReaf6Mozn6Mc MEDIA@IMPACTJOURNALS.COM

What does it take for a single idea to travel from a research lab in New Haven to war zones in Uganda, refugee camps in Malaysia, and clinics across 30 countries and six continents? In this episode, we sit down with Dr. Myrna Weissman, one of the most consequential figures in modern psychiatry, to find out.Dr. Weissman co-developed Interpersonal Psychotherapy (IPT) alongside her late husband, Dr. Gerald Klerman, on a simple premise: that human suffering is deeply tied to human connection. Grief. Conflict. Loneliness. Life upended. These are not niche clinical categories, but rather a universal language of distress. And IPT was built to respond to it.In this conversation, Dr. Weissman reflects on five decades of research, the pandemic-era project that became a sweeping global volume (now available free via open access), and what it means to build something that outlives its origins. *This episode briefly mentions suicide.(Re-post: This is one of our most beloved episodes, brought back by popular demand. If you've heard it before, we hope it moves you just as much the second time.)What Is Interpersonal Therapy (IPT) and Why Does It Work?IPT links the emergence of psychiatric symptoms to what is happening in a person's current life. It focuses on four core problem areas:1. Grief — the loss of a loved one2. Disputes — conflict with someone important to you3. Transitions — life changes, even positive ones, that disrupt relationships4. Loneliness/Isolation — chronic or newly developed lack of attachmentThese four areas have proven to resonate across vastly different cultures because they reflect fundamental aspects of the human condition. Dr. Weissman emphasizes that IPT is not the only evidence-based psychotherapy — it is “one tool in the toolbox, not a religion.”IPT for AdolescentsAdolescence is a prime time for IPT's problem areas, especially disputes, transitions, and loneliness. Key takeaways for parents:• Try to understand the specific stressors behind an adolescent's symptoms rather than reacting to global, dramatic statements.• Always be alert to the possibility of suicidal ideation.• Communication barriers between teens and parents are common; a trusted third party (grandparent, therapist, family friend) can sometimes serve as a valuable bridge.The New Book: IPT Around the WorldThis book is now available open access for readers everywhere!The COVID-19 pandemic gave Dr. Weissman the unexpected opportunity to connect with IPT practitioners worldwide. What began as a routine update to the standard IPT manual grew into a sweeping collaborative volume covering more than 30 countries across Africa, Asia, Europe, and the Americas. Contributors were asked: What are you doing? What works? What doesn't? What adaptations did you need to make?Notable chapters include:• Uganda — IPT was introduced around 2003 amid civil war and a mental health crisis. A landmark clinical trial published in JAMA confirmed its effectiveness. Sean Mabry, a former WHO worker, went on to treat hundreds of thousands of people using IPT, even by telephone during the pandemic, and has now established a low-cost program in New Jersey.• China — After government engagement and training by Columbia experts, IPT became what practitioners called a “rapidly growing practice,” with books, training programs, and internet-based delivery.• Malaysia — IPT has been applied with refugees, using the “transitions” framework to help people process displacement and profound loss.• Africa (Ethiopia, Kenya, Mozambique, Senegal, Zambia, Uganda) — Adaptations have been made for cultural context, including how disputes are communicated and resolved within different family and community structures.• Japan and Hong Kong — Initial resistance to psychotherapy has given way to growing acceptance and translated materials.• United States special populations — Chapters cover Alaska Natives, people who are incarcerated, sexual and gender minorities, pre-adolescents, adolescents, and older adults.Cultural AdaptationsDr. Weissman shares a vivid example from Uganda: women in marital disputes are often encouraged not to confront their husbands directly, but to work through an elder who mediates. The underlying IPT principle, that the dispute is driving the symptoms, remains intact; only the implementation changes.Resources Mentioned• International Society of Interpersonal Psychotherapy (ISIPT) — volunteer-run, affordable membership, biannual international conference (10th meeting held in the UK, March 2024)• Dr. Weissman's new book on IPT across international sites — published Open Access, freely available to practitioners and researchers worldwide• Oxford University Press — publisher of the standard IPT manualAbout the GuestDr. Myrna Weissman is the Diana Goldman Kemper Family Professor of Epidemiology and Psychiatry at Columbia University's Vagelos College of Physicians and Surgeons and Mailman School of Public Health, and Chief of the Division of Translational Epidemiology at the New York State Psychiatric Institute. Alongside her late husband, Dr. Gerald Klerman, she co-developed Interpersonal Psychotherapy (IPT), now backed by over 140 clinical trials, translated into numerous languages, and recommended by the World Health Organization.

The ongoing outbreak of hantavirus infections that originated with passengers on the Dutch cruise ship MV Hondius in April has generated concerns across the globe. This very rare occurrence has led to a number of deaths, required quarantining of passengers and prompted emergency responses from public health authorities in multiple countries.  On this episode of Raise the Line from Elsevier, we're tapping the expertise of a leading authority on the subject, Dr. Jamie Childs of Yale University, to provide you with a scientific understanding of hantaviruses and what level of threat is posed by this situation. In short, Dr. Childs believes this is not the start of a pandemic. “The Andes variant involved here is one of the most dangerous hantaviruses, but it is totally controllable with contact tracing.” This timely conversation with host Lindsey Smith is informed by Dr. Childs' decades of hantavirus research as well as learnings from his role leading the CDC's environmental investigation during the landmark 1993 hantavirus outbreak in the Four Corners region of the American Southwest. And be sure to stay tuned to hear his concerns about the factors complicating containment of the current Ebola outbreak in East Africa. Note: this conversation was recorded on May 19th, 2026. Mentioned in this episode: Yale School of Public Health Yale Institute for Global Health If you like this podcast, please share it on your social channels. You can also subscribe to the series and check out all of our episodes at www.osmosis.org/podcast

Carlos Juan Finlay was a Cuban doctor who did a lot of work to understand the spread of Yellow Fever. But Walter Reed got most of the credit. Research: American Experience. “Carlos Finlay (1833-1915).” From The Great Fever. PBS. https://www.pbs.org/wgbh/americanexperience/features/fever-carlos-finlay/ Berenbrok, Dorothy E., "Latin Heritage Month. Carlos Juan Finlay: Outrageous, Courageous and Correct" (2015). Posters: Jefferson History. 3. https://jdc.jefferson.edu/jeffhistoryposters/3 "Carlos Juan Finlay." Encyclopedia of World Biography Online, Gale, 1998. Gale In Context: Opposing Viewpoints, link.gale.com/apps/doc/K1631002194/GPS?u=mlin_n_melpub&sid=bookmark-GPS&xid=bfeecc25. Accessed 29 Apr. 2026. Chaves-Carballo, Enrique. “Carlos J. Finlay: The mosquito man.” Hektoen International. 11/2/2020. https://hekint.org/2020/11/02/carlos-j-finlay-the-mosquito-man/ Corbitt, Duvon C. “Carlos J. Finlay, Cuban Physician.” The Hispanic American Historical Review, Vol. 45, No. 3 (Aug., 1965). Via JSTOR. https://www.jstor.org/stable/2511751 Del Regato, Juan A. “Carlos Juan Finlay (1833-1915).” Journal of Public Health Policy , 2001, Vol. 22, No. 1 (2001). Via JSTOR. https://www.jstor.org/stable/3343556 Faerstein, Eduardoa; Winkelstein, Warren Jrb. Carlos Juan Finlay: Rejected, Respected, and Right. Epidemiology 21(1):p 158, January 2010. | DOI: 10.1097/EDE.0b013e3181c308e0 Ferreira Moreno, Víctor Guillermo. “Evocation to the Dr. Carlos J. Finlay Barres on the centennial of his death.” Colombia medica (Cali, Colombia) vol. 47,1 63-6. 30 Mar. 2016 Finlay, Carlos J. “The Mosquito Hypothetically Considered as the Agent of Transmission of Yellow Fever.” Read before the Royal Academy of Medical, Physical and Natural Sciences Session of August 14th, 1881. https://archive.org/details/b33448541/page/590/mode/1up Finlay, Carlos Juan. “Trabajos selectos del Dr. Carlos J. Finlay. Selected papers of Dr. Carlos J. Finlay.” Habana. 1912. https://archive.org/details/trabajosselectos00finl Finlay, Charles. “Inoculations for Yellow Fever by Means of Contaminated Mosquitoes.” Published in The American Journal of the Medical Sciences, n.s. 102: 264-268, 1891. https://archive.org/details/b33445242/page/n4/mode/1up Finlay, Charles. “Yellow Fever: Its ‘Transmission by Means of the Culex Mosquito.” Published in The American Journal of the Medical Sciences, n.s. 92: 395-409, 1886. https://archive.org/details/b33435698/page/613/mode/1up Palmer, Steven. “A Cuban Scientist Between Empires: Peripheral Vision on Race and Tropical Medicine.” Canadian Journal of Latin American and Caribbean Studies / Revue canadienne desétudes latino-américaines et caraïbes, Vol. 35, No. 69, Special Issue: Landscapes of LatinAmerican Health, 1870-1970. Via JSTOR. https://www.jstor.org/stable/41800498 Spears, Ellen Griffith and Rosa López-Oceguera. “Carlos Juan Finlay, William Gorgas, and Walter Reed and the U.S. Army Yellow Fever Controversy: Competing Historical Memories.” Alabama Review The University of Alabama Press. Volume 74, Number 1, January 2021. https://doi.org/10.1353/ala.2021.0011 Stepan, Nancy. “The Interplay between Socio-Economic Factors and Medical Science: Yellow Fever Research, Cuba and the United States.” Social Studies of Science , Nov., 1978, Vol. 8, No. 4 (Nov., 1978). Via JSTOR. http://www.jstor.com/stable/284817 Thomas Jefferson University. “10 Notable Jefferson Alumni of the Past.” https://library.jefferson.edu/archives/exhibits/notable_alumni/juan_carlos_finlay.cfm Tone, John Lawrence. (2002) “How the mosquito (man) liberated Cuba.” History and Technology, 18:4, 277-308, DOI: 10.1080/07341512.2002.11417735 “Carlos J. Finlay.” 5/16/2023. https://www.unesco.org/en/prizes/carlos-j-finlay/about Woodall, Jack. "Yellow Fever." Infectious Diseases: In Context, edited by Brenda Wilmoth Lerner and K. Lee Lerner, vol. 2, Gale, 2008, pp. 925-931. In Context Series. Gale In Context: Opposing Viewpoints, link.gale.com/apps/doc/CX3045200265/GPS?u=mlin_n_melpub&sid=bookmark-GPS&xid=bf646a26. Accessed 29 Apr. 2026. See omnystudio.com/listener for privacy information.

Spine Health Researcher, Clinician, and Professor, Dr. Christine Goertz shares her life's work in her new book Take Your Back Back. RESEARCH & HEALTH POLICY CAREER I'm Christine Goertz, D.C., Ph.D. I have spent 35 years working with multi-disciplinary teams to conduct research studies and implement best practices designed to optimize care for patients with low back pain. CURRENT ROLE I am a Professor in Musculoskeletal Research at the Duke Clinical Research Institute and Vice Chair for the Implementation of Spine Health Innovation in the Department of Orthopaedic Surgery at Duke University. I am also an Adjunct Professor in the Department of Epidemiology, College of Public Health at the University of Iowa.  WHERE IT ALL BEGAN I received my Doctor of Chiropractic (D.C.) degree from Northwestern Health Sciences University in 1991 and a Ph.D. in Health Services Research, Policy and Administration from the School of Public Health at the University of Minnesota in 1999. ACCOMPLISHMENTS I have extensive experience in the administration of Federal grants, both as a PI and as a program official at the National Institutes of Health (NIH). I have received nearly $45 million in federal funding, as the principal investigator or co-principal investigator, primarily from NIH and the Department of Defense. I have also co-authored more than 135 peer-reviewed scientific papers. MAKING A GLOBAL IMPACT I am honored to have delivered invited lectures, keynote talks, clinical grand rounds, and plenary presentations worldwide. Topics include "Research, Its Not Just for Scientists Anymore," "In Search of the Holy Grail in Low Back Pain Treatment or Anything that Works at All," and " Nonpharmacological Approaches to Pain Management." Venues include the Patient Centered Outcomes Research Institute Annual Meeting, Georgetown University, Duke University School of Medicine, the American Physical Therapy Association's Combined Sections Meeting, the American Chiropractic Association Summit, the World Federation of Chiropractic Research Congress, and the European Chiropractic Union.  Resources: Dr. Goertz's website The Back Pain Chronicles Pain Trainer Take Your Back Back The Cox 8 Table by Haven Medical Find a Back Doctor  

In this episode of PICU Doc on Call, hosts Dr. Monica Gray and Dr. Pradip Kamat discuss a 15-year-old girl who attempted suicide by ingesting rat poison, acetaminophen, ibuprofen, and amlodipine. The episode focuses on long-acting anticoagulant rodenticides (LAARs), such as brodifacoum, which inhibit vitamin K epoxide reductase, causing delayed coagulopathy. Key topics include clinical presentation, diagnostic evaluation, and management, emphasizing vitamin K1 as the primary antidote and prothrombin complex concentrate or fresh-frozen plasma for major bleeding. The patient stabilized with aggressive supportive care, including vasoactive agents and NAC therapy, alongside psychiatric intervention. Listen to learn more!Show HighlightsClinical case of a 15-year-old girl who attempted suicide through polypharmacy ingestionIngestion of multiple substances, including chewable rat poison, acetaminophen, ibuprofen, and amlodipineDiscussion of toxicology related to long-acting anticoagulant rodenticides (LAARs) like brodifacoumSymptoms and clinical presentation following acute ingestion, including metabolic acidosis and elevated lactateDiagnostic evaluation and laboratory findings, including coagulation studies and liver function testsManagement strategies for LAAR poisoning, including the use of vitamin K and supportive careImportance of monitoring for delayed coagulopathy and serial INR testingConsideration of calcium channel blocker toxicity in the context of the patient's clinical instabilityOverview of the mechanisms of action of LAARs and their impact on vitamin K-dependent clotting factorsKey take-home points regarding the recognition and management of rodenticide ingestion in pediatric patientsReferencesReference: King N, Tran MH. Long-Acting Anticoagulant Rodenticide (Superwarfarin) Poisoning: A Review of Its Historical Development, Epidemiology, and Clinical Management. Transfus Med Rev. 2015 Oct;29(4):250-8.Reference 2: Feinstein DL, Akpa BS, Ayee MA, et al. The emerging threat of superwarfarins: history, detection, mechanisms, and countermeasures. Ann N Y Acad Sci. 2016 Jun;1374(1):111-22.

About this episode: A deadly Ebola outbreak in the Democratic Republic of the Congo and Uganda has been declared a global public health emergency by WHO. In this episode: infectious disease epidemiologist Emily Gurley explains why this outbreak is particularly concerning for a region managing existing crises and how public health systems are working to contain transmission and treat patients. Guest: Emily S. Gurley, PhD, MPH, is a professor in Epidemiology at the Johns Hopkins Bloomberg School of Public Health, where she focuses on infectious disease and outbreak investigation. Host: Stephanie Desmon, MA, is a former journalist, author, and the director of public relations and communications for the Johns Hopkins Center for Communication Programs. Show links and related content: WHO declares major outbreak of rare Ebola virus species an international emergency—Science US Imposes Ebola Travel Restrictions as CDC Says Risk Remains Low—Newsweek What else to know: The Ebola outbreak in Central Africa will be challenging to control, but decades of experience will help—The Uptake  Transcript information: Looking for episode transcripts? Open our podcast on the Apple Podcasts app (desktop or mobile) or the Spotify mobile app to access an auto-generated transcript of any episode. Closed captioning is also available for every episode on our YouTube channel. Contact us: Have a question about something you heard? Looking for a transcript? Want to suggest a topic or guest? Contact us via email or visit our website. Follow us: @‌PublicHealthPod on Bluesky @‌PublicHealthPod on Instagram @‌JohnsHopkinsSPH on Facebook @‌PublicHealthOnCall on YouTube Here's our RSS feed Note: These podcasts are a conversation between the participants, and do not represent the position of Johns Hopkins University.

What can a rare hantavirus outbreak on a cruise ship tell us about broader public health risks, and are there warning signs closer to home that we may be overlooking? After a Dutch vessel was linked to the Andes strain, questions emerge about how such diseases spread, what makes them dangerous, and whether other threats, including tick-borne illnesses, are already taking hold. We examine what is known about hantavirus, how it compares to more familiar risks, and what it could signal about shifting patterns in human and environmental health. Dr. Fahad Razak, an internist and epidemiologist at St. Michael's Hospital, looks at the implications for surveillance, preparedness, and public awareness. We then turn to a different kind of signal: the ways animals respond to changing conditions. If animals are constantly communicating, what might humans be missing, and could those observations offer insight into environmental change? Amelia Thomas, journalist and author of "What Sheep Think About the Weather," explores how animals interpret their surroundings, what their behaviours might reveal, and whether learning to pay closer attention could deepen our understanding of the forces shaping both animal and human health.See omnystudio.com/listener for privacy information.

The herbicide paraquat is so toxic it's banned in over 70 countries. But its use in the U.S. is growing, despite known links to Parkinson's disease. In southeastern Mississippi, an industrial plant is leaking tens of thousands of pounds of the chemical into the air. Environmental reporter Delaney Nolan and epidemiologist Beate Ritz join Host Flora Lichtman to discuss the implications of this leak, and what we know about how paraquat affects the body. Guests:  Delaney Nolan is an environmental reporter based in New Orleans. She reported this story for The Lens and the Mississippi River Basin Ag & Water Desk. Dr. Beate Ritz is a professor of epidemiology at UCLA in Los Angeles. Other episodes you may enjoy: Teasing Apart The Causes And Early Signs Of Parkinson's Workout Worms May Reveal New Parkinson's Treatments Want SciFri gear? Check out our new shop! Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that's keeping you up at night? Call us: 877-4-SCIFRI Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Katelyn Jetelina, founder and author of the newsletter Your Local Epidemiologist, talks about what public health authorities do and don't know about the strain of hantavirus on the MV Hondius cruise ship, what the risks are and what the reaction of US-based health officials has signaled about pandemic preparedness here. Photo: Specialist workers in full PPE carry boxes containing hazardous waste as they begin the process of disinfecting the cruise ship MV Hondius after it docked in the Port of Rotterdam following the recent hantavirus outbreak, on May 18, 2026 in Rotterdam, Netherlands. (Photo by Omar Havana/Getty Images) Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

West Side Market updates Cleveland's historic, 114-year-old West Side Market has been undergoing major change in recent years. First, it went through structural change, moving from longtime city management to nonprofit management back in 2024, something that residents and vendors had been calling for for years to improve conditions at the market. Now it's going through a major revitalization, as once the nonprofit team called the Cleveland Public Market Corporation began, it launched a years-long, $70 million transformation project funded in part by the city of Cleveland and City Council, as well as philanthropy and other government sources. But there's still some millions left to raise to complete the vision, and many months left to go until residents see completion of the project. In the meantime, there will be a lot of construction to wade through as you get your groceries and support local vendors. We'll discuss these updates on Tuesday's "Sound of Ideas" and learn what you can expect when you visit the market. Guests: - Rosemary Mudry, Executive Director, Cleveland Public Market Corporation - Don Whitaker, Owner, DW Whitaker Meats & Former President, United West Side Market Tenants Association - Jessy Harb, Co-owner of Harb's Produce What to know about hantavirus More than a dozen American cruise passengers are currently under a 42-day quarantine in Nebraska in a specialized medical facility after spending weeks aboard a ship hit with a deadly hantavirus outbreak that infected at least 11 people, including three who died. Hantavirus is a pathogen that some rodents carry that can sometimes infect humans. The passengers under quarantine are asymptomatic. This incident is harkening memories of another virus that caused a global pandemic six years ago. But health experts say hantavirus is not the same as COVID-19. We'll learn why by talking to a local epidemiologist. Guest: - Tara Smith, Ph.D., Professor of Epidemiology, Kent State University

Allergies have tripled - with hay fever, seasonal allergies, eczema and food intolerances now affecting millions of people. But why are allergy symptoms getting worse, and what does gut health have to do with it? In this episode, Adam Fox, a world-leading allergy Professor at King's College London, explains why allergies may be rising so fast, why many beliefs about allergies are wrong, and what new science reveals about your immune system, skin and gut. Professor Fox explores why some foods are more likely to trigger reactions, and why modern allergy science is increasingly focused on gut health. Adam also discusses why 90% of people told they are allergic to certain things may not actually be allergic, the difference between allergies and intolerances, and why some antihistamines may be doing you more harm than you realise. By the end of this episode, you will have some practical ways to manage hay fever and seasonal allergies, including which antihistamines experts now recommend avoiding, simple ways to reduce pollen exposure at home, and when allergy testing or desensitisation treatment may help. Adam explains how newer treatments are starting to retrain the immune system rather than simply suppress symptoms. If allergies barely existed a few hundred years ago, what changed? And could your gut now be shaping the way your immune system reacts to the world around you?

Chemical exposures in the womb can lead to what biologists call organizational effects - that is, impacts on the developing child that are irreversible. How were developmental problems associated with chemical exposures during pregnancy first discovered? And how did these discoveries influence policy? With me to discuss chemicals and child development is Tracey Woodruff. Tracey is a professor in the Department of Epidemiology and Population Health at Stanford University, where she co-leads the UCSF/Stanford Environmental Research and Translation for Health Center. She is an expert on environmental pollution exposures and impacts on health, with a focus on pregnancy, infancy and childhood, and health equity. Tracey was elected to the National Academy of Medicine in recognition of her pioneering work advancing environmental health and reproductive justice.

A cruise ship, a rare virus, and three dead passengers. It is the headline that has put us all on edge, but how worried should we be about hantavirus? In this episode of The Quicky, we speak with CSIRO Principal Research Scientist Professor Glenn Marsh to find out how this rodent-borne illness spreads, why a specific South American strain has experts concerned and whether Australia is prepared for a potential outbreak.

In a viral confession, Katy Talento — President Trump's former health advisor — revealed her role in keeping Robert F. Kennedy Jr. away from the White House, saying it was her job to “make this problem go away.” “I was a Harvard-trained infectious disease epidemiologist. I believed, religiously, that vaccines were the gold standard of public health interventions,” writes Talento. “Not because I had been shown the evidence for their effectiveness and safety in public health school… but because I had been trained in the orthodoxy of public health, where it was assumed that someone had studied this and it had been demonstrated at some point – so now we could all focus on more pressing matters, like how to get vaccines in more kids' arms around the world.” But slowly, she began to feel suspicious – and her research led her to switch sides. “[S]omething happened in late summer of 2021 – a set of legal contortions between Big Pharma and the FDA that started to make everything painfully clear,” she says in a May 2026 public apology to RFK for her part in keeping him away from the White House. In This Episode: Katy Talento joins Dr. Drew to expose the inner workings of the White House Domestic Policy Council, the DC establishment's efforts to sabotage RFK, and why she no longer trusts the medical consensus. A&E's Flash Shelton explains his unconventional strategies for helping homeowners take back their properties from squatters nationwide. Flash Shelton is the host of A&E's docu-series “Squatters,” which premieres with back-to-back episodes starting Tuesday, May 12th at 10pm and 10:30pm ET/PT. Shelton's journey began in 2019 when squatters took over his mother's vacant home in Northern California. After navigating the eviction process himself, he has gone on to help property owners nationwide in more than 100 cases. Learn more at https://www.aetv.com/ Katy Talento is a licensed health benefits consultant, epidemiologist, and health care reformer. As the top health advisor at the White House Domestic Policy Council, she spearheaded policies on health care pricing, prescription drugs, and the opioid crisis. She earned her graduate degree in Epidemiology from Harvard School of Public Health. She is CEO of AllBetter Health. Follow at https://x.com/katytalento 「 SUPPORT OUR SPONSORS 」 • STRONG CELL – If you want to feel more like your younger self, go to https://strongcell.com/ and use code DREW for 20% off. ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠• FATTY15 – The future of essential fatty acids is here! Strengthen your cells against age-related breakdown with Fatty15. Get 15% off a 90-day Starter Kit Subscription at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://drdrew.com/fatty15⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ • PALEOVALLEY - "Paleovalley has a wide variety of extraordinary products that are both healthful and delicious,” says Dr. Drew. "I am a huge fan of this brand and know you'll love it too!” Get 15% off your first order at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://drdrew.com/paleovalley⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ • THE WELLNESS COMPANY - Counteract harmful spike proteins with TWC's Signature Series Spike Support Formula containing nattokinase and selenium. Learn more about TWC's supplements at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://twc.health/drew⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 「 ABOUT THE SHOW 」 This show is for entertainment and/or informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment. Executive Producers • Kaleb Nation - ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://kalebnation.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ • Susan Pinsky - ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://x.com/firstladyoflove⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Content Producer • Emily Barsh - ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://x.com/emilytvproducer⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Hosted By • Dr. Drew Pinsky - ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://x.com/drdrew⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Learn more about your ad choices. Visit megaphone.fm/adchoices

In Part 2, Nanette K. Wenger examines how underrepresentation in research shaped cardiovascular epidemiology in women. Learn about the impact of key guideline developments, and where critical data gaps remain.  Timestamps:  1:09 – Historical underrepresentation  5:05 – Evidence gaps 

Can faster access to real-world data actually change patient outcomes, or are we still too reliant on controlled clinical trials to see the full picture? In this episode, I sit down with Dr. Alex Asiimwe, Executive Director of Epidemiology at Gilead Sciences, to explore a topic that doesn't get enough attention in the AI conversation, real-world evidence. While much of the industry focuses on AI in drug discovery or diagnostics, Alex brings a different perspective, one rooted in what happens after treatments reach real patients in the real world. As he explains, clinical trials may be the gold standard, but they are still controlled environments. Real-world evidence is where we begin to understand how treatments perform across diverse populations, healthcare systems, and everyday conditions. What stood out in our conversation is just how messy and fragmented that real-world data can be. Much of it is not collected for research purposes, which means it takes months, sometimes up to a year, to clean, structure, and analyze before it can inform decisions. Alex shares how AI is beginning to change that, not by replacing human expertise, but by automating the most time-consuming parts of the process. If that timeline can be cut in half, the impact is immediate. Faster evidence means faster decisions, and in healthcare, delays in evidence can directly affect patient outcomes. We also explore what Alex describes as the "analytics gap," the disconnect between where data exists and where insights are actually generated. Today, much of the evidence used in drug development still comes from limited datasets, often from a single country or region. Yet the treatments themselves are global. That mismatch creates blind spots, particularly in low and middle-income countries where data is often unstructured, fragmented, or simply not accessible. AI has the potential to standardize and unlock that data, helping to create a more complete and representative view of patient populations worldwide. Of course, the challenges are not just technical. Trust, governance, and politics all play a role in whether data can be shared and used effectively. Alex is clear that the biggest barrier is not the science or the analytics, it is building trust between organizations, governments, and communities. Without that, even the most advanced AI models cannot deliver meaningful outcomes. This conversation also touches on the importance of collaboration, not just between healthcare organizations and technology providers like SAS, but across the global ecosystem. Alex highlights how partnerships, open standards, and shared frameworks can help close the analytics gap and accelerate progress in areas like HIV prevention, where understanding real-world patient behavior is critical. As we wrap up, one message comes through clearly. AI is not a miracle solution, and it will not transform healthcare overnight. But when applied to the right parts of the workflow, especially around data preparation and evidence generation, it can create measurable, meaningful change. So as healthcare leaders look to move beyond pilots and into real impact, the question becomes, are we focusing on the right problems, and are we ready to open up the data needed to solve them?  Useful Links Connect with Dr. Alex Asiimwe OHDSI – Observational Health Data Sciences and Informatics Please check our partners of Tech Tech Talks Network Learn more about the NordLayer Browser  

Today, we're diving into a topic that should be getting far more attention: Cardiovascular disease in women. Heart disease is one of the leading causes of death in women—yet it's often under-addressed, oversimplified, and misunderstood in clinical practice. Most women are told: “Eat better. Take this prescription.” But that approach misses something critical. Full citation list:    •    Hall, Kevin D., et al. “Ultra-Processed Diets Cause Excess Calorie Intake and Weight Gain: An Inpatient Randomized Controlled Trial of Ad Libitum Food Intake.” Cell Metabolism, vol. 30, no. 1, 2019, pp. 67–77.e3. Supports the core causal point that ultra-processed foods drive higher intake and weight gain even under controlled feeding conditions; this is not a women-specific lipid paper, but it is the cleanest experimental anchor for why UPFs create a high-throughput metabolic environment.     •    El Khoudary, Samar R., et al. “Menopause Transition and Cardiovascular Disease Risk: Implications for Timing of Early Prevention: A Scientific Statement From the American Heart Association.” Circulation, vol. 142, no. 25, 2020, pp. e506–e532. Supports the midlife women's frame: across the menopause transition, LDL-C and ApoB rise, metabolic risk shifts, and cardiovascular prevention needs to become more deliberate during this window. This supports the “why I care about lipids in endocrine care” part of the episode.     •    Derby, Carol A., et al. “Lipid Changes During the Menopause Transition in Relation to Age and Weight: The Study of Women's Health Across the Nation.” American Journal of Epidemiology, vol. 169, no. 11, 2009, pp. 1352–61. Foundational SWAN paper establishing that the menopause transition itself — not just chronological aging — is associated with adverse lipid shifts in midlife women. This is the original observation that the timing argument rests on.     •    Wu, Bingjie, et al. “Trajectories of Blood Lipids Profile in Midlife Women: Does Menopause Matter?” Journal of the American Heart Association, vol. 12, no. 22, 2023, e030388. Supports the claim that LDL-C, total cholesterol, and ApoB follow distinct trajectory patterns through the menopause transition, with subgroups of women showing rising lipids in the years before the final menstrual period — useful for the timing argument that body and symptom changes can precede the obvious lab story.     •    Matthews, Karen A., et al. “Age at Menopause in Relationship to Lipid Changes and Subclinical Carotid Disease Across 20 Years: Study of Women's Health Across the Nation.” Journal of the American Heart Association, vol. 10, no. 18, 2021, e021362. Supports the point that ApoB and Apo A1 changes cluster around the final menstrual period and that adverse lipid shifts in the early postmenopausal years track with subclinical carotid disease later — connects menopausal timing to the longer cardiovascular arc rather than a one-time lab blip.     •    De Oliveira-Gomes, Diana, et al. “Apolipoprotein B: Bridging the Gap Between Evidence and Clinical Practice.” Circulation, vol. 150, no. 1, 2024, pp. 62–79. Supports the practical ApoB explanation: ApoB reflects atherogenic particle burden and outperforms LDL-C for ASCVD risk prediction in many settings, but adoption lags because clear apoB targets and triggers are still lacking in mainstream guidelines. Good support for the public-service “what the hell is ApoB anyway?” section.     •    Williamson, Laura. “The Slowly Evolving Truth About Heart Disease and Women.” American Heart Association News, 9 Feb. 2024, heart.org/en/news/2024/02/09/the-slowly-evolving-truth-about-heart-disease-and-women. Supports the broader clinical framing that women remain underrecognized or undertreated in cardiovascular care and that women's heart disease still needs better public and clinical communication. This is more public-facing than mechanistic, but useful for your opening frame. Dr. Brendan McCarthy is the founder and Chief Medical Officer of Protea Medical Center in Arizona. With over two decades of experience, he's helped thousands of patients navigate hormonal imbalances using bioidentical HRT, nutrition, and root-cause medicine. He's also taught and mentored other physicians on integrative approaches to hormone therapy, weight loss, fertility, and more. If you're ready to take your health seriously, this podcast is a great place to start.

I'm delighted today to be joined by Dr. Joseph Skelton, professor of Pediatrics, founder and director of Brenner Fit, a program at Wake Forest University School of Medicine. FIT stands for Families in Training, which is a family-based pediatric obesity program. He's the author of a new book on children and their weight, a topic we discussed in a separate podcast. But in this podcast, we're talking about something he teaches at Wake Forest, a course in culinary medicine. This is a fascinating, pioneering area of focus, so let's dig in. Interview Transcript There's a lot of language about medicine and nutrition now, so people talk about food as medicine. There's a move afoot to get more training and nutrition and medical education, and here you are doing culinary medicine. Tell me how all these things differ from one another. Our interest in this here at Wake Forest School Medicine started a little organically with our program. A lot of what we do is focus on family meals. There are decades of research showing the benefits of family meals, not only for the nutrition and obesity risk, but the quality of nutrition, time spent together, parent child communication. Kids are less likely to get pregnant or do drugs and alcohol. All these things from just spending that time together over the meal. And I inherited a small teaching kitchen that was at a local organization that someone before me had gotten funding for. And we, sort of, took it over and used this opportunity to teach families how to cook. And a lot of families know how to cook but trying foods in different ways and to get kids involved and things like that. Then a couple years after that, the local YMCA approached us. They had some space and wanted to do this as a partnership. So I became a fundraising machine for a year or two and took a lot of dinners to raise the funds. And we built this gorgeous teaching kitchen, and we were mainly doing it in the efforts of sort childhood obesity treatment or prevention, getting families, teaching them new recipes, which then kind of extended to that whole key thing of getting families just to be comfortable in the kitchen and spending that time together. And we just started seeing these amazing things. We always say we've converted more kids to Brussels sprouts than I think any other effort of just getting them cooking it a different way. You and I were both probably raised with steamed Brussels sprouts, which I think is an abomination. If you really want to highlight the sulfur smell of a food, then you're going to steam it. And so, we really started to do that. And then students started volunteering. Actually, it was a student, Josh Patman, he's an emergency medicine physician now at East Carolina University, and he was a cook in a professional kitchen college. And he said, hey, could I help volunteer with that? And then more student medical students wanted to do it. And then we all found that you, much like I did, I'm a self-taught cook myself, and the more time you spend in that, the more you learn, the more comfortable you are. And the more you start to know, you know, I can teach med students nutrition all day, but that doesn't teach them how to get nutrition on their patients' plates, into their mouth. And so it really grew from there. And then I, kind of, stumbled upon what other people were doing. It started in New York, but the biggest program started was really Tulane School of Medicine that had it as a very focused way about teaching nutrition through cooking. Not just on a blackboard through PowerPoint slides and stuff like that of like hey, let's teach it in a different way. And the old-fashioned analogy, and actually the medical educators hate this, it used to be see one, do one, teach one. That was sort of the old surgical thing. And so, it's really you got to see how to make a recipe and you got to do it yourself. And what we found that when students start then teaching each other, or teaching patients or teaching community members, it really drives home and gives them a much deeper understanding of what nutrition in the real world is. Let's talk about the need for this. If we go back in time and we think about your parents or my parents, you know, the likelihood is that meals were being prepared from the real foods rather than from a package, let's say, or in a micro. How are things different now for the modern parent that has kept people distanced from their food and where it comes from, and that's led families to be distant because they're not having meals together as much? What does that look like now? Yeah, pulling from our own history, you know, Home Ec is not really a thing anymore. We did this study in our own med students. You know, most of their cooking, nutrition, the nutrition education they're getting tends to be the popular media. They're learning it from social media. Very few students have a degree in nutrition or took a nutrition class. And as much as we have to cram into medical student's education, there's not much room for it. They mainly learn to cook from their families. And what we know is families are cooking less and less for multiple reasons. They're much busier. Especially parents, actually parents of kids of all ages with that. And again, the marketing of food, you know, it's much easier to get ready made meals. And I'm not badmouthing those, you know. We're in talks right now of actually writing a cookbook for families, and one of the things that we promise is we're going to have a chapter on assembled meals. You know, having a pre-made salad with a rotisserie chicken, that's still going to be a better thing to do if you bring that home, sit at a table or at a bar or around a coffee table and eat that meal together. It's still going to be better for your family in multiple ways on multiple levels than eating out. And what I see, it really with families right now when it comes to actually raising "healthy eaters" or raising good eaters is when we... and again, I love a good restaurant, I'm not trying to badmouth that... but when you're going out to eat a lot of kids have endless choices and there's two issues. One is a paradox of choice. Whatever they get, they're always going to think that other thing might have been better. And it doesn't allow them to spread their palate and try different foods and get exposed to different things. And we always laugh... whenever in this field we want to play a drinking game where every time you say complex or complexity, you take a drink because, but it is such a complex issue with parents. You know, with kids and getting meals on the table. And hopefully finding some time, whether it's a breakfast or it's a dinner, but finding that time to come together around a meal. You mentioned the paradox of choice. I was reminded at one point I downloaded this cute app called You Choose or something like that. And it would help you make a decision if you were undecided. It would flip a coin, it would roll a dice. It would do, yes, no, it would do rock, paper, scissors, it would do all these things. And I was at a restaurant once. I couldn't decide between two entrees, so I used it. I did rock, paper, scissors, or something, and I then it said, okay you should choose X. So I ordered X and the second I ordered it, I immediately thought I should have ordered Y. Alright, so tell us about culinary medicine. What does this course look like that you teach? Yeah, the best way to think about it is applied nutrition. Because again, you can understand a ton about nutrition, but if that doesn't change into you getting the foods that you want in front of you, to me it's almost theoretical or scientific. It's applied nutrition. It's this idea of teaching some very basic cooking skills, and then including within that very core elements of nutrition. And for us, we tend to do it by the balanced plate. We think that works really well for families. But having it be very real world. You know, so again, we have recipes... in two weeks, I'm doing one... we're doing a rotisserie chicken and you're breaking it apart and making a chicken salad out of it. We were always teaching using microwavable rice and a couple of the students cornered me and said, this is very offensive to my culture. You need to teach people how to make real rice. But what it looks like for us is about a quarter, almost a third of med students will rotate through these classes. So, it's voluntary. Next year we're actually hopefully going to surpass half of the first-year med school class. That's unbelievable. That's very impressive. Well, especially up until last year I was doing this in my free time and paying for it with fundraising money. But yeah, Wake Forest is really behind this now. But about a quarter to a third of med students. They do five classes. And it's set up and again, that sort of theme of that family meal. They come in and we get stuff cooking. We get stuff in the oven; we get stuff on the stove top. We usually take some time out for a very short lecture. Again, tends to be very practical stuff. We include a lot about social determinants of health and food insecurity. Given what I do, we talk about picky eating. Very little do we go into details about Mediterranean diet and Dash diet and some of the really core things with that. We really just try to keep it about getting that balanced plate of a protein, a starch and a fruit or vegetable on the plate in front of you. They come back and usually finish what they're cooking, and then they sit down to eat together. And unlike when I was in med school and you were in grad school, or when you were teaching, a lot of students don't go to class anymore. A lot of students, they record the lectures so they can listen to them at one and a quarter speed and study in the best way for them. I love getting to know my students on a different level of sitting down. And that's what my really own exposure to medical student education anymore is really through this, which to me is just the ultimate. Being able to sit down, teach them some interesting things, eat a meal with them. Given my chemistry background, I love getting into the science of a lot of the stuff. And I think for them being, you know, sort of STEM kids, it makes a lot more sense. One of my favorite things is the science of grilling, you know, the science of garlic, you know, things like that. And it helps them sort of understand and helps them remember that, and also peppering it with the stories. It just tends to stick that much more when they know the science, they know the story, they know the culture behind it. So, it's five classes. It's all set up that way, that there's a short lecture. They're preparing everything they can and they're eating it. Again, we include some very easy stuff. One of the classes we do microwaveable vegetables because that's what a lot of what their patients are doing. The bagged vegetable medleys. And one, the important thing that we teach them is most of these don't have any seasoning. So yeah, you can microwave them, but you have got to teach your patients throw a bit of olive oil on there, throw a pad of butter, do some salt and pepper, add some other spices to it. And they go nuts with one group will do some more Indian spices. One group will do more sort of traditional, one to do more Asian flavorings to it in our teaching kitchen. It's really teaching very practical things like that. The fun part of that, that's really spun onto the other things that I'll tell you about, is about half of those students that do that- we have about 18 per semester- and about half those students end up volunteering with us. They come to the classes that we have that are community focused. Now some of the students are going through lead teacher training. They get Serve Safe Certified. It's awesome for me and my staff because it saves us a lot of time and overtime that they come in, they let themselves in the kitchen, they set up, they run the class, they clean up, and they can't get enough of it. They absolutely love it. Now you do some celebration of different food cultures in your class. Tell, tell us about that. Including, as I understand, some of the food culture that you grew up with. Yeah. Yeah. That, that's about, that was a big understatement right there. We just love that and that's a great thing. Wake Forest, being a private medical school, kids are from all over the country, from all different backgrounds. And so, we absolutely sort of herald that. One of the things I love doing is class three is a plant-based proteins class. The first class is a general cooking class. The second class has a focus on animal proteins, and again, we're always also cooking vegetables and fruits and starches. The third class is plant-based proteins, and I do that as Southern cooking. And I just love that sort of theme with that. So, we do pinto beans, you know, And the slow cooker. We tell them how to use instant pots, pressure cookers. We do black eyed peas. A lot of these kids don't know that you're supposed to eat that on New Year's Day. I do a vegetarian collard green recipe, taught to me by a local chef. And I think this is probably my number one post that I do in social media is cornbread night. And teaching them how to make cast iron skillet cornbread, which is the only way to do cornbread in my book. And letting them know, sort of, the background of a lot of the stuff. My wife is from South Carolina, so I teach them great thing about cornbread if you're a poor student, is you have a slice with your beans and your collard greens, and then for dessert you put honey on. Which is what I picked up in South Carolina. So, you know, really celebrating that stuff. We have a whole Spanish speaking program, and we have an article written, we just haven't found the right journal for it. It says, leave my tortilla out of this. Instead of, you know, saying, oh, you have to eat less tortillas, celebrate it. Why is that such an important part of not even that culture, but this family's food history and stuff like that. Because food is personal, it's cultural, its family, and it's to be celebrated. We do a fourth-year elective, it's the last full elective of their fourth-year class and a very lucky 20 students get to do that class. And we always have one called Family Night where they bring a dish that's important to them and their family. And it could be like me, it was the roasted chicken that one of my classmates in med school cooked. And I just thought that was so exotic. You know, I never had a whole roasted chicken before. You know, we had a student that had spent the first part of her life in Australia, so she did pavlova and told the history about where the pavlova came from. Now that's considered sort of the national dessert of Australia. And I always remember this one student, he was going to emergency medicine, very quiet kid. And he's over there cooking these porridges. That's the only way I could describe it is just these porridges. We said, what are you doing? And he told the most amazing story. I almost tear up when I talk about it. His grandfather fled Saddam Hussein. He was Iraqi Christian and fled Saddam Hussein and his grandfather lived with them. And this was their afterschool snack. Was this Iraqi dish that his grandfather would make. And there was a sweet one and there was a savory one. And so just stuff like that is... it's fantastic. I just, I can't get enough of that. And they remember that. And so, as students leave us, and I just came from Match Day where they found out where they're spending the next three to seven years of their life. And I always say wherever you're going, learn something about that culture and that food. If you're moving to Cincinnati, you have got to learn about Cincinnati Chili and getta. take something from that. I did all my training in Wisconsin and the Wisconsin supper clubs and how you can tell what a fresh cheese curd is, and it's just... food is fantastic. And we can take that with us wherever we go. And it can give you a way to know your patients even better. And when I hear of a family that they're from West Africa, ah, you like Jollof Rice. And their face lights up and like, oh yeah, where'd you have Jollof rice? So, it's a great way to get to know more about people. So, there's way more to it than cooking technique. I mean, there's, you know, you roast a chicken that this temperature for that long, or here's how long you microwave. It's really a lot more than that, isn't it? It's just like medicine. It's science and an art. And you know that one of my most popular lectures I give does not have to do with obesity but has to do with barbecue and all the different styles of barbecue. And what is just amazing, despite what we know about the science of taking spareribs, which are an incredibly tough cut of meat, and you have to cook them low and slow to get that temperature up. I think it's 189 degrees or higher where you start to get the collagen that breaks down and they turn tender. So yeah, spareribs to be good tender and edible, you're talking four to six hours. But then you go to Tuscaloosa, Alabama and you go to Dreamland Barbecue. They do spareribs over live coals for an hour and a half. I sat there talking to the person doing it. I'm like, you must bake them ahead of time. Do you soak them? And he's just like, nope. And so again, I know the science of that. So how do these jokers do that for an hour and a half, and it turns out in what my opinion are the greatest bear ribs in the world. Oh really? Oh, I'll have to try. I'll have to try that place out. Yeah, there's several. Birmingham has two there. There's several in Southeast and they cook them for an hour and a half. Over live coals. Violating every scientific principle of low and slow. Don't get it. It's fascinating. That sounds really good. Yeah. Well, Joey, thanks very much. One final question. Do you see this... is this a movement in medicine now or more and more people doing this? Yeah, you know, it was really big for a while. Tulane had so much. You know, they were sharing their curriculum and they were doing some good research. And that's where a lot of what you see now as the food is medicine food is medicine or as medicine where hey, we need to find ways to get medically tailored meals in the patient's hands. There's really good evidence of that with diabetes and stuff like that. I think what you're seeing now is, I think especially with some of our efforts in the government right now, is sort of demanding more nutrition education in medical school. And I'm going to double down on culinary medicine because you know what? My students, myself, I don't need to know more about the biochemistry of carbohydrates. I need to know the biochemistry of cooking and how to do that quickly and safely to teach my patients. And also, with that, we have to forget, there's an entire field that's already doing this, you know? Dietetics and nutrition and there's professionals that probably are way better than us. But I think having this increased understanding, especially dwelling in that food space, is going to help us relate to them that much more. So even though I do a lot of nutritional counseling and talking, I still use my dieticians way more. I think they're going to be way better at that. So I think there is a lot of steam building towards that, but we don't need to turn doctors into junior dieticians. But I think we can give them deeper understanding of how food and nutrition affects their health and the broader aspects of that. It's not about the biochemistry of insulin secretion, it's about where are they accessing food and how can they make use of the food pantry near them. And let them know, hey, it's okay when you open a can of beans it's gonna smell like cat food initially, but you know what? You wash that off and actually it's not going taste like cat food. And you know, just kind of be able to work with them. Hey, canned beans are perfectly fine. Guess what? Canned beans now are coming in no salt added and low salt preparations. And here's an easy way that you could take these canned great northern beans, chop up some herbs with olive oil and a chunk of garlic and you can make some fantastic bean recipe that is incredibly filling and healthy and cheap as dirt. Oh, that's really nice. Well, this is an exciting advance in the field and you're really at the forefront of it, and your students are lucky that they have this available to them. So, thanks very much for being with us and sharing your experience. Well and what the big secret about this is, Kelly, is this is fantastic. I love doing it. Our med school really values it, but it's a lot of fun. That's the thing. You can tell just by the way you're talking about it. It is so much fun. And again, I just saw all my students that were graduating. And that some of these I hadn't seen in three years and they're like doing Doctors in the Kitchen and then seeing patients, they're cooking and being able to relate to them in those ways. I just have a text from one of my students going to family medicine, and she's like, this changed the trajectory in my career. And I'm not taking credit for that, but just the idea of giving that experience I think especially in my world to medical students, I absolutely love it. In the end it's a hell of a lot of fun. BIO Joseph A. "Joey" Skelton, MD, MS, FAAP, FTOS, DABOM is a Professor of Pediatrics, and of Epidemiology and Prevention, at Wake Forest University School of Medicine. He is the Founder and Director of Brenner FIT® (Families In Training), an interdisciplinary pediatric obesity treatment, prevention, research, and educational program. He serves as the Director of the Center for Prevention Science in Child and Family Health, Vice Chair of Research for the Department of Pediatrics, Associate Leader of Community and Stakeholder Engagement at Wake Forest University School of Medicine. He is the Editor-in-Chief of the journal Childhood Obesity. He is board certified in Pediatrics and Obesity Medicine. His research and clinical work has focused on the treatment of children with obesity. He has secured nearly $10 million in funding over the past 15 years, has given over 50 national and international presentations, and has over 130 peer-reviewed publications. He enjoys teaching cooking classes that are both fun and informative to anyone who will listen.

“Violence has been misdiagnosed. And there's a misdiagnosis that has caused us to not be able to control it as we could.” — Dr. Gary Slutkin Human violence appears ubiquitous. In Iran. In Gaza. In Ukraine. In Sudan. In American cities and homes. So widespread, indeed, that it seems naturally hardwired into us. Our species-being, so to speak. But, for Dr. Gary Slutkin, there is nothing inevitable about human violence. Slutkin — an epidemiologist who spent years fighting cholera, tuberculosis, and AIDS in Africa before focusing his medical mind on violence — argues that violence is neither a character flaw nor a moral failing. Rather than being baked into our natures, Slutkin sees violence as a contagious disease. It meets the clinical definition of a plague, he says. The more violent our homes, communities, media, politics, the more virally it spreads. Slutkin's new book, The End of Violence: Eliminating the World's Most Dangerous Epidemic, makes the case that violence has been misdiagnosed for centuries. We analyse it as a crime problem, a character problem, an inter-state problem. So we punish, incarcerate and bomb. But none of these approaches confront the contagion. This can only be done, Slutkin argues, with what he calls “violence interrupters” — people from within the infected community who find the most at-risk individuals and cool things down before they escalate. Communities that have applied this approach have seen reductions in violence of 40 to 70 percent, Slutkin boasts, with Cherry Hill, one of Chicago's most dangerous neighbourhoods, experiencing 450 days without a shooting. There will be a time, he promises, when the plague of human violence will be mostly overcome. I hope Dr. Slutkin is correct. But suspect that his brave new violence-free world, like Huxley's, might be simultaneously utopian and dystopian. Five Takeaways •       Violence Meets the Clinical Definition of a Contagious Disease: Slutkin is not speaking metaphorically. Violence meets the definition of a disease: characteristic signs and symptoms causing morbidity and mortality. It meets the definition of contagious: it causes more of itself. One violent event leads to another — in a home, in a community, in a region, in a war. The more you are exposed to it, the more likely you are to do it. This is the same mechanism as measles, as cholera, as COVID. Susceptibility varies — for violence, it has to do with how much you feel humiliated, how much social pain you carry, how much grievance a leader has taught you to feel. But the operating system is the same. •       Violence Has Been Misdiagnosed: For centuries, we have treated violence as a moral failing: a matter of bad people making bad choices. The response has been punishment, incarceration, war. None of these interrupt the contagion. In fact, incarceration concentrates the infection. The misdiagnosis has cost millions of lives. The correct diagnosis — epidemic disease spreading through exposure — changes everything. You don't blame a cholera patient for drinking contaminated water. You don't punish a COVID patient for breathing. You interrupt the spread. You treat the susceptibility. You cool it down. •       Violence Interrupters: The Epidemic Control Playbook: Cure Violence Global trains and deploys violence interrupters: people from the same community, who speak the same language, who have often been involved in violence themselves. Their job is to find the most at-risk individuals — the ones most likely to shoot or be shot next — and intervene before the next event. The approach works. Communities that have applied it have seen reductions of 40 to 70 percent. Over a dozen American cities are at fifty- or sixty-year historic lows. Cherry Hill in Chicago went 450 days without a shooting. Baltimore, New York, and other cities have had similar results. •       Authoritarian Violence Disorder: Chapter eight of The End of Violence is called “Infections of the State.” Slutkin's argument: authoritarian leadership is itself a form of epidemic violence. It spreads violence outward into its own population — through ICE raids, through threats, through the approval and scripting of violence by others. It also spreads it abroad, through war. Violence doesn't know borders. The mechanism is the same: exposure increases transmission; grievance and humiliation increase susceptibility. Trump's Iran war is not just a war. It is authoritarianism causing war. And the spread doesn't stop at the border. •       Uganda Dropped HIV 85 Percent with Behavior Change Alone: In 1987, Slutkin arrived in Uganda, then the most infected country in the world, where a third of the population had what was then a 100 percent lethal disease. Using the epidemic control playbook — no medicines, just behaviour change interventions — they dropped the rate 85 percent. The same approach drove down Ebola, drove down TB long before medication existed. Slutkin's point: we do not need pharmacological intervention to eliminate violence. We need the right people doing the right interventions with the right understanding of how contagion works. We have done it. We can do it again. About the Guest Dr. Gary Slutkin is an epidemiologist and the founder and CEO of Cure Violence Global. He is the author of The End of Violence: Eliminating the World's Most Dangerous Epidemic (Health Communications, Inc., 2026). He is a Professor of Epidemiology and Global Health at the University of Illinois Chicago and a former WHO epidemiologist. References: •       The End of Violence: Eliminating the World's Most Dangerous Epidemic by Gary Slutkin (2026). •       Cure Violence Global — Slutkin's organisation. cvg.org. •       Episode 2887: Steven J. Ross on The Secret War Against Hate — the historical companion on American violence and authoritarian disorder. About Keen On America Nobody asks more awkward questions than the Anglo-American writer and filmmaker Andrew Keen. In Keen On America, Andrew brings his pointed Transatlantic wit to making sense of the United States — hosting daily interviews about the history and future of this now venerable Republic. With nearly 2,900 episodes since the show launched on TechCrunch in 2010, Keen On America is the most prolific intellectual interview show in the history of podcasting. WebsiteSubstackYouTubeApple PodcastsSpotify 

Episode 201, Jay Cutler & Manager Matt bring on Dr Zach Pallikaros from the UK. Dr. Zach is a competitive bodybuilder, has a PhD in Epidemiology and is the owner of Pumping Iron Gym in london! Also making an appearance is Dave Bourlet from JayCutler TV! TRT Kingdom - https://trtkingdom.com/?ref=cutlercast Cutler Nutrition - http://jaycutler.com/cutlercast  

What if one of the most popular health trends in the world, fasting, is actually being done wrong by millions of people? In this powerful and deeply grounded conversation, Darin sits down with world-renowned longevity expert Dr. Valter Longo to cut through the noise surrounding fasting, dieting, and modern health trends. From the dangers of prolonged fasting and skipping breakfast to the science behind the Fasting Mimicking Diet, this episode delivers a reality check rooted in decades of clinical research, not social media hype. They explore the intersection of longevity, cancer, metabolism, and modern lifestyle, unpacking why extreme protocols fail, why simplicity wins, and why aligning with your biology is the true key to a long, disease-free life.     What You'll Learn Why most fasting trends are misapplied and potentially harmful The safest and most sustainable fasting window for longevity Why skipping breakfast is linked to increased mortality risk The science behind the Fasting Mimicking Diet (FMD) How fasting impacts cancer cells vs healthy cells The hidden risks of GLP-1 weight loss drugs Why "easy solutions" often lead to worse long-term outcomes The importance of circadian rhythm in metabolism The truth about protein intake and long-term health risks Why slow, consistent change beats every "quick fix"     Chapters 00:00:00 – Opening: SuperLife mission and framing the conversation 00:00:32 – Sponsor: Therasage infrared sauna and heat therapy benefits 00:03:16 – Introduction: Dr. Valter Longo and longevity research 00:03:40 – The fasting craze: what's misunderstood 00:04:05 – Documentary discussion: science vs entertainment 00:05:13 – Why education must outweigh entertainment 00:06:19 – The danger of social media health advice 00:07:00 – Food systems, pharma, and systemic health issues 00:07:58 – Why clinical trials matter more than anecdotes 00:08:15 – Framing fasting: trends vs real science 00:08:59 – The problem with DIY fasting 00:10:03 – The safest fast: 12-hour daily fasting explained 00:10:38 – Risks of long fasting: cholesterol, gallstones, mortality 00:11:09 – Why skipping breakfast increases health risks 00:11:49 – 12-hour fasting as the most sustainable protocol 00:12:13 – Modern eating habits: 15+ hour eating windows 00:12:34 – Why extreme diets fail long-term 00:13:37 – Feasibility: why most people won't sustain extremes 00:13:56 – Introducing the Fasting Mimicking Diet (FMD) 00:14:53 – Risks of fasting without personalization 00:15:20 – Why fasting can do more harm than good 00:15:45 – Sponsor: Alkemis Paint, indoor toxicity and non-toxic paint 00:18:42 – Clinical trials: meal timing and metabolic health 00:19:03 – Morning vs evening calorie intake study 00:19:56 – Why late eating disrupts metabolism and sleep 00:20:21 – Epidemiology: skipping breakfast increases mortality 00:21:18 – Circadian rhythm and digestion explained 00:22:11 – Evolutionary biology of eating patterns 00:22:41 – Circadian violations and long-term consequences 00:23:11 – Short-term benefits vs long-term risks 00:24:01 – Why slow progress leads to real results 00:24:49 – Realistic timelines: years, not weeks 00:25:19 – The modern system pushing unhealthy behaviors 00:25:48 – GLP-1 drugs: convenience vs consequences 00:26:13 – The danger of "effortless health" 00:27:13 – Exercise analogy: why effort still matters 00:28:06 – The "pill for everything" mentality 00:28:48 – Finding balance between extremes 00:29:25 – Sponsor: Our Place, non-toxic cookware and health 00:31:12 – Personalization vs one-size-fits-all health 00:31:51 – GLP-1 risks: depression, anxiety, muscle loss 00:32:36 – Natural vs drug-induced weight loss differences 00:33:29 – Rebound weight gain and hormonal suppression 00:34:14 – Supplements vs fixing root causes 00:34:37 – What is the Fasting Mimicking Diet 00:35:05 – Cancer research: fasting and treatment synergy 00:36:13 – How FMD mimics fasting while protecting the body 00:37:06 – Gut health and microbiome benefits 00:38:32 – FMD vs water-only fasting outcomes 00:39:26 – Clinical trials: Crohn's and colitis remission 00:40:03 – Importance of independent research 00:41:20 – Longevity through the lens of fatherhood 00:42:23 – Concerns about AI and children's development 00:43:25 – Social isolation vs digital addiction 00:44:25 – The need for balance in technology use 00:45:10 – AI overdependence and cognitive decline 00:46:18 – Mental health crisis and modern technology 00:47:10 – Reclaiming creativity and human agency 00:48:43 – Fasting and cancer: immune system activation 00:49:53 – Why cancer cells resist fasting signals 00:51:10 – The "desert analogy" for cancer vulnerability 00:52:54 – Combining fasting with therapies 00:54:07 – Future of treatment: precision targeting 00:55:14 – Early detection and personalized interventions 00:56:12 – Where fasting fits in cancer care today 00:57:31 – The protein debate: how much is too much 00:58:17 – Protein intake guidelines explained 00:59:07 – Quality vs quantity of protein 01:00:18 – SuperLife Patreon and accessing exclusive content 01:01:21 – The protein obsession problem 01:02:00 – Children consuming excessive protein 01:03:18 – Portion control and dietary awareness 01:04:07 – Risks of excessive protein intake 01:05:04 – Minimal benefits vs long-term risks 01:06:12 – Longevity populations and low protein intake 01:08:00 – The future of nutrition science 01:12:00 – Final reflections on longevity and health 01:15:00 – Closing thoughts: aligning with biology     Thank You to Our Sponsors Therasage: Go to www.therasage.com and use code DARIN20 at checkout for 20% off Alkemis: Go to alkemispaint.com and use code DARIN10 for 10% off your order. Our Place: Toxic-free, durable cookware that supports healthy cooking. Use code DARIN for 10% off at fromourplace.com.     Join the SuperLife Community Get Darin's deeper wellness breakdowns — beyond social media restrictions: Weekly voice notes Ingredient deep dives Wellness challenges Energy + consciousness tools Community accountability Extended episodes Join for $7.49/month → https://patreon.com/darinolien     Find More from Dr. Valter Longo Website: valterlongo.com Instagram: @prof_valterlongo Get His New Book: Fasting Cancer     Find More from Darin Olien: Instagram: @darinolien Podcast: SuperLife Podcast Website: superlife.com Book: Fatal Conveniences New Show: Roadmap to Happiness     Key Takeaway "The path to longevity isn't found in extreme protocols or quick fixes, it's found in consistency, alignment, and understanding your biology. When you stop chasing shortcuts and start working with your body instead of against it, that's when real transformation happens, not just in how long you live, but in how well you live."

"The rates of fractures are highest in the high milk drinking countries, basically North America, Scandinavia, Denmark, and they're lowest in countries that actually don't consume milk at all." Today, we're joined by one of the most influential and widely cited figures in nutrition science. Dr. Walter Willett, Professor of Epidemiology and Nutrition at the Harvard T.H. Chan School of Public Health, has published over 2,000 papers across four decades. His work includes some of the largest and most rigorous studies on diet and chronic disease ever conducted. He is the author of several books, including the bestselling Eat, Drink, and Be Healthy, which challenged prevailing nutrition dogma and offered a clearer, evidence-based path forward. In this conversation, we examine the eating patterns most closely linked to longevity—for both human health and the health of the planet—the rise of foods designed for convenience rather than nourishment, and the risks they pose. We also break down the practical steps that offer the greatest protection against illness. So tune in for the rare opportunity to hear from a scientist and physician whose work continues to define the boundaries of nutrition. What we discuss: The potential risks of dairy consumption during adolescence in relation to bone health. Dairy-free sources of calcium and how to meet needs without milk. Concerns with current dietary guidelines and how they may mislead the public. Why plant protein sources are preferable to animal sources. The Planetary Health Diet and what it emphasizes. How diet influences susceptibility to infectious diseases, especially in children. The types of processed foods most harmful to health. The primary drivers of the obesity epidemic. Practical tips for eating healthier with limited access to fresh foods. Key principles to follow when navigating conflicting nutrition advice.  Resources: Walter C. Willett | Harvard T.H. Chan School of Public Health The Nutrition Source Eat, Drink, and Be Healthy: The Harvard Medical School Guide to Healthy Eating 1 Million Tables Click the link below to learn about the FISCAL Act https://switch4good.org/fiscal-act/ Share the website and get your resources here https://kidsandmilk.org/ Dairy-Free Swaps Guide: Easy Anti-Inflammatory Meals, Recipes, and Tips https://switch4good.org/dairy-free-swaps-guide SUPPORT SWITCH4GOOD https://switch4good.org/support-us/ ★☆★ JOIN OUR PRIVATE FACEBOOK GROUP ★☆★  https://www.facebook.com/groups/podcastchat ★☆★ SWITCH4GOOD WEBSITE ★☆★ https://switch4good.org/ ★☆★ ONLINE STORE ★☆★ https://shop.switch4good.org/shop/ ★☆★ FOLLOW US ON INSTAGRAM ★☆★ https://www.instagram.com/Switch4Good/ ★☆★ LIKE US ON FACEBOOK ★☆★ https://www.facebook.com/Switch4Good/ ★☆★ AMAZON STORE ★☆★ https://www.amazon.com/shop/switch4good

Dr. Tesha Monteith talks with Ayesha Sohail about her abstract titled "Global Burden of Headache Disorders in Older Adults (Aged ≥ 55 Years) from 1990-2021: An Analysis of Epidemiology, Trends, and Socioeconomic Disparities."  Read more about this abstract on the AAN website. 

We learn about a new injectable microgel to help reduce bleeding in infants who require surgical care. In a mice model, it reduced bleeding by at least 50%. Ashley Brown, Professor of Biomedical Engineering at North Carolina State University and UNC Chapel Hill tells presenter Claudia Hammond more about this new material her team has designed.Joined by Professor of Global Health and Epidemiology at Boston University in the US, Dr Matthew Fox, Claudia hears about a mystery illness that is being investigated by health officials in Burundi, which has caused five deaths and sickened thirty-five people. So far lab analysis of the illness - which causes fever, vomiting, and diarrhoea - has been negative for Ebola and Marburg viruses, Rift Valley fever, and others.We hear about influential analysis from Cochrane which has concluded that "breakthrough" Alzheimer's drugs are unlikely to benefit patients. Researchers said the impact was "well below" what was needed to make a difference to dementia patients' lives. However, their report has also provoked a vicious backlash from equally esteemed scientists who label it as fundamentally flawed.We're joined by health journalist Katie Silver in Mexico, who brings us the news that the President, Claudia Sheinbaum, has announced the details of a plan to introduce universal healthcare – no mean feat in country of 130 million people.And we hear about an experiment that was done by academics to see if they could trick AI chatbots into believing in an entirely fake disease. Presenter: Claudia Hammond Producer: Jonathan Blackwell

This isn't just another interview. I sat down with Dr. Stuart McGill to talk honestly about back pain, training, and all the stuff people get wrong online. We get into flexion, pain science, injuries, and how to actually train without messing yourself up long term. No fluff, no internet arguments, just a real conversation. If you train, deal with pain, or coach others, you'll get something from this.   00:00 – Introduction and Overview 03:11 – Addressing Criticisms and Flexion 10:46 – Epidemiology and Risk Assessment 14:04 – Core Endurance and Spine Hygiene 18:58 – Coaching and Performance Nuance 21:40 – Adaptation and Tissue Science 33:02 – Mechanisms of Disc Resolution 36:07 – Case Studies in Strength and MMA 44:49 – Refining the Assessment Process 50:25 – Neuroscience vs. Biomechanics 55:29 – Reintroducing Load and Progressive Training 01:00:37 – Future Directions and Closing   https://chrisduffin.com/ Coaching, Peptides, Supplements, eBooks & Merch, Education, and my Free Community! A deeper dive on coaching, peptides, and regenerative amplification method at https://www.enhancedexecutive.com/  

Yale epidemiologist Dr. Harvey Risch digs into PubMed's controversial retraction of a 2025 study of Fenbendazole (FenBen) for cancer treatment by Dr. William Makis. Naomi Wolf Ph.D. is concerned about bizarre cloud formations and the real threat of government geoengineering programs – and the exclusion of women from public prayer spaces. Evolutionary biologist and pseudoscience expert Massimo Pigliucci breaks down the ancient practices of Stoicism and Epicureanism, explaining the biological and societal forces that lock human beings into predictable routines. Naomi Wolf, Ph.D. is an independent journalist, co-founder, and CEO of DailyClout.io. She edits The Pfizer Papers and authored Facing the Beast and War Room / DailyClout Pfizer Documents Analysis Volunteers' Reports eBook. More at https://x.com/naomirwolf and https://naomiwolf.substack.com⠀Massimo Pigliucci, PhD, is the K.D. Irani Professor of Philosophy at the City College of New York. His academic work is in evolutionary biology, philosophy of science, the nature of pseudoscience, and practical philosophy. He has a PhD in Evolutionary Biology from the University of Connecticut and a PhD in Philosophy from the University of Tennessee. He has published over 190 technical papers in science and philosophy and is the author or editor of 23 books. Learn more at https://massimopigliucci.net/⠀Dr. Harvey Risch is Professor Emeritus of Epidemiology at Yale. He provided testimony to the US Senate regarding the COVID-19 pandemic and has spoken widely about his opposition to masking, vaccine mandates, and the reliability of PCR tests – along with his research on COVID prevention and treatment with existing drugs. In 2025, President Trump appointed him to chair the President's Cancer Panel. Follow at https://x.com/DrHarveyRisch 「 SUPPORT OUR SPONSORS 」 • STRONG CELL – If you want to feel more like your younger self, go to https://strongcell.com/ and use code DREW for 20% off. • AUGUSTA PRECIOUS METALS – Thousands of Americans are moving portions of their retirement into physical gold & silver. Learn more in this 3-minute report from our friends at Augusta Precious Metals: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://drdrew.com/gold⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ or text DREW to 35052 ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠• FATTY15 – The future of essential fatty acids is here! Strengthen your cells against age-related breakdown with Fatty15. Get 15% off a 90-day Starter Kit Subscription at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://drdrew.com/fatty15⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ • PALEOVALLEY - "Paleovalley has a wide variety of extraordinary products that are both healthful and delicious,” says Dr. Drew. "I am a huge fan of this brand and know you'll love it too!” Get 15% off your first order at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://drdrew.com/paleovalley⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ • THE WELLNESS COMPANY - Counteract harmful spike proteins with TWC's Signature Series Spike Support Formula containing nattokinase and selenium. Learn more about TWC's supplements at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://twc.health/drew⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 「 ABOUT THE SHOW 」 This show is for entertainment and/or informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment. Executive Producers • Kaleb Nation - ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://kalebnation.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ • Susan Pinsky - ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://x.com/firstladyoflove⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Content Producer • Emily Barsh - ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://x.com/emilytvproducer⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Hosted By • Dr. Drew Pinsky - ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://x.com/drdrew⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Learn more about your ad choices. Visit megaphone.fm/adchoices

Bird flu has flown off the national news radar, with only scattered, local reports of dead birds in parks and poultry farms. Is it simply no longer a concern, or have cuts to federal science funding disrupted monitoring for this disease? Airborne pathogens expert Seema Lakdawala gives a flyover view on where bird flu stands today, and whether the government's current monitoring efforts are enough to help prevent another pandemic. Guest: Dr. Seema Lakdawala is co-director of the Center for Transmission of Airborne Pathogens and an associate professor at Emory University in Atlanta, Georgia. Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.

 If you lose a spouse, you're a widow. If you lose your parents, an orphan. But we don't have the language for someone who lost a sibling – your first friend, your first ally, your first enemy (probably, at least temporarily). Grief always feels like a gut punch, but losing a sibling is a unique kind of pain that we don't talk about enough.  So today, I'm joined by Steph Wittels Wachs, former TTFA guest and sister of comedy legend Harris Wittels, who died in 2015 of an accidental overdose. We're talking about what losing a sibling means and sharing the notes, advice and insights from people who know what it's like to live in the world without their siblings. Cited in this episode: Rogne, S., Grotta, A., Liu, C., Berg, L., Saarela, J., Kawachi, I., Hiyoshi, A., & Rostila, M. (2025). All-cause mortality around the anniversary of a sibling's death: findings from Swedish National Register Data. AMERICAN JOURNAL OF EPIDEMIOLOGY. https://doi.org/10.1093/aje/kwaf213  Tatjana Gazibara, Katherine A Ornstein, Christina Gillezeau, Melissa Aldridge, Mogens Groenvold, Merete Nordentoft, Lau Caspar Thygesen, Bereavement Among Adult Siblings: An Examination of Health Services Utilization and Mental Health Outcomes, American Journal of Epidemiology, Volume 190, Issue 12, December 2021, Pages 2571–2581, https://doi.org/10.1093/aje/kwab212  Davidson, D. (2018). Sibling loss - disenfranchised grief and forgotten mourners. Bereavement Care, 37(3), 124–130. https://doi.org/10.1080/02682621.2018.1535882   Herberman Mash, H. B., Fullerton, C. S., & Ursano, R. J. (2013). Complicated Grief and Bereavement in Young Adults Following Close Friend and Sibling Loss. Depression & Anxiety (1091-4269), 30(12), 1202–1210. https://doi.org/10.1002/da.22068     Watch us on YouTube here! Get this episode ad-free here! Listen to Geoffrey's album on Spotify and Apple! LINKS TO RELATED EPISODES! https://feelingsand.co/podcasts/terrible-thanks-for-asking/86-sundays/  https://feelingsand.co/podcasts/terrible-thanks-for-asking/what-does-all-this-loss-mean/  Don't you want someone to take care of you?  _ Right now, go to Quince.com/TFA for free shipping and 365-day returns. That's a full year to wear it and love it. And you will. Now available in Canada, too. Don't keep settling for clothes that don't last. Go to Quince.com/TFA for free shipping and 365-day returns. Quince.com/TFA Shop my favorite bras and underwear at SKIMS.com. After you place your order, be sure to let them know we sent you! Select podcast in the survey and be sure to select our show in the dropdown menu that follows. Right now, our listeners get an additional 15% off any annual membership at MASTERCLASS.com/TFA. That's 15% off at MASTERCLASS.com/TFA. With evening and weekend course options, Fordham's online MSW lets you keep working while earning your degree, completing the program in as few as 16 months. Learn more and apply at fordham.edu/TTFA. Learn more about your ad choices. Visit megaphone.fm/adchoices