Science Friday

There's been wave after wave of bad news about the ocean: warming temperatures, overfishing, acidification, coral bleaching. But in the last few years, there have also been some big wins for the big blue—as well as a narrative shift, in which the ocean itself has almost become its own larger-than-life character in conservation conversations. So how should we think about the future of the seas? And how do the stories we tell about the ocean shape how we think about it? Flora chats with marine biologist Helen Scales, author of “What the Wild Sea Can Be,” which is the Science Friday book club pick for September and October. Check out the SciFri Book Club to read along. Read an excerpt from “What the Wild Sea Can Be: The Future of the World's Ocean.” Guest: Dr. Helen Scales is a marine biologist and author of several books, including “What the Wild Sea Can Be: The Future of the World's Ocean.” Transcript will be available after the show airs on sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that's keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

When humans finally land on Mars, what should they do? A report from the National Academies of Sciences, Engineering, and Medicine lays out the science objectives for a crewed Mars mission. In January, planetary scientist Lindy Elkins-Tanton, who co-chaired the report committee, joined Host Flora Lichtman to talk about the plans to send people to Mars. We also get an update on the mission to survey the asteroid Psyche. Elkins-Tanton tells us how she managed the team that made the Psyche mission possible, and what she learned from her mistakes. Guest: Dr. Lindy Elkins-Tanton is a planetary scientist. She's the head of NASA's Psyche mission and director of UC Berkeley's Space Sciences Laboratory. Transcript will be available after the show airs on sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that's keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

AI is popping up in many corners of society, but how are doctors using it in their practice? We asked our physician listeners to call in, and many of you did. What we heard mirrored broad trends: that more and more doctors are using AI tools for diagnosis, paperwork, and getting up to speed on patients. But they also have concerns. So how is AI changing medical care? And how is it affecting patients? Joining Host Flora Lichtman to sort fact from hallucination is physician-computer scientist Jonathan Chen, who's studied the accuracy of these models and how healthcare workers use them. Guest: Dr. Jonathan Chen is an associate professor of medicine and director for Medical Education in Artificial Intelligence at Stanford University. Transcript will be available after the show airs on sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that's keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

We've been hearing for years that climate change makes weather more extreme, and extreme weather more frequent. But what's been more difficult to measure is exactly how climate change influences a particular weather event. For example, how much more intense was Hurricane Lala because of climate change? How much more deadly were India's heat waves this summer? A growing field called attribution science is trying to answer questions like these. Flora chats with climate scientist Joyce Kimutai about the field and why it's so important. Then, we hear from climate law expert Maxine Burkett about how attribution science could be used in policy, and in the courtroom, to hold emitters responsible. Guests: Dr. Joyce Kimutai is a climate scientist specializing in attribution science. She works for the World Weather Attribution Consortium at Imperial College London and is the principal climate scientist for the Kenya Meteorological Services. Maxine Burkett is a professor of climate, environment, and society at Stanford University in California. Transcript will be available after the show airs on sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that's keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

GPS is such an essential part of our lives that it's easy to forget there was once a world without it. But, like many tech advancements of the 20th century, GPS was originally created by the U.S. military. So how did it become a part of daily civilian life? And how vulnerable is it to manipulation? Katherine Dunn has written all about this and more in her book, “Little Blue Dot: How GPS Shaped the Modern World.” Guest: Katherine Dunn is a science journalist and author of “Little Blue Dot: How GPS Shaped the Modern World.” Transcript will be available after the show airs on sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that's keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

A controversial pipeline project in Michigan has been stuck in legal limbo for years. But this month, the Michigan Supreme Court sided with environmentalists and leaned on an ancient legal framework: the public trust doctrine. This doctrine, which dates back to the Roman Empire, says that natural resources, like water, belong to the public, and development must do no harm. Legal experts say this argument is cropping up more and more in climate and environmental lawsuits. Joining Flora to get into the details are environment reporter Vivian La, and law professor Oday Salim. Guests: Vivian La is the climate solutions reporter for Interlochen Public Radio and Grist in Northern Michigan. Oday Salim is director of the Environmental Law & Sustainability Clinic and a co-director of the Environmental and Energy Law Program at the University of Michigan Law School. Transcript will be available after the show airs on sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that's keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

When the James Webb Space Telescope started sending back images in 2022, something mysterious appeared: little red dots, speckled across the sky. They didn't look like any known celestial objects, and astronomers began racing to figure out what they were. There was a lot of hot debate, but researchers are making progress—the dots appear to be black holes, but black holes like we've never seen them before. In a recent study, astrophysicist Rohan Naidu and his team looked into one little red dot with the catchy name of MoM-BH*-1 and concluded it was a new cosmic category called a black hole star. Guest: Dr. Rohan Naidu is an assistant professor at the Institute for Astronomy at the University of Hawaiʻi. Transcripts for each segment will be available the week after the show airs on sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that's keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

In the new movie “The End Of Oak Street,” bits of a suburban Michigan neighborhood get sucked back through time to a prehistoric world of dinosaurs. It made us wonder, aside from the danger of getting snacked on by an allosaurus, what other challenges would modern humans face in that ancient world? Flora talks with paleontologist Steve Brusatte about the conditions of the late Cretaceous era. Guest: Dr. Steve Brusatte is a paleontologist and author of “The Story of Birds: A New History from their Dinosaur Origins to the Present.” Transcript will be available after the show airs on sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that's keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Microplastics have been documented throughout the human body, including the reproductive system. But the field of microplastics research is very new, and it's not yet clear if, or how, these tiny particles affect our health. Producer Kathleen Davis has been reporting on the handful of scientists trying to uncover what microplastics mean for pregnancy and fetal development. She joins Host Flora Lichtman to debrief what she's learned. Read the full story here. This story was produced with the assistance of the Journalism & Women Symposium (JAWS) Health Journalism Fellowship, supported by The Commonwealth Fund. Guests: Kathleen Davis is an audio producer for Science Friday based in New York. Dr. Phoebe Stapleton is a toxicologist and microplastics researcher at Rutgers University in New Jersey. Transcript will be available after the show airs on sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that's keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

When you think of physics, your mind might go to forces—like gravity, friction, and magnetism—or to astrophysics, like galaxies and exoplanets. But many of the same principles used to understand how the universe works can also be used to study Earth's climate systems. At its core, climate change is a physics problem. But traditionally, research institutions have kept climate science and physics separate. Morgan O'Neill has spent her career with one foot in the classical physics world and the other in climate change research. Now she's on a mission to invite more traditional physicists into the field of climate science. She speaks with Ira about the overlaps between the two fields and why more physicists should join in on climate research. Guest: Dr. Morgan O'Neill is an assistant professor at the University of Toronto and chair of the American Physical Society's group on the physics of climate. Transcript will be available after the show airs on sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that's keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

When you ask an LLM like ChatGPT or Claude a question, the model goes through its massive amount of training data and guesses the answer by mathematically predicting the word most likely to appear next in a sentence. This model, experts say, will not work well for technology designed to navigate the physical world. Something like a robot that works in a warehouse will instead require a “world model” that can understand spatial surroundings, like the stuff we walk by or bang into. But what is a world model, exactly? And how do you train AI to recognize what the real world looks like? Host Ira Flatow checks in with tech journalist Joanna Stern, who's seen the early days of these models up close, even in her own home. Then, we check in on the math world, where frontier AI models have made meaningful progress on decades-old problems. Mathematician Emily Riehl gives us the big picture on how significant these results actually are. Guests: Joanna Stern is a tech journalist who writes newsletters and creates videos for New Things Media. Dr. Emily Riehl is a professor of mathematics at Johns Hopkins University. Transcript will be available after the show airs on sciencefriday.com.   Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that's keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Watching a loved one with Alzheimer's or dementia slowly lose their cognitive abilities can be heartbreaking. While the person you once knew seems to be slipping away, sometimes people with Alzheimer's briefly seem like their old selves again. They may remember a long-forgotten name or suddenly regain the ability to have a fluid conversation. What do these moments of lucidity really mean for the progression of the disease? And what implications do they have for those living with the disease, and their caretakers? Alzheimer's researcher Andrea Gilmore-Bykovskyi talks to Ira about these questions and more. Guest: Dr. Andrea Gilmore-Bykovskyi is an associate professor of emergency medicine, and co-director of the Lucidity in Alzheimer's and Dementia (LEAD) Network at the University of Wisconsin-Madison. Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that's keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Winter in Colorado looked very different this year. Many parts of the state experienced record-high temperatures and record-low snowpack, which had downstream effects on farming, sports, tourism, and more. For those economies and livelihoods that rely on snow, what happens when snow becomes unreliable? And can we prepare for it? Producer Kathleen Davis speaks with Halle Zander, news director at Aspen Public Radio, about how this is playing out in Aspen. Then, environmental historian Mike Childers talks us through how Colorado's economies may need to adjust. Guests: Halle Zander is the news director at Aspen Public Radio. Dr. Mike Childers is an associate professor of environmental history at Colorado State University in Fort Collins. Transcript will be available after the show airs on sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that's keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

The earth is facing a biodiversity crisis, and there's a lot of attention on species that are threatened, or at risk of dying out completely. But, there's another critter category that's a little more mysterious: species that are “lost to science.” This means scientists aren't quite sure how many of them there are out there—or if there are any left at all. Producer Kathleen Davis talks to biologist Matt Forister, who is so dedicated to finding more information about these lost species that he created a whole scientific journal about them. Plus, 28 of the 178 firefly species in the United States and Canada are currently lost to science, according to the community science project Firefly Atlas. We're joined by firefly researcher Candace Fallon, who is working to confirm which firefly butts are still blinking and which have burnt out. Want to help find fireflies near you? Find out how to participate in the Firefly Atlas. Guests: Dr. Matt Foristor is a professor of biology at the University of Nevada-Reno and editor-in-chief of the Journal of Lost Species. Candace Fallon is a senior endangered species conservation biologist at the Xerces Society for Invertebrate Conservation. Transcripts for each segment will be available the week after the show airs on sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that's keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

President Trump has signed an executive order calling for a change to the childhood vaccination schedule. Specifically, he wants to separate the MMR vaccine, which protects against measles, mumps, and rubella, into three separate shots. There's no scientific research to indicate that these changes would be beneficial, and the order has sparked backlash from medical associations and drug manufacturers.  Meanwhile, over 2,400 people have contracted measles in the United States so far this year, topping the total number of cases for 2025 in just seven months. And with vaccination rates declining, there's a lot of conversation about what's driving vaccine hesitancy and how to combat misinformation.   Elisabeth Marnik has lived in both worlds: She wasn't vaccinated as a kid because her parents were concerned that vaccines could do harm. In high school, she fell in love with science. She went to college, got vaccinated, and then earned a PhD in immunology. She joins Flora to talk about what people misunderstand vaccine hesitancy, and how she approaches science communication in today's messy information ecosystem. Guest: Dr. Elisabeth Marnik is an immunologist and the executive director of The Evidence Collective. Transcripts for each segment will be available the week after the show airs on sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that's keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

In a lab in the Rocky Mountains, a group of scientists is hard at work trying to find answers across biology, physics, and engineering: They're looking into things like the hydrodynamics of insect pee and the physics of sheepdog herding, and working to designing robots that resemble squid and hearing aids that only cost a dollar. These endeavors may seem unrelated, but they're glued together by bioengineer Saad Bhamla's philosophy of science driven by curiosity, and how to make the most of the lab's time. He joins Host Flora Lichtman to talk about what led him to this approach. Guest: Dr. Saad Bhamla is an associate professor of chemical and biomolecular engineering at the University of Colorado Boulder. Transcripts for each episode are available within 1-3 days at sciencefriday.com.   Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that's keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Human childbirth is often difficult and incredibly painful—just ask anyone who's been through it. And for a long time, childbirth seemed to be uniquely difficult for humans. But a new study suggests that we aren't alone: Some small primates birth offspring whose heads are nearly twice the size of the mother's pelvic area.   So how do those primates go through difficult childbirths? Why didn't evolution make ours any easier? And what can this tell us about humankind? Flora explores these questions and more with anthropologist Lia Betti. Guest: Dr. Lia Betti is an associate professor of anthropology at University College London in the UK. Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that's keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Former Interior Secretary Deb Haaland, a member of the Laguna Pueblo tribe, was the first Native person to hold a cabinet position. Now she's running to be governor of New Mexico.  Haaland joins Host Flora Lichtman to talk about her new memoir, “A Voice Like Mine,” her time at the Interior Department, and why she thinks lawsuits are a good thing when it comes to the environment.  Read an excerpt from “A Voice Like Mine.” Guest: Deb Haaland served as Secretary of the Interior under President Biden. She is a member of Laguna Pueblo tribe and lives in Albuquerque, New Mexico. Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that's keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Keeping your butt in a seat for hours a day increases the risk of heart attacks, diabetes, psychiatric conditions, and more. But in our tech-filled world, many of us lead sedentary lives, whether because of school, work, or leisure. Researchers set up an experiment to see how much movement would make a difference for people who spend their days at a desk—and 23,000 people signed up. Joining Flora to tell us what they found is tech journalist Manoush Zomorodi, author of “Body Electric: The Hidden Health Costs of the Digital Age and New Science to Reclaim Your Well-Being.” Read an excerpt of “Body Electric.” Guest:  Manoush Zomorodi is host of NPR's TED Radio Hour and author of “Body Electric: The Hidden Health Costs of the Digital Age and New Science to Reclaim Your Well-Being.” Other episodes you may enjoy: 8.5 Hours Of Daily Sitting Linked To Higher BMI And Cholesterol How Is Screen Time Affecting My Kid? The transcript for this episode is available at sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that's keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Dr. Masao Tomonaga was only 2 years old when the United States bombed his home city of Nagasaki. He survived, and grew up to become a physician for other survivors, known as hibakusha. He also studied hematology, and his research on leukemia and myelodysplastic syndromes was foundational for understanding how radiation affects the body.  In August 2025, the 80th anniversary of the bombings of Hiroshima and Nagasaki, he spoke with Host Ira Flatow about his life's work, how hibakusha lived with the medical consequences of the bombs, and his message to the world. Guest:  Dr. Masao Tomonaga is a survivor of the atomic bombing of Nagasaki and director emeritus of the Japanese Red Cross Nagasaki Atomic Bomb Hospital. Other episodes you may enjoy: House Stalls On Bill To Compensate Victims Of Nuclear Testing Revisiting The Nuclear Age With ‘Oppenheimer' The transcript for this episode is available at sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that's keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Imagine you wanted to get a general idea of what people are eating in a given community. You could look at grocery store sales, or do surveys, but neither can capture a complete picture.  Microbiome researcher Lawrence David and his lab look to another source of data: genetic material in sewage water. It turns out that detectable DNA signatures of individual plant and animal species remain behind even after they've been eaten, digested, excreted, and flushed down the toilet. He joins Host Flora Lichtman to describe his “Edible Atlas” project, the backend limitations of sewage analysis, and where the research might go.  Guest:  Dr. Lawrence David is an associate professor of molecular genetics and microbiology in the Center for Genomics and Computational Biology. He runs the Edible Atlas project at Duke University. Other episodes you may enjoy: You Share Your Gut Microbiome With Your Friends Dirty Diapers Reveal How Germy Babies' Microbiomes Are The transcript for this episode is available at sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that's keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

"Is this the real life? Is this just fantasy? Caught in a landslide, no escape from reality. Open your eyes, look up to the skies and see." There's something about space that captures the imagination of scientists and artists alike. Just ask astrophysicist Derek Ward-Thompson and astronomer Brian May (yes, THAT Brian May, guitarist of Queen). In their book "Islands in Infinity: Galaxies 3-D," they turn flat images of the galaxies to three dimensional spacescapes that leap off the page. In March, Host Flora Lichtman spoke with Ward-Thompson and May about the enchanting nature of space and the collision of art and astronomy. And yes, they get into the music. Guests:  Dr. Brian May is an astronomer and the guitarist of Queen. Dr. Derek Ward-Thompson is an astrophysicist at the University of Lancashire in England. Other episodes you may enjoy: Investigating ‘Flow State' With The Bassist From Phish New Telescope Captures The Cosmos In Groundbreaking Detail The transcript for this episode is available at sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that's keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

In nature, enzymes are the catalysts that make much of biology work. They jumpstart chemical reactions that either wouldn't happen, or would happen super slowly. They break down food, build other molecules, extract energy, and more. What if we could harness evolution to engineer designer enzymes that do other specific jobs that benefit us?  Putting that idea into practice changed the game for chemistry, and earned Frances Arnold the Nobel Prize prize in 2018. She called it “directed evolution.” Today, thousands of labs use her methods to coax enzymes into doing things no one ever thought of. She joined Host Flora Lichtman in March 2026 to talk about where she sees this approach going in the future, and the personal evolution that brought her into science. Guest:  Dr. Frances Arnold is the Linus Pauling Professor of Chemical Engineering, Bioengineering and Biochemistry at the California Institute of Technology in Pasadena, California. Other episodes you may enjoy: Enzymes Are Taking On Our Plastic Problem Even Nobel Prize Winners Deal With Imposter Syndrome The transcript for this episode is available at sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that's keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Brain cancers are rare, but devastating. Patients face short life expectancies after diagnosis. Brain tumors are often impossible to remove completely. And radiation and chemotherapy don't always stop them from spreading.  It's a daunting class of disease to study, but that didn't dissuade Michelle Monje from trying. She has spent two decades studying how brain tumors form and interact with healthy brain cells, and pioneered the field of cancer neuroscience.  Guest: Dr. Michelle Monje is a professor of pediatric neuro-oncology at Stanford Medicine.  Other episodes you may enjoy: Promising new treatments for pancreatic cancer and ALS The new frontier of cancer research is in space Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that's keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Astronaut food is not known as a frontier of culinary imagination, unless you count rehydrated shrimp cocktail. As NASA prepares for longer trips to the moon and Mars, is space cuisine ready for an overhaul?  Flora speaks with retired astronaut Clayton Anderson, who spent 167 days in space, and chef David Skinner, who has advised NASA on how to make food for astronauts better.  Guests: Clayton Anderson spent 15 years as a NASA astronaut, with stints on the International Space Station in 2007 and 2010. He's currently based in Nebraska. David Skinner is the executive chef and owner of Eculent and Ishtia, two Houston restaurants. He's advised NASA on how to make food for astronauts better. Other episodes you may enjoy: Mission Orbital Eats: Engineer Foods For Extreme Environments Making A Meal Fit For An Astronaut Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that's keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

At one point this year, the 50 hottest cities on the planet were all in one country: India. The average peak temperature in those cities was 112 F. India is one of the most climate vulnerable countries in the world, and weather disasters, such as heat waves, have become more extreme and more common in recent years.  So how is this extreme heat affecting people in India? And what needs to change to keep people safe? Flora speaks with Gulrez Azhar, a physician and researcher who has spent much of his career studying the health impacts of heat waves in India.   Guest: Dr. Gulrez Azhar is a physician and researcher studying the health impacts of heat waves in India.  Other episodes you may enjoy: The Alarming Impacts Of Extreme Heat Extreme Heat Is Making Learning—And Teaching—More Difficult Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that's keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

About 130 days a year, a research vessel leaves Miami and sets out to catch, measure, sample, tag, and release sharks in Florida's coastal waters. Over the course of a year, they'll encounter about 600 animals in a process called “fisheries independent monitoring,” an effort to gather data on sea creatures that isn't skewed by changes in fishing procedures, equipment, or regulations.  Marine conservation biologist Catherine Macdonald leads the lab behind that effort. She joins Host Flora Lichtman to talk about shark conservation, share stories from her research, and spread shark joy.  Guest: Dr. Catherine Macdonald is a marine conservation biologist and director of the Shark Research and Conservation Program, part of the Rosenstiel School of Marine, Atmospheric, and Earth Science at the University of Miami. Other episodes you may enjoy: What Greenland Sharks Are Teaching Us About Aging Eyes Fishing For—And Saving—Sharks off the Jersey Shore Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that's keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

During the early Cold War era, the United States Army and later the NSA began recruiting and training codebreakers and intelligence officers to decipher intercepted Soviet messages. Among those recruits were a group of highly skilled Black women who were employed as cryptologists to decode these messages. But their role in Cold War intelligence operations has been largely overlooked, until now. Host Flora Lichtman talks with historian Sarah Valentine about her book, “Decoding the Devil: Black Women Codebreakers and the Secret War Against Stalin's Bomb.” Read an excerpt of “Decoding the Devil.” Guest: Dr. Sarah Valentine is the author of “Decoding the Devil: Black Women Codebreakers and the Secret War Against Stalin's Bomb.” Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that's keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

The tropical waters of Sri Lanka, an island off the coast of India, are home to a population of blue whales unlike any other. These whales stay put, while every other known population migrates. That discovery was made by budding scientist Asha de Vos more than 20 years ago—it made a splash, and so did she. She later became the first Sri Lankan to earn a PhD studying marine mammals, charting a new scientific path in her country. De Vos joined Host Flora Lichtman in 2025 to discuss her path into science, what it means to be the first in her field, and how she built a marine biology program from the ground up. Guest: Dr. Asha de Vos is a marine biologist and the founder and executive director of the non-profit Oceanswell. She's based in Sri Lanka. Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that's keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

In the last couple months, Vermont, Alabama, and Oklahoma have passed data privacy laws. Massachusetts is negotiating its own version. Meanwhile, congressional lawmakers have introduced national privacy bills that would preempt these state laws. In light of all this legislation, we're revisiting an interview from February about how the United States' data ecosystem makes it possible for any number of government agencies and businesses to buy our private data, from facial scans to health records to location tracking. Host Flora Lichtman talks with law professor and tech policy expert Laura Moy, who has testified in Congress about privacy laws and how data brokers profit off of personal data. Guest: Laura Moy is an associate professor of law at Georgetown Law, based in Washington, D.C. Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that's keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

In 2020, Andrea Ghez shared the Nobel Prize for her observations of a supermassive compact object at the center of the Milky Way galaxy—an object that has all the hallmarks of a supermassive black hole. Ghez had developed techniques that allowed her to peer through galactic dust clouds with the Keck telescopes and observe the movements of stars orbiting the galactic center. Measuring their velocity and orbits provided information about the galactic core. She joins Host Flora Lichtman to talk about this game-changing discovery, what we've learned about the galactic center, and her own orbit in science.  Guest: Dr. Andrea Ghez is a Nobel Laureate in Physics (2020) and a professor of physics & astronomy at UCLA. Other episodes you may enjoy: The Monster At The Heart Of The Milky Way A Mysterious Gas Is Discovered In The Milky Way Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that's keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Back in May, a paper published in Nature Sustainability reignited a decades-old debate about coastal Louisiana: Should people leave? Climate researchers wrote that due to rising sea levels, coastal Louisiana has crossed the point of no return and that governments should be making plans now for places like New Orleans to relocate. Jessica Dandridge-Smith, who runs The Water Collaborative in New Orleans, speaks with Flora about why this paper sparked such a strong reaction, and how she thinks about the possibility of relocation. Then, we chat with climate scientist A.R. Siders about how we can plan for the future while taking care of our communities in the present. Guests: Jessica Dandridge-Smith is the executive director of The Water Collaborative of Greater New Orleans. Dr. A.R. Siders is an associate professor at the University of Delaware studying climate adaptations.  Other episodes you may enjoy: In Louisiana, A Chance To Study A Successful, Growing Wetland Save The Wetlands, Save The World Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that's keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Pompeii is known for its disastrous end with the eruption of Mount Vesuvius, but for archeologists, what came before is just as interesting. Researchers are using artifacts left behind in the remarkably well-preserved Roman city to piece together what life was like for the thousands of people who lived there 2,000 years ago.  A new book and television show analyze some of these clues to tell the stories of the ordinary people who faced this extraordinary event. Flora speaks with archaeobotanist Jess Venner, author of “The Lost Voices of Pompeii,” and actor Tom Hiddleston, host of National Geographic's “Pompeii: Out of Time with Tom Hiddleston.” Read an excerpt from “The Lost Voices of Pompeii: Life and Death on Pompeii's Final Day” Watch the interview on YouTube. Guests: Dr. Jess Venner is an archaeobotanist at the University of Oxford and author of “The Lost Voices of Pompeii.” Tom Hiddleston is an actor and producer, and host of National Geographic's “Pompeii: Out of Time with Tom Hiddleston.” Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that's keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

An outbreak of the foodborne illness cyclosporiasis has sent thousands of people running to the bathroom this summer. Health officials have linked the outbreak to lettuce served at Taco Bell locations in five states, but there are still a lot of unanswered questions. Food safety expert Byron Chaves joins Flora to talk about the “explosive” nature of the illness and why pinpointing a source of the parasite has been so difficult. Guest: Dr. Byron Chaves is an associate extension specialist and professor in the Department of Food Science at Rutgers University in New Jersey.  Other episodes you may enjoy: How does a tick bite cause a red meat allergy? Use of herbicide linked to Parkinson's is on the rise in the US Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that's keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

The Nancy Grace Roman Space Telescope is scheduled for an early launch at the end of August. It will rest about a million miles from Earth at Lagrange point 2, where forces of gravity and motion balance out, allowing it to orbit the sun in sync with the Earth. The Roman Telescope is designed to collect masses of data that could inform questions about dark energy, dark matter, and exoplanets. Jackie Townsend, project manager for the mission, joins Host Flora Lichtman to discuss the telescope's backstory, and what scientists hope it will do. Then, turning from deep space to deep oceans, Anthony Tarantino of the Woods Hole Oceanographic Institution joins Flora to describe the recent maintenance and recertification process for the famous Alvin deep-sea submersible. It's more than an oil change: The process involves disassembling the vehicle down to the bare frame.  Guests: Jackie Townsend is project manager for the Nancy Grace Roman Space Telescope mission. She's based at NASA's Goddard Space Flight Center.  Anthony Tarantino is program manager for the Alvin Group at the Woods Hole Oceanographic Institution. Other episodes you may enjoy: Mars Rover, Move Over: Making A Rover To Explore The Deep Sea Listening for the cosmic ‘dark ages,' from the lunar far side Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that's keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

For two decades, a perplexing illness has been spreading: After a lone-star tick bite, people find themselves with a severe allergic reaction to red meat. The CDC estimates up to 450,000 people in the U.S. may be affected with alpha-gal syndrome, up from just a few dozen documented cases in 2009. New research finds that in some states, more than 30% of people are positive for alpha-gal antibodies—but not all of them have the syndrome. Flora speaks with allergist Scott Commins, who has studied alpha-gal syndrome for nearly 20 years, to unpack this finding and next frontiers for treatment. Guest: Dr. Scott Commins is the William J. Yount Distinguished Professor of Medicine and associate chief for allergy and immunology at the UNC School of Medicine in Chapel Hill, North Carolina.  Other episodes you may enjoy: Instead Of A Vaccine For Lyme, How About A Vaccine For Ticks? Why Don't We Have A Vaccine For Lyme Disease? Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that's keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

One of the most irresistible questions in sci-fi stories about aliens is what our reaction will be when we learn of their existence. Horror? Bewilderment? Relief? Euphoria? It's a scenario we love to imagine again and again, like in Steven Spielberg's recent movie, “Disclosure Day.” But how would humanity react if we learned of intelligent aliens? Can you actually study that? It turns out there's a whole lab inside SETI, the Search for Extraterrestrial Intelligence, that is thinking about what the public response might be and how to prepare for it. Host Ira Flatow sits down with astronomer Lucian Walkowicz and philosopher-ethicist Chelsea Haramia, co-directors SETI's Discovery and Futures Lab, to talk about the research that's been done to answer these questions. Guests: Dr. Lucian Walkowicz is an astronomer and science advisory board member at SETI. Dr. Chelsea Haramia is a senior research fellow at the University of Bonn in Germany, and a philosopher-ethicist at SETI. Other episodes you may enjoy: How Close Are We To Answers About Aliens? The Human Obsession With Aliens Goes Way, Way Back Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that's keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Dino Martins has plucked maggots out of a dead elephant, pulled botflies out of camel snot, and willingly let a horsefly feast on him. Why? Because he's obsessed with parasites. Dino is an entomologist who grew up in rural Kenya, and he's worked all over the world studying how insects keep this planet alive. And along the way, he met some of the world's most iconic freeloaders, which he describes in his new book, “Hidden Creatures: Luscious Leeches, Bashful Botflies, and the Wondrous, History-Shaping World of Parasites.” Flora speaks with Dino about his unlikely journey into science, the beauty and disgust of parasites, and why these little moochers deserve more of our care. Read an excerpt from “Hidden Creatures: Luscious Leeches, Bashful Botflies, and the Wondrous, History-Shaping World of Parasites.” Guest: Dr. Dino Martins is an entomologist and evolutionary biologist based in Malindi, Kenya.  Other episodes you may enjoy: Tiny wasps emerge from a caterpillar, and reveal a hidden world Should We Conserve Parasites? Some Scientists Say Yes Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that's keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

In March, China became the first country to approve an invasive brain-computer interface beyond clinical trials. The implant, called NEO, is now available to some patients with limb paralysis due to a spinal cord injury. Ira talks with Wired staff writer Emily Mullin about the significance of this milestone. Plus, brain implants aren't the only development: China's entire biotech industry has skyrocketed in recent years. A decade ago, about 8% of new drug molecules were discovered in China. Now it's over 40%. And more clinical trials are now being conducted there than in the U.S. or Europe. Ira talks with health policy researcher So-Yeon Kang, who's been following the Chinese pharma industry's meteoric rise. Guests: Emily Mullin is a staff writer at Wired.  Dr. So-Yeon Kang is an Assistant Professor of Health Management and Policy at Georgetown University.  Other episodes you may enjoy: Advances In Brain-Computer Interfaces For People With Paralysis How China Is Driving Down Electricity Costs With Renewables Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that's keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

What happens when the skies are no longer dark at night? Writer Craig Childs biked from the brightest night sky, to the darkest, to find out what we lose when the lights don't go out. He joins Host Ira Flatow to talk about his book “The Wild Dark,” our SciFri Book Club pick for July and August. Plus, astronomer John Barentine fills us in on DarkSky International's latest report, “Artificial Light at Night: State of the Science 2026.” Read an excerpt from “The Wild Dark: Finding the Night Sky in the Age of Light.”  Guests: Craig Childs is the author of “The Wild Dark: Finding the Night Sky in the Age of Light.”  Dr. John Barentine is an astronomer and principal consultant at Dark Sky Consulting, LLC Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that's keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

The ongoing Ebola outbreak in the Democratic Republic of Congo and Uganda has become the third-largest on record. And while the regional response is more robust than it was during the largest outbreak, in 2014-2016, the U.S. has now largely divested from global health initiatives under President Trump. So it raises the question: What role should the U.S. play in global health? And how do we build systems that protect our collective health even as political winds change? Flora speaks with John Nkengasong, virologist and founder of the Africa CDC, about Ebola, what it took to curb HIV/AIDS, and how to make global health initiatives more resilient. Dr. Jessica Bartley is senior director of psychological services for the U.S. Olympic and Paralympic Committee. Guest:  Dr. John Nkengasong has led public health initiatives in the United States and across Africa for over 30 years. He is also the executive director for higher education, collaboratives, and special initiatives at the Mastercard Foundation. Other episodes you may enjoy: A virus hunter in Nigeria has thoughts on the Ebola outbreak Inside the Nebraska quarantine facility responding to hantavirus Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that's keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Gut feelings, trusting your gut, butterflies: We have lots of expressions about how our brains and our bowels are intertwined. But how well do we understand the science of this on the biomolecular level? And which of those organs is actually in the driver's seat?  Flora churned through the details with gastroneurologists Emeran Mayer and Trischa Pasricha on stage at the 2026 Aspen Ideas Festival in Colorado.  Guests: Dr. Emeran Mayer is distinguished research professor at the David Geffen School of Medicine at UCLA, and executive director of the G. Oppenheimer Center for Neurobiology of Stress and Resilience. Dr. Trisha Pasricha is a neurogastroenterologist and physician-scientist at Beth Israel Deaconess Medical Center as well as an assistant professor of medicine at Harvard Medical School. Other episodes you may enjoy: How to poop better, according to a gastroenterologist The Gurgling, Growling History Of The Gut A transcript for this episode is available at sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that's keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

The band Phish has toured for over 40 years. One of the draws of their legendary live shows—which can go on for 8 hours—is finding moments of “flow,” when the band members lock into an improvised jam, finding new musical ideas in real time. Phish fans live for these transcendent moments, but so do the musicians—to the point that Mike Gordon, the band's bass player, is funding scientific research to better understand flow state. In November 2025, Host Flora Lichtman sat down with Mike and his research collaborator, neuroscientist Greg Appelbaum, to unpack their research so far and how it's helping to inform other neuroscience. Guests: Mike Gordon is bassist and co-founder of the seminal improvisational rock band Phish.  Dr. Greg Appelbaum is a professor in the department of psychiatry at the University of California, San Diego.  A transcript for this episode is available at sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that's keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Americans pay roughly three times as much for prescription meds as people in other wealthy nations. But why? Tahir Amin argues it's largely to do with how our patent systems work. He's been on both sides of the issue: He spent a decade as an intellectual property lawyer, helping corporations use patents to protect their bottom lines. Then he moved to India and saw firsthand how the global patent system hampered access to HIV drugs. That led him to shift gears and create an advocacy organization aimed at changing the patent system to make access to medicines more equitable. He chats with Flora about how it all works, and his new book, “Pharma Monopoly.” Read an excerpt from “Pharma Monopoly: The Battle for the Future of Medicines.” Guest: Tahir Amin is a co-author of “Pharma Monopoly: The Battle for the Future of Medicines” and a founder and CEO of Initiatives for Medicine Access and Knowledge (I-MAK).  Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that's keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

If you hear “colonial America” and “science,” one name probably comes to mind: Benjamin Franklin. But he wasn't the only one thinking big thoughts and asking big questions. Many other natural philosophers were also looking at the world in new ways, and trying to make sense of how it worked.   In honor of the nation's 250th birthday, Host Ira Flatow traveled to Boston, the birthplace of the American Revolution, for a conversation with historian Robert Allison about scientific thought in early America. Guest: Dr. Robert Allison is a professor of history at Suffolk University, chair of Revolution 250, and president of the Colonial Society of Massachusetts.  Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that's keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Researchers have engineered an artificial cell out of chemicals and biomolecules that, at a basic level, can eat, grow, duplicate its own genetic code, and reproduce itself. The cell, dubbed SpudCell, is aimed at creating a chassis that can be adapted to create biological factories for the chemicals humans rely on for modern life, from fuels to pharmaceuticals. But it also raises the question of what it means for something to be “alive.”  Synthetic biologist Kate Adamala joins Host Ira Flatow to talk about the technological advance, the possibilities for the artificial cell, and a nonprofit organization she hopes will allow the SpudCell to spark an innovation in biotechnology. Guest: Dr. Kate Adamala is a synthetic biologist and an associate professor of  genetics, cell biology, and development at the University of Minnesota. Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that's keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Imagine this: You're an astronaut, you've landed on the moon, and as you're taking one small step for mankind, you kick up a bunch of lunar dirt. Now, tiny, jagged particles of dust are on your spacesuit, sticking to the spacecraft, getting in the machinery, and into your lungs. These are the kinds of problems planetary geologist Erica Jawin is trying to solve as NASA prepares for future moon bases. And what will you eat as an astronaut on the moon? Turns out that lunar dirt, or regolith, can be used to grow potatoes and other crops, just like Matt Damon did in “The Martian.” Flora talks to space biologist David Handy to learn more.  Guests: Dr. Erica Jawin is a planetary geologist at the National Air and Space Museum and a participating scientist on NASA's Artemis science team. Dr. David Handy is a space biologist studying how to grow potatoes in moon dirt at Oregon State University. Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that's keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Around 25 years ago, Ardem Patapoutian set out to investigate the fundamental biology behind our sense of touch. Through a long process of gene elimination, he identified a class of sensors in the cell membrane that turn physical pressure into an electrical signal. He changed the game in the field of sensation and perception, and in 2021 shared the Nobel Prize in Physiology or Medicine for his work.  He joined Host Flora Lichtman in November 2025 to talk about his research, the odd jobs he worked along the way, and how he found a sense of belonging in science. Guests: Dr. Ardem Patapoutian is a professor and the Presidential Endowed Chair in Neurobiology at the Scripps Research Institute in La Jolla, California. Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that's keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Hundreds of thousands of years ago, deep in the mountains of the Yukon, a ground squirrel pooped. That scat stayed frozen for millenia—until very recently, when researchers thawed it out and realized it was a literal data dump. They found traces of a surprising number of animals and plants, providing a detailed snapshot of life during the last ice age. Flora talks with biomolecular archaeologist Tyler Murchie about the gold mine that is ancient squirrel poop. And, if you liked our poop jokes, you'll want to hear how two different types of laughter are processed in the brain. Think big belly laughs versus polite chuckles in conversation. Ira chats with neuroscientist Sophie Scott about how these laughs originate and why we need them both. Guests: Dr. Tyler Murchie is a biomolecular archaeologist at the Hakai Institute in British Columbia and McMaster University in Ontario, Canada. Dr. Sophie Scott is a professor of cognitive neuroscience at University College London in England.  Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that's keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Pancreatic cancer is among the most deadly forms of cancer, and it can be difficult to catch early. But there's some good news: Clinical trials of a new drug called daraxonrasib found that it doubled the survival time of patients with advanced pancreatic cancer. And some oncologists are calling it a game changer—not just for pancreatic cancer, but potentially other forms of cancer too. Ira talks with oncologist Zev Wainberg, who led a clinical trial for the drug.  Plus, ALS is a degenerative disease that causes patients to lose their ability to walk, swallow and eventually to breathe. Now, there's a drug for a rare genetic form of ALS that can slow the progression or even reverse some of these symptoms. Ira talks with New York Times health and science reporter Pam Belluck about this new treatment. Guests: Dr. Zev Wainberg is a co-director of UCLA Health's GI Oncology Program. Pam Belluck is a health and science reporter for The New York Times. Other episodes you may enjoy: mRNA Vaccine For Pancreatic Cancer Continues To Show Promise How do clinical trials work, and who can participate? Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that's keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

On a hot summer day, there's nothing better than a dip in a cold pool. But you know who can ruin that for you? A scientist who studies pool chemistry. What chemical reactions are happening in that swimming pool when the water comes into contact with our bodily fluids and skin products? Environmental engineer Ernest Blatchley sits down with Flora Lichtman to discuss his findings after two decades of research, including how urine in a pool makes that chlorine smell, and his work to make the air of the Paris Olympics' indoor pools less toxic. Guest: Dr. Ernest Blatchley is a professor of environmental engineering at Purdue University, based in West Lafayette, Indiana. Other episodes you may enjoy: A ‘Dune'-Inspired Space Suit To Turn Astronaut Pee Into Water The Evolution Of An Enzyme Engineer Who Changed Chemistry Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that's keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.