Podcasts about Antimicrobial resistance

Sepsis and bloodstream infections (BSIs) are common and cause millions of deaths each year, with a disproportionate burden in low-income and middle-income countries. Tune in to learn from Jasmine R. Marcelin, MD, FACP, FIDSA, how inadequate antibiotic coverage can be linked to increased mortality and length of stay and how unnecessary broad-spectrum antibiotics can drive antimicrobial resistance. Topics covered include:The worldwide burden of sepsis and BSIsThe ongoing threat of antimicrobial resistanceUS and global health disparities in sepsis, BSI, and antimicrobial resistanceBarriers toward optimizing antibiotic use in BSIsPresenter:Jasmine R. Marcelin, MD, FACP, FIDSAAssociate Professor, Infectious DiseaseAssociate Medical Director, Antimicrobial Stewardship ProgramVice Chair for Belonging and Community Engagement, Department of Internal MedicineCo-Director, Digital Innovation & Social Media Strategy, Division of Infectious DiseasesUniversity of Nebraska Medical CenterOmaha, NebraskaLink to full program and downloadable slides:https://bit.ly/4inoXCxGet access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.  Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Unnecessary broad-spectrum antibiotics can drive antimicrobial resistance and cause adverse events, whereas inadequate antibiotic coverage is linked to increased mortality and length of stay for patients with bloodstream infections (BSIs). Listen now to learn from Jose Alexander, MD, D(ABMM), CIC, FCCM, SM/MB(ASCP), how to use rapid genotypic and phenotypic antimicrobial susceptibility testing results to inform antibiotic selection for patients with gram-negative BSIs. Topics covered include:Typical patterns of intrinsic antibiotic susceptibility and resistance in EnterobacteralesMechanisms of resistance in gram-negative bacteriaGenotypic rapid diagnostic tests for BSIsResistance markers for earlier targeted therapyRapid phenotypic antimicrobial susceptibility test platforms for blood culturesPresenter:Jose Alexander, MD, D(ABMM), CIC, FCCM, SM/MB(ASCP)Medical and Public Health MicrobiologistMedical and Technical Director of MicrobiologyAdventHealthOrlando, FloridaLink to full program and downloadable slides:https://bit.ly/4inoXCxGet access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Rapid phenotypic antimicrobial susceptibility testing (AST) significantly reduces time to actionable results and can improve antibiotic decision-making for patients with bloodstream infections. Listen in to learn from Michael P. Veve, PharmD, MPH, how to optimally integrate rapid phenotypic AST into clinical practice, including incorporation into your existing antimicrobial stewardship workflow. Topics covered include:Considerations for implementationDecision-making steps for implementationThe role of antimicrobial stewardship programs in AST workflowPresenter:Michael P. Veve, PharmD, MPHClinical Associate ProfessorDepartment of Pharmacy PracticeEugene Applebaum College of Pharmacy and Health SciencesWayne State UniversityClinical Pharmacy Specialist, Infectious DiseaseHenry Ford HospitalDetroit, MichiganLink to full program and downloadable slides:https://bit.ly/4inoXCxGet access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

It's World AMR Awareness Week (WAAW) and we have prepared a special episode in light of that. In this week's Communicable, Navaneeth Narayanan and Thomas Tängdén host Aula Abbara (London, UK), Guido Granata (Rome, Italy) and Tuomas Aro (Helsinki, Finland) to discuss the phenomenon of AMR in conflict and crisis zones. They elaborate on how difficult conditions and austere environments amplify the spread of AMR, drawing on findings from the ongoing conflicts in Ukraine, Gaza, Syria and other regions. Other topics covered include adapting antimicrobial stewardship and infection prevention and control (IPC) practices as well as the need for genuine political will and international collaboration to end conflicts and their exacerbation on AMR.This episode follows the webinar “Beyond the frontlines” organised by ESCMID's AMR Action Subcommittee for WAAW 2025, featuring the same guests, and is available on ESCMID Media. This Communicable episode was peer reviewed by Arjana Zerja of Mother Theresa University Hospital Centre, Tirana, Albania.  Related ESCMID and Communicable mediaESCMID Media, Part 1: Beyond the frontlines - tackling AMR in conflict and crisis zones, webinar Communicable episode 11: Nightmare series, part 2 – how to deal with carbapenemase producers Communicable episode 16: Climate change and infections – effects on clinical practice & sustainabilityResourcesTrainee Association of ESCIMD (TAE) Doctors without Borders (Médecins sans Frontières), Antibiogo, https://www.antibiogo.org/Doctors without Borders (Médecins sans Frontières), Mini-lab, https://fondation.msf.fr/en/projects/mini-lab Further ReadingAbbara A, et al. Unravelling the linkages between conflict and antimicrobial resistance. NPJ Antimicrob Resist. 2025. DOI: 10.1038/s44259-025-00099-yAbbara A, et al. A summary and appraisal of existing evidence of antimicrobial resistance in the Syrian conflict. Int J Infect Dis. 2018. DOI: 10.1016/j.ijid.2018.06.010Abu-Shomar R, et al. Multidrug-resistant Pseudomonas isolated from water at primary health care centers in Gaza, Palestine: a cross-sectional study. IJID Reg. 2025. DOI: 10.1016/j.ijregi.2025.100671Aldbis A, et al. The lived experience of patients with conflict associated injuries whose wounds are affected by antimicrobial resistant organisms: a qualitative study from northwest Syria. Confl Health. 2023. DOI: 10.1186/s13031-023-00501-4Aro T, et al. War on antimicrobial resistance: high carriage rates of multidrug-resistant bacteria among war-injured Ukrainian refugees. Clin Microbiol Infect. 2025. DOI: 10.1016/j.cmi.2025.07.010  Bazzi W, et al. Heavy Metal Toxicity in Armed Conflicts Potentiates AMR in A. baumannii by Selecting for Antibiotic and Heavy Metal Co-resistance Mechanisms. Front Microbiol. 2020. DOI: 10.3389/fmicb.2020.00068 Dewachi O. War Biology and Antimicrobial Resistance: The Case of Gaza, AMR Insights, 2024.Granata G, et al. The impact of armed conflict on the development and global spread of antibiotic resistance: a systematic review. Clin Microbiol Infect. 2024. DOI: 10.1016/j.cmi.2024.03.029 Huang XZ, et al. Molecular analysis of imipenem-resistant Acinetobacter baumannii isolated from US service members wounded in Iraq, 2003-2008. Epidemiol Infect. 2012. DOI: 10.1017/S0950268811002871Hujer KM, et al. Analysis of antibiotic resistance genes in multidrug-resistant Acinetobacter sp. isolates from military and civilian patients treated at the Walter Reed Army Medical Center. Antimicrob Agents Chemother. 2006. DOI: 10.1128/AAC.00778-06Karah N, et al. Teleclinical Microbiology: An Innovative Approach to Providing Web-Enabled Diagnostic Laboratory Services in Syria. Am J Clin Pathol. 2022. DOI: 10.1093/ajcp/aqab160Keen EF 3rd, et al. Evaluation of potential environmental contamination sources for the presence of multidrug-resistant bacteria linked to wound infections in combat casualties. Infect Control Hosp Epidemiol. 2012. DOI: 10.1086/667382Murray CK, et al. Recovery of multidrug-resistant bacteria from combat personnel evacuated from Iraq and Afghanistan at a single military treatment facility. Mil Med. 2009. DOI: 10.7205/milmed-d-03-8008Petersen K, et al. Diversity and clinical impact of Acinetobacter baumannii colonization and infection at a military medical center. J Clin Microbiol. 2011. DOI: 10.1128/JCM.00766-10Scott P, et al. An outbreak of multidrug-resistant Acinetobacter baumannii-calcoaceticus complex infection in the US military health care system associated with military operations in Iraq. Clin Infect Dis. 2007. DOI: 10.1086/518170Sensenig RA, et al. Longitudinal characterization of Acinetobacter baumannii-calcoaceticus complex, Klebsiella pneumoniae, and methicillin-resistant Staphylococcus aureus colonizing and infecting combat casualties. Am J Infect Control. 2012. DOI: 10.1016/j.ajic.2011.03.025World Health Organization. Fourth WHO Global Evidence Review on Health and Migration stresses that equitable access to and appropriate use of antibiotics for refugees and migrants is essential to tackling Antimicrobial Resistance, News, 2022.

In this episode, Jess and Sarah welcome Dr. Jomana Musmar to examine the critical and growing threat of antimicrobial resistance (AMR). The scientists explore alarming global statistics and the far-reaching implications of AMR for public health systems worldwide. Dr. Musmar emphasizes the urgent need for coordinated international responses, improved diagnostic capabilities, and enhanced patient advocacy in addressing this challenge. Throughout the conversation, the experts discuss the vital role healthcare professionals play in combating resistance while highlighting the importance of public awareness and proactive measures. The episode provides listeners with essential insights into one of the most pressing threats facing modern medicine and the collective action required to address it effectively. Video available on YouTube: https://youtu.be/_RQMTmmG-qU (00:00) Intro and Public Health Update (06:56) What Is A News Item That Caught Your Attention And Why? (12:03) Antimicrobial Resistance and Super Bugs (18:35) Responses Globally and In The U.S. (20:22) Is Hand Sanitizer Good or Bad?? (21:57) Overusing Antibiotics: Virus vs Bacteria (27:17) "Nightmare" Bacteria And A Shoutout To ER Physicians (33:46) What Is Giving Hope In Public Health And Science? https://strategiccoalitions.com/ www.linkedin.com/in/jomanamusmar www.advisorsofglobalhealth.com ----------------------------------------------------------------------------------------------------------------------- Interested in advertising with us? Please reach out to advertising@airwavemedia.com, with “Unbiased Science” in the subject line. PLEASE NOTE: The discussion and information provided in this podcast are for general educational, scientific, and informational purposes only and are not intended as, and should not be treated as, medical or other professional advice for any particular individual or individuals. Every person and medical issue is different, and diagnosis and treatment requires consideration of specific facts often unique to the individual. As such, the information contained in this podcast should not be used as a substitute for consultation with and/or treatment by a doctor or other medical professional. If you are experiencing any medical issue or have any medical concern, you should consult with a doctor or other medical professional. Further, due to the inherent limitations of a podcast such as this as well as ongoing scientific developments, we do not guarantee the completeness or accuracy of the information or analysis provided in this podcast, although, of course we always endeavor to provide comprehensive information and analysis. In no event may Unbiased Science or any of the participants in this podcast be held liable to the listener or anyone else for any decision allegedly made or action allegedly taken or not taken allegedly in reliance on the discussion or information in this podcast or for any damages allegedly resulting from such reliance. The information provided herein do not represent the views of our employers. Learn more about your ad choices. Visit megaphone.fm/adchoices

What if the answer to battling antibiotic-resistant infections isn't a new antibiotic, but harnessing viruses that have been quietly dominating bacterial populations?Bacteriophages, viruses that target and kill bacteria, have been saving lives for a century, but their true potential is only now being unlocked by modern machine learning. The race isn't just about discovering effective phages; it's about deploying the right therapy, personalized to the patient, before time runs out.On this episode, David Brühlmann welcomes José Luis Bila, Co-Founder and CEO of Precise Health. Driven by personal tragedy and an engineer's mindset, José is shaping a future where AI-powered phage therapy isn't a niche solution, but a scalable, accessible weapon against the superbugs that evade antibiotics. From building bioreactor capacity to navigating regulatory gray zones, José brings a rare blend of technical vision and practical urgency to a problem that affects families and health systems worldwide.Key topics discussed:The challenge of evolving bacteria and phages, and the question of whether it's possible to keep up with nature's pace through engineering new phages in silico (00:00)Overview of bacteriophage production: complexity, types of bioreactors used, and comparison with chemical synthesis (02:54)Bioproduction logistics: using CDMOs vs. in-house hospital production and the real-world timescales for manufacturing (02:32)Barriers for smaller or less funded hospitals, especially in low- and middle-income countries, with thoughts on hospital infrastructure differences worldwide (04:41)Creative solutions for cost-effective phage production in remote and underserved regions, such as the potential for single-use or mobile bioreactors (06:01)Why downstream processing and ensuring product purity is a bottleneck; the need for miniaturization and economic scalability (06:40)Parallels and differences in downstream processing between bacteriophages and viral vectors (09:15)The vital role of stability and shelf life for phage therapy logistics and economic viability (09:15)Regulatory pathways for phage therapy in Europe and beyond, including magistral preparations, ethical approvals, and adapting to digital tools for selection (12:39)The future vision: routine clinic entry through matching existing phage libraries, with longer-term goals of engineering bespoke phages via AI when necessary (15:52)José's perspective on building global infrastructure and making phage therapy cost-effective and universally accessible (18:08)José Bila's message: solutions to antimicrobial resistance are within reach. The biotech community must build accessible infrastructure, using AI and innovative systems to ensure phage therapy benefits reach every patient, everywhere.Connect with José Luis Bila:LinkedIn: www.linkedin.com/in/josé-luis-bila-phd-3b08a5a7Precise Health SA: www.precisehealth.ioInterested in how scientists are fighting superbugs? Learn how phage therapy and smart bioprocess design are helping outmaneuver drug-resistant pathogens. Check out this interview with one of our previous guests!Episodes 187-188: From Biology Is Messy to Designable: The Smart Bioprocessing Transformation with Carmen Jungo RhêmeNext step:Book a 20-minute call to help yo

Antibiotic resistance isn't just a looming problem. It's a global crisis. Every year, more than one million people die directly from resistant infections, and another 5 million die indirectly. Routine infections are becoming life-threatening, and healthcare systems worldwide are under pressure.Despite decades of warnings, pharmaceutical solutions are falling behind, while “superbugs” continue to outpace new drug development. If trends continue, by 2050, antibiotic resistance could claim 10 million lives annually and cost the world $1 trillion.Meet José Luis Bila, a chemist-turned-biotech-founder, who transformed personal tragedy into a mission to disrupt this deadly status quo. After losing both parents to antibiotic-resistant infections, José dedicated his career to the search for targeted, effective alternatives. Now, as Co-Founder and CEO of Precise Health SA, he's building AI-powered bacteriophage therapy platforms that promise to revolutionize personalized infection treatments and outmaneuver today's most stubborn bacteria.Why tune into this episode? Here are three standouts from José's story and his technical playbook:José's personal story: Losing both parents to antibiotic resistance and its impact on his career path. (00:00)Scope of the antibiotic resistance crisis: Global deaths, indirect impacts, and economic cost projections. (06:29)Why big pharma is pulling out of antibiotic development and why innovation may come from smaller startups. (07:29)Why antibiotic resistance persists: Static nature of antibiotics versus adaptable bacteria, and misuse of antibiotics. (09:45)Introduction to bacteriophage therapy and its specificity challenges. (11:46)The current slow, manual process for matching phages to infections and its limitations in urgent clinical settings. (13:08)How machine learning is being used at Precise Health to rapidly identify and source the right phages using genetic information. (16:58)The potential to reduce phage matching and delivery time from months to just days, and how smart batching and regional surveillance improve economics. (17:23)José Luis Bila's journey shows the power of science driven by purpose. Through persistence, he's pioneering AI-driven phage therapy - offering precision, hope, and a potential lifeline in the fight against antibiotic-resistant infections.Connect with José Luis Bila:LinkedIn: www.linkedin.com/in/josé-luis-bila-phd-3b08a5a7Precise Health SA: www.precisehealth.ioInterested in how scientists are fighting superbugs? Learn how phage therapy and smart bioprocess design are helping outmaneuver drug-resistant pathogens. Check out this interview with one of our previous guests!Episodes 187-188: From Biology Is Messy to Designable: The Smart Bioprocessing Transformation with Carmen Jungo RhêmeNext step:Book a 20-minute call to help you get started on any questions you may have about bioprocessing analytics: https://bruehlmann-consulting.com/call

Detectable HIV-1 RNA (viral load) can seem very worrisome for people living with HIV who are receiving antiretroviral therapy (ART) and for their healthcare professionals. Tune in to learn how Brian R. Wood, MD, differentiates HIV-1 RNA “blips” from persistent low-level viremia and from virologic failure, and how he handles each scenario.Presenter:Brian R. Wood, MDProfessor of MedicineDivision of Allergy and Infectious DiseasesUniversity of WashingtonSeattle, WashingtonLink to full program: https://bit.ly/4nS7rYEGet access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Episode Notes In this episode, DASON Clinical Pharmacist Liaison, Dr. April Dyer, talk to us about a publication in Health Affairs Scholar, entitled "Sustainable solutions to the continuous threat of antimicrobial resistance." The article can be viewed here: https://pubmed.ncbi.nlm.nih.gov/39916975/ For more information about DASON, please visit: https://dason.medicine.duke.edu/

This episode features Dr. Marjon de Vos PhD from the University of Groningen (the Netherlands) speaking about microbial ecology and evolution, and in particular how these affect antimicrobial resistance. She studies the urobiome as well as the factors that contribute to urinary tract infections and successful treatment of these infections with antibiotics. Her lab combines molecular biology techniques with phenotypic and growth measurements, as well as computational modeling. She has found evidence of microbial interactions mediating evolutionary potential of microorganisms – for example, in vitro experiments showed that in the presence of Enterococcus, E. coli speeds up its rate of developing antimicrobial resistance. Thus, interactions within the bacterial ecosystem may affect pathogens' sensitivity to antimicrobials. Prebiotics are a potential intervention: if bacteria that make a pathogen more susceptible to antimicrobials are already present in the urobiome, their numbers could be enhanced. Probiotics are another possibility. From a One Health perspective, such approaches are important to explore because they support antimicrobial stewardship and help maintain control of antimicrobials in the environment overall. Episode abbreviations and links: Preprint describing pathogens' differing rates and evolutionary trajectories towards antibiotic resistance based on other microbes present: Microbial interactions affect the tempo and mode of antibiotic resistance evolution Paper describing ecological interactions between different bacterial species in urinary tract infections: Interaction networks, ecological stability, and collective antibiotic tolerance in polymicrobial infections Research showing how 5 different bacteria affect the conjugation efficiency of E. coli: Community context influences the conjugation efficiency of Escherichia coli  About Dr. Marjon de Vos PhD: We investigate ecological and evolutionary processes in microbial communities, with a focus on infectious contexts. Our goal is to unravel the genotype–phenotype–fitness relationships within (evolving) communities and to identify the ecological factors that drive microbial evolution. To achieve this, we combine molecular biology techniques with phenotypic and growth measurements, as well as computational modeling. Our research places special emphasis on the urobiome and urinary tract infections in postmenopausal women, as well as on sepsis. By uncovering the fundamental ecological and evolutionary dynamics of microbial communities in infectious diseases, we aim to contribute to the development of strategies that alleviate infections and help curb the emergence and spread of antibiotic resistance.

In this episode, Dr. Brittany Rodriguez, Dr. Andrea Prinzi, and Dr. Denver Niles discuss their recent ASHE publication, “Uniting disciplines against antimicrobial resistance (AMR): highlights from a multidisciplinary inaugural AMR Summit.” They share key takeaways from the inaugural AMR Summit, held in November 2024, including rapid diagnostics, implementation science, next-generation sequencing, and strategies for engaging hospital leadership. The conversation closes with a call to action and priorities for advancing AMR efforts over the next two years.

What insights and lessons learned from the UN High Level Meeting on antimicrobial resistence last September can inform preparations for the upcoming UN High Level Meeting on non-communicable diseases? In this second episode of Intersections in Health, a podcast mini-series, we delve into #NCDs and #AMR common policy benefits and challenges with Professor Dame Sally Davies, UK Special Envoy on AMR, former Chief Medical Officer for England and former member of the WHO Executive Board 2014-2016, and Danilo Lo-Fo-Wong, WHO/Europe Regional Adviser and Programme Manager on the Control of Antimicrobial Resistance.We discuss the deathly threat of AMR for people with non-communicable diseases such as cancer, health diplomacy, the critical roles of civil society organisations in policy, health and the arts and the value of stepping outside our disciplinary bubbles.Tune in and share your feedback on the issues discussed. Please listen back to our previous episode exploring the intersections of NCDs and the triple planetary crisis and stay tuned for our final episode on NCDs and population ageing.This short series is part of WHO/Europe's count-down to the UN High Level Meeting on NCDs in September 2025. Hosted and produced by Maebh Ní Fhallúin Sound design and editing by David Barrett 

Gugs Mhlungu speaks to Prof. Vindana Chibabhai, Head of the Centre for Healthcare-Associated Infections, Antimicrobial Resistance and Mycoses, unpacking fungal diseases, from the everyday infections we think we know, to the more dangerous ones that often go misdiagnosed and the importance of their awareness. See omnystudio.com/listener for privacy information.

Send us a textDrug-resistant germs are hidden killers in more than one way. Not only are the microbes invisible to the human eye, in many places, they're invisible because people simply are not looking for them systematically.Doctors often do not know what infections their patients have and treat them based on best guesses, which allows for ineffective treatments and exacerbates drug resistance. Policymakers don't know which infections are most common among populations and cannot make informed decisions about needed treatments or vaccines.This is a major problem across Africa and a new report shows just how complex the problem is.The Mapping AMR and Antimicrobial use Partnership (MAAP), which included the One Health Trust as well as the African Society for Laboratory Medicine; Africa CDC; the East, Central, and Southern Africa Health Community; Innovative Support to Emergencies, Diseases, and Disasters, a nonprofit focused on technology and communication;  the clinical research group IQVIA; and the West African Health Organization, collected data from laboratories from 14 countries in Africa (Burkina Faso, Cameroon, Gabon, Ghana, Kenya, Eswatini, Malawi, Nigeria, Senegal, Sierra Leone, Tanzania, Uganda, Zambia, and Zimbabwe). “The study revealed significant gaps in bacteriology testing capacities,” the group, whose work was paid for by the UK government's Fleming Fund, wrote in PLoS Medicine.It's the biggest survey yet of testing for antimicrobial resistance – AMR or drug resistance – in Africa.Among the gaps: too little testing overall, a lack of laboratory capacities, and poor coordination and analysis of records. Many records were kept only on paper, which made them almost impossible to access.None of this surprises Dr. Sabiha Essack, South African Research Chair in Antibiotic Resistance and One Health and Professor in Pharmaceutical Sciences at the University of KwaZulu-Natal. In an ideal world, she says, a doctor, nurse or other professional should see a patient, test them to see what specific microbe is causing an infection, check to see which drugs will successfully fight that germ, and then treat the patient accordingly.Cheap point-of-care tests should be available everywhere and the results of those tests should be entered into systems that officials can use to make policy decisions, she says. Listen as she tells One World, One Health host Maggie Fox other ways to improve our knowledge about the drug-resistant infections that lurk out there. Want to know more? You can find One World, One Health episodes on drug-resistant infections in cancer patients; superbugs and microplastics; the personal toll of antibiotic resistance; one woman's antibiotic resistance nightmare; how to prevent drug resistance, and more.

In this episode Dominic Bowen and Dr. Ramanan Laxminarayan explore antimicrobial resistance (AMR) as a geopolitical flashpoint. Find out more about how drug resistance has already crossed the red line with untreatable infections, why AMR is not a future threat but a present crisis claiming 1.3 million lives annually, and how the erosion of antibiotic effectiveness undermines cancer care, surgery, and modern medicine. The conversation examines the political and economic reasons governments have been slow to act, the fragile economics of antibiotic development, and the risks of over-reliance on a handful of pharmaceutical firms. It also addresses the spread of multi-drug resistant infections in conflict zones such as Ukraine and Gaza, the importance of prevention through vaccines and sanitation, and the broader international risks as nationalism rises and global cooperation weakens.Dr. Ramanan Laxminarayan is the Founder and President of the One Health Trust and a Senior Research Scholar at Princeton University. He is also an Affiliate Professor at the University of Washington, a Visiting Professor at the University of Strathclyde, and a Senior Associate at the Johns Hopkins Bloomberg School of Public Health. Dr. Laxminarayan chairs the board of GARD-P, a global product development partnership created by the World Health Organization to develop and deliver new treatments for drug-resistant infections. He is also the founder and board chair of HealthCubed, which works to improve access to healthcare and diagnostics worldwide. Since 1995, he has been a leading global voice on antimicrobial resistance, bringing the issue to the United Nations General Assembly in 2016 and shaping health policy across Asia and Africa through the Global Antibiotic Resistance Partnership.The International Risk Podcast brings you conversations with global experts, frontline practitioners, and senior decision-makers who are shaping how we understand and respond to international risk. From geopolitical volatility and organised crime, to cybersecurity threats and hybrid warfare, each episode explores the forces transforming our world and what smart leaders must do to navigate them. Whether you're a board member, policymaker, or risk professional, The International Risk Podcast delivers actionable insights, sharp analysis, and real-world stories that matter. The International Risk Podcast – Reducing risk by increasing knowledge.Follow us on LinkedIn and Subscribe for all our updates!Tell us what you liked!

Listen in as Dr Trevor Van Schooneveld explores rapid syndromic testing for gastrointestinal and joint infections and discusses how to apply best practices for diagnostic and antimicrobial stewardship in syndromic testing. Topics covered include: Who should be tested for infectious diarrheaTypes of gastrointestinal syndromic panelsTypes of syndromic panels for joint infectionsReal-world applications for joint syndromic panelsPresenters: Trevor Van Schooneveld, MDProfessor, Division of Infectious DiseasesMedical Director, Antimicrobial Stewardship ProgramDepartment of Internal MedicineUniversity of Nebraska Medical CenterOmaha, NebraskaLink to full program: https://bit.ly/4mHOTtWGet access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify. 

In this edition of The Naked Scientists, why we need to pay closer attention to antimicrobial resistance in some of the world's poorest nations... Like this podcast? Please help us by supporting the Naked Scientists

Listen in as Michael Satlin, MD, MS, FIDSA,explores rapid syndromic testing for bloodstream infections and discusses how to apply best practices for diagnostic and antimicrobial stewardship in syndromic testing.Topics covered include:Types of upper and lower respiratory infection panelsConsiderations for when to use respiratory syndromic testingHow to use syndromic testing to guide both therapy escalation and de-escalationHow syndromic testing fits in with traditional testing methods, such as culture, antimicrobial susceptibility testing, Gram stain, and BAL cell count Presenter:Michael Satlin, MD, MS, FIDSAAssociate Professor of Medicine and Pathology and Laboratory MedicineWeill Cornell MedicineNew York, New YorkLink to full program: https://bit.ly/3UAB1oUGet access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.

Pour accéder à l'intégralité de ce podcast et écouter chaque semaine un nouvel épisode du Quart d'Heure Véto, c'est très simple, il vous suffit de vous abonner en cliquant sur ce lien : https://m.audiomeans.fr/s/S-yUNSBZSR Notes et référencesArticle : Kabir A, Lamichhane B, Habib T, Adams A, El-Sheikh Ali H, Slovis NM, Troedsson MHT, Helmy YA. Antimicrobial Resistance in Equines: A Growing Threat to Horse Health and Beyond-A Comprehensive Review. Antibiotics (Basel). 2024 Jul 29;13(8):713. doi: 10.3390/antibiotics13080713. PMID: 39200013; PMCID: PMC11350719. Retrouvez toute la synthèse sur la fiche podcast juste ici : https://audmns.com/DsOinpOPour nous suivre :1. Abonnez-vous à notre chaine pour profiter de l'intégralité des épisodes : Le Quart d'Heure Véto : décrypte et résume en moins de 15 min un article de biblio véto - Sur abonnement uniquementLe Véto du Mois : Partagez le temps d'une interview l'expérience de vétérinaires emblématiques de notre milieu, des rencontres conviviales, comme si nous étions dans votre salon au coin du feu. Podcasts bonus au fil des inspirations... 2. Le ScopeNous partageons avec vous nos dernières découvertes, inspirations, pistes de réflexion, nouveautés… À découvrir et utiliser dès maintenant, TOUT DE SUITE, dans votre quotidien de vétérinaire, de manager, de vie personnelle, de chef d'entreprise… Et tout cela en moins de 5 minutes top chrono un à 2 mardis par mois ! Je souhaite recevoir mon Scope : https://vetmasterclass.com/lescope/ 3. Contactez-nous, suivez-nous et donnez nous votre avis ! Des sujets que vous souhaiteriez approfondir, des références à partager, ou nous faire part de vos feed-backs :Abonnez-vous à notre chaine, donnez nous des étoiles, un commentaire et partagez autour de vous !Sur notre site : https://vetmasterclass.com/Sur Facebook : https://www.facebook.com/VmHorseSur Instagram : https://www.instagram.com/vetmasterclass/Sur YouTube : https://www.youtube.com/channel/UC18ovcWk9e-mFiTL34OQ03gSur Linkedin : https://www.linkedin.com/company/vetmasterclass-horse/about/Belle journée à tous, Et continuez à vivre votre métier avec Passion ! Hébergé par Audiomeans. Visitez audiomeans.fr/politique-de-confidentialite pour plus d'informations.

Listen in as Dr Emily Heil explores rapid syndromic testing for bloodstream infections and discusses how to apply best practices for diagnostic and antimicrobial stewardship in syndromic testing.Topics covered include:The importance of good blood culture practices and finding the balance between overuse and underuseBlood culture improvement programsThe utility of rapid diagnostic testsResistance markers for earlier targeted therapyPresenters:Emily Heil, PharmD, MS, BCIDP, AAHIVPProfessorDepartment of Practice, Sciences, and Health Outcomes ResearchUniversity of Maryland School of PharmacyBaltimore, MarylandLink to full program: https://bit.ly/45Ajz92Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.

pour accéder à l'intégralité de ce podcast et écouter chaque semaine un nouvel épisode du Quart d'Heure Véto, c'est très simple, il vous suffit de vous abonner en cliquant sur ce lien : https://m.audiomeans.fr/s/S-yUNSBZSR Notes et référencesArticle : Kabir A, Lamichhane B, Habib T, Adams A, El-Sheikh Ali H, Slovis NM, Troedsson MHT, Helmy YA. Antimicrobial Resistance in Equines: A Growing Threat to Horse Health and Beyond-A Comprehensive Review. Antibiotics (Basel). 2024 Jul 29;13(8):713. doi: 10.3390/antibiotics13080713. PMID: 39200013; PMCID: PMC11350719. Retrouvez toute la synthèse sur la fiche podcast juste ici : https://audmns.com/OWPecHEPour nous suivre :1. Abonnez-vous à notre chaine pour profiter de l'intégralité des épisodes : Le Quart d'Heure Véto : décrypte et résume en moins de 15 min un article de biblio véto - Sur abonnement uniquementLe Véto du Mois : Partagez le temps d'une interview l'expérience de vétérinaires emblématiques de notre milieu, des rencontres conviviales, comme si nous étions dans votre salon au coin du feu. Podcasts bonus au fil des inspirations... 2. Le ScopeNous partageons avec vous nos dernières découvertes, inspirations, pistes de réflexion, nouveautés… À découvrir et utiliser dès maintenant, TOUT DE SUITE, dans votre quotidien de vétérinaire, de manager, de vie personnelle, de chef d'entreprise… Et tout cela en moins de 5 minutes top chrono un à 2 mardis par mois ! Je souhaite recevoir mon Scope : https://vetmasterclass.com/lescope/ 3. Contactez-nous, suivez-nous et donnez nous votre avis ! Des sujets que vous souhaiteriez approfondir, des références à partager, ou nous faire part de vos feed-backs :Abonnez-vous à notre chaine, donnez nous des étoiles, un commentaire et partagez autour de vous !Sur notre site : https://vetmasterclass.com/Sur Facebook : https://www.facebook.com/VmHorseSur Instagram : https://www.instagram.com/vetmasterclass/Sur YouTube : https://www.youtube.com/channel/UC18ovcWk9e-mFiTL34OQ03gSur Linkedin : https://www.linkedin.com/company/vetmasterclass-horse/about/Belle journée à tous, Et continuez à vivre votre métier avec Passion ! Hébergé par Audiomeans. Visitez audiomeans.fr/politique-de-confidentialite pour plus d'informations.

Let's say you were asked to name the greatest health risks facing the planet. Priceton University economist Ramanan Laxminarayan, founder and director of the One Health Trust, would urgently suggest you include anti-microbial resistance near the top of that list. “We're really in the middle of a crisis right now,” he tells interview David Edmonds in this Social Science Bites podcast. “Every year, about 5 million people die of infections that are associated with antibiotic resistance -- 5 million. That's nearly twice the number of people who die of HIV, TB and malaria, put together -- put together. Antibiotic resistance and associated deaths are the third leading cause of death in the world, after heart disease and stroke. So you're talking about something that's really, really big, and this is not in the future. It is right now.” The underlying problem, simply put, is that humans are squandering perhaps the greatest health innovations in the last century by using antibiotics stupidly, allowing pathogens to develop resistance and thus rendering existing antibiotics worthless. For the last 30 years and in particular through One Health Trust and as director of the World Health Organization Collaborating Center for Antimicrobial Resistance, Laxminarayan has labored to make both shine a light on anti-microbial resistance and push for policies to address it. This, he tells Edmonds, is a social science problem even more so than a medical science problem – but not the exclusive province of either. “I think one of the failures of economics,” he says, “in some ways, is that we don't take the trouble to understand the nitty gritty of the actual other field, especially when it deals with health economics or environmental economics.” In addition to his role as a senior research scholar at Princeton, Laxminarayan is an affiliate professor at the University of Washington, a senior associate at the Johns Hopkins Bloomberg School of Public Health, and a visiting professor at the University of Strathclyde.

Microbiologist and Associate Professor at the University of Washington Dr. Olusegun Soge reviews four U.S. based surveillance programs: GISP, eGISP, SURGG, and CARGOS – the umbrella program rolled out in August 2024. Dr. Soge and National STD Curriculum Podcast Host Dr. Meena Ramchandani also discuss a vaccine and another STI pathogen developing resistance. View episode transcript and references at www.std.uw.edu.This podcast is dedicated to an STD [sexually transmitted disease] review for health care professionals who are interested in remaining up-to-date on the diagnosis, management, and prevention of STDs. Editor and host Dr. Meena Ramchandani is an Assistant Professor of Medicine at the University of Washington (UW), Program Director of the UW Infectious Diseases Fellowship Program, and Associate Editor of the National STD Curriculum.   

On University at Albany Week: Understanding what drives antimicrobial resistance is crucial. Cheryl Andam, associate professor in the department of biological sciences at the RNA Institute, identifies a new mechanism. Cheryl Andam is an associate professor in UAlbany's Department of Biological Sciences. She works on the genome evolution of bacterial pathogens, with a focus on antimicrobial […]

A common description of antibiotic action aims to classify them between “bactericidal” or “bacteriostatic”. Although these phenomena have robust in vitro foundations, the clinical translation of these concepts is sometimes difficult to ascertain. This controversial topic has important conceptual ramifications to treat severe infections. Today, we will discuss this topic with an expert in field.  Watch the video version here: https://youtu.be/3z4BItBrzbk Topics discussed: The definitions of “cidal” vs “static” antibiotics The clinical applicability of the above terms in terms of antibiotic choice and syndromatic approaches antibiotic choices and the controversy between bactericidal and bacteriostatic antibiotics.  Guest: Brad Spellberg, MD.  Chief Medical Officer at the Los Angeles General Medical Center  Links: ASM and IDSA launch the Interdisciplinary Meeting on Antimicrobial Resistance and Innovation (IMARI) in 2026 Watch this session on YouTube This episode is brought to you by the Antimicrobial Agents and Chemotherapy Journal.  Visit asm.org/aac to browse issues and/or submit a manuscript. If you plan to publish in AAC, ASM Members get up to 50% off publishing fees. Visit asm.org/joinasm to sign up.

Send us a textIt's a common scenario for a cancer patient. They're undergoing treatment and get what's known as a peripherally inserted central catheter or PICC (pronounced “pick”) line to make it more convenient to administer drugs. They are in and out of the hospital or just the clinic frequently to see various providers. The treatment they receive may run down their immune system a little bit. Just having cancer may have damaged their immune system.So then they get an infection.Perhaps it's no big deal. A round of antibiotics may take care of it. However, increasingly, these infections are resistant to antibiotics – something known as antimicrobial resistance or AMR.Then, the patient must wait weeks or even months to resume cancer treatment while the infection is treated. And, all too often, the infection itself may kill the patient. In fact, infections are the second-leading cause of death for cancer patients.Dr. Yehoda M. Martei, Assistant Professor of Medicine (Hematology-Oncology) at the Hospital of the University of Pennsylvania, and colleagues have been working to find out just how common these infections are. Among patients hospitalized for treatment, cancer patients were up to twice as likely to get a drug-resistant infection, she and colleagues found. Among outpatients – people getting treatment at clinics or offices but not staying in the hospital – cancer patients had three times the risk of drug-resistant infections.Listen as Dr. Martei tells One World, One Health host Maggie Fox about her findings, what they mean, and what must be done to protect cancer patients and ensure infections don't stop them from getting the treatment they need.

Microbiologist and Associate Professor at the University of Washington Dr. Olusegun Soge reviews six different ways that the microbiology of Neisseria gonorrhoeae contributes to its antimicrobrial resistance. Dr. Soge and National STD Curriculum Podcast Host Dr. Meena Ramchandani then explore how current overuse and misuse of antibiotics in the STI field might be part of the problem. View episode transcript at www.std.uw.edu.This podcast is dedicated to an STD [sexually transmitted disease] review for health care professionals who are interested in remaining up-to-date on the diagnosis, management, and prevention of STDs. Editor and host Dr. Meena Ramchandani is an Assistant Professor of Medicine at the University of Washington (UW), Program Director of the UW Infectious Diseases Fellowship Program, and Associate Editor of the National STD Curriculum.  

Measles cases in North America have exceeded 3,200, mainly due to low vaccination rates, with children most affected. Clinicians are urged to verify immunization status and close gaps. The EU is restricting azithromycin use amid rising antimicrobial resistance, dropping certain indications and adding new warnings. A trial shows methotrexate is a viable first-line alternative to prednisone for pulmonary sarcoidosis with differing side effects.

In the third and final episode of our miniseries on infectious disease diagnostics, Jonathan sits down with global diagnostics leader Rosanna Peeling, Professor and Chair of Diagnostics Research at the London School of Hygiene and Tropical Medicine. Together, they explore the life-saving role of diagnostics in global health, from battling STDs to confronting COVID-19, and examine how equitable access, social innovation, and regulatory reform can transform disease control and pandemic preparedness.   Timestamps: 00:00 – Introduction 06:09 – Rosanna's interest in microbiology 08:12 – The IDC's work 10:52 – Funding for diagnostics 13:30 – Diagnostic testing in low-resource settings 18:21 – Chlamydia research 24:19 – Regulatory approval challenges 29:35 – Social innovation 34:08 – Clinician adaptation 37:10 – Current diagnostic innovations 40:30 – Rosana's three wishes for healthcare

CDC and the World Health Organization consider Neisseria gonorrhoeae an urgent antibiotic-resistant threat because it continuously develops resistance. Microbiologist and Associate Professor at the University of Washington Dr. Olusegun Soge provides a historical overview of past efforts, an update on the current situation, why global surveillance is so important, and a potential new treatment for uncomplicated gonorrhea. View episode transcript at www.std.uw.edu.This podcast is dedicated to an STD [sexually transmitted disease] review for health care professionals who are interested in remaining up-to-date on the diagnosis, management, and prevention of STDs. Editor and host Dr. Meena Ramchandani is an Assistant Professor of Medicine at the University of Washington (UW), Program Director of the UW Infectious Diseases Fellowship Program, and Associate Editor of the National STD Curriculum.  

Getting to Know OH: The podcast series where public health's questions meet One Health answers for the fight against AMR.   Dr. Jan Sargeant helps build our One Health understanding of AMR in this episode focused on antimicrobial resistance and antimicrobial use in Canadian food-producing animals. The episode highlights how veterinarians and producers are working to use antibiotics responsibly, gains made, challenges that remain, and key interventions that could do more to preserve the effectiveness of antimicrobials for people and animals alike.

Health care public relations leader Melanie Doupé Gaiser discusses her article, "Antimicrobial resistance needs a publicist." She highlights antimicrobial resistance (AMR) as an urgent and deadly public health crisis that is not receiving the attention it warrants, particularly in the U.S. Melanie shares her personal stake in the issue, living with a critical antibiotic allergy, and underscores the looming threat of a post-antibiotic era where common infections could become fatal. The conversation covers the staggering potential human and economic costs of AMR, the reasons behind its low public profile despite these risks, and legislative efforts. Melanie issues a compelling call to action for everyone—researchers, health care professionals, patients, and the general public—to become "AMR publicists" by sharing stories, engaging with media, and advocating for policy changes. The key takeaway is: Collective public and professional advocacy is crucial to elevate AMR on the national agenda, drive innovation in antibiotic development, and implement policies to combat this growing global threat. Our presenting sponsor is Microsoft Dragon Copilot. Microsoft Dragon Copilot, your AI assistant for clinical workflow, is transforming how clinicians work. Now you can streamline and customize documentation, surface information right at the point of care, and automate tasks with just a click. Part of Microsoft Cloud for Healthcare, Dragon Copilot offers an extensible AI workspace and a single, integrated platform to help unlock new levels of efficiency. Plus, it's backed by a proven track record and decades of clinical expertise—and it's built on a foundation of trust. It's time to ease your administrative burdens and stay focused on what matters most with Dragon Copilot, your AI assistant for clinical workflow. VISIT SPONSOR → https://aka.ms/kevinmd SUBSCRIBE TO THE PODCAST → https://www.kevinmd.com/podcast RECOMMENDED BY KEVINMD → https://www.kevinmd.com/recommended

In the last decade, there have been major changes in the approach of the treatment of pneumonia, in particular, with the availability of new diagnostic tools. Additionally, new drugs have been approved for the treatment of pneumonia. We discuss the approach to the management of pneumonia with a person who has spent most of his professional career working on this topic. Topics discussed: Definitions and nomenclature of pneumonia and evolution of these terms Changes in the diagnosis of pneumonia Ttherapeutic changes and future approaches for the treatment of pneumonia. Guest: Daniel M Musher, M.D. Links: ASM and IDSA launch the Interdisciplinary Meeting on Antimicrobial Resistance and Innovation (IMARI) in 2026 This episode is brought to you by the Antimicrobial Agents and Chemotherapy Journal.  Visit asm.org/aac to browse issues and/or submit a manuscript. If you plan to publish in AAC, ASM Members get up to 50% off publishing fees. Visit asm.org/joinasm to sign up.

Send us a textPlastic is everywhere. So are drug-resistant microbes.What happens when the two team up?A raft of new studies show that bacteria can grow well on plastics, especially on microplastics. Other studies show just how widespread microplastics are – they are found in every ocean and sea tested so far. The most startling studies show these tiny bits of plastics can also build up in the human body, including in the liver and brain.Science is done piece by piece, study by study, with no single study painting the whole picture. Now a team at Boston University has added one piece to the puzzle, with a study demonstrating that drug-resistant bacteria grow well on microplastics.Neila Gross, a PhD candidate at BU, helped lead the research. Her team confirmed that E. coli bacteria form mats known as biofilms especially well on microplastics. The team found that antibiotic-resistant bacteria grew better when they were grown on microplastics.This raises a specter of billions of tiny pieces of plastic spreading drug-resistant bacteria around the world and being ingested and breathed in by animals from shellfish to marine mammals and, likely, people.Listen as Neila chats with One World, One Health host Maggie Fox about how this happens and what it might mean for the spread of antimicrobial resistance.

In the second episode of our miniseries on infectious disease diagnostics, Jonathan is joined by molecular epidemiologist Rodney Rohde, Regents' Professor at Texas State University, USA. Together, they explore diagnostic innovations in the fight against antimicrobial resistance, gaps in zoonotic disease detection, and the persistent challenge of vaccine hesitancy. Timestamps: 00:00 – Introduction 01:45 – Breakthroughs in molecular diagnostics 08:30 – Diagnostic tools to combat superbugs 14:18 – Can bacteriophages replace antibiotics? 19:04 – Controlling rabies and hantavirus 28:33 – Diagnostic successes and failures from COVID-19 35:22 – How do we address vaccine hesitancy? 44:10 – Preparing for the next pandemic 47:03 – Rohde's three wishes for healthcare

Send us an inquiry through a text message here!Welcome to another episode of The Veterinary Roundtable! In this episode, the ladies discuss the challenges of treating patients at a higher elevation, a handful of My Pets Wellness clinics closing overnight, keeping antimicrobial resistance in mind when treating patients, and more!Do you have a question, story, or inquiry for The Veterinary Roundtable? Send us a text from the link above, ask us on any social media platform, or email theveterinaryroundtable@gmail.com!Episodes of The Veterinary Roundtable are on all podcast services along with video form on YouTube!Instagram: https://tinyurl.com/2h27xnfuTikTok: https://tinyurl.com/m8f62ameYouTube: https://tinyurl.com/48njfywdTIMESTAMPSIntro 00:00Pits And Peaks 04:34Tails From The Trenches 11:32My Pets Wellness Closes All Vet Clinics Overnight 16:50New Immunotherapy Treatment May Delay Metastasis In Dogs With Osteosarcoma 21:18Case Collections 23:36Listener Loves Intranasal Bordetella 31:10Treating Patients At A Higher Elevation 34:00Keep Antimicrobial Resistance In Mind When Treating Patients 37:44Outro 44:28

Friday, April 4th, 2025Today, the acting Inspector General for the Department of Defense has launched an investigation into Pete Hegseth's Signal chat messages; the Senate has voted to rescind some of Trump's tariffs which caused the third biggest stock market crash in modern history; federal prosecutors have dropped the charges against the guy Nancy Mace says assaulted her; massive layoffs at the FDA include scientists working on bird flu and pet food safety; Judge Boasberg held a hearing in the contempt proceedings in the Alien Enemies Act case; and Allison delivers your Good News.Guest: Mayor Karen BassMayor Bass Applauds FEMA's Extension of Deadline for No-Cost Debris Removal ProgramWildfire Recovery Resources - LA CityResources Centers Available For Those Impacted by L.A. WildfiresEARTH DAY LA - April 25Mayor Karen BassMayor Karen Bass (@mayor.lacity.gov) — BlueskyGuest: John FugelsangTell Me Everything — John FugelsangThe John Fugelsang PodcastSiriusXM ProgressThank You, Pique LifeGet 20% off on the Radiant Skin Duo, plus a FREE starter kit at Piquelife.com/dailybeans.Stories:Pentagon watchdog launches probe of Hegseth Signal messages | CNN PoliticsSenate Votes to Rescind Some Trump Tariffs, With G.O.P. Support | The New York TimesTrump contradicts aides, talking points on purpose of global tariffs | The Washington PostVeterinarians working on bird flu, pet food safety are fired in HHS purge | The Washington PostCharge dropped against foster advocate accused of assaulting Rep. Nancy Mace | The Washington PostGood Trouble:Hands off 2025 is tomorrow! Go to HandsOff2025.com to find the rally nearest you, put on your comfy shoes, stay hydrated and KNOW YOUR RIGHTS. Know Your Rights | Protesters' Rights | ACLU From The Good NewsShit Show (Instrumental) | YouTubeItalian Government -Citizenship by descent (iure sanguinis)Public Service Loan Forgiveness (PSLF) Federal workers - feel free to email me at fedoath@pm.me and let me know what you're going to do, or just vent. I'm always here to listen.Share your Good News or Good Trouble:https://www.dailybeanspod.com/good/ Check out other MSW Media podcastshttps://mswmedia.com/shows/Subscribe for free to MuellerSheWrote on Substackhttps://muellershewrote.substack.comFollow AG and Dana on Social MediaDr. Allison Gill Substack|Muellershewrote, Twitter|@MuellerSheWrote, Threads|@muellershewrote, TikTok|@muellershewrote, IG|muellershewrote, BlueSky|@muellershewroteDana GoldbergTwitter|@DGComedy, IG|dgcomedy, facebook|dgcomedy, IG|dgcomedy, danagoldberg.com, BlueSky|@dgcomedyHave some good news; a confession; or a correction to share?Good News & Confessions - The Daily Beanshttps://www.dailybeanspod.com/confessional/ Listener Survey:http://survey.podtrac.com/start-survey.aspx?pubid=BffJOlI7qQcF&ver=shortFollow the Podcast on Apple:The Daily Beans on Apple PodcastsWant to support the show and get it ad-free and early?Supercasthttps://dailybeans.supercast.com/Patreon https://patreon.com/thedailybeansOr subscribe on Apple Podcasts with our affiliate linkThe Daily Beans on Apple Podcasts

In this episode of the EMJ Podcast, Jonathan Sackier sits down with Jose Alexander, Clinical Microbiologist and Director of Microbiology at AdventHealth Orlando, to explore the cutting edge of infectious disease diagnostics. From next-generation sequencing to rapid tests for brain-eating amoeba, Alexander shares insights into the latest innovations shaping the field, the fight against antimicrobial resistance, and the future of microbiology diagnostics. Timestamps: 00:00 – Introduction 03:55 – Alexander's introduction to microbiology 05:42 – Developing a rapid test for a brain-eating amoeba 09:40 – Where is this amoeba found? 12:13 – Next-generation sequencing in infectious disease 14:36 – Streptococcus pneumoniae serotype/genotype service 17:06 – Vaccine hesitancy 19:03 – Antimicrobial resistance 22:02 – The discovery of a novel variant of Klebsiella pneumoniae 24:32 – The clinical use of bacteriophages 27:01 – The future of the field 28:41 – Alexander's three wishes for healthcare

Matters Microbial #84: Detecting Pathogens — and Worse — in Wastewater March 27, 2025 Today, Dr. Rachel Poretsky, Associate Professor of Biological Sciences at the University of Illinois Chicago joins the #QualityQuorum to discuss how examining wastewater (and related water) can give insights into the presence of pathogen antimicrobial resistance genes and even microbial ecology. Host: Mark O. Martin Guest: Rachel Poretsky Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode A link to demonstrate the wonders of the Marine Biological Laboratories' Microbial Diversity course, which I know for a fact is life changing. Recommended by David Ranada, an article about water bottles and microbes.   An essay about the Chicago River and cholera, which led to the necessity of effective waste water treatment. An overview of the complexities of waste water treatment.  Here is a video on that topic.   An essay by Carl Zimmer about the microbial ecology of lakes…and human beings. How “recreational water quality” is determined. An article describing the microbiota associated with human biological waste with an amusing name (scroll down). How qPCR can be used to determine the prevalence of specific microbes. A recent article from Dr. Poretsky's research group, investigating how antimicrobial resistance genes can move through a hospital waste water system. A link to the Bacterial-Viral Bioinformatics Resource Center, for which Dr. Poretsky is a Principle Investigator. The Illinois state wastewater surveillance dashboard.  Fascinating! A Discovery Channel documentary on virus hunting and surveillance that includes Dr. Poretsky. Dr. Poretsky's faculty webpage. Dr. Poretsky's webpage for her research group. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com

In this edition of The Naked Scientists, Antimicrobial Resistance, or AMR, is going under our microscope. What is it, how does it happen, what's the scale of the threat, and how can we fight back? Like this podcast? Please help us by supporting the Naked Scientists

"I have wondered if heart attacks could be an issue because it is a shock to the body when you walk into a cold shower. I don't know. When you did those plunges, did you sort of slowly go in, or did you go in all at once because it's easier that way?" -Alexandra Paul "No. I go all in, all at once. For me, if I do the gradual process—where I'm just dipping a toe in, literally just dipping a toe in—the feedback that my mind will give me is: ‘Danger, danger, danger. Do not do this.' So I do it because I want to override that fear response and the danger signals that my brain is telling me. And I'm grateful. I'm like, ‘Thank you so much for those signals. You're working. Excellent. And we're going to go and do this.' So I will literally just go right in…" -Jason Wrobel In this episode, Alexandra and Jason dive into the hot and cold of wellness—literally, exploring the pros and cons of cold plunging, from its potential benefits for mental health, inflammation, and immunity to the risks you should know before taking the plunge. They also tackle the rise of superbugs, antibiotic resistance, what's causing it, how it can impact you, and how you can protect yourself. Plus, Alexandra shares her personal experiences with antibiotics, her best advice for restoring gut health, and her go-to tips for staying healthy and happy! Podcast sponsor: Vedge Vegan Collagen: vedgenutrition.com – use code S4G for 30% off your order. - https://www.vedgenutrition.com/ What we discuss in this episode: The history and evolution of antibiotic use. How to protect yourself in hospital settings. The link between animal protein consumption and antibiotic resistance. What cold plunging involves and how it works. The power of setting boundaries.  The importance of staying present and grounded. How volunteering can enrich your life. Resources: Health effects of voluntary exposure to cold water – a continuing subject of debate - PMC Association of Diet and Antimicrobial Resistance in Healthy U.S. Adults - PubMed   Click the link below to support the FISCAL Act https://switch4good.org/fiscal-act/ Share the website and get your resources here https://kidsandmilk.org/ Send us a voice message and ask a question. We want to hear from you! Switch4Good.org/podcast Dairy-Free Swaps Guide: Easy Anti-Inflammatory Meals, Recipes, and Tips https://switch4good.org/dairy-free-swaps-guide SUPPORT SWITCH4GOOD https://switch4good.org/support-us/ ★☆★ JOIN OUR PRIVATE FACEBOOK GROUP ★☆★  https://www.facebook.com/groups/podcastchat ★☆★ SWITCH4GOOD WEBSITE ★☆★ https://switch4good.org/ ★☆★ ONLINE STORE ★☆★ https://shop.switch4good.org/shop/ ★☆★ FOLLOW US ON INSTAGRAM ★☆★ https://www.instagram.com/Switch4Good/ ★☆★ LIKE US ON FACEBOOK ★☆★ https://www.facebook.com/Switch4Good/ ★☆★ FOLLOW US ON TWITTER ★☆★ https://twitter.com/Switch4GoodOrg ★☆★ AMAZON STORE ★☆★ https://www.amazon.com/shop/switch4good ★☆★ DOWNLOAD THE ABILLION APP ★☆★ https://app.abillion.com/users/switch4good

States rush to ban food dyes ahead of federal action; NIH cuts funds for studies of vaccine hesitancy; RFK Jr. ridiculed for urging vitamin A for measles; Brain tumors in firefighters show signature of chemical exposure; Unpacking the causes of numbness, tingling and pain in lower extremities; Class-action lawsuit targets Depo-Provera as contributor to meningioma brain tumors; Uncovering the mystery of Trump's 20+ pound weight loss; Microplastics implicated in spiraling antibiotic resistance.

John Maytham speaks with Nazir Ismail, Head of Clinical Microbiology and Infectious Diseases at Wits University, about an extraordinary new discovery in the immune system that could revolutionize the fight against antibiotic-resistant infections. Scientists have found that the proteasome, previously known for recycling proteins, has an unexpected ability to produce bacteria-killing chemicals.See omnystudio.com/listener for privacy information.

Dr. Don and Professor Ben talk about the risks of letting a parrot stir you coffee with a spoon every day. Dr. Don - risky ☣️ Professor Ben - not risky

A recent report from the Engineering Research Visioning Alliance emphasizes the urgent need for engineering-directed research to mitigate the growing threat of antimicrobial resistance. Anita Shukla, PhD, a professor of engineering at Brown University, discusses its findings with JAMA Medical News Associate Managing Editor Kate Schweitzer and presents several key opportunities. Related Content: Five Engineering Advancements That May Help Solve the Growing Threat of Antimicrobial Resistance

  What if the lessons learned from a conflict zone could transform military medicine worldwide? Join us as we promise to reveal groundbreaking insights into combat casualty care with John Quinn, MD, MPH, PhD, EMT-P, a leading voice in Emergency Medicine and Combat Casualty Care. Dr. Quinn shares his experiences and pivotal lessons from the war in Ukraine, providing an in-depth look at how military medical operations have evolved in response to the challenges faced in high-stakes environments. Gain valuable knowledge on damage control, resuscitation, and the strategic decisions made from the point of injury to more advanced medical roles.    The complexities of combat medicine are not for the faint-hearted. In this compelling episode, we confront the realities of triage and care under fire, with medical personnel often working without senior guidance amidst the chaos of large-scale combat. Our discussion sheds light on the critical importance of Tactical Combat Casualty Care and the intricate decisions around tourniquet use when resources are stretched thin. Dr. Quinn emphasizes the skills required to manage such intense scenarios, ensuring listeners understand the vital balance between operational readiness and effective medical intervention.     Handling pain management and blood supply logistics in conflict zones is no small feat. We explore the intricate challenges of ensuring adequate supplies and effective pain medication, particularly in the context of Ukraine's ongoing conflict. Dr. Quinn delves into the necessity of a robust supply of universal donor blood and the pressing need for improved clinical governance to support pre-hospital blood transfusion capabilities. The episode addresses the pressing issue of antimicrobial resistance and antibiotics' critical role in these settings, highlighting the need for structured guidance and oversight to navigate the complexities of treating diverse patient populations. Chapter Timestamps 00:02 Military Medicine and Operational Readiness 09:30 Combat Medicine and Triage Challenges 14:08 Challenges in Pre-Hospital Pain Management 17:43 Combat Medic Challenges and Solutions   Chapters with Summaries (00:02) Military Medicine and Operational Readiness This chapter explores the insights and experiences shared by Dr. John Quinn, the lead author of a pivotal article on pre-hospital lessons from the war in Ukraine, focusing on damage control, resuscitation, and surgery from point of injury to role two. Dr. Quinn, with a background as a paramedic and emergency medicine physician, recounts his involvement in Ukraine since 2014, highlighting the evolution of military medical operations up to the large-scale invasion by Russia. We discuss the collaborative effort behind the article, featuring a diverse team of experts, including traumatology surgeons, paramedics, and academic figures, all working to enhance combat casualty care. Dr. Quinn emphasizes the importance of incorporating Ukrainian academics' insights and using NATO's terminology for lessons learned, providing a comprehensive look at the on-the-ground experiences and challenges faced in providing timely and effective medical care in conflict zones.   (09:30) Combat Medicine and Triage Challenges This chapter addresses the complex challenges faced by medical personnel in large-scale combat operations, particularly in the context of the ongoing conflict involving Russian forces. We explore how medical workers, including international volunteers, are specifically targeted, necessitating unique approaches to operational security, communication, and personal protective equipment. The discussion emphasizes the importance of tactical combat casualty care, especially in making critical triage decisions without the guidance of senior clinical decision-makers. With an overwhelming number of patients and limited evacuation capabilities, medical personnel must navigate the intricacies of tourniquet use, balancing between preventative application and conversion to pressure dressings as per TCCC protocols. The chapter highlights the essential skills required to manage care under fire and the need for timely assessment by qualified providers to reduce morbidity and enhance force effectiveness in the battlefield.   (14:08) Challenges in Pre-Hospital Pain Management This chapter addresses the challenges and intricacies of pain management and blood supply logistics in conflict zones, particularly focusing on the context of Ukraine. We explore the inadequacies of certain medications like Nalbuphine, which can complicate effective pain management when transitioning patients to higher levels of care. The importance of having access to more effective drugs such as ketamine and fentanyl is emphasized, although logistical challenges in their distribution are acknowledged. Additionally, we highlight the critical need for an ample supply of universal donor blood and low-titer O blood products during large-scale combat operations. The chapter underscores the logistical hurdles in ensuring these supplies are available before they spoil and discusses the inadequacy of traditional walking blood banks in high-casualty scenarios, advocating for improved clinical governance to enable broader pre-hospital blood transfusion capabilities.   (17:43) Combat Medic Challenges and Solutions This chapter highlights the critical importance of antibiotics in deployed medical settings, emphasizing the challenges of antimicrobial resistance, particularly in Ukraine. We explore the need for a structured antimicrobial guidance system, informed by biogram data, to prevent inappropriate dosing and resistance. The discussion extends to the complexities of treating diverse age groups, including elderly and pediatric patients, who may have additional medical conditions or require specialized care. Additionally, we stress the significance of clinical governance in ensuring that medical personnel, whether affiliated with NGOs or the military, operate under proper oversight and standards. Finally, we identify the top three priorities for improvement: ensuring an unlimited supply of low-titer universal donor blood, enhancing training and clinical decision-making, and leveraging data for effective medical logistics and planning.   Take Home Messages: Evolving Military Medical Practices: The podcast delves into the evolution of military medical operations in Ukraine, highlighting the lessons learned from the ongoing conflict. It emphasizes the importance of adapting medical practices to the realities of modern warfare, particularly in large-scale conflicts where traditional medical procedures may not suffice. Challenges in Battlefield Medicine: Listeners are exposed to the myriad challenges faced by medical personnel in combat zones, including the complexities of tactical combat casualty care and the necessity for rapid, autonomous decision-making under fire. The episode underscores the need for enhanced training and preparation to handle these high-pressure situations effectively. Pain Management and Medical Logistics: The discussion reveals significant hurdles in managing pain and logistics in conflict zones, with specific reference to Ukraine's current crisis. It stresses the need for reliable access to effective medications and blood supplies, highlighting the logistical challenges that can impact patient outcomes. Antimicrobial Resistance and Clinical Governance: The episode sheds light on the critical role of antibiotics in deployed medical settings and the growing concern of antimicrobial resistance. It advocates for structured guidance systems and emphasizes the importance of clinical governance to ensure high standards of care are maintained, especially when relying on NGOs and international volunteers. Data-Driven Medical Improvements: The conversation calls for the collection and analysis of medical data to enhance military medical practices. It stresses the importance of leveraging lessons learned from current conflicts to refine medical logistics, decision-making processes, and training, ensuring better preparedness for future challenges.   Episode Keywords: Military Medicine, Operational Readiness, Combat Medicine, Triage, Ukraine Conflict, Russian Invasion, Damage Control, Resuscitation, Surgery, Battlefield, Tactical Combat Casualty Care, Tourniquets, Pressure Dressings, Pain Management, Logistical Hurdles, Antimicrobial Resistance, Clinical Governance, Medical Logistics, Training, Data Analysis   Hashtags: #CombatMedicine #UkraineConflict #BattlefieldHealthcare #MilitaryMedicine #EmergencyCare #TacticalCombatCasualtyCare #FrontlineMedicine #WarfareInnovations #ConflictZoneMedicine #DrJohnQuinn   Article Citation: Quinn J et al. Prehospital Lessons From the War in Ukraine: Damage Control Resuscitation and Surgery Experiences From Point of Injury to Role 2. Mil Med. 2024 Jan 23;189(1-2):17-29. doi: 10.1093/milmed/usad253. PMID: 37647607.   Honoring the Legacy and Preserving the History of Military Medicine The WarDocs Mission is to honor the legacy, preserve the oral history, and showcase career opportunities, unique expeditionary experiences, and achievements of Military Medicine. We foster patriotism and pride in Who we are, What we do, and, most importantly, How we serve Our Patients, the DoD, and Our Nation.   Find out more and join Team WarDocs at https://www.wardocspodcast.com/ Check our list of previous guest episodes at https://www.wardocspodcast.com/our-guests Subscribe and Like our Videos on our YouTube Channel: https://www.youtube.com/@wardocspodcast Listen to the “What We Are For” Episode 47. https://bit.ly/3r87Afm   WarDocs- The Military Medicine Podcast is a Non-Profit, Tax-exempt-501(c)(3) Veteran Run Organization run by volunteers. All donations are tax-deductible and go to honoring and preserving the history, experiences, successes, and lessons learned in Military Medicine. A tax receipt will be sent to you. WARDOCS documents the experiences, contributions, and innovations of all military medicine Services, ranks, and Corps who are affectionately called "Docs" as a sign of respect, trust, and confidence on and off the battlefield,demonstrating dedication to the medical care of fellow comrades in arms.     Follow Us on Social Media Twitter: @wardocspodcast Facebook: WarDocs Podcast Instagram: @wardocspodcast LinkedIn: WarDocs-The Military Medicine Podcast YouTube Channel: https://www.youtube.com/@wardocspodcast  

Happy Friday! We're bringing you a bonus episode this Friday featuring an interview from our Times Radio afternoon show (2-4pm, Monday to Thursday). Jane and Fi speak to Dame Sally Davies, she's the UK Special Envoy on Antimicrobial Resistance and Former Chief Medical Officer for England former Chief Scientific Adviser at the Department of Health. She joins them to discuss superbugs, the state of the NHS and the future of antimicrobial resistance. The next book club pick has been announced! Eight Months on Ghazzah Street is by Hilary Mantel. If you want to contact the show to ask a question and get involved in the conversation then please email us: janeandfi@times.radioFollow us on Instagram! @janeandfiPodcast Producer: Eve SalusburyExecutive Producer: Rosie Cutler Hosted on Acast. See acast.com/privacy for more information.

When bacteria, viruses, fungi, and parasites change over time and no longer respond to medicines, it makes infections harder to treat. This increases the risk of disease spread, severe illness, and death.  Antimicrobial resistance (AMR) leads to deaths, high health treatment costs, and economic and livelihood losses. Jennifer Cohn, Director, Global Access at Global Antibiotic R&D Partnership (GARDP), joins Ray Suarez to talk about the threat of AMR, and how to prevent it. Guest: Dr. Jennifer Cohn, Director, Global Access at Global Antibiotic R&D Partnership (GARDP) Host:   Ray Suarez If you appreciate this episode and want to support the work we do, please consider making a donation to Commonwealth Club World Affairs. We cannot do this work without your help. Thank you.

In this edition of The Naked Scientists: The UK detects its first case of the new Mpox variant, but some are saying what took us so long; also the discovery of a lost city beneath the jungle canopy in Mexico; and the robots helping Cambridge scientists understand the evolution of fish... Like this podcast? Please help us by supporting the Naked Scientists

Drs. Cesar Arias (@SuperBugDoc) and Katie Barber join Dr. Julie Ann Justo (@julie_justo) to discuss what is hot-off-the-presses for gram-positive bacterial infections and it's a total party vibe! They review the latest news for recent and ongoing clinical trials (DOTS, DISRUPT, and SNAP trials), discuss hope for novel clinical tests of the cefazolin inoculum effect in staphylococci, and explore the fascinating changes in virulence and potential therapeutic options for the most challenging enterococci. Learn more about the Society of Infectious Diseases Pharmacists: https://sidp.org/About X: @SIDPharm (https://twitter.com/SIDPharm) Instagram: @SIDPharm (https://www.instagram.com/sidpharm/) Facebook: https://www.facebook.com/sidprx LinkedIn: https://www.linkedin.com/company/sidp References Climate Change and Antimicrobial Resistance. Editors in Conversation Podcast. American Society for Microbiology. Oct 2023. Is More Better? The Role of Combination Therapy for MRSA. Breakpoints Podcast Episode #30. Society of Infectious Diseases Pharmacists. Turner NA, et al. DOTS: Dalbavancin as an Option for Treatment of Staphylococcus aureus Bacteremia. ESCMID Global 2024. April 2024. NCT04775953. Real-world dalbavancin observational cohort: Rebold N, et al. Infect Dis Ther. 2024 Mar;13(3):565-579. doi: 10.1007/s40121-024-00933-2. PMID: 38427289. Exebacase DISRUPT trial : Fowler VG Jr, et al. Clin Infect Dis. 2024 Jun 14;78(6):1473-1481. doi: 10.1093/cid/ciae043. PMID: 38297916. @snap_trial tweet of Breaking News. Aug 2024. Investigator Resources for the SNAP trial. Sept 2024: https://www.snaptrial.com.au/for-investigators#interim Cefazolin inoculum effect on mortality in MSSA bacteremia : Miller WR, et al. Open Forum Infect Dis. 2018 May 23;5(6):ofy123. doi: 10.1093/ofid/ofy123. PMID: 29977970. Prevalence of cefazolin inoculum effect in MSSA and modified rapid nitrocefin test for detection: Carvajal LP, et al. Antimicrob Agents Chemother. 2024 Sep 30:e0089824. doi: 10.1128/aac.00898-24. PMID: 39345182. LiaX as surrogate for cell envelope stress in Enterococus faecium: Axell-House DB, et al. Antimicrob Agents Chemother. 2024 Mar 6;68(3):e0106923. doi: 10.1128/aac.01069-23. PMID: 38289081. Shorter is better for uncomplicated streptococcal bacteremia: Clutter DS, et al. Antimicrob Agents Chemother. 2024 Aug 7;68(8):e0022024. doi: 10.1128/aac.00220-24. PMID: 38975753. Short vs. long antibiotic duration in Streptococcus pneumoniae bacteremia: Crotty M, et al. Open Forum Infect Dis. 2024 Aug 30;11(9):ofae478. doi: 10.1093/ofid/ofae478. PMID: 39257675. This podcast is powered by Pinecast.