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Michael J. Wilkinson, M.D., F.A.C.C., F.N.L.A., explains how aligning when we eat, sleep, and move with our body's natural circadian rhythms can profoundly affect metabolic health. Drawing on research from UC San Diego and the Salk Institute, he explores how disruptions in daily patterns—late-night eating, less movement, artificial light—contribute to obesity, diabetes, and fatty liver disease. Wilkinson shows why *when* we eat may be as important as *what* or *how much* we eat, and how time-restricted eating offers a practical, biology-based strategy for preventing cardiometabolic disease and promoting healthy aging. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 41187]
In this excerpt, Dr. Natalie Marshall focuses on high intensity interval training, or HIIT. Dr. Marshall discusses the health benefits of HIIT which can be achieved in a short amount of time. Series: "Osher WISE: Well-being and Integrative Science for Everyone" [Health and Medicine] [Show ID: 41186]
In this excerpt, Dr. Natalie Marshall focuses on high intensity interval training, or HIIT. Dr. Marshall discusses the health benefits of HIIT which can be achieved in a short amount of time. Series: "Osher WISE: Well-being and Integrative Science for Everyone" [Health and Medicine] [Show ID: 41186]
Michael J. Wilkinson, M.D., F.A.C.C., F.N.L.A., responds to the question, "How long does it take to get used to Intermittent Fasting?" Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 41183]
Michael J. Wilkinson, M.D., F.A.C.C., F.N.L.A., responds to the question, "How long does it take to get used to Intermittent Fasting?" Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 41183]
Michael J. Wilkinson, M.D., F.A.C.C., F.N.L.A., responds to the question, "How long does it take to get used to Intermittent Fasting?" Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 41183]
Michael J. Wilkinson, M.D., F.A.C.C., F.N.L.A., responds to the question, "How long does it take to get used to Intermittent Fasting?" Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 41183]
Michael J. Wilkinson, M.D., F.A.C.C., F.N.L.A., responds to the question, "How long does it take to get used to Intermittent Fasting?" Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 41183]
Michael J. Wilkinson, M.D., F.A.C.C., F.N.L.A., responds to the question, "How long does it take to get used to Intermittent Fasting?" Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 41183]
Circadian timing shapes how we sleep, feel, and function each day. Satchidananda Panda, Ph.D., Salk Institute, explains that keeping daily light, meals, movement, and sleep in step with the body's internal clock supports alertness, metabolism, and recovery. Panda notes that evening light and late eating can make it harder to fall asleep and may work against healthy glucose control, while thoughtful timing of activity can improve energy and rest. He highlights that when we take medicines matters because the body's response changes across the day. Travel and shift work challenge these rhythms, but simple habits with light exposure, meal timing, and sleep can ease the strain. Panda also describes ongoing efforts testing practical routines, including limited daily eating windows paired with light and activity strategies. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40733]
Circadian timing shapes how we sleep, feel, and function each day. Satchidananda Panda, Ph.D., Salk Institute, explains that keeping daily light, meals, movement, and sleep in step with the body's internal clock supports alertness, metabolism, and recovery. Panda notes that evening light and late eating can make it harder to fall asleep and may work against healthy glucose control, while thoughtful timing of activity can improve energy and rest. He highlights that when we take medicines matters because the body's response changes across the day. Travel and shift work challenge these rhythms, but simple habits with light exposure, meal timing, and sleep can ease the strain. Panda also describes ongoing efforts testing practical routines, including limited daily eating windows paired with light and activity strategies. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40733]
Circadian timing shapes how we sleep, feel, and function each day. Satchidananda Panda, Ph.D., Salk Institute, explains that keeping daily light, meals, movement, and sleep in step with the body's internal clock supports alertness, metabolism, and recovery. Panda notes that evening light and late eating can make it harder to fall asleep and may work against healthy glucose control, while thoughtful timing of activity can improve energy and rest. He highlights that when we take medicines matters because the body's response changes across the day. Travel and shift work challenge these rhythms, but simple habits with light exposure, meal timing, and sleep can ease the strain. Panda also describes ongoing efforts testing practical routines, including limited daily eating windows paired with light and activity strategies. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40733]
Circadian timing shapes how we sleep, feel, and function each day. Satchidananda Panda, Ph.D., Salk Institute, explains that keeping daily light, meals, movement, and sleep in step with the body's internal clock supports alertness, metabolism, and recovery. Panda notes that evening light and late eating can make it harder to fall asleep and may work against healthy glucose control, while thoughtful timing of activity can improve energy and rest. He highlights that when we take medicines matters because the body's response changes across the day. Travel and shift work challenge these rhythms, but simple habits with light exposure, meal timing, and sleep can ease the strain. Panda also describes ongoing efforts testing practical routines, including limited daily eating windows paired with light and activity strategies. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40733]
Circadian timing shapes how we sleep, feel, and function each day. Satchidananda Panda, Ph.D., Salk Institute, explains that keeping daily light, meals, movement, and sleep in step with the body's internal clock supports alertness, metabolism, and recovery. Panda notes that evening light and late eating can make it harder to fall asleep and may work against healthy glucose control, while thoughtful timing of activity can improve energy and rest. He highlights that when we take medicines matters because the body's response changes across the day. Travel and shift work challenge these rhythms, but simple habits with light exposure, meal timing, and sleep can ease the strain. Panda also describes ongoing efforts testing practical routines, including limited daily eating windows paired with light and activity strategies. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40733]
Circadian timing shapes how we sleep, feel, and function each day. Satchidananda Panda, Ph.D., Salk Institute, explains that keeping daily light, meals, movement, and sleep in step with the body's internal clock supports alertness, metabolism, and recovery. Panda notes that evening light and late eating can make it harder to fall asleep and may work against healthy glucose control, while thoughtful timing of activity can improve energy and rest. He highlights that when we take medicines matters because the body's response changes across the day. Travel and shift work challenge these rhythms, but simple habits with light exposure, meal timing, and sleep can ease the strain. Panda also describes ongoing efforts testing practical routines, including limited daily eating windows paired with light and activity strategies. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40733]
Circadian timing shapes how we sleep, feel, and function each day. Satchidananda Panda, Ph.D., Salk Institute, explains that keeping daily light, meals, movement, and sleep in step with the body's internal clock supports alertness, metabolism, and recovery. Panda notes that evening light and late eating can make it harder to fall asleep and may work against healthy glucose control, while thoughtful timing of activity can improve energy and rest. He highlights that when we take medicines matters because the body's response changes across the day. Travel and shift work challenge these rhythms, but simple habits with light exposure, meal timing, and sleep can ease the strain. Panda also describes ongoing efforts testing practical routines, including limited daily eating windows paired with light and activity strategies. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40733]
Focused ultrasound (FUS), also called high-intensity focused ultrasound (HIFU), is a noninvasive treatment using sound waves to address essential tremor and tremor-dominant Parkinson's disease. Drs. Doris Wang and Leo Sugrue of UCSF explain how FUS and deep brain stimulation work to reduce tremor, outline which patients may benefit, and describe how the UCSF team individualizes treatment. Series: "UC San Francisco News" [Health and Medicine] [Show ID: 41035]
Focused ultrasound (FUS), also called high-intensity focused ultrasound (HIFU), is a noninvasive treatment using sound waves to address essential tremor and tremor-dominant Parkinson's disease. Drs. Doris Wang and Leo Sugrue of UCSF explain how FUS and deep brain stimulation work to reduce tremor, outline which patients may benefit, and describe how the UCSF team individualizes treatment. Series: "UC San Francisco News" [Health and Medicine] [Show ID: 41035]
Focused ultrasound (FUS), also called high-intensity focused ultrasound (HIFU), is a noninvasive treatment using sound waves to address essential tremor and tremor-dominant Parkinson's disease. Drs. Doris Wang and Leo Sugrue of UCSF explain how FUS and deep brain stimulation work to reduce tremor, outline which patients may benefit, and describe how the UCSF team individualizes treatment. Series: "UC San Francisco News" [Health and Medicine] [Show ID: 41035]
Danielle K. Glorioso, LCSW, examines resilience as a skill that can be strengthened. Glorioso explores the many health benefits of resilient behavior. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 41123]
Danielle K. Glorioso, LCSW, examines resilience as a skill that can be strengthened. Glorioso explores the many health benefits of resilient behavior. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 41123]
Danielle K. Glorioso, LCSW, examines resilience as a skill that can be strengthened. Glorioso explores the many health benefits of resilient behavior. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 41123]
Danielle K. Glorioso, LCSW, examines resilience as a skill that can be strengthened. Glorioso explores the many health benefits of resilient behavior. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 41123]
Danielle K. Glorioso, LCSW, examines resilience as a skill that can be strengthened. Glorioso explores the many health benefits of resilient behavior. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 41123]
Danielle K. Glorioso, LCSW, examines resilience as a skill that can be strengthened. Glorioso explores the many health benefits of resilient behavior. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 41123]
Founded in 1975, UCSF Fresno commemorates 50 remarkable years of training local doctors and improving healthcare in California's Central Valley in 2025. UCSF Fresno is a regional campus of UCSF's School of Medicine, located in the heart of California's San Joaquin Valley. By both serving and drawing strength from extraordinarily deep community roots, UCSF Fresno brings critical health care to families while to growing the next generation of health care providers and researchers. [Health and Medicine] [Show ID: 40987]
Founded in 1975, UCSF Fresno commemorates 50 remarkable years of training local doctors and improving healthcare in California's Central Valley in 2025. UCSF Fresno is a regional campus of UCSF's School of Medicine, located in the heart of California's San Joaquin Valley. By both serving and drawing strength from extraordinarily deep community roots, UCSF Fresno brings critical health care to families while to growing the next generation of health care providers and researchers. [Health and Medicine] [Show ID: 40987]
Founded in 1975, UCSF Fresno commemorates 50 remarkable years of training local doctors and improving healthcare in California's Central Valley in 2025. UCSF Fresno is a regional campus of UCSF's School of Medicine, located in the heart of California's San Joaquin Valley. By both serving and drawing strength from extraordinarily deep community roots, UCSF Fresno brings critical health care to families while to growing the next generation of health care providers and researchers. [Health and Medicine] [Show ID: 40987]
Urinary incontinence and sexual dysfunction are common side effects of prostate cancer treatment, but both are manageable. Dr. Lindsay Hampson explains the types of incontinence—stress, urge, mixed, and overflow—and how identifying the cause guides treatment. Management strategies include pelvic floor physical therapy, medications, and surgical options like slings or artificial urinary sphincters. For sexual dysfunction, approaches range from oral medications and vacuum devices to injections and implants. Dr. Michael Rabow also highlights the side effects of androgen deprivation therapy, including fatigue, depression, hot flashes, and cardiovascular risk. He outlines evidence-based strategies—like exercise, cognitive behavioral therapy, and medications—to help preserve well-being and quality of life during treatment. Series: "Prostate Cancer Patient Conference" [Health and Medicine] [Show ID: 40869]
Urinary incontinence and sexual dysfunction are common side effects of prostate cancer treatment, but both are manageable. Dr. Lindsay Hampson explains the types of incontinence—stress, urge, mixed, and overflow—and how identifying the cause guides treatment. Management strategies include pelvic floor physical therapy, medications, and surgical options like slings or artificial urinary sphincters. For sexual dysfunction, approaches range from oral medications and vacuum devices to injections and implants. Dr. Michael Rabow also highlights the side effects of androgen deprivation therapy, including fatigue, depression, hot flashes, and cardiovascular risk. He outlines evidence-based strategies—like exercise, cognitive behavioral therapy, and medications—to help preserve well-being and quality of life during treatment. Series: "Prostate Cancer Patient Conference" [Health and Medicine] [Show ID: 40869]
Psychological resilience in later life examines how older adults adapt after adversity and cultivate everyday practices that sustain well-being and purpose.Elizabeth W. Twamley, Ph.D., introduces and guides a discussion on mental health and resilience among older adults. Ellen E. Lee, M.D., characterizes resilience as dynamic learning oriented toward flourishing and urges a low threshold for seeking help when symptoms overwhelm daily routines. Sidney Zisook, M.D., presents grief as adaptation to loss, distinguishes acute from integrated grief, and explains how intense waves of emotion gradually become less frequent and more manageable; he views psychedelic therapies as promising but not ready for routine treatment. Marti E. Kranzberg shares practical approaches that include mindfulness, journaling, gratitude, movement, sleep, pain management, creative arts, time in nature, community, and purpose. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40963]
Psychological resilience in later life examines how older adults adapt after adversity and cultivate everyday practices that sustain well-being and purpose.Elizabeth W. Twamley, Ph.D., introduces and guides a discussion on mental health and resilience among older adults. Ellen E. Lee, M.D., characterizes resilience as dynamic learning oriented toward flourishing and urges a low threshold for seeking help when symptoms overwhelm daily routines. Sidney Zisook, M.D., presents grief as adaptation to loss, distinguishes acute from integrated grief, and explains how intense waves of emotion gradually become less frequent and more manageable; he views psychedelic therapies as promising but not ready for routine treatment. Marti E. Kranzberg shares practical approaches that include mindfulness, journaling, gratitude, movement, sleep, pain management, creative arts, time in nature, community, and purpose. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40963]
Psychological resilience in later life examines how older adults adapt after adversity and cultivate everyday practices that sustain well-being and purpose.Elizabeth W. Twamley, Ph.D., introduces and guides a discussion on mental health and resilience among older adults. Ellen E. Lee, M.D., characterizes resilience as dynamic learning oriented toward flourishing and urges a low threshold for seeking help when symptoms overwhelm daily routines. Sidney Zisook, M.D., presents grief as adaptation to loss, distinguishes acute from integrated grief, and explains how intense waves of emotion gradually become less frequent and more manageable; he views psychedelic therapies as promising but not ready for routine treatment. Marti E. Kranzberg shares practical approaches that include mindfulness, journaling, gratitude, movement, sleep, pain management, creative arts, time in nature, community, and purpose. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40963]
Psychological resilience in later life examines how older adults adapt after adversity and cultivate everyday practices that sustain well-being and purpose.Elizabeth W. Twamley, Ph.D., introduces and guides a discussion on mental health and resilience among older adults. Ellen E. Lee, M.D., characterizes resilience as dynamic learning oriented toward flourishing and urges a low threshold for seeking help when symptoms overwhelm daily routines. Sidney Zisook, M.D., presents grief as adaptation to loss, distinguishes acute from integrated grief, and explains how intense waves of emotion gradually become less frequent and more manageable; he views psychedelic therapies as promising but not ready for routine treatment. Marti E. Kranzberg shares practical approaches that include mindfulness, journaling, gratitude, movement, sleep, pain management, creative arts, time in nature, community, and purpose. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40963]
Psychological resilience in later life examines how older adults adapt after adversity and cultivate everyday practices that sustain well-being and purpose.Elizabeth W. Twamley, Ph.D., introduces and guides a discussion on mental health and resilience among older adults. Ellen E. Lee, M.D., characterizes resilience as dynamic learning oriented toward flourishing and urges a low threshold for seeking help when symptoms overwhelm daily routines. Sidney Zisook, M.D., presents grief as adaptation to loss, distinguishes acute from integrated grief, and explains how intense waves of emotion gradually become less frequent and more manageable; he views psychedelic therapies as promising but not ready for routine treatment. Marti E. Kranzberg shares practical approaches that include mindfulness, journaling, gratitude, movement, sleep, pain management, creative arts, time in nature, community, and purpose. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40963]
Psychological resilience in later life examines how older adults adapt after adversity and cultivate everyday practices that sustain well-being and purpose.Elizabeth W. Twamley, Ph.D., introduces and guides a discussion on mental health and resilience among older adults. Ellen E. Lee, M.D., characterizes resilience as dynamic learning oriented toward flourishing and urges a low threshold for seeking help when symptoms overwhelm daily routines. Sidney Zisook, M.D., presents grief as adaptation to loss, distinguishes acute from integrated grief, and explains how intense waves of emotion gradually become less frequent and more manageable; he views psychedelic therapies as promising but not ready for routine treatment. Marti E. Kranzberg shares practical approaches that include mindfulness, journaling, gratitude, movement, sleep, pain management, creative arts, time in nature, community, and purpose. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40963]
Danielle K. Glorioso, LCSW, explores the complex nature of grief, emphasizing that it is a lifelong, evolving response to loss rather than something to “get over.” She explains the differences between acute grief, integrated grief, and prolonged grief disorder. Drawing on both professional expertise and personal loss, Glorioso offers practical strategies for coping, supporting others, and finding hope while honoring the memory of loved ones. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 41121]
Danielle K. Glorioso, LCSW, explores the complex nature of grief, emphasizing that it is a lifelong, evolving response to loss rather than something to “get over.” She explains the differences between acute grief, integrated grief, and prolonged grief disorder. Drawing on both professional expertise and personal loss, Glorioso offers practical strategies for coping, supporting others, and finding hope while honoring the memory of loved ones. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 41121]
Danielle K. Glorioso, LCSW, explores the complex nature of grief, emphasizing that it is a lifelong, evolving response to loss rather than something to “get over.” She explains the differences between acute grief, integrated grief, and prolonged grief disorder. Drawing on both professional expertise and personal loss, Glorioso offers practical strategies for coping, supporting others, and finding hope while honoring the memory of loved ones. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 41121]
Danielle K. Glorioso, LCSW, explores the complex nature of grief, emphasizing that it is a lifelong, evolving response to loss rather than something to “get over.” She explains the differences between acute grief, integrated grief, and prolonged grief disorder. Drawing on both professional expertise and personal loss, Glorioso offers practical strategies for coping, supporting others, and finding hope while honoring the memory of loved ones. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 41121]
Danielle K. Glorioso, LCSW, explores the complex nature of grief, emphasizing that it is a lifelong, evolving response to loss rather than something to “get over.” She explains the differences between acute grief, integrated grief, and prolonged grief disorder. Drawing on both professional expertise and personal loss, Glorioso offers practical strategies for coping, supporting others, and finding hope while honoring the memory of loved ones. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 41121]
Cognitive resilience grows from small, consistent habits that keep the brain adaptable. Fadel Zeidan, Ph.D., frames mindfulness as mental training that improves attention, processing, and the way people relate to pain. Erin E. Sundermann, Ph.D., underscores modifiable pathways to healthier aging, highlighting movement, social connection, hearing support, and lifelong learning as mutually reinforcing drivers of brain health. Raenne C. Moore, Ph.D., centers practical strategies that translate into daily life, including routines, planned breaks, reducing distractions, and attending to anxiety or depression. Carolyn Dunmore, an older adult community Mmmber, exemplifies resilience through steady activity, purposeful community roles, faith, self-compassion, and the “use it or lose it” mindset. Together, Zeidan, Sundermann, Moore, and Dunmore point to a clear theme: everyday practices accumulate to support memory, attention, and well-being as people age. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40962]
Cognitive resilience grows from small, consistent habits that keep the brain adaptable. Fadel Zeidan, Ph.D., frames mindfulness as mental training that improves attention, processing, and the way people relate to pain. Erin E. Sundermann, Ph.D., underscores modifiable pathways to healthier aging, highlighting movement, social connection, hearing support, and lifelong learning as mutually reinforcing drivers of brain health. Raenne C. Moore, Ph.D., centers practical strategies that translate into daily life, including routines, planned breaks, reducing distractions, and attending to anxiety or depression. Carolyn Dunmore, an older adult community Mmmber, exemplifies resilience through steady activity, purposeful community roles, faith, self-compassion, and the “use it or lose it” mindset. Together, Zeidan, Sundermann, Moore, and Dunmore point to a clear theme: everyday practices accumulate to support memory, attention, and well-being as people age. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40962]
Cognitive resilience grows from small, consistent habits that keep the brain adaptable. Fadel Zeidan, Ph.D., frames mindfulness as mental training that improves attention, processing, and the way people relate to pain. Erin E. Sundermann, Ph.D., underscores modifiable pathways to healthier aging, highlighting movement, social connection, hearing support, and lifelong learning as mutually reinforcing drivers of brain health. Raenne C. Moore, Ph.D., centers practical strategies that translate into daily life, including routines, planned breaks, reducing distractions, and attending to anxiety or depression. Carolyn Dunmore, an older adult community Mmmber, exemplifies resilience through steady activity, purposeful community roles, faith, self-compassion, and the “use it or lose it” mindset. Together, Zeidan, Sundermann, Moore, and Dunmore point to a clear theme: everyday practices accumulate to support memory, attention, and well-being as people age. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40962]
Cognitive resilience grows from small, consistent habits that keep the brain adaptable. Fadel Zeidan, Ph.D., frames mindfulness as mental training that improves attention, processing, and the way people relate to pain. Erin E. Sundermann, Ph.D., underscores modifiable pathways to healthier aging, highlighting movement, social connection, hearing support, and lifelong learning as mutually reinforcing drivers of brain health. Raenne C. Moore, Ph.D., centers practical strategies that translate into daily life, including routines, planned breaks, reducing distractions, and attending to anxiety or depression. Carolyn Dunmore, an older adult community Mmmber, exemplifies resilience through steady activity, purposeful community roles, faith, self-compassion, and the “use it or lose it” mindset. Together, Zeidan, Sundermann, Moore, and Dunmore point to a clear theme: everyday practices accumulate to support memory, attention, and well-being as people age. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40962]
Targeting the biology of aging offers a path to stronger resilience and longer health. John C. Newman, M.D., Ph.D., explains that aging arises from measurable cellular processes, often called hallmarks of aging, including changes involving mitochondria, stem cells, cellular senescence, inflammation, and protein quality control. Newman describes how basic science in model organisms reveals mechanisms that can be manipulated to extend healthy lifespan and guide therapies. Emerging approaches aim either to strengthen stress responses that make cells more resilient or to address downstream consequences. Many clinical studies across the country now test interventions that target aging, supported by national efforts to standardize methods and expand training. Newman also investigates ketone bodies as energy sources that influence inflammation, muscle preservation, and other processes relevant to frailty and recovery. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40961]
Targeting the biology of aging offers a path to stronger resilience and longer health. John C. Newman, M.D., Ph.D., explains that aging arises from measurable cellular processes, often called hallmarks of aging, including changes involving mitochondria, stem cells, cellular senescence, inflammation, and protein quality control. Newman describes how basic science in model organisms reveals mechanisms that can be manipulated to extend healthy lifespan and guide therapies. Emerging approaches aim either to strengthen stress responses that make cells more resilient or to address downstream consequences. Many clinical studies across the country now test interventions that target aging, supported by national efforts to standardize methods and expand training. Newman also investigates ketone bodies as energy sources that influence inflammation, muscle preservation, and other processes relevant to frailty and recovery. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40961]
Healthy aging starts with physical resilience, the body's ability to withstand and recover from stress. Maile Young Karris, M.D., defines the concept and sets the stage for practical strategies that match real-world needs. Ryan J. Moran, M.D., M.P.H., recommends simple routines such as wall push ups, posture alignment, and chin tucks, and he links posture and vision to fall prevention; social connection helps people stick with movement. Theodore Chan, M.D., F.A.C.E.P., F.A.A.E.M., explains that age alone is a poor predictor of outcomes in acute care and that functional resilience strongly influences decisions. Gail Levine emphasizes accountability, community, and balanced nutrition. Moran highlights protein needs of about 1 to 1.2 grams per kilogram plus calcium with possible vitamin D, and he favors plant focused eating with limited processed foods. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40960]
Healthy aging starts with physical resilience, the body's ability to withstand and recover from stress. Maile Young Karris, M.D., defines the concept and sets the stage for practical strategies that match real-world needs. Ryan J. Moran, M.D., M.P.H., recommends simple routines such as wall push ups, posture alignment, and chin tucks, and he links posture and vision to fall prevention; social connection helps people stick with movement. Theodore Chan, M.D., F.A.C.E.P., F.A.A.E.M., explains that age alone is a poor predictor of outcomes in acute care and that functional resilience strongly influences decisions. Gail Levine emphasizes accountability, community, and balanced nutrition. Moran highlights protein needs of about 1 to 1.2 grams per kilogram plus calcium with possible vitamin D, and he favors plant focused eating with limited processed foods. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40960]
Dr. Rahul Aggarwal presents emerging treatments for advanced prostate cancer, highlighting rapid advances in drug development. He outlines therapies targeting cancer cell surface proteins beyond PSMA, including CD46, B7-H3, and DLL3, and explains how antibody-drug conjugates deliver potent chemotherapy directly to tumors. He also discusses bispecific T-cell engagers designed to trigger immune attacks on cancer cells, including promising results from agents like Talquetamab. Aggarwal explores new isotopes such as actinium-225 for radioligand therapy, which may offer stronger and more durable responses than current treatments. He emphasizes continued innovation in targeting the androgen receptor, with drugs that degrade the receptor or block androgen production more effectively than existing therapies. Series: "Prostate Cancer Patient Conference" [Health and Medicine] [Show ID: 40813]