Podcasts about methods one

Co-hosts Bob Graham and Tom Brush discuss the benefits and drawbacks of one-to-many follow-up, including emails, advertisements and other means. Stay tuned toward the end when they provide their one thing, their today's antidote, which will help you better address one-to-many follow-up. --- Support this podcast: https://podcasters.spotify.com/pod/show/renegade-success-network/support

Co-hosts Tom Brush and Bob Graham delve into the what and why of one-on-one follow-up. They explore its benefits, potential drawbacks, and how to determine when one-on-one follow-up makes the most sense. Stay tuned toward the end of the program when they share their today's antidotes, that one thing you can consider as you think through one-on-one follow-up. Visit http://RenegadeSuccessNetwork.com to discover more about how they help business leaders, owners, entrepreneurs and nonprofit professionals find their own unique pathway to success. --- Support this podcast: https://podcasters.spotify.com/pod/show/renegade-success-network/support

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.06.24.170019v1?rss=1 Authors: Naim-Feil, J., Peled, A., Freche, D., Hess, S., Grinshpoon, A., Levit-Binnun, N., Moses, E. Abstract: Background: Altered stimuli processing is a key feature of schizophrenia. Application of concurrent transcranial magnetic stimulation (TMS) with electroencephalography (TMS-EEG) is an effective stimulus which allows direct measurement of the cortical response within a millisecond time resolution. Test-retest TMS-EEG studies present evidence of high reproducibility in healthy controls (HC), however, this stability of response has not been examined in schizophrenia. Objective: The current study maps TMS-evoked patterns of cortical excitability in schizophrenia and examine whether these cortical patterns are amenable to change as symptoms of schizophrenia improve. Methods: One hundred single-pulse TMS and 100 sham pulses were applied to frontal regions of 19 schizophrenia in-patients and 26 HC while electroencephalography data were simultaneously acquired. Medication and schizophrenia symptoms were reported. This protocol was repeated across three sessions (1 week apart) for each participant. The TMS-evoked cortical response of each participant was averaged and compared between groups. Results: Schizophrenia patients showed reduced cortical excitability at early time-windows and increased excitability at later time-windows. Increased excitability at later windows was associated with heightened symptom severity. Schizophrenia patients showed an increased variability in cortical response over sessions relative to HC. Increased change in cortical response from session 1 to session 3 correlated with symptom improvement. Conclusions: Schizophrenia patients presented with abnormal patterns of cortical excitability when processing TMS stimuli. These dynamic patterns of cortical response were amenable to change as symptoms of schizophrenia improved. Further research into electrophysiological biomarkers of symptom improvement is hoped to improve current diagnosis and treatment models of schizophrenia. Copy rights belong to original authors. Visit the link for more info

Persuasion, Passion, Power & Practice - Four modes of evangelism…

Connector ConfusionCongratulations to our Slack member Mobius Striptease! Mobius’ pulse generator won first place at their Senior Design Expo!Article written about MacroFab: Houston electronics manufacturing company gears up for growth. Talks about the growth of MacroFab over the past 2 years.ParkerRPI3 Compute ModulePCM5122 RoutedLAN9514 Routedsingle upstream USB port on BCM2835Pin 44 Ethernet 25MHz outputPin 31 LAN RESETInformation found on the Raspberry pi forumNeed to add USB current limitingCM3 HOMEGuido Ottaviani made his own carrier board I have been looking at for inspiration to solve some of the final problems1473149-4Connector being used to socket the RPI3 Compute ModuleStephenCrazy EQ amplifier design continuationOpted to go with a card edge solution for each EQ bandEach band connects via a 36 pin PCI-Express connector+12V-12V+5v Reference-5V referenceGnd4 In SignalsCutBoostPotentiometer pin 221 modules in total. 1 module has all of the power and main signal in/out from the amp. This sends all of the other modules their power/ground and signals.Need to rethink things - Feedback loops are crappy.. Need to go with a 64 pin solution20 ins and 20 outsBeveled edges and Hard Gold plating discussion in a future episodeR.F.O.Debugging I²C with HardwareI²CDriver is a crowdfunded effort by James BowmanOpen Source tool used to easily drive I2C devicesControls with a GUI, command-line, C and C++ using a single source file, or Python 2 and 3, using a moduleLow Cost Reverse Polarity and Over Current ProtectionJeri Ellsworth's new video on reverse bias protectionHas a Robbie Robot on her desk!Methods“One of the options is to do nothing”Diode inputExploding DiodePMOS FETLow rds on - “almost not there”Body Diode - Watch out for thisVisit our Public Slack Channel and join the conversation in between episodes!Tags: 1473149-4, 20-Band, CM3 Home, electronics podcast, EQ, i2c, Jeri Ellsworth, LAN9514, MacroFab, macrofab engineering podcast, Mobius Striptease, PCM5122, Reverse Polarity, Reverse Polarity Protection

Background and Objectives: The Pain Sensitivity Questionnaire (PSQ) is predictive of pain-related responses to experimental stimuli in German-speaking individuals. Here, we explored the validation of the English translation of the PSQ (PSQ-E). Methods: One hundred thirty-six patients scheduled to undergo a low back interventional procedure completed the PSQ-E and other questionnaires including the Brief Pain Inventory. Pain ratings on a visual analog scale (VAS) were obtained following 2 standardized injections of subcutaneous lidocaine (VAS 1, infiltration in hand; VAS 2, infiltration of procedural site). The VAS measures were compared with the PSQ-E data and other inventories using linear regression analysis with stepwise selection of variables. Results: The PSQ-E properties were in all respects similar to those of the original German PSQ. VAS 1 magnitude was predicted by PSQ-E-minor (r = 0.26, P < 0.01). VAS 2 magnitude was predicted by PSQ-E-minor (r = 0.34, P < 0.001), and the prediction was significantly enhanced by further inclusion of the Brief Pain Inventory interference score (total r = 0.40, P < 0.001). Conclusions: The study demonstrated that a significant correlation exists between the PSQ-E and clinically relevant pain ratings. This study validates the PSQ-E both in terms of measuring pain sensitivity and as possible means of recognizing patients with high pain sensitivity. Defining this subset of patients may have clinical utility in the future.

Purpose: To describe new details of epiretinal cell proliferation in flat-mounted internal limiting membrane specimens. Methods: One hundred nineteen internal limiting membrane specimens were removed en bloc with epiretinal membranes from 79 eyes with macular pucker (MP) and 40 eyes with vitreomacular traction syndrome. Intraoperatively, posterior vitreous detachment was assessed as complete or incomplete. Whole specimens were flat-mounted on glass slides and processed for interference and phase-contrast microscopy, cell viability assay, and immunocytochemistry. Results: Mean cell viability percentage was higher in MP than in vitreomacular traction syndrome. Two cell distribution patterns were found. Anti-CD163 labeling presented predominantly in MP with complete posterior vitreous detachment. CD45 expression was similar in all groups of diagnosis. Anti-glial fibrillary acidic protein (GFAP) labeling was found in MP irrespective of the extent of posterior vitreous detachment. Alpha-SMA (alpha-smooth muscle actin) labeling was mainly presented in MP with incomplete posterior vitreous detachment and in vitreomacular traction syndrome. Simultaneous antibody labeling included GFAP/CD45, GFAP/CD163, CD163/CD45, and CD163/alpha-SMA. Conclusion: Hyalocytes constitute a major cell type of epiretinal cell proliferation in eyes with MP and vitreomacular traction syndrome. Glial cells, notably retinal Muller cells, are involved as well. It appears that transdifferentiation of cells in vitreomacular traction might be more frequent than previously thought and that those cells possess a greater variability of immunocytochemical properties than expected. RETINA 33:77-88, 2013

Background: Despite the notion that randomized controlled trials are regarded as the gold standard in psychotherapy research, questions about their generalizability have been raised. This paper focuses on the differences between participants and eligible nonparticipants of a randomized controlled trial for patients with borderline personality disorder (BPD). Sampling and Methods: One hundred forty-two patients were screened, and 122 were found eligible for study participation. Out of these, 64 patients (52.5%) gave informed consent and were included in the study. Results: The 58 eligible nonparticipants showed a lower level of functioning (global assessment of functioning score), had a history of more outpatient treatment attempts and were living alone more often. Regarding acute symptoms and severity of BPD as indexed by suicide attempts, inpatient treatments, substance abuse and history of trauma, no differences between the groups could be detected. Moreover, participants showed significantly more eating disorders, whereas nonparticipants presented more affective and anxiety disorders. Conclusions: The results indicate that lower psychosocial functioning and comorbid affective and anxiety disorders decrease BPD patients' willingness to participate in an RCT. Copyright (C) 2010 S. Karger AG, Basel

Objective: Impulsive behavior in alcoholics puts them at serious risk of severer course of disease and has been related to the serotonergic neurotransmission dysfunction. The aim of this study is to investigate the association between impulsive aggression in alcohol dependents with regard to the G-1438A polymorphism in the promoter region of the 5-HT2A receptor gene. Furthermore, we investigated the statistical interaction between 5-HT2A alleles, antisocial personality disorder (APD) and impulsive aggression in alcohol dependents. Alcohol dependents were investigated because these personality disorders and impulsive behavior are very frequent in alcohol dependence anf of clinical relevance. Methods: One hundred and thirty-five patients of German descent meeting DSM-IV criteria of alcohol dependence were recruited. Blood samples were taken from alcohol dependents to determine 5-HT2A promoter polymorphisms using PCR (polymerase chain reaction) of lymphocyte DNA. Impulsive aggression was assessed using a German version of the Barratt Impulsiveness Scale which was translated and backtranslated. Alcohol dependents were subdivided into low- or high-impulsivity groups using a median split of the Barratt score. APD and borderline personality disorder (BPD) were assessed using the SCID-II interview. Results: The low-impulsivity group was slightly older and showed a later age at alcoholism onset than the highly impulsive group. Alcohol dependents with high impulsive traits showed a significant association with 5-HT2A 1438 A alleles. After excluding alcohol dependents with APD or BPD from the analysis, this association remained significant. Furthermore, no association between APD, BPD and 5-HT2A alleles was noted. Conclusions: Inpatient alcohol dependents showed a significant association between 5-HT2A A alleles and impulsive traits, independent of the presence of APD or BPD. No association was noted between personality disorders and the polymorphism. This is the first report about an association of 5-HT2A promoter polymorphism and impulsive behavior in alcohol dependents. This finding may refer only to impulsive traits and may be independent of personality disorders in this sample. These results have to be confirmed in larger samples and in healthy control subjects to determine whether this association is of general validity. Copyright (C) 2001 S. Karger AG, Basel.

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.04.20.050799v1?rss=1 Authors: Jeong, T. S., Yee, G. T., Lim, T. G., Kim, W. K., Yoo, C. J. Abstract: Background Decompressive craniectomy is an important surgical treatment for patients with severe traumatic brain injury (TBI). Several reports have been published on the efficacy of non-watertight sutures in duraplasty performed in decompressive craniectomy. This study aims to evaluate the effectiveness of dura closure without sutures (non-suture duraplasty) in decompressive craniectomy for TBI. Methods One hundred and six patients were enrolled at a single trauma center between January 2017 and December 2018. We retrospectively collected the data and classified the patients into non-suture and suture duraplasty craniectomy groups. We compared the characteristics of patients and their intra/post-operative findings such as operative time, blood loss, imaging findings, complications, and Glasgow outcome scale. Results There were 37 patients in the non-suture group and 69 in the suture craniectomy group. There were no significant differences between the two groups with regard to general characteristics. The operative time was 205 min for the suture duraplasty group and 150 min for the non-suture duraplasty group, and that for the non-suture duraplasty group was significantly lesser (p=0.002). Blood loss was significantly lesser in the non-suture duraplasty group (1000 mL) than in the suture duraplasty group (1500 mL, p=0.028). There were no other significant differences. Conclusion Non-suture duraplasty involved shorter operative time and lesser blood loss when compared to suture duraplasty. Other complications and prognosis were similar in both groups. Therefore, it can be concluded that decompressive craniectomy with non-suture duraplasty is a safe and useful surgical technique in patients with TBI. Copy rights belong to original authors. Visit the link for more info