Podcasts about Variability

Why do two people with Parkinson's experience the disease so differently?In this episode, we sit down with researchers Patrik Verstreken and Natalie Kaempf to explore groundbreaking work that may help answer that question. Using advanced biology, biomarkers, and artificial intelligence, their team has identified what could be five distinct biological subtypes of Parkinson's disease.We discuss what these findings mean for people living with Parkinson's today, how genetics and environmental factors may influence disease progression, and why understanding the biology behind Parkinson's could lead to more personalized treatments, better clinical trials, and earlier diagnosis in the future.Chapters00:00 Introduction to Parkinson's Disease Research02:54 Understanding the Variability of Parkinson's Disease06:07 Symptomatic Treatments vs. Underlying Causes08:57 Subtypes of Parkinson's Disease11:51 The Role of Biomarkers in Early Diagnosis14:46 AI's Impact on Parkinson's Research18:10 Clinical Trials and Treatment Stratification20:59 Future Directions in Parkinson's Disease Treatment23:55 The Importance of Community and Hope

Constraints on the complete optimization of human motion Glazier PS, Davids K. Sports Med. 2009;39(1):15-28. doi:10.2165/00007256-200939010-00002 Due to copyright laws, unless the article is open source we cannot legally post the PDF on the website for the world to download at will. Brought to you by our sponsors at: CSMi – https://www.humacnorm.com/ptinquest VALD MoveHealth - https://movehealth.me/ Learn more about/purchase our courses: The Science PT | Dungeons & Dynamometers Support us on the Patreons! Music for PT Inquest: "The Science of Selling Yourself Short" by Less Than Jake Used by Permission Other Music by Kevin MacLeod – incompetech.com: MidRoll Promo – Mining by Moonlight Koal Challenge – Sam Roux  

A few revelations I have had from doing PT and S&C workshops with water bags. Why is adapting to increased variability typically better than adapting to increased load or pain? http://perceptionaction.com/ My Research Gate Page (pdfs of my articles) My ASU Web page Podcast Facebook page (videos, pics, etc)   Subscribe in iOS/Apple Subscribe in Anroid/Google   Support the podcast and receive bonus content   Credits: The Flamin' Groovies – ShakeSome Action Mark Lanegan - Saint Louis Elegy via freemusicarchive.org and jamendo.com

Rising temperatures and more frequent heat events are putting pressure on apple production across the Pacific Northwest. With more frequent heat events in the PNW, protecting fruit quality starts early.

Sponsor Link:This episode of Space Nuts is brought to you by NordVPN, your trusted partner for online security. To access our exclusive offer, including four extra months for free, visit www.nordvpn.com/spacenuts.Cosmic Queries: Unraveling Stellar Mysteries In this enlightening Q&A episode of Space Nuts, hosts Andrew Dunkley and Professor Jonti Horner tackle a trio of intriguing questions from listeners. From the complexities of hydrogen fusion to the potential for life in Martian caves and the mysteries of stellar activity, this episode is a deep dive into the cosmos.Episode Highlights:- Hydrogen to Helium Fusion: Ken from Maroochydore seeks clarity on the fusion process in stars, questioning why the mass of helium appears greater than the sum of its hydrogen components. Jonty explains the concept of binding energy and how it plays a crucial role in energy production during fusion, demystifying this fundamental stellar process.- Caves on Mars: Mark from Brisbane wonders about the possibility of limestone caves on Mars and whether they could support life with a stable atmosphere. The hosts discuss the geological differences between Earth and Mars, the challenges of oxygen presence, and the implications for future human habitation in Martian caves.- Understanding Stellar Activity: Casey from Colorado inquires about the changing activity levels of stars and solar cycles. Jonty elaborates on the magnetic forces driving solar cycles, the variability of different stars, and the fascinating world of asteroseismology, revealing how stars can change over time and what that means for our understanding of the universe.For more Space Nuts, including our continuously updating newsfeed and to listen to all our episodes, visit our website. Follow us on social media at SpaceNutsPod on Facebook, Instagram, and more. We love engaging with our community, so be sure to drop us a message or comment on your favourite platform.If you'd like to help support Space Nuts and join our growing family of insiders for commercial-free episodes and more, visit spacenutspodcast.com/about.Stay curious, keep looking up, and join us next time for more stellar insights and cosmic wonders. Until then, clear skies and happy stargazing.Become a supporter of this podcast: https://www.spreaker.com/podcast/space-nuts-astronomy-insights-cosmic-discoveries--2631155/support.- Introduction to Hydrogen Fusion- The Binding Energy Explained- Potential for Life in Martian Caves- The Nature of Stellar Activity- Understanding Solar Cycles and Variability

How can school leaders move beyond traditional instruction to truly center the needs of every student? In this episode, we sit down with two visionary principals from San Diego: Andrea Pino-Antl of Creative Performing and Media Arts and Jennifer Chien of Casita Center for Technology, Science, and Math. Listen as we dive into a candid conversation about overcoming the fixed mindset in math instruction and explore the specific strategies and tools that support students who learn differently. From fostering a culture of belonging to practical advice for fellow administrators, Andrea and Jennifer share how they are turning learner variability into a school-wide strength. Access the full podcast transcript at tinyurl.com/DeepDive-SanDiego   

-The Run Down By The Running Effect (our new newsletter!): https://tinyurl.com/mr36s9rsThe myths runners live by are surprisingly hard to kill. Alex Ostberg is back with Dominic to dismantle four more of them.First up: the soft surface myth. Alex explains how the brain anticipates soft terrain and stiffens the legs before foot strike, largely canceling out whatever cushioning the ground provides. The real injury variable isn't surface, it's pace. Slowing from a 7:40 to a 10:44 mile can cut tibial stress injury risk by over 50%. Variability across surfaces beats avoidance of any one of them.From there, the conversation moves into the "8 Questions" edition and a broader critique of optimization culture. Only about 10 to 15 percent of runners, Alex argues, should even be thinking about supplements, sleep protocols, or anabolic windows. The rest need to nail the basics first. The injury comeback piece brings the most personal material. Alex draws on his own two-year loop of reinjury at Stanford and UNC to argue that healing and readiness are not the same thing. Pain-free is a starting point, not a finish line. Two rules stand above the rest: invest fully in the protection phase, and pass a stimulus twice before progressing it.The episode closes on London 2026 and the fueling science behind the first sub-two. Sawe averaged 115 grams of carbohydrate per hour—a number that would have been considered reckless a decade ago. Alex breaks down the carbolution (dual-source transport, hydrogel delivery, gut training) and asks the question the finish line footage raised: have we eliminated the bonk?Tap into the Alex Ostberg Rundown Recap Special.If you enjoy the podcast, please consider following us on Spotify and Apple Podcasts and giving us a five-star review! S H O W  N O T E S  -The Run Down By The Running Effect (our new newsletter!): https://tinyurl.com/mr36s9rs-Our Website: https://therunningeffect.run  -THE PODCAST ON YOUTUBE: https://www.youtube.com/channel/UClLcLIDAqmJBTHeyWJx_wFQ-My Instagram: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.instagram.com/therunningeffect/?hl=en⁠⁠⁠⁠⁠⁠-Take our podcast survey: https://tinyurl.com/3ua62ffz

Send us Fan MailEvery neonatologist has built a protocol or written a guideline, and most have done it completely alone. In this episode, Ben sits down with Dr. Christina Muffy Sollinger (UC Davis) and Dr. Sarvin Ghavam (CHOP), the co-founders of NeoGuide, a national collaborative dedicated to connecting clinicians around the shared work of clinical guidelines and practice pathways. Born from a single email that broke a listserv and generated over 120 responses overnight, NeoGuide has grown into a structured community offering a seminar series on topics like transfusion medicine and HIE management, and a curriculum series focused on implementation science. Muffy and Sarvin discuss how to build consensus without promoting cookie-cutter medicine, the moral distress of clinical uncertainty, and their vision for a living repository of institutional pathways. Whether you are at a level four academic center or a small rural NICU, you shouldn't have to start from scratch.To learn more, visit NeoGuide.org Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.Enjoy!

The episode highlights a structural transition from software systems that record tasks to platforms that actively participate in business decisions, particularly through agentic AI in procurement. This shift is anchored in the adoption of AI-driven SaaS solutions by mid-market organizations, as seen with Procurify, which reports managing over $100 billion in organizational spend. The mechanism moves beyond basic automation, assigning software agents responsibilities that were traditionally human—such as flagging compliance breaches or routing approvals—directly within operational workflows. According to Chad Gaydos, current deployments of such agentic AI commonly automate tasks like invoice detail verification, policy enforcement, and contract compliance. These developments are most prominent in mid-market environments, where limited staffing—sometimes with no dedicated procurement analysts—drives greater reliance on platforms to perform core operational functions. The focus is not on completely replacing personnel but on supplementing constrained teams and ensuring repeatable enforcement of controls, with organizations leveraging these systems to gain efficiency in both cost and process governance. Additional points discussed reinforce the central shift, such as the distinctive pace of adoption among mid-market firms compared to enterprises. He identifies that smaller organizations often approach these technologies with greater agility and willingness to accept risk, while also displaying heightened dependency on system trust and governance frameworks. The episode also references "frontier firms" co-defined by Microsoft and Procurify, characterized by their forward-leaning adoption of AI and structured standards for technological governance. Variability in governance, auditability, and trust across different organization sizes underlines the operational diversity in adopting agentic platforms. For MSPs and IT leaders, these shifts raise practical concerns around governance design, accountability for software-driven actions, and operational dependency on vendor platforms. Effective risk mitigation requires establishing audit trails, clear standards for automation versus human oversight, and robust compliance controls. Providers supporting mid-market clients should anticipate requests for prescriptive guidance on data and process governance, while also preparing for greater operational reliance on systems that automate, not merely record, business decisions.

Today, we're digging into a topic that's getting a lot more attention lately, how early decisions in cell therapy end up shaping or complicating everything that comes later. Our episode today is Freeze Variability, Not Progress, How to Strengthen Your Cell Therapy Supply Chain from the Start, and we're going to challenge a few long-held beliefs about how starting material should be handled. My guest today is Dominic Clarke, Vice President of Technical Operations for IntegriCell at Cryoport Systems. Dominic has spent years in the trenches building and scaling cell therapy processes from early development through commercialization. So, he's seen where things break and what actually works. I hope you enjoy my conversation with Dominic Clark.01:07    Meet Dominic Clarke and Cryoport Systems06:24   Fresh cells versus frozen cells08:21    Why teams switch to cryopreservation late12:37    The challenge of variability16:47    IntegriCell when you already have a process in place22:17    An argument for cryopreservation based on data25:56   The future of IntegriCell and Cryoport SystemsThis episode is brought to you with the support of Cryoport Systems.Interested in being a sponsor of an episode of our podcast? Discover how you can get involved here! Stay updated by subscribing to our newsletterTo dive deeper into the topic: IntegriCell® CryopreservationCryoport Systems on the state of the ATMP market and the importance of supply chain resilienceCracking the code: Delivering biotherapeutics successfully across EMEA

Welcome to this week's episode of Fast. Feast. Repeat. Intermittent Fasting for Life, with Gin Stephens and Sheri Bullock.To make a submission for the podcast, go to fastfeastrepeat.com/submit.  We are a community-driven podcast, and we look forward to sharing your questions, success stories, non-scale victories, IF tweaks, motivational quotes (and more!) on each episode of the podcast. Resources used in today's episode:Join Gin in the new Fast Feast Repeat app for The Grown-Up Year: 52 Weeks to Listen, Play, and Nourish, as well as a growing collection of intermittent fasting resources. Go to app.fastfeastrepeat.com to join us or go to the App Store and download the Fast Feast Repeat app, available for both iPhone and Android.To get the books, go to https://www.ginstephens.com/get-the-books.html. The second edition of Delay, Don't Deny is now available in ebook, paperback, hardback, and audIo book.  This is the book that you'll want to start with or share with others, as it is a simple introduction to IF.  It's been updated to include the clean fast, a thorough description of ADF and all of your ADF options, and an all new success stories section.  When shopping, make sure to get the second edition, which has a 2024 publication date.  The audiobook for the second edition is also available now!Gin has a new YouTube Channel!  Visit https://www.youtube.com/channel/UC_frGNiTEoJ88rZOwvuG2CA and subscribe today so you never miss an intermittent fasting tip, a support session, or an interview with a past IF Stories guest or expert.Want to learn more about BiOptimizer's Magnesium Breakthrough? Visit www.bioptimizers.com/fastfeastrepeat and use code FFR15 to save 15% off any order. Go to fastfeastrepeat.com to see Gin's and Sheri's favorite things, and to shop with us.  Every purchase you make through links on our website help to support this podcast so we can keep bringing you episodes each week.  Are you ready to take your intermittent fasting lifestyle to the next level? There's nothing better than community to help with that.  In the Delay, Don't Deny community we all embrace the clean fast, and there's just the right support for you as you live your intermittent fasting lifestyle. Connect with both Gin and Sheri in the community, as well as thousands of other intermittent fasters who are there to support you along your journey.  If you're new to intermittent fasting or recommitting to the IF lifestyle, join the 28-Day FAST Start group.  After your fast start, join us for support in The 1st Year group.  Need tips for long term maintenance? We have a place for that!  There are many more useful spaces beyond these, and you can interact in as many as you like.Visit ginstephens.com/community to join us. An annual membership costs just over a dollar a week when you do the math.  If you aren't ready to fully commit for a year, join for a month and you can cancel at any time. If you know you'll want to stay forever, we also have a lifetime membership option available.  IF is free. You don't need to join our community to fast. But if you're looking for support from a community of like-minded IFers, we are here for you at  ginstephens.com/community.

Randall explores the Climategate scandal, present and past, asserting that leaked emails from the University of East Anglia revealed a concerted effort to manipulate data and marginalize skeptical viewpoints. Randall argues that modern climate science has been politicized, moving away from the rigorous transparency required for true scientific replication to favor an anthropogenic warming narrative. By highlighting the work of Hubert Lamb, Randall suggests that the Earth's history is defined by abrupt natural shifts that far exceed the impact of human activity. Randall contends that labeling critics as "deniers" is a rhetorical tactic used to suppress legitimate debate and advance agendas of social control. Ultimately, he claims that focus on carbon dioxide obscures more significant natural drivers of climate change and distracts from the dangers of global conflict.

Guest: Henry Kaminski, MD Myasthenia gravis is an unpredictable condition, with symptoms and treatment responses that can vary widely from one patient to the next. Tune in to hear Dr. Henry Kaminski explain how to navigate this variability and make thoughtful, individualized treatment decisions. Dr. Kaminski is the Meta A. Neumann Professor of the Department of Neurology at The George Washington University School of Medicine and Health Sciences in Washington.

This edWeb podcast is sponsored by Digital Promise.The webinar recording can be accessed here.The middle school years are critical for developing the literacy skills students will use for the rest of their lives. For some learners, the challenge isn't just decoding words but negotiating the intense cognitive demand of managing new vocabulary and constructing meaning. By designing for learner variability—considering a whole-child framework of factors that includes learner background, social and emotional learning, cognition, and literacy—educators can ensure that all learners can unlock their true potential.Join learner variability expert Dr. Stefani Pautz Stephenson and literacy expert Dacia Toll for an insightful edWeb podcast on how to bridge the gap between the high-quality instructional materials that districts have adopted and the diversity of student needs that exist in classrooms.In part one of this three-part series, you learn:How to identify learner variability factors connected to building literacy skills and apply research-backed strategies to help middle school ELA learners thriveStrategies to foster high-level inferencing skills by providing each student with targeted, Socratic, one-on-one, and small-group supportThis edWeb podcast is designed for grades 6-8 educators, instructional coaches, and leaders committed to creating equitable pathways for every unique learner.Part two: Unmasking the Math Mindset: Designing for Learner Variability in Middle SchoolPart three: Leveling Up SEL Through Play and Games: Designing for Learner Variability in Middle SchoolDigital PromiseDigital Promise's mission is to accelerate innovation in education to improve opportunities to learnDisclaimer: This post contains affiliate links. If you make a purchase, I may receive a commission at no extra cost to you.Learn more about viewing live edWeb presentations and on-demand recordings, earning CE certificates, and using accessibility features.

Alpha-gal syndrome is an emerging and often underrecognized allergy triggered by a tick bite that can cause delayed reactions to red meat and mammalian-derived products. In this episode, host Stacy Lauderdale is joined by clinical experts Zack Stacy and Kyna Henrici to unpack the science behind alpha-gal, its implications in healthcare settings, and the operational challenges providers face in managing this complex condition.    Guest Speakers:   Zachary Stacy, Pharm.D., MS, FCCP, BCPS  Clinical Pharmacy Specialist, Surgery  BJC Health   Kyna Henrici, RN  Medical Evidence Director - Cardiovascular  Vizient, Inc.    Host:    Stacy Lauderdale, Pharm.D., BCPS  AVP, Evidence-Based Medicine  Vizient, Inc.    00:05 – Introduction  Podcast introduction and welcome to VerifiedRx  00:14 – What is alpha-gal syndrome  Overview of alpha-gal syndrome  Delayed allergic reactions after eating red meat  Often linked to tick bites  00:48 – Meet the Guests   Zack Stacy, clinical pharmacy specialist  Kyna Henrici, medical evidence director  01:10 – Understanding the Allergy  Alpha-gal is a carbohydrate in nonprimate mammals that can trigger an allergy in humans  Key difference is delayed reaction timing  Symptoms are not always easy to trace   01:32 – How It Develops  Triggered by tick bites  Immune system produces IgE antibodies   Oral exposure to alpha-gal leads to delayed reactions  IV exposure to alpha-gal can cause immediate reactions  02:17 – Prevalence and Diagnosis Challenges  More common in Midwest and southern United States  Likely underdiagnosed  Often mistaken for general food allergies  Allergy may fade over time  03:07 – Risks in Healthcare Settings  Patient safety concerns beyond food  Mammalian components in medications and devices  Examples include heparin and surgical materials  03:44 – Hidden Medication Risks  Inactive ingredients can be animal derived  Examples include glycerin, lactose, amino acids, stearates  Difficult to identify and track  04:42 – Lack of Transparency  No centralized ingredient database  Sourcing can change frequently  Variability across manufacturers and batches  05:33 – Screening in Surgical Settings  Medication review at NDC level  Identification of active and inactive ingredients  May require contacting manufacturers  06:45 – Timing Challenges  Urgent procedures limit investigation time  Manufacturer responses may take days  Alternative medications often needed  07:14 – Identifying At Risk Patients  Many patients are unaware they have alpha-gal syndrome  Screening includes questions about dairy tolerance  Three patient categories used for evaluation  08:32 – Using Dairy as a Screening Tool   Dairy tolerance helps guide risk level  Food exposure typically higher than medication exposure  Determines need for deeper review  09:12 – Managing Emergencies  Focus shifts from avoidance to risk mitigation  Use of team communication and clear documentation  Preparation for unavoidable exposure  10:03 – Prevention and Preparedness  Stock alpha-gal safe medications when possible  Prepare for allergic reactions with standard treatments  10:47 – Team Based Care Approach  Collaboration across care teams is essential  Premedication strategies may be used  Close monitoring for reactions  11:11 – Gaps in Care  Limited visibility into product ingredients  Need for better labeling and transparency  11:33 – Need for Standardization  Call for clearer guidance and clinician education  Desire for centralized resource for medication ingredients  12:24 – Monitoring Challenges  CDC tracking decreased after privatization of testing  Cases likely still increasing  12:53 – Closing Remarks    Links and Resources: Alpha-gal Syndrome | Alpha-gal Syndrome | CDC    Subscribe Today!  Apple Podcasts  Spotify  YouTube  RSS Feed   

Profitibility or reduce variability in profitability. expand markets and uses of agricultural products.

If you work with children who have autism, minimal joint attention, and limited expressive language, this episode challenges what you've been taught and replaces it with something far more useful. This is not a “wait and see” conversation. This is a rethink-everything conversation. Drawing from a powerful systematic review and the lens of dynamic systems theory, this episode breaks down why language development in autism does not follow a predictable path and why that actually changes how we should intervene starting today. You will walk away with a clearer understanding of how language can emerge in unexpected ways, why inconsistency is often a sign of growth, and how to respond in the moment so you do not accidentally shut down emerging communication. This is about seeing the child differently and adjusting your intervention accordingly. What You'll Learn... Why joint attention is not a prerequisite for language The reality that some children develop language without following typical developmental sequences? How children may learn language visually, through patterns, reading, or AAC rather than through listening? Why “inconsistency” in communication is often a sign that a new skill is emerging How dynamic systems theory explains variability in language development? Because the child in front of you is not broken. They are showing you their pathway. You just have to be willing to take it? 3 Clinical Takeaways You Can Use Immediately: There is no single pathway to language Children may not follow a linear progression from babbling to words to sentences. Some may start with scripts, reading, or full phrases. Your job is to identify the pathway and build from it. Variability is not a problem When a child says a word once and then “loses it,” that is not regression. That is emergence. Do not punish inconsistency. Support it. Be dynamic in your response You cannot use a fixed script with a variable system. Adjust moment by moment. Increase support, then fade it. Follow attention, motivation, and engagement in real time. Referenced in This Episode Kissine, M., Saint-Denis, A., & Mottron, L. (2023). Language acquisition can be truly atypical in autism: Beyond joint attention. Neuroscience & Biobehavioral Reviews, 153, 105384. https://doi.org/10.1016/j.neubiorev.2023.105384 Spencer, J. P., Perone, S., & Buss, A. T. (2011). Twenty years and going strong: A dynamic systems revolution in motor and cognitive development. Child Development Perspectives, 5(4), 260–266. https://doi.org/10.1111/j.1750-8606.2011.00194.x Your Next Step If this episode is hitting something for you, if you're realizing that your therapy needs to shift from linear to dynamic, then you need tools that actually match that approach. Because insight without application does not change outcomes. Inside the SIS Membership, you get weekly, ready-to-use, literacy-based movement activities that are built for exactly this kind of work. You are not guessing what to do next You are not piecing together random strategies You are walking into your sessions with a clear, research-informed plan that supports real language growth This is where theory meets practice in a way that actually works.

BUFFALO, NY — April 2, 2026 — A new #research paper was #published in Volume 18 of Aging-US on March 24, 2026, titled “Age-specific relationship between the modulation of brain dynamics in response to task demands and bimanual performance.” Led by first author Sara Magalhães Ferreira from Hasselt University, with corresponding author Koen Cuypers from Hasselt University and KU Leuven, the study examined how age affects BOLD variability and its modulation with task demands during a bimanual task. The authors used fMRI in 22 younger and 23 older healthy adults who performed three increasingly complex task conditions. The authors found that older adults showed higher BOLD variability in cerebellar lobule VIIIb and greater modulation across task conditions in sensorimotor and cerebellar regions. Modulation of BOLD variability predicted performance in an age- and region-dependent manner: in younger adults, reduced modulation in sensorimotor and visuospatial areas correlated with better performance, whereas in older adults, increased modulation in the inferior and superior parietal lobules was linked to higher performance. Across groups, better outcomes were associated with greater modulation in the middle occipital gyrus but lower modulation in cerebellar Crus I. “In sum, this study highlights the potential role of BOLD variability modulation in shaping bimanual performance during aging.” The authors note that, while the age-related differences in BOLD dynamics were clear, they did not find robust evidence supporting a brain-behavior relationship in bimanual performance, which limits how directly the neural findings can be interpreted behaviorally. They recommend future work using multimodal imaging, longitudinal designs, and studies that examine both cognitive and motor domains within the same participants to determine whether variability modulation reflects aging, experience, intervention, or broader cross-functional signatures of aging. DOI - https://doi.org/10.18632/aging.206363 Corresponding author - Koen Cuypers - koen.cuypers@uhasselt.be Abstract video - https://www.youtube.com/watch?v=3TbcGFCZV9s Sign up for free Altmetric alerts about this article - https://aging.altmetric.com/details/email_updates?id=10.18632%2Faging.206363 Subscribe for free publication alerts from Aging - https://www.aging-us.com/subscribe-to-toc-alerts Keywords - aging, bimanual coordination, Bimanual Tracking Task, BOLD variability, task modulation To learn more about the journal, please visit https://www.Aging-US.com​​ and connect with us on social media at: Bluesky - https://bsky.app/profile/aging-us.bsky.social ResearchGate - https://www.researchgate.net/journal/Aging-1945-4589 X - https://twitter.com/AgingJrnl Facebook - https://www.facebook.com/AgingUS/ Instagram - https://www.instagram.com/agingjrnl/ LinkedIn - https://www.linkedin.com/company/aging/ Reddit - https://www.reddit.com/user/AgingUS/ Pinterest - https://www.pinterest.com/AgingUS/ YouTube - https://www.youtube.com/@Aging-US Spotify - https://open.spotify.com/show/1X4HQQgegjReaf6Mozn6Mc MEDIA@IMPACTJOURNALS.COM

Manufacturing organizations face a wide range of interconnected risks—from supply chain disruptions and inventory shortages to customer concentration and pricing volatility. Yet many still rely on traditional "what if" scenarios that fail to capture how these risks interact and compound, limiting their ability to anticipate performance shortfalls. Join Glen Justis, CEO of Acclaim Strategies, LLC, to see how leading manufacturers use Monte Carlo methods to analyze the interaction of manufacturing risks and support the development of more effective risk mitigation strategies. In this session, you'll learn: Why traditional "what if" analysis falls short for manufacturing risk decisions How deeper insight into risk variability supports better, more resilient manufacturing decisions Strategies to model supply chain and inventory risk, evaluate customer concentration, and support pricing optimization under uncertainty Presenter: Glen Justis CEO, Acclaim Strategies, LLC Brought to you by: LUMIVERO Visit https://advancedmanufacturing.org/webinars for more webinars and an interactive experience with visuals.  

In today's episode, we spoke with Ticiana Leal, MD, about variability in community practice and evolving treatment strategies for patients with small cell lung cancer (SCLC). Dr Leal is a professor and director of the Thoracic Medical Oncology Program in the Department of Hematology and Medical Oncology at Emory University School of Medicine, as well as the medical director of the Clinical Trials Office at Winship Cancer Institute in Atlanta, Georgia.In our exclusive interview, Dr Leal began by discussing how SCLC management can differ widely across community settings according to how patients present. Leal emphasized the importance of quickly confirming a patient's diagnosis and initiating treatment to avoid missing the critical window where chemotherapy could provide meaningful clinical benefit. However, Leal noted that the field still lacks predictive biomarkers to guide treatment selection. Accordingly, current strategies, including chemoimmunotherapy, maintenance approaches, and second-line options like tarlatamab-dlle (Imdelltra) and lurbinectedin (Zepzelca) are largely chosen based on clinical factors such as disease burden, comorbidities, and patient preferences.The conversation then shifted to the challenge of treating patients who may not meet traditional clinical trial eligibility criteria due to poor performance status, comorbidities, or social vulnerabilities. Leal stated that a multidisciplinary approach, including collaboration with supportive care teams, is essential to optimize outcomes for these patients. She noted that potential solutions to restrictive trial eligibility criteria may include decentralizing trials, improving collaboration between academic and community centers, and providing additional patient support such as transportation and care navigation services.Looking ahead, Leal emphasized the need for community practices to prepare for emerging therapies, including antibody-drug conjugates and novel immunotherapy approaches. Successfully integrating these treatments into everyday practice will require education, infrastructure development, and multidisciplinary collaboration, Leal imparted.

In this episode, oil scientist and adjunct professor Dr. Kurt Spokas talks about how biochar quality can vary vastly through their feedstock and charring methods.   Subscribe for more content on sustainable farming, market farming tips, and business insights!   Get market farming tools, seeds, and supplies at Modern Grower. Follow Modern Grower:  Instagram  Instagram Listen to other podcasts on the Modern Grower Podcast Network:  Carrot Cashflow  Farm Small Farm Smart  Farm Small Farm Smart Daily  The Growing Microgreens Podcast  The Urban Farmer Podcast  The Rookie Farmer Podcast  In Search of Soil Podcast Check out Diego's books:  Sell Everything You Grow on Amazon   Ready Farmer One on Amazon **** Modern Grower and Diego Footer participate in the Amazon Services LLC. Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com.

In this episode, oil scientist and adjunct professor Dr. Kurt Spokas talks about how biochar quality can vary vastly through their feedstock and charring methods.   Subscribe for more content on sustainable farming, market farming tips, and business insights!   Get market farming tools, seeds, and supplies at Modern Grower. Follow Modern Grower:  Instagram  Instagram Listen to other podcasts on the Modern Grower Podcast Network:  Carrot Cashflow  Farm Small Farm Smart  Farm Small Farm Smart Daily  The Growing Microgreens Podcast  The Urban Farmer Podcast  The Rookie Farmer Podcast  In Search of Soil Podcast Check out Diego's books:  Sell Everything You Grow on Amazon   Ready Farmer One on Amazon **** Modern Grower and Diego Footer participate in the Amazon Services LLC. Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com.

In this episode of Longevity by Design, host Dr. Gil Blander sits down with Dr. Uri Alon, Professor at Weizmann Institute of Science. They explore a systems view of aging that treats longevity as a solvable model, not a grab bag of disconnected theories.Uri explains aging with a simple story: houses make garbage, trucks remove it, and the village has a threshold for how much damage it can handle. In the body, “garbage” can include damaged and senescent cells, “trucks” can include immune cleanup, and “houses” can include long-lived cells and stem cells that drift over time. The model links this balance to death, disease, and steady decline, and it helps predict which interventions actually change it.They also revisit the role of genes. Uri argues that lifespan looks closer to 50% heritable today after correcting for early, non-aging deaths in older datasets. The rest comes from the environment and biological noise, which regular sleep may help reduce.Guest-at-a-Glance

What happens when a data-obsessed mind that could have been optimizing portfolios decides to optimize powder days instead? This episode features meteorologist and OpenSnow founder Joel Gratz in a deep dive on snow, skiing, and the science of weather forecasting, told through the lens of someone who treats every incoming storm like a market opportunity.Joel shares how a childhood obsession with snow days in Pennsylvania led to studying meteorology, moving to Boulder, and eventually creating OpenSnow, essentially a Bloomberg Terminal for skiers chasing powder. He explains the real science behind why some mountains get more snow than others, how local wind and terrain effects work, and why long-range seasonal forecasts are about as reliable as a sell-side price target for planning your ski trips.Joel and Jeff also explore the realities of climate change and snowpack (warmer temperatures vs. largely unchanged long-term precipitation), how subscription passes like Epic and Ikon affect crowd dynamics, think of it as indexing degrading your alpha, and why niche, bootstrapped businesses like OpenSnow can thrive without trying to own all of weather. They get into powder quality, snow-to-liquid ratios, and why Utah sits in a global sweet spot for both depth and fluff, the true asymmetric bet in skiing. Plus: what makes Japan, British Columbia, and Colorado so special for different kinds of ski experiences. The conversation is equal parts nerdy meteorology, entrepreneurial journey, and pure powder stoke.… SEND IT!Chapters:00:00-01:52= Intro01:18-11:06= From Snow-Obsessed Kid to OpenSnow Founder: Joel Gratz's Origin Story11:07-24:18= How OpenSnow Helps You Time Powder (and Why 6‑Month Forecasts Don't Work)24:19-39:28=Bad Snow Year or Climate Change? Joel Gratz on Drought, Variability, and the Future of Snow39:29-49:26= Epic, Ikon, and the Powder Problem: Crowds, Passes, and Chasing Better Ski Days49:27-01:00:25= Utah, Japan, and the Quest for Perfect Powder: Joel Gratz on Global Snow Quality01:00:26-01:13:24= Dream Lines and Bucket-List Mountains: Joel Gratz on His Favorite Ski Destinations01:13:25-01:17:46= Ski Movies, Nostalgia, and Parting Powder WisdomFrom the Episode:Jeff Masters The Derivative Podcast Episode: Super Storms, Mathematical Modeling, and Hurricane Hunting with Dr. Jeff MastersMeb Faber's Top Ski resorts - JapanCitrini Research AI piece: When Skynet Writes a Substack: The AI Doom Piece That Moved MarketsDon't forget to subscribe to⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠The Derivative⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠, follow us on Twitter at⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@rcmAlts⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ and⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠sign-up for our blog digest⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.Disclaimer: This podcast is provided for informational purposes only and should not be relied upon as legal, business, or tax advice. All opinions expressed by podcast participants are solely their own opinions and do not necessarily reflect the opinions of RCM Alternatives, their affiliates, or companies featured. Due to industry regulations, participants on this podcast are instructed not to make specific trade recommendations, nor reference past or potential profits. And listeners are reminded that managed futures, commodity trading, and other alternative investments are complex and carry a risk of substantial losses. As such, they are not suitable for all investors. For more information, visit⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠www.rcmalternatives.com/disclaimer⁠⁠⁠⁠

On this episode we were joined by special guest physical therapist Michael Tankovich! Torque regulation is influenced by the nature of the isometric contraction Bauer P, Gomes JS, Oliveira J, et al. Sensors. 2023;23(2):726. doi:10.3390/s23020726 The movement variability paper Chris mentioned: https://link.springer.com/article/10.1186/s40798-022-00473-4 Due to copyright laws, unless the article is open source we cannot legally post the PDF on the website for the world to download at will. Brought to you by our sponsors at: CSMi – https://www.humacnorm.com/ptinquest VALD MoveHealth - https://movehealth.me/ Learn more about/purchase our courses: The Science PT | Dungeons & Dynamometers Support us on the Patreons! Music for PT Inquest: "The Science of Selling Yourself Short" by Less Than Jake Used by Permission Other Music by Kevin MacLeod – incompetech.com: MidRoll Promo – Mining by Moonlight Koal Challenge – Sam Roux  

Full article: Quantitative CT Measurements of Interstitial Lung Disease: Same-Day Variability Between Two Vendors—A Prospective Study Longitudinal monitoring of interstitial lung disease (ILD) requires insight into the variability of quantitative ILD measurements. Dora Chen, MD, discusses the article by Ahn et al. reporting results of a prospective study in which patients with ILD underwent same-day chest CT examinations using scanners from different vendors.  

PRVIEW FOR LATER: Colleague Bob Zimmerman explains the discovery of two exoplanets colliding near a sun-like star. Astronomers observed star variability for 200 days, concluding that debris came from a massive planetary impact. (6)1956

Thomas is a young coach with a bright future, a disciple  of Thomas Iisalo, and carving out his own path and philosophies that are creating ripples throughout the euroleague and the world. Tyler and Coleman sit down with Thomas Pennellier to dive deep into the art and science of coaching, skill acquisition, and player development. Thomas shares his journey from strength and conditioning into skill development, unpacking how his exposure to ecological dynamics and constraints-led approaches reshaped the way he views practice design. He challenges traditional drill-based models and emphasizes representative learning environments, variability, and perception-action coupling as the foundation for developing adaptable, game-ready players.Throughout the conversation, we explore how coaches can better balance structure with freedom, design practices that truly transfer to competition, and avoid the trap of over-isolated skill work. Thomas also discusses working within team settings, navigating organizational constraints, and how to build athletes who can self-organize under pressure. This episode is packed with practical insights for coaches who want to evolve beyond scripted drills and build smarter, more adaptable players.00:00 Introduction and Thomas' coaching background 06:12 Transition from strength & conditioning to skill acquisition 12:08 Discovering ecological dynamics and constraints-led coaching 18:47 Designing representative practice environments 24:35 Variability vs. repetition in player development 30:22 The limitations of isolated, drill-based training 36:10 Transfer: ensuring practice shows up in games 42:18 Coaching in team settings and managing constraints 48:26 Balancing structure and freedom in practice 54:40 Common mistakes in modern player development 01:00:15 Practical ways to implement these concepts immediatelyBAM Coaches Platform: https://byanymeanscoaches.com/BAM Blueprint Book: https://byanymeanscoaches.com/blueprint-bookIf you enjoyed this episode, make sure to subscribe, leave a review, and share it with another coach who's committed to building smarter, more adaptable players. We'll see you in the next one.

In this Huberman Lab Essentials episode, my guest is Jeff Cavaliere, MSPT, CSCS, a physical therapist, strength coach and the founder of ATHLEAN-X, an online training platform. We explain the foundations of an effective training program, including how to structure your weekly workouts and recovery to match your goals and schedule. We also discuss effective warm-ups and stretching, strategies to reduce injury risk and practical nutrition principles without strict calorie counting. Jeff's science-based approach offers clear, actionable guidance for anyone looking to improve fitness, physique and overall health. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman BetterHelp: https://betterhelp.com/huberman Helix: https://helixsleep.com/huberman David: https://davidprotein.com/huberman Timestamps (00:00:00) Jeff Cavaliere (00:00:20) Beginner Whole Body Training Program, Warm-Ups (00:02:18) Splits, Time Efficiency, Recovery; Bro Splits (00:05:07) Sponsor: BetterHelp (00:06:18) Cardiovascular & Resistance Training, Timing & Frequency; Blending Strategies (00:09:24) Cramp Test & Resistance Training, "Cavaliere Test", Muscularity (00:11:55) Recovery, Soreness & Variability; Tool: Grip Strength Test (00:14:48) Sponsor: Helix Sleep (00:16:22) Active vs Passive Stretching, Recovery (00:18:46) Recovery, Heal "Shorter" & Muscle; Dynamic Stretching (00:20:55) Upright Row, Shoulder, Posture, Tool: High Pull; Strengthening Hips (00:26:10) Sponsor: AG1 (00:27:01) Tool: Proper Bar Grip, Elbow Pain (00:31:26) Tool: Training Journal & Goals (00:32:03) Nutrition; Tool: Plate Method (00:35:28) Sponsor: David (00:36:47) Post-Training Meal, Protein; Pre-Workout Supplements (00:39:04) Acknowledgements Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices

In this episode of the Neurocritical Care Society Podcast Hot Topics series, host Richard Choi, DO, FNCS, speaks with Wendy Ziai, MD, MPH, professor of neurology and critical care medicine at Johns Hopkins University, about the article The Association Between Hourly Systolic Blood Pressure Variability and Outcomes in Patients With Intracerebral Hemorrhage Is Time-Dependent: A Post Hoc Analysis of the ATACH-2 Trial, recently published in Neurocritical Care. Their discussion explores why blood pressure variability — not just absolute blood pressure targets — may play a critical role in outcomes following acute intracerebral hemorrhage. Dr. Ziai reviews key findings from ATACH-2 and INTERACT trials, the physiologic mechanisms that may link variability to hematoma expansion and neurologic deterioration and why the timing of variability within the first 8 to 12 hours appears especially important. They also examine the unresolved question of causation versus association, implications for antihypertensive management in the ICU and how emerging trials focused on variability may shape future practice. The views expressed on the NCS Podcast are solely those of the hosts and guests and do not necessarily reflect the opinions or official positions of the Neurocritical Care Society.

About the Guest(s): Dr. Kristin Hieshetter is the host of Functional Health Radio, an established healthcare professional with expertise in functional medicine, chiropractic care, and neuroinflammation. With a rich background in educating medical, chiropractic, and dental professionals, Dr. Kristin is dedicated to translating complex medical research into practical knowledge for both her peers and the general public. She regularly integrates insights from reputable medical journals into her work and travels to share her knowledge at various continuing education events for healthcare providers. Episode Summary: In this engaging episode of Functional Health Radio, Dr. Kristin Hieshetter delves into the implications of COVID-19 as a brain disease, discussing its impact on long-term neurological health and offering insights into potential therapeutic strategies. Highlighting the struggles faced by the 225 million individuals worldwide known as "Covid long haulers," Dr. Kristin shares her expertise on the often debilitating neurological symptoms that persist in many patients well after recovery from the initial infection. Throughout the episode, Dr. Kristin explores the science behind COVID-19's effects on the brain, emphasizing the structural impact of the virus's spike proteins and their lingering presence. By referencing several studies, including those published in top-tier journals such as Molecular Neurobiology and Nature Medicine, she discusses the immune-mediated pathways that lead to neuroinflammation, cognitive deficits, and reduced gray matter in COVID-19 patients. She sheds light on the necessity for personalized protocols when treating long-haul symptoms, combined with the use of low-level lasers, supplements, and lifestyle changes to promote healing and brain health. Key Takeaways: COVID-19 can have long-term neurological effects, leading to symptoms such as brain fog, memory loss, and anxiety. Spike proteins from the virus remain in the body, contributing to neuroinflammation and facilitating long-term cognitive issues. Integral therapeutic approaches include tailored supplementation, regular exercise, low-level laser therapy, and controlled doses of methylene blue. Variability in patient responses necessitates highly individualized treatment plans to manage and potentially reverse symptoms. Maintaining brain health requires attention to exercise, nutrition, and supplementation to combat the inflammatory effects of the virus. Notable Quotes: "Both long Covid and COVID vaccine can sometimes create things like brain fog, neuroinflammation, and long term sequelae." "We have more abnormal than normal brains in the world." "The COVID spike proteins, they hang out at the base of the skull, throughout the skull, in a system called the duromeningeal system." "COVID long haulers have way too much inflammation. Low-level laser can help you with that." "For every nerve that goes from the brain to the stomach, nine go back up." Resources: PubMed: Molecular Neurobiology, July 2021 Journal Article: Cell Host and Microbe, Volume 32, 2024 Dr. Greg Fors - BioSpec Nutritionals: Mito Detox 3 Nature Medicine, Volume 31, 2025 Listeners are encouraged to dive into this informative episode to understand fully the complex nature of COVID-19 as a brain disease and its long-term implications on health. Join Dr. Kristin as she prepares to address these pertinent challenges faced by many today and provides tools for navigating them. Stay tuned for more episodes of Functional Health Radio for continued learning and insight.

Functional Neurological Disorder (FND) is often misunderstood... but it's real, common, AND treatable. In this episode of Talk Dizzy To Me, vestibular physical therapists Dr. Abbie Ross, PT, NCS and Dr. Carly Lochala, PT, NCS sit down with Dr. Julie Hershberg, PT, NCS to explain what FND is, why it's been minimized in healthcare, and how it overlaps with dizziness, migraine, dysautonomia/POTS, hypermobility/EDS, and vestibular disorders.They break down brain networks like the default mode network and salience network, discuss common clinical clues (variability, attention-related shifts), and explain how treatment often starts with nervous system regulation, trust-building, and whole-person care—not just exercises.If you've been told your symptoms are “all in your head,” this episode is for you.Guest: Dr. Julie Hershberg / Reactive PT Instagram: @reactiveptResources: FND resources hub, reactivept.com/FNDresourcesHosted by:

Hemang Yadav, MBBS, joins CHEST® Journal Podcast Moderator Alice Gallo De Moraes, MD, FCCP, to discuss his research into the magnitude and determinants of diffusing capacity for carbon monoxide intersession variability in routine clinical practice and evidence-based thresholds that can guide interpretation of serial measurements. DOI: 10.1016/j.chest.2025.09.006 Disclaimer: The purpose of this activity is to expand the reach of CHEST content through awareness, critique, and discussion. All articles have undergone peer review for methodologic rigor and audience relevance. Any views asserted are those of the speakers and are not endorsed by CHEST. Listeners should be aware that speakers' opinions may vary and are advised to read the full corresponding journal article(s) for complete context. This content should not be used as a basis for medical advice or treatment, nor should it substitute the judgment used by clinicians in the practice of evidence-based medicine.  

This episode previews a small workshop in Santa Fe where Todd Conklin, Ann Lyren, and guest ReDonda Vaught will explore a tragic patient safety case. They frame accidents as the unexpected combination of normal performance variability and discuss how to learn from such incidents. Listeners will hear about the meeting goals (March 31–April 1), opportunities to chart the event, and practical tactics for organizations to identify and respond to accumulating risks, with cross-industry lessons and a focus on improving safety culture.

In this conversation, Jeff Sarris and Jill Harris discuss the safety of quinoa for individuals with kidney stones, referencing recent studies and the importance of portion control. They emphasize the variability in oxalate content in foods and provide practical tips for managing dietary intake to prevent kidney stones. The discussion also highlights resources available for individuals seeking to understand their dietary needs better.TakeawaysQuinoa has been a topic of debate regarding its safety for kidney stone patients.Harvard's recent study on quinoa has clarified its oxalate content.Portion control is crucial; half a cup of quinoa is recommended.Variability in food composition affects oxalate levels.Dietary changes can significantly impact kidney stone formation.It's important to meet calcium needs daily, even with higher oxalate foods.Meal plans and recipes are available to help manage oxalate intake.The oxalate searchable list is a valuable tool for dietary management.Consultations with experts can provide personalized dietary guidance.Understanding food portions can alleviate anxiety about eating higher oxalate foods.00:00 Understanding Quinoa and Kidney Stones06:15 Practical Tips for Managing Oxalate Intake——HAVE A QUESTION? _Leave us a voicemail at (773) 789-8764.KIDNEY STONE DIET® APPROVED PRODUCTSProtein Powders, Snacks, and moreWORK WITH JILL _Start HereKidney Stone Diet® All-Access PassKidney Stone Diet® CourseKidney Stone Diet® Meal PlansKidney Stone Diet® BooksPrivate Consultation with JillOne-on-One Deep Dive24-Hour Urine AnalysisSUPPORT THE SHOW _Join the PatreonRate Kidney Stone Diet on Apple Podcasts or Spotify——WHO IS JILL HARRIS? _Since 1998, Jill Harris has been the #1 kidney stone prevention nurse helping patients reduce their kidney stone risk. Drawing from her work with world-renowned University of Chicago nephrologist, Dr. Fred Coe, and the thousands of patients she's worked with directly, she created the Kidney Stone Diet®. With a simple, self-guided online video course, meal plans, ebooks, group coaching, and private consultations, Kidney Stone Diet® is Jill's effort to help as many patients as possible prevent kidney stones for good.

On parle sans cesse de ce que l'on mange, mais presque jamais des rythmes dans lesquels on nous oblige à vivre. Et ça change tout.Bienvenue dans cette mini-série du podcast Dans la poire ! consacrée aux liens profonds entre capitalisme, organisation du temps et alimentation.5 épisodes courts pour explorer des mécanismes invisibles qui influencent nos choix alimentaires au quotidien, bien au-delà du stress, du manque de temps ou de la simple “volonté individuelle”.Cette série est complémentaire à ma newsletter Sous pression : le coût invisible du capitalisme sur notre rapport à la nourriture, disponible en accès libre sur Substack. Dans ce premier épisode, je vous parle d'un phénomène encore peu connu mais extrêmement répandu : le jet lag social.Un décalage permanent entre notre horloge biologique interne, celle qui régule le sommeil, la faim, la digestion, et les horaires imposés par l'organisation sociale du travail : horaires décalés, écrans tardifs, nuits écourtées, week-ends de récupération, rythmes fragmentés.Sans prendre l'avion, beaucoup d'entre nous vivent ainsi dans un état de désynchronisation chronique.Je vous explique comment ce jet lag social perturbe la faim, la satiété et l'énergie, pourquoi il favorise les envies de sucre et de gras, et en quoi il touche particulièrement les soignant·es, les travailleur·ses en horaires atypiques, les parents solo, les métiers de service, de nuit ou en 3x8… autrement dit : une large partie de la population.Je vous montre que ce n'est pas un problème individuel, mais bien un effet secondaire de notre organisation collective du temps, profondément liée au modèle capitaliste.Enfin, je vous propose des pistes de réflexion accessibles pour cesser de culpabiliser face à un corps qui tente simplement de s'adapter.Si votre faim vous semble confuse, si vos envies alimentaires surgissent sans logique apparente, si votre énergie fluctue… ce n'est peut-être pas que votre corps “fonctionne mal”, mais qu'il évolue dans un rythme devenu hostile.

Episode 333 hosts Mike Clague (Nurse Injector from Melbourne, Australia) In 'The Tox Talks' episodes we feature expert injectors who have significant experience in using botulinum toxins. These episodes explore our guests experiences using particular brands, the evolution of their injecting techniques and we get special insights into the subtle nuances of getting the best out of toxins. In chapter 11 we talk about Relfydess, a new Botulinum Toxin A manufactured by Galderma. We first re-introduce Mike (previously on episode 276) and his clinical background. We then cover his involvement in the pre-launch trials using Relfydess and his clinical experience with the product. We covers the efficacy and onset of Relfydess compared to other toxins, its performance in various facial areas, and discuss practical tips for injectors.  00:00 Introduction and Podcast Overview 00:40 Welcome to Chapter 11: The Tox Talks 00:53 Introducing Mike Clague and Relfydess Toxin 01:28 Mike's Background and Experience 03:31 Discussion on Toxin Efficacy and Longevity 06:20 Practical Insights and Injection Techniques 12:53 Patient Experiences and Feedback 24:10 Manufacturing and Purity of Toxins 27:09 Discussion on Antibody Levels 27:44 Patient Reactions to Treatment Onset 28:24 Dosage and Treatment Techniques 31:00 Commercial Implications of Treatment Frequency 32:34 Longevity and Variability of Treatment Effects 42:57 Training and Mentorship in Medical Practice 46:53 Regulations and Compliance in Medical Advertising 50:07 Final Thoughts and Farewell ALL IA LINKS & CONTACT INFORMATION

Today's guest is Hayden Mitchell, Ph.D.  Hayden is a sports performance coach, educator, and researcher specializing in movement ecology and pedagogy, helping coaches design environments that support learning, resilience, self-actualization, and sustainable athletic performance through play and exploration. There is a great deal of conversation in sports performance around methods, including exercises, drills, systems, and models, but far less attention is given to coaching itself. Coaching methodology quietly shapes how athletes experience training, how they relate to challenge and failure, and ultimately how fully they are able to express themselves in performance. On the show today, Hayden speaks about exploring how coaching and physical education shape not just performance, but the whole human being. Hayden shares his path through sport, teaching, and doctoral work, including how life experiences changed his approach to leadership, control, and play. Together they discuss movement ecology, value orientations in coaching, such as mastery, learning process, self-actualization, social responsibility, and ecological integration, and why environment often matters as much as programming. The conversation highlights rhythm, joy, and exploration, along with practical ways coaches can use restraint, better questions, and playful constraints to help athletes own their development. Today's episode is brought to you by Hammer Strength. Use the code “justfly20” for 20% off any Lila Exogen wearable resistance training, including the popular Exogen Calf Sleeves. For this offer, head to Lilateam.com Use code “justfly10” for 10% off the Vert Trainer View more podcast episodes at the podcast homepage. (https://www.just-fly-sports.com/podcast-home/) Timestamps 0:00 – Hayden's coaching background 6:42 – Learning through experimentation 13:55 – Movement quality versus output 21:18 – Constraints based coaching 30:07 – Strength that transfers 39:50 – Variability and resilience 48:26 – Developing youth athletes 57:41 – Decision-making under fatigue 1:06:10 – Simplifying training programs 1:14:22 – Long term coaching philosophy Actionable Takeaways 6:42 – Learning through experimentation builds better coaches and athletes. Early coaching growth often comes from trying ideas, observing outcomes, and refining approaches. Allow room for trial and error in training rather than locking into rigid systems too early. Encourage athletes to feel and explore movement solutions instead of chasing perfect reps. Reflection after sessions helps clarify what actually transferred versus what just looked good. 13:55 – Movement quality creates the foundation for sustainable performance. Chasing outputs too early can hide inefficient movement strategies. Build positions, shapes, and rhythm before emphasizing max speed or max load. Use submaximal work to groove coordination and reduce compensation patterns. Improved movement quality often raises outputs without directly training them. 21:18 – Constraints guide learning better than constant verbal correction. Design drills that naturally guide athletes toward desired solutions. Reduce cue overload by letting the task do the teaching. Constraints promote adaptability instead of dependency on coaching feedback. This approach scales well in team settings with limited coaching bandwidth. 30:07 – Strength training should support movement, not replace it. Choose lifts that reinforce postures and force directions seen in sport. Avoid chasing strength numbers that disrupt rhythm or coordination. Use strength work to enhance confidence and robustness, not fatigue accumulation. Strong athletes still need to move well under dynamic conditions. 39:50 – Variability is a key driver of resilience. Expose athletes to multiple movement patterns and speeds. Avoid over standardizing drills to the point of robotic execution. Small variations build adaptability without sacrificing intent. Resilient athletes tolerate change better during competition. 48:26 – Youth athletes need exposure, not specialization. Prioritize broad skill development over early performance metrics. Multiple sports and movement environments improve long term ceilings. Avoid labeling young athletes too early based on temporary traits. Early diversity reduces burnout and overuse issues. 57:41 – Decision-making matters when athletes are tired. Fatigue reveals movement habits and decision quality. Train cognition alongside physical outputs when appropriate. Simple competitive games expose real world decision challenges. Performance under fatigue reflects true readiness. 1:06:10 – Simple programs executed well outperform complex plans done poorly. Clarity improves athlete buy in and consistency. Fewer exercises done with intent beat bloated sessions. Complexity should serve adaptation, not ego. Great programs are easy to repeat and sustain. 1:14:22 – Long term development requires patience and perspective. Short term gains should not compromise future potential. Progress is rarely linear, especially in young athletes. Coaching success is measured in years, not weeks. Build athletes you would want to train again in five years. Quotes from Hayden “Good movement solves a lot of problems before strength ever enters the conversation.” “When you design the environment well, you do not need to talk nearly as much.” “Outputs are easy to measure, but they are not always the most important thing.” “Variability is not chaos. It is preparation.” “Athletes who only know one solution struggle when conditions change.” “Young athletes do not need more specialization, they need more experiences.” “Strength should support expression, not restrict it.” “Simple does not mean easy. It means intentional.” “Fatigue exposes habits, not flaws.” “The goal is not just better athletes, but athletes who last.” About Hayden Mitchell Hayden Mitchell, PhD is a sports performance coach, educator, and researcher whose work sits at the intersection of movement ecology, pedagogy, and human development. He has coached and taught across a wide range of settings, from youth and collegiate sport to military, adaptive populations, and general fitness, working with ages 4 to 90. Hayden holds a doctorate in Human Performance and Sport Pedagogy and focuses on how environment, values, and teaching behaviors shape learning, resilience, and performance. His work emphasizes play, rhythm, and self-actualization, helping coaches and athletes move beyond rigid systems toward practices that develop both performance capacity and the whole human being.

Today's guest is Dr. Jarod Burton. Jarod is a chiropractor and sports performance coach focused on neurology-driven movement. He blends manual therapy, strength modailities, and nervous system training to unlock better mechanics and athletic output. His work centers on identifying and clearing the neural limits that hold athletes back. In training, there are many layers to human performance and athletic outputs. One critical layer is the power transmission of the nervous system, and how to unlock this ability in all athletes. Many athletes naturally have a more adept system, while others may need more bridges to reach their highest levels of performance. In this episode, Jarod speaks on how his approach has evolved since entering clinical practice. He shares how he uses flywheel training to teach rhythm, “the dance” of force, and powerful catches rather than just concentric effort. He and Joel dig into spinal mobility, ribcage expansion, and even breakdance-style spinal waves as underrated keys to athletic freedom. Jarod then simplifies neurology for coaches, explaining how posture reveals brain-side imbalances and how targeted “fast stretch” work, loud/sticky altitude drops, and intelligently high training volumes can rebalance the system and unlock performance. Today's episode is brought to you by Hammer Strength. Use the code “justfly20” for 20% off any Lila Exogen wearable resistance training, including the popular Exogen Calf Sleeves. For this offer, head to Lilateam.com Use code “justfly10” for 10% off the Vert Trainer View more podcast episodes at the podcast homepage. (https://www.just-fly-sports.com/podcast-home/) Timestamps 0:00 - Jarod's background and early coaching lens6:55 - Internal vs external focus and simple cues13:40 - What good movement feels like20:10 - Speed shapes and improving posture29:18 - Blending strength with elastic qualities41:02 - Breathing mechanics and better movement options52:37 - Pelvis function and creating better positions1:00:15 - Skill acquisition and training that sticks1:11:48 - Programming principles and individual needs1:19:40 - Coaching philosophy and athlete communication Actionable Takeaways 0:00 – Jarod's background, influences, and early coaching lens Jarod draws heavily on mentors in track and field, particularly their ability to teach posture, projection, and simple shapes. He notes that he used to overcoach mechanics and learned that athletes need experiences, not micromanagement. Emphasize principles over preferences. As Jarod says, “If I can teach the principles, the application can change.” 6:55 – Internal versus external focus and simple cues that work Jarod prefers cues that help athletes feel positions instead of thinking about them. He explains that internal cues can work when used to create awareness, but they cannot dominate the session. Use cues that point the athlete toward an outcome. For example, he prefers “push the ground away” instead of detailed joint instructions. 13:40 – What good movement feels like and the problem with forcing technique Jarod warns that coaches often chase “pretty” movement at the cost of effective movement. Technique should emerge from intention, not the other way around. He encourages coaches to give athletes tasks that naturally produce the shapes they want. If an athlete is struggling, simplify the environment rather than stack more verbal instructions. 20:10 – Speed development, posture, and improving shapes without overcoaching Jarod explains that acceleration improves when athletes learn to project rather than lift. Upright running quality comes from rhythm and relaxation, not from forcing tall mechanics. He recommends using contrast tasks to improve posture, such as wall drills combined with short accelerations. Let the environment teach the athlete and save verbal coaching for key errors only. 29:18 – Blending strength training with elastic qualities Jarod sees weight room work as support, not the driver, of speed and skill. He focuses on the elastic properties of tendons and connective tissue for speed athletes. He notes that heavy lifting can coexist with stiffness and elasticity if programmed strategically rather than constantly chased. Use low amplitude hops, bounds, and rhythm-based plyos to balance the traditional strength program. 41:02 – Breathing, ribcage mechanics, and natural movement options Jarod uses breathing work to help athletes find positions that allow better rotation and force transfer. He explains that tight ribcages limit athletic expression, not just breathing capacity. Many athletes struggle with rotation due to rigid breathing patterns, not lack of strength. Use breathing resets before high-speed work to create better movement “access.” 52:37 – Understanding the athletic pelvis and creating better positions Jarod emphasizes that pelvic orientation shapes nearly every aspect of movement. He encourages developing a pelvis that can both yield and create force, instead of being locked in extension or tucked under. Simple low-level movements like hip shifts, step-ups, and gait-primer patterns can transform sprint positions. Train the pelvis in motion, not just through isolated exercises. 1:00:15 – Skill acquisition, variability, and choosing training that sticks Jarod believes athletes need movement options and adaptability, not one perfect model. Variability builds resilience and skill transfer. Too much rigidity in training creates athletes who cannot adapt to chaotic sport environments. Coaches should create tasks that allow athletes to explore rather than follow rigid repetitions. 1:11:48 – Programming principles and adjusting training to the individual Jarod adjusts cycles based on athlete readiness rather than fixed rules. He focuses on how athletes respond to stress rather than the stress itself. Training should follow the athlete's progression of competence and confidence, not arbitrary timelines. He prefers a flexible structure where principles guide but the athlete determines the pace. 1:19:40 – Coaching philosophy, communication, and what athletes need Jarod highlights that coaching is not about showing off knowledge but helping someone move better. He builds trust through communication and clarity rather than overwhelming athletes with science. He believes athletes need environments that reward curiosity and creativity. The coach creates the environment, but the athlete creates the movement. Jarod Burton Quotes “If I can teach the principle, the application can change, and the athlete can adapt.” “Good movement should feel rhythmic and natural, not forced.” “The environment will teach the athlete faster than a paragraph of cues.” “When an athlete stops trying to make the movement pretty, it usually starts to become pretty.” “The weight room supports speed. It should not compete with speed.” “Breathing gives athletes access to positions they did not know they had.” “Adaptable athletes win. Rigid athletes break.” “Coaching is about creating options for the athlete, not limiting them.” “I want athletes who can solve problems, not just follow instructions.” “Trust comes from communication, not complexity.” About Jarod Burton Dr. Jarod Burton is a chiropractor and sports performance coach who lives in the intersection of clinical practice, neuroscience, and high-performance human movement. A student of neurology and motor learning, Jarod works to uncover the hidden nervous system constraints that influence posture, coordination, elasticity, and power expression in sport. His methods combine manual therapy, joint mapping, sensory integration, and movement-based diagnostics to create individualized solutions that free up range, recalibrate neural rhythm, and unlock athletic speed, strength, and resilience. Jarod is passionate about a holistic philosophy of performance; one where the brain, body, and environment work in concert to reveal the best version of the athlete.

An Explosive Debate on Trump's Brain. Dr. John Gartner, former Johns Hopkins psychiatry faculty member and a vocal critic of Donald Trump, joins Live From the Table. We challenge Gartner directly on his claims that Donald Trump is exhibiting malignant narcissism, psychopathy, and accelerating dementia. The debate spans science, politics, ethics, medical bias, and the media's treatment of both Trump and Biden. This episode includes extended transcript-verified clips, counter-arguments, and some of the most heated exchanges we've aired. Chapters below. Chapters 00:00 – Intro: Who is Dr. John Gartner? 01:00 – Goldwater Rule & Diagnosing Public Figures 03:20 – Trump, Narcissism & Malignant Personality Disorders 07:00 – Is Trump a Psychopath? Criminality, Lying & Abuse 11:20 – Noam Pushes Back: What Counts as Evidence? 14:15 – The Dementia Question: Language, Gait & Decline 16:55 – “He's Not the Same Man”: Claims From Former Officials 18:45 – Noam's Counterargument: Bolton, Kelly, McMaster, Woodward 22:30 – Cognitive Decline vs. Strategy: What's Real? 26:05 – Trump's Speeches Examined: Word Salad or Something Else? 29:30 – The “Skedaddle” Story & Loose Associations 33:00 – Kamala Harris, Biden & Claims of Asymmetrical Scrutiny 37:10 – Debate Clips: Biden Then vs. Now, Trump Then vs. Now 41:50 – Variability & Sundowning: How Dementia Presents 45:00 – Trump's Stamina vs. Trump's Disorganization 48:20 – Is This Cognitive Decline or Just Aging? 52:00 – Impulsivity, National Security & Dangerous Decision-Making 56:10 – The Hakeem Jeffries “Very Nice Man” Story 59:00 – Biden Wandering Clips & Why the Medical Community Stayed Silent 1:02:00 – Is Medical Bias Real? Noam Pushes Gartner 1:04:00 – Would Trump's Inner Circle Have Noticed Decline? 1:07:00 – Narcissism, Children & Why His Family Keeps Distance 1:10:00 – “Do You Feel Sympathy for Him?” 1:14:00 – Closing Thoughts & Invitation to Visit the Cellar

Welcome to the NeurologyLive® Mind Moments® podcast. Tune in to hear leaders in neurology sound off on topics that impact your clinical practice. In this episode, "Understanding Variability in Infantile Spasms Care," Christina Briscoe, MD, epileptologist at Boston Children's Hospital, discusses new multi-center findings on current treatment practices for infantile epileptic spasms syndrome (IESS). Briscoe outlines why first- and second-line therapies remain largely standardized, yet significant variability emerges once hormonal therapy and vigabatrin fail. She details the evidence gaps driving inconsistent third-line and fourth-line decision-making, including limited clinical trial data, uneven access to ketogenic diet programs and epilepsy surgery, and historically low industry investment in infant-specific trials. Additional discussion focuses on ongoing research from the Pediatric Epilepsy Research Consortium, national and global comparisons in treatment pathways, barriers to study scalability in rare pediatric epilepsies, and the practical challenges of implementing timely diagnosis and standardized care across diverse healthcare settings. Briscoe also highlights under-recognized issues such as incorporation of ketogenic diet and early surgical evaluation into treatment pathways, and emphasizes the need for broader infrastructure, funding, and multi-center collaboration to improve outcomes for children with IESS. Looking for more Epilepsy discussion? Check out the NeurologyLive® Epilepsy clinical focus page. Episode Breakdown: 1:05 – Origins of the study, need to pursue more standardized care in IESS 4:40 – Reasons behind treatment variability after first and second-line options 8:00 – What research is needed to guide sequencing and standardize care 12:05 – Neurology News Minute 14:30 – What makes IESS studies difficult and how infrastructure can improve 18:50 – Lesser-discussed gaps, including ketogenic diet and surgical evaluation The stories featured in this week's Neurology News Minute, which will give you quick updates on the following developments in neurology, are further detailed here: Positive Phase 3 OCEANIC-STROKE Data Position Asundexian for Upcoming FDA Submission FDA Approves New Intrathecal Administration Route for Spinal Muscular Atrophy Gene Therapy GLP-1 Semaglutide Fails to Outperform Placebo in Phase 3 EVOKE Trial of Alzheimer Disease Thanks for listening to the NeurologyLive® Mind Moments® podcast. To support the show, be sure to rate, review, and subscribe wherever you listen to podcasts. For more neurology news and expert-driven content, visit neurologylive.com.

On this episode we talk with Tommy Johnson, the owner of Primal 1 Baseball facility in Gaithersburg, MD. Tommy is a seasoned baseball coach with a unique journey from professional baseball to earning a doctorate in kinesiology. Tommy shares his deep dive into various training methodologies, biomechanics, and the importance of skill acquisition frameworks for player development.00:00 Introduction and Guest Background01:25 Tommy's Baseball Journey02:17 Rebranding and Business Evolution06:08 The Importance of Teamwork in Player Development11:51 Gateway to Skill Acquisition22:44 Strength and Conditioning Insights48:24 Sub-Max Training and Injury Risks48:51 Training Tendons with Isometrics49:25 Integrating Different Training Modalities50:55 The Importance of Apprenticeship52:20 Breathing and Biomechanics53:56 PRI and FRC in Pain Management54:44 Challenges with PRI and FRC55:32 The Role of Posture and Movement58:04 FRC and Athletic Performance01:04:14 The Spiral Line and Fascial Slings01:24:12 Perception and Reaction in Training01:30:38 Innovative Eye-Tracking Device for Athletes01:31:46 Perception and Performance in Sports01:32:45 Exploring Functional Variability01:33:35 Virtual Reality in Sports Training01:34:51 Visualization and Automaticity01:35:57 Biomechanics and Performance Anxiety01:37:30 The Role of Biomechanics in Skill Acquisition01:39:44 Ecological Dynamics and Target Connection01:42:28 Exploring and Exploiting Constraints01:44:44 The Interplay of Biomechanics and Performance01:51:35 Cultural Biomechanics and Training Adaptations02:08:15 Contextualizing Stats in Baseball02:08:46 Determining the Right Angles for Players02:09:01 Stages of Learning and Repetition02:09:32 Evaluating VBA and Player Performance02:10:37 Advanced Bat Tracking and Analysis02:12:10 Importance of Variability in Training02:12:27 Role of Coaches as Guides02:13:20 Integrating FRC into Hitting02:16:28 Challenges in Applying Motor Preferences02:17:40 Complexity in Movement and Training02:23:10 Importance of Contextual Learning02:41:53 Balancing Strategy and Mechanics02:46:33 Final Thoughts and Future DiscussionsIntro music by: Muellzy⁠⁠  / muellzymusic  ⁠⁠Support Us & learn more about Ecological Dynamics (links below)⁠Donate to Finding the Edge:⁠⁠⁠⁠ buymeacoffee.com/ftepod⁠⁠⁠⁠Ecological Dynamics ResourcesResources from Emergence a movement skill education company dedicated to helping coaches learn how to apply an ecological approach to understanding and developing movement skill.Get 7% off most courses by using code: Edge7Educational Products: ⁠⁠⁠⁠https://emergentmvmt.com/shop-2/⁠⁠⁠⁠Social MediaTwitter: ⁠⁠@Emergentmvmt⁠⁠Instagram: ⁠⁠@Emergentmvmt⁠⁠Patreon:⁠⁠   / ⁠⁠emergentmvmt⁠⁠⁠⁠  Follow Us!Join our Discord: ⁠⁠bit.ly/3a07z1B⁠⁠Find us on Twitter: @FTEpod@gboyum01@RobertFrey40@kyledupic@CoachgbakerSubscribe on Youtube: ⁠⁠⁠⁠⁠⁠⁠⁠@findingtheedge⁠

Today's guest is Bill Smart. Bill is a sport scientist and physical preparation coach specializing in elite fight-sports performance. As the founder of Smarter Performance and the Strength & Conditioning lead for the CORE MMA team, Bill integrates cutting-edge evidence with real-world high-performance systems to enable combat athletes to show up on fight day in optimal physiological condition. Much of the conversation in sports performance hinges on speed and power development, or conditioning, as a stand-alone conversation. Sport itself is dynamic and combines elements of speed, strength, and endurance in a dynamic space. Training should follow the same considerations to be truly alive and effective. In the episode, Bill shares his journey from cycling and rowing to combat sports. He discusses how long isometric holds develop both physical and mental resilience, and their implementation in his programming. The conversation dives into muscle-oxygen dynamics, integrating ISOs with conditioning, and how testing shapes his approach. Bill also explores flywheel eccentrics, fascicle-length development, and why sprinting is a key element for maintaining elastic power in elite fighters. Today's episode is brought to you by Hammer Strength and the Just Fly Sports Online Courses 30-50% off all courses until December 1, 2025. (https://justflysports.thinkific.com) Use code “justfly10” for 10% off the Vert Trainer Use code “justfly20” for 20% off of LILA Exogen Wearable resistance gear at www.lilateam.com View more podcast episodes at the podcast homepage. (https://www.just-fly-sports.com/podcast-home/) Timestamps 0:00 – Bill's coaching journey and early mentors 6:04 – The importance of movement observation and intuition 11:35 – Why athletes plateau and how to identify limiting factors 20:42 – Strength training principles that actually transfer 30:01 – Using movement variability and play in training 40:36 – Coaching communication and creating connection 52:09 – The role of curiosity and creativity in coaching longevity 1:00:55 – Key lessons from years of coaching experience Actionable Takeaways 6:04 – Movement observation and intuition Bill emphasizes that the best coaches develop a trained eye for movement by observing, not just testing. Watch athletes move in multiple contexts before prescribing anything. Look for how they transition between patterns, not only the end positions. Use video less for judgment and more for curiosity. What is the athlete trying to do? 11:35 – Identifying limiting factors Athletes plateau when coaches overemphasize one metric or capacity while ignoring the real constraint. Look beyond the weight room; technical or psychological factors often drive plateaus. Use minimal testing data to narrow focus rather than justify complexity. Sometimes the limiting factor is overcoaching. Let athletes fail and self-correct. 20:42 – Strength that transfers Transfer happens when strength work complements, not competes with, the sport's rhythm and intent. Prioritize strength that preserves elasticity and timing rather than just force output. Rotate exercises often enough to keep athletes adaptive, but not so often that they lose rhythm. Load movement patterns, not just muscles. Treat every lift as coordination under resistance. 30:01 – Variability and play in training Bill describes play as a teaching tool that restores creativity and problem-solving in athletes. Use small games, uneven surfaces, or timing constraints to build adaptable movers. Variability should be purposeful. Expand coordination bandwidth without losing technical intent. Schedule “uncoached” time in sessions where athletes explore movement freely. 40:36 – Coaching communication and connection Great coaching depends on trust and empathy before information transfer. Deliver feedback as collaboration,

230: Jen and Wendy, reading specialists and dyslexia practitioners, explain what set for variability is and why it's a skill even beginning readers need. Click here for this episode's show notes.Sign up for my free masterclass, 5 Essential Steps to Reach All Readers. Get my book, Reach All Readers! Looking for printable resources that align with the science of reading? Click here to learn more about our popular and affordable membership for PreK through 3rd grade educators.Connect with me here! Blog Instagram Facebook Twitter (X)

Energy expenditure is one of the most fundamental yet often misunderstood aspects of human physiology. A central question is whether there is a ceiling to how many calories we can burn, and what happens when activity levels approach that limit. Grasping these dynamics is essential for health professionals and researchers, as energy balance directly influences body weight regulation, metabolic health, and athletic performance. Emerging research shows that our bodies regulate calorie burn not in a fixed manner, but through adaptation and compensation, revealing that the “calories in vs. calories out” model is far more dynamic than it may first appear. In this episode, we revisit key insights from experts such as Dr. Herman Pontzer, Dr. Brent Ruby, Dr. Mark Hopkins, Dr. Eric Trexler, and Dr. Chris Melby. These perspectives cover how the body adapts to different levels of physical activity, the metabolic adjustments during weight loss (often called adaptive thermogenesis), and the concept of energy flux in weight maintenance. Note: This episode is one of our Premium-exclusive episodes. To listen to the full episode, you'll need to be a Premium subscriber and access the episode on the private Premium feed. Otherwise, you can hear a preview of the episode on the public feed of the podcast. Timestamps [03:36] Contrained model of energy expendiure [12:33] What is the ceiling of human energy expenditure? [13:05] Reconciling energy intake and expenditure [13:32] Variability in metabolic rates [15:16] Adaptive thermogenesis and weight loss [18:37] Metabolic adaptation explained [31:51] Energy flux and weight maintenance Resources Subscribe to Premium Go to sigmanutrition.com Article: The “Calories In, Calories Out” Confusion: A Comprehensive Guide to Understanding Energy Balance Included episodes: 208 – Herman Pontzer, PhD | Constrained Energy Expenditure Model & Evolutionary Biology of Energy Balance 124 – Brent Ruby, PhD | The Human Ceiling of Energy Expenditure 299 – Mark Hopkins, PhD | Compensatory Eating & Activity Energy Expenditure 377 – Herman Pontzer, PhD | Metabolism, Mitochondria & Measuring Energy Expenditure 484 – Eric Trexler, PhD | Is Metabolic Adaptation an Illusion? 318 – Chris Melby, DrPH | Impact of Energy Flux on Weight Management

Heart disease is the world's biggest killer—and it often strikes without warning. It's responsible for around 1 in 5 deaths in the US. While these figures are deeply worrying, heart disease is not inevitable.  Decades of research have unearthed many of the risk factors associated with heart health, like poor diet or a sedentary lifestyle. In this episode, Dr. Nour Makarem outlines the latest scientific discoveries in this field and unveils some less-familiar risk factors. Drawing from large-scale population data and the latest wearable tech, she uncovers what makes heart disease so hard to spot, and what we can do today to prevent it.  Nour is a cardiovascular epidemiologist at Columbia University, whose research focuses on how our behaviors—like sleep, stress, and daily rhythms—impact heart disease risk. Her research has helped shape the American Heart Association's Essential Eight guide to heart health. Unwrap the truth about your food

Nitric oxide might be the most important molecule you've never heard of. In this episode, molecular medicine pioneer Dr. Nathan Bryan, PhD reveals how this fleeting gas controls blood flow, brain health, immune defense, and even sexual function. We cover the science of nitric oxide, how lifestyle choices impact its production, and why it could hold the key to preventing age-related diseases like Alzheimer's. You'll learn simple daily strategies to boost your nitric oxide naturally—without falling for supplement marketing gimmicks. Follow Dr. Bryan @drnathansbryan Follow Chase @chase_chewning ----- In this episode we discuss... 00:00 – Introduction 01:00 – What is Nitric Oxide? 03:05 – Why Nitric Oxide is Short-Lived 05:34 – How Nitric Oxide Works 08:03 – Immune Defense & Nitric Oxide 09:50 – Symptoms of Low Nitric Oxide 15:11 – The American Lifestyle Problem 19:56 – Nitric Oxide for Performance & Recovery 24:06 – Cardiovascular Health & Longevity 26:03 – How the Body Produces Nitric Oxide 32:00 – Beetroot & Supplement Myths 34:04 – Two Steps to Boost Production 36:03 – Nasal Breathing & Humming 39:01 – Mouth Taping for Sleep & Nitric Oxide 41:52 – Oral Microbiome & Diet 44:46 – The Antacid Problem 49:40 – Variability in Vegetable Nitrate Levels 52:52 – Risks of Overproduction 54:40 – Nitrate/Nitrite Marketing Myths 58:34 – Cutting-Edge Research & Drug Development 01:03:08 – Dr. Bryan's Daily Optimization Protocol 01:07:52 – The Mindset of Doing Hard Things 01:10:38 – Living Ever Forward 01:11:44 – Nitric Oxide & ALS ----- Episode resources: Save an additional 15% on C15:0 essential fatty acid at https://www.Fatty15.com/everforwward  Save 20% on creatine gummies with code EVERFORWARD at https://www.LegionAthletics.com  Watch and subscribe on YouTube Get his book The Secret of Nitric Oxide

View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter In this episode from July 2022, Peter dives deep into the topic of bone health and explains why this is an important topic for everyone, from children to the elderly. He begins with an overview of bone mineral density, how it's measured, how it changes over the course of life, and the variability between sexes largely due to changes in estrogen levels. From there he provides insights into ways that one can improve bone health, from exercise to nutrition supplements to drugs. Additionally, Peter discusses what happens when one may be forced to be sedentary (e.g., bedrest) and how you can work to minimize the damage during these periods. While this original episode is an AMA, it is available in full to all listeners as a special rebroadcast. We discuss: Overview of bone health topics to be discussed [2:30]; Bones 101: bone function, structure, and more [6:15]; Bone mineral density (BMD), minerals in bone, role of osteoblasts and osteoclasts, and more [9:30]; The consequences of poor bone health [14:30]; The devastating nature of hip fractures: morbidity and mortality data [18:00]; Where fractures tend to occur in the body [23:45]; Defining osteopenia and osteoporosis [25:30]; Measuring BMD with DEXA and how to interpret scores [28:00]; Variability in BMD between sexes [35:15]; When should people have their first bone mineral density scan? [37:45]; How BMD changes throughout the life and how it differs between men and women [40:15]; How changes in estrogen levels (e.g., menopause) impact bone health [45:15]; Why HRT is not considered a standard of care for postmenopausal bone loss [49:00]; Factors determining who may be at higher risk of poor bone health [52:00]; Common drugs that can negatively impact BMD [55:45]; How children can optimize bone health and lay the foundation for the future [59:30]; Types of physical activity that can positively impact bone health [1:03:30]; How weight loss can negatively impact bone health and how exercise can counteract those effects [1:12:15]; Nutrition and supplements for bone health [1:16:00]; Pharmaceutical drugs prescribed for those with low BMD [1:18:45]; Impact of extreme sedentary periods (e.g., bedrest) and how to minimize their damage to bone [1:23:30]; and More. Connect With Peter on Twitter, Instagram, Facebook and YouTube