Podcasts about rct

Do you routinely order prophylactic antibiotics at time ofsecond-degree laceration repair? Is there data for that? While the use of prophylacticantibiotics “is reasonable” (per ACOG PB 198) for OASIS lacerations, what doesthe data look like for second degree lacs? Well, the answer is both supportiveAND non-supportive of that practice! In this episode, we will cover a brand newpublication (RCT) from BMJ on this very issue, and also highlight a meta-analysisfrom Plos One (May 2025) that also examined this question. Listen in fordetails!1.     ACOG PB 1982.     Armstrong H, Whitehurst J, Morris RK, HodgettsMorton V, Man R; CHAPTER group. Antibiotic prophylaxis for childbirth-relatedperineal trauma: A systematic review and meta-analysis. PLoS One. 2025 May9;20(5):e0323267. doi: 10.1371/journal.pone.0323267. PMID: 40344566; PMCID:PMC12064200.3.     Risk of infection and wound dehiscence after useof prophylactic antibiotics in episiotomy or second degree tear (REPAIR study):single centre, double blind, placebo controlled randomised trial. BMJ 2025; 391doi: https://doi.org/10.1136/bmj-2025-084312 (Published 29 October 2025): BMJ2025;391:e084312

The Seahawks extend their unbeaten road record to 10 wins under Mike MacDonald with an emphatic 38-14 win! Sam Darnold was dealing, JSN carries on his phenomenal season, the rookies get involved and the defence continues to prove it's elite! Join Mitch, Josh and our special guest 12 (all the way from Greece) Nikos Kardasilaris, as we break down the game including:

Un nouvel épisode du pharmascope est maintenant disponible! Dans de ce 102ème épisode, Nicolas, Sébastien et Isabelle discuteront de vitamine B12. Dans ce premier épisode d'une série de deux, on discute de manifestations cliniques, d'évaluation biochimique, d'approche diagnostique et de bénéfices (ou pas) du traitement d'un déficit en vitamine B12. Les objectifs pour cet épisode sont les suivants: Identifier les patients avec une indication de doser la vitamine B12 Discuter de la fiabilité du dosage de la vitamine B12 Discuter de l'approche diagnostique du déficit en vitamine B12 Expliquer les bénéfices d'un supplément de vitamine B12 dans le traitement et la prévention de diverses conditions   Ressources pertinentes en lien avec l'épisode Boughrassa F, Framarin A. Usage judicieux de 14 analyses biomédicales: Outil pratique. Institut national d'excellence en santé et services sociaux. Avril 2014. Solomon LR. Cobalamin-responsive disorders in the ambulatory care setting: unreliability of cobalamin, methylmalonic acid, and homocysteine testing. Blood. 2005;105:978-85. Hunt A, Harrington D, Robinson S. Vitamin B12 deficiency. BMJ. 2014;349:g5226. Stabler SP. Clinical practice. Vitamin B12 deficiency. N Engl J Med. 2013;368:149-60. Didangelos T et coll. Vitamin B12 Supplementation in Diabetic Neuropathy: A 1-Year, Randomized, Double-Blind, Placebo-Controlled Trial. Nutrients. 2021;13:395. Dangour AD et coll. Effects of vitamin B-12 supplementation on neurologic and cognitive function in older people: a randomized controlled trial. Am J Clin Nutr. 2015;102:639-47. McCleery J et coll. Vitamin and mineral supplementation for preventing dementia or delaying cognitive decline in people with mild cognitive impairment. Cochrane Database Syst Rev. 2018;11:CD011905. Rutjes AW et coll. Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late life. Cochrane Database Syst Rev. 2018;12:CD011906. Kwok T et coll. A randomized placebo-controlled trial of using B vitamins to prevent cognitive decline in older mild cognitive impairment patients. Clin Nutr. 2020;39:2399-2405. Kwok T et coll. A randomized placebo controlled trial of vitamin B12 supplementation to prevent cognitive decline in older diabetic people with borderline low serum vitamin B12. Clin Nutr. 2017;36:1509-1515. Van der Zwaluw NL et coll. Results of 2-year vitamin B treatment on cognitive performance: secondary data from an RCT. Neurology. 2014;83:2158-66. Almeida OP et coll. B vitamins to enhance treatment response to antidepressants in middle-aged and older adults: results from the B-VITAGE randomised, double-blind, placebo-controlled trial. Br J Psychiatry. 2014;205:450-7.

Send us a textI unpack what “ultra-processed” really means, why these foods are so easy to overeat, what the best evidence shows (including metabolic-ward studies), and how I personally navigate them without fear or perfectionism. Key topics & evidence (in plain English):What counts as “ultra-processed”? I walk through the NOVA system—useful, not perfect—and where borderline items (frozen meals, boxed mixes) fit. See an overview of NOVA classifications here. How we got here: post-WWII abundance of refined flour, cheap sugars, oils, and a cultural push for convenience—now ~60% of the U.S. diet comes from UPFs (study). Additives: stabilizers, emulsifiers, preservatives, and colors are generally recognized as safe (GRAS). I explain why, on their own, they're probably not the main health issue. The bigger problem: UPFs are energy-dense, engineered for bliss (fat/sugar/salt + perfect texture), and easy to eat quickly—driving higher calorie intake.  • Metabolic-ward crossover trial: +~508 kcal/day when participants ate UPFs vs minimally processed (Cell 2019). • Overweight adults in a crossover design: +~814 kcal/day on the UPF week (PubMed). • Another recent crossover RCT reports ~300 kcal/day higher on UPFs (Nature Medicine 2025). What I recommend (and what I do):Prioritize whole foods most of the time; shop the perimeter; cook when you can. Canned tomatoes/beans and frozen fruits/peas are fine helpers. If weight, diabetes, or blood pressure are concerns, be extra cautious with UPFs—they're designed to be irresistible and calorie-dense. Moderation wins: I enjoy favorites (yes, even boxed mac 'n' cheese and crunchy peanut butter) without letting them dominate my plate. Takeaways you can use today:Build meals around minimally processed proteins, veggies, fruits, and beans; let convenience items support—not star—in your diet. Watch “calorie-dense + easy to overeat” combos (chips, sweets, fast food). If you have them, portion once, then put the package away. If symptoms or inflammation are puzzling you, try a short UPF-light experiment (2–4 weeks) and see how you feel. If this episode helped, please follow and leave a quick review—and share it with a friend who's curious about UPFs. For my newsletter and resources, visit drbobbylivelongandwell.com.

The Seahawks are 5-2 at the bye week. Join Mitch, Josh, Dan and Bryce as they discuss:

L'équipe des Causeries propose un debrief du match contre Toulouse, mais surtout, prend très vite de la hauteur (et quelques bulles pétillantes) pour proposer une émission apéro qui balaie toute l'actu du RCT en détail, et sans se prendre au sérieux. Hébergé par Acast. Visitez acast.com/privacy pour plus d'informations.

"What a strange game!" Sam Darnold, Seattle Seahawks QB 2025Join us for our 12 Talk X Hawks Eye Podcast crossover special. Mitch, Josh and Bryce will be breaking down the Seahawks vs Texans game including:

Les Causeries de la rade reviennent sur la victoire bonifiée du RCT face au Racing 45-21L'équipe reviendra également sur les blessures de Frisch et Serin, ainsi que sur la rumeur transfert : Guillaume CramontEt le débat de la semaine : Gestion de l'effectif : Toulon joue-t-il avec le feu ? Hébergé par Acast. Visitez acast.com/privacy pour plus d'informations.

The Seattle Seahawks flew to sunny Florida and put on a clinic against the high-flying Jacksonville Jaguars! Join Mitch, Josh and special guest co-host, Discord Member and Welsh Seahawks fan Richard Blake as we break down the game including:

Send us a textVisit my websiteCan a positive mindset truly improve your health—or even help you beat disease? In this episode, Dr. Bobby and guest Sean McDevitt explore the evidence behind optimism, visualization, and prayer to uncover what really works.In today's episode of Live Long and Well, Dr. Bobby is joined by fitness and life coach Sean McDevitt to explore whether positive thinking can influence health outcomes. They dive into both anecdotal and clinical evidence, starting with sports psychology and then navigating the science behind mindset and disease. The conversation opens with laughter and smiles—literally. Inspired by Norman Cousins' Anatomy of an Illness, Dr. Bobby references a meta-analysis showing genuine smiling does, in fact, temporarily boost happiness, while artificial smiling (like holding a pen in your mouth) doesn't.They begin with sports, where 86 studies show that visualizing athletic success can improve performance in agility, strength, and game-specific skills. Next, they ask a deeper question: does having a positive attitude affect the progression of serious disease? A meta-analysis of 26 studies on life satisfaction and longevity suggests happy people may live longer—especially when it comes to heart health. Optimism, for instance, was linked to a 35% reduction in cardiovascular events and a 15% decrease in all-cause mortality.However, when it comes to cancer, the picture gets murkier. A review of 165 studies links stress to poorer survival, but a separate meta-analysis on coping styles found no consistent impact on recurrence or survival. One influential study on breast cancer patients even found that while helplessness predicted worse outcomes, having a “fighting spirit” made no significant difference (source). As Dr. Bobby notes, it's important not to burden patients with guilt if they can't “stay positive.”The critical question becomes: if you're not naturally optimistic, can you cultivate positivity—and will it help? Encouragingly, several intervention studies suggest it might. One trial showed cardiac markers improved after optimism training, and a meta-analysis of 56 RCTs found a 15% boost in immune function after psychological interventions. A small MS study linked mindfulness to better walking ability, and a large RCT on breast cancer showed a 45% drop in recurrence with stress-reduction and mood-enhancing strategies.Finally, the episode touches on spirituality. While many find comfort in prayer, evidence from an RCT of 800 ICU patients and a [meta-analysis] shows no significant impac

Tony is back in the Game Lounge with the Speedrunner and Twitch Streamer that got Roller Coaster Tycoon into Summer Games Done Quick 2025, Dynomation! The two of them talk about all strategies that go into an RCT speedrun, what it was like creating some of the routes, and his work for other speedrunning marathons like Zeldathon! They also cover the Tokyo Game Show 2025, and the September 24th PlayStation State of play amongst all the other headlines in the gaming world over the last 2 weeks, and the upcoming game releases!Follow Tony: https://www.twitch.tv/tonysgameloungeYouTube: https://www.youtube.com/@TonysGameLounge--------------------------------------------------------Follow Dynomation: https://www.twitch.tv/dynomationBluesky: https://bsky.app/profile/dynomation.bsky.social--------------------------------------------------------Join the Official Tony's Game Lounge Discord: https://discord.gg/xXyvjaCsXp

A major scientific review looked at the best available evidence on apple cider vinegar (ACV) and its effects on body weight. Researchers combined the results from 9 different studies that included adults who were overweight, obese, or had type 2 diabetes.Here's what they found:• Taking ACV daily was linked to a significant drop in body weight, BMI, and waist size.• The authors calculated this could amount to an average weight loss of about 7.4 kg (over 16 pounds).• The most effective approach seemed to be taking about two tablespoons (30 mL) per day for up to 12 weeks.The main takeaway is that science suggests ACV may be a helpful tool for short-term weight management.Disclaimers:"This information is for educational purposes only and should not be interpreted as medical advice.""The study discussed is a meta-analysis of randomized controlled trials conducted on adult humans who were overweight, obese, or had type 2 diabetes. The intervention periods in the included studies were relatively short, ranging from 4 to 12 weeks.""Always consult with a qualified healthcare professional before making any changes to your diet, supplement regimen, or treatment plan, especially if you have a medical condition or are taking medications.""This channel does not provide medical advice."#AppleCiderVinegar #WeightLoss #BodyComposition #MetaAnalysis #ObesityResearchSource Article Citation:Castagna, A.; Ferro, Y.; Noto, F.R.; et al. Effect of Apple Cider Vinegar Intake on Body Composition in Humans with Type 2 Diabetes and/or Overweight: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Nutrients 2025, 17, 3000. DOI: https://doi.org/10.3390/nu17183000 Apple cider vinegar, ACV, acetic acid, weight management, body composition, obesity, overweight, type 2 diabetes, meta-analysis, randomized controlled trial, RCT, body weight, BMI, body mass index, waist circumference, visceral adiposity, anthropometric measurements, weight loss, dietary supplement, short-term weight management, metabolic health, adiposity, nutritional intervention, systematic review, dose-response

Dans cet épisode, les Causeries de la Rade reviennent sur la victoire bonifiée contre Pau, qui positionne le RCT dans le trio de tête malgré un match de retard.L'occasion aussi d'un dossier transferts : Serin et White vers la prolongation, Menoncello vers Toulouse et ce débat : Toulon est-il toujours attractif ? Hébergé par Acast. Visitez acast.com/privacy pour plus d'informations.

Get My Book On Amazon: https://a.co/d/avbaV48DownloadThe Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/1 On 1 Coaching Application: https://hunterwilliamscoaching.carrd.co/Book A Call With Me: https://hunterwilliamscall.carrd.co/Supplement Sources: https://hunterwilliamssupplements.carrd.co/Amazon Storefront: https://www.amazon.com/shop/hunterwilliams/list/WE16G2223BXA?ref_=cm_sw_r_cp_ud_aipsflist_R7QWQC0P1RACB2ETY3DYSocials:Instagram: https://www.instagram.com/hunterwilliamscoaching/Podcast: https://hunterwilliamspodcast.buzzsprout.com/Video Topic Request: https://hunterwilliamsvideotopic.carrd.co/I break down the human data on HGH (human growth hormone) for anti-aging and performance—what actually improves, what doesn't, and where it clearly helps (injury recovery and true GH deficiency). I also cover side effects, dosing philosophy (“replacement, not enhancement”), and how to think about HGH in a longevity stack as you age.Timestamps0:00 - Intro, goal of the video and who this is for2:10 - What HGH is and age-related decline (somatotropin refresher)3:28 - The Rudman 1990 study and “turning back the clock” claims4:26 - 1994–1996 trials: lean mass up, strength/endurance unchanged5:00 - 2002 Blackman RCT + meta-analysis: +2 kg lean, −2 kg fat7:00 - Side effects: edema, joint pain, carpal tunnel, insulin resistance (dose-dependent)8:38 - Athletic performance evidence: banned in sport, but does it help?10:06 - WADA/Stanford findings: sprint bump, no strength/endurance gains12:20 - Injury & healing overview: why HGH could help tissue repair12:36 - Burn-healing data: faster closure and shorter stays (with hyperglycemia risk)13:48 - Fracture healing: tibial fracture RCT, closed vs. open outcomes15:28 - ACL surgery study: better knee extensor strength without bigger muscles17:02 - Adult GH deficiency (AGHD): signs, causes, quality-of-life impact18:48 - Early AGHD trials (1989–1990): composition, VO₂, well-being improvements19:40 - 2000s–today: cardio risk markers, aerobic capacity, long-term outcomes20:34 - Who benefits most: AGHD/older adults vs healthy/athletes25:08 - Replacement vs enhancement: practical dosing philosophy26:00 - Final verdict: where HGH fits in a longevity stack27:14 - New studio, channel update, and closing thoughts

How Workshops Win: Emotion-First Public Speaking for Cash-Based PT Lead Gen In this episode, Doc Danny Matta lays out how to fill your schedule by getting in front of real people—workshops, talks, and small group education—and connecting emotionally before you ever ask for the appointment. He explains direct-response marketing for cash-based clinics, the “feelings before logic” rule, and a practical script stack (frustration → “imagine if” → personal story → action) that turns talks into patients. Quick Ask Help PT Biz move toward the mission of adding $1B in cash-based services to our profession: share this episode with a clinician friend or post it to your IG stories and tag Danny—he'll reshare it. Episode Summary Direct-response > referrals: Cash clinics grow fastest by going straight to the people (gyms, clubs, teams, parent groups), not by waiting on physician referrals. Workshops convert: Live education (in-person or virtual) is a predictable way to create trust and book consults. Feelings before facts: Lead with frustration, fear, and hope—the human stuff—then layer in the plan. Positive vision beats fear: “Imagine if…” scenarios help audiences see the future they want and move toward it. Stories sell: Personal experience (e.g., your own injury journey) creates instant credibility and connection. Let them say it: When attendees voice their own stakes and frustrations, commitment skyrockets. The Emotional Connection Framework Appeal to feelings before logic. Name the frustration in their language (“Isn't it frustrating when…?”) to open the door to change. Use “Imagine if…” Paint a clear, positive future state (pain-free golf trips, finishing workouts, keeping up with kids). Share something personal. Brief, relevant story that mirrors their journey (e.g., your own ACL rehab or chronic pain lesson). Make them feel the problem. Skip the RCT lecture; speak to missed experiences and what they're giving up. Elicit their why. Ask direct questions so they articulate what's at stake—then show the next step. Field Notes & Examples Workshops that work: Gyms, run clubs, golf leagues, youth sports parents, corporate wellness lunches, and private FB groups. The “gruff granddad” story: A patient's Disney scooter and coaster seatbelt moment became the emotional turning point—once he said it, change followed. Military → MobilityWOD/CrossFit reps: Coaching, audits, and “mystery shopper” feedback sharpened delivery—reps matter. Pro Tips You Can Use Today Book two talks this month. One in person, one virtual. Keep each to 25–30 minutes + Q&A. Script the open. 90 seconds: frustration opener → “imagine if” vision → your 20-second origin story. Give a simple plan. 3 steps max. Clear, doable, no jargon. Single CTA. “Grab a free 15-minute consult today”—QR code + signup sheet + link. Debrief after. What hook landed? What question came up most? Tighten the next talk. Notable Quotes “If you want action, connect emotionally first. Feelings open the door; logic walks them through it.” “I'd rather pull people toward the future they want than push them with fear. ‘Imagine if…' changes the room.” “When they say what hurts and what they want back, commitment follows.” Action Items Create a 1-page workshop outline: opener, 3 teaching points, 1 CTA. Make a list of 10 local/digital groups and pitch your talk this week. Design a QR code to your consult page and practice the closing script. Track: attendees → consults → plans of care. Iterate monthly. Programs Mentioned Clinical Rainmaker: Coaching + plan to get you full-time in your clinic. Mastermind: Scale beyond yourself into space, team, and systems. PT Biz Part-Time to Full-Time 5-Day Challenge (Free): Get crystal clear on expenses, visit targets, pricing, 3 go-full-time paths, and a one-page plan. Resources & Links PT Biz Website Free 5-Day PT Biz Challenge About Danny: Over 15 years in the profession—staff PT, active-duty military PT, cash-practice founder and exit—now helping 1,000+ clinicians start, grow, and scale cash-based practices with PT Biz.

message me: what did you take away from this episode? Ep 103  (http://ibit.ly/Re5V) Christine Catling on choosing home births, workforce sustainability and interdisciplinary advantages@PhDMidwives #research #midwifery  #education #birthsetting #homebirth #UTS #ACM #workforceresearch link - t.ly/XwoCOhttps://australianmidwiferyhistory.org.au/A purple-striped uniform, a corridor of hand-drawn portraits, and a decision that changed everything. That's where Christine Catling starts—then she takes us through three decades of midwifery identity, home birth advocacy, and the quiet systems that make or break trust. We follow her move from UK nursing to Australian midwifery, the spark that led to a qualitative PhD on why women choose home birth, and the national consortium that helped publicly funded home birth services grow across Australia. The pattern is clear: when people feel seen and valued, services improve; when they don't, the costs—human and financial—compound.We dive into the workforce crunch with blunt honesty. Why are midwives leaving between years three and five? What does it cost to lose skills and continuity just as clinicians hit their stride? Christine shares promising findings from a cluster RCT on group clinical supervision and argues for cost analyses that count retention, recruitment, agency use, and the ripple effects on safety. The conversation also tackles freebirth and distrust of institutional care, not with judgment but with a hard look at what it takes to rebuild trust: first impressions that centre the person, informed consent that's real, and models of care that let midwives do midwifery.Along the way, you'll hear how interdisciplinary work sharpens policy, why shared decision-making around induction and elective caesarean is a safeguard, and how compassion—eye contact, presence, a name—can change outcomes in seconds. We end with momentum: papers in the pipeline, global conversations with UK professional midwifery advocates, and a push to turn evidence into resourced policy that keeps midwives and families safer. If you care about midwifery, home birth, workforce sustainability, and humane care that actually works, this one's for you.Enjoyed the conversation? Follow, share with a colleague, and leave a quick review—what's the one change you'd fund tomorrow to support midwives? Support the showDo you know someone who should tell their story?email me - thruthepodcast@gmail.comThe aim is for this to be a fortnightly podcast with extra episodes thrown inThis podcast can be found on various socials as @thruthepinardd and our website -https://thruthepinardpodcast.buzzsprout.com/ or ibit.ly/Re5V

Dans cet épisode, les Causeries de la Rade débriefent la défaite à Bayonne in extremis, avec un focus particulier sur les aspects tactiques.L'occasion aussi de revenir sur la grosse victoire des Espoirs contre Narbonne.Et enfin, un gros dossiers transferts : demi de mêlée, ouvreur, deuxième ligne, ça bouge au RCT ! Hébergé par Acast. Visitez acast.com/privacy pour plus d'informations.

A close win in the Desert for the Seahawks! Join Josh with special guest co-host and host of @intheendzoneuk, Dom Ainley, as we break down the Seattle Seahawks vs the Arizona Cardinals game.You can follow In The Endzone UK on:SpotifyInstagram - @intheendzoneukHelp grow the 12 Talk Community by liking, subscribing, sharing and hitting the notification bell to stay up to date on new episodes and guest appearances. You can also follow us on our social media channels:

SEAHAWKS SHOW WHAT WE'VE ALL BEEN HOPING FOR! The Seattle Seahawks win 44-13 against the New Orlean Saints and it was a heck of a game in all 3 phases! Join Mitch, Josh and our special guest 12, Jonas Meister (German Sea Hawkers) as we break down the game including:

March of Dimes Research Center for Advancing Maternal Health Equity investigator Dr. Sindhu Srinivas and doula Alexia Doumbouya discuss leading a randomized controlled trial (RCT) on whether doula integration throughout pregnancy, birth, and postpartum can decrease maternal depression and anxiety.

Do Child Friendly Spaces (CFS) really improve children's mental health?Child-Friendly Spaces (CFS) are safe, structured places established quickly in emergencies where children can play, learn, and receive psychosocial support, to promote protection and wellbeing.In this second episode, Sarah Harrison, Acting Director of the Red Cross Red Crescent Movement MHPSS Hub, speaks with Professor Alastair Ager, Queen Margaret University and Columbia University and Phiona Koyiet, MHPSS Lead, World Vision International, for a practitioner-focused reflection.Together they examine what the evidence says about effectiveness and impact of CFS for children's wellbeing, protection and mental health, drawing on rigorous research (see below) and unpack what this means in practice: setting and monitoring quality indicators, ensuring skilled facilitators (“animators”), and the importance of integrating CFS within a tiered system of care with clear referral pathways - since CFS are not ‘silver bullets'. They discuss field adaptations, cultural relevance, costs and staffing, and how evidence has shaped World Vision's programming guidance.Key resources for practitionersTools and guidance for monitoring and evaluating Child Friendly SpacesThe Toolkit for Child Friendly Spaces in Humanitarian SettingsRead more about the research:Evaluating the longer-term mental health, developmental and systems impact of Child Friendly Spaces in humanitarian emergencies An RCT of enhanced Child Friendly Space interventions for children affected by conflict and displacementEvidence from the Frontline: Mental Health in Crisis-Affected Contexts is a six-episode mini-series produced in collaboration between the MHPSS Hub and Elrha, designed for practitioners working in humanitarian and crisis contexts, the series highlights impactful interventions and practical insights from experts in the field. 

Continuing our AACPDM 2025 Preview series!Effect of high-frequency, low magnitude vibration on physical activity and physical function in children with cerebral palsy: a randomised controlled trialThis paper is a contender for the AACPDM's highest abstract honour - the Gayle G Arnold Award!There is still time to register for the conference in beautiful New Orleans - Visit https://www.aacpdm.org/events/2025 for all the details!

Stress isn't just something to “manage” — it's a signal, a teacher, and often, an invitation to look deeper at our health, our choices, and our lives. In this solo episode, Darin reframes stress not as an enemy, but as a dashboard light pointing toward misalignments in our nervous system, environment, relationships, and purpose. Drawing on science, practical tools, and personal insight, Darin reveals how layered stress silently drains our vitality — and how to transform it into an ally for growth, healing, and deeper contentment. Whether it's hidden trauma, toxic environments, unresolved conflict, or the modern distractions constantly pulling at our attention, Darin lays out a roadmap to stop the leaks and reclaim the energy already within you. This episode is a powerful reminder: stress isn't the end of the story — it's the beginning of awareness, safety, and a super life.     What You'll Learn in This Episode [00:00] Introduction to the Super Life podcast [03:27] Why stress might not be your enemy [04:17] Stress as an ally: the signals it gives us about misalignment [04:32] The dashboard light metaphor: how stress reveals hidden issues [05:28] The illusion of “no choice” and the infinite possibilities always available [06:12] Global stress statistics and why most people underestimate their stress load [07:23] Hidden stress revealed through heart rate variability and physiology [08:23] Layered stress: how sleep, exercise, and poor choices compound each other [09:25] Safety vs. calm — why your nervous system craves safety first [10:15] Trauma and the unconscious mind: how old wounds drive our stress response [11:54] Inner narratives and negative self-talk as hidden stress multipliers [12:22] The role of community and your social field in stress and resilience [13:53] Relationships, honesty, and how your circle shapes your energy [14:55] Why boundaries around media and politics are vital for mental clarity [17:42] Finding micro-purpose when life feels overwhelming [18:52] Environmental layers of stress — light, air, and clutter [19:15] The existential layer: stress from living without service or purpose [20:12] Stress as a risk amplifier — how it undermines healing and health [20:55] The deeper truth of safety, connection, and higher power [23:00] Practical tools: breathing, grounding, nature, and conscious choices [24:01] Trauma reframed: not a problem, but a protector at the time [25:25] Lessons from Peter Levine and wild animals: releasing trauma physically [26:04] Questions to ask trauma: “What are you protecting me from?” [26:56] Stress as a multiplier of aging, disease, and poor outcomes [29:20] Why stress isn't a single cause — it's layered and chronic [30:18] Anti-stress strategies: circadian rhythm, nature, and gratitude [31:49] Energy leaks to avoid: clutter, poor food, scrolling, bad boundaries [32:22] What matters most: service, contribution, and alignment [33:28] Final toolkit: breathwork, movement, nature, sleep, and gratitude [34:38] The deeper invitation: step into sovereignty and live your SuperLife     Thank You to Our Sponsors: Manna Vitality: Go to mannavitality.com/  or use code DARIN20 for 20% off your order. Bite Toothpaste: Go to trybite.com/DARIN20 or use code DARIN20 for 20% off your first order.     Find More from Darin Olien: Instagram: @darinolien Podcast: SuperLife Podcast Website: superlife.com Book: Fatal Conveniences Check out my podcast with Dr. Amy Abbington     Key Takeaway “Stress is not the enemy. It's a dashboard light — a teacher showing you where you're out of alignment. When you reframe stress, you reclaim your energy and create space for healing, safety, and the joy of living a super life.”     Bibliography (selected, peer-reviewed) Sources: Gallup Global Emotions (2024); Gallup U.S. polling (2024); APA Stress in America (2023); Natarajan et al., Lancet Digital Health (2020); Orini et al., UK Biobank (2023); Martinez et al. (2022); Leiden University (2025). Cohen S, Tyrrell DA, Smith AP. Psychological stress and susceptibility to the common cold. N Engl J Med.1991;325(9):606–612. New England Journal of Medicine Cohen S, et al. Chronic stress, glucocorticoid receptor resistance, inflammation, and disease risk. Proc Natl Acad Sci USA. 2012;109(16):5995–5999. PNAS Kiecolt-Glaser JK, et al. Slowing of wound healing by psychological stress. Lancet. 1995;346(8984):1194–1196. The Lancet Kiecolt-Glaser JK, et al. Hostile marital interactions, proinflammatory cytokine production, and wound healing.Arch Gen Psychiatry. 2005;62(12):1377–1384. JAMA Network Tawakol A, et al. Relation between resting amygdalar activity and cardiovascular events. Lancet.2017;389(10071):834–845. The Lancet Epel ES, et al. Accelerated telomere shortening in response to life stress. Proc Natl Acad Sci USA.2004;101(49):17312–17315. PNAS McEwen BS, Stellar E. Stress and the individual: mechanisms leading to disease. Arch Intern Med.1993;153(18):2093–2101. PubMed McEwen BS, Wingfield JC. Allostasis and allostatic load. Ann N Y Acad Sci. 1998;840:33–44. PubMed Felitti VJ, et al. Relationship of childhood abuse and household dysfunction to many leading causes of death in adults (ACE Study). Am J Prev Med. 1998;14(4):245–258. AJP Mon Online Edmondson D, et al. PTSD and cardiovascular disease. Ann Behav Med. 2017;51(3):316–327. PMC Afari N, et al. Psychological trauma and functional somatic syndromes: a systematic review and meta-analysis.Psychosom Med. 2014;76(1):2–11. PMC Goyal M, et al. Meditation programs for psychological stress and well-being: a systematic review and meta-analysis. JAMA Intern Med. 2014;174(3):357–368. PMC Qiu Q, et al. Forest therapy: effects on blood pressure and salivary cortisol—a meta-analysis. Int J Environ Res Public Health. 2022;20(1):458. PMC Laukkanen T, et al. Sauna bathing and reduced fatal CVD and all-cause mortality. JAMA Intern Med.2015;175(4):542–548. JAMA Network Zureigat H, et al. Physical activity lowers CVD risk by reducing stress-related neural activity. J Am Coll Cardiol.2024;83(16):1532–1546. 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In this solo episode, Darin shares everything he's learned over nearly a decade of caring for his beloved German Shepherds, Chugga and Ella. From water quality to food choices, stress management, natural therapies, and even stem cells, Darin reveals the daily practices and integrative care strategies that keep his dogs thriving. With inspiration from Forever Dog authors Rodney Habib and Dr. Karen Becker, this episode is packed with actionable steps and powerful reminders about what it means to be a true steward for our animal companions. What You'll Learn in This Episode [00:00] Welcome and introduction – why this episode is dedicated to dogs and animal care [00:40] The bond with Chugga and Ella and why stewardship matters [01:16] Inspiration from The Forever Dog and leading longevity experts [01:38] Clean water: why filtration is critical for pets and how Darin prepares it [03:01] How much water your dog really needs and the danger of dehydration [03:38] A scary heatstroke story with Ella and the importance of paying attention [04:11] Daily care tips: washing bowls, using stainless steel, and avoiding bacteria buildup [04:43] Electrolytes, minerals, and using natural supplementation for dogs' hydration [05:35] Food choices: balancing plant-based with raw diets using Bramble and Viva Raw [07:01] The Dog Aging Project: why feeding once a day may extend longevity [08:12] Transitioning from kibble to raw: microbiome, gut diversity, and safety tips [09:47] Adding veggies, pumpkin, sweet potatoes, and berries for diversity and antioxidants [11:40] The importance of walks, exercise, and letting dogs sniff for cognitive health [12:27] Training, discipline, and running with Chugga on the mountain bike [13:32] How dogs mirror our stress and why managing your own health impacts theirs [14:01] Working with the endocannabinoid system, CBD, and reducing nervous tension [15:03] Natural therapies: PEMF mats, AmpCoil, red light, and energy balancing [16:08] Conventional vs naturopathic care—when to use both for acute and long-term health [17:00] Chugga's autoimmune challenges and the integrative approach to healing [18:20] Modalities used: stem cells, acupuncture, microbiome testing, ozone baths, and more [20:34] How pets reflect back our stress and why healing ourselves heals them too [22:07] Building a holistic health protocol: food, supplements, exercise, trauma release [23:05] Why meal timing and fasting windows can boost detox and longevity in dogs [25:11] Daily practices: washing bowls, diversifying food, hydration, and routines [26:29] The role of the endocannabinoid system in pets and humans alike [27:27] Alternative therapies: psychic readings, EFT, remote healing, and staying open [28:10] Back to basics: food, water, exercise, sleep, and trauma release for pets and people [28:41] Final reflections: stewardship, love, and why pets are free beings bonded to us Thank You to Our Sponsors: Our Place: Toxic-free, durable cookware that supports healthy cooking. Use code DARIN for 10% off at fromourplace.com. Find More from Darin Olien: Instagram: @darinolien Podcast: SuperLife Podcast Website: superlife.com Book: Fatal Conveniences Key Takeaway “Our dogs are barometers for our own well-being. When we reduce toxins, diversify food, manage stress, and honor them as family, they not only thrive longer — they remind us how to live better ourselves.” Bibliography / Sources Water & nutrition guidance WSAVA Global Nutrition—pet food selection & toolkit; Merck Veterinary Manual—typical daily water needs. WSAVA+1MSD Veterinary Manual Feeding frequency Bray EE et al. “Once-daily feeding is associated with better health in companion dogs” (Dog Aging Project, GeroScience 2022). PMCPubMedDog Aging Project Activity & cognition Dog Aging Project analyses on physical activity and cognitive health in older dogs (GeroScience 2022). ResearchGate Raw diets: microbiome & safety Sandri M. et al., BMC Vet Res 2016; Schmidt M. et al., PLOS ONE 2018; Xu J. et al., 2021; Davies RH. et al., 2019 (review on raw diets & pathogens). BioMed CentralPLOSPMC+1 Plant-based diets for dogs Knight A. et al., PLOS ONE 2022. PMC Microbiome testing (clinical tool) Texas A&M GI Lab—Dysbiosis Index overview. AVMA Owner–dog connection, stress & oxytocin Roth L. et al., Scientific Reports 2019 (stress synchrony); Wilson C. et al., PLOS ONE 2022 (dogs smell human stress); Nagasawa M. et al., Science 2015 (oxytocin gaze loop). NaturePMCPubMed Stem cells for canine OA Harman R. et al., Front Vet Sci 2016 (RCT, allogeneic ADSCs); Cuervo B. et al., Int J Mol Sci 2014 (randomized); VetEvidence 2022 (knowledge summary). FrontiersPMCVeterinary Evidence Acupuncture / gold bead studies & reviews Baker-Meuten A. et al., 2020 (prospective OA); Teixeira LR. et al., JAVMA 2016; Jaeger GT. et al., Vet Rec 2006. PMCAVMA JournalsPubMed Photobiomodulation (red light) AVMA Journals RCT in canine hip OA (2022). DVM 360 PEMF Randomized post-op pain/IVDD trial (NC State coverage); Front Vet Sci 2021 (targeted PEMF). NC State NewsFrontiers Chiropractic / manipulation Randomized Boxer puppy study (spondylosis); systematic review of manipulative therapies; AVMA policy context. PMC+1AVMA Ozone & IV Vitamin C Veterinary ozone therapy reviews (limited evidence); Merck Vet Manual—dogs synthesize vitamin C (routine IV-C not standard).  

A viewer question prompts Chris and Sophie to look into scrambler therapy. A medical therapy for chronic pain with a silly name that sounds like it should be pseudoscience, but actually isn't. How is it different from Transcutaneous Electrical Nerve Stimulation (TENS)? How good is the evidence and how much of the benefit is actually a placebo response.   Become a supporter of our show today either on Patreon or through PayPal! Thank you! http://www.patreon.com/thebodyofevidence/ https://www.paypal.com/donate?hosted_button_id=9QZET78JZWCZE  Email us your questions at thebodyofevidence@gmail.com.  Editor:    Robyn Flynn Theme music: “Fall of the Ocean Queen“ by Joseph Hackl Rod of Asclepius designed by Kamil J. Przybos Chris' book, Does Coffee Cause Cancer?: https://ecwpress.com/products/does-coffee-cause-cancer Obviously, Chris is not your doctor (probably). This podcast is not medical advice for you; it is what we call information.  References: 1)    2016 review of scrambler therapy for chronic pain https://doi.org/10.1007/s00520-016-3177-3 2)    2018 update https://doi.org/10.1177/1534735419845143 Key studies: Sabato (2005) – 226 patients: 80% had >50% pain reduction Marineo (2011) – RCT: 91% pain reduction in Scrambler group vs. 28% in controls Ricci (2012) – 82 patients: Mean pain scores dropped from 6.2/10 prior to treatment to 1.6 just after completing 10 treatment days to 2.9, 2 weeks after finishing treatment. Compagnone (2015) – 201 patients: pain went from 7.41 to 1.6 Notaro (2015) – All patients had ≥50% pain reduction; relief lasted ~8 weeks; sleep improved Pachman (2014) – 37 patients: 53% average pain reduction; effect lasted 10 weeks One ‘no results' study:  Campbell (2013) – 14 patients, RCT with sham control; no improvement—but team lacked experience, which may have skewed results.

Les Toulonnais ont très bien réussi leur rentrée, en allant s'imposer à Montpellier lors de la première journée de Top 14 (27-17). Très déçus de leur élimination en demi-finales la saison dernière, ils veulent cette fois encore se placer en outsider. Feront-ils mieux cette saison ? Ce nouveau RCT est-il plus fort que l'an passé ? Débat dans «Crunch». Un podcast présenté par Léa Leostic, avec Jean-François Paturaud, Adrien Corée et Romain Bergogne. Enregistrement : Marie-Amélie Motte.Hébergé par Ausha. Visitez ausha.co/politique-de-confidentialite pour plus d'informations.

Routine vaginal examinations (VEs) are a standard component of intrapartum care, traditionally performed at regular intervals to monitor cervical dilation, effacement, and fetal station, which are indicators of labor progression. Yet, the American College of Obstetricians and Gynecologists states that there is insufficient evidence to recommend a specific frequency for cervical examinations during labor, and examinations should be performed as clinically indicated. Now, a recently published RCT form AJOG MFM is adding additional credence to that. Can we space out clinical exams in otherwise “low-risk” laboring women to 8 hours? Listen in for details. 1. AJOG MFM: (08/18/25) Routine Vaginal Examination Scheduled At 8 vs 4 Hours In Multiparous Women In Early Spontaneous Labour: A Randomised Controlled Trial https://www.sciencedirect.com/science/article/abs/pii/S25899333250016122. Nashreen CM, Hamdan M, Hong J, et al.Routine Vaginal Examination to Assess Labor Progress at 8 Compared to 4 h After Early Amniotomy Following Foley Balloon Ripening in the Labor Induction of Nulliparas: A Randomized Trial. Acta Obstetricia Et Gynecologica Scandinavica. 2024;103(12):2475-2484. doi:10.1111/aogs.14975.3. First and Second Stage Labor Management: ACOG Clinical Practice Guideline No. 8. Obstetrics and Gynecology. 2024;143(1):144-162. doi:10.1097/AOG.0000000000005447.4. Moncrieff G, Gyte GM, Dahlen HG, et al. Routine Vaginal Examinations Compared to Other Methods for Assessing Progress of Labour to Improve Outcomes for Women and Babies at Term. The Cochrane Database of Systematic Reviews. 2022;3:CD010088. doi:10.1002/14651858.CD010088.pub3.5. Gluck, O., et al. (2020). The correlation between the number of vaginal examinations during active labor and febrile morbidity, a retrospective cohort study. [BMC Pregnancy and Childbirth]6. Pan, WL., Chen, LL. & Gau, ML. Accuracy of non-invasive methods for assessing the progress of labor in the first stage: a systematic review and meta-analysis. BMC Pregnancy Childbirth 22, 608 (2022). https://doi.org/10.1186/s12884-022-04938-y

Welcome to Season 2 of the Orthobullets Podcast. Today's show is Podiums, where we feature expert speakers from live medical events. Today's episode will feature ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Dr. Todd Albert and is titled⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ "⁠RCT on A vs P for Myelopathy.⁠"Follow⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Orthobullets⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ on Social Media:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Facebook⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Instagram⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠LinkedIn⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

Send us a textIn this episode, I'm joined by Dr. Sabine Vesting, a pelvic health physiotherapist and researcher whose work explores how exercise impacts the pelvic floor and abdominal muscles postpartum. Her research dives into common symptoms like urinary incontinence, pelvic girdle pain, and vaginal heaviness, and how they affect daily life for new moms.Now based in Ottawa, Dr. Vesting leads cutting-edge studies at the Motor Function Measurement (MFM) Lab, including research on running-induced urinary incontinence, pelvic floor responses after a single run, and the use of intravaginal devices to reduce leakage in female runners. She's also writing a review on how to best measure intra-abdominal pressure during exercise.We talk about:-Does diastasis actually matter?-Coning and doming explained-Finding exercise you enjoy postpartum-Urinary incontinence and new solutions-Intravaginal devices to understand the pelvic floor in sport and runningTime Stamps1:00 Introduction6:05 work as a PhD10:40 does diastasis even matter?16:24 pelvic girdle pain after pregnancy 21:00 changes over the last 15 years28:58 being comfortable with activity postpartum34:21 looking at pain and causes40:18 getting better measurements 51:42 intra-abdominal pressure55:32 doing what works with patients58:28 rapid fire questionsCONNECT WITH CARRIEIG: https://www.instagram.com/carriepagliano/Website: https://carriepagliano.comCONNECT WITH SABINE:Website: https://mfmlab.caLinkedIn: https://www.linkedin.com/in/sabine-vesting-aa4317135/?originalSubdomain=se We are currently recruiting participants for our RCT, aimed at evaluating whether readily available intravaginal devices, such as off-the-shelf pessaries or tampons, can effectively reduce or eliminate urine leakage during running, enabling active women to remain physically engaged. The study offers a remote option and welcomes female runners from all of North America who experience urine leakage while running.https://mfmlab.ca/portfolio-items/running-induced-urinary-incontinence-rct/The Active Mom Podcast is A Real Moms' Guide to pregnancy, postpartum, perimenopause & beyond for active moms & the professionals who help them in their journey. This show has been a long time in the making! You can expect conversation with moms and professionals from all aspects of the industry. If you're like me, you don't have a lot of free time (heck, you're probably listening at 1.5x speed), so theses interviews will be quick hits to get your the pertinent information FAST! If you love what you hear, share the podcast with a friend and leave us a 5 ⭐⭐⭐⭐⭐ rating and review. It helps us become more visible in the search algorithm! (Helps us get seen by more moms that need to hear these stories!!!!)

In this episode of the AI in Education Podcast, Dan and Ray dive into the latest developments shaping the future of AI in learning environments - from vocational colleges to elite universities. All the links to items and research discussed are below! News Australia's Future Skills Organisation and Microsoft launched the FSO Skills Accelerator-AI partnership https://www.futureskillsorganisation.com.au/skills-accelerator-ai/ Microsoft Elevate https://blogs.microsoft.com/on-the-issues/2025/07/09/elevate  Google commits US$1bn for AI training at US universities https://www.innovationaus.com/google-commits-us1bn-for-ai-training-at-us-universities/  CAUDIT Top Ten 2025 https://www.caudit.edu.au/resources/2025-top-ten-report/  South Korea pulls plug on AI textbooks https://www.koreaherald.com/article/10546695  Consumer news reporting on AI in Education ABC https://www.abc.net.au/news/2025-08-13/artificial-intelligence-in-the-classroom-education/105638698 Channel 9 https://www.youtube.com/watch?v=ZGUygg-q0ok https://www.9news.com.au/national/artificial-intelligence-in-schools-productivity-commission-report-national-push-for-teachers-to-use-gen-ai/4e9016dd-5de0-48de-ab64-f637adfbed53 Productivity Commission report that highlights the use of AI in education, including to reduce teacher workload https://www.pc.gov.au/inquiries/current/adaptable-workforce/interim  New DFE AI guidance for schools https://www.gov.uk/government/publications/generative-artificial-intelligence-in-education/generative-artificial-intelligence-ai-in-education  Ofsted's findings on AI in Education https://www.gov.uk/government/publications/ai-in-schools-and-further-education-findings-from-early-adopters/the-biggest-risk-is-doing-nothing-insights-from-early-adopters-of-artificial-intelligence-in-schools-and-further-education-colleges  Research AI tutoring outperforms in-class active learning: an RCT introducing a novel research-based design in an authentic educational setting https://www.nature.com/articles/s41598-025-97652-6  AI tools used by English councils downplay women's health issues Original paper: https://bmcmedinformdecismak.biomedcentral.com/articles/10.1186/s12911-025-03118-0 News reporting: https://www.theguardian.com/technology/2025/aug/11/ai-tools-used-by-english-councils-downplay-womens-health-issues-study-finds 

The opening of a new private clinic spurs Chris and Sophie to ask whether Transcranial Magnetic Stimulation (TMS) is real medicine or pseudoscience. How does a magnetic field stimulate the brain and how is this different from electric convulsive therapy (ECT)? Also, a brief digression on One Flew Over the Cuckoo's Nest and other classic movies Sophie has never seen.   Become a supporter of our show today either on Patreon or through PayPal! Thank you! http://www.patreon.com/thebodyofevidence/ https://www.paypal.com/donate?hosted_button_id=9QZET78JZWCZE   Email us your questions at thebodyofevidence@gmail.com.   Editor:    Robyn Flynn Theme music: “Fall of the Ocean Queen“ by Joseph Hackl Rod of Asclepius designed by Kamil J. Przybos Chris' book, Does Coffee Cause Cancer?: https://ecwpress.com/products/does-coffee-cause-cancer   Obviously, Chris is not your doctor (probably). This podcast is not medical advice for you; it is what we call information. References: 1) A study on the efficacy of ECT  by Slade et al. http://jamanetwork.com/article.aspx?doi=10.1001/jamapsychiatry.2017.1378 2) The accompany editorial on modern ECT use: Modern Electroconvulsive Therapy Vastly Improved yet Greatly Underused https://jamanetwork.com/journals/jamapsychiatry/fullarticle/2633172 3) A study on the safety of ECT: Lancet Psychiatry study 2021 https://doi.org/10.1016/s2215-0366(21)00168-1 4) Consensus statement on the use of Transcranial Magnetic stimulation (TMS)  https://doi.org/10.4088/jcp.16cs10905 5) Network meta-analysis comparing different TMS modalities https://doi.org/10.1001/jamapsychiatry.2016.3644 6) The durability of response after TMS treatment: https://doi.org/10.1016/j.brs.2018.10.001 7) RCT comparing ECT and TMS and showing ECT is more effective:  https://pubmed.ncbi.nlm.nih.gov/17202547/ 8) The older cochrane review from 2002 suggesting little benefit: https://doi.org/10.1002/14651858.CD003493

Primary hyperparathyroidism is an underdiagnosed condition which leads to decreased bone mineral density, fracture, renal disease, among other symptoms that can decrease the quality of a patient's life. Moreover, once diagnosed, only a small fraction of patients with the diease end up being offered surgery. Whether it is because of misunderstood indications and benefits of surgery, non-localization of disease, or various other reasons, we thought it was worthwhile to review relevant literature. Hosts: Dr. Becky Sippel is an endowed professor of surgery at Division Chief of endocrine surgery at University of Wisconsin Madison and she is the most recent past president of the AAES.  She is an internationally recognized leader in the field of endocrine surgery. She has over 250 publications. She was the PI for a RCT which studies prophylactic central neck dissections which is a widely read and quoted study in endocrine surgery. Dr. Amanda Doubleday is a fellowship trained endocrine surgeon in private practice with an affiliation to UW Health. Her primary practice is with Waukesha Surgical Specialists in Waukesha WI.  Dr. Simon Holoubek is a fellowship trained endocrine surgeons affiliated with UW Health. He works for UW Health with privileges at UW Madison and UW Northern Illinois. His clinical interests are aggressive variants of thyroid cancer, parathyroid autofluorescence, and nerve monitoring.  Learning Objectives: 1 Understand the natural history of primary hyperparathyroidism and how the disease process can affect bone mineral density. 2 Learn about fracture risk associated with primary hyperparathyroidism. 3 Learn about decreased fracture risk in patients with primary hyperparathyroidism who have parathyroidectomy compared to those who are observed.  References: 1 Rubin MR, Bilezikian JP, McMahon DJ, Jacobs T, Shane E, Siris E, Udesky J, Silverberg SJ. The natural history of primary hyperparathyroidism with or without parathyroid surgery after 15 years. J Clin Endocrinol Metab. 2008 Sep;93(9):3462-70. doi: 10.1210/jc.2007-1215. Epub 2008 Jun 10. PMID: 18544625; PMCID: PMC2567863. https://pubmed.ncbi.nlm.nih.gov/18544625/ 2 Frey S, Gérard M, Guillot P, Wargny M, Bach-Ngohou K, Bigot-Corbel E, Renaud Moreau N, Caillard C, Mirallié E, Cariou B, Blanchard C. Parathyroidectomy Improves Bone Density in Women With Primary Hyperparathyroidism and Preoperative Osteopenia. J Clin Endocrinol Metab. 2024 May 17;109(6):1494-1504. doi: 10.1210/clinem/dgad718. PMID: 38152848. https://pubmed.ncbi.nlm.nih.gov/38152848/ 3 VanderWalde LH, Liu IL, Haigh PI. Effect of bone mineral density and parathyroidectomy on fracture risk in primary hyperparathyroidism. World J Surg. 2009 Mar;33(3):406-11. doi: 10.1007/s00268-008-9720-8. PMID: 18763015. https://pubmed.ncbi.nlm.nih.gov/18763015/ Please visit https://behindtheknife.org to access other high-yield surgical education podcasts, videos and more.   If you liked this episode, check out our recent episodes here: https://app.behindtheknife.org/listen

In this episode, we dive into a new pilot RCT exploring the addition of acetazolamide to furosemide in critically ill patients. We break down the study's methods, findings, and practical implications for fluid management in the ICU. Could this inexpensive, decades-old drug be the key to sustaining diuresis and preventing metabolic alkalosis? Tune in to find out.The Vasopressor & Inotrope HandbookAmazon: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://amzn.to/47qJZe1⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ (Affiliate Link)My Store: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://eddyjoemd.myshopify.com/products/the-vasopressor-inotrope-handbook⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ (Use "podcast" to save 10%)Citation: Maeda A, Brown A, Spano S, Chaba A, Phongphithakchai A, Hikasa Y, Pattamin N, Kitisin N, Nübel J, Nielsen B, Holmes J, Peck L, Young H, Eastwood G, Bellomo R, Neto AS. Furosemide with adjunctive acetazolamide vs furosemide only in critically ill patients: A pilot two-center randomized controlled trial. J Crit Care. 2025 Apr;86:155002. doi: 10.1016/j.jcrc.2024.155002. Epub 2024 Dec 16. PMID: 39689380.

In this podcast, Emma Sutherland is joined by psychophysiologist and Monash University researcher Dr Simone Peters - one of the world's leading experts in gut-directed hypnotherapy - to explore the rise of this behavioural therapy as a first-line treatment for IBS and other gut disorders. From her landmark randomised controlled trial (RCT) comparing hypnotherapy to the low fermentable, oligosaccharides, disaccharides, monosaccharides, and polyols (FODMAP) diet, to the development of the Nerva app, Simone presents compelling data on how this therapy works, with 75–80% of patients responding within six weeks. The recommendation to use gut-directed hypnotherapy for IBS now forms international treatment guidelines and this episode empowers practitioners to integrate mind-body approaches into clinical care for IBS and beyond. Covered in this episode: (01:04) Welcome Simone Peters (06:04) Hypnotherapy and gut conditions (08:04) Nerva app (13:36) Patient experience (17:35) IBS, males vs females (20:00) Drivers behind IBS (22:38) Psychogastroenterology (25:53) Research in gut-directed hypnotherapy (29:44) Dr Peters research (36:50) Who is it for? (39:26) Synergistic modalities (43:33) Future of gut-directed hypnotherapy (46:33) Final remarks Find today's transcript and show notes here: https://www.bioceuticals.com.au/education/podcasts/gut-directed-hypnotherapy Sign up for our monthly newsletter for the latest exclusive clinical tools, articles, and infographics: www.bioceuticals.com.au/signup/ DISCLAIMER: The information provided on fx Medicine by BioCeuticals is for educational and informational purposes only. The information provided is not, nor is it intended to be, a substitute for professional advice or care. Please seek the advice of a qualified health care professional in the event something you learn here raises questions or concerns regarding your health.

In this episode, we discuss the management of follicular lymphoma with Dr. Gilles Salles from Memorial Sloan Kettering Cancer Center. Here are the articles we discussed: 1. Relevance of Bone Marrow Biopsy in Follicular Lymphoma: https://pubmed.ncbi.nlm.nih.gov/35787017/2. TROG 99.03 (RCT of Systemic Therapy after Involved-Field Radiotherapy in Patients with Early-Stage Follicular Lymphoma): https://pubmed.ncbi.nlm.nih.gov/29975623/3. Long-term follow-up results of RCT comparing early rituximab monotherapy versus watchful waiting for advanced stage, asymptomatic, low tumor burden follicular lymphoma: https://pubmed.ncbi.nlm.nih.gov/40306831/4. RELEVANCE RCT: Lenalidomide plus Rituximab (R2) Versus Rituximab-Chemotherapy Followed by Rituximab Maintenance in Untreated Advanced Follicular Lymphoma: https://ascopubs.org/doi/10.1200/JCO.22.008435. GALLIUM RCT: Obinutuzumab Versus Rituximab Immunochemotherapy in Previously Untreated iNHL. https://pubmed.ncbi.nlm.nih.gov/37404773/https://pubmed.ncbi.nlm.nih.gov/28976863/6. Long-term follow-up of mosunetuzumab in relapsed/refractory FL: https://pubmed.ncbi.nlm.nih.gov/39447094/7. Epcoritamab in relapsed/refractory FL: https://pubmed.ncbi.nlm.nih.gov/38889737/8. Phase 3 inMIND RCT: Tafasitamab plus Lenalidomide and Rituximab for Relapsed or Refractory Follicular Lymphoma: https://ashpublications.org/blood/article/144/Supplement%202/LBA-1/5343199. Long term follow-up results from the Phase 3 PRIMA trial of rituximab maintenance in Follicular Lymphoma: https://ascopubs.org/doi/10.1200/JCO.19.01073

Are cancer rates going up or down? It seems like depending on where you look, you'll find different answers to the question. What's going on here — have some writers just got it completely wrong? Is it something to do with different types of cancer? Are we being confused by some kind of weird statistical artefact? All of the above? In this episode of The Studies Show, we do our very best to find out.The Studies Show is brought to you by Works in Progress magazine, the ultimate place online to read about new and underrated scientific and technological ideas that could make the world a better place. You can find a huge range of essays online, for free, at www.worksinprogress.co.Show notes* BBC Future article on early-onset cancer rates* BMJ Oncology article on global cancer incidence increasing by 79%* And its online supplementary information* July 2025 Economist article on how the world is winning the war on cancer* Saloni Dattani's 2025 article on the decline in global cancer rates* The GLOBOCAN data update from the IARC, 2002 and 2008* Our World in Data's graph on global cancer incidence over time* Their graph on smoking rates and lung cancer deaths* Their graph on stomach cancer death rates* New RCT on vaping and smoking cessation* A 90% drop in cervical cancer rates in England* The hepatitis B vaccine and a massive drop in liver cancer incidence in China* On H. pylorii, ulcers, and cancer* 2000 JAMA article questioning the utility of the 5-year survival rate statistic* 2014 PLOS ONE article that's more positive about the statistic* Tom's BuzzFeed News article on oncology* RCT of herceptin on breast cancer survival* Study on rates of colorectal cancer * And the same, in relation to BMICreditsThe Studies Show is produced by Julian Mayers at Yada Yada Productions. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.thestudiesshowpod.com/subscribe

We have covered Low Dose Aspirin (LDA) for pre-natal preeclampsia prevention MANY times before. But here's a good clinical question: Since preeclampsia can also pop-up in the first 6 weeks postpartum (pp), should we continue it in the immediate pp interval? There is a new publication, an RCT, in the AJOG that looked to answer this- and we will highlight that publication in this episode. PLUS, we will briefly summarize a separate publication from the American J Perinatology back in 2023 that also provided some clinical insights on this topic. Listen in for details.1. The association between postpartum aspirin use and NT-proBNP levels as a marker for maternal cardiac health: a randomized-controlled trial; July 2025 (AJOG): https://www.sciencedirect.com/science/article/pii/S00029378250047522. Christenson E, Stout MJ, Williams D, Verma AK, Davila-Roman VG, Lindley KJ. Prenatal Low-Dose Aspirin Use Associated with Reduced Incidence of Postpartum Hypertension among Women with Preeclampsia. Am J Perinatol. 2023 Mar;40(4):394-399. doi: 10.1055/s-0041-1728826. Epub 2021 May 3. PMID: 33940641.3. Mendoza M, Bonacina E, Garcia-Manau P, et al. Aspirin Discontinuation at 24 to 28 Weeks' Gestation in Pregnancies at High Risk of Preterm Preeclampsia: A Randomized Clinical Trial. JAMA. 2023;329(7):542–550. doi:10.1001/jama.2023.0691

Comments or feedback? Send us a text! Clinicians will often hear their clients express deeply felt needs, only to admit they've never shared them with their partner—usually due to fear of vulnerability or a defensive, adversarial dynamic that makes intimacy feel unsafe.  In today's episode, we are joined by Dr. James Cordova—Professor of Psychology at Clark University and creator of The Relationship Checkup—to discuss his new book, The Mindful Path to Intimacy. Dr. Cordova's book offers a powerful framework for understanding and transforming these relational patterns through the lens of mindfulness, compassion, and shared vulnerability.In our conversation, we explore:Why intimacy is often more terrifying than people expect—and why it's worth the riskHow mindfulness can serve as both a spiritual and relational practiceThe idea that attention is the most basic form of loveWhy many couples shift from infatuation to frustration, and what can be done about itHow interpersonal neurobiology helps us understand the push-pull of closeness and withdrawalWays to navigate shame, trauma histories, and fear of being fully seen in loveWhat distinguishes couples who flourish from those who simply coexist. Dr. James Cordova is a Professor of Psychology at Clark University and the creator of The Relationship Checkup, a pioneering, preventative intervention designed to assess and strengthen couples' relationships before problems escalate. He has led major research initiatives—including a $1.3M Department of Defense-funded RCT with Lt. Colonel Jeffrey Cigrang and a $1M NIH grant—demonstrating the model's effectiveness in both military and civilian populations. As founder and president of Arammu: The Relationship Checkup, Inc., Dr. Cordova is scaling this approach nationwide, training over 1,000 military counselors and integrating the model into primary care. He is the author of The Marriage Checkup, The Story of Mu, and The Mindful Path to Intimacy, the latter of which offers mindfulness-based tools for cultivating emotional and spiritual connection.To learn more about Dr. Cordova and his work, visit:http://www.arammu.comOr check out his latest book, The Mindful Path to Intimacy, from Guilford Press.

Comments or feedback? Send us a text! Clinicians will often hear their clients express deeply felt needs, only to admit they've never shared them with their partner—usually due to fear of vulnerability or a defensive, adversarial dynamic that makes intimacy feel unsafe.  In today's episode, we are joined by Dr. James Cordova—Professor of Psychology at Clark University and creator of The Relationship Checkup—to discuss his new book, The Mindful Path to Intimacy. Dr. Cordova's book offers a powerful framework for understanding and transforming these relational patterns through the lens of mindfulness, compassion, and shared vulnerability.In our conversation, we explore:Why intimacy is often more terrifying than people expect—and why it's worth the riskHow mindfulness can serve as both a spiritual and relational practiceThe idea that attention is the most basic form of loveWhy many couples shift from infatuation to frustration, and what can be done about itHow interpersonal neurobiology helps us understand the push-pull of closeness and withdrawalWays to navigate shame, trauma histories, and fear of being fully seen in loveWhat distinguishes couples who flourish from those who simply coexist. Dr. James Cordova is a Professor of Psychology at Clark University and the creator of The Relationship Checkup, a pioneering, preventative intervention designed to assess and strengthen couples' relationships before problems escalate. He has led major research initiatives—including a $1.3M Department of Defense-funded RCT with Lt. Colonel Jeffrey Cigrang and a $1M NIH grant—demonstrating the model's effectiveness in both military and civilian populations. As founder and president of Arammu: The Relationship Checkup, Inc., Dr. Cordova is scaling this approach nationwide, training over 1,000 military counselors and integrating the model into primary care. He is the author of The Marriage Checkup, The Story of Mu, and The Mindful Path to Intimacy, the latter of which offers mindfulness-based tools for cultivating emotional and spiritual connection.To learn more about Dr. Cordova and his work, visit:https://relationshipcheckup.comOr check out his latest book, The Mindful Path to Intimacy, from Guilford Press.

In this enlightening episode of The Birth Lounge podcast, HeHe dives into the world of skincare during pregnancy with nurse practitioner Claire O'Bryan, founder of The Skin Clique. They explore the surprising fact that most skincare ingredients are not regulated by the FDA and discuss what it truly means for a product to be 'clean'. They tackle common pregnancy skincare concerns such as melasma, acne, and the safety of popular ingredients like retinoids and salicylic acid. The episode also touches on the controversial topics of Botox, fillers, and the efficacy of supplements like collagen in skincare. Claire provides practical advice on crafting an effective, simple daily skincare routine and the importance of sunscreen, while addressing misconceptions about the need for sunscreen. Tune in to get evidence-based answers to your burning skincare questions and learn how to navigate the complexities of beauty products safely in pregnancy and beyond. 00:00 Introduction to Skincare Safety 02:00 Common Skincare Concerns During Pregnancy 03:50 Interview with Claire O'Bryan 04:51 Skincare Regimens and Fads 07:20 Pregnancy-Safe Skincare Ingredients 11:06 Acne Treatments During Pregnancy 15:33 Retinol Alternatives and Supplements 20:37 Daily Skincare Routine Essentials 25:16 Sunscreen Myths and Facts 34:51 Effective Sunscreen Reapplication 35:42 Blue Light Protection in Sunscreens 36:32 Impact of Screen Time on Skin 38:39 Understanding Botox and Fillers 44:32 Botox Safety During Pregnancy and Nursing 50:36 Microneedling and Skincare During Pregnancy 01:01:34 Preventing and Treating Stretch Marks 01:06:18 Conclusion and Final Thoughts   Guest Bio: Claire O'Bryan is a dynamic nurse practitioner and entrepreneur dedicated to empowering women and amplifying the voices of female healthcare leaders globally. Her mission extends beyond traditional medical aesthetics – she's reshaping how we think about healthcare delivery while paving the way for women in leadership. As the co-founder of Skin Clique, Claire continues to help revolutionize the medical aesthetics industry through a groundbreaking concierge model. Since launching Skin Clique in 2019, what began as a vision for more accessible skin health has grown into a nationwide network of 1,000 skilled providers across 43 states. This expansion reflects not just business success but a transformation in how people access professional treatments and skincare. It is the modern approach to skin health.   INSTAGRAM: Connect with HeHe on IG   Connect with Claire on IG   BIRTH EDUCATION: Join The Birth Lounge here for judgment-free childbirth education that prepares you for an informed birth and how to confidently navigate hospital policy to have a trauma-free labor experience: https://www.thebirthlounge.com/   Download The Birth Lounge App for birth & postpartum prep delivered straight to your phone: https://www.thebirthlounge.com/app-download-page   LINKS MENTIONED: www.claireobryan.com www.skinclique.com: Use code Claire10 for a discount!    Pregnancy safe skincare:  https://shopmy.us/collections/549485   Collagen meta analysis:  https://pmc.ncbi.nlm.nih.gov/articles/PMC10180699/?utm_source   ACOG  https://www.acog.org/womens-health/faqs/toxic-chemicals-steps-to-stay-safer-before-and-during-pregnancy   ACOG Skin Conditions https://www.acog.org/womens-health/faqs/skin-conditions-during-pregnancy   Retinol VS Bakuchiol in a double blind RCT  https://pubmed.ncbi.nlm.nih.gov/29947134/   Systematic Review of Retinol VS Bakuchiol  https://pubmed.ncbi.nlm.nih.gov/36176207/   Collagen  https://pmc.ncbi.nlm.nih.gov/articles/PMC10180699/  

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-440 Overview: Explore current and emerging treatments for myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), a debilitating condition with no known cause or cure. Learn how oxaloacetate may offer new hope for patients struggling with ME/CFS, and gain practical guidance to support informed, evidence-based conversations with your patients. Episode resource links: Cash A, Vernon SD, Rond C, Bateman L, et al. RESTORE ME: a RCT of oxaloacetate for improving fatigue in patients with myalgic encephalomyelitis/chronic fatigue syndrome. Front Neurol. 2024 Nov 27;15:1483876.  Cash A, Kaufman DL. Oxaloacetate Treatment For Mental And Physical Fatigue In Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and Long-COVID fatigue patients: a non-randomized controlled clinical trial. J Transl Med. 2022 Jun 28;20(1):295.  CDC ME/CFS Basics Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Guest: Alan M. Ehrlich, MD, FAAFP   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at FranklySpeaking@pri-med.com  

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-440 Overview: Explore current and emerging treatments for myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), a debilitating condition with no known cause or cure. Learn how oxaloacetate may offer new hope for patients struggling with ME/CFS, and gain practical guidance to support informed, evidence-based conversations with your patients. Episode resource links: Cash A, Vernon SD, Rond C, Bateman L, et al. RESTORE ME: a RCT of oxaloacetate for improving fatigue in patients with myalgic encephalomyelitis/chronic fatigue syndrome. Front Neurol. 2024 Nov 27;15:1483876.  Cash A, Kaufman DL. Oxaloacetate Treatment For Mental And Physical Fatigue In Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and Long-COVID fatigue patients: a non-randomized controlled clinical trial. J Transl Med. 2022 Jun 28;20(1):295.  CDC ME/CFS Basics Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Guest: Alan M. Ehrlich, MD, FAAFP   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at FranklySpeaking@pri-med.com  

Welcome back to Papers of the Month! Three more papers to both inform and challenge our practice across the spectrum of emergency care. First up we look at a systematic review and meta-analysis on noradrenaline vs adrenaline for our medical post-ROSC patients; what evidence exists out there and should we all be delivering noradrenaline as our first line treatment for those with shock? Next up a paper to really challenge the treatment algorithm for status epilepticus in paediatrics, with an RCT of midazolam and ketamine versus midazolam alone. There are some huge differences here in the form of termination rates and some great discussion to be had around the specifics of the paper and how that might translate into future practice. Finally we look at a paper assessing the impact of i.m. versus i.v. metoclopramide for migraines and acute severe headaches. The paper looks at the impact of length of stay within the Emergency Department and also the efficacy of the treatment. Once again we'd love to hear any thoughts or feedback either on the website or via X @TheResusRoom! Simon & Rob

Last time we spoke about the victory at Okinawa.. As American forces led by General Buckner advanced, they captured strategic key points, driving the Japanese into a desperate retreat. Despite overwhelming odds, the remaining Japanese defenders, embodying the samurai spirit, fought to the bitter end, hoping to gain time for their homeland's defenses. On June 21, faced with inevitable defeat, Generals Ushijima and Cho chose to commit seppuku in honor of their duty. Their tragic decision underscored the deep commitment to their cause, an adherence to the warrior code. By this point, countless Japanese soldiers surrendered, acknowledging the futility of their fight. As the month drew to a close, the Americans secured Okinawa, a hard-won victory shadowed by staggering casualties, more than 107,000 Japanese lives lost and significant American losses. This battle not only symbolized the relentless spirit of those who fought but also the tragic costs of war, forever etched in history as a vivid reminder of sacrifice and the haunting price of conflict. This episode is Liberation of Luzon Welcome to the Pacific War Podcast Week by Week, I am your dutiful host Craig Watson. But, before we start I want to also remind you this podcast is only made possible through the efforts of Kings and Generals over at Youtube. Perhaps you want to learn more about world war two? Kings and Generals have an assortment of episodes on world war two and much more  so go give them a look over on Youtube. So please subscribe to Kings and Generals over at Youtube and to continue helping us produce this content please check out www.patreon.com/kingsandgenerals. If you are still hungry for some more history related content, over on my channel, the Pacific War Channel you can find a few videos all the way from the Opium Wars of the 1800's until the end of the Pacific War in 1945.  For most, the battle of Okinawa basically ends the Pacific War, but the truth is the war was raging all over the place. The second most noticeable place would be Luzon, where the remnants of General Yamashit'as 14th Area Army were still resisting in the northern and eastern mountain ranges. Yet here too, the curtains were beginning to fall. As we last left off, it was mid-April 1945, and the fierce struggle for the liberation of Luzon was reaching a critical phase. General Eichelberger's 8th Army was actively engaged in offensives across the Visayas and Mindanao, while General Krueger's 6th Army focused its might on two primary sectors in Luzon. The stakes were high, the liberation of Luzon was crucial for securing Manila and restoring the Filipino government that had been disrupted by the war. In the northern sector, General Swift's 1st Corps was grappling with General Yamashita's formidable Shobu Group, who were entrenched in this mountainous terrain, making the fighting particularly arduous. Meanwhile, General Hall's 11th Corps was applying relentless pressure on the opposing Shimbu Group, led by General Yokoyama, in the vital areas east of Manila. Starting in the northern reaches of Luzon, we find General Clarkson's 33rd Division making tangible advances, having secured Route 11 up to Camp 3, as well as segments of the Galiano Road and the Tuba Trail. This area, known for its treacherous paths and thick jungle, posed significant challenges, but the troops pressed on. Northward, General Beightler's 37th Division was also on the move, with its 129th Regiment overcoming all enemy resistance along Route 9, reaching the critical town of Sablan by April 14. Not to be overlooked, Colonel Volckmann's guerrilla 121st Regiment had carved a path up Route 4 to the strategically important Bessang Pass, known for its rugged terrain that offers a natural defense. General Mullins' 25th Division was making notable progress towards Balete Pass, gaining crucial footholds on Crump Hill and Myoko Ridge. These positions were essential as they provided elevated vantage points over the surrounding valleys. On the western front, General Gill's 32nd Division had successfully secured the western Salacsac Pass but still faced stiff enemy positions in the eastern pass, where Japanese forces were well-prepared to defend. With the arrival of the bulk of the 37th Division in early April, Swift was poised to launch a dynamic two-division drive towards Baguio, a city nestled in the mountains that had become a strategic goal due to its position and resources. While Clarkson's units continued to engage in patrol actions in the Arboredo, Agno, and Ambayabang River valleys, there was limited progress in these areas. However, the 129th Regiment initiated a decisive attack on Sablan on April 11, successfully breaching Japanese defenses there by April 14. On that pivotal day, the 148th Regiment took charge of securing Route 9 through Calot, a vital corridor for advancing troops. Meanwhile, the 130th Regiment encountered fierce resistance as it pushed west of Asin along the Galiano Road, exemplifying the tenacity of Japanese forces determined to hold their ground. As the battle raged, General Yamashita was already strategizing to evacuate Baguio. By April 19, he made the decision to relocate to the Bambang front, leaving Major-General Utsunomiya Naokata, one of his trusted chiefs of staff, in command of the remaining forces.  Despite the growing pressure on Route 9, the Japanese command seemed out of touch by the second week of April 1945. They inaccurately assessed that the primary thrust of General Swift's 1st Corps would come along Route 11, allowing them to become complacent. This misplaced confidence led to a failure to redeploy troops to counter the increasing threat on their right flank. Instead of fortifying their defenses, they appeared to adopt an inexplicable, almost defeatist attitude, unusual for a military as disciplined as the Imperial Japanese Army. Compounding this lack of urgency was the intense effort from the 14th Area Army headquarters to evacuate civilians and supplies from Baguio, a city perched high in the Cordillera Central mountain range. This evacuation served as a clear signal that the situation was deteriorating, yet the Japanese command remained strangely passive. Yamashita's mindset regarding the unfolding crisis was evident when he made personal preparations to depart for the Bambang front on April 19. In a move echoing his earlier strategy for the Bambang area, he established an independent command for the Baguio front before his departure. Utsunomiya's responsibilities also included nominal command over the 19th Division, stationed north of Baguio, but his control was hampered by significant communication difficulties that plagued the Japanese forces. The first notable action Utsunomiya took was to relieve the 58th Independent Mixed Brigade from the 23rd Division's control, seeking to streamline command. Under Yamashita's directive to hold Baguio for as long as possible before retreating to a new defensive line, Utsunomiya issued an order for all troops along the existing Main Line of Resistance  "hold out to the last man." His tone betrayed the grim reality, coming across as almost ironic given the mounting pressures they faced. Meanwhile, General Sato's 58th Independent Mixed Brigade was frantically working to fortify defenses along Route 9, southeast of Calot. However, their efforts came too late to prevent the 148th Regiment from swiftly capturing Yagyagan on April 15, gaining a crucial foothold in the area. In response to this setback, Sato began sending reinforcements to the Irisan Gorge starting April 16, apparently under Utsunomiya's orders. This narrow, treacherous gorge, surrounded by steep cliffs, was seen as a pivotal point for a last-ditch defense. The Japanese troops managed to repel the initial assaults from the 148th Regiment on April 17, but as night fell, the Americans executed a series of enveloping maneuvers, ultimately securing Ridge A. The following morning, the 148th seized Ridge C; however, their frontal assaults against Ridge B were met with fierce resistance and ended in failure. On April 19, the tide began to turn. After a devastating air strike and concentrated artillery fire that neutralized most of the Japanese positions on Ridge F, the Americans finally captured Ridge B. Concurrently, other American units seized Hills D and E, effectively cutting off the Japanese retreat route. The relentless pressure continued, and the next day, Ridges F and G were subjected to intense attacks, which ultimately resulted in their capture. This relentless campaign forced the Japanese to withdraw to Ridge H, where they continued to regroup. After heavy bombardment, the Irisan Gorge was finally cleared on April 21, sending the surviving defenders scrambling in retreat. As these operations unfolded, the 130th Regiment was busy repositioning two battalions from the Galiano Road to the junction of the Yagyagan Trail along Route 9, poised to mount a coordinated attack on Asin from both the east and west. On April 22, they launched their offensive, catching the Japanese defenders by surprise and effectively dismantling their defenses. By the afternoon of April 23, the Galiano Road was opened for American forces, marking a significant advancement in their campaign. Concurrently, the 129th Regiment had taken over operations from the 148th Regiment and advanced against only scattered resistance, making significant progress as far southeast as the junction of the highway and the Galiano Road. However, their advance was ultimately halted due to concerns about a potential threat from the north. Seizing on this hesitation, General Utsunomiya decided to leave small delaying forces at Trinidad and Baguio, while initiating a general withdrawal to the north and northeast. With Utsunomiya's defensive lines weakened, American patrols were able to enter Baguio on April 24, met with surprisingly little resistance. By April 26, the 129th had effectively secured most of the city, facing only negligible opposition. Simultaneously, elements from the 123rd and 130th Regiments worked diligently to eliminate the remaining Japanese defenses on nearby Mount Calugong, along the Tuba Trail, and on Mount Mirador, ensuring the area was cleared for further American operations. Despite these American successes, Utsunomiya managed to escape with approximately 10,000 troops to the Baguio-Aritao supply road, a crucial evacuation route for Japanese forces. As the end of April approached and into the first days of May, the 37th Division continued to mop up the surrounding areas, further securing Trinidad. Meanwhile, the 33rd Division also pressed forward, capturing the Balinguay-Itogon-Pitican sector, enhancing their control over the region. Looking eastward, General Gill's demoralized 32nd Division was still engaged in fierce fighting through the Salacsac Pass, hampered in their advance along the Villa Verde Trail.  During the second week of April 1945, observers from the 6th Army headquarters reported alarming morale issues within the 32nd Division, echoing concerns that General Krueger had personally noted during previous visits to the front lines. The soldiers of the 126th and 128th Regiments were on the brink of complete mental and physical exhaustion. Front-line troops, many of whom had spent significant time overseas, were becoming overly cautious, possibly from the toll of constant combat. Conversations among the men frequently centered around one urgent topic: their rotation back to the United States. The once aggressive spirit characteristic of these combat troops was waning rapidly. With dwindling numbers and pervasive personnel issues, it was clear that the division would struggle to mount any spectacular gains in the coming days. If they couldn't quicken their pace along the critical Villa Verde Trail, reaching their objective, Santa Fe, by the targeted date of June 1 appeared increasingly unlikely. Delays would be catastrophic; they risked being trapped on the trail by the heavy rains of the impending wet season, which typically began in late May. Such circumstances would severely hinder their ability to withdraw and salvage their equipment from the treacherous mountainous terrain. Meanwhile, the Japanese forces retained key terrain advantages, allowing them to economically utilize their troops and reinforce their front lines almost at will. In stark contrast, the rugged landscape severely restricted the 32nd Division's maneuverability, forcing them to repeatedly launch costly frontal assaults with their diminishing strength. While terrain and weather conditions presented significant challenges, the growing personnel crisis loomed as a critical factor likely to further limit the division's progress in the days ahead. Compounding their challenges, General Iwanaka's reconstituted 2nd Tank Division had suffered heavy casualties, leaving General Konuma unable to provide further reinforcements. On April 17, the rested 127th Regiment finally began its move to relieve the beleaguered 128th Regiment at the western pass, launching operations to clear the last remnants of Japanese forces from the Hill 506-507 area. Although Hill 506B fell rapidly on April 19, and Hill 507C was captured three days later, American forces struggled to completely clear Hill 507D until May 2, underscoring the tenacity of the Japanese defenders. Despite the challenges, enough ground had been cleared by April 26 for the 2nd Battalion to initiate a drive east along and south of the Villa Verde Trail, aiming for the strategically important Hill 508. The Japanese forces, sensing this new threat, responded with fierce counterattacks from both the east and north, managing to delay the American capture of Hill 508 until April 29. The intense fighting illustrated the importance of this elevation, which offered vital visibility over the surrounding landscapes. In the days that followed, the 2nd Battalion expanded its control over Hill 508, establishing a defensive block on the Villa Verde Trail to the north while successfully repelling a series of heavy Japanese counterattacks. Meanwhile, the 3rd Battalion made significant strides by attacking and capturing Hill 509, further consolidating American positions in the area. Simultaneously, the 2nd Battalion of the 126th Regiment launched an offensive south from Hill 511, seizing Hill 515 on April 24. They advanced into the area north of Hill 508 while the 1st Battalion navigated through the rugged terrain of Hills 513 and 514, pressing southward to Hill 516. Their advance culminated in the capture of the crest of Hill 525, where they established a critical block on the Villa Verde Trail. However, the cost of these advances was significant. Due to the heavy losses incurred during these operations, the barely rested 128th Regiment began the process of relieving the exhausted 126th on May 3. Shortly after, the 128th's 2nd Battalion launched an assault southeast, successfully capturing Hill 526 on May 7, while some elements initiated a drive towards Hill 527. To the further east, General Mullins' 25th Division was persistently pushing its Santa Fe offensive against stubborn Japanese resistance. In a stroke of fortune, a successful aerial reconnaissance mission revealed that ground located just 1,000 yards west of their position might offer a more favorable route of advance to Balete Ridge, providing a welcome alternative to the challenging Myoko mass itself. On April 22, a reconnaissance force from the 27th Regiment successfully moved undetected to the southern slope of Balete Ridge, positioning themselves for a critical advance. The following day, the rest of the 2nd Battalion began to push toward Lone Tree Hill, while other units continued to exert pressure on the entrenched Japanese defenses at Myoko. Moving forward with enthusiasm and encountering negligible resistance, the Americans reached Lone Tree Hill on April 25, effectively bypassing the main concentrations of enemy forces. By April 27, the 2nd Battalion had advanced an impressive half mile beyond Lone Tree Hill, with its forward elements only three-quarters of a mile from Balete Pass. However, they were compelled to halt their advance due to the potential threat of an enemy counterattack looming on the horizon. Meanwhile, on April 23, the 35th Regiment began its ascent up Kapintalan Ridge, steadily making progress despite the challenging terrain. By April 27, their leading troops had reached a prominent knob located midway between Route 5 and Lone Tree Hill. The 161st Regiment was also making strides, continuing its attack northward towards Kembu Ridge, where they successfully secured Hill 4625 and the entirety of Highley Ridge by April 28. On that same day, the 27th Regiment began reinforcing their positions on Lone Tree Hill, while elements of the 2nd Battalion initiated a southwest push along Kapintalan Ridge to support the 35th Regiment advancing up Route 5. However, they encountered a formidable strongpoint and were only able to gain 350 yards of new ground northeast from the knob. Simultaneously, elements of the 27th Regiment advanced a modest 500 yards southwest by May 4, indicating the ongoing struggle. That morning, the 1st Battalion of the 161st Regiment seized the southeastern nose of Kembu Ridge, securing a valuable tactical position. At the same time, the 2nd Battalion pushed troops onto the ridge, extending their reach half a mile to the northwest, further consolidating American control in the area. As a breakthrough appeared imminent, General Krueger began dispatching Beightler's 37th Division to the Bambang front on May 2, with all elements of the division departing the Baguio area just three days later. With these reinforcements securing his rear and taking control of the Myoko massif, General Mullins ordered the 27th and 161st Regiments to concentrate their forces for a coordinated attack aimed at enveloping Balete Pass from both the east and west. On May 5, the 161st swiftly broke through Kembu Ridge and advanced to Haruna Ridge, while the 27th Regiment pushed west-northwest along Wolfhound Ridge. However, they faced fierce resistance, gaining only 350 yards against tenacious Japanese defenders. On May 8, Company I successfully launched a southwest offensive from their stronghold along a bare-crested ridge, while Company A deployed on Kenbu Ridge and began ascending the final sections of the Digdig River gorge. The following day, these two companies finally made contact with each other and linked up with the 161st on Haruna Ridge. By May 10, Wolfhound Ridge was secured, coinciding with elements of the 35th Regiment completing the clearance of Route 5 from Kapintalan to the pass. In the meantime, the 35th Regiment, along with units from the 27th, continued their assault on Kapintalan Ridge, which was ultimately secured by May 13. Meanwhile, the 148th Regiment renewed its attacks on Myoko Ridge, where Japanese resistance began to collapse by May 11. With these gains, Balete Pass was now secure. The Americans had incurred 565 men killed and 1,745 wounded during the drive, while General Okamoto's 10th Division experienced catastrophic losses, with nearly 7,000 men killed and a complete breakdown of their control and communications. Reflecting on the situation in Salacsac, by May 8, the Japanese position was deteriorating rapidly. In response, General Iwanaka made the critical decision to dispatch troops aimed at cutting the supply line to the 2nd Battalion of the 128th Regiment, with the intention of safeguarding his main stronghold at Mount Imugan. On that day, the 1st Battalion of the 128th Regiment began to push eastward, facing strong resistance, while elements of the 2nd Battalion moved west from Hill 526, struggling to make any significant progress. By May 10, Japanese forces successfully severed the track between Hills 525 and 516, forcing much of the 128th and one battalion of the 127th Regiment to allocate considerable resources to eliminate the Japanese pocket that had formed in that area. Meanwhile, the 33rd Division was left disheartened as it found itself assigned a holding mission to secure the Baguio-Bauang-San Fernando area. Their operations were limited to minor local gains and long-range reconnaissance, which did little to impact the overall situation.  During May 1945, the only significant action undertaken by the 33rd Division took place along a trail connecting Santa Rosa in the Ambayabang Valley to Tebbo, located on the Agno River five miles south of Pitican. The division focused its efforts on clearing Japanese forces from the high ground situated between the main trail and the upper reaches of the Ambayabang Valley. On May 9, a battalion of the 130th Regiment advanced south from Baguio via Pitican and reached Tebbo, only to find the barrio abandoned. Meanwhile, on May 5, the 136th Regiment began its advance up the Ambayabang Valley. Approximately three miles south of Tebbo, they became embroiled in a ten-day battle, resulting in the deaths of a few hundred Japanese troops. However, these enemy forces posed little threat to the 33rd Division, their primary mission being to block American attacks toward the Baguio-Aritao supply road from the south. As the rainy season approached, 1st Corps and the 33rd Division had long since abandoned plans to use the valley as a route of advance against the Japanese supply lines. Consequently, the 136th Regiment relinquished the terrain it had gained along the valley and the trail to Tebbo almost immediately after capturing it. By May 15, all troops of the 33rd Division began their withdrawal, a challenging task compounded by heavy rains that had transformed the Pitican-Tebbo trail and the trails in the Ambayabang Valley into quagmires. The final destruction of the Japanese blocking force in the valley had little impact on the strategic plans or dispositions of 1st Corps or the Shobu Group, as the Japanese quickly replenished their outposts. By the end of May, the 33rd Division was left executing reconnaissance missions without significant enemy contact or major advances. The division remained in a state of restless anticipation, awaiting developments on the Bontoc and Bambang fronts before the 6th Army would authorize a new drive deeper into the rugged mountains of northern Luzon. Turning to the north, the guerrilla 121st Regiment achieved a significant victory on April 21 by overrunning the last Japanese positions on Lamagan Ridge. About a week later, they completed their occupation of Lower Cadsu. However, during the first part of May, the 121st Regiment faced formidable challenges as they advanced over steep terrain against increasingly fortified Japanese defenses, bolstered by reinforcements from General Ozaki's 19th Division. In the south, Hall's 11th Corps made good progress throughout mid-April, successfully pushing General Yokoyama's 41st Army, previously known as the Shimbu Group, further east from Manila. Concurrently, General Hurdis' 6th Division continued its offensive against the Kobayashi Detachment at Wawa Dam, achieving a notable success by securing the crest of Mount Mataba on April 17, marking a significant tactical gain in the ongoing battle. Despite General Hurdis' hopes to swiftly advance against Mount Pacawagan and Wawa Dam, persistent personnel issues forced him to halt any offensive actions until the 145th Regiment could relieve the 20th Regiment in the Montalban area. The 145th eventually began its assault on Pacawagan on April 21. However, even with effective supporting fire that destroyed much of the enemy's defenses, American forces struggled to secure a foothold on the mountain until the end of the month. Meanwhile, the 1st and 63rd Regiments continued to hold their occupied ground until they were relieved late in April by the 151st and 152nd Regiments of General Chase's 38th Division, which then officially assumed control of the offensive operations. In the southern part of Manila, significant water supply problems prompted General Hall to redeploy General Wing's 43rd Division northward in preparation for an offensive against Ipo Dam.  By mid-April 1945, an acute water shortage had developed within the city of Manila. General MacArthur informed General Krueger about the dire situation, noting that south of the Pasig River, Manila had access to no water sources except for that supplied by Army tank trucks and shallow, often contaminated wells. This shortage significantly hampered sewage disposal throughout the city, as water pressure from the overtaxed Novaliches Reservoir, the only reliable source was insufficient to carry off waste. As a result, flush toilets were frequently clogged, forcing many citizens to resort to using gutters and esteros for defecation. Restaurants and nightclubs, which were heavily frequented by off-duty American troops, struggled to maintain even minimum sanitary standards. The situation was exacerbated by a steady influx of military units and civilians into the metropolitan area, raising concerns about the imminent threat of severe epidemics breaking out in the city. On April 19, MacArthur suggested to Krueger that the 6th Army could resolve Manila's water supply crisis by seizing "the reservoir in the Montalban area." He inquired how soon the installation could be captured. This query puzzled Krueger, who was aware that the only true reservoirs linked to the Manila water system were located west of the Marikina River and had been under American control since February. Furthermore, Krueger understood that Wawa Dam, the nearest water supply installation to Montalban, was no longer connected to the metropolitan system. He subsequently asked MacArthur if by "reservoir in the Montalban area," he meant Ipo Dam, the only major water installation still in Japanese hands. Krueger's question seemingly led to further examination of Manila's water system at General Headquarters, Southwest Pacific Area (GHQ SWPA). On April 22, MacArthur radioed back to Krueger, confirming that Ipo Dam was indeed the preferred objective. He emphasized that capturing the Ipo installation would effectively solve Manila's water supply problems. Upon receiving this directive, Krueger ordered the 11th Corps to launch a drive on Ipo Dam as soon as possible. This shift in forces meant the 112th Cavalry Regiment had to move south to take over the vacated positions. General Wing conducted a reconnaissance-in-force that revealed the Kawashima Force's defenses south of Route 52 were considerably weaker than those around the main highway. In light of this intelligence, the plan for assault was set into motion. On the night of May 6, the 103rd Regiment was ordered to advance towards Mount Katitinga and prepare to attack the dam. Supporting this effort, the 172nd Regiment would strike across a two-mile-wide front to the left of the 103rd towards the dam, while the 169th Regiment was tasked with demonstrating along Route 52 to pin down Japanese forces in the Bigti region. Additionally, Marking's Fil-American Yay Regiment at Norzagaray was to make a feint drive eastward north of the Angat River, targeting Mount Kabuyao. During the first three days of May, General Chase conducted probing attacks in preparation for a concerted offensive aimed at Wawa Dam, which was set to begin on May 4. Simultaneously, General Yokoyama observed what he believed to be a slowdown in enemy progress, leading him to conclude that American forces must be redeploying northward or evacuating from Luzon entirely. This prompted him to prepare a limited counteroffensive, consisting of a series of harassing and delaying actions designed to pin down enemy forces on this front. Consequently, Yokoyama was not anticipating a major offensive on May 4. However, on that day, the 145th Regiment managed to gain up to 1,000 yards along the northern and northeastern slopes of Pacawagan, while the 152nd Regiment advanced approximately 500 yards northward along Woodpecker Ridge. Although these territorial gains were not monumental, Yokoyama became increasingly concerned about the strength of the American attacks and made the urgent decision to launch his counteroffensive. As Japanese forces hurried to reposition for their counterattacks, the 145th Regiment struck eastward, successfully seizing the rocky summit of Mount Binicayan. Meanwhile, the 152nd continued its efforts along Woodpecker Ridge. This coordinated assault completely surprised General Kobayashi's troops, rendering their planned counterattack impossible as they were forced to shift their focus to defending their critical positions. In the southern sector, General Kawashima dispatched one battalion toward Montalban; however, the heavy air assaults that preceded Wing's offensive made it impossible for the Japanese unit to organize effectively for their attack. Adding to the Japanese troubles, the remnants of the Noguchi Force were unable to provide any significant reinforcements. Despite the surprise and disarray among the Japanese defenders, they could not prevent the 145th from capturing the crest of Binicayan on May 9. The troops stationed on Woodpecker Ridge experienced some success by halting the advance of the 152nd and initiated a week of increasingly aggressive dawn and dusk raids starting on May 14. Recognizing the futility of the ongoing conflict, which had resulted in over 1,300 Japanese casualties, General Yokoyama ordered an immediate withdrawal of all units involved on May 15. However, these orders would not reach the front lines until a week later. In the meantime, capitalizing on the element of surprise achieved during the night attack on May 6, General Wing launched an offensive that made excellent progress. The 103rd Regiment rapidly gained control of the western slopes of Katitinga and advanced swiftly along the ridgeline toward Hill 1000. Meanwhile, the 172nd Regiment reached the foot of a rocky ridge two miles southeast of Bigti, and the Marking Regiment encountered no resistance as it marched over seven miles eastward, ultimately halting just a mile and a half northwest of Kabuyao. The only significant resistance encountered occurred at Hill 535, where elements of a guerrilla unit were repelled by Japanese defenders. The unexpectedly weak Japanese opposition prompted the 43rd Division to sustain its offensive momentum without pause. By May 11, the 103rd had secured Hills 805 and 810, while the 172nd was probing Japanese defenses on Fork Ridge and advancing to the southwestern slopes of rocky Hill 815. The Marking Regiment had successfully overrun Kabuyao, though they were unable to capture Four-Corner Hill. At this point, Japanese resistance began to stiffen as American forces clashed with General Kawashima's main defenses. In response, Wing ordered the 169th Regiment to mount a limited attack on Osboy Ridge and directed the Marking guerrillas to launch a strong assault toward Ipo. Supported by artillery, Colonel Marcus Augustin succeeded in breaking through Four-Corner Hill on May 12, marking a critical turning point in the offensive. Unaware of Kawashima's precarious situation, Yokoyama directed the Kawashima Force to initiate a new counterattack against the left and left rear of the 38th Division, deeming the situation for the Kobayashi Force to be more critical. As a result, Kawashima was compelled to divert one battalion for this unnecessary assault, which weakened the Japanese defenses. This strategic miscalculation enabled General Wing to make significant gains on May 13, with the 103rd Regiment capturing Hill 860, the 172nd clearing much of Hill 815, and the Marking guerrillas seizing the summit of Hill 803. The extent of these advances prompted Kawashima to ultimately disregard Yokoyama's orders and recall his assault battalion. This battalion promptly mounted a counterattack against the Americans in a futile attempt to regain lost ground, managing only to restrict the 103rd and 172nd Regiments to minor gains on May 14. Simultaneously, Colonel Augustin's patrols crossed the Angat River unopposed, discovering that the dam remained intact and the powerhouse on the south bank was largely undamaged. However, the patrol force, too weak to hold these installations, retreated before dawn to the crest of Hill 803, where the remainder of the regiment was occupied with mopping up remaining resistance. Looking further south, General Griswold's 14th Corps had already secured most of southern Luzon and had successfully landed General MacNider's 158th Regiment in the Bicol Peninsula. In response, the remnants of the Fuji Force and the depleted Kogure Detachment decided to evacuate the open Santa Maria Valley, opting to retreat to more defensible positions at the Kapatalin Sawmill. This allowed Griswold to move the 7th and 8th Cavalry Regiments into the valley, with the former beginning a drive along Route 455 on May 6. Following a heavy air and artillery bombardment, the cavalrymen launched their assault on the sawmill on May 9 and swiftly overran the enemy defenses by mid-afternoon. After a brief pause to reorganize, the 7th Cavalry advanced up Route 455, leaving their vehicles behind, and reached Lamon Bay by May 13. Meanwhile, on the Bicol Peninsula, progress had been agonizingly slow throughout late April. It wasn't until April 28 that the Cituinan Hills were fully secured, leading to the collapse of organized Japanese resistance in the region. Following this, the 158th Regiment began moving northwestward toward Iriga and San Agustin, rapidly overrunning the remaining weak enemy positions along Route 1. Progress continued to be painfully slow, and it was not until 28 April that organized Japanese resistance finally collapsed. The task of clearing the Cituinan Hills cost the 158th Infantry approximately 40 men killed and 235 wounded; the Japanese lost almost 700 men killed in the region. Although the 158th RCT did not know it, the reduction of the Cituinan Hills marked the end of large-scale organized resistance on the Bicol Peninsula, where no more than 1,400 Japanese remained alive as of the end of April. Simultaneously, the 5th Cavalry Regiment captured Calauag on April 14 and began a two-pronged advance toward San Agustin by the end of the month. On May 2, San Agustin was finally taken as elements of both regiments converged there. Guerrillas had informed XIV Corps, which acquired control of the 158th RCT on 22 April, that a Japanese force of some 2,500 men was dug in along the slopes of Mt. Isarog, an extinct volcano centering eight miles northeast of San Agustin. This report the 5th Cavalry and 158th Infantry proved false in a series of patrol actions between 2 and 15 May. The next day, the 16th, General MacNider radioed to General Griswold that the Bicol Peninsula was secure and that no signs of organized Japanese resistance remained. The two regiments continued patrolling for some weeks until, on 6 June, the 5th Cavalry returned to southern Luzon. The 158th RCT busied itself with the problem of reorganizing and equipping guerrilla forces and in mid-June turned over responsibility for further mopping up to the Filipinos. To that time the operations to clear the Bicol Peninsula had cost the USArmy units involved approximately 95 men killed and 475 wounded. The Japanese had lost over 2,800 killed and 565 captured, including 350 Formosan labor troops whom the Japanese Army had left to fend for themselves. I would like to take this time to remind you all that this podcast is only made possible through the efforts of Kings and Generals over at Youtube. Please go subscribe to Kings and Generals over at Youtube and to continue helping us produce this content please check out www.patreon.com/kingsandgenerals. If you are still hungry after that, give my personal channel a look over at The Pacific War Channel at Youtube, it would mean a lot to me. In June 1945, amidst the Pacific War, American forces sought to liberate Luzon from General Yamashita's entrenched troops. Under Generals Eichelberger and Krueger, the 8th Army faced fierce resistance in the mountains and vital routes. As Japanese defenders struggled, the Americans advanced strategically, leading to fierce battles across treacherous terrain.  The turning point came with the seizure of Baguio, crucial for the campaign.

At the end of April 2025, we released an episode summarizing the ERAS update for 2025. In that episode/update, we summarized the data on extended spectrum prophylactic antibiotics at cesarean section in patients living with obesity. The ERAS protocol recognized the value of oral cephalexin and metronidazole for 48 hours in patients with obesity who receive single agent Cephalosporin prophylaxis preop. Now, a new (RCT) publication soon to be released in the Green Journal, evaluates whether using dual agent pre-op prophylaxis (ancef and zithromax) together with post op oral cephalexin and metronidazole has benefit in reduction of SSI composite risk. Does this help? When is too much prophylactic antibiotics, just too much? Listen in for details.