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On the latest episode of the DC Comics News Podcast, the DCN crew discuss all the happenings in the world of DC, including an official release date for HBO Max, Wonder Woman 1984 getting an official rating, release date changes for The Batman, Shazam 2, and The Flash, and lots more news! So sit back, and enjoy! Brad Filicky: www.twitter.com/filickyb1 Kelly Gaines: www.twitter.com/KelGainesWrite Seth Singleton: www.twitter.com/1MoreSingleton Steve J Ray: www.twitter.com/el_steevo Be sure to subscribe on Apple Podcast, Spotify, Stitcher, or Google Play, and if you like what you hear, please give us a 5-star rating and review! Follow us on social media: Facebook: www.facebook.com/DCComicsNews Twitter: www.twitter.com/DCComicsNews Instagram: www.instagram.com/DCComicsNews Tumblr: www.tumblr.com/DCComicsNews

Alternate Reality - Episode #400 There’s a party going on right here, and it’s Jon and Charlie celebrating their 400th episode. We’ve got special music, we’ve got good friends, and there’s the sexy ladies over there dancing on the…. Well you can’t see that so there’s no point in getting into it. Suffice it to say that there’s a lot of fun going on here but Jon and Charlie don’t let that get in their way. They’ve got comics to review, and by Jiminy nothing’s going to stop them. Jon continues to be challenged by the Immortal Hulk, while Charlie walks us through Spider-Geddon. Several DC comics then make the list, Supergirl, Hawkman, and Detective Comics respectively, and Charlie finishes talking about an Image book (of all things) about an STD that improves your looks??? Yep, you heard me. Lastly Jon and Charlie get some love from a couple longtime listeners who sent in voicemails to help us celebrate the 400th episode. There’s too much fun for your tiny mind to process on this episode of Alternate Reality!!! Enjoy. Comics: The Immortal Hulk #7 Spider-Geddon #1 Supergirl #23 Hawkman #5 Detective Comics #990 Beauty #24 Contact us at: alternaterealitypodcast@gmail.com Support the show by becoming a member of our Patreon. Visit our Patreon Page at: https://www.patreon.com/AlternateReality Follow us on Twitter: Show: http://twitter.com/AR_Podcast Jon: http://twitter.com/jonloveless Charlie: http://twitter.com/Xonslaught The Alternate Reality Facebook page can be located at: https://www.facebook.com/pages/Alternate-Reality-Podcast/433051756767081 Alternate Reality is a proud member of the Comics Podcast Network Check out the Network at: http://www.comicspodcasts.com/

Suddenly it feels like last week’s episode was a 2-parter. More new Marvel ‘Fresh Start’ title announcements. Several DC announcements from Emerald City Comic Con, including 4 Neil Gaiman-adjacent books and 2 new non DCU Brian Michael Bendis books. Why we do not relish selling C2E2 tickets in-store. February sales numbers are in. March event round-up.

On today's Daytime Confidential podcast Luke Kerr, Jamey Giddens, Jillian Bowe, Melodie Aikels and Regan Cellura dish the latest daytime headlines and storylines, including: Sherri Shepherd and Jenna McCarthy are out at The View, leaving only Whoopi Goldberg behind. TMZ is reporting that Rosie O'Donnell has signed on to return to the gabfest, but is it time to cancel the long-running talk show? Quinn lost her mind on The Bold and the Beautiful and attacked Liam with a sword. Several DC members would be cheering if she tried killing Hope, but Jamey insists he needs a California blonde on soaps. Deacon is back, but does he need to shave his pornstache? Who could have guessed Days of Our Lives would be tell a better corporate takeover storyline than The Young and the Restless? Kate and Sami teaming up to take down Stefano and EJ is must see TV. The DC crew is enjoying Kassie DePaiva as Eve Donovan. Michelle Stafford looks like she's having more fun playing General Hospital's Nina Clay than she did during her last five years on The Young and the Restless. Nina needs out of Silas' orbit as quickly as possible. We can't wait for Nina vs. Ava to finally happen. Ava and Sonny continue to play cat and mouse. Rafe and Molly end up in a car chase and car crash. Does GH need to cast a special Drivers Ed teacher so Port Charles' citizens can learn how to drive safely? Rafe admits he ran Patrick's car off the road on purpose, but someone else made him do it. Burgess Jenkins took over the role of Billy Abbott on The Young and the Restless. Some among the DC gang don't mind him as Billy and others think he should have been cast as Adam Newman. Billy and Chelsea have sex. Devon is losing his mind over Hilary. Lily's rivalry with Hilary has brought the character alive.

Dendritic cells (DCs) are bone marrow-derived professional antigen-presenting cells that act as master regulators of acquired and innate immune responses. Here, we review the available information on their role in human renal inflammation. In the 1980s and early 1990s, major histocompatibility complex class II antigen-(HLA-DR) positive DCs were first described in normal human kidneys and in the interstitium of kidneys from patients with glomerulonephritis. Several DC subtypes were subsequently distinguished based on their expression of CD1c/BDCA-1, CD141/BDCA-3 and CD209/DC-SIGN (in combination with HLA-DR). These cells were almost exclusively found in the tubulointerstitium, with increased numbers seen during glomerulonephritis. It appears that the human renal tubulointerstitium harbors different DC types which allow the collection of both exogenous as well as endogenous antigens. Plasmacytoid DCs have a plasma cell-like morphology and were commonly found within nodular tubulointerstitial infiltrates. Follicular DCs are rarely seen, but show a predominant localization in organized infiltrates. CD207/langerin is a marker for Langerhans cells. Langerin-positive cells have been found in association with the collecting ducts and urothelium. A functional characterization of these subtypes has been hampered by the difficulty of obtaining samples for analysis. However, these studies are clearly required to define the role of DCs and DC subsets in the pathophysiology of renal disease. Copyright (C) 2011 S. Karger AG, Basel