In April of 2022 the American Association of Colleges of Osteopathic medicine or AACOM graciously invited the D.O. or Do Not podcast to attend their national meeting, “Educating Leaders” conference in Denver, Colorado. Our two producers, Lerone Cark, MS-II at the New York Institute of Technology College of Osteopathic Medicine and Brooke Pillegi, MS-II at the Alabama College of Osteopathic Medicine, as well as Ben Berg, our pre-medical student liaison, attended the conference to continue or mission of promoting awareness of osteopathic medicine by interviewing leaders in the field.We would like to thank Dr. Robert Cain, president of AACOM, Joseph Shapiro, director of media relations and Helene Cameron, Vice President of medical education services for having us at the conference and supporting the podcast. We had an amazing experience and would recommend the conference for any medical or pre-medical students interested in learning more about the inner workings of osteopathic medicine and osteopathic medical education.On todays episode we talk with Dr. Sami Nandyal, a recent medical school graduate from Ohio University at Heritage College of Osteopathic Medicine in Athens, Ohio. She had won Student Doctor of the Year this year at the AACOM conference and is currently getting ready to start her family medicine residency at the University of Cincinnati. Dr. Nandyal talks about her experiences in medical school and why she has such a strong passion for family medicine, her experience with board exams, and her involvement with her community. She also gives great information and advice for medical students and pre-medical students alike. We hope you enjoy this episode.
We're back to discuss a new crossover and a wild enthusiast oriented event. First Benjamin talks about the new 2022 Mazda CX-50, which looks rugged and tough in all the marketing, but as it turns out that marketing is doing all the heavy lifting. Is the CX-50 comparable to a Forester Wilderness? And how much does that matter? Then Sami comes back from merry old England and the Goodwood Festival of Speed, which he described as a celebration of all things performance and speed. He talks about the new race cars, the hill climb and bowing to Dukes, because he was raised that way. Listen, subscribe and don't forget to get in touch! The guys are always eager to hear from you.
HALIMA ALI SHUWA: An karrama ta da lambar yabon gama digirin digirgir a matsayin dalibar da ta yi wa sa'o'inta fintinkau a fanni binciken sojojin garkuwar jikin bil'adama. Bugu da kari kuma sai ga wani babban kamfanin hada magunguna a duniya ya bata aiki sakamakon fahimtar amfanin abin da ta kware a fannin binciken kwayar halitta. --- Send in a voice message: https://anchor.fm/madubinkabara/message Support this podcast: https://anchor.fm/madubinkabara/support
Have you watched anything good lately? Well Jordana, Aleen, and Sami have, and fill you in on all their latest TV and movie finds. And yes, Everything, Everywhere, All At Once is discussed. Then onto everything, everywhere celeb drama. First up is Chris Pratt's latest Men's Health interview, and they unpack all the tea—re: Hillsong church accusations, comments about his son, and his place among the many Hollywood Chrises. Then, they couldn't not debrief North West's extravagant camp bday party, but are surprised by the lack of Kim K's posts about it. Did Kim go to Staten Island once and finally become grounded? The show wraps up with a RHOBH recap, as Jordana, Aleen, and Sami discuss Diana's callous comments about the CA wildfires—yikes Diana, yikes—and a new Betches airline is born.
Dylan is joined by Betches founder Sami Sage for a much-needed unpacking of Bravo drama. They start by discussing the explosive LA Times article about Randall Emmett, and why this shouldn't really be a surprise to anyone. Then, they discuss this week's episode of RHUGT, where Dorinda is starting to unravel, and Tamra is showing why she's a top-tier Housewife. Later, they discuss Beverly Hills, where Diana's performance at Garcelle's birthday party falls flat.
Our heroines are...taking a break! Don't take it personal, we just have "Chautauqua" things to do (did we just start a new code word?) We'll be back soon, catch up on our old episodes! Salt and Burn This is a "Supernatural" rewatch podcast, hosted by Sami and Valerie ("our heroines"). Each week they break down one episode of their favorite show "Supernatural," going scene by scene, blood splatter by blood splatter, pop culture reference by...well, you get the idea. And in each episode they find something that reminds them of their real lives, usually making fun of themselves and stopping short of a "bitch/jerk" moment. Subscribe if this sounds like your jam, and if you enjoy please leave us a review! Follow us on social! We are @saltandburnthis on Insta, Twitter, TikTok, and Facebook. We'd love to see you there!
For this week's DST Thursday, Aleen is joined by the one and only, Sami Sage! Sami joins Aleen to promote Back For Seconds episodes and to give DST'ers a taste of what they're missing if they aren't a subscriber. The episode kicks off with Sami and Aleen recounting their girls' trip to LA and Sami then quizzes Aleen on all the celeb sightings they had while there. They share their Cali-related DSTWs, and then read the listener DSTW of the week, which comes from a woman who is proud of herself for finally going to therapy (*snaps for therapy*). Next, they dig into the Dear DST of the week, which asks for their advice on how to deal with friends who are obsessively dieting—and not in the healthiest way. Don't forget to subscribe to DST Back for Seconds for only $2.99 a month, where you'll get to hear Sami and Aleen have many more behind the scenes convos, plus get the regular episodes a day early without ads.
Are you not sure which nomad career would work for you? Are you looking for your purpose, but no idea how to find out what that is?In this part of my interview with Sami Reed Cleaver, she walks us through all the stepping stones she took to find out which career works for her. She has a very clear mission now, but that was not always the case.Fun fact: the full interview with Sami is the most listened episode on the podcast ever. Click here to listen: The Mindset Shift You Need To Become A Digital Nomad[Over the past months, I've interviewed a lot of nomads, and I've learned SO much from them. I wanted to highlight some of the key insights I got from all the interviews released so far.I decided to release a 10-15 min Short Story episode every Thursday, in addition to the full interviews which go live every Monday.]-Skippers are building coliving communities in East Africa starting in the adventure-rich beach town of Diani in Kenya. They would love your feedback on everything from room designs to activities and amenities. Head to their website www.liveskippers.com where you can help inspire the next nomad community!
Host, Lindsey Carter, reunites with dear friend, Sami Clarke, on this episode as the duo reminisce on the early days of their friendship, the process of establishing a personal brand and building upon that foundation, and the importance of connecting your mind, body, and soul with daily routines, practicing gratitude, and taking on new perspectives to give yourself grace. For 100% discount use the code formcommunity at checkout on www.joinform.co for a free three month subscription Produced by Dear Media
Hey, Dishers! We're coming in hot this week and talking about Sal and Lamon's departures, Big Beyond Salem news, and how Days did at the Emmy's. We're also jumping into the week that was in Salem and discussing Abigail's murder, Lani's shocking confession, Abe and Paulina tying the knot, Sami returning and more! #Days #DOOL
Hosts: Amanda, Sami, Boom! Lawyered's Imani Gandy Topics: Reacting to disturbing headlines from a weekend without Roe Unpacking – and rejecting – the discourse around who's to blame Imani Gandy, reproductive rights lawyer, editor at Rewire News Group and host of the Boom! Lawyered podcast, joins to break down the legal landscape of abortion today, what it could look like tomorrow, and why digital security should top your post-Roe to-do list.
Today's story is “A Pride at Pride” by https://twitter.com/2dwilddog?lang=en (Darius Davis), a black queer african wild dog author, who uses writing as a way to prime readers to experience new perspectives.You can follow him on twitter @2DWildDog and his Sofurry page at https://2dstories.sofurry.com/ ((2dstories)) for future writing projects. Going to Pride can be overwhelming for a first timer. But for Sami, this young lion has his own pride to show him the ropes. With his trans friends, Alondra and Wyatt, acting as the young lion's tour guide, Sami gains access to a new world which emphasizes sex positivity, queer liberation, and a strong since of community. Question is, will Sami definitively discover something new about himself? Or will doubt take control and diminish his potential for self-growth? Read by B.P. Rugger, the ineffable Moo Moon. thevoice.dog | https://www.thevoice.dog/apple (Apple podcasts) | https://www.thevoice.dog/spotify (Spotify) | https://www.thevoice.dog/google (Google Podcasts) If you have a story you think would be a good fit, you can https://www.sofurry.com/view/1669084 (check out the requirements), fill out the https://drive.google.com/drive/folders/1z81u5O2i8PWSfEpzaVhHeTjrp1kKP7TX?usp=sharing (submission template) and get in touch with us on https://twitter.com/voiceofdogpod (Twitter).
Chuck and Sami talk about the Kenny Chesney show in Nashville, what they've been up to lately, country music news and Chuck reads Talk to Chuck reviews. Shaun Silva joins the episode half way through to talk about his role on Kenny's tour. See omnystudio.com/listener for privacy information.
Geneza 2:18-22 18. Domnul Dumnezeu a zis: „Nu este bine ca omul să fie singur; am să-i fac un ajutor potrivit pentru el.”19. Domnul Dumnezeu a făcut din pământ toate fiarele câmpului şi toate păsările cerului; şi le-a adus la om, ca să vadă cum are să le numească; şi orice nume pe care-l dădea […]
The guys take two completely different paths this week on the Unnamed Automotive Podcast. First Sami goes the family friendly route with the 2022 Toyota Sienna. Available only as a hybrid, Sami starts off by describing a few of the vans shortcomings before diving into what makes this a smart entry in the world of three row vehicles. Then Benjamin takes a walk on the wild side with the 2022 Subaru Forester Wilderness, an all-new trim package that boasts several off road modifications, similar to last year's Outback Wilderness. He seems pretty impressed with the effort applied by Subaru but he eventually gets pulled into a conversation about who exactly this crossover is made for. Finally the duo discuss an interview on The Verge with Ola Källenius, the CEO of Mercedes-Benz where the concepts of legacy and marketing collide in predictably awkward fashion. Drop in, listen, subscribe and stay in touch! Thanks for listening to the Unnamed Automotive Podcast!
A group of Kurdish writers visited the Sami region of Sweden as part of the 'Belongings' project, which was prepared in collaboration with the Amed Literature Centre and the Sami House. - Komeke ji nîvîskarên Kurd, di çarçoveya projeya 'Belongings' ku bi hevkarîya Wêjegeha Amed û Mala Samîyan hate amadekirin, serdana welatê Swêd, Herêma Samîyan kirin. Zêdetir derbarê vê mijarê di raporta Hatice Kamer de heye.
Sami Udell is nothing short of amazing, talented, and wildly entertaining. Her and her team cook for some of the world's biggest entrepreneurs, athletes, musicians…oh my. Let's just say her and Luda = besties. In this ep we cover how healthy and hearty meals align with her belief that we should quite simply eat good food. Sami's love for organic and local hits home for us! Links:WholeSam Instagram
Join the Diva of DOOL as we discuss this past week's show and the return of the Daytime Emmys to primetime. Abe and Paulina decide to marry and celebrate the new holiday of Juneteenth. Theo and Olivia return for the wedding. Johnny offers to film the wedding for Chanel. Lani is having visions of TR. Abe and Paulina are married in a colorful ceremony, but Lani reveals her secret after they jump the broom. Julie has an idea to save Lani. Johnny and Ally agrue over Chanel. Sarah attacks Nicole. Ava wants answers from Gwen. Nicole and Eric share a moment and an awkward encounter with Roman and Kate. Kate got messy. EJ and Belle support Chad when he goes to tell the children about Abby. Jan names the baby Shawn Christian. Jan again manipulates Shawn and drives Belle back into EJ's arms. Sami returns to surprise Lucas who proposes marriage. Sami leaves to confront EJ about a divorce. Leo runs into Clyde and gives him the stolen jewelry. EJ is suspious of Clyde. Chloe and Brady have an encounter with Leo. Maggie invites Bonnie and Nancy to play cards. Victor is insulting to Nancy about Chloe. Victor is hilarious as usual. Bonnie and Victor find something to agree on. Spoilers and rumors plus a look at Beyond Salem. Results from the Daytime Emmys and Red Carpet fashion.
Tuning in live from sunny CA, Aleen, Jordana, and Sami are out west for the U Up? show in LA. They debrief the live event (surprise—they had a great time), and chat about dating today. Is it possible to meet someone in person anymore? Speaking of meeting people in person, they go through the roster of stars they've seen in LA. No Pete Davidson, but they drop some other big names. On the same thread of big names, they break down the latest celeb drama. Brace yourself, there's a lot to debrief: Julia Haart is becoming the Jewish Kris Jenner, Khloe Kardashian's new beau is a finance bro, Kendall Jenner's break up, Brad Pitt's new GQ cover, and of course, a chat about the new Real Housewives Ultimate Girls Trip. Say all that 10x fast.
Our heroines are joined by a third today, who has an exciting story to reveal....let's just say he's not afraid of no ghosts. Salt and Burn This is a "Supernatural" rewatch podcast, hosted by Sami and Valerie ("our heroines"). Each week they break down one episode of their favorite show "Supernatural," going scene by scene, blood splatter by blood splatter, pop culture reference by...well, you get the idea. And in each episode they find something that reminds them of their real lives, usually making fun of themselves and stopping short of a "bitch/jerk" moment. Subscribe if this sounds like your jam, and if you enjoy please leave us a review! Follow us on social! We are @saltandburnthis on Insta, Twitter, TikTok, and Facebook. We'd love to see you there!
A Special Interview with Impact Wrestling Superstar Moose Moose joined me as we discussed his Monster's Ball match with Sami Callihan at Slammiversary, If the feud with Sami is over, The one former Impact/TNA star he would like to face, Returning to Atlanta on July 1 and 2, If he has a partner in mind if he ever decides to challenge The Good Brothers for the Impact Wrestling Tag Team Titles, The hot dog incident at Slammiversary and much more!
Like the Radio Show? Click the [Repost] ↻ button so more people can hear it! Follow us on Soundcloud: @data-transmission Follow us on Soundcloud: @datatransmission Follow our House Music Spotify Playlist: goo.gl/dHX1Cr Want more house music, tech house, deep tech, minimal? Subscribe to our Youtube Channel - bit.ly/dtytube Listen to DT Radio: Website: bit.ly/DTSite1 Pop Up: bit.ly/DTRadioPopUp1 Follow Data Transmission: Instagram: goo.gl/6LqfCJ Spotify: goo.gl/p1gaWy YouTube: goo.gl/3JmFbF Facebook: goo.gl/ZAsYwY Twitter: goo.gl/o1ZF3P iTunes Podcast: goo.gl/TK1Xxu Spotify Podcast: spoti.fi/31KIS6s Mixcloud Podcast: bit.ly/30CzOk0
Priya (BUB) and Alex (A.C. Freazy) pop in for a kōrero i tēnei ata and give us a sneaky first spin of BUB's new single 'Bored'! Officially out tomorrow. Also, you can catch BUB playing with Hans Pucket at Whammy on the 1st of July. Whakarongo mai nei!
Si & Veronica are feeling numb for episode 219! Two big breakups with former Bachelorettes this week. First, Michelle and Nayte shared they will be going their separate ways… but will they be able to keep the house money they were gifted or does it go back to ABC like their ring will go back to Neil Lane. Then, Katie Thurston and John Hersey also shared very different IG story statements on them being split. In happier news, Tia and her fiance, Taylor Mock, are expecting a baby! Tayshia's ex, Zac Clark, came to her rescue when some haters were trying to troll her for bikini pics. Let our girl live!! Nick Viall confirmed what some cruise tracking sites already been knew… the Bachelorettes will be spending part of their season on a cruise ship. Will it give luxury or Suite Life: On Deck? (Bachelor talk ends at time marker 25m:42s) Drake tried his hand at a house music album in honor of Virgil Abloh… but Beyonce might've out done him with the release of her new single featuring Queen of Bounce, Big Freedia. It doesn't help that Drake featured cheating king, Tristan Thompson, in his newest video. HBO wants more Jon Snow and is in development for a spin-off around him. Denise Richards and Charlie Sheen are split on how they view their 18-year-old daughter Sami starting an OnlyFans. Vee went “Yikes!” and got an irreversible ick for Jack Harlow posting a TikTok of him whining a cringy new Drake lyric. Contextually cute no more! Join us for what is always a good time and leave us a rating and review for a shoutout! Follow us @thefuturebachelor on Instagram! Thanks to you all who have subscribed! -- For fun, great music updated weekly, follow FUTURE BACHELOR on Spotify! ***SLAPPER OF THE WEEK*** "Gotta Move On" by Diddy, Bryson Tiller -- Follow us on Instagram!
Happy Fathers Day to Nick Cannon and Nick Cannon ONLY! In this house (podcast) we celebrate only Nick Cannon on Fathers Day because everyone else is just BORING in comparison, right? Sami Sheen (Charlie & Denise's kid) joins OnlyFans, we're all FREAKING OUT about how Tove Lo's name is pronounced, Molly-Mae gets stuck in another airport and kicked out of a beach club in Dubai (WHY!), Cassie's husband Alex tells Diddy to "move on" (but, like, in a bad way) and we tackle BOTH Ruby/i Roses in a segment called: 'Rubies Rose'. Plus, so many stressful break ups! R.I.P. #Mozalez, #Grause, #NaKnox and congrats to Calvin Klein and his bf for steppin' out! The guy who inspired Ari from Entourage gets married and so does Aziz Ansari! To a forensic data scientist! I know! That's kinda crazy! We're also taking The Psychopath Test aka Jeff Lewis' 25 Things You Don't Know About Me! Call 619.WHO.THEM to leave questions, comments & concerns, and we may play your call on a future episode. Support us and get a ton of bonus content over on Patreon.com/WhoWeekly. Learn more about your ad choices. Visit podcastchoices.com/adchoices
Cass var nyss kränkt över att ingen raggar på henne. Men så hände det? Och hon kände sig attackerad minst sagt. Elsa är sne på att Sami aldrig tar intiativ till att fota henne! Det är väl ändå en pojkväns uppgift eller? Och så diskuterar vi stigmat kring att förlåta otrohet. Varför har folk så svartvitt tänk just kring det? See acast.com/privacy for privacy and opt-out information.
In this episode of Occupied Thoughts, FMEP's Sarah Anne Minkin speaks with Sameeha Hureini, an activist and university student from A-Twani village in Masafer Yatta in the South Hebron Hills. Sameeha is one of the founders of Youth of Sumud and, together with her brother Sami, was recognized with the 2021 Front Line Defenders Award for Human Rights Defenders at Risk. Original music by Jalal Yaquoub.
Hosts: Amanda, Sami, Emily Amick Topics: Emily Amick, the brain behind @EmilyInYourPhone and former counsel to Senator Chuck Schumer, joins to unpack the progress on gun safety legislation Why this moment – and these Republicans – were able to break the inertia on legislation with a compromise bill worth fighting for Why Congress doesn't need the NRA to fall prey to misogynistic tropes that could threaten closing the boyfriend loophole The reason Emily tells you to call your members of Congress every single day
This week, please join author Roderick Tung, editorialist William Stevenson, and Associate Editor Sami Viskin as they discuss the article "First-Line Catheter Ablation of Monomorphic Ventricular Tachycardia in Cardiomyopathy Concurrent with Defibrillator Implantation: The PAUSE-SCD Randomized Trial" and the editorial "Can Early Ablation of Ventricular Tachycardia Improve Survival?" Dr. Greg Hundley: Welcome listeners to this June 21st, 2022 issue of Circulation on the Run. And I'm Dr. Greg Hundley, associate editor and director of the Pauley Heart Center at VCU Health in Richmond, Virginia. Listeners, what a very interesting forum that we're going to have in this session today with Dr. Rod Tung, bringing us an article from first line catheter ablation of monomorphic ventricular tachycardia in cardiomyopathy with concurrent defibrillator implantation. Some results from the Pause sudden cardiac death randomized clinical trial. This article is really interesting because it is collecting data from multiple centers from multiple countries in Asia. But before we get to that article, why don't we grab a cup of coffee and go through some of the other articles in the issue? Well, the first is entitled cardiovascular magnetic resonance for rejection surveillance after cardiac transplantation. And it comes to us from Dr. Jim Pouliopoulos from the Victor Chang Cardiac Research Institute. In this study, CMR based multiparametric mapping was initially assessed in a prospective cross-sectional fashion to establish agreement between cardiovascular magnetic resonance and endomyocardially based measures of cardiac rejection and determine the CMR cutoff values between various cardiac rejection grades. Then after that, a prospective randomized noninferiority pilot study was undertaken in adult orthotopic heart transplant recipients who were randomized at four weeks post orthotopic heart transplant to either CMR or endomyocardially based rejection surveillance. And clinical endpoints were also assessed at 52 weeks. And so listeners, what did this investigative team find? Well, despite similarities in immunosuppression requirements, kidney function and mortality between the groups, the rates of hospitalization and the rates of infection were lower in the CMR group. On 15 occasions, patients that were randomized to the CMR arm underwent endomyocardial biopsy for clarification or logistic reasons, representing a 94% reduction in the requirement for endomyocardially based surveillance. And so listeners, a noninvasive CMR based surveillance strategy for evidence of rejection in the first year after orthotopic heart transplantation is feasible. And interesting, listeners, these results really suggest the possibility for further studies to confirm whether CMR and perhaps in combination with other modalities could be used to survey orthotopic heart transplant patients for acute rejection without necessarily having to undergo endomycardial biopsy. There's an excellent editorial by Dr. Jim Fang from the University of Utah who also reviewed this paper. Well, listeners, let's next turn to the world of preclinical science. And this paper comes to us from professor Simon Sedej from Medical University of Graz. It involves the insulin and insulin growth factor one or IGF-1 pathway. And that is known as a key regulator of cellular metabolism and aging. Now, although its inhibition promotes longevity across species, the effect of attenuated IGF-1 signaling on cardiac imaging really remains controversial. So what did the authors find? Well, they found that cardiomyocyte IGF-1R over expression in mice resulted in physiological hypertrophy and superior cardiac function in early life, but led to accelerated cardiac aging, heart failure and reduced lifespan in late life. Mechanistically, increased cardiomyocyte IGF-1R signaling accentuated cardiac dysfunction by reducing autophagy and mitochondrial oxidative capacity at old age, and therefore clinically pharmacologic inhibition of cardiac IGF-1R signaling in late life could suppress the age related deterioration of cardiac performance and perhaps increase lifespan. And therefore age should be considered as a major outcome determinant in future clinical trials, testing IGF-1R P13K inhibitors for cardiac benefits. Well listeners, what is our next study? And this study is somewhat related to our feature discussion, which we'll get to in a few minutes. It's from Dr. Paolo Della Bella from San Rafael Hospital, and it is a two phase prospective multicenter randomized clinical trial that was performed to evaluate the benefit of ablation after first implantable cardiovert defibrillator, or ICD shock. And patients with ischemic or nonischemic dilated cardiomyopathy and primary or secondary prevention indication for ICD were enrolled in an initial observational phase until first appropriate shock. And that was phase A of the study. Then afterwards, they were re-consented and patients were randomly assigned in a one-to-one fashion in the second phase or phase B to immediate ablation. That's within two months from shock delivery or continuation of standard therapy. And the primary endpoint of the study was a composite of death from any cause or hospitalization for worsening heart failure. And amiodarone intake was not allowed except for documented atrial tac-arrhythmias. So listeners, what were the results from this trial? Well, ventricular tachycardia ablation after first appropriate shock was associated with a reduced risk of the combined endpoint of death or worsening heart failure for hospitalization, lower mortality and fewer ICD shocks. And these findings therefore provide support for considering ventricular tachycardia ablation after the first ICD shock. Now this study and the feature which will be coming up in a few minutes is nicely reviewed in an editorial from Bill Stevenson at Vanderbilt University. Well listeners, what other articles are in this issue? Well, from the mail bag, we have a research letter from Professor Solomon entitled Health Status Trajectories Before and after hospitalization for Heart Failure. Also, there is a second research letter from Professor Eikelboom entitled Rivaroxaban 2.5 Milligrams Twice Daily Plus Aspirin Reduces Venous Thromboembolism in Patients with Chronic Atherosclerosis. And then next there's an ECG challenge from Professor Rosenfeld entitled Around and Around, a Wide Complex Tachycardia. Well listeners, what a great series of articles. And now we're going to get on and visit with Rod Tung, Sami Biskin and Bill Stevenson to evaluate first line catheter ablation of monomorphic ventricular tachycardia in cardiomyopathy, concurrent with defibrillator implantation. Well, listeners, welcome to this June 21st feature discussion. And we're very fortunate today to have with us Dr. Roderick Tung from the University of Arizona in Phoenix. We also have our own associate editor, Dr. Sami Viskin from Tel Aviv Medical Center in Tel Aviv, Israel, and Dr. Bill Stevenson from Vanderbilt University in Nashville, Tennessee. Welcome gentlemen. Well, Roderick, we're going to start with you. Rod, can you describe for us some of the background information that went into the construct of your study and what was the hypothesis that you wanted to address? Dr. Roderick Tung: Well, thank you, Greg, Pause is really the culmination of a lot of personal academic and cultural exchanges between many Asian centers and particularly in China. In terms of exchanges, where we would go across overseas, do a lot of different VT cases. And this all started in about 2013. And at that point in time, I was struck by a lot of differences that we were seeing, particularly whenever they wanted us to do a case, it tended to be a nonischemic etiology patient, and they always wanted to see some sort of epicardial procedure. And these are the ones that are enriched for epicardial substrates. As many listeners know, the ischemics tend to have more endocardially based scars. And that's why epicardial BT ablation is typically reserved for those that either have failed endocardial or those ARVC patients or non-ischemic cardiomyopathy. So that was the first thing, is there's a paucity of ischemic cardiomyopathy in Asia, which is still inexplicable. The second thing that was really interesting in my observations going to Asia was that the defibrillator penetration and adoption is not widespread like it is in America. And in a very Amero-centric view, we always think that, oh, well, everything else is a departure from a standard of care. Well, when you look at 1.4 billion people, that's a really significant population at risk for sudden death that's not being treated the same way that we typically see it in a lot of Western cultures. So I felt like it was a perfect fertile grounds for clinical exploration. And that's really where Pause was born, is to be able to look at the impact of catheter ablation and ICD therapies on the risk of sudden death. And that's really how the trial began. Dr. Greg Hundley: And what was the hypothesis, Rod, that you wanted to address? Dr. Roderick Tung: Well, when we started designing Pause in 2014, 2015, there had only been two prior trials that were published and that was Smashed VT in New England Journal. And then there was VTAC by Karlheinz Cook in Lancet. So really the hypothesis was to be able to assess whether preemptive or first line catheter ablation at the time of defibrillator implantation, which is not what we do in the US, we usually wait till there's therapies, if that decreases the composite endpoint of recurrent VT cardiovascular hospitalization mortality. Dr. Greg Hundley: Very nice. And so describe for us, Rod, your study population, and then the design that you use to address the hypothesis. Dr. Roderick Tung: So this was a randomized controlled trial, multicenter across 11 centers in China, Korea, Japan, Taiwan. These were really well respected and regarded academic centers. I do want to give a shout out to many of them, Kyoko Sojima, who trained with Bill Stevenson, wrote so many seminal papers in VT. In Japan, Akid Nogogami who really was charged with and responsible for opacity some of the mechanisms of particular VT, then there's Yao Yin in Beijing who's done great work in atrial fibrillation, cardiac neuroablation. Ming Long Chen, Chan Yang Jeng. So some really great names, and it was done over 11 centers, one to one randomization between control, which was just ICD, and the active arm was ICD with catheter ablation within 90 days of the ICD implantation. Dr. Greg Hundley: And how many patients, and then what were your study results? Dr. Roderick Tung: So we ended up with 121 patients that were randomized, 61 versus 60, 180 were eligible and screened. And what was really also different about this trial compared to others is that we involved a non-randomized registry. Those were patients that refused to be randomized, and most typically didn't want to have a defibrillator. And that's where the cultural differences of ICD acceptance are different. For two reasons. Number one, physicians actually don't truly believe a lot of the defibrillator data is relevant to non ischemics in Asia and the Asian population. So there's actually a little bit of an academic barrier of generalizing historical ICD data to Asia, which I observed with a lot of the physicians. And number two, patients sometimes don't want that technology in there, and they have different ideas of sudden death. So these patients were actually put into a registry and followed prospectively with catheter ablation alone without background ICD therapy. And that's very unique because the amount of data that has been prospectively followed for ablation sans ICD therapy is very few. So that was 47 in the registry. And there was 121 that was one to one randomized. Dr. Greg Hundley: And what did you find? Dr. Roderick Tung: Well, we found that those that underwent concomitant ablation with their ICD implantation that presented with monomorphic VT had a lower rate of the composite triple endpoint of VT recurrence, cardiovascular hospitalization, and death. This was largely driven by a nearly 20% absolute risk reduction in VT recurrence. There was a 4% absolute risk reduction in cardiovascular hospitalization, but this is not significant. And mortality rates were low. It was seven and 8% in those arms. So one of the things that we were hoping to get to was actually looking at mortality, but I think this is challenging with background ICD therapy there. And number two, it's challenging because mortality rates are lower in non-ischemic cardiomyopathy. And that's because they don't have the concomitant comorbidities of peripheral vascular disease, coronary artery disease, older age, cetera. So we actually had a pretty low rate of mortality, which we were hoping to get to, but that wasn't able to be assessed in this because of the low rates. Dr. Greg Hundley: Very nice. Well, now listeners, we're going to turn to our own associate editor, Dr. Sami Biskin. And Sami, many papers come across your desk. What attracted you to this particular study? Dr. Sami Viskin: Well, we need to better define what is the optimal timing for VT ablation in patients with the organic heart disease. As we have seen many patients that are referred too late for ablation, where they already have an arrhythmic storm and recurrent shocks. And on the other hand, we have seen studies like the Berlin Study from Cook that fail to show any benefit on endpoints like heart failure or mortality. So the study by Tung arrived shortly after the different study by Paolo Della Bella, the PARTITA study, that was also studying patients at an earlier stage. So in the Partita study, they were studying patients at the time of the first ICD shock. And then Rod came with this study where he studied patients at the time of ICD implantation. Now, usually authors ask to get an executive review of their article. In this occasion, we as the editors, we saw the opportunity and asked Rod to submit his paper as fast as possible and made the correction as soon as possible so we could get the two papers dealing with early VT ablation in the same issue with an invited editorial by Dr. Stevenson so we could put everything in context. Dr. Greg Hundley: Very nice. Well, Bill, Sami has set you up very nicely here. And as the editorialist, help us put these results from Rod into the context of what we know already today in this sphere of investigation pertaining to VT shocks, defibrillator implantation. Dr. William Stevenson: Yeah. So first I want to congratulate Rod on a very important study. It has been so difficult to conduct randomized trials of VT ablation and intervention, and to be able to bring this to fruition and internationally in Asia is really quite an accomplishment. We definitely need more information that guides us as to when VT ablation should be performed in people who have defibrillators and are having spontaneous episodes of VT. And we know that in patients with ischemic heart disease, with coronary artery disease, post infarct VTs, that catheter ablation can reduce the episodes of recurrent VT and reduce shocks from VT. And this is a very important quality of life issue for patients with defibrillators. But we haven't really had good data, certainly not randomized multicenter data in other patient populations. And we still are grappling with, does a reduction in VT episodes improve other outcome measures? Does it really improve quality of life? Does it reduce hospitalizations? Does it translate to a reduction in mortality? And so Rod's study, one of the strengths of it being in Asia is that there were a lot of patients who had non-ischemic causes of heart disease. And more than a third of patients had arrhythmogenic right ventricular cardiomyopathy, and his study makes it clear that those patients really benefit substantially with a reduction in VT episodes. And that overall, VT episodes are reduced in all three of the subgroups of different diseases, the ARVC and the ischemics and the non ischemics that were included in the trial. But I think it's worth digging in a little more to the non-ischemics, because they did not seem to receive the benefit that the arrhythmogenic right ventricular cardiomyopathy and the ischemic cardiomyopathy patients received. So that the efficacy was largely driven by the benefit in the ischemics and the ARVC patients. So one of the important considerations I think is when you're in your office with a patient who has a defibrillator and has had episodes of VT, and you're considering does this patient need a VT ablation? I think that if they've got ischemic cardiomyopathy, this data strongly supports that approach. If they've got arrhythmogenic right ventricular cardiomyopathy, again, ablation is very likely to reduce their episodes of VT/ for the non-ischemic group, which is about a third of the patient population that Rod studied, the data are less convincing in that group. And we know that's a harder group to achieve success with, with ablation. So we'll definitely want more data in that group. And I'm looking forward to some of the more detailed and sub-study sorts of analyses that I'm sure Rod is planning. Dr. Greg Hundley: Very nice, Bill. Well, listeners, and Bill you've teed it up nicely to really sort of circle back through each of you and ask, what is the next study to be performed in this space? So we'll start with Rod and then Sami, and then finish up with you, Bill. So Rod, what is the next study that you see needs to be performed really in follow up to yours? Dr. Roderick Tung: Well, we're thinking Pause too might be a nice just ARVC study alone, because again, inexplicably, there's a very high incidence of ARVC in Asia, and I was always taught that this was a disease from the Veneto region of Italy. And that might not be the case, or there's a lot of sarcoid mimicking of it as ARVC and undiagnosed. But we're thinking about a Pause too being an ARVC study, maybe without background I,CD therapy with background ICD therapy, this might provide justification for that. Because again, those in the registry did quite well, but that's because they were younger and had ARVC and normal LV function. So that might be a nice area to explore worldwide. And then lastly, just to put things in perspective for the Circ listeners, you need 8,400 patients in paradigm to show benefit mortality and heart failure hospitalization for an ARNI. Right? For IRNESTO. We're talking about 120 patient studies when we talk about VT ablation, with these very complex ablation trials. So I think we just need larger trials. And the hard thing for us as VT ablation centers is we often will get patients that have had recurrent VT after a failed procedure. So it's hard to come by these that are very early, but I think we need 500 patient studies, a thousand patient studies. And also for the listeners, it's very hard to show mortality reduction with a background ICD therapy. And that's the problem, is that ICD is so effective as an abortive treatment that it's very hard to show reduction and mortality. You'd have to show it in terms of heart failure. Dr. Greg Hundley: Very nice, Rod. And Sami, what would you like to add? Dr. Sami Viskin: Oh, obviously the last word on the optimal timing of VT ablation is not out there. And we need more studies to really define when is the appropriate time for the VT ablation. That's what we need. Dr. Greg Hundley: Very good. And Bill? Dr. William Stevenson: Yeah, I agree with Sami. And with rod, we need larger studies to assess the benefit, to really help guide our clinical decision making that can get at quality of life issues as well as the mortality and cardiovascular hospitalization issues in even more detail. But this is a wonderful first initial step into the ischemic, non-ischemic and ARVC populations. Dr. Greg Hundley: Very nice. Well listeners, we want to thank Dr. Rod Tung from university of Arizona, Phoenix, Dr. Sami Viskin from the Tel Aviv Medical Center in Tel Aviv, Israel, and Dr. Bill Stevenson from Vanderbilt University in Nashville, Tennessee, for bringing us this study that highlighting among patients, particularly with ARVC in an ischemic cardiomyopathy from Asia across multiple centers in different countries that early catheter ablation performed at the time of ICD implantation really reduced the composite primary outcome of VT recurrence, cardiovascular hospitalization, or death. And these findings were really nicely driven by a reduction in the ICD therapies. Well, on behalf of Carolyn and myself, I want to wish you a great week and we will catch you next week, on the run. This program is copyright of the American Heart Association, 2022. The opinions expressed by speakers in this podcast are their own, and not necessarily those of the editors or of the American Heart Association. For more, please visit ahajournals.org.
Alexis celebrated at the MN Zoo! What American food is hard to find overseas? Wendy Williams iconic purple chair and her wigs will be thrown away? Charlie Sheen backtracks his comment on daughter Sami's OnlyFans site.
Check out The Restart Roadmap: Rewire and Reset Your Career now! In this week's episode, Jason is joined by two of the founders of Betches Media, Sami Sage and Jordana Abraham, who along with their best friend Aleen Dreksler started a blog in a college apartment that ended up going viral back in 2011. Since then, Betches has gone on to become wildly successful with twelve unique brands, podcasts, best-selling books and the list goes on. Sami and Jordana reveal the secrets behind starting and running a successful company with friends and keeping it that way, staying true to your brand, and expanding into the canned cocktail market. How much money did each of them invest into the company initially? What do they look for when interviewing someone to join the Betches team? How did they make their first dollar as a company? Where can you find their new canned cocktails Faux Pas? Jordana and Sami answer all of that and more in another episode you can't afford to miss. Follow Trading Secrets Podcast on Instagram here. Zencastr promo code JASON for 30% off your first three months. Sponsors: LinkedIn.com/SECRETS to post your job for free! Shopify.com/secrets for a free 14-day trial Host: Jason Tartick Voice of Viewer: David Arduin Executive Producer: Evan Sahr Produced by Dear Media.
1 Kings 19:3-4a 3And when he saw that, he arose and ran for his life, and went to Beersheba, which belongs to Judah, and left his servant there.4But he himself went a day's journey into the wilderness, and came and sat down under a broom tree. And he prayed that he might die
Welcome to the "Oops! All bangers!" edition of the Unnamed Automotive Podcast, where Ben and Sami dive into two of the coolest cars around. First Sami talks about the eighth-generation Rolls-Royce Phantom Series II that he drove (and was driven in) through Nice and Monaco. He talks how the company spent five years developing new wheel designs, and put twinkling stars in the headlight enclosures before describing the various customized models he got to check out before discussing the ultra luxury market and its clientele in detail. Then Benjamin gets ample time to chat about the one of best cars on the market for automotive enthusiasts: the 2022 Mazdza MX-5 Miata. He tested the SOLD OUT Club model, describes what's important about that model, and decides whether it's worth buying above the base edition. Of course he also brings up the Japanese automaker's new direction in the automotive industry, and whether the Miata will ever be this good again. Thanks for listening, be sure to subscribe, and send us a review, or reach out to us on social media.
Hello again! Today we've got two very different spooky stories for you! Jack tells the crazy story of potentially how the Buffalo Trace Distillery got some of its ghosts, and Sami talks yet again about secret tunnels! Hope you all enjoy!
Hosts: Amanda, Sami, Monique Melton Topics: Amanda and Sami are joined by Monique Melton (@moetivate), anti-racism educator, to discuss what Black liberation means in 2022 Unpacking corporate missteps when it comes to honoring Juneteenth Why Monique doesn't use the word “allies” How to approach conversations about racial equality with those who balk at “politics”
Hot Topics: Married to Medicine returns 7/10. Kardashian's want $391k from Blac Chyna. Charlie Sheen and Denise Richards react to 18 year old daughter Sami joining OnlyFans. Britney Spears wedding updates and quits Instagram. We Cover: RHOA Marlo tried to cheer up Sheree and the ladies attend Sanya's cooking party. Kardashian's on Hulu Finale full Tristan cheating breakdown, Kim tries to shoot a Xmas card and they all shoot promos for the new show. RHOBH shopping and surfing splits the ladies up but the drama continues at a very intense dinner. RHODubai Chanel Ayan is a star and the ladies attend Lesa's fashion show.
Jordana starts today's ep by debriefing the U Up? Live show in the cleaner, smaller New York—AKA Boston. Jordana, Aleen, and Sami are all going to the LA show next week, which will be the first time Aleen's been to SoCal since her choker-wearing days. Obvi they can't mention LA without a convo on the Kardashians, and how Kim K broke the Marilyn Monroe dress (yikes). They then talk about another LA star Justin Bieber, and his very scary facial paralysis. Next is a discussion of J.Lo's new movie Halftime, before getting into the fat-shaming drama surrounding influencer Remi Bader. They wrap up with a chat about Britney Spears' wedding (and her ex-BF wedding crasher), before debriefing how Erika Jayne can't afford to pay $2 million in taxes. Have you seen her closet?
Are you ready to dive behind the curtain and unpack the latest high profile divorce cases in our Bonus Divorce & Beyond Headlines Round Up Monthly episode? Get a behind the scenes look at some celebrity splits, high profile break ups and the stories behind the headlines from the Voice You Can Trust. In this month's Headline Round-up Susan discusses: Case Update: Country Singer Sam Hunt and Wife Welcome New Baby Girl Just Weeks After She Withdrew Her Divorce Petition Actress Busy Phillips Talks About Her Separation and Divorce on Her Podcast Tom Schwartz and Katie Maloney move out of house amid divorce Charlie Sheen blames ex Denise Richards after daughter Sami joins OnlyFans Valerie Bertinelli's Estranged Husband Tom Vitale Asks for Spousal Support After Divorce Filing Susan also shares some of her personal thoughts on the Johnny Depp and Amber Heard Trial Listen in and you will never look at the Headlines and Divorce the same way again! Episodes Mentioned in this Round-Up: Beth Behrendt with a View From the Nest: https://bit.ly/nestingplan Domestic Violence Part One: Coercive Control: https://bit.ly/Domesticabusepartone Domestic Violence Part Two: Post-Separation Abuse: https://bit.ly/domesticabuseparttwo ***************************************** MEET OUR CREATOR AND HOST: SUSAN GUTHRIE®, ESQ., the creator and host of The Divorce and Beyond® Podcast, is nationally recognized as one of the top family law and divorce mediation attorneys in the country. Susan is a member of the Executive Council of the American Bar Association Section of Dispute Resolution and is the Founder of Divorce in a Better Way® which provides a curated selection of resources and information for those facing divorce and other life changes. Internationally renowned as one of the leading experts in online mediation, Susan created her Learn to Mediate Online® program and has trained more than 20,000 professionals in how to transition their practice online. Susan recently partnered with legal and mediation legend, Forrest "Woody" Mosten to create the Mosten Guthrie Academy which provides gold standard, fully online training for mediation and collaborative professionals at all stages of their career. ***************************************************************************** Remember to follow Susan Guthrie and THE DIVORCE AND BEYOND PODCAST on social media for updates and inside tips and information: Susan Guthrie on Facebook @susanguthrieesq Susan on Instagram @susanguthrieesq Susan on Twitter @guthrielaw ********** If you want to see the video version of the podcast episodes they are available on The Divorce & Beyond YouTube Channel! Make sure to LIKE and SUBSCRIBE so you don't miss a single episode! *********** Finally, we'd really appreciate it if you would give us a 5 Star Rating and tell us what you like about the show in a review - your feedback really matters to us! You can get in touch with Susan at email@example.com. Don't forget to visit the webpage www.divorceandbeyondpod.com and sign up for the free NEWSLETTER to receive a special welcome video from Susan and more!! ***************************************************************************** DISCLAIMER: THE COMMENTARY AND OPINIONS AVAILABLE ON THIS PODCAST ARE FOR INFORMATIONAL AND ENTERTAINMENT PURPOSES ONLY AND NOT FOR THE PURPOSE OF PROVIDING LEGAL ADVICE. YOU SHOULD CONTACT AN ATTORNEY IN YOUR STATE TO OBTAIN LEGAL ADVICE WITH RESPECT TO ANY PARTICULAR ISSUE OR PROBLEM
Honestly, who doesn't love this episode? Our heroines are only upset it isn't dropped on a Tuesday...and stay tuned as one of them is in for a missed surprise easter egg (hint: one scene is not as silly as it appears). Salt and Burn This is a "Supernatural" rewatch podcast, hosted by Sami and Valerie ("our heroines"). Each week they break down one episode of their favorite show "Supernatural," going scene by scene, blood splatter by blood splatter, pop culture reference by...well, you get the idea. And in each episode they find something that reminds them of their real lives, usually making fun of themselves and stopping short of a "bitch/jerk" moment. Subscribe if this sounds like your jam, and if you enjoy please leave us a review! Follow us on social! We are @saltandburnthis on Insta, Twitter, TikTok, and Facebook. We'd love to see you there!
There is a lot of confusion behind what ‘be a man' means. Sami Moa says his definition is someone who is fulfilled. Someone who has been able to generate wealth in their relationships, their business & their health while having unshakeable confidence in themselves. Sami is a relationship coach who specializes in helping men become a better version of themselves to attract the kind of partner they want. He has made it his mission to teach men how to do this and has taught seminars in over 75 cities around the world and transforming the lives of thousands of men. More from Sami Moa https://samimoa.com/ Ministry of Attraction Tribe https://www.facebook.com/groups/moaforum/ Sami Moa on Facebook https://www.facebook.com/moatraining --- Send in a voice message: https://anchor.fm/manlihood/message Support this podcast: https://anchor.fm/manlihood/support
Sami (@Believe_Sami) and Eric (@SamskiNYC) welcome Chris Torres (@TorresTakes) to discuss whether or not Sami is being replaced on the podcast and what to do about current breaking news, like injuries to Ozzie Albies and Liam Hendriks. Then they discuss the catcher waiver wire landscape and look ahead for which fringe starting hitters have good upcoming weekends. All music in this episode is made by Brooklyn hip-hop artist Dan Dillinger, whose new album can be found on Spotify Timestamps 4:00 - Trending News Breakdown Fernando Tatis Jr. not healing as the Padres want Ozzie Albies fractured foot. Which 2B can you add to replace him? Jon Berti, Cesar Hernandez, Matt Reynolds, Ezequial Duran, Cavan Biggio Liam Hendriks to the IL. How much FAAB for Graveman? Corey Knebel is out as closer. Would you add Dominguez over Graveman? Edward Cabrera to the IL. Yoan Moncada has a great day. Does it matter? Leody Tavares gets called up: Taveras, Jarren Duran, or Edward Olivares? Oneil Cruz is coming up. Is he? I mean, really, is he? 39:00 - Catcher Landscape: We get in on the talk about the current crop of streaming catchers Gabriel Moreno Christian Bethancourt Cal Raleigh Jose Trevino Omar Narvaez Carson Kelly Elias Diaz Brian Severen 48:30 - Fringe Starters with Good Weekend Schedules: Are they playable? Didi Gregorius Bryson Stott Alec Bohm Seth Brown Hunter Dozier Andrew Benintendi Nomar Mazara Jurickson Profar Jake Cronenworth Jorge Alfaro Ji-Man Choi Vidal Brujan Dylan Moore J.P Crawford? Orlando Arcia Adam Duvall Michael Chavis Marcell Ozuna --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app Support this podcast: https://anchor.fm/eric-samulski/support
On this edition of PTBNXT, Tim, Jenny, and Jake continue their tradition of new gimmick names, then discuss the 1/28/15 and 2/4/15 episodes of NXT TV. The gang break down a shocking title change, Bayley showing some backbone, their man Neville, WWE Immortals, tensions rising for the women's fatal four-way, Bull Dempsey losing again, Corbin's biggest spot yet, a fantastic contract signing between Sami and KO, Carmella continuing to impress, a banger between Itami and Finn, and much more! So set sail at Full Sail for some top tier analysis and complete nonsense because We Are PTB...NXT!
Charlie Sheen blames his ex-wife, Denise Richards, after their eldest daughter, Sam “Sami” Sheen, joined Only Fans. Kim Kardashian is in paradise with boyfriend Pete Davidson. Britney Spears' ex-husband Jason Alexander was hit with a felony and must stay away from her for the next three years. Don't forget to vote in today's poll on Twitter at @naughtynicerob or in our Facebook group. See omnystudio.com/listener for privacy information.
Hosts: Amanda, Sami, Kellie Leeson, candidate for NY State Assembly-District 73 Topics: Another morning waiting for the fall of Roe Debriefing on the bipartisan framework for new gun safety measures (are we dreaming?!) and how to balance cynicism while taking the W Why closing the boyfriend loophole is actually a big f*cking deal Our criteria for whether the January 6th hearings have been effective Learn more about Kellie Leeson and the New York primary at kellieforassembly.com
PWTorch editor Wade Keller is joined by Kelly Wells from PWTorch to discuss WWE Friday Night Smackdown with live callers including the announced Roman Reigns vs. Riddle match for the title next week, Sheamus vs. Drew McIntyre going to a double countout, Ronda Rousey vs. Shotzi, Roman Reigns's schedule in general lately, Gunther capturing the IC Title from Ricochet, and more.
Time has indeed passed, the clock continues to tick—AKA Jordana, Aleen, and Sami don't have a ton of updates from the last time we all chatted. So, onto pop culture we go. Sami starts off by debriefing Julia Haart's new book (re: the My Unorthodox Life star), and there's a lot to discuss. No, it's not PG, and Aleen even spits out her coffee after hearing one of the sex stories—you'll def want to tune in. Back to PG programming, they segue onto celeb kids and discuss celeb parenting styles—think Prince Louis at the Platinum Jubilee and Pete Davidson taking Saint West on an outing sans Kim K. They wrap up by asking the big q we all wanna know: did Kylie Jenner name her baby yet?
Joining the Deux U classroom this week is Sami Sage. Sami is the Co-Founder and CCO of Betches Media, host of the Betches Sup and Morning Announcements podcasts and pop culture enthusiast. We're discussing the week's hottest topics, including: A popular actress gets engaged Possible Return of a Bridgerton Star A lead on Rihanna's baby name Sandra Bullock's Hospitality Michael B. Jordan - Dating & breakup update How to attend a party at Drake's house Listen for never-before-heard or read information! Follow Deux @Deuxmoi Learn more about your ad choices. Visit podcastchoices.com/adchoices
This week we're joined by the bad boys of Perth Comedy, MIKE GOLDSTEIN and SAMI SHAH! Tommy's received a devastating message from a relative regarding the Make A Wish foundation so we spend a lot of time brainstorming a response. Chandler's about to head off to Thailand - coincidentally, the location of Sami's wedding, which he graciously unpacks for us. PLUS we've all had weird Uber driver experiences, Sami's had an eventful haircut and Chandler dives into the ‘other messages' folder! See acast.com/privacy for privacy and opt-out information.