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To know where you're going, you need to understand where you've been. This week, we asked Adam J. Brown, MD, the host of the Rheumination's podcast, to share with us how understanding the evolution of rheumatology informs his clinical observations. Dr. Brown brings us to the founding of rheumatology and covers the major milestones, discoveries, the ground-breaking pioneers and how this bold legacy has shaped the current state of our field.
In this conversation, Daniel Belkin and Mitch Belkin interview Adam J Brown, MD about the field of Rheumatology, autoimmune diseases, and his podcast Rheuminations. They discuss the history of gout, plaquenil, the relationship between infectious diseases and rheumatologic conditions, the inflammasome, autoinflammatory disorders, vasculitis, fibromyalgia, Covid, and much more.Who is Adam J Brown?Dr. Adam J. Brown is a Rheumatologist at the Cleveland Clinic. Dr. Brown is the author of the book Rheumatology Made Ridiculously Simple. He is also the host of the Healio podcast Rheuminations, which focuses on autoimmunity, rare diseases, and the history of medicine. References:Twitter - @AdamJBrownMDAdam J Brown's Quiz Platform Rheum and BoardsHealio Rheuminations Podcast Support the showFollow us at @ExMedPod Subscribe to our Youtube channelConsider supporting us on Patreon
This podcast series is sponsored by Vectra®. Discussion does not constitute or imply endorsement of the product. In this episode, Adam J. Brown, MD, and Leonard H. Calabrese, DO, discuss how rheumatologists can evaluate their patients for cardiovascular risk, how to counsel patients about risk factors, and the role of general wellness and wellbeing in the management of rheumatoid arthritis. Intro 0:11 Today's episode 0:32 Intro of Dr. Leonard H. Calabrese 0:48 How do you discuss cardiovascular risk with RA patients? 2:07 When do you bring up the topic of cardiovascular risk with a patient? 5:18 What lifestyle changes do you discuss with RA patients concerned about cardiovascular risk? 7:36 How do you address fatigue when discussing lifestyle adjustments with patients? 12:35 When fatigue lingers despite effective therapeutics 15:49 The importance of adopting wellness behaviors 18:00 Empowering patients to make lifestyle modifications 21:03 Thanks for listening 23:04
This podcast series is sponsored by Vectra®. Discussion does not constitute or imply endorsement of the product. In this episode, Adam J. Brown, MD, and Jeffrey Curtis, MD, discuss the multiple biomarkers associated with cardiovascular risk in rheumatoid arthritis, as well as the reasoning behind the development of a biomarker-based cardiovascular risk model. Intro :10 Intro of Dr. Jeffrey Curtis :22 Today's episode :56 Tell us about your background and how you got to where you are? 3:29 What do rheumatologists need to be using other than existing score-based systems to predict cardiovascular risk? 5:06 Are traditional risk factor calculators helpful? What are they missing? 6:32 Considering disease level/activity when looking at overall cardiovascular risk 8:07 A high-level look at multiple biomarker-based tests 9:38 How were the 12 individual biomarkers originally selected? 11:42 How do you go about implementing the test? How do you get patients? 17:23 How is the test ordered and how do you walk a patient through it? 19:48 How is the timeframe based? 21:56 When are physicians ordering this test? 23:46 The use of biomarker information in educating patients about additional risk factors 26:36 What's going into the score generated by test? 27:36 How to use the resulting score in conversations with patients 28:19 Additional work and responsibility for rheumatologists as a result of this test being available 30:16 Thanks for listening 33:17 Additional work and responsibility for rheumatologists as a result of this test being available 31:45 Thanks for listening 34:50
This podcast series is sponsored by Vectra®. Discussion does not constitute or imply endorsement of the product. In this episode, Adam J. Brown, MD, and Jon Giles, MD, explore the history of cardiovascular risk in rheumatoid arthritis from the 1950s onward, including the emergence of data surrounding inflammation and cardiovascular disease, as well as the need for therapeutics that go beyond simply treating joint pain. Intro :11 Intro of Dr. Jon Giles :22 Today's episode 1:36 How did you become interested in cardiovascular disease in rheumatology? 2:18 When did cardiovascular risk become part of the discussion about RA? 4:33 How to follow patients over time and develop a better sense of cardiovascular risk through studies. 7:23 Are there unique cardiovascular risk factors among RA patients? 10:19 CRP levels as predictive of cardiovascular events 12:09 The biology behind cytokines associated with cardiovascular risk 14:22 Are current interventions and therapeutics making a difference? 16:27 General awareness among patients and physicians of cardiovascular disease and RA 18:29 Roles and responsibilities in cardiovascular risk management 21:15 How do we screen for cardiovascular risk beyond lipid panels? 22:27 Where is the field of cardiovascular risk and RA going? 24:01 Steroids, NSAID's, and cardiovascular risk 25:43 Episode wrap up 27:04 Thanks for listening 27:49
This episode walks us through the initial research that paved the way for a game changing therapeutic in ANCA vasculitis, as well as the story of how host Adam J. Brown, MD, finally learned how to spell complement. Brought to you by GSK. Considering a treatment change for patients with active SLE? Learn about a treatment option for your patients at treatfortodayandtomorrow.com. Intro :10 Welcome :21 Today’s episode :24 So how did we get there? 4:18 How do we start teasing apart the effect of the complement in ANCA vasculitis? 8:13 Discussing and simplifying the mouse model 9:00 Quickly reviewing the complement cascade 12:06 Brought to you by GSK. Consider the long-term impact of disease activity flares and corticosteroid use on patients with active SLE. Learn more now at treatfortodayandtomorrow.com. Taking the puzzle pieces away in the mouse model 17:04 What about the next steps? 22:05 What happens when you block C5a? 25:12 CCX168: Summing up the mouse tale 28:44 In the next episode 30:20 Thanks for listening 30:46 Disclosures: Brown reports no relevant financial disclosures. We’d love to hear from you! Send your comments/questions to Dr. Brown at rheuminationspodcast@healio.com. Follow us on Twitter @HRheuminations @AdamJBrownMD @HealioRheum References: Brilland B, et al. Autoimmun Rev. 2020;19:102424. Freeley SJ, et al. J Pathol 2016;240:61-71. Haas M, Eustace JA. Kidney Int 2004;65:2145-2152. Huugen D, et al. Kidney Int 2007;71:646-654. Marder SR, et al. Arg. J Immunol. 1985;134:3325-3331. Schreiber A, et al. J Am Soc Nephrol. 2009;20:289-298. Xiao H, et al. Am J Pathol. 2007;170:52-64. Xiao H, et al. J Clin Invest 2002;110:955–963. Xiao H, et al. J Am Soc Nephrol, 2014;25:225–231.
The History of Rheumatology In this episode of RheumCast, RNS President, Cathy Patty-Resk, MSN, RN-BC, CPNP-PC, interviews Cleveland Clinic’s, Dr. Adam J. Brown. Tune in to find out what disease was officially proven a rheumatic disease by rheumatologists injecting their knees in the 1960s as an experiment. QUICK CONNECTS~~> Host: Cathy Patty-Resk on Twitter: @RNSPresident~~> Guest: Dr. Adam J. Brown on Twitter: @AdamJBrownMD~~> Resource: Rheuminations podcast on Apple Podcasts/iTunes~~> Resource: Rheuminations podcast on Healio Rheumatology~~> Rheumatology Nurses Society (RNS) website: https://RNSnurse.org~~> RNS on Twitter: @RNSociety~~> RNS on Facebook: RheumNurses~~> RNS on Instagram: RheumatologyNurses~~> Free RNS Guest Membership: https://RNS.news/podcastguest - - - - - - - RNS GUEST Dr. Adam J. Brown is an associate staff physician in the department of rheumatic and immunologic diseases at Cleveland Clinic, covers quick updates in the field of autoimmunity, with emphasis on new medications, treatment guidelines, and explorations into the pathophysiology of diseases. Dr. Brown is the host of Rheuminations, a podcast series focusing on medical mysteries and other ripping yarns of the immune system gone awry. RNS HOST Cathy Patty-Resk, MSN, RN-BC, CPNP-PC is the current President of the Rheumatology Nurses Society. Cathy currently resides in Michigan where she works as a nurse practitioner at Children’s Hospital of Michigan in Detroit. She studied nursing at Wayne State University and has been practicing rheumatology since 2009. Cathy is recognized as a board-certified pediatric nurse practitioner, board-certified rheumatology nurse, President of the RNS, and an active member of the legislative advocacy team. She has served as the co-editor of and a contributor to the Core Curriculum for Rheumatology Nursing. Cathy currently serves as a founding executive board member of The Alliance for Transparent & Affordable Prescriptions (ATAP) and an advisory board member to The Pediatric Rheumatology Collaborative Study Group (PRCSG). She enjoys teaching nurse practitioner students pediatric rheumatology, getting them actively involved in real legislative advocacy, and often continues serving as a mentor assisting with ongoing professional development and leadership. - - - - - - - WHO WE ARE The Rheumatology Nurses Society (RNS) is a non-profit professional nursing and advanced practice provider (APP) organization representing registered nurses (RNs), nurse practitioners (NPs), physician assistants (PAs), and other healthcare professionals who are engaged in clinical practice, education, and research for the care of patients with rheumatic diseases. Sign up for a free RNS Guest Membership and gain access to educational offerings and be informed about upcoming events, news in rheumatology, and stories from our team. Sign up today at https://RNS.news/podcastguest
At a time when many educators are challenging the value, efficacy, and process of grading, our guest points the way toward using grading to improve learning. Follow: @susanbrookhart @adamBrownEDU @ASCD @bamradionetwork Susan Brookhart is the author of How to Use Grading to Improve Learning and currently serves as an adjunct faculty member in the School of Education at Duquesne University. Adam J. Brown Ed.D., an ASCD Emerging Leader, is a principal Re-ED/TRAEP- Virginia Beach SECEP at Renaissance Academy.
Join us for a practical discussion about equity in our schools, why equity is important ,and how to move the equity discussion from concept to reality. Follow: @AdamBrownEDU @donsmithrp @NancyFrey @ASCD @bamradionetwork Nancy Frey is a professor of educational leadership at San Diego State University. Frey also teaches classes at Health Sciences High and Middle College in San Diego. Dominique Smith is the director of student services at Health Sciences High & Middle College, where he also serves as a culture builder and student advocate. Adam J. Brown Ed.D., an ASCD Emerging Leader, is a principal Re-ED/TRAEP- Virginia Beach SECEP at Renaissance Academy.
Join us as we unpack the top six leadership behaviors that drive optimism and commitment. Follow: @bobbdarnell @adambrownedu @ASCD @bamradionetwork Bobb Darnell is president of Achievement Strategies Inc., an ASCD faculty member, and an advocate for high student achievement and daily professional growth. Emerging leader Matt Wachel is an elementary assistant principal in the Park Hill School District in Kansas City, MO. Adam J. Brown Ed.D., an ASCD Emerging Leader, is a principal Re-ED/TRAEP- Virginia Beach SECEP at Renaissance Academy.
Join us as we unpack the top six leadership behaviors that drive optimism and commitment. Follow: @bobbdarnell @adambrownedu @ASCD @bamradionetwork Bobb Darnell is president of Achievement Strategies Inc., an ASCD faculty member, and an advocate for high student achievement and daily professional growth.eader Matt Wachel is an elementary assistant principal in the Park Hill School District in Kansas City, MO. Adam J. Brown Ed.D., an ASCD Emerging Leader, is a principal Re-ED/TRAEP- Virginia Beach SECEP at Renaissance Academy.