Class of diseases that involve the heart or blood vessels
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Vitamin K2 (MK-7) and Coronary Artery Calcification: Insights from a 2-Year Trial: Nutritionist Leyla Muedin discusses a two-year randomized clinical trial in JAMA Cardiology from Maastricht University Medical Center reporting that daily vitamin K2 (menaquinone-7, MK-7) at 360 mcg slowed progression of coronary artery calcification (CAC) in 180 patients with confirmed atherosclerotic cardiovascular disease and baseline CAC 50–400 Agatston units. Compared with placebo, consistent MK-7 use was associated with 29% lower CAC progression and 42% less arterial calcium mass progression, though CAC still increased in both groups; stenosis increases were numerically lower with MK-7 but not statistically significant. Leyla notes many participants were on statins and were smokers, highlighting that statins can raise CAC by stabilizing soft plaque via calcification. The trial suggests MK-7 may slow calcification in newer plaques, may improve arterial elasticity via matrix GLA protein activation, is inexpensive and safe, but clinical event reduction remains unproven; Leyla suggests considering MK-7 (possibly 360 mcg) with vitamin D, magnesium, and dietary measures.
Sharonne N. Hayes joins host Saranya Ravindran to discuss how cardiovascular disease presents differently in women. From pregnancy-related complications and menopause to microvascular disease and gaps in clinician education, this episode explores the importance of sex-specific cardiovascular care. Timestamps: 1:04 – Sex-specific differences 2:43 – Pregnancy and preeclampsia 4:38 – Historic underdiagnosis 7:00 – Menopause and hormones 10:04 – Education and training
The World Cup is here, and while we watch some of the world's greatest athletes competing on a global stage, it's fascinating to consider what effect this intense activity may have on the human body. With that in mind, we're re-releasing our conversation with Stanford biochemist Jonathan Long on the future of exercise. Jonathan studies the chemistry of what happens inside your body when you move, and his findings are pointing toward some genuinely surprising possibilities — including treatments for obesity, diabetes, and even, someday, an exercise pill. If the athleticism on the pitch has you feeling inspired, this one is well worth another listen. Have a question for Russ? Send it our way in writing or via voice memo, and it might be featured on an upcoming episode. Please introduce yourself, let us know where you're listening from, and share your question. You can send questions to thefutureofeverything@stanford.edu. Episode Reference Links: Stanford Profile: Jonathan Long Connect With Us: Episode Transcripts >>> The Future of Everything Website Connect with Russ >>> Threads / Bluesky / Mastodon Connect with School of Engineering >>> Twitter/X / Instagram / LinkedIn / Facebook Chapters: (00:00:00) Introduction Russ Altman introduces guest Jonathan Long, a professor of pathology from Stanford University. (00:02:02) Effective Weight Loss Drugs The history and development of GLP-1 receptor agonists. (00:04:04) Understanding Metabolism and Exercise Why Long's lab starts with molecules to understand metabolism and physical activity. (00:05:10) Animal Models in Exercise Studies The use of animal models in exercise studies and the discovery of Lac-Phe. (00:06:47) Psychological Preparation for Exercise The psychological aspects of exercise and the involvement of endocannabinoids in exercise motivation. (00:09:00) Lac-Phe's Role and Mechanism The role of Lac-Phe and its production in the gut. (00:12:08) Differences in Exercise Response Differences in exercise response between trained athletes and untrained individuals. (00:12:57) Diabetes and Metabolic Diseases The relationship between diabetes, exercise, and metabolic diseases. (00:15:01) Lac-Phe as a Potential Therapeutic The potential of Lac-Phe as a weight loss drug, and parallels to GLP-1 drug development. (00:16:21) Importance of How Weight is Lost Whether the method of weight loss matters, and the importance of preserving lean muscle mass. (00:18:37) Exercise as Medicine The concept of exercise as medicine, and defining physical activity at the same resolution as modern medicines. (00:22:11) Metformin and Exercise Pathways The unexpected connection between metformin and the Lac-Phe pathway. (00:24:01) Prospects of an Exercise Pill The future of an exercise pill, and the challenges associated with its development. (00:27:05) Conclusion Final thoughts on the future of exercise. Connect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads / Bluesky / MastodonConnect with School of Engineering >>>Twitter/X / Instagram / LinkedIn / Facebook Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
Free course: Improve your metabolic healthGet our free email course on how glucose, nutrition, exercise, sleep, and measurement can help you build habits that support better energy and long-term health: https://levels.link/wnlHigh cholesterol. Elevated ApoB. A positive CAC score. Now what?Most people quickly find themselves trapped between two extremes: simplistic advice to “cut saturated fat” and online influencers insisting cholesterol doesn't matter at all.In this episode of A Whole New Level, Mike Haney sits down with clinical research scientist Dr. Kevin Maki to cut through the confusion.Drawing on more than 35 years of cardiovascular research, Maki explains why heart disease risk is about much more than LDL cholesterol alone. He breaks down the roles of inflammation, blood sugar, family history, kidney function, and lipoproteins, while also making a clear case for something many people resist: LDL and ApoB still matter. A lot.The evidence increasingly suggests that when it comes to atherosclerosis, lower for longer is better. That has important implications for diet, statins, and how early we should intervene.Mike and Dr. Maki also tackle saturated fat, seed oils, red meat, industry-funded research, and how to separate evidence from online nutrition debates.
In this episode, we sit down with Dr. Gene Sambataro, a biological dentist with over 40 years of experience, to explore how oral health is deeply connected to whole-body health. He explains how issues in the mouth—such as microbiome imbalance, mercury fillings, fluoride exposure, and toxic root canals—can contribute to systemic disease and chronic inflammation. The conversation dives into airway-focused dentistry, including narrow jaws, TMJ dysfunction, teeth grinding, Malampati scores, and how these factors relate to sleep-disordered breathing and conditions like sleep apnea. Dr. Sambataro also breaks down modern diagnostic tools like 3D cone beam imaging and sleep studies, along with practical approaches such as oral appliances, breathing techniques, and addressing hypoxia. He closes by emphasizing critical thinking in health care, the importance of restoring proper breathing during sleep, and integrating advanced regenerative and biohacking tools into dentistry for long-term wellness.Dr. Gene Sambataro has been practicing dentistry for over 40 years with a focus on orthodontics, dental orthopedics, TMJ disorders, sleep-disordered breathing, cosmetic/facial aesthetics, toxic-free dentistry, and ceramic implantology. He graduated from the University of Maryland School of Dentistry in 1980, completed a hospital residency in Baltimore, and transitioned into private practice where he quickly adopted a more holistic, integrative approach to dentistry. He is a leading advocate of biological dentistry, emphasizing the connection between oral health and systemic disease and promoting toxin-free approaches such as avoiding mercury amalgams, fluoride, and toxic root canals. He trained with Dr. Hal Huggins early in his career and continues to follow the Huggins Protocol in his clinical practice. His professional affiliations include multiple dental and integrative medicine organizations, along with training in sleep medicine and TMJ therapies, and he is also an author and ongoing student of advanced scientific and regenerative fields. Outside of dentistry, he incorporates biohacking and healing technologies into his practice, has been married for 45 years to his wife Cindy, while also holding advanced martial arts black belts in Taijitsu and Ninjitsu.SHOW NOTES:0:38 Welcome to the show!3:13 About Dr. Sambataro4:02 Welcome him to the podcast!5:28 Does high blood pressure start in the mouth?7:13 Issues with mouthwash9:31 Root causes of a poor microbiome13:47 Specialized medicine & Oral Physicians18:08 How the mouth is a window into the body20:02 Narrow jaw & crowded teeth21:23 Teeth grinding & appliances23:59 Malampati scores24:30 3D Cone Beam 26:30 Solutions for airway issues30:35 Cone Beam 101 & Why you would get one35:47 Sleep studies43:40 Sleep-disordered breathing48:27 Health risks of hypoxia & sleep apnea49:45 What to do with “moderate” issues54:39 Breathing techniques for sleep apnea57:42 Garage analogy59:12 Vitamin O1:00:33 Critical thinking & AI1:05:55 His final piece of advice1:07:32 The Julian Center 1:08:20 Thanks for tuning in!RESOURCES:Website: The Julian CenterIG: @julian_dentistIG: @drgenesambataroFacebook: The Julian CenterBook: Stop the SnoreBook: Your Guide to Holistic Dental ImplantsSupport this podcast at — https://redcircle.com/biohacker-babes-podcast/donationsAdvertising Inquiries: https://redcircle.com/brands
More than just a game—Knicks overcoming odds in game 4 comeback is a parable of resilience; A one and done lifetime cholesterol fix via gene modification; Will cataract surgery interfere with benefits of light exposure? Do amounts of vitamin A in various supplements taken together court the risk of toxicity? Smartphones and social media create real harm for adolescents; Experts determine the exact right amount of sleep down to the minute—but is it overreach?
Could you have metabolic dysfunction even at a normal weight?This episode challenges everything we've been taught about weight and health. Dr. Cooper reveals that up to 25% of normal-weight people have metabolic syndrome, yet they're rarely screened because doctors assume they're healthy based on appearance alone.KEY TAKEAWAYSWeight and metabolic health are not the same thing - you can be metabolically unhealthy at any sizeNormal weight people with metabolic dysfunction are often overlooked and undertreated by healthcare providersKey screening tests include fasting glucose, insulin, HbA1c, triglycerides, HDL cholesterol, blood pressure, and inflammatory markers like HSCRPMetabolic dysfunction can start in your 20s and take decades to develop into serious diseaseBoth normal weight and higher weight patients face bias - normal weight people aren't screened enough, while higher weight people have everything blamed on their weightEarly screening and treatment can prevent catastrophic health outcomes later in lifeThe liver plays a crucial role in metabolism and can become insulin resistant regardless of body weightNOTABLE QUOTE"You cannot tell anything about someone's health from their outside, what they look like or what, even what they're doing necessarily, but definitely not their body size. So you can be healthy or unhealthy at any size body, and I think that's what's overlooked quite a bit." — Dr. Emily CooperLinks & ResourcesPodcast Home: fatsciencepodcast.comCooper Center for Metabolism: coopermetabolic.comResources from Dr. Cooper: coopermetabolic.com/resourcesJoin Our Community: patreon.com/cw/FatSciencePodcastSubmit Your Question: questions@fatsciencepodcast.com or dr.c@fatsciencepodcast.comAppendix: Key ReferencesPrimary literature supporting this episode• Wang et al. Prevalence of Metabolically Unhealthy Normal Weight and Its Influence on the Risk of Diabetes. Journal of Clinical Endocrinology & Metabolism, 2023.• Review: Beyond BMI — Rethinking Obesity Metrics and Cardiovascular Risk in the Era of Precision Medicine. Journal of Clinical Medicine, December 2025.• Korean meta-analyses on metabolic dysfunction phenotypes and cardiometabolic risk, Cardiovascular and Metabolic Sciences Journal review, 2024.• Frontiers in Nutrition, January 2026. Associations of metabolic heterogeneity with the progression of cardiometabolic multimorbidity.• International Journal of Obesity, September 2025. Cardiovascular risk factors associated with metabolic health phenotypes.Mechanism references• MASLD — metabolic dysfunction-associated steatotic liver disease — nomenclature and clinical framework. AASLD/EASL consensus, 2023.• Insulin signaling, adipose tissue dysfunction, and ectopic fat deposition — reviews on the upstream-downstream relationship.• Epicardial adipose tissue and cardiovascular dysfunction — Frontiers in Cardiovascular Medicine, January 2026.Fat Science is supported by the Diabesity Institute, a nonprofit dedicated to increasing access to effective, science-based metabolic care.This podcast is for informational purposes only and is not intended as medical advice. Please consult with a qualified healthcare provider for personalized recommendations.
In Part 2, Naveed Sattar discusses obesity, ectopic fat, and cardiovascular risk. Learn how imaging and biomarkers are improving risk identification, why metabolic dysfunction matters beyond BMI, and how GLP-1 therapies are reshaping obesity and cardiovascular care. Timestamps: 0:56 – Ectopic fat 11:44 – Metabolic dysfunction 13:42 – GLP-1 receptor agonists 19:05 – Mechanistic insights 21:31 – Societal issues
Guest: John W. Ostrominski, MD, MPH Despite advances in glycemic management, blood pressure control, lipid lowering, and disease-modifying therapies, patients with chronic kidney disease (CKD) and type 2 diabetes continue to face substantial residual cardiovascular risk. In this program, Dr. John Ostrominski reviews emerging evidence linking low-grade systemic inflammation to adverse cardiovascular outcomes in this high-risk population, highlighting findings from the FIDELITY pooled analysis of FIDELIO-DKD and FIGARO-DKD. Dr. Ostrominski is a fellow specializing in cardiovascular disease and obesity medicine at Brigham and Women's Hospital and Harvard Medical School. He spoke about this topic at the 2026 American Diabetes Association Scientific Sessions.
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Cholesterol found in your blood is just the beginning of the story when it comes to markers found there that are indicative of cardiovascular risk. A relative newcomer is apolipoprotein a, which is genetically determined, says Roger Blumenthal, a cardiologist … What markers are found in blood that indicate cardiovascular risk? Elizabeth Tracey reports Read More »
Drs. McMahon and Kalunian discuss how patients with lupus nephritis face a markedly higher risk of cardiovascular disease and how traditional risk calculators fail to capture the added danger from chronic inflammation, steroids, and disease-specific factors. They call for a paradigm shift toward aggressive, early, and continuous cardiovascular protection—including tighter blood pressure targets, earlier statin use, lifelong hydroxychloroquine when possible, and close multidisciplinary management from the time of diagnosis.
Soon-to-arrive drugs promise to address elevated Lp(a); Best natural alternatives to repel mosquitoes and ticks; When cancer treatments cause osteoporosis; Organoids and computer simulations promise to reduce the toll of live animal experimentation; Land snails and pythons yield clues for new drug development; Shortfall in doctors accelerated by early retirement as physicians cite “hassle factor.”
The most important person in reducing your risk for cardiovascular disease is you, and managing your blood cholesterol levels is just one part of an overall, lifelong strategy, beginning with becoming educated about your own unique set of risk factors. … Becoming educated about your own cardiovascular risk is pivotal to prevention, Elizabeth Tracey reports Read More »
Welcome back to this week's Friday Review where I can't wait to share with you the best of the week! I'm looking forward to reviewing: 3 Product Review Updates Progress Should Feel Sustainable (tip of the week) HRT & Cardiovascular Risk (research) Reducing Biological Age & Cancer (research) For all the details tune into this week's Cabral Concept 3759 – Enjoy the show and let me know what you thought! - - For Everything Mentioned In Today's Show: StephenCabral.com/3759 - - - Get a FREE Copy of Dr. Cabral's Book: The Rain Barrel Effect - - - Join the Community & Get Your Questions Answered: CabralSupportGroup.com - - - Dr. Cabral's Most Popular At-Home Lab Tests: > Complete Minerals & Metals Test (Test for mineral imbalances & heavy metal toxicity) - - - > Complete Candida, Metabolic & Vitamins Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Complete Stress, Mood & Metabolism Test (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Complete Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Complete Omega-3 & Inflammation Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels) - - - Get Your Question Answered On An Upcoming HouseCall: StephenCabral.com/askcabral - - - Would You Take 30 Seconds To Rate & Review The Cabral Concept? The best way to help me spread our mission of true natural health is to pass on the good word, and I read and appreciate every review!
Highlights from Dr. Hoffman's Scandinavian tripShould I eliminate the nightshade family of foods from my diet?My friend has been experiencing acid reflux since using a reverse osmosis water filtration system
We know diet and exercise matter—but what about medications for prevention? Credit available for this activity expires: 5/20/27 Earn Credit / Learning Objectives & Disclosures: https://www.medscape.org/viewarticle/episode-4-beyond-lifestyle-managing-cardiovascular-risk-2026a1000fuk?ecd=bdc_podcast_libsyn_mscpedu
We have only recently become aware of the close relationship between the heart and the kidneys. In today's discussion, Dr. Neil Skolnik speaks with Dr. Josephine Harrington to gain insight into these newly-discovered links between cardiovascular risk and CKD. This special episode is sponsored with support from Bayer. Please listen to the episodes by clicking on the podcast player below or by freely subscribing to Diabetes Core Update via Apple Podcasts, Amazon Music, Spotify, or your preferred podcast platform. Presented by: -Neil Skolnik, MD, Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington Jefferson Health -Josephine Harrington, M.D., Assistant Professor of Medicine in the Division of Cardiology at the University of Colorado School of Medicine. Selected references: -Chronic Kidney Disease and Risk Management: Standards of Care in Diabetes—2026. The American Diabetes Association's Standards of Care 2026, Diabetes Care 2026;49 (Supplement_1):S246–S260 -Effect of Finerenone on Chronic Kidney Disease Outcomes in Type 2 Diabetes. N Engl J Med 2020;383:2219-2229 -Dapagliflozin in Patients with Chronic Kidney Disease. N Engl J Med 2020;383:1436-1446 -Effects of Semaglutide on Chronic Kidney Disease in Patients with Type 2 Diabetes. N Engl J Med 2024;391:109-121
The Real Truth About Health Free 17 Day Live Online Conference Podcast
Excess visceral fat fuels inflammation, autoimmune disease, and cancer—while modern medicine often treats only the symptoms. #VisceralFat #ChronicDisease #RootCauseHealing
A case study where a second opinion is necessaryWhat are your thoughts on the recent news implicating niacin in cardiovascular disease?
The Real Truth About Health Free 17 Day Live Online Conference Podcast
From reversing fatty liver in children to understanding LDL and HDL, Dr. Marbas uses case studies to show the power of plant-based diets. #LiverHealth #Cholesterol #HeartHealth #NutritionStories
The Real Truth About Health Free 17 Day Live Online Conference Podcast
Step into a full reversal protocol—diet, biomarkers, salt use, stress reduction—and learn why even ideal lifestyles require flexibility and joy. #HeartReversal #PlantBasedHealing #LifestyleMedicine #HealthTalks
GLP-1 receptor agonists like semaglutide are often described as “game changers” for weight loss and cardiovascular health, and in many ways, the data support that claim. Clinical trials suggest meaningful reductions in major cardiovascular events, offering hope for individuals struggling with metabolic disease.But there's an important nuance that deserves more attention: what happens when these medications are stopped?In this conversation, Dr. Bret Scher explores emerging real-world data showing that the benefits of GLP-1s, particularly for cardiovascular risk, appear to depend on continued use. For many individuals, stopping the medication leads to a reversal of progress, raising important questions about long-term strategy, sustainability, and what true metabolic healing looks like.Are we managing symptoms, or addressing root causes?What role should medications play in long-term care?How can we use powerful tools like GLP-1s to support, rather than replace, sustainable metabolic change?For some individuals, long-term use may be appropriate and beneficial. But we need to broaden the conversation toward approaches that aim to improve underlying metabolic health, support lasting behavior change, and ultimately reduce reliance on lifelong interventions when possible.If you're exploring GLP-1s or are currently taking one, consider speaking with your healthcare provider about how to pair your treatment with sustainable lifestyle strategies such as nutrition, physical activity, and metabolic support, to help maintain progress over time.
The benefits of saunaThe Take Back Your Health TourA follow-up on milk thistle interactions with drugsWhat are your thoughts on low-dose saw palmetto for hair growth?Is monk fruit a safe sweetener to use?
Would strontium help in the healing of lumbar fractures? How about as a preventive?How valuable is the hs-CRP test? Are there any drawbacks to eating canned fish?What are your thoughts on Arterosil for cardiovascular health?
Master athletes challenge one of medicine's most elegant assumptions: that fitness always protects. In the Journal of the American College of Cardiology (JACC) consensus statement on athletes with abnormal cardiovascular findings, a paradox emerges—higher fitness, yet distinct patterns of risk: atrial fibrillation, coronary calcium, myocardial fibrosis. The lesson is not to discourage exercise—but to refine our lens. For the clinician: risk stratification must be individualized. For the athlete: performance and prudence must coexist.
A trial found that discontinuing beta-blockers in stable post-MI patients without heart failure was noninferior to continuing them, suggesting long-term use may be unnecessary. Second, the 2026 ACC/AHA lipid guideline promotes earlier, personalized intervention using the PREVENT risk calculator and expanded biomarkers to reduce lifetime cardiovascular risk. Finally, a JAMA study found thiazide diuretics carry meaningful hyponatremia risk, especially in older adults and women, urging careful patient selection
Heart Association clashes with RFK, Jr., doubles down on recommendation for low-fat diets; Why the evidence for meat and full-fat dairy avoidance is weak; What are the health benefits of circumcision? The ultimate weight loss plan—the Boring Diet; Substituting famotidine for PPIs for reflux; Midlife vitamin D curbs Alzheimer's risk; Natural support for polymyalgia rheumatica; What teens eat could be affecting their mental health.
Leyla Muedin, a registered dietitian nutritionist, discusses a UK Biobank analysis published in the Journal of Cachexia, “Sarcopenia and Muscle” (Nov 2025) linking continuous long-term statin use (e.g., Lipitor, Zocor, Crestor) to accelerated declines in grip strength and appendicular lean mass compared with never-users. Among 35,557 with follow-up data, grip strength declined by a mean 0.315 kg/year and appendicular lean mass by 0.057 kg/year in statin users; findings persisted after adjustment for age, sex, BMI, comorbidities, and a pharmacogenomic statin-response score. Leyla notes possible mechanisms (CoQ10/mevalonate pathway effects, mitochondrial dysfunction, apoptosis, calcium disruption, insulin resistance) and advises monitoring musculoskeletal health, supporting diet and regular physical activity, while not interpreting results as a reason to stop prescribing statins.
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Animal products contain aging toxins like dioxins and PCBs. Learn how a plant-based, SOS-free diet dramatically slows cellular aging. #PlantBased #AntiAging #Toxins #HealthTalks
Discover all of the podcasts in our network, search for specific episodes, get the Optimal Living Daily workbook, and learn more at: OLDPodcast.com. Episode 3308: Dr. Neal Malik explains why atherosclerosis can persist even with statins, diet, and lifestyle changes, highlighting the role of genetics, particularly elevated lipoprotein(a), in stubborn plaque buildup. His guidance emphasizes practical strategies like targeted fat choices, fiber intake, and realistic exercise plans to help reduce risk and prevent further progression. Quotes to ponder: "The trouble is, once this plaque, or atherosclerosis, sets in, it's not reversible through lifestyle alone." "It's estimated that about 1 in 5 Americans have high levels of lipoprotein-a." "Fiber is so helpful because it binds to cholesterol and helps the body get rid of it." Episode references: Omega-3 Fatty Acids – NIH Office of Dietary Supplements: https://ods.od.nih.gov/factsheets/Omega3FattyAcids-Consumer/ Learn more about your ad choices. Visit megaphone.fm/adchoices
Discover all of the podcasts in our network, search for specific episodes, get the Optimal Living Daily workbook, and learn more at: OLDPodcast.com. Episode 3308: Dr. Neal Malik explains why atherosclerosis can persist even with statins, diet, and lifestyle changes, highlighting the role of genetics, particularly elevated lipoprotein(a), in stubborn plaque buildup. His guidance emphasizes practical strategies like targeted fat choices, fiber intake, and realistic exercise plans to help reduce risk and prevent further progression. Quotes to ponder: "The trouble is, once this plaque, or atherosclerosis, sets in, it's not reversible through lifestyle alone." "It's estimated that about 1 in 5 Americans have high levels of lipoprotein-a." "Fiber is so helpful because it binds to cholesterol and helps the body get rid of it." Episode references: Omega-3 Fatty Acids – NIH Office of Dietary Supplements: https://ods.od.nih.gov/factsheets/Omega3FattyAcids-Consumer/ Learn more about your ad choices. Visit megaphone.fm/adchoices
A sudden loss can shake even the most grounded among us.In this deeply personal solocast, Dr. Ritamarie reflects on the unexpected death of a colleague in the natural health community and the vulnerability it surfaced. When someone who appears healthy dies suddenly, it forces a difficult but necessary question: what silent risks might be accumulating beneath the surface?This episode explores the quiet progression of cardiovascular disease, the limitations of standard lab panels, and why doing everything “right” is not the same as measuring what matters. Dr. Ritamarie shares her own experience with elevated lipoprotein(a), what she did in response, and why awareness is not fear, it is responsibility.If you are a practitioner, this conversation is a reminder to screen earlier and look deeper. If you are on your own health journey, it is an invitation to measure what matters before symptoms ever appear.What's Inside This Episode?Why sudden death in “healthy” people feels different and what it revealsThe silent progression of cardiovascular disease over decadesWhy standard cholesterol panels miss critical risk markersWhat lipoprotein(a) is and why most doctors never test for itHow inflammation, insulin resistance, and endothelial dysfunction quietly accumulateDr. Ritamarie's personal experience lowering elevated Lp(a)Why genetics influence risk but do not dictate destinyThe difference between helplessness and awarenessWhat practitioners should be screening for now, not laterA powerful question to ask yourself about hidden riskResources and Links:Download the transcript hereDownload our FREE Cardiovascular Risk Assessment GuideJoin the Next-Level Health Practitioner Facebook group here for free resources and community supportVisit INEMethod.com for advanced health practitioner training and tools to elevate your clinical skills and grow your practice by getting life-changing results.Check out other podcast episodes here
Podcasts360, powered by Consultant360, features short interviews with medical professionals about current research, news, and general information for health care providers in 35+ specialties.
Reflections on the Peter Attia/Epstein scandal; How to lower lp(a)—does diet help? What are bio-active peptides? Could they stave off kidney disease? Scientists just tested the fittest 81-year-old in the world—here's what they found; Media erroneously report that intermittent fasting is not effective for weight loss; Sugary drinks may stoke anxiety in teens; Omega-3s support kids' reading fluency and spelling scores; Surprising study shows saturated fats not harmful to kidneys.
Podcasts360, powered by Consultant360, features short interviews with medical professionals about current research, news, and general information for health care providers in 35+ specialties.
Host: Darryl S. Chutka, M.D. Guest: Stephen Kopecky, M.D. We have a variety of pharmacologic options and lifestyle changes we recommend to our patients to reduce their cardiovascular risks. One frequent recommendation is participation in a regular exercise program. One specific type of exercise is high intensity interval training. It's been shown to improve a variety of metabolic parameters. What does high intensity interval training consist of? What are the specific metabolic benefits? Can all patients participate in this type of exercise? What's the recommended duration and frequency of training and how good is patient adherence to interval training? The topic for this podcast is “High Intensity Interval Training and Reducing Cardiovascular Risk” and my guest is Dr. Stephen Kopecky, a preventive cardiologist in the Department of Cardiovascular Disease at the Mayo Clinic. Connect with us! Mayo Clinic Talks Podcast Season 6 | Mayo Clinic School of Continuous Professional Development
Podcasts360, powered by Consultant360, features short interviews with medical professionals about current research, news, and general information for health care providers in 35+ specialties.
The evidence is growing that suggest that microplastics, or more specifically smaller nanoplastics, are triggers for atherosclerotic disease with increased risk for heart attack, stroke, and death. While your doctor wastes your time and money obsessing about cholesterol and statin drugs that should have been discarded decades ago, you need to address the REAL factors that cause heart disease. Add nanoplastics to that list. Thankfully, you can begin to make an impact on your ingestion of plastic particles but may need to re-examine many long-accepted habits.Support the showYouTube channel: https://www.youtube.com/@WilliamDavisMD Blog: WilliamDavisMD.com Membership website for two-way Zoom group meetings: InnerCircle.DrDavisInfiniteHealth.com Books: Super Gut: The 4-Week Plan to Reprogram Your Microbiome, Restore Health, and Lose Weight Wheat Belly: Lose the Wheat, Lose the Weight and Find Your Path Back to Health; revised & expanded ed
In this episode of Wellness at the Speed of Light, Dr. Stefano Sinicropi speaks with Dr. Michael Richman, a double board-certified cardiothoracic surgeon with deep expertise in lipidology and cardiovascular prevention. They unpack why cardiovascular disease remains the leading cause of death for both men and women, and why many people labeled “low risk” are still vulnerable to heart attack or stroke. This audio conversation focuses on how atherosclerosis develops over time, the major drivers of cardiovascular risk, and why genetics play a larger role than most people realize. Dr. Richman explains the practical difference between standard cholesterol testing and particle-based measurements such as LDL-P and ApoB, and why these tests can help identify risk earlier and more accurately. They also address the nocebo effect and the way health misinformation shapes patient beliefs and decision-making. The discussion covers the evidence behind statins, including plaque stabilization and inflammation, as well as common questions about omega-3 fatty acids, niacin, red yeast rice, and calcium scoring. The goal is to give listeners a clearer framework for understanding cardiovascular risk, asking better questions in clinical settings, and taking informed, prevention-focused steps without relying on hype or trends. Guest: Dr. Michael Richman, MD, double board-certified cardiothoracic surgeon and lipidology expert.
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Dr. Williams and Dr. Kahn explore how ketogenic diets and saturated fats impact cardiovascular health and longevity. #KetogenicDiet #SaturatedFat #HeartHealth
Popular media leverage weak study to criticize RFK Jr.'s rethink of standard recommendations for saturated fat avoidance; Poor quality plant-based diets hike cardio risk; A listener complains his lp(a) is going up with age despite his healthy diet, lifestyle; Scientists pinpoint cocoa ingredient that slows aging; Berry proanthocyanidins preserve brain power; Tattooing may promote inflammation, undermine immunity.
Send us a message with this link, we would love to hear from you. Standard message rates may apply. In this episode of Your Checkup, we break down lipoprotein(a) — a largely inherited form of cholesterol that can significantly increase the risk of heart disease and stroke, even when standard cholesterol numbers look normal. We talk about what Lp(a) is, why it matters, who should be tested, and how it helps explain “unexpected” heart events in otherwise healthy people. While Lp(a) can't currently be lowered with diet or exercise, knowing your level allows you and your care team to be more intentional about prevention by aggressively managing other risk factors like LDL cholesterol, blood pressure, and diabetes. We also discuss what the numbers mean, why most people only need to be tested once, and the promising treatments currently being studied that may change care in the future. References (for Show Notes)Nordestgaard BG, Langsted A. Lipoprotein(a) and Cardiovascular Disease. Lancet. 2024;404(10459):1255-1264.Reyes-Soffer G, et al. AHA Scientific Statement on Lipoprotein(a). Arterioscler Thromb Vasc Biol. 2022;42(1):e48-e60.Di Fusco SA, et al. Lipoprotein(a): Risk Factor and Emerging Target. Heart. 2022;109(1):18-25.Nasrallah N, et al. Lp(a) in Clinical Practice. Eur J Clin Invest. 2025:e70127.Greco A, et al. Lipoprotein(a) as a Pharmacological Target. Circulation. 2025;151(6):400-415.Bess C, Mehta A, Joshi PH. All We Need to Know About Lipoprotein(a). Prog Cardiovasc Dis. 2024;84:27-33.Support the showSubscribe to Our Newsletter! Production and Content: Edward Delesky, MD & Nicole Aruffo, RNArtwork: Olivia Pawlowski
Listen in as Jay H. Shubrook, DO, FACOFP, FAAFP, and Chrisopher Weber, MD, FAAP, FACP, CSCS, daBOM, FOMA, discuss the latest advances in caring for patients with overweight or obesity in the primary care setting, including:The Lancet Commission's new obesity definitions and diagnostic criteriaKey data on incretin-based antiobesity medications like semaglutide and tirzepatideBest practices for patient discussionsStrategies for incorporating new evidence in your primary care practicePresentersJay H. Shubrook, DO, FACOFP, FAAFPProfessor and DiabetologistDepartment of Clinical Sciences and Community HealthTouro University California College of Osteopathic MedicineVallejo, CaliforniaChristopher Weber, MD, FAAP, FACP, CSCS, daBOM, FOMABariatric Services Medical Director, Ascension WisconsinObesity Medicine Director, Ascension Columbia St Mary's Bariatric CenterTrustee, Obesity Medicine AssociationAdjunct Assistant Professor of PediatricsMedical College of WisconsinMilwaukee, WisconsinLink to full program:https://bit.ly/4rG7QQp Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
My granddaughter suffers from menstrual cramps. Do you have any suggestions?Do you recommend nicotinamide daily to prevent recurrence of basal cell cancers?What works best to lower fibrinogen?I've been on Ozempic for a year and have diarrhea every morning!Is bypass surgery still being done?Would you recommend Bergamot for fatty liver?
Thanksgiving and overindulgenceA food poisoning incidentObservations on health at ThanksgivingWhat do you think of online sites offering prescriptions for hair loss via a questionnaire?
Dr. Erin Faules speaks with Dr. Damon Forbes about Lp(a), a genetically influenced lipoprotein linked to cardiovascular disease risk. They discuss how Lp(a) differs from LDL, its role in plaque and clotting, and why a one-time test can help clarify long-term risk. The conversation covers who to screen and when, interpreting Lp(a) alongside apoB and metabolic health, evidence-based ways to lower overall cardiovascular risk, and emerging Lp(a)-lowering therapies
In this solo episode, Darin reframes one of the most misunderstood forces in life — stress. Instead of seeing it as the enemy, he explores how stress is actually a messenger, guiding you back to alignment, safety, and awareness. Through science, spirituality, and lived experience, Darin breaks down how stress shows us where we're trying to control, where we're disconnected, and where our nervous system is calling for attention. He unpacks the layers of modern stress — from trauma and environment to community and purpose — and offers practical, embodied tools to restore calm, clarity, and resilience. What You'll Learn 00:00:00 – Welcome to Super Life: Solutions for a Healthier Life and Better World 00:00:32 – Sponsor Spotlight: TheraSauna - Natural Healing Technologies (15% off with code Darrandai) 00:02:10 – The Super Life Podcast: Finding Contentment, Happiness, and Purpose 00:02:51 – Today's Topic: Stress - Reframing Stress as an Ally and Dashboard Light 00:04:54 – The "No Choice" Universe: Reconnecting to Infinite Possibilities 00:05:16 – The Reality of Stress: Statistics and the Impact of Chronic Stress 00:06:21 – Stress is Layered: Beyond a Single Cause, Addressing Chronic Stress 00:08:29 – Solutions for a Super Life: Safety over Calm and the Vagal Response 00:09:38 – The Inner Dialogue Layer: Trauma, Unconsciousness, and Spiritual Bypassing 00:11:47 – The Social Field Layer: Relationships, Community, and Finding Your Way Home 00:14:20 – Sponsor Spotlight: Bite Toothpaste - Sustainable, Non-Toxic Tabs (20% off with code Darin20) 00:16:35 – Creating Your Own Vision: Setting Boundaries with Media and Social Algorithms 00:17:29 – Finding Your Purpose: From Raising Children to Healing Injuries 00:18:35 – Environmental and Existential Stress Layers: Clutter, Noise, and Service 00:19:26 – Stress Load and Resiliency: Why Small Triggers Cause Blow-Ups 00:20:02 – Understanding the Dashboard Light: Acknowledging Unwillingness 00:20:35 – Safety as the Signal: Body Relaxation and Providing Inner Security 00:23:44 – Reframing Trauma: Was it the Protector You Needed at the Time? 00:25:00 – Releasing Trauma: Techniques, The Healing Code, and Waking the Tiger 00:26:06 – Finishing the Survival Response: Shaking, Crying, Screaming, and Stretching 00:26:38 – Stress as a Multiplier: Impact on Immune System, Heart, and Aging 00:28:10 – Stress Slows Repair: Inflammation, Cardiovascular Risk, and Cellular Aging 00:29:48 – The Integrative Approach: Changing Your Environments to Support Anti-Stress 00:30:07 – Actionable Stress Solutions: Circadian Rhythm, Nature, and Noise Reduction 00:30:44 – Actionable Stress Solutions: Gratitude, Conscious Breath, and Movement 00:31:32 – Energy Drains to Eliminate: Conflict, Clutter, Scrolling, and Late Caffeine 00:32:17 – Connecting to Greater Purpose: The Super Life Patreon Platform 00:32:54 – Morning/Night Questions: Letting Go, Creating, and Contributing 00:33:17 – Final Toolkit: Slow Breathing, Movement, Nature, Sauna, and Sleep 00:34:25 – The Invitation: Digging into all Layers of a Super Life on Patreon Thank You to Our Sponsors Therasage: Go to www.therasage.com and use code DARIN at checkout for 15% off Bite Toothpaste: Go to trybite.com/DARIN20 or use code DARIN20 for 20% off your first order. Find More from Darin Olien: Instagram: @darinolien Podcast: SuperLife Podcast Website: superlife.com Book: Fatal Conveniences Key Takeaway "Stress isn't your enemy — it's your compass. Every wave of tension points you back to what's asking for care, attention, and love. When you stop fighting stress and start listening to it, you don't just survive — you evolve." Bibliography (selected, peer-reviewed) Sources: Gallup Global Emotions (2024); Gallup U.S. polling (2024); APA Stress in America (2023); Natarajan et al., Lancet Digital Health (2020); Orini et al., UK Biobank (2023); Martinez et al. (2022); Leiden University (2025). Cohen S, Tyrrell DA, Smith AP. Psychological stress and susceptibility to the common cold. N Engl J Med.1991;325(9):606–612. New England Journal of Medicine Cohen S, et al. Chronic stress, glucocorticoid receptor resistance, inflammation, and disease risk. Proc Natl Acad Sci USA. 2012;109(16):5995–5999. PNAS Kiecolt-Glaser JK, et al. Slowing of wound healing by psychological stress. Lancet. 1995;346(8984):1194–1196. The Lancet Kiecolt-Glaser JK, et al. Hostile marital interactions, proinflammatory cytokine production, and wound healing.Arch Gen Psychiatry. 2005;62(12):1377–1384. JAMA Network Tawakol A, et al. Relation between resting amygdalar activity and cardiovascular events. Lancet.2017;389(10071):834–845. The Lancet Epel ES, et al. Accelerated telomere shortening in response to life stress. Proc Natl Acad Sci USA.2004;101(49):17312–17315. PNAS McEwen BS, Stellar E. Stress and the individual: mechanisms leading to disease. Arch Intern Med.1993;153(18):2093–2101. PubMed McEwen BS, Wingfield JC. Allostasis and allostatic load. Ann N Y Acad Sci. 1998;840:33–44. PubMed Felitti VJ, et al. Relationship of childhood abuse and household dysfunction to many leading causes of death in adults (ACE Study). Am J Prev Med. 1998;14(4):245–258. AJP Mon Online Edmondson D, et al. PTSD and cardiovascular disease. Ann Behav Med. 2017;51(3):316–327. PMC Afari N, et al. Psychological trauma and functional somatic syndromes: a systematic review and meta-analysis.Psychosom Med. 2014;76(1):2–11. PMC Goyal M, et al. Meditation programs for psychological stress and well-being: a systematic review and meta-analysis. JAMA Intern Med. 2014;174(3):357–368. PMC Qiu Q, et al. Forest therapy: effects on blood pressure and salivary cortisol—a meta-analysis. Int J Environ Res Public Health. 2022;20(1):458. PMC Laukkanen T, et al. Sauna bathing and reduced fatal CVD and all-cause mortality. JAMA Intern Med.2015;175(4):542–548. JAMA Network Zureigat H, et al. Physical activity lowers CVD risk by reducing stress-related neural activity. J Am Coll Cardiol.2024;83(16):1532–1546. PMC Holt-Lunstad J, Smith TB, Layton JB. Social relationships and mortality risk: a meta-analytic review. PLoS Med.2010;7(7):e1000316. PMC Chen Y-R, Hung K-W. EMDR for PTSD: meta-analysis of RCTs. PLoS One. 2014;9(8):e103676. PLOS Hoppen TH, et al. Network/pairwise meta-analysis of PTSD psychotherapies—TF-CBT highest efficacy overall.Psychol Med. 2023;53(14):6360–6374. PubMed van der Kolk BA, et al. Yoga as an adjunctive treatment for PTSD: RCT. J Clin Psychiatry. 2014;75(6):e559–e565. PubMed Kelly U, et al. Trauma-center trauma-sensitive yoga vs CPT in women veterans: RCT. JAMA Netw Open.2023;6(11):e2342214. JAMA Network Bentley TGK, et al. Breathing practices for stress and anxiety reduction: components that matter. Behav Sci (Basel). 2023;13(9):756.
In this episode, Dr. Thomas Hemingway gets into the CARNIVORE diet, the Hype, the Positive, the Negative and the Data that exist, including the most Up-to-Date data and this may Surprise you as it is likely not what you've heard. Take a Listen and please Share with a Friend!*ACCESS my FREE workshop, "Younger, Stronger, for Longer!" How to turn back your biological age 10-20 years so you can do the things you want to do that you no longer thought possible due to your age. Perform at your best and live your best life!*And, in my new Performance, and Longevity medical practice we specialize in turning back your biological age and OPTIMIZING HORMONES so you can feel a decade or more younger so you can do the things you want to do that you thought were no longer possible due to your age. Join the waitlist here!SHARE with a Friend and please drop a Review:)*Don't wait to Prioritize your health, Start Today with the Simple and Powerful Steps detailed in my Best-selling book.*GET DIRECT ACCESS to DR. HEMINGWAY in these AMAZING COURSES!**Free resource: 'The truth about GLP-1s and their alternatives' - https://drthomashemingway.myflodesk.com/n1yyjkcb68Mahalo and Aloha andTo your health,
My guest is Alan Aragon, a renowned nutrition and fitness expert and researcher known for sharing the strongest evidence-based approaches to fat loss, muscle gain and overall health and fitness. We discuss how to optimize your protein intake, including how much to consume per meal and when, and the facts and myths about the “30-gram rule” and the “anabolic window” following exercise. We also discuss controversial topics such as seed oils, artificial sweeteners, animal vs. plant proteins, training fasted for fat loss and collagen supplementation. Alan Aragon clarifies the most important topics in nutrition and offers valuable time-saving yet extra-effective ways to exercise. He is a true expert in providing data-supported actionable exercise and nutrition protocols for anyone seeking to improve their body composition and health. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman Carbon: https://joincarbon.com/huberman Wealthfront**: https://wealthfront.com/huberman David: https://davidprotein.com/huberman Function: https://functionhealth.com/huberman **This experience may not be representative of the experience of other clients of Wealthfront, and there is no guarantee that all clients will have similar experiences. Cash Account is offered by Wealthfront Brokerage LLC, Member FINRA/SIPC. The Annual Percentage Yield (“APY”) on cash deposits as of December 27, 2024, is representative, subject to change, and requires no minimum. Funds in the Cash Account are swept to partner banks where they earn the variable APY. Promo terms and FDIC coverage conditions apply. Same-day withdrawal or instant payment transfers may be limited by destination institutions, daily transaction caps, and by participating entities such as Wells Fargo, the RTP® Network, and FedNow® Service. New Cash Account deposits are subject to a 2-4 day holding period before becoming available for transfer. Timestamps 00:00:00 Alan Aragon 00:02:17 Dietary Protein & Protein Synthesis Limits?, Tool: Post-Resistance Training & Protein Intake (30-50g) 00:09:16 Training Fasted, Post-Exercise Anabolic Window, Tool: Total Daily Protein 00:15:53 Daily Protein Intake, Timing & Exercise, Muscle Strength/Size 00:23:00 Sponsors: Carbon & Wealthfront 00:26:46 Does Fasted Training Increase Body Fat Loss?, Cardio, Individual Flexibility 00:36:53 Dietary Protein & Body Composition 00:38:58 Animal vs Plant Proteins (Whey, Soy, Pea, Quorn), Muscle Size & Strength 00:51:24 Sponsors: AG1 & David 00:54:14 Body Re-Composition, Gain Muscle While Losing Fat?, Tool: Protein Intake & Exercise 01:02:55 Fiber; Starchy Carbohydrates & Fat Loss, Ketogenic Diet 01:10:36 Inflammation, Fat & Macronutrients, Hyper-Palatability; Fish Oil Supplementation 01:16:52 Added Dietary Sugars, Sugar Cravings, Tool: Protein Intake 01:24:03 Artificial Sweeteners (Aspartame, Sucralose, Saccharine, Stevia), Diet Soda, Weight Loss 01:30:16 Sponsor: Function 01:32:04 Caffeine, Exercise & Fat Loss 01:34:53 Alcohol, Red Wine, Sleep, Lifestyle; Quitting Drinking & Stress Resilience 01:44:43 Seed Oils vs Animal Fats, Canola Oil, Olive Oil, Oil Production, Tool: Improve Diet Quality 01:55:50 Butter & Cardiovascular Risk, Saturated Fat, Mediterranean Keto Diet, Testosterone 02:00:43 Menstrual Cycle, Tool: Diet Breaks; Menopause Transition & Body Composition 02:07:04 Collagen Supplementation, Skin Appearance 02:12:44 Supplements: Multivitamins, Vitamin D3, Fish Oil, Creatine, Vitamin C 02:20:03 Resistance & Cardio Training, Tool: Cluster Sets & Super Sets 02:31:35 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, Sponsors, YouTube Feedback, Protocols Book, Social Media, Neural Network Newsletter Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices