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Leveling Up: Creating Everything From Nothing with Natalie Jill
Before menopause, our risk of heart disease is HALF what a man's is. Within a few years of our last period, it is EQUAL. By our seventies, it is HIGHER. So why is nobody screening us for it? This is the conversation midlife women have been waiting for. I sat down with Dr. Jayne Morgan, a research cardiologist and Vice President of Medical Affairs at Hello Heart, who is calling out menopause itself as the most missed opportunity in preventive cardiology. She is the creator of the Stairwell Chronicles, a science communicator who translates complex cardiology into kitchen-table language, and she has spent 25+ years researching what is actually happening to our hearts in midlife. This is our fourth cardiologist on the show. And she is different. She brings the research, the data, and a fierce honesty about why our healthcare system was built around the male body, and what we do about it now. WE GO DEEP ON: • Why menopause is a CARDIOVASCULAR event, not a gynecologic footnote • The half / equal / greater stat that every midlife woman needs to memorize • The 37-minute delay women face in the ER for cardiac care, and the exact phrase that gets you seen • Why hot flashes, night sweats, palpitations, and brain fog are cardiovascular signals, not just inconveniences • What estrogen actually does for your heart and what happens when it drops, and the 10-year HRT window • Her take on statins, the online backlash, and what the research actually says about LDL • What to do if you tried a statin and felt terrible — • Why it is LDL AND insulin resistance AND inflammation — not one versus the other • The labs to demand: ApoB, Lp(a), hs-CRP, fasting insulin, CAC scan • Why women were excluded from cardiovascular clinical trials until 1993, and how that built the entire field on the wrong data • The exact advocacy phrase that gets your concern documented in your chart • Three things you can do this week that actually move the needle This is not a doom episode. This is the conversation you bring to your doctor tomorrow. TIMESTAMPS: • 00:00 — Why menopause is a cardiovascular event • 12:00 — The symptoms women miss and the 37-minute ER delay • 26:00 — Estrogen, HRT and the 10-year window • 42:00 — LDL, cholesterol and the statin debate • 54:00 — What to test, what to track, what to demand • 66:00 — Health equity and self-advocacy • 76:00 — Three things this week Catch the full episode on YOUTUBE HERE: https://bit.ly/MidlifeConversationsYouTube Learn More About Dr. Jayne Morgan Instagram ➜ http://www.instagram.com/drjaynemorgan Website ➜ https://drjaynemorgan.com/ Hello Heart➜ https://www.helloheart.com/ Thank you to our show sponsors: LEELA QUANTUM: Get 10% off your first Leela Quantum order with the code NatalieJill at checkout at https://midlifeconversations.com/leela TIMELINE: Timeline is offering 20% off your order of Mitopure! Go to https://timeline.com/NATALIEJILL BIOPTIMIZERS: Stop settling for one form of magnesium when your body needs all 7. This one has them all! Get yours at https://bioptimizers.com/nataliejill and use code NATALIEJILL to save Free Gifts for being a listener of Midlife Conversations! Mastering the Midlife Midsection Guide: https://theflatbellyguide.com/ Age Optimizing and Supplement Guide: https://ageoptimizer.com Connect with me on social media! Instagram: www.Instagram.com/Nataliejllfit Facebook: www.Facebook.com/Nataliejillfit For advertising inquiries: https://www.category3.ca/ Disclaimer: Information provided in the Midlife Conversations podcast is for informational purposes only. This information is NOT intended as a substitute for the advice provided by your physician or other healthcare professional. Do not use the information provided in this podcast for diagnosing or treating a health problem or disease, or prescribing medication or other treatment. Always speak with your physician or other healthcare professional before making any changes to your current regimen. Information provided in this podcast and the use of any products or services related to this podcast does not create a client-patient relationship between you and the host of Midlife Conversations or you and any doctor or provider interviewed and featured on this show. Information and statements may have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent ANY disease. Advertising Disclosure: Some episodes of Midlife Conversations may be sponsored by products or services discussed during the show. The host may receive compensation for such advertisements or if you purchase products through affiliate links. Opinions expressed about products or services are those of the host and/or guests and do not necessarily reflect the views of any sponsor. Sponsorship does not imply endorsement of any product or service by healthcare professionals featured on this podcast.
Join Nicolas and Riley as they sit down with Ruth McCabe, Conservation Manager at Heartland Cooperative. They dive into the realities of agricultural conservation, why certain practices work in other countries but struggle in Iowa, the balance of economics and environment, and why there's no single scapegoat for water quality. hokseynativeseeds.com (for all your native seed, backyard prairie, hunting mixes, CRP mixes, native pasture mixes, and more) iowacovercrop.com (for all your cover crop mixes, waterway mixes, forage mixes, small grains, and more) MckayInsAgency.com (for all your financial planning and insurance needs)
This article is for educational purposes only and is not a substitute for individualized medical advice. Always talk to your own healthcare provider before changing your diet, supplements, or medications.Unlocking the Secrets of Ferritin: What Your Iron Levels Are Telling YouYour “normal” bloodwork might be hiding the real reason you're exhausted, foggy, and losing hairTL;DR: * Ferritin is your iron savings account — and most labs only flag it as “abnormal” once it's nearly empty. * A level of 14 or 22 ng/mL might get a “you're fine” from your doctor, but optimal energy, mood, cognition, and hair growth usually need ferritin closer to 70–100 ng/mL. * Low ferritin can come from menstrual blood loss, poor absorption (celiac disease, low stomach acid, H. pylori), or inflammation-driven hepcidin blocking iron uptake.* If you're fatigued, foggy, cold, or shedding hair, ask for a full iron panel — not just a ferritin number — and talk through the results with your doctor.There's an old Japanese proverb: “When the body speaks, the wise person listens. When the body whispers, the fool waits for it to scream.” In health diagnostics, one of the quietest whispers is your ferritin level. It's often overlooked, yet it can be the missing link behind exhaustion, hair loss, brain fog, or the frustrating experience of bloodwork that comes back “normal” while you still feel terrible.What Is Ferritin?Ferritin is your body's iron storage protein. Think of your iron levels like a financial setup: hemoglobin is your checking account, drawn on daily. Ferritin is your savings account, tapped only when things get tight. Under stress, your body will drain the savings account long before it lets the checking account — hemoglobin — run low. That's why you can have “normal” hemoglobin and still be iron-depleted. A low ferritin level means your reserves are running out, and that shows up as fatigue, brain fog, mood changes, and thinning hair.Normal vs. OptimalMost labs flag ferritin as “normal” above roughly 10–20 ng/mL. That threshold mostly means you're not in immediate danger — not that you're thriving. Levels associated with feeling genuinely well tend to run from 70 to 100 ng/mL. So if you've been told your ferritin of 14 or 22 is fine, but you still feel wiped out, you're not imagining it — you're just being measured against a bar set for avoiding crisis, not for feeling good.Why Your Ferritin Might Be Low* Menstrual blood loss. For many women, the cumulative loss over months and years outpaces dietary iron intake, slowly draining reserves.* Absorption issues. Even a solid iron intake doesn't help if it isn't absorbed. Silent celiac disease, low stomach acid, or an H. pylori infection can quietly block uptake for years.* Inhibitors and hepcidin. Coffee, tea, and dairy consumed close to meals can inhibit iron absorption. Separately, inflammation can push your liver to produce hepcidin, a hormone that shuts down iron uptake even when you're eating enough.Symptoms to WatchPersistent fatigue, thinning hair, feeling cold more easily than others, and brain fog are the classic signs. If two or more of these sound familiar, it's worth getting your ferritin checked specifically — not just assumed to be fine because your CBC looked normal.The Bigger PictureIron does far more than carry oxygen. It's involved in thyroid hormone conversion, dopamine production, mitochondrial energy synthesis, and hair follicle health. That means low ferritin can produce symptoms that look a lot like depression or hypothyroidism — even when your thyroid panel and mood screening come back clean.Taking Action* Review your bloodwork. Look specifically at ferritin. Anything under 70 ng/mL is worth a conversation with your doctor.* Ask for a full iron panel. Ferritin alone isn't the whole story — request serum iron, total iron binding capacity (TIBC), transferrin saturation, and CRP (to rule out inflammation skewing the picture).* Adjust absorption habits. Space coffee and tea away from meals, lean into iron-rich foods, and avoid taking calcium and iron supplements together.* Choose the right supplement, if needed. Ferrous sulfate is harsh on the gut for many people. Iron bisglycinate is gentler and pairs well with vitamin C for better absorption — but check with your provider before starting, especially if high ferritin is a concern.* Loop in a professional. This is especially important before making changes if you suspect elevated ferritin, since iron overload carries its own risks.Listening to Your Body's WhisperYour body is constantly sending signals. Ignored long enough, whispers become screams. Taking ferritin seriously — not just as a checkbox on a lab report, but as a meaningful marker — is one concrete way to catch a problem while it's still easy to fix.Final ThoughtsMonitoring and optimizing ferritin can meaningfully change how you feel day to day. It starts with a simple ask: get the right test, read the number in context, and act on what it's telling you. If you want a more personalized look at your own levels and symptoms, consider scheduling a comprehensive health session.Stay informed, stay healthy, and listen closely to what your body is telling you. Until next time, take care.References* Camaschella, C. (2015). Iron-deficiency anemia. New England Journal of Medicine.* WHO guidance on serum ferritin concentrations for the assessment of iron status.* Clinical literature on ferritin thresholds and symptomatic iron deficiency without anemia.* Hepcidin and inflammation's role in iron regulation — recent reviews in Blood and Haematologica. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit tripleplaydoc.substack.com/subscribe
Join Nicolas, Kent, and Riley on this Coffee Time Wednesday as they discuss the hidden impact of agricultural chemical drift on native oaks. The guys also explore the massive surge in native plant popularity and why people are choosing prairies over lawns. hokseynativeseeds.com (for all your native seed, backyard prairie, hunting mixes, CRP mixes, native pasture mixes, and more) BirdHunterSupply.com (for all your bird hunting supplies and dog hunting supplies)
This week, Dr. Joel Kahn explores important new research showing how elevated inflammation, measured by Interleukin-6 (IL-6), may dramatically increase cardiovascular risk in people with high Lipoprotein(a), or Lp(a). He explains why IL-6 is emerging as an important biomarker and reviews the other inflammation tests he routinely uses at the Kahn Center, including hs-CRP, MPO, Lp-PLA2, NT-proBNP, fibrinogen, ferritin, the sedimentation rate, and the white blood cell count. Dr. Kahn also discusses Lilly's newly approved oral weight loss medication, the ABCDEF framework for cardiovascular prevention, the growing evidence linking erectile dysfunction and sleep apnea to heart disease, new research on cannabis use and coronary artery plaque, and intriguing early findings on creatine's potential role in supporting the immune system and anti-tumor activity. Finally, thanks to this week's sponsor, the Fresh Pressed Olive Oil Club. Visit getfreshDrKahn.com to take advantage of their special introductory offer and experience the health benefits of fresh, polyphenol-rich olive oil.
Welcome back to our weekend Cabral HouseCall shows! This is where we answer our community's wellness, weight loss, and anti-aging questions to help people get back on track! Check out today's questions: Brent: Hello again, just thought of this and wanted to add some insight to the acid reflux problem, I didnt even think about it but I've been drinking water from a spring for many years now and after some time the water jugs I use start to get algae build up and I have to clean them. Point is algae is high pH and could be throwing off my stomach acid making matters worse, plus the algae feeds good and bad bacteria so I'm sure that didnt help while I was on the cbo protocol... also gonna run the parasite test because i didnt know you could get them from spring water. And gonna start adding lemon or lime to my meals and see of it helps. Again thank you for everything you do and I look forward to hearing your opinion. Trish: Hello Dr Cabral -- Can you please explain the difference of when to take your estrogen balance or estrogen support? I'm post-menopausal and estrogen dominant. I'm on your progesterone but thought I needed to take an estrogen supplement as well. Thank you! Jaimie: Thank you for giving us hope when others say there isn't a cure. My 11yr old son was diagnosed with severe Crohn's 6 months ago. No GI symptoms or food triggers or stomach pain. Presented with anal fissures, mouth sores and not growing. He was put on remicaid infusions and his calpractin went from 2500 to 59 in 5 months. CRP levels are normal now and he is gaining weight and growing. Dr doesn't believe in leaky gut or other deficiencies could be part of the issue when I asked about running other labs. What tests would you run if this was your child. I have a hard time accepting infusions are his only solution for the rest of his life. His body is fighting something and the remicaid is just masking the root issue. In addition to the toll it is taking on his liver amongst many other things. Anonymous: Hi Dr. Cabral - Is there a non-toxic or at least "less" toxic brand of tampons you can recommend? Thank you! Anonymous: Hi dr Cabral! Thank you for this show! I had my Dutch test done last year. It showed 24hr free cortisol just at the high marker and the metabolized cortisol low just below the normal range marker. My phase 2 estrogen metabolism methylation marker was also low at 1.6 while the beginning normal range marker is 2.5. Does this all point to a detox pathway issue? What would you suggest? My estrodial was also just below the normal range which surprised me since I have very heavy and painful periods, my practitioner at the time said it might have just been an off month, which I remember was a weird month since my period was actually very mild. That is disheartening since the test is so expensive. I know this test is a year ago, but I've always had these questions and results in my mind. Thanks! Thank you for tuning into today's Cabral HouseCall and be sure to check back tomorrow where we answer more of our community's questions! - - - Show Notes and Resources: StephenCabral.com/3809 - - - Get a FREE Copy of Dr. Cabral's Book: The Rain Barrel Effect - - - Join the Community & Get Your Questions Answered: CabralSupportGroup.com - - - Dr. Cabral's Most Popular At-Home Lab Tests: > Complete Minerals & Metals Test (Test for mineral imbalances & heavy metal toxicity) - - - > Complete Candida, Metabolic & Vitamins Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Complete Stress, Mood & Metabolism Test (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Complete Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Complete Omega-3 & Inflammation Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels) - - - Get Your Question Answered On An Upcoming HouseCall: StephenCabral.com/askcabral - - - Would You Take 30 Seconds To Rate & Review The Cabral Concept? The best way to help me spread our mission of true natural health is to pass on the good word, and I read and appreciate every review!
Jim and Chris welcome back returning guest Dr. Phillip Snider for a Q&A episode that plays a little differently than usual. Listener emails open a broader discussion of healthspan and lifespan, (including how wealth, genetics, and lifestyle factors shape longevity), retirement planning for longevity, and Dr. Snider’s recommendation for additional tests to help assess your health risks. (5:15) — George cautions that median longevity statistics are heavily influenced by wealth, genetics, and individual behavior, and shares CDC data showing life expectancy rises significantly once someone reaches age 65. (29:45) — A listener asks Dr. Snider to discuss the value of the cardiac calcium score in assessing longevity. She also asks about the science behind statins, including their effect on plaque stability and a possible link to reduced dementia risk. Show Notes: Dr. Snider’s list of recommended tests: CAC test (coronary artery calcium,) or heart scan – a noninvasive, low-dose CT scan that measures calcified plaque in your arteries to predict future heart attack risk. hsCRP (high-sensitivity C-reactive protein) – measures inflammation in the body related to cardiovascular disease risk. IL-6 (Interleukin-6) – elevated levels are associated with multiple conditions including cardiovascular disease, diabetes (insulin resistance), cancer, and autoimmune disorders. The sample has to be frozen before sending to the lab for processing, so it may need to be collected at a hospital lab or free-standing lab facility rather than at a doctor’s office. MPO (Myeloperoxidase) – measures an enzyme found in white blood cells (neutrophils and macrophages). It is a key biomarker of inflammation and oxidative stress. In the bloodstream, high MPO levels indicate that immune cells are actively attacking vessel walls, making it a powerful predictor of cardiovascular disease and plaque instability. Lp-PLA2 (lipoprotein-associated phospholipase A2) – measures a specialized inflammatory enzyme highly concentrated in unstable, rupture-prone fatty plaques within your arteries. Unlike general inflammatory markers (like hs-CRP), Lp-PLA2 is specifically localized to inflammation of blood vessels. The post Healthspan and Retirement Planning for Longevity with Dr. Snider: Q&A #2628 appeared first on The Retirement and IRA Show.
Kevin Kincaid, CEO of Knoxville Hospital and Clinics, joins Nicolas and Kent. Kevin shares about his time serving on a nuclear submarine during the Cold War and dives deep into the complexities of rural healthcare, hospital funding, and the future of medicine in America. hokseynativeseeds.com (for all your native seed, backyard prairie, hunting mixes, CRP mixes, native pasture mixes, and more) IowaCoverCrop.com (for all your cover crop mixes, small grain mixes, and more)
*Over 2 million acres have been accepted into the 2026 Conservation Reserve Program. *Texas enrolled 106,000 acres in the CRP. *The U.S. Small Business Administration is offering an enhanced guaranteed loan program for business in the food production chain. *There have been some good rains around the Texas High Plains in the last few weeks. *The deadline for the Farm Dog of the Year contest is coming up. *Investigations into the fertilizer industry continue. *Harvest season is underway in the Texas Coastal Bend. *Aural plaque may be found in your horses ears.
Join the Prairie Farm Podcast crew on a road trip as we dive into the origins and natural predators of invasive prairie weeds. Smooth Brome, Sericea Lespedeza, Canada Thistle, Queen Anne's Lace, and Wild Parsnip, and discover what keeps these prolific plants at bay in their native ranges. hokseynativeseeds.com (for all your native seed, backyard prairie, hunting mixes, CRP mixes, native pasture mixes, and more) MckayInsAgency.com (for all your financial planning and insurance needs) BirdHunterSupply.com (for all your bird hunting supplies and dog hunting supplies)
You were told your AMH is low, and maybe that IVF was your only option. Maybe you went through it, and it did not work. Maybe you already have one child and have been told this time is different. And some part of you has been wondering whether that number is really the whole story. Here is what most women are never told. AMH reflects egg quantity, not egg quality, and not your ability to conceive. It predicts how your ovaries respond to medication. It does not explain why a cycle failed, why embryos stopped developing, or why outcomes have not changed despite every protocol adjustment. In this episode, I walk through a real case. Her AMH was 0.27 ng/mL. She had a failed IVF cycle behind her and was navigating secondary infertility. One pattern that stood out was inflammation. Her hs-CRP was 1.3 mg/L, read as normal by conventional ranges but not optimal, and something was driving it. She conceived naturally, not because the number changed, but because the systems shaping egg development were finally looked at. This is not about avoiding IVF or chasing a better lab value. It is about reading what your body has already shown you, so your next decision is an informed one. CHAPTERS 00:00 What your AMH actually tells you, and what it does not 01:00 Why a failed IVF cycle can be more informative than the number 02:00 This was not unexplained, age, or bad luck 03:00 The patterns we see, inflammation, nutrient absorption, brain, and hormone signaling 04:00 Addressing systems in sequence, not a random checklist 05:00 What it looked like when the body started responding 06:00 Natural conception at AMH 0.27, and why the number was not the point 07:00 Pausing before the next cycle, readiness over urgency 07:30 The Functional Fertility Second Opinion WHAT YOUR CLINIC MISSED The companion guide walks through the patterns a standard fertility workup tends to miss, with the markers behind each one, so you can take it to your next appointment and ask the questions. Email hello@fabfertile.ca, subject line MISSED, and we will send you the guide. FUNCTIONAL FERTILITY SECOND OPINION A free 45-minute call where I review your bloodwork, your history, and your partner's results with you. You leave knowing what your biology has been telling you and what your next decision could be. Email hello@fabfertile.ca, subject line FERTILE, or book here: https://fabfertile.com/pages/book ABOUT THE HOST I'm Sarah Clark, founder of Fab Fertile and host of Get Pregnant Naturally, a podcast with over one million downloads. My functional fertility team works with couples navigating low AMH and failed IVF, reviewing functional lab results, gut microbiome, food sensitivity, vaginal microbiome, nutrigenomics, HTMA, DUTCH, toxin testing, and bloodwork alongside nervous system work, to help identify patterns that may not have been considered. We work alongside your medical team, not instead of them. Sarah Clark, founder of Fab Fertile, host of Get Pregnant Naturally (1M+ downloads), and author of Fabulously Fertile. If this episode helped, leave a review on Apple Podcasts. It is how other women find this work.
Join Nicolas and Kent as they sit down with Elizabeth and Loren Steele from Hamilton Native Outpost. They discuss the incredible nutritional benefits of prairie-raised beef, managing native grazing systems, and why diverse plant communities build healthier livestock and landscapes. hokseynativeseeds.com (for all your CRP mixes, native pasture mixes, native seed, backyard prairie, and more) BirdHunterSupply.com (for all your bird hunting supplies and all your bird dog supplies)
Join Nicolas, Kent, and Riley for this week's Coffee Time as they dive into the latest Farm Bill updates, extending CRP through 2031, and exciting new cost-share opportunities for prairie burning and grazing. Plus, the guys discuss America's billion-dollar littering problem and what it costs the USA. hokseynativeseeds.com (for all your native seed, CRP mixes, hunting habitat mixes, pollinator mixes, native pasture mixes and more) IowaCoverCrop.com (for all your cover crop, water mixes, and more) MckayInsAgency.com (for all your insurance and financial planning needs)
On this episode of The Wisconsin Sportsman, Pierce is joined by Tim Brown, AKA The Bearded Uplander to dive into the world of upland hunting and conservation! Time is an Iowa-native and diehard upland bird hunter who spends his falls traveling the country with his dogs in pursuit of birds. In this episode, the guys dive into the rise and fall of the CRP program and how that is impacting modern soil health, water quality, and wildlife habitat. Tim shares his thoughts on how to pick a gun dog, the importance of educating farmers and consumers about good land practice over maximizing every square foot of property, the importance of public lands and local conservation initiatives, how many roosters a farm really needs, and using hunting as a tool for conservation and community building. All that and more in this week's episode! Huge thanks to Tim for coming on the show! Be sure to go check out the awesome work he's doing over at thebeardeduplander.com, The Bearded Uplander YouTube Channel, and follow along with him @thebeardeduplander on social media Big thanks to our fantastic partners: Lone Wolf Custom Gear: www.lonewolfcustomgear.com onX Hunt: www.onxmaps.com Huntworth: www.huntworthgear.com Good Chance Fly Fishing: www.goodchanceflyfishing.com Wisconsin Backcountry Hunters & Anglers: www.backcountryhunters.org/wisconsin TAKE ACTION THROUGH BACKCOUNTRY HUNTERS & ANGLERS www.backcountryhunters.com/take_action Call the US Capitol Switchboard at (202) 224-3121 and ask to speak with your representative Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
Join Kent and Nicolas as they welcome Travis Hall, Associate Editor of Field & Stream, to discuss public land advocacy, the roadless rule, and why protecting our wild spaces requires active participation from hunters, anglers, and outdoor enthusiasts everywhere. hokseynativeseeds.com (for all your native seed, CRP mixes, backyard prairie, pollinator mixes, and hunting habitat)
Quail habitat is the whole story. Kyle Hedges and Frank Loncarich spent five years following bobwhite quail across the Midwest, and the data pointed at one thing over and over: disturbed ground grows birds. On this episode, host Nick Larson brings back Kyle Hedges and Frank Loncarich, two biologists who helped run one of the largest quail habitat studies in the region. From 2014 to 2018 they monitored 500 nests, radio-collared chicks, and even collared raccoons to see how predators move through cover. What came out of it is a genuinely hopeful finding: you can grow quail if you're deliberate about it. The number that anchors the conversation: 95% of their brood locations were in habitat that had been burned, grazed, or otherwise disturbed within the previous 12 months. Grassland managed with fire and cattle beat the old broken-up dairy-farm model on nest success, on survival, and on eggs per nest. The thick, idle CRP field that looks so birdy in January? The chicks can't get through it. Before the quail talk, Nick and the guys swap turkey-season stories and take on the old myth that turkeys are eating quail and grouse into decline. The short version: the timing doesn't add up, and it never did. It's a habitat problem wearing a predator's costume. Chapters: 0:00 - 95% of Broods: The Stat That Reframes Everything 2:19 - Turkey Season Recap and a Mid-Morning Tom 15:14 - Are Turkeys to Blame for Quail and Grouse? 21:57 - Inside the 5-Year Quail Study 25:40 - Usable Space and the Numbers on Nest Success 28:23 - Why Broods Live in Recently Disturbed Cover 31:18 - Prescribed Fire and Grazing at Landscape Scale 34:37 - Why Change Is Hard on Working Farms 36:35 - The Idle CRP Problem 38:40 - How Often to Disturb: Every 1, 2, or 3 Years 41:17 - One Farm for Quail, Turkeys, and Deer 42:10 - Cost Share and the Real Price of a Burn 45:26 - Building a Fire Culture and Burn Associations 46:52 - Native Grass Restoration Goes Mainstream 48:11 - Pollinator Plantings as Quail Habitat 50:08 - What Good Quail Cover Actually Looks Like 53:02 - Shrubby Escape Cover and the 10-20% Rule 54:16 - Eastern Red Cedar and When Woody Cover Helps 59:36 - Predators, Raccoons, and Why Grasslands Win Resources & Links: Land and Legacy: https://landandlegacy.tv/ Kyle Hedges: https://landandlegacy.tv/about/ Frank Loncarich: https://landandlegacy.tv/about/ How to conduct a prescribed burn for upland bird habitat (Project Upland): https://projectupland.com/hunting-conservation/how-to-conduct-a-prescribed-burn-for-upland-bird-habitat/ Support the show: The Birdshot Podcast is Presented By onX Hunt. Use code BSP20 to save 20% on your onX Hunt subscription. Use code BSP10 to save 10% at Meadow Creek Mounts. Use code BS10 to save 10% at Trulock Chokes. Follow the show: Instagram: @birdshot.podcast Website: https://BirdshotPodcast.com Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
Quail habitat is the whole story. Kyle Hedges and Frank Loncarich spent five years following bobwhite quail across the Midwest, and the data pointed at one thing over and over: disturbed ground grows birds. On this episode, host Nick Larson brings back Kyle Hedges and Frank Loncarich, two biologists who helped run one of the largest quail habitat studies in the region. From 2014 to 2018 they monitored 500 nests, radio-collared chicks, and even collared raccoons to see how predators move through cover. What came out of it is a genuinely hopeful finding: you can grow quail if you're deliberate about it. The number that anchors the conversation: 95% of their brood locations were in habitat that had been burned, grazed, or otherwise disturbed within the previous 12 months. Grassland managed with fire and cattle beat the old broken-up dairy-farm model on nest success, on survival, and on eggs per nest. The thick, idle CRP field that looks so birdy in January? The chicks can't get through it. Before the quail talk, Nick and the guys swap turkey-season stories and take on the old myth that turkeys are eating quail and grouse into decline. The short version: the timing doesn't add up, and it never did. It's a habitat problem wearing a predator's costume. Chapters: 0:00 - 95% of Broods: The Stat That Reframes Everything 2:19 - Turkey Season Recap and a Mid-Morning Tom 15:14 - Are Turkeys to Blame for Quail and Grouse? 21:57 - Inside the 5-Year Quail Study 25:40 - Usable Space and the Numbers on Nest Success 28:23 - Why Broods Live in Recently Disturbed Cover 31:18 - Prescribed Fire and Grazing at Landscape Scale 34:37 - Why Change Is Hard on Working Farms 36:35 - The Idle CRP Problem 38:40 - How Often to Disturb: Every 1, 2, or 3 Years 41:17 - One Farm for Quail, Turkeys, and Deer 42:10 - Cost Share and the Real Price of a Burn 45:26 - Building a Fire Culture and Burn Associations 46:52 - Native Grass Restoration Goes Mainstream 48:11 - Pollinator Plantings as Quail Habitat 50:08 - What Good Quail Cover Actually Looks Like 53:02 - Shrubby Escape Cover and the 10-20% Rule 54:16 - Eastern Red Cedar and When Woody Cover Helps 59:36 - Predators, Raccoons, and Why Grasslands Win Resources & Links: Land and Legacy: https://landandlegacy.tv/ Kyle Hedges: https://landandlegacy.tv/about/ Frank Loncarich: https://landandlegacy.tv/about/ How to conduct a prescribed burn for upland bird habitat (Project Upland): https://projectupland.com/hunting-conservation/how-to-conduct-a-prescribed-burn-for-upland-bird-habitat/ Support the show: The Birdshot Podcast is Presented By onX Hunt. Use code BSP20 to save 20% on your onX Hunt subscription. Use code BSP10 to save 10% at Meadow Creek Mounts. Use code BS10 to save 10% at Trulock Chokes. Follow the show: Instagram: @birdshot.podcast Website: https://BirdshotPodcast.com Learn more about your ad choices. Visit megaphone.fm/adchoices
Dr. Brandon Smith discusses research that examined feeding 10-12 lbs. of soy hulls per day with limited access to CRP hay to dry, pregnant cows.
Dr. Ron Ehrlich welcomes back Associate Professor Dr. Jim Parker to explore emerging paradigm shifts in healthcare, focusing primarily on women's reproductive and metabolic health. Dr. Parker applies Thomas Kuhn’s cycle of scientific revolutions to modern medicine, explaining how traditional systems are failing by treating symptoms rather than maintaining optimal physiology. The conversation spans the evolutionary roots of PCOS, the critical impact of maternal lifestyle ("the soil") on pregnancy outcomes ("the seed"), and a call to action for measuring fasting insulin over glucose to combat the global metabolic health crisis. ◉
You're not depressed. You're not in crisis. You're functioning, showing up, holding it all together. But something is still off, and you can't quite name it.This episode is for that person.Brandi and Dr. Desiree Caruso, ND sit down to break down the real biology behind low-grade mood dysregulation — the kind that doesn't show up in standard bloodwork but is absolutely happening in your body. We're talking about two specific functional mushrooms, lion's mane and reishi, and going straight into the mechanisms: the actual compounds, the actual pathways, and the actual research that explains why these mushrooms have a genuine relationship with how you feel.This is not a vibe episode. This is the science.We've been asked over and over again whether functional mushrooms can do something for mood, and if so, how. Today we answer that question properly. If you've ever walked out of a doctor's appointment feeling dismissed — told everything looks normal, maybe it's stress, maybe it's your age — this episode is what comes next.What you'll learn:Why mood is a physiological state, not just a feeling, and what that means for how you address itThe specific terpenoid compounds in lion's mane (hericenones) that can cross the blood-brain barrier and what they do once they get thereWhy BDNF is the mechanism most antidepressants are thought to work through, and how lion's mane stimulates it directlyHow 90% of your serotonin is produced in your gut, and exactly how lion's mane supports that pathwayThe three-directional approach lion's mane takes: blood-brain barrier, neuroinflammation, and gut-brain axis simultaneouslyWhat the HPA axis is, why chronic stress dysregulates it, and how reishi's ganoderic acids help restore the natural cortisol rhythmReishi's relationship with GABA, the brain's calming neurotransmitter, and why that explains the felt sense of settling downThe 2026 randomized controlled trial showing measurable reductions in anxiety, cortisol, and inflammation at 12 weeksHow disrupted sleep literally changes how your brain processes emotional information, and the two specific mechanisms reishi addresses to help with thatHow to self-diagnose which mushroom fits your experience right now, and what to track over four weeks to know whether it's workingResources Mentioned:Dr. Andrew Huberman episode on adenosine and coffee: https://www.hubermanlab.com/episode/using-caffeine-to-optimize-mental-and-physical-performanceVigna, L. et al. (2019). "Hericium erinaceus Improves Mood and Sleep Disorders in the Elderly." Journal of Medicinal Food, 22(5).Contato, A.G. & Conte-Junior, C.A. (2025). "Lion's Mane Mushroom (Hericium erinaceus): A Neuroprotective Fungus with Antioxidant, Anti-Inflammatory, and Antimicrobial Potential — A Narrative Review." Nutrients, 17(8), 1307.Frontiers in Nutrition (2025). "Benefits, side effects, and uses of Hericium erinaceus as a supplement: a systematic review." Frontiers in Nutrition, 12, 1641246.Ratto, D. et al. (2023). "Hericium erinaceus: Acute and Chronic Effects on Cognitive Function, Stress, and Mood in Young Adults." Nutrients, 15(22), 4842.Cui, X.Y. et al. (2012). "Extract of Ganoderma lucidum prolongs sleep time in rats." Journal of Ethnopharmacology / Pharmacology Biochemistry and Behavior. PMID: 22297086.Yong, V.K.J. et al. (2026). "A blend of medicinal mushrooms including Reishi reduces anxiety, cortisol and CRP in a 12-week randomized controlled trial." Brain and Behavior.Your Next Steps:Follow us on Instagram: https://www.instagram.com/eversiowellness/Shop Eversio Wellness and save 15% with code PODCAST15: https://www.eversiowellness.com/discount/PODCAST15?redirect=%2Fcollections%2Fall-productsTake our wellness quiz to find the right mushroom for you: https://www.eversiowellness.com/pages/take-our-quiz
304: Today I'm joined by Dr. Charlie Fagenholz to discuss frequency medicine, muscle testing, and the hidden factors that may be affecting our health. We explore the connection between emotional trauma and physical symptoms, how mold, parasites, glyphosate, and environmental toxins can impact the body, and why many people struggle to find answers through conventional approaches alone. We also dive into circadian rhythms, EMFs, gallbladder health, and the importance of getting back to the basics when it comes to healing. This is a fascinating conversation about root-cause health, modern environmental stressors, and the powerful connection between the mind and body. Topics Discussed: → Understanding frequency medicine and muscle testing → How emotional trauma can show up as physical symptoms → Mold, parasites, glyphosate, and other hidden health disruptors → The role of light, sleep, and circadian rhythms in healing → EMFs and the modern environmental challenges affecting health → Why gallbladder health matters more than most people realize → Simple health habits that have the biggest impact Sponsored By: → Our Place | Stop cooking with toxic cookware, and upgrade to Our Place today. Visit https://fromourplace.com/REALFOODOLOGY and use code REALFOODOLOGY for 10% off sitewide. With a hundred-day risk-free trial, free shipping and returns, you can experience this game-changing cookware with zero risk. → Function | Check your health the way I do with 160+ lab tests and access to scans through Function, all for only $365 a year. Learn more at https://functionhealth.com/REALFOODOLOGY and use code REALFOODOLOGY25 for a $25 credit. → Shopify | Start your business today with the industry's best business partner, Shopify, and start hearing “cha ching.” Sign up for your one-dollar-per-month trial today at https://shopify.com/realfoodology → Qualia | Take control of your cellular health today. Go to https://qualialife.com/realfoodology and save 15% to experience the science of feeling younger. → Clearstem | Discover the CLEARSTEM difference — Because CLEAR SKIN CHANGES EVERYTHING. Go to https://clearstem.com/realfoodology and use code REALFOODOLOGY at checkout for 15% off your first order. → Cowboy Colostrum | Get 25% Off Cowboy Colostrum with code REALFOODOLOGY at https://cowboycolostrum.com/realfoodology Timestamps: → 00:00:00 - Introduction → 00:02:45 - What Is Frequency Medicine? → 00:06:15 - How Dr. Charlie Discovered Muscle Testing → 00:08:50 - The Biggest Misconceptions About Chiropractic Care → 00:12:45 - Mold, Parasites, Glyphosate + Hidden Health Stressors → 00:16:45 - Why Symptoms Aren't Always What They Seem → 00:19:30 - The Connection Between Emotional Trauma + Physical Illness → 00:23:05 - Muscle Testing Demonstration → 00:25:30 - How Frequency Medicine Is Used In Practice → 00:29:00 - Why More People Are Turning To Root-Cause Medicine → 00:32:18 - Red Light Therapy, Lasers + Cellular Frequencies → 00:33:28 - Circadian Rhythms, Sleep + Morning Sunlight → 00:34:24 - Are EMFs, Glyphosate + Environmental Toxins Driving Disease? → 00:37:30 - Why Health Doesn't Have To Be Complicated → 00:39:00 - Why The Gallbladder Is So Important → 00:41:28 - Life After Gallbladder Removal → 00:42:12 - CRP, Inflammation + Psoriasis → 00:43:50 - Understanding EMFs + Modern Technology → 00:46:20 - How Concerned Should We Be About EMFs? → 00:49:40 - Powerful Patient Success Stories → 00:52:34 - Vaping, Cigarettes + Modern Toxins → 00:54:40 - The Health Basics Most People Overlook → 00:57:02 - Why Emotional Trauma Matters More Than We Think → 00:59:04 - Where To Find Dr. Charlie → 01:01:04 - Building An Online Health Community → 01:02:44 - OutroShow Links: → realfoodology.com Check Out: → Dr. Charlie's Website → Instagram - https://www.instagram.com/drcharliedc/ Check Out Courtney: → LEAVE US A VOICE MESSAGE → Check Out My new FREE Grocery Guide! → @realfoodology → www.realfoodology.com → My Immune Supplement by 2x4 → Air Dr Air Purifier → AquaTru Water Filter → EWG Tap Water Database Produced By: Drake Peterson Learn more about your ad choices. Visit megaphone.fm/adchoices
Heart disease is not only a man's disease. It is the number one killer of women, responsible for ten times more deaths than breast cancer. And yet most women have never had a real conversation about their cardiovascular risk, because the medical system was not built to catch it in them.Dr. Martha Gulati is the Director of Preventive Cardiology and Associate Director of the Barbra Streisand Women's Heart Center at Cedars-Sinai, Director of the Davis Women's Heart Center at Houston Methodist, and author of Saving Women's Hearts. Her own quote has become one of the most cited lines in women's cardiology: "Heart disease is the number one killer of women, but lack of awareness is a close second."This conversation goes into how the female heart develops disease differently, why women's symptoms get dismissed even when they use the words chest pain, and the pregnancy complications, hormonal history, and inflammatory conditions that quietly raise cardiovascular risk for decades before anything shows up on a standard panel.Join the most comprehensive *female-specific community for health and longevity optimization.* After over a decade dedicated to human performance and women's health, I created this space to share everything you need to know to optimize health and lifespan. Inside, you'll get access to exclusive protocols, live Q&As, the latest female longevity science, and a private, supportive community of like-minded women.https://kayla-barnes-lentz.circle.so/female-longevity-communityIf you're already paying attention to food, sleep, and overall health, cleaning products are another place where exposure adds up quickly. Branch Basics is a simple way to clean your home with fewer unnecessary ingredients and less clutter under the sink.https://branchbasics.com/KAYLA15 What we cover:How women's heart attack symptoms differ from men and why they still get dismissed in the ERWhy women wait longer, receive fewer tests, and are less likely to see a cardiologist when they arrive with chest painThe labs every woman should ask for, including LP(a), high-sensitivity CRP, and ApoB, with specific reference rangesWhy women get more cardiovascular benefit per minute of exercise than men, and what the exercise prescription actually looks likeMediterranean diet, hidden salt, sleep, and the lifestyle foundations that move the needleConnect with Kayla:Instagram: https://www.instagram.com/kaylabarnes/TikTok: https://www.tiktok.com/@femalelongevityTwitter:https://x.com/femalelongevityWebsite:https://www.kaylabarnes.com/Spotify:https://open.spotify.com/show/4OLWWn22RGB0argbRPvAaQ?si=8e91b3c9e0ce4054Apple:https://podcasts.apple.com/us/podcast/longevity-optimization-with-kayla-barnes-lentz/id1591130227Follow Her Female Protocol: https://www.protocol.kaylabarnes.comConnect with Dr. Marth Gulati:Website: https://www.drmarthagulati.com/Instagram: https://www.instagram.com/drmarthagulatiLinkedIn: https://www.linkedin.com/in/martha-gulati-9b410496/Her Book (Saving Women's Hearts): https://www.drmarthagulati.com/general-2 #WomensHealth #HeartDisease #WomensHeartHealth #Cardiology #FemaleLongevity #HeartHealth #LongevityPodcast #PreventiveCardiology #HeartDiseaseInWomen #WomensCardiology #LongevityOptimization #KaylaBarnesLentz #HeartHealthForWomen #FemaleHealth #MarthаGulati
Send us Fan MailIn this Journal Club episode, Daphna reviews a retrospective cohort study from Istanbul examining clinical, laboratory, and ultrasound factors associated with UTI in neonates hospitalized for unexplained hyperbilirubinemia. Among 96 term and near-term infants, 31% had culture-proven UTIs, a striking prevalence. Pathological renal ultrasound findings were independently associated with UTI, with affected neonates 4.6 times more likely to have a concurrent infection. Notably, standard laboratory markers including CRP and white blood cell count failed to distinguish UTI-positive from UTI-negative infants. The findings prompt a practical question: should urine culture be part of the routine workup for neonatal hyperbilirubinemia?----Renal ultrasonography findings are associated with urinary tract infection in neonates with asymptomatic hyperbilirubinemia. Sarı EE, Salihoğlu Ö.J Perinatol. 2026 Apr 13. doi: 10.1038/s41372-026-02686-x. Online ahead of print.PMID: 41975209Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.Enjoy!
Welcome back to our weekend Cabral HouseCall shows! This is where we answer our community's wellness, weight loss, and anti-aging questions to help people get back on track! Check out today's questions: Kay: Hi Dr. Cabral, Thanks for your very informative and interesting podcasts. How would you advise a post-menopausal 60 y.o family member if they tested low in ferritin (39.4 ng/mL)? I've read that this biomarker shows how much energy your body's cells have and low levels would result in symptoms like fatigue, low energy/easily tired and excessive hair shedding. This family member suffers from these symptoms. Other biomarkers revealed low AM cortisol and low LDL-C/ApoB ratio (1.1) and low basal metabolic rate of 1143 kcals/day. Although her TSH tested normal (1.3 uIU/mL), she's been on levothyroxine 75 mcg to manage hypothyroid. Her high-sensitivity CRP was not optimal at 1.49 mg/L and she has a family history of heart disease. What would you recommend for this family member? Thanks Earl: I am currently on 20 mg of lisinopril daily. Also, my GFR is 62. Would either of these be a concern when considering creatine? Alesi: Dr.Cabral, can you please explain Alpha-gal syndrom? Why does it happen, how to confirm it by testing and how would you approach it? Is it treatable? Thank you Peter: Hello, Dr.Cabral. I am an integrative health practitioner and would like to thank you for helping me understand the underlying causes of human imbalances. There is one thing that makes no sense to me though…regarding IgG testing, why would you recommend to test every year? Why doesn't suffice to test once and simply stay away from intolerant food items? Why would these intolerances change? Also, in my country there are IgG4 vs IgG1-3 testing options, what are the differences? Thank you very much for your time and knowledge you share with us. Dipali: Hi I want to start 7 days detox plan, I already did your minerals and heavy metal test, I got my results back. My question is I am taking berberine, oregano oil and magnesium citrate,( I am prediabetic my Hba1c is 6.2)do I need to stop before starting detox method. Thanks Thank you for tuning into today's Cabral HouseCall and be sure to check back tomorrow where we answer more of our community's questions! - - - Show Notes and Resources: StephenCabral.com/3774 - - - Get a FREE Copy of Dr. Cabral's Book: The Rain Barrel Effect - - - Join the Community & Get Your Questions Answered: CabralSupportGroup.com - - - Dr. Cabral's Most Popular At-Home Lab Tests: > Complete Minerals & Metals Test (Test for mineral imbalances & heavy metal toxicity) - - - > Complete Candida, Metabolic & Vitamins Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Complete Stress, Mood & Metabolism Test (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Complete Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Complete Omega-3 & Inflammation Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels) - - - Get Your Question Answered On An Upcoming HouseCall: StephenCabral.com/askcabral - - - Would You Take 30 Seconds To Rate & Review The Cabral Concept? The best way to help me spread our mission of true natural health is to pass on the good word, and I read and appreciate every review!
Think energy, digestion, and weight. In this episode, Nurse Doza breaks down berberine — the metabolism-supporting supplement that helps regulate blood sugar, support a healthy insulin response, and improve cholesterol (LDL, HDL, total). Discover why MSW Nutrition's Berberine Plus is 5x more absorbable in the gut, how to dose it morning and night, and why it works at the level of your gut microbiome. The berberine supplement your metabolism has been waiting for. Featured Partner: MSW Nutrition — Berberine Plus MSW Nutrition's Berberine Plus delivers dihydroberberine (DHB) — the bioactive, highly absorbable form of berberine sourced from Berberis aristata — so you get berberine's full metabolic benefits at a fraction of the dose, without the gut upset that comes from mega-dosing standard berberine. That enhanced absorption is exactly why it's the berberine supplement Nurse Doza reaches for to support blood sugar, digestion, and weight — as discussed in this episode.
Enhanced Games Debut in Las Vegas as the First Openly Drug-Enabled "Biohacker Olympics" The inaugural Enhanced Games took place in Las Vegas with more than 40 elite athletes competing openly while using performance-enhancing drugs, a $25 million prize pool, and a $1 million world record bonus on the table. Host Dave Asprey, who serves on the advisory board of the Enhanced Games, breaks down why this event is less a sports story than a cultural signal: enhancement has moved from underground to prime time, and the institutions that spent decades controlling that conversation through drug testing and bans watched it happen on a stage in Las Vegas. Dave explains why WADA has always existed to protect institutions rather than athletes, why bodily sovereignty is the real issue at the center of this debate, and what it means that even with full transparency about what every athlete was taking, the records didn't fall quite the way you'd expect. The Enhanced Games are the closest thing yet to a public beta test for extreme human enhancement, and the data it generates will matter far beyond sport. Sources: https://www.nytimes.com/athletic/7302319/2026/05/23/enhanced-games-athletes-world-records-doping-steroids/ https://www.npr.org/2026/05/24/nx-s1-5831252/enhanced-games-steroids-olympics-trump https://www.bbc.com/news/articles/cedpz1zqp8po https://www.wusf.org/2026-05-24/the-enhanced-games-are-sunday-heres-what-to-know-about-the-controversial-event Kyle Busch's Death Showed How Severe Pneumonia Can Rapidly Escalate Into Fatal Sepsis NASCAR driver Kyle Busch died after severe pneumonia progressed into sepsis, a condition most people hear about but few truly understand until it is too late. Host Dave Asprey breaks down the biology of what happens when the immune system stops containing an infection and starts attacking the body systemwide, why sepsis can escalate from manageable symptoms to a life-threatening emergency faster than most people expect, and why even someone with great biomarkers and a dialed-in health stack can be blindsided by an acute inflammatory crisis. The warning signs matter: worsening breathing, confusion, rapid decline, and a sense that something is badly wrong are emergency symptoms, not signals to wait and see. Longevity is not only about optimization rituals. It includes knowing when your biology is in crisis and acting before the window closes. Sources: https://www.cnn.com/2026/05/24/health/what-is-sepsis-kyle-busch-wellness https://www.cnn.com/2026/05/26/health/video/sepsis-kyle-busch-medical-care-lead-jake-tapper https://www.michiganmedicine.org/health-lab/nascar-stars-death-shows-how-sepsis-can-kill-anyone-if-not-caught https://www.huffpost.com/entry/what-is-sepsis-kyle-busch_l_6a15a9c1e4b0ddcc84641f34 Menin Loss in the Hypothalamus May Be a Central Switch That Accelerates Aging New research in mice found that a protein called Menin in the hypothalamus may function as a central coordinator of biological aging across the whole body. When Menin declined, aging accelerated. When researchers restored it in older mice, memory improved and lifespan increased. Host Dave Asprey explains why this finding challenges the dominant wear-and-tear model of aging, what it means that the hypothalamus may be running a coordinated aging program rather than simply accumulating damage over time, and why a control-room model of aging points toward fundamentally different intervention strategies than chasing downstream symptoms like fatigue and memory loss. The research connects aging to neuroinflammation, which has direct implications for how biohackers think about hypothalamic health right now. It is still animal research, but the mechanistic case is strong and the implications for longevity science are significant. Sources: https://www.sciencedaily.com/releases/2026/05/260524012959.htm https://www.news-medical.net/news/20230323/Menin-protein-protects-against-aging-and-cognitive-decline.aspx https://www.eurekalert.org/news-releases/982100 https://www.eurekalert.org/news-releases/1116021 IL-6 Blockade With Tocilizumab Showed Early Promise for Treatment-Resistant Depression A small pilot randomized trial tested tocilizumab, an anti-inflammatory drug that blocks IL-6 signaling, in people with difficult-to-treat depression and found remission rates of 54% versus 31% with placebo. Host Dave Asprey breaks down why this result reframes depression as an immune biology problem for a meaningful subset of patients rather than a purely neurochemical one, and why the same inflammatory pathway that drives joint destruction in rheumatoid arthritis is showing up in the brains of people who don't respond to antidepressants. The practical implication is not to seek out a biologic drug off-label. It is to recognize that persistent low mood, fatigue, and low resilience may warrant a deeper biological workup than standard screening provides, starting with IL-6, CRP, and a full inflammatory panel. The brain is downstream of the immune system more than most psychiatry has been willing to admit, and this trial is the clearest evidence yet of why that matters. Sources: https://www.bristol.ac.uk/news/2026/may/pilot-trial-suggests-anti.html https://www.eurekalert.org/news-releases/1128678 https://www.medicalxpress.com/news/2026-05-trial-anti-inflammatory-drug-difficult.html https://clinicaltrials.gov/ New Science Paper Says Intrinsic Human Lifespan May Be About 50% Heritable A paper published in Science argues that the genetic contribution to human lifespan is roughly 50% heritable, far higher than previous estimates, once researchers correct for deaths caused by accidents, infections, and external causes unrelated to aging biology. Host Dave Asprey explains why this finding is liberating rather than deterministic, what it means that genetics loads the dice on lifespan more than the mainstream has been willing to admit, and why personalized longevity strategy matters far more than generic population-level advice. Your genes load the dice but you still roll them. The study pushes the field toward genetic stratification and biomarker-based personalization, and it validates the core premise that the same intervention will not produce the same outcome in every person. Get your genetics tested and build your strategy from your own baseline, not from what worked for the average person in a study. Sources: https://www.science.org/doi/10.1126/science.adz1187 https://pubmed.ncbi.nlm.nih.gov/41610249/ https://www.nature.com/articles/d41586-026-00300-w https://www.eurekalert.org/news-releases/1113892 This episode is designed for biohackers, longevity seekers, and high-performance listeners who want mechanism-level clarity on human enhancement, acute inflammatory risk, neuroendocrine aging, immune-driven depression, and the genetics of lifespan. Host Dave Asprey connects emerging clinical research, real-world performance culture, and actionable optimization frameworks into a clear picture of where biology actually drives outcomes and where most people are still managing symptoms instead of finding the mechanism. New episodes every Tuesday, Thursday, Friday, and Sunday. Keywords: Enhanced Games biohacking, performance enhancement bodily autonomy, WADA elite sport doping, Kyle Busch sepsis death, pneumonia sepsis escalation, sepsis warning signs, Menin hypothalamus aging, brain aging master switch, neuroendocrine aging longevity, tocilizumab depression IL-6, inflammation treatment-resistant depression, immune biology mental health, lifespan heritability genetics, longevity genetics personalization, genetic stratification healthspan, biohacking news 2026, longevity research 2026, healthspan optimization, inflammation testing CRP IL-6 Thank you to our sponsors! - HeartMath | Go to https://www.heartmath.com/dave to save 15% off. - The One Device | Use code DAVE for $10 off at theonedevice.com/dave - iRestore | Reverse hair loss at www.irestore.com/DAVE and get exclusive savings on the iRestore Elite, use code DAVE Resources: • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Get My 2026 Biohacking Trends Report: https://daveasprey.com/2026-biohacking-trends-report/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 00:00 – Intro 00:38 – Story 1: Enhanced Games 01:49 – Story 2: Kyle Busch Death (Sepsis) 03:09 – Story 3: Menin Protein and Brain Aging 04:37 – Story 4: Inflammation and Depression 06:20 – Story 5: Lifespan Heritability 07:47 – Takeaway See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Registered dietitian nutritionist Leyla Muedin discusses the growing interest in biological age versus chronological age and explains that biological aging is modifiable through consistent lifestyle choices. She outlines common measurement tools and biomarkers, including epigenetic clocks (DNA methylation), telomere length, VO2 max, inflammatory markers, grip strength, and muscle mass, noting that genetics account for only about 25–40% of biological aging variation. Key interventions include regular aerobic and resistance exercise, protein-adequate nutrition to preserve muscle and prevent sarcopenia (with whey protein and leucine-rich foods noted), improved sleep, stress management, reducing processed foods and visceral fat, and lowering chronic inflammation (CRP, IL-6). She also reviews hormetic stressors such as sauna use and mentions red/near-infrared light and sun exposure without sunglasses. Leyla shares client examples showing biological age can worsen or improve, and encourages repeat testing after lifestyle changes.
In this conversation, Dr. Reza Ardalan sits down with Dr. Hugh Coyne, a London-based family medicine practitioner and the son of a pediatric dentist, who built Coyne Medical with his wife and clinical partner Dr. Lucy Coyne specifically to practice the kind of preventive medicine the NHS 10-minute appointment window does not allow. His training at Imperial College London and postgraduate work in obstetrics and gynecology, pediatric health, and sports medicine give him a panoramic view of the screening opportunities most dentists are sitting on without realizing it. Dr. Coyne walks through the short blood panel he would build into every dental practice: HbA1c for diabetes risk that directly changes wound healing and periodontal outcomes, highly sensitive CRP for the kind of cardiovascular inflammation a UK Biobank study of over 400,000 people linked to a 61% higher risk of cardiovascular death, vitamin D with the K2 pairing that keeps calcium out of arterial walls, renal function, and a full blood count. From there, Dr. Coyne and Dr. Ardalan move into the oral microbiome shift from pathogen elimination to ecosystem restoration, the role of P. gingivalis in rheumatoid arthritis through citrullinated protein antibodies, and the cardiometabolic markers most patients never get tested for, including apolipoprotein B and lipoprotein(a). The third act covers GLP-1 medications, the Gila monster origin story, the medieval cautionary tale of Sancho the Fat, and the dental-chair implications most patients will never volunteer on a health history form. In this Episode: The short blood panel any dental practice can start with: HbA1c, highly sensitive CRP, vitamin D, renal function, and a full blood count Why vitamin D supplementation without vitamin K2 may direct calcium into the wrong tissues, including arterial walls How a UK Biobank study of more than 400,000 people linked elevated hs-CRP to a 61% higher risk of cardiovascular death in patients otherwise considered well What the 87% of patients open to in-chair screening tells you about how to introduce blood testing in your practice without losing trust The rule of halves for blood pressure, and why a 158 reading caught on a second visit can be profoundly consequential for a patient's long-term survival How the oral microbiome model has shifted from pathogen elimination to ecosystem restoration, and what that changes about prevention Why P. gingivalis turns up in rheumatoid arthritis tissue, and how oral pathogens correlate with colorectal, pancreatic, and esophageal cancers The bachelor-party analogy for apolipoprotein B and lipoprotein(a), and why every dentist should know their own Lp(a) number What every dental practice needs to know before sedating a patient on a GLP-1 medication Dr. Hugh Coyne is a London-based GP and the co-founder, with his wife Dr. Lucy Coyne, of Coyne Medical, a family medicine practice focused on preventive care and the early detection of disease. Dr. Hugh Coyne trained at Imperial College London with postgraduate degrees in obstetrics and gynecology, pediatric health, and sports medicine, and is a featured speaker at the Wellness Dental Forum 2026. Find him on Instagram and TikTok at @drhughcoyne and the clinic at @coyne_medical. Want to go deeper on the oral–systemic connection? Dentistry & Whole-Body Health is a 3-part live CE series on reading the medical signals hiding in your patients' bloodwork — and knowing what to do with them. Session 1: Hidden Signals · Saturday, November 7, 2026 The bloodwork your patients already have, read through a dentist's lens. HbA1c, hs-CRP, vitamin D, CBC — and when to monitor, pause, or refer. Session 2: Cardiovascular Clues · Saturday, November 21, 2026 The lipid markers most panels skip (ApoB, Lp(a)) and the oral–heart connection behind them. Yes — this is the bachelor-party one. Session 3: The New Weight Loss Era · Saturday, December 5, 2026 What GLP-1s are quietly doing to how your patients eat, metabolize, and heal — and the chairside adjustments that come with it. All 3-hour sessions run 8 AM PT / 11 AM ET / 4 PM UK, with 30-day recording access if you can't make it live. 9 AGD-PACE-approved CE credits across the series. Nothing here asks you to become a doctor — it gives you the medical layer that's already shaping your outcomes. Enrollment opens soon: $1,497 → Or try a single session — $625 More details coming soon!
Send us Fan MailDeep-dive into a 2026 cardiology review paper claiming seed oils reduce inflammation, exposing misrepresentations of cited clinical trials, and detailing how oxidized Ω-6 fats trigger inflammation.Companion article: Click HERETOPICS DISCUSSED:Seed Oil Profiles: Typical seed oils like sunflower are high in linoleic acid (omega-6 PUFA), while canola is higher in monounsaturated fats and resembles olive oil.Review Paper Critique: The 2026 JACC review falsely claims sunflower oil reduce inflammation like olive oil, citing an RCT that showed benefits only for canola and olive.RCT Analysis: In Iranian women with metabolic issues, switching to canola or olive oil lowered CRP by increasing MUFA and decreasing PUFA intake; sunflower oil produced no change.CRP Biology: CRP responds to oxidized lipids and cellular damage patterns, rising with exercise or infection and marking oxidized Ω-6 metabolites in modern diets.Oxidized Lipids: Ω-6 fats in LDL and cardiolipin oxidize easily, generating 4-HNE, MDA, and other signals that trigger immune clearance, similar to bacterial threats.Sterile Inflammation: High dietary linoleic acid causes chronic immune activation without pathogens, potentially contributing to metabolic and cardiovascular issues.PRACTICAL TAKEAWAYS:Prioritize monounsaturated fats from olive or avocado oil over high-linoleic seed oils like standard sunflower or soybean for lower oxidative stress potential.Check labels for high-oleic versions of sunflower oil, which shift the profile toward monounsaturated fats.Evaluate nutrition claims by examining original studies and fatty acid compositions rather than accepting review summaries at face value.Support the showHealth Products by M&M Partners:AquaTru: Water filtration devices that remove microplastics, metals, bacteria, and more from your drinking water. Through link, $100 off AquaTru Carafe, Classic & Under Sink Units; $300 off Freestanding models.OmegaQuant: At-home blood testing to see fatty acid profiles, including omega-3 fatty acids. Use link to see options and support M&M.SiPhox Health: Comprehensive, cost-effective bloodwork from the comfort of home. Use code TRIKOMES for 20% off.KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime)SporesMD: Premium mushrooms products (gourmet mushrooms, nootropics, research). Use code 'nickjikomes' for 20% off.For all the ways you can support my efforts
A cardiologist who helped set national cholesterol and weight targets for 40 years now says those numbers can mislead. Richard M. Fleming, a physician specializing in cardiovascular and inflammatory disease, argues that weight loss on a GLP-1 does not automatically mean a patient is getting healthier, and that some patients who never lose a pound are already metabolically well. This episode is based on his article "GLP-1 agonists and weight loss: Treating the disease, not the number," published on KevinMD. You will hear why body mass index was never built to diagnose individuals, why inflammatory and thrombotic markers track disease more honestly than the scale, and how clinical trials from CAST to ACCORD have shown what happens when medicine treats the surrogate instead of the patient. He walks through which inflammation tests a primary care physician can run before, during, and after GLP-1 therapy, including high-sensitivity CRP, homocysteine, and fibrinogen. Hear why a 40-year insider says precision medicine requires precision measurement, not precision weighing. Partner with me on the KevinMD platform. With over three million monthly readers and half a million social media followers, I give you direct access to the doctors and patients who matter most. Whether you need a sponsored article, email campaign, video interview, or a spot right here on the podcast, I offer the trusted space your brand deserves to be heard. Let's work together to tell your story. PARTNER WITH KEVINMD → https://kevinmd.com/influencer SUBSCRIBE TO THE PODCAST → https://www.kevinmd.com/podcast RECOMMENDED BY KEVINMD → https://www.kevinmd.com/recommended
The Land Podcast - The Pursuit of Land Ownership and Investing
Welcome to the land podcast, a platform for people looking to educate themselves in the world of land ownership, land investing, staying up to date with current land trends in the Midwest, and hearing from industry experts and professionals. On today's episode, we are back in the studio with Koby Kuhnen. We discuss: Coby bought his first hunting farm at 27 years old. He started with public land frustration and a long-term goal. Living at home helped him save aggressively after college. He looked at farms for years before buying the right one. The farm was bigger than planned but priced right. He used an ag-focused lender who understood land. His first moves were food, low pressure, and sanctuary. A major timber harvest reshaped the farm's future. CRP income helped, but he learned not to rely on it fully. His biggest advice to young buyers: pull the trigger. And so much more! Thanks again for all of the support from our partners—none of this would've been possible without them! - Buck Land Funding: https://www.firstbankers.com/bucklandfunding -Hawke Optics | Use Code WHTL for 15% off: https://bit.ly/hawkeoptics_ -OnX: https://bit.ly/onX_Hunt -Painted Arrow: bit.ly/PaintedArrow - Latitude Outdoors: https://www.latitudeoutdoors.com/ - Whitetail Master Academy https://www.whitetailmasteracademy.com - Use code 'HOFER' to save 10% off at www.theprairiefarm.com - Massive potential tax savings: ASMLABS.Net
Show Notes: Lilly Minkove shares her background in brand and strategy consulting, focusing on retail, beauty, and wellness. She discusses her time at McKinsey, Tapestry, and Louis Vuitton, emphasizing her work in the luxury sector. Lilly explains her transition from the corporate world to running ArtLogica Group, a boutique consulting practice focused on customer insights. Introduction to HeraSphere Lilly talks about her interest in health and wellness, which eclipsed her work in retail and luxury. She recounts attending a longevity talk by Dr. Darshan Shah, which sparked her interest in tracking biomarkers and consumer insights. Lilly describes the inception of HeraSphere, a women's health newsletter translating healthcare innovations into plain English. She highlights the importance of women's health, especially for those in perimenopause or menopause, and how her consulting experience translates to this new focus. The Five Pillars of Health Lilly outlines the five pillars of health: exercise and muscle, sleep, nutrition, brain health, and connection. She emphasizes the importance of strength training, noting that muscle is an anti-aging metabolic organ. She discusses the benefits of muscle, including anti-inflammatory proteins, insulin resistance, and bone density protection. The Critical Role of Sleep Lilly explains the critical role of sleep in brain function, immune system, and overall health. She discusses the importance of regularity and quality of sleep, noting that even one night of sleep deprivation can significantly impact natural killer cell activity. Lilly shares tips for improving sleep quality, such as maintaining a consistent sleep schedule, avoiding alcohol, and using a sleep tracker. The conversation turns to the impact of stress and anxiety on sleep and the importance of winding down before bed. The Impact of Sugar on the Body Lilly highlights the negative effects of sugar on the body, including inflammation, cardiovascular disease, and diabetes. She explains the concept of glucose spikes and how eating fiber, protein, and fat before carbohydrates can reduce their impact. Lilly emphasizes the importance of a diverse diet, recommending consuming 30 different types of plants and vegetables weekly and highlights the challenges of hidden sugars in processed foods. Maintaining Brain Health Lilly discusses the significance of brain health, noting that the brain consumes 20% of daily calories and requires continuous stimulation. She shares her experience with learning a new skill, cardio dance, and how it improves muscle memory and cognitive function. Lilly explains the link between midlife decisions and cognitive outcomes, emphasizing the importance of lifestyle measures in preventing Alzheimer's. Lilly elaborates on the benefits of keeping the brain active through learning and new skills. Community and Health Connection Lilly highlights the importance of social connections for overall health, citing a Harvard study on the mortality risk of social isolation. She discusses the decline of extended family households and the need for intentional efforts to maintain social connections. Lilly emphasizes the role of small interactions with people in the community in reducing loneliness and improving well-being. Lilly discusses the benefits of having a support system and the impact of feeling less isolated on health outcomes. The Complexity of the Wellness Industry Lilly explains her dual objectives: sharing knowledge with consumers and using consumer insights to inform her consulting practice. She offers services to help brands distill what their customers want and convey value effectively. Lilly highlights the complexity of the wellness industry and her expertise in understanding the female consumer. Measuring Health KPIs Lilly outlines key health metrics, starting with blood pressure and hemoglobin A1C, which measure metabolic efficiency and cardiovascular risk. She discusses C-reactive protein (CRP) as an indicator of systemic inflammation and its association with various diseases. Lilly explains fasting insulin and LDL cholesterol, noting their importance in measuring insulin resistance and cardiovascular health. She highlights the importance of bone density and body composition, recommending DEXA scans for accurate measurement. A Focus on Longevity Lilly discusses VO2 max, a measure of cardiovascular capacity and longevity, and the challenges of obtaining accurate measurements. She mentions the use of fitness trackers to estimate VO2 max and the benefits of regular monitoring. Lilly shares her personal practice of conducting twice-yearly health panels to track biomarkers and ensure overall well-being. Timestamps: 02:47: Transition to Women's Health and HeraSphere 06:48: Key Health Pillars: Exercise and Muscle 13:57: Sleep and Its Importance 23:57: Nutrition and Sugar Impact 29:53: Brain Health and Lifelong Learning 36:20: Connection and Social Support 38:32: Lilly's Services and Consumer Insights 41:08: Key Performance Indicators (KPIs) for Health 47:04: Advanced Health Metrics and Longevity Links: HeraSphere newsletter: https://herasphere.beehiiv.com/ HeraSphere website: https://herasphere.beehiiv.com/p/herasphere-24-become-the-ceo-of-your-health Consulting practice website: https://artlogicagroup.com/ This episode on Umbrex: Unleashed is produced by Umbrex, which has a mission of connecting independent management consultants with one another, creating opportunities for members to meet, build relationships, and share lessons learned. Learn more at www.umbrex.com. *AI generated timestamps and show notes.
Text Dr. Lenz any feedback or questions The 2026 Cholesterol Revolution: PREVENT Scores, Hidden Risk Markers, and CAC ScansThe script explains how 2026 ACC/AHA guideline changes aim to make heart attacks more preventable by shifting from short-term “10-year risk” thinking to “lower for longer,” precision prevention, and primordial prevention starting earlier in life. It critiques the older Pooled Cohort Equations for underestimating risk in younger people and introduces the PREVENT equation, which adds 30-year risk plus kidney, metabolic, and social factors. It highlights lipoprotein(a) as a largely genetic once-in-a-lifetime test and hs-CRP as an inflammation marker, and emphasizes coronary artery calcium (CAC) scoring as a tiebreaker for statin decisions (0, 1–99, ≥100). Cases illustrate these tools, including tighter LDL goals (
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Mixed Evidence on Eggs and Heart Risk; Debunking Saturated Fat Myths and 'Making Tallow Great Again'; Saturated Fat vs. Seed Oils: What the Science Says; Low-Carb, High-Fat Diets Raise ApoB in Healthy People; Saturated Fat Increases Harmful Lipid Markers; Nutrition Builds Resilience: The SELFISH Framework; Cath Lab Cooking and Nutritional Intervention; Impact of Macronutrient Substitution on Heart Risk; Polyunsaturated Fats Reduce Heart Disease by 19%; Olive Oil and Whole Food Plant-Based Diet Comparison; Track ApoB and CRP, Not Just Cholesterol #HeartHealth #Cholesterol #LifestyleMedicine #HealthTalks
In this episode, I this episoe I discuss tree plantings. The philosophy behind if they're worht it? If the traditional approach of spray, burn, spray, plant 600 trees, and tubing is the most reliable approach or the approach of grass selective only herbicides with 1000 trees per acre with no tree tubes is more effective ecspcially as early successional habitat. I go into detail of my own tree planting for the family farm consisting of 5.5 acres of CRP with 622 trees per acres totalling up to 3421 trees total with 275 tree tubes. Tree plantings are nostalgic for conservationists and land owners alike, but the prep work that goes into a planting is no easy undertaking. I hope you enjoy this episode: if you have any questions for this topic or future topics please email:JKnox0623@gmail.comReal Estatehttps://www.basecampcountry.com/agent-jesse-knox/Jesse.Knox@basecampcountry.com
The Land Podcast - The Pursuit of Land Ownership and Investing
Welcome to the land podcast, a platform for people looking to educate themselves in the world of land ownership, land investing, staying up to date with current land trends in the Midwest, and hearing from industry experts and professionals. On today's episode, we are back in the studio with Steve Hanson. We discuss: Shed trespassing is becoming more organized. Social media helped identify the trespasser quickly. Trail cameras are changing trespassing enforcement. Many landowners view sheds as personal property. CRP rates have softened in recent years. CSP funding appears stronger in the new Farm Bill. Habitat-focused CRP projects can benefit both parties. Water quality is becoming a bigger conservation focus. Forestry incentives may become more important nationally. Iowa land prices appear stable after major growth years. And so much more! Thanks again for all of the support from our partners—none of this would've been possible without them! - Buck Land Funding: https://www.firstbankers.com/bucklandfunding -Hawke Optics | Use Code WHTL for 15% off: https://bit.ly/hawkeoptics_ -OnX: https://bit.ly/onX_Hunt -Painted Arrow: bit.ly/PaintedArrow - Latitude Outdoors: https://www.latitudeoutdoors.com/ - Whitetail Master Academy https://www.whitetailmasteracademy.com - Use code 'HOFER' to save 10% off at www.theprairiefarm.com - Massive potential tax savings: ASMLABS.Net
What do your annual lab markers mean and are you getting a thorough assessment of your health? In this podcast, Ali Miller RD, walks through 47 essential biomarkers in the Naturally Nourished Comprehensive Wellness Panel. You will learn about the status of your white blood cells and red blood cells, markers of chronic infection, anemia, and even indicators of parasite activity. Ali will unpack in detail a comprehensive metabolic panel so you understand the fasting glucose and dawn phenomenon connection, markers of liver and kidney health, and how to support detoxification as well as further assess function with GGT and uric acid. Beyond typical cholesterol markers and the ideal range, learn about the importance of ratios and other added markers such as homocysteine, ApoB, and CRP. Understand the blood sugar story connecting the dots of fasting glucose, fasting insulin, HgbA1C% and other ways to bring blood sugar levels into ideal range to support body fat burn. Learn about functional ranges of thyroid markers and food-as-medicine for iodine, selenium, and zinc. Links: The Naturally Nourished Comprehensive Wellness panel is just $295 and includes a customized lab review with a functional nutritionist. Use LAB25 to save $25 off now!
Allen Miller of Tower Rock Ranch in Mansfield, Washington was the 2023 NCBA Environmental Stewardship Award regional winner. His family has run cattle on the same Douglas County ground since 1883. Allen joins Tip to talk about blending the art and science of range management on a 15,000-acre operation reshaped by five major wildfires in just 14 years. Allen shares hard-earned lessons on rotational grazing, post-fire rest and deferment, the payoff of 125 miles of new fence, and how Sage Grouse Initiative water infrastructure and remote tank monitors have transformed cattle distribution across rocky, water-scarce country. The conversation closes with candid thoughts on riparian fencing, CRP's unintended consequences, the promise of virtual fence and GPS ear tags, and Allen's advice to the next generation of agency professionals: come in humbly, listen first, and learn alongside the ranchers you're trying to help. Music by Lewis Roise. Support for The Art of Range comes from RanchBot and the Western Extension Risk Management Education Center. Visit the episode page at artofrange.com for the transcript and links to resources mentioned in this interview.
The episode explains that inflammation is a necessary survival mechanism, with acute inflammation supporting healing, while chronic inflammation drives chronic disease. It outlines major contributors to chronic inflammation including visceral fat (with fasting insulin as a proxy for insulin resistance), poor sleep and sleep apnea, ultra-processed foods, sedentary behavior, overtraining, chronic psychological stress, poor oral health, gut dysbiosis/barrier issues, smoking, alcohol, pollution, autoimmune disease, and chronic infection. The host reviews biomarkers to discuss with a physician such as high-sensitivity CRP, ESR, ferritin, WBC and neutrophil-to-lymphocyte ratio, fasting insulin, ApoB, omega-3 index/omega-6:omega-3 ratio, and homocysteine. Chronic inflammation is linked to cardiovascular disease, depression/anhedonia, brain fog, autoimmune disease risk, cancer mechanisms, skin aging, erectile dysfunction, and chronic pain. Treatment focuses on lifestyle (notably treating sleep apnea, sleep optimization, fat loss, exercise, oral health, omega-3 intake, sauna, stress regulation, circadian rhythm), selected supplements (vitamin D if deficient, curcumin, boswellia, ginger, garlic, olive oil polyphenols, sulforaphane, magnesium/glycine, taurine, NAC, quercetin, probiotics, creatine), and brief discussion of drugs including GLP-1 agonists, colchicine, NSAIDs, corticosteroids, and biologics. Chronic inflammation https://www.ncbi.nlm.nih.gov/books/NBK493173/ C-reactive protein test https://medlineplus.gov/lab-tests/c-reactive-protein-crp-test/ ESR blood test https://medlineplus.gov/lab-tests/erythrocyte-sedimentation-rate-esr/ Ferritin blood test https://medlineplus.gov/lab-tests/ferritin-blood-test/ Homocysteine test https://medlineplus.gov/lab-tests/homocysteine-test/ ApoB test https://my.clevelandclinic.org/health/diagnostics/24992-apolipoprotein-b-test Insulin resistance https://www.ncbi.nlm.nih.gov/books/NBK507839/ Obstructive sleep apnea https://medlineplus.gov/ency/article/000811.htm CPAP therapy https://medlineplus.gov/ency/article/001916.htm Sleep hygiene https://www.cdc.gov/sleep/about_sleep/sleep_hygiene.html Physical activity guidelines https://www.cdc.gov/physical-activity-basics/guidelines/adults.html Ultra-processed foods https://pmc.ncbi.nlm.nih.gov/articles/PMC10831891/ Gum disease https://www.cdc.gov/oral-health/about/gum-periodontal-disease.html Gut microbiome https://www.nccih.nih.gov/health/gut-microbiome-what-you-need-to-know Fiber https://www.hsph.harvard.edu/nutritionsource/carbohydrates/fiber/ Autoimmune diseases https://medlineplus.gov/autoimmunediseases.html Inflammation and heart disease https://www.heart.org/en/health-topics/consumer-healthcare/what-is-cardiovascular-disease/inflammation-and-heart-disease Inflammation and depression https://pmc.ncbi.nlm.nih.gov/articles/PMC4566946/ Cancer and chronic inflammation https://www.cancer.gov/about-cancer/causes-prevention/risk/chronic-inflammation Omega-3 supplements https://www.nccih.nih.gov/health/omega3-supplements-what-you-need-to-know Show Notes 00:00 Welcome to the Hart2Heart Podcast 00:58 Inflammation Basics 01:24 Acute Versus Chronic 03:29 Chronic Disease Link 03:52 Visceral Fat Driver 06:06 Sleep And Apnea 12:33 Food And Movement 16:02 Stress And Oral Health 18:17 Gut And Fiber 21:17 Toxins Autoimmune Infection 26:05 Inflammation Biomarkers 27:13 Inflammation Blood Markers 28:37 Ferritin Iron Balance 30:07 Metabolic Cardio Labs 32:08 Omega 3 Index Insights 34:07 Homocysteine Risks 34:58 Why Inflammation Matters 41:07 Lifestyle Fixes 46:24 Supplement Options 54:36 Medication Overview 57:36 Final Takeaways The Hart2Heart podcast is hosted by family physician Dr. Michael Hart, who is dedicated to cutting through the noise and uncovering the most effective strategies for optimizing health, longevity, and peak performance. This podcast dives deep into evidence-based approaches to hormone balance, peptides, sleep optimization, nutrition, psychedelics, supplements, exercise protocols, leveraging sunlight, and de-prescribing pharmaceuticals — using medications only when absolutely necessary. Beyond health science, we explore the intersection of public health and politics, exposing how policy decisions shape our health landscape and what actionable steps people can take to reclaim control over their well-being. Guests range from out-of-the-box thinking physicians such as Dr. Casey Means (author of "Good Energy") and Dr. Roger Sehult (Medcram lectures) to public health experts such as Dr. Jay Bhattacharya (Director of the National Institutes of Health (NIH) and Dr. Marty Mckary (Commissioner of the Food and Drug Administration (FDA) and high-profile names such as Zuby and Mark Sisson (Primal Blueprint and Primal Kitchen). If you're ready to take control of your health and performance, this podcast is for you.We cut through the jargon and deliver practical, no-BS advice that you can implement in your daily life, empowering you to make positive changes for your well-being. Connect with Dr. Mike Hart Instagram: @drmikehart Twitter: @drmikehart Facebook: @drmikehart
FSA Communication from the County to D.C. 2026 Kansas Wheat Tour Diarrhea in Calves 00:01:05 – FSA Communication from the County to D.C.: The show starts off with David Schemm, Kansas Farm Service Agency state executive director, as he explains grassland CRP, livestock forage program and how communication happens between counties and the Capitol. Farmers.gov 00:12:05 – 2026 Kansas Wheat Tour: Romulo Lollato, K-State professor in agronomy and wheat production specialist, continues the show sharing insight from the 2026 Kansas Wheat Tour that is happening this week across Kansas. 00:23:05 – Diarrhea in Calves: Brad White, Bob Larson, Phillip Lancaster and Scott Fritz with the Beef Cattle Institute end the show with part of their Cattle Chat podcast where they discuss causes of diarrhea in calves. BCI Cattle Chat Podcast Bovine Science with BCI Podcast Email BCI at bci@ksu.edu Send comments, questions or requests for copies of past programs to ksrenews@ksu.edu. Agriculture Today is a daily program featuring Kansas State University agricultural specialists and other experts examining ag issues facing Kansas and the nation. It is hosted by Shelby Varner and distributed to radio stations throughout Kansas and as a daily podcast. K‑State Extension is a short name for the Kansas State University Cooperative Extension Service, a program designed to generate and distribute useful knowledge for the well‑being of Kansans. Supported by county, state, federal and private funds, the program has county Extension offices statewide. Its headquarters is on the K‑State campus in Manhattan. For more information, visit Extension.ksu.edu. K-State Extension is an equal opportunity provider and employer.
Conservation isn't just about habitat — it's about people, relationships, and showing up when decisions are being made.In this episode, host Dr. Mike Brasher sits down with Bill Cooksey, Partnerships Program Leader for the Tennessee Wildlife Federation, to talk about a career spent at the intersection of conservation, policy, industry, and grassroots advocacy. Bill brings decades of experience from Avery Outdoors, National Wildlife Federation, and now TWF, offering a unique perspective on how conservation decisions actually get made — and why personal relationships still matter more than emails, posts, or press releases.The conversation spans conservation advocacy, wildlife policy, changes in the hunting community, misinformation, and how sportsmen can still shape the future if they're willing to engage directly.In this episode, listeners will hear about:Bill Cooksey's path through the outdoor industry, conservation NGOs, and policyThe role of state wildlife federations and how they differ from national organizationsWhy conservation advocacy is ultimately about relationships and trust“Pick up the damn phone” — why real conversations still move the needleHow sportsmen influence policy at the state and federal levelsProtecting hunting rights through proactive engagementA landmark Tennessee case involving duck hunters and municipal restrictionsWhy misinformation spreads faster than science — and how to respond productivelyChanges in how hunters get information and engage with conservationThe decline of CRP, habitat loss, and consequences for duck populationsThe chronic underfunding of the U.S. Fish and Wildlife ServiceWhy engagement — not social media outrage — creates real impactPractical advice for contacting legislators and making your voice heardReasons for optimism about the future of waterfowl conservationThis episode is a reminder that conservation success still depends on individuals willing to speak up, build relationships, and advocate for the resources they care about.SPONSORS:Purina Pro Plan: The official performance dog food of Ducks UnlimitedWhether you're a seasoned hunter or just getting started, this episode is packed with valuable insights into the world of waterfowl hunting and conservation.Bird Dog Whiskey and Cocktails:Whether you're winding down with your best friend, or celebrating with your favorite crew, Bird Dog brings award-winning flavor to every moment. Enjoy responsibly.
Today, I'm thrilled to welcome Dr. Nasha Winters back to the show for part two of our powerful conversation. As a trailblazer in integrative oncology and a passionate advocate for the “metabolic terrain” approach to health, Dr. Winters brings both deep expertise and a truly holistic perspective to the complex world of cancer and longevity. In this episode, she doesn't just share concepts—she takes us into the heart of what it means to test, assess, and address our own health in real life, especially when we're facing major diagnoses and difficult decisions. Episode Timestamps: Welcome & Introduction to Longevity Podcast ... 00:00:00 Metabolic Terrain Concept & Mitochondrial Health ... 00:05:00 The Test, Assess, Address Framework ... 00:08:08 Readiness, Honest Audit, and Lifestyle Evaluation ... 00:08:43 The Ten Terrain Drops in Cancer & Health ... 00:14:09 Emotional Foundations for Healing ... 00:15:01 Essential Lab Markers and the “Trifecta” ... 00:16:52 Affordable, Early Detection Labs—CBC, CRP, LDH, ESR ... 00:17:32 Shift Work, Circadian Health, and Mitigating Strategies ... 00:29:11 Handling Overwhelm: Prioritizing Fundamentals ... 00:37:45 Prevention Myths: Sun, Meat, and Food Access ... 00:42:26 Home-Cooked Food & Community's Healing Power ... 00:51:16 Behaviors That Seem Healthy But Aren't (e.g., Excess Cardio) ... 00:54:55 Age-Specific Advice and Building Longevity ... 00:56:25 Cancer, Metabolic Flexibility, and Biomarker “Under Five” Rule ... 01:02:32 Integrative Oncology's Strengths & Misconceptions ... 01:08:48 Risks of Extreme Alternative or Mainstream Approaches ... 01:12:58 Post-2020: Changing Health Trends & Immune Patterns ... 01:17:03 Hope for the Future & Patient Empowerment ... 01:24:02 Our Amazing Sponsors: STEMREGEN by Stemregen - A daily formula designed to support your body's natural repair systems by helping release your own stem cells into circulation, supporting recovery, resilience, and whole-body renewal at the source. Visit stemregen.co/NAT15 and use code NAT15. https://stemregen.co/NAT15 Vampire Exosome by Young Goose - A next-generation serum packed with three trillion PRP-derived exosomes and RejuvNAD to support collagen production and skin renewal at the cellular level—helping results build over time instead of fading fast. Shop HERE and use code NAT10. Bioregulators by Nature's Marvels - targeted peptides designed to support cellular signaling and renewal across key systems like circadian rhythm, immune function, and vascular health as part of a foundational longevity stack; head to profound-health.com and use code NAT15 for 15% off your first order. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Dr. Bill Lawrence Episode
RURAL AMERICA UNDER PRESSURE: FARMING, HEALTH, POLITICS, AND THE FIGHT FOR LOCAL COMMUNITIES On this episode of Rural Route with Trent Loos, Casey Yager from Illinois joins the conversation for a powerful discussion about the growing challenges facing rural America. Trent and Casey break down major issues impacting farmers, ranchers, and small-town communities, including wildlife management, shrinking pasture land, government conservation programs, rising farming costs, and the future of agriculture in the Midwest. They examine how deer populations, turkey decline, and CRP land policies are changing the landscape in Illinois while questioning whether current conservation efforts are truly helping rural ecosystems. The conversation also dives into Chronic Wasting Disease in deer populations, political corruption, massive campaign spending, low voter turnout, and the deep divide between urban and rural America. Casey shares his frustration with political chaos and explains why he believes people should focus more on family, local communities, and personal responsibility instead of nonstop national outrage. Trent and Casey also discuss health concerns ranging from tick outbreaks and alpha-gal syndrome to the importance of minerals, iodine, and nutrition. Casey opens up about his personal health transformation after overcoming severe back pain through dietary changes centered on meat and water, while also discussing the role of animal fats, protein, and modern nutrition in long-term health. The episode closes with an inside look at the booming demand for fencing in Illinois as cattle producers convert cropland back to grassland, along with concerns about strict Illinois gun laws, child safety, and preserving rural values for the next generation.
Sleep and weight gain are directly connected. Poor sleep disrupts hormones, raises blood sugar, tanks testosterone and estrogen, causes fatty liver, and wrecks your gut. If you've been doing everything right and the scale won't move, your sleep could be the missing link. FEATURED PRODUCT Chill by MSW Nutrition is a powdered drink mix formulated to support your body's natural calming chemistry — exactly what's needed when chronic stress and cortisol overload are stealing your sleep. Featuring GABA, L-Theanine, myo-Inositol, Taurine, and Magnesium, Chill helps balance neurotransmitters, quiet the nervous system, and promote the deep, restorative sleep your hormones, metabolism, and weight depend on — all five mechanisms discussed in this episode.
This week's stories: *Mud Playgrounds Double Kids' Bacterial Diversity and Spike Immune Genes 30% Finland swapped rubber playground surfaces for natural soil and mud across eight kindergartens — and after just one month, kids in dirt had twice the bacterial species diversity on their skin and a 30% increase in expression of ten immune-related genes. Dave breaks down why your immune system requires microbial exposure to calibrate properly, what the hygiene hypothesis actually means for adults, and the dead-simple weekly habit that primes your innate immunity the same way. Sources: https://creators.yahoo.com/lifestyle/story/finland-replaced-artificial-playground-surfaces-with-natural-elements-like-mud-and-soil--and-the-results-surprised-even-researchers-184318556.html https://www.sciencedaily.com/releases/2026/04/mud-playground-immunity.htm *Mixing Exercise Types Cuts All-Cause Mortality Up to 40% in 170,000-Person Study A 30-year BMJ Medicine cohort study found that people who rotate at least three different types of exercise weekly see 19 to 40% lower all-cause mortality — and that benefit held independent of total training volume. Dave explains why variety is a distinct biological signal, not a motivation trick, and why grinding more of the same thing is leaving longevity gains on the table. Sources: https://bmjmedicine.bmj.com/content/early/2026/04/26/bmjmed-2025-001513 https://www.sciencedaily.com/releases/2026/04/260426012305.htm https://www.theguardian.com/society/2026/apr/26/exercise-diversity-mortality *Facial Aging Rate from Photos Predicts Cancer Survival Better Than Blood Biomarkers AI analysis of serial facial photos in 1,000+ cancer patients found that computed facial aging rate independently predicted five-year survival with a hazard ratio of 2.1 — outperforming CRP and other standard blood markers. Dave covers what the AI is actually reading in those photos, why your face is a more accurate biological ledger than most labs your doctor orders, and the free monthly habit that turns this into an early warning system. Sources: https://medicalxpress.com/news/2026-04-photos-reveal-faster-biological-aging.html https://www.nature.com/articles/s43587-026-00123-4 *Vibration Vest OsteoBoost Mimics Weight-Bearing Exercise to Rebuild Bone Density OsteoBoost raised $8M for a wearable vest delivering 30–50Hz vibrations to the spine and hips, triggering the same Wnt/β-catenin osteoblast pathway activated by mechanical loading — with early trials showing 2–5% bone mineral density gains in six months. Dave makes the case forwhy bone loss is one of the most underrated aging crises in the biohacking community, and who should be watching this category closely. Sources: https://longevity.technology/news/osteoboost-raises-8m-to-scale-bone-wearable/ https://www.crunchbase.com/organization/osteoboost *10+ States Advance Raw Milk Bills as H5N1 Hits 100+ Dairy Herds Legislation expanding raw milk access is moving in Arizona, Iowa, New Hampshire, and elsewhere — while the CDC flags H5N1 in over a hundred dairy herds with documented aerosol transmission concerns. Dave gives an honest read on where the freedom argument, the microbiome argument, and the current risk calculus actually stand in April 2026, and what more rigorous sourcing looks like right now. Sources: https://www.yahoo.com/news/articles/us-med--raw-milk-legislation-120124275.html https://www.cdc.gov/flu/avianflu/dairy.htm This episode is designed for biohackers, longevity seekers, and high-performance listeners who want mechanism-level clarity on immune priming, exercise science, biological age tracking, bone health, and real food risk assessment. Host Dave Asprey connects emerging clinical research, large-scale cohort data, and real-world protocols into actionable frameworks for extending healthspan and sharpening performance. New episodes every Tuesday, Thursday, Friday, and Sunday. Keywords: mud playground immune system microbiome, soil bacteria skin diversity, hygiene hypothesis biohacking, exercise variety longevity, BMJ exercise mortality study, mixed training lifespan, facial aging rate cancer survival, biological age face AI, facial photo biomarker longevity, OsteoBoost vibration vest bone density, whole body vibration osteoporosis, bone mineral density wearable, raw milk H5N1 bird flu, raw milk legislation 2026, raw dairy safety biohacking, biohacking news, longevity research 2026, Dave Asprey weekly roundup Thank you to our sponsors! - KILLSwitch | If you're ready for the best sleep of your life, order now at https://www.switchsupplements.com/and use code DAVE for 20% off - Puori | Go to Puori.com/DAVE or use code DAVE at checkout to get 32% off your Puori Fish Oil subscription. You save more than $18. - iRestore | Reverse hair loss at www.irestore.com/DAVE and get exclusive savings on the iRestore Elite, use code DAVE Resources: • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Get My 2026 Biohacking Trends Report: https://daveasprey.com/2026-biohacking-trends-report/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 00:00 – Intro 00:20 – Dirt & Immune Training 02:22 – Exercise Variety & Longevity 04:16 – Facial Aging as a Health Biomarker 05:47 – Bone Loss & Vibration Tech 07:31 – Raw Milk & H5N1 Risk 09:20 – The Wrapup See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Send us Fan MailDr. Lyubina Yankova, hospitalist at Yale, presents findings from a large retrospective multi-center analysis across 106 sites examining whether the combination of procalcitonin and C-reactive protein (CRP) can match or outperform the inflammatory marker combinations currently recommended by the 2021 AAP guidelines for risk-stratifying febrile infants between 8 and 60 days of age. She shares why this combination showed similar sensitivity but higher specificity for detecting invasive bacterial infections — meaning fewer false positives, fewer unnecessary lumbar punctures, and fewer unnecessary antibiotics. She also addresses the limitations of retrospective data, why preterm infants were excluded from this analysis and what future research in that population might look like, and what it would take for guideline committees to feel confident enough to incorporate this combination into routine practice.Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.Enjoy!
Credits: 0.25 AMA PRA Category 1 Credit™ CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-481 Overview: Expand your prevention toolkit with new recommendations for cardiovascular disease screening. Listen in as we discuss how high-sensitivity C-reactive protein (hs-CRP) can guide screening for ongoing inflammation in patients who are at risk, the evidence behind primary and secondary prevention applications, and key limitations to keep in mind when applying these recommendations in practice. Episode resource links: Mensah GA, Arnold N, Prabhu SD, Ridker PM, Welty FK. Inflammation and Cardiovascular Disease: 2025 ACC Scientific Statement: A Report of the American College of Cardiology. J Am Coll Cardiol. Guest: Alan M. Ehrlich, MD, FAAFP Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at FranklySpeaking@pri-med.com The views expressed in this podcast are those of Dr. Domino and his guests and do not necessarily reflect the views of Pri-Med.
Stress Is Quietly Wrecking Your MetabolismWhy Overstimulation Is Sabotaging Your Fat Loss, Hormones, and EnergyThe Thrive Forever Fit Show with Jay NixonYou are not just stressed.You are overstimulated.And your nervous system was never designed for the world you're living in right now.In this episode, Jay breaks down one of the most overlooked drivers of stalled fat loss, hormone disruption, poor sleep, and frustrating lab results: chronic stress from modern overstimulation.This is not about politics.This is not about sides.This is about biology.Your brain cannot tell the difference between a real physical threat and a screen-based emotional trigger.Your body responds the same way.Your nervous system was built for short bursts of stress.A predator.A survival event.A temporary threat.Stress would spike.Cortisol would rise.Adrenaline would increase.Then it would shut off.That was healthy stress.What we live in now is constant stimulation.Notifications.Breaking news.Social media comparison.Emails at night.Financial headlines.Endless scrolling.Your brain never powers down.And when your brain never powers down, your metabolism never feels safe.When stress is constant:• Cortisol stays elevated• Blood sugar stays elevated• Insulin stays elevated• Inflammation rises• Sleep quality drops• Thyroid output can slow• Sex hormones can downshiftAnd then you ask:“Why can't I lose weight?”Because your body does not prioritize fat loss when it feels unsafe.It prioritizes survival.Threatened bodies store energy.Even if you are physically sitting still, high-intensity content activates your nervous system.Heart rate shifts.Stress hormones rise.Inflammatory pathways activate.Stack that multiple times per day, over months and years, and you create a body that is constantly bracing.Braced bodies:• Don't recover well• Don't burn efficiently• Crave quick energy• Struggle to sleep deeplyAnd then we blame food.Chronic stress can influence:• Fasting glucose• Triglycerides• HDL• Abdominal fat storage• Thyroid conversion• Progesterone and testosterone levels• CRP and inflammatory markersYou can eat perfectly and still stall if stress remains high.That is how powerful this is.If your nervous system does not feel safe, your metabolism will not feel efficient.This is why some people see massive improvements simply by improving sleep, reducing stress exposure, or creating more recovery.The body finally receives the signal that it is safe.You cannot control the world.But you can control what you repeatedly allow into your nervous system.You are not just what you eat.You are what you repeatedly consume mentally and emotionally.Your metabolism listens to all of it.In this episode, Jay explains why you cannot out-eat or out-train chronic stress, and why true metabolic health requires nervous system regulation, not just calorie control.If you've been tired but wired, waking at 3am, craving sugar at night, or plateaued despite effort, this episode will change how you see stress forever.Because once you understand this, you stop chasing food solutions for stress-driven problems.And that's where real metabolic mastery begins.