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-- On the Show -- Caleb Ragland, Chairman of the American Soybean Association, joins us to discuss how Trump's tariffs are reshaping the soybean industry and the economic future of rural America -- An ICE agent shoots and kills U.S. citizen during a federal immigration operation in Minneapolis as Trump falsely claims self defense and blames the radical left -- Governor Tim Walz prepares the Minnesota National Guard after uncoordinated ICE raids kill a resident and escalate tensions between state authorities and federal agents -- A confrontation between Minnesota state power and federal ICE operations raises concerns about institutional breakdown as courts and political norms face direct strain -- Trump proposes raising the U.S. military budget to 1.5 trillion dollars while falsely claiming tariffs will pay for it and contradicting years of anti Pentagon rhetoric -- White House Press Secretary Karoline Leavitt makes incoherent and contradictory claims about U.S. control over Venezuela and openly entertains buying Greenland -- Health Secretary Robert F. Kennedy Jr. says Donald Trump has ordered obesity to end as new federal dietary guidelines reshape school meals military food and assistance programs -- On the Bonus Show: New reporting shows many patients regain weight after stopping GLP-1 drugs, raising questions about whether medical weight loss now requires lifelong treatment. Plus, Donald Trump says the United States could effectively run Venezuela for years, signaling an extraordinary expansion of U.S. control over another country's government and oil industry
No.1 Health Doctor Benjamin Bikman breaks down keto, insulin resistance, sugar addiction, and calorie counting, and the ONE test that predicts weight gain! Dr Benjamin Bikman is a metabolic scientist and researcher focused on the link between insulin resistance and chronic disease. He is Professor of Cell Biology at Brigham Young University and Co-founder of Insulin IQ. Follow Dr Benjamin: Instagram - https://bit.ly/3MGLKNH X - https://bit.ly/3N6hziZ Website - https://bit.ly/491iGI6 He explains: ◼️Why shrinking fat cells depends on lowering insulin, not eating less ◼️How ketones act as a brain fuel that kills hunger and boosts metabolism ◼️Why constant carb intake traps energy and makes willpower fail ◼️How GLP-1 drugs may worsen muscle loss and long-term metabolic health ◼️Why a fasting insulin test reveals problems years before diabetes [00:00] What Should People Focus on for 2026 When It Comes to Diet? [02:32] What Is Metabolism? [07:18] Why Calorie Counting Doesn't Work [09:57] Ketones and Fat Loss [22:37] How the Liver Decides What to Do With Fat [25:09] Is Keto Sustainable? [27:15] Could Keto Help With Eating Disorders and Sugar Addiction? [30:24] The Effects of Keto on the Heart [32:54] Should You Take Exogenous Ketones? [38:04] Is Keto Suitable for Women? [44:36] The Perfect Diet and Lifestyle for 2026 [51:12] Steve's Ketone Levels After a Keto Shot [57:04] Ads [58:40] Continuing the Perfect Lifestyle for 2026 [59:42] When Not to Do Keto [01:05:48] How Cancers Use Sugar for Energy [01:10:36] Are Vitamins and Supplements Contributing to Obesity? [01:21:19] Thoughts on Ozempic and GLP-1s [01:26:05] Ads [01:32:58] What's the Best Sweetener to Use? [01:34:57] Collagen Peptides [01:37:03] Creatine [01:38:06] How to Get Rid of Stubborn Fat for Good [01:45:23] How Stress Contributes to Weight Gain [01:49:31] Check Your Testosterone Levels [01:51:39] What Tests Can We Do at Home? [01:52:49] If You Could Have One Thing for Life, What Would It Be? The Diary Of A CEO: ◼️Join DOAC circle here - https://doaccircle.com/ ◼️Buy The Diary Of A CEO book here - https://smarturl.it/DOACbook ◼️The 1% Diary is back - limited time only: https://bit.ly/3YFbJbt ◼️The Diary Of A CEO Conversation Cards (Second Edition): https://g2ul0.app.link/f31dsUttKKb ◼️Get email updates - https://bit.ly/diary-of-a-ceo-yt ◼️Follow Steven - https://g2ul0.app.link/gnGqL4IsKKb Sponsors: Pipedrive - https://pipedrive.com/CEO Wispr - Get 14 days of Wispr Flow for free at https://wisprflow.ai/DOAC Ketone - https://ketone.com/STEVEN for 30% off your subscription order
From the BBC World Service: After a rocky 2025, many analysts expect a similarly unsettled 2026. Plus, a new study indicates faster weight gain after quitting GLP-1 drugs, and X has failed to meet a deadline to address explicit content generated by its AI chatbot Grok.
E & T are back this week talking about how they get into the holiday spirit, if a viral Turkey Trot prank is grounds for a breakup, servers flipping tables over terrible tips, the Diddy Documentary, Amy Schumer filing for divorce, and how Weight Watchers has caved to selling GLP-1s. The end of the episode features a Patreon Preview. Join the Patreon to support the show and get extra & ad free episodes here OR on Apple & Spotify Podcasts: https://www.patreon.com/twostandupgalsSubmit your questions here: Twostandupgals@gmail.comE & T GREECE TRIP! Crete, Greece (June 5th-11th, 2026): https://cretegreecewithericaandteresa.my.canva.site/ We only have a few spots left and may add another group for a different week! Fill out the form if you'd like to receive the info: https://forms.gle/bNcNaVpC81onJx8VAITALY TRIP! Oct 9th – Oct 17th, 2026 Venice, Florence, & Rome, ($100 discount until end of December) Itinerary & sign ups here: https://groups.goaheadtours.com/tours/erica-spera-vfsg2026Not interested in Greece or Italy? Take our Travel Survey here: https://forms.gle/mYY5Ss7szCowAj2u8Watch full episodes on our YouTube Channel Here: https://www.youtube.com/@TwoStandUpGalsPodcast
From the BBC World Service: After a rocky 2025, many analysts expect a similarly unsettled 2026. Plus, a new study indicates faster weight gain after quitting GLP-1 drugs, and X has failed to meet a deadline to address explicit content generated by its AI chatbot Grok.
View This Week's Show NotesStart Your 7-Day Trial to Mobility CoachJoin Our Free Weekly Newsletter: The AmbushWhat if the key to longevity isn't found in your heart, your brain, or your hormones — but in your muscle?In this episode of The Ready State Podcast, Dr. Gabrielle Lyon explains why skeletal muscle is the most overlooked organ in modern medicine and how its decline quietly drives aging, disease, and loss of independence. Drawing from her work in nutrition, geriatrics, and muscle-centric medicine, Lyon breaks down how strength training, protein intake, and daily movement protect metabolic health, resilience, and mental clarity as we age. From preventing sarcopenia to rethinking weight loss, GLP-1 drugs, and what it really means to age well, this conversation offers practical insights for anyone who wants to stay strong, capable, and useful for life. If you care about longevity, this episode reframes the conversation — starting with muscle!WHAT YOU'LL LEARN IN THIS EPISODE● Why cardiovascular disease, diabetes, obesity, and dementia often begin in skeletal muscle● What “muscle-centric medicine” means — and why it challenges modern healthcare● Why building muscle for longevity is the important thing you can do● How GLP-1 drugs could unintentionally accelerate muscle loss and sabotage longevity● Why body fat percentage misses the real metabolic problem● How resistance training protects the brain, joints, and metabolism● The protein framework Lyon uses in clinical practice● Why movement is the fastest path to physical and mental freedomTIMESTAMPS(00:00) - Dr. Gabrielle Lyon(01:20) - What Kind of Doctor Are You(06:45) - Muscle-Centric Medicine Explained(14:18) - Vitality Blueprint: $50 Off Plans(16:45) - Role of a Muscle-Centric Physician(19:15) - Muscle: The Organ of Longevity(24:04) - Muscle Mass and Dementia Prevention(27:10) - Fear of Resistance Training(29:55) - Concerns About Being Too Bulky(33:20) - LMNT(35:00) - Subscribe to the Podcast(32:50) - Importance of Healthy Muscle Mass(40:00) - Best Ways to Measure Health Aging(44:27) - Nutrition Insights(50:07) - Staying Forever Young(51:23) - Start Your Momentous Journey(53:20) - The Forever Strong Playbook Overview(54:15) - Understanding GLP-1s(57:47) - Muscle-Centric Strength Program Overview(59:35) - Expectations from The Forever Strong Playbook(1:00:25) - Dr. Lyon's addition to the Infinite Shelf(1:01:11) - Finding Dr. Gabrielle LyonHuge thanks to our sponsors, Vitality, Momentous, and LMNT.Connect with Dr. LyonWebsite | Instagram | YouTubePre-Order The Forever Strong PLAYBOOKOrder Forever Strong
What if weight loss didn't require starving, suffering, or starting over every January? What if your metabolism actually wanted to stay lean, your cravings quieted down, and your energy supported the life God's calling you to live? Today, I'm breaking down why extreme diets backfire, and the simple, proven habits that create lasting weight loss without burnout. Watch The Dr. Josh Axe Show every Monday & Thursday on YouTube: https://www.youtube.com/@drjoshaxe?sub_confirmation=1
Gary & Shannon break down the biggest political stories driving the day in SwampWatch, including competing narratives around the Minneapolis ICE shooting, Vice President J.D. Vance’s remarks on Venezuela, and Governor Newsom’s State of the State address. The hour also explores the growing sober-curious movement, why fewer people are drinking, and how GLP-1 drugs may be accelerating the shift. Plus, tech reporter Marc Saltzman joins live from a packed CES in Las Vegas with standout gadgets and trends.See omnystudio.com/listener for privacy information.
Host: Darryl S. Chutka, M.D. Guests: Tamim I. Rajjo, M.D., M.P.H.; Meera Shah, M.B., Ch.B. Using GLP-1 medications for weight loss has become extremely popular. Is this the latest fad in losing weight, or will these medications completely change our approach to managing obesity? They do appear to be very effective in promoting substantial weight loss. What is the history of these medications? Are there differences in the various GLP-1 medications available? What are the potential adverse effects of this drug class? This podcast is the first in a series of three on the GLP-1 medications prescribed for weight loss. The topic for this podcast is “Who Is a candidate for a GLP-1 Medication?” and my guests include Dr. Meera Shah and Dr. Tamim Rajjo, both from the Division of Endocrinology and Metabolism at the Mayo Clinic. Check out the series! Rx for Weight Loss: A Closer Look Series | Mayo Clinic School of Continuous Professional Development Connect with us and learn more here: https://ce.mayo.edu/online-education/content/mayo-clinic-podcasts
It's the most talked-about drug in a generation, but do we actually understand how it works? This week, we are joined by Dr. Alexandra Sowa, author of The Ozempic Revolution, to pull back the curtain on the GLP-1 phenomenon. We move past the Hollywood headlines to explore how these medications are fundamentally changing our understanding of biology, willpower, and chronic disease. Whether you are considering the medication, are already on it, or are a skeptic, Dr. Sowa's evidence-based approach offers a roadmap for navigating this new era of metabolic health. The biology of weight: Why it was never just "calories in, calories out." How GLP-1s work in the brain and gut to reset the body's "set point." The stigma of "the easy way out" and why we need to change the narrative around obesity. Dr. Sowa's "SoWell" approach: Integrating medication with nutrition and long-term metabolic health. What the future of medicine looks like in a world where obesity is treated as a hormonal condition. For more information on Dr. Alexandra Sowa go to: AlexdraSowamd Or to try any of her products go to: getsowell.com And to read Dr. Sowa's book: The Ozempic Revolution Follow Dr. Sowa on Instagram @alexandrasowamd Follow us on Instagram: @every.body.talks @jenngiamo @schully Subscribe to our YouTube channel! Don't forget to subscribe to the podcast for free wherever you're listening. Apple Podcasts Spotify Be sure to leave a 5 star rating! It really helps grow the show. If you like the show, telling a friend about it would be amazing!
Ashley Koff is a registered dietitian and author who spent 20 years discovering that weight and health aren't separate issues, they're connected through "weight health hormones." After her own struggles with restrictive eating despite doing everything "right," a functional medicine doctor helped her understand what was actually broken, and that was, her body's natural hormone function.In this episode, Ashley explains why GLP-1 medications like Ozempic work, who actually needs them, and the critical foundational work required to avoid devastating rebounds. She reveals why current dietary guidelines fail women, shares her free weight health hormone assessment, cuts through the seed oil controversy, and offers practical strategies for eating healthy on any budget.If you're confused about nutrition, frustrated that eating healthy isn't working, or curious about GLP-1 medications, this conversation provides the clarity you've been missing.Guest's socials + website:Instagram: @ashleykoffapprovedWebsite: https://thebetternutritionprogram.com/ Kayla's social + website:Instagram: https://www.instagram.com/kaylabarnes/TikTok: https://www.tiktok.com/@femalelongevityTwitter: https://x.com/femalelongevityWebsite: https://www.kaylabarnes.comSpotify: https://open.spotify.com/show/4OLWWn22RGB0argbRPvAaQApple: https://podcasts.apple.com/us/podcast/longevity-optimization-with-kayla-barnes-lentz/id1591130227Follow Her Female Protocol: https://www.protocol.kaylabarnes.comBecome a Member of Kayla's Female Longevity Membership: https://kayla-barnes-lentz.circle.so/checkout/become-a-member
Let's bring those generations closer together. Steiny is back to defend his seat. Can he beat newcomer Lindsey from Sales and take home the winner's robe? San Francisco is having a super flu season - Don't go to work sick, please! Vinnie is updating us on the world's oldest Twinkie. The first GLP-1 pill is launching in the US. What's the worst pain you've ever felt?
Hour 1: Is another Stranger Things episode dropping today? Let's talk about Conformity Gate. Plus, Sarah shares why Prince's Purple Rain was chosen for Eleven and Mike's final moment. Vinnie is reporting the weather in Caracas, apples live a shockingly long time, and Bugs Bunny was surprisingly educational. Plus, if you missed National take down your christmas tree down day - get to it! Hour 2: “Tron: Ares” is now streaming on Disney+. Ben Affleck and Matt Damon star in a new Netflix movie, premiering January 16th. A former NFL player is suing his ex-wife for talking about his two Coke cans, and the gang is divided. The Winter Olympics is coming, and our first phone call of 2026 is here! Stuff our kids do that make us say, “Oh, it's genetic!” Scott Budman is reporting on a new electric vehicle charger that might be a game changer for the future of EVs. Plus, Uber unveils their Robotaxi design at CES. (47:51) Hour 3: Let's bring those generations closer together. Steiny is back to defend his seat. Can he beat newcomer Lindsey from Sales and take home the winner's robe? San Francisco is having a super flu season - Don't go to work sick, please! Vinnie is updating us on the world's oldest Twinkie. The first GLP-1 pill is launching in the US. What's the worst pain you've ever felt? (1:29:16) Hour 4: We're thinking a little too much about Vinnie's moves, on and off screen. Mariah Carey is out, Taylor Swift is back on top of the charts. DJO is having a moment as well. Netflix is bringing Star Search back LIVE later this month. Jelly Roll, Sarah Michelle Gellar, and Crissy Teigan set to judge. Let's revisit some ridiculously wrong predictions from the 1950s. The kids aren't drinking in January or any other month. Time changes things: remember these luxury items? A listener calls in with a great idea for picking up chicks in the modern era. And, how old is that guy? (2:02:28)
In today's episode, we sit down with Dr. David Jockers to unpack the science behind intermittent fasting, metabolic flexibility, mitochondria, research bias, and why women need a more nuanced approach to fasting. We dive into blood sugar regulation, cortisol, growth hormone, GLP-1, autophagy, protein intake, feast-famine cycling, and how fasting can support fat loss, energy, gut health, and brain performance — when it's done the right way. If you've ever wondered whether fasting is good or bad for women (especially in perimenopause), this conversation will bring clarity, context, and actionable guidance you can use right away. *** CONNECT:
I don't think GLP-1 meds are the answer for everyone, but I also don't think they're the villain of the story. For many people they can be genuinely life-changing, when they're used with the right support. So this episode is for anyone who's made that decision (or is seriously considering it) and wants to do it safely, sustainably, and with as much information as possible. -I can't stop you from taking these medications, but I can help you be informed: what to ask, what to monitor, what to eat, and how to protect your muscle, gut, and long-term health along the way.Today's episode is all about one of the biggest health conversations happening right now: GLP-1 medications.I'm joined by Ashley Koff, RD, to give you the straight dope on what's really going on beneath the surface: why so many of us are struggling with food noise, why some people never reach that “80% full” feeling, and what it means when your metabolic switches (the appetite and satiety systems that should be working in the background) aren't firing properly.We break down GLP-1s, starting with what happens in an optimally functioning body: the roles of hormones like GLP-1, GIP, PYY and CCK, and how they influence hunger, fullness, blood sugar, and cravings. We also talk through what side effects might be telling you, what to monitor if you do choose medication, and whether supplements have a role — including the so-called “GLP-1 boosters” you'll see everywhere.Most importantly, this episode is for anyone who wants lasting fat loss and better metabolic health, with or without drugs.Ashley Koff is a registered dietitian and founder of the Better Nutrition Program, and she trains clinicians as course director for UC Irvine's Integrative & Functional Medicine Fellowship. She's also the author of the upcoming book ‘Your Best Shot'.
Stay Connected Beyond the Podcast Subscribe to our Substack to get episode updates, event announcements, wellness tips, and personal thoughts from Marnie and Stephanie delivered straight to your inbox. If you love the show and want to support what we're building, consider a paid subscription for $30 annually. Your support helps fund podcast production and allows us to continue bringing you meaningful, high-quality conversations. https://theartoflivingwell.substack.com/ As we step into 2026, the wellness world is evolving faster than ever. From hyper-personalized health data to longevity, cortisol testing, wearables, and digital detoxes, this episode explores what's truly shaping the future of health and how to navigate it without overwhelm. In this insightful episode of The Art of Living Well Podcast®, hosts Marnie Dachis Marmet and Stephanie May Potter break down the most important health and wellness trends emerging in 2026. They discuss how technology, AI, at-home testing, and recovery tools are changing the way we care for our bodies while emphasizing why human connection, coaching, and personalization matter more than ever. Through real-life examples, client stories, and honest conversation, they unpack what's helpful, what's hype, and how to apply these trends in a sustainable, realistic way so you can feel better, live longer, and protect your mental and physical well-being. What You'll Learn in This Episode: Why personalized, data-driven wellness is becoming the foundation of health in 2026 How wearables like Oura, Whoop, and Apple Watch are shaping sleep, recovery, and stress awareness The role of at-home lab testing, including cortisol testing, in understanding your body Where AI fits into wellness and why it can't replace human support and connection How accessibility to health tools is expanding and what that means for long-term care The growing focus on longevity, cellular health, and recovery, not just anti-aging Why digital detoxes and tech boundaries are becoming essential for mental health How community wellness, recovery spaces, and movement-based practices are replacing traditional social habits What women need to know about hormones, menopause, and personalized testing Why simplicity, awareness, and guidance matter more than chasing every new trend Noteworthy Quotes from the Episode: "2026 is really the year of personalized health. There isn't one solution that works for everyone." "Data can be incredibly powerful, but it still needs a human to help interpret what it means." "Wearables don't just show us numbers, they validate how our bodies already feel." "Longevity isn't about anti-aging. It's about staying strong, mobile, and energized for life." "Digital detox isn't about removing technology, it's about creating boundaries." "Wellness doesn't need to be complicated. Simplicity is often the most effective approach." Episode Breakdown with Timestamps: [00:00] – Trailer: Longevity, AI, supplements, GLP-1s & modern wellness challenges [01:04] – Hosts Introduction: Welcome to The Art of Living Well Podcast [01:50] – New Year Wellness Trends: Why 2026 health trends matter [02:37] – Personalized Wellness: Bio-individuality, data-driven health & accessibility [04:10] – AI vs Human Support: Where technology helps and where human care is essential [05:58] – Wearables & Health Data: Oura, Whoop, Apple Watch, sleep & stress awareness [10:25] – Cortisol & At-Home Testing: Understanding stress, burnout & daily rhythms [23:00] – Digital Detox & Longevity: Tech boundaries, mental health & aging well _____________________________ "We love supporting our health from the inside out with Redmond Real Salt and Relyte Electrolytes. From pure, unrefined salt to clean, science-backed hydration, Redmond helps you feel your best every day. Use code LIVINGWELL15 for 15% off your first order at redmond.life.com taste and feel the difference!" _____________________________ Join the Minneapolis Hiking Collective: https://web.facebook.com/groups/1368978181038556/ _______________________________ Follow & Connect: Follow The Art of Living Well Podcast® Instagram: https://www.instagram.com/theartofliving_well/ YouTube: https://www.youtube.com/@theartoflivingwellpodcast LinkedIn: https://www.linkedin.com/company/the-art-of-living-well-podcast/ TikTok: https://www.tiktok.com/@theartoflivingwel/ Spotify: https://open.spotify.com/show/4gym3jOPdSHwrpM1BmxyJz Apple Podcasts: https://podcasts.apple.com/us/podcast/the-art-of-living-well-podcast/id1482050468 Connect with your Hosts here: https://www.theartoflivingwell.us/about-us
Send us a textLosing weight after 40 can backfire if it's done the wrong way—and in this episode of the Strong By Design Podcast, we uncover why that matters more than ever. Coach Chris Wilson sits down with Dr. Ron Eccles to explore the growing role of peptides and GLP-based therapies in sustainable weight and fat loss. Dr. Eccles breaks down peptides in simple terms, explaining how gut hormones like GLP-1, GLP-2, and GIP influence hunger, metabolism, and body composition. Together, they discuss why weight loss alone doesn't equal better health—and how preserving muscle, protecting joints, and improving metabolic health must be part of the equation.The conversation also tackles America's declining health outcomes, the concept of the “bliss point” in eating behavior, and what truly happens after you reach your target weight. Dr. Eccles shares insights on emerging peptide technologies, common myths around GLPs, and why lifestyle factors like sleep, movement, and nutrition determine long-term success. You'll also hear real-world lessons from clinical practice, including differences between men and women and the key health metrics that actually matter. This episode is a must-listen for anyone curious about modern weight-loss solutions and how to approach them safely, intelligently, and with long-term health in mind. Time Stamps00:00 – Lose weight the wrong way: Hidden dangers for anyone over 4000:56 — Welcome to the Strong by Design podcast!02:20 – Join Coach Chris and special guest Dr. Ron Eccles03:11 – Dr. Ron's 4 pillars of life balance—and why health is a top priority05:06 – Peptides explained: What they are and how they work06:56 – Discover the peptide that started it all10:38 – GLP-1, GLP-2, and GIP: the gut peptides that silence hunger12:53 – Why losing weight isn't the same as building a better body14:48 - Discussion of the abysmal health outcomes in America16:59 – The concept of the “Bliss Point” explained19:06 – What comes next? 3 options after hitting your target21:02 – Next-level peptides: control appetite, burn fat, and save muscle26:50 – The future of peptides: No injections required29:12 – Debunking myths about GLPs33:30 – How chronic joint pain affected Dr. Eccles's wife36:33 – Weight loss differences between men and women37:56 – The 5 key metrics Dr. Eccles tracks with his clients39:18 – The science behind Alpha Shred revealed43:35 – Lifestyle factors that make peptides work47:02 – Why sleep is essential for brain health53:31 – Key advice before your peptide journey55:39 – Why some “unconventional” doctors get it right1:00:26 - Stay connected beyond the episode with Ron Eccles1:03:23 - Fun fact about the Strong by Design Podcast name1:05:23 - Please share and leave ratings & reviews for the SBD podcast! Resources:15-minute Consultation at 941-799-6583Connect with Dr Ron: InstagramStart the New Year with more Focus, Clarity & Mental Energy!Grab some Neuro-Thrive at a Discount - Use Code: SBD2026
You can go to my link https://aura.com/hammer to try 14 days for free. That's enough time for Aura to start scrubbing your personal info off these data broker sites, automatically #sponsored For this final post show of the year, the producers and I sit down to reflect on the updates from these guests, gossip some bts stuff about some of them, and kinda lose our minds lol: Watch here: ➡️ https://bit.ly/chpostshow
Happy New Year! To kick off 2026, Elizabeth welcomes registered dietitian and integrative nutrition expert Ashley Koff, RD, founder of The Better Nutrition Program and author of the forthcoming Your Best Shot: The Personalized System for Optimal Weight Health - GLP-1 Shot or Not. With over 25 years in the field, Ashley offers a grounded, science-backed perspective on the “weight health era,” especially the growing conversation around GLP-1 medications and metabolic hormones.In this episode, Ashley demystifies the hype around weight loss drugs and reveals why the real focus should be on your body's own “switch”, the weight health hormones that regulate hunger, satisfaction, and metabolism. She breaks down the importance of looking beyond the number on the scale, explaining why bone, muscle, and visceral fat composition matter so much more. Episodes Here Ashley: Your Best Shot: The Personalized System for Optimal Weight Health―GLP-1 Shot or Not | The Better Nutrition Program Mentioned: Pure Encapsulation Magnesium Gummies BIOptimizers Magnesium BreakthroughOrtho Molecular Reacted Magnesium Say Hi To Elizabeth and Purely Elizabeth: Website | Instagram
Today on The Gist Healthcare Podcast, the CDC scales back vaccine recommendations for children, the Trump Administration distributes new funding for rural healthcare, and a pill version of a leading GLP-1 drug enters the market. Those stories and more. Hosted on Acast. See acast.com/privacy for more information.
In diet culture, hormones are frequently blamed for everything from weight gain and fatigue to irregular periods and mood changes. Scroll long enough and you'll find promises to “balance your hormones” through food rules, cleanses, or cutting out entire macronutrients. But what actually supports hormone health, and what's just another diet in disguise? In this episode, Matt sits down with endocrinologist Dr. Gregory Dodell for a grounded conversation on hormone health, GLP-1 medications and how to approach endocrinology through a non-diet lens. Want to support the show and get bonus episodes? Join our Patreon! https://www.patreon.com/nutritionformortalsLeave us a voicemail that may be featured on a future episode! Call us at (562)-N4M-POD1 (562-646-7631). We've got MERCH! Check it out HEREDon't want to miss any episodes in the future? Make sure to subscribe wherever you listen to podcasts!Where to find Dr. Dodell:IG: everything_endocrinePractice: www.centralparkendocrinology.comFor feedback or to suggest a show topic email us at nutritionformortals@gmail.comFeel free to contact our real, live nutrition counseling practice**This podcast is for information purposes only, is not a substitute for individual medical or mental health advice, and does not constitute a patient-provider relationship**
Try Calocurb natural appetite control (40% fewer cravings and 30% less hunger). It's prescription free, affordable, and fast acting. Get 10% off:https://witsandweights.com/calocurb--Can you lose fat without all the hunger?Maybe you're eating fewer calories than ever but somehow hungrier than ever, and it feels like a vicious cycle that prevents you from losing weight or stalls out your metabolism.Discover the satiety hierarchy that explains why some foods keep you full for hours while others leave you raiding the pantry within minutes. Learn the specific protein and fiber targets that suppress appetite at the hormonal level by triggering GLP-1 and PYY release, plus evidence-based meal timing strategies that can cut evening cravings in half. Philip shares 4 practical (and natural) appetite control tools that work with your body's natural hunger signals.This is 2 of our 8-part Appetite Series, and it's all about making fat loss feel less like a fight. Whether you're focused on body recomposition, building muscle while losing fat, or just trying to stick to your nutrition plan without white-knuckling through every meal, you'll walk away with tips to manage hunger naturally.Plus, stay until the end for a pre-meal protocol that can reduce calorie intake by nearly 20% and takes just 30 seconds to implement!Timestamps0:00 - Why managing hunger matters more than hitting your macros 2:53 - The satiety hierarchy 7:28 - Energy density strategies to eat more food on fewer calories 12:10 - How to activate natural GLP-1 and satiety signals 14:02 - Front-loading calories and why breakfast size affects evening cravings 19:54 - 4 natural appetite tools 24:22 - Connecting satiety strategies to strength training and body recomp 27:18 - Bonus: 30-second pre-meal protocol to reduce calorie intake by 20%Support the show
The Bald and the Beautiful with Trixie Mattel and Katya Zamo
'Twas 12 days after Christmas, when we gathered in the valley, To record a podcast and reflect on our holiday glee. We had dashed through L.A., to a glittering A-List soirée, To eat pizza and sliders at Charlize Theron's chalet. Trixie ran into Paul Feig, a multi-Emmy nominee, But congratulated him, instead, on a bit part from the 90s. Such awkwardness made her hungry, so she eyed the pizza pie, But Sofia Vergara blocked the way, and she couldn't get by. Instead of battling the gorgeousness, she took a circuitous route, Dodging Vergara's radiance and a tray of Brussels sprouts. As the dolls danced and grew tired, they eventually went home, But still full of cheer, Katya whipped out her phone. And lo, on Grindr, there appeared a man with looks and class, An absolute winner, with an immaculate ass. Katya ate so much butt that the next day alas, Her tongue grew sore, her lips chapped like broken glass. But excess is allowed, so they have no regrets, This was a holiday season they shall not soon forget. So as 2026 begins, we want everyone to hear: Happy Holidays to all, and to all a Wonderful New Year! You're going to love Hungryroot as much as we do! For a limited time get 40% off your first box PLUS get a free item in every box for life by using code BALD at: https://Hungryroot.com/BALD This episode is sponsored by BetterHelp. BetterHelp makes it easy to get matched online with a qualified therapist! Sign up today and get 10% off at: https://BetterHelp.com/BALD To see if your insurance covers GLP-1s, get your free insurance check at: https://Ro.co/BALD Follow Trixie: @TrixieMattel Follow Katya: @Katya_Zamo To watch the podcast on YouTube: http://bit.ly/TrixieKatyaYT To check out our official YouTube Clips Channel: https://bit.ly/TrixieAndKatyaClipYT Don't forget to follow the podcast for free wherever you're listening or by using this link: https://bit.ly/thebaldandthebeautifulpodcast If you want to support the show, and get all the episodes ad-free go to: https://thebaldandthebeautiful.supercast.com To check out future Live Podcast Shows, go to: https://trixieandkatya.com/#tour To check out the Trixie Motel in Palm Springs, CA: https://www.trixiemotel.com Listen and Watch Anywhere! http://bit.ly/thebaldandthebeautifulpodcast Follow Trixie: Official Website: https://www.trixiemattel.com TikTok: https://www.tiktok.com/@trixie Facebook: https://www.facebook.com/trixiemattel Instagram: https://www.instagram.com/trixiemattel Twitter (X): https://twitter.com/trixiemattel Follow Katya: Official Website: https://www.welovekatya.com TikTok: https://www.tiktok.com/@katya_zamo Facebook: https://www.facebook.com/welovekatya Instagram: https://www.instagram.com/katya_zamo Twitter (X): https://twitter.com/katya_zamo #TrixieMattel #KatyaZamo #BaldBeautiful Learn more about your ad choices. Visit podcastchoices.com/adchoices
The holidays are over, but here's something to celebrate... JUST TRISH is back! We catch up on the INSANE New Year's Eve halter-top drama after Tara Lynn faced severe backlash. Plus, Bop House co-founder Camilla Araujo gets called a scammer over her EXPENSIVE influencer course. And Trisha shares her most exciting announcement yet: She's running for office.
Ready for a judgment-free conversation about GLP-1 agonists and what they can truly offer midlife women seeking better energy, metabolic health, and longevity? In this podcast, hormone and nutrition expert Ashley Koff joins me to break down the noise and misinformation around GLP-1s, reframing them as one possible tool—not a magic fix—within a much bigger picture of whole-body health. Ashley shares how to advocate for yourself as an empowered patient, ask better questions, and partner more effectively with your healthcare provider with confidence. We also dive into why nutrition and lifestyle are essential foundations for optimizing hormones, whether you're using GLP-1s or not. Most importantly, we emphasize listening to your body and making informed choices that support long-term vitality. If you're curious about GLP-1s and want clear, compassionate guidance for midlife health, this is a must-listen episode! Ashley Koff, RD Ashley Koff is the founder of The Better Nutrition Program (BNP), the Nutrition Course Director for UC Irvine's Susan Samueli Integrative Health Institute's Integrative and Functional Medicine Fellowship, and a faculty member at the Integrative and Functional Nutrition Academy (IFNA), where she teaches “An Integrative and Functional Nutrition Approach to Obesity and Weight Management.” She's also the author of the upcoming book, Your Best Shot. As a practitioner for over 25 years, Koff has been recognized as one of CNN's Top 100 Health Makers, featured in InStyle as “Hollywood's Leading Dietitian,” and selected as Westin's Global Nutrition Ambassador. RESOURCES MENTIONED Order my new book: The Perimenopause Revolution https://peri-revolution.com/ Ashley's Book: Your Best Shot GLP-1 Optimization Assessment The Better Nutrition Program Website Ashley on Instagram IN THIS EPISODE Ashley's personal experience with GLP-1s and their success Addressing the judgment around GLP-1 usage in society Overcoming the hurdles regarding accessibility to GLP-1s Looking at trends in current women's health and in children How to reset certain hormones naturally for optimal performance How to cut through the conflicting nutrition advice in the media Why hormones like GLP-1s need to be a part of the midlife conversation About Ashley's new book and The Better Nutrition Program! QUOTES “That means your weight-health hormones are going to be impacted. And let's look at this whole thing systemically– I think there's a lot of ways we can go in this, but one of the things I'm very concerned about is the way that people are being judged.” “I think in that way the biggest answer I would have for you is for us to stop blaming the medication for working the way the medication is supposed to work. And this is where I think the physician and dietician collaboration, comes in and says, actually, these are all the things that we need to experiment with or we need to explore, investigate if this is what your outcome is on the medication.” RELATED EPISODES #621: The Truth About Metabolic Health, Hormones and GLP-1s with Tyna Moore #647: Hormone Optimization Therapy (HOT) Isn't Your Mom's HRT + It's One Of The Best Strategies For Longevity with Dr. Amy Killen #605: Breaking the HRT Confusion: The Truth Behind Hormone Replacement Therapy for Perimenopausal Women with Karen Martel 656: The Dangers Of NOT Prescribing Bioidentical HRT + Migraines, Testosterone and Mitigating Inflammation with Dr. Louise Newson
Pre-Order The Forever Strong PLAYBOOK and receive exclusive bonuses: https://drgabriellelyon.com/playbook/Want ad-free episodes, exclusives and access to community Q&As? Subscribe to Forever Strong Insider: https://foreverstrong.supercast.comAre your immune cells aging faster than you are? In this episode, Dr. Gabrielle Lyon sits down with Dr. Anurag Singh, a leading physician-researcher and Chief Medical Officer at Timeline, to discuss a groundbreaking discovery: the gut-muscle-immune axis. While we often focus on muscle mass for longevity, new research published in Nature Aging reveals that our immune system undergoes a similar decline, with youthful sentinel cells (naive CD8 T-cells) dropping by 75% as we reach age 50. Dr. Singh explains how mitophagy —the targeted recycling of damaged mitochondria—is the key to "rewiring" an aging immune system to fight infection 20% more effectively. In this episode: Alzheimer's of the Muscle: Why sporadic inclusion body myositis (sIBM) is often misdiagnosed as simple aging. The Power of Urolithin A: How this postbiotic compound induces mitophagy to increase mitochondrial abundance by 20% in just 28 days. Immune Imprinting: Why children get 6-8 colds a year while adults only average 2-4. Repurposing Longevity Drugs: Dr. Singh's take on Metformin, Rapamycin, and GLP-1s for life extension. The 1:1 Exercise Rule:Why 150 minutes of moderate activity is the threshold for mitochondrial biogenesis. Thank you to our sponsors: BodyHealth - Use the code LYON 20 to get 20% off your first order https://www.bodyhealthaffiliates.com/73L4QL3/7XDN2/ Timeline - Get 35% off a Mitopure subscription at https://www.timeline.com/drlyon Manukora - Go to https://www.MANUKORA.com/DRLYON to save 31% plus $25 worth of free gifts. Chapters: 0:00 - Can You Tell If Your Immune System Is Healthy? 1:37 - Alzheimer's of the Muscle: Muscle-Immune Dysfunction 5:59 - The Thymus Design Flaw: Why Our Immune "Ammo" Disappears 8:44 - Naive CD8 T-Cells: The Elite Forces of Immunity 12:24 - The Axis of Aging: Mitochondria and Immune Cells in Muscle 16:15 - Mitophagy vs. Autophagy: Targeted Cellular Recycling 19:11 - Study Review: Rewiring the Immune System with Urolithin A 24:13 - Mitochondrial Remodeling: Switching from Glucose to Fatty Acids 27:45 - The Trifecta: Gut-Muscle-Immune Axis Connection 31:13 - Parkinson's and the PINK1/Parkin Mitophagy Pathway 35:04 - Clinical Results: Improving Leg Strength in 4 Months 38:51 - Joint Health: Can We Remodel Cartilage with Mitophagy? 43:34 - Targeted Mitophagy Inducers: Exercise vs. Postbiotics 46:44 - Precision Nutrition: The Ideal Muscle Longevity Supplement 53:33 - Why Alzheimer's is Now Considered an Inflammatory Disease 1:00:13 - The Placebo Effect: You Cannot Deceive the Immune System 1:03:13 - Lymphocyte Counts: The Clinical Marker for Immune Aging 1:08:14 - Rapamycin and Metformin: The Future of Longevity Drugs 1:11:42 - Optimal Dosing: Why 1,000mg of Urolithin A is the Standard 1:15:13 - Sports Medicine: Reducing Muscle Damage Markers (Creatine Kinase) 1:20:03 - The Final Frontier: Brain Aging and Selenium Repair Connect with Dr. Anurag Singh Instagram: @timeline_longevity Website: https://www.timeline.comFind Dr. Gabrielle Lyon at: Instagram:@drgabriellelyon TikTok: @drgabriellelyon
The latest fallout over the U.S. military raid to capture Venezuelan President Nicolás Maduro and what could come next. Also, flu numbers continue to spike, with reported cases hitting 11 million as the virus spreads. Plus, the Kennedy family and loved ones honor Tatiana Schlossberg at a private funeral service in New York. And, a closer look at the impact of the first-ever GLP-1 weight loss pill that's now available in the U.S. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
Today, I'm joined by the insightful Ashley Koff, renowned registered dietitian and fierce advocate for personalized, realistic nutrition that actually works in the real world. In this episode, Ashley Koff opens up about her personal and professional journey—from her early days in big brand marketing (think sugared cereals and infobesity) to her pivotal "aha" moments that led her to champion true weight health, not just weight loss. Episode Timestamps: Welcome and introduction to the Longevity Podcast ... 00:00:00 Personal experiences shaping nutrition philosophy ... 00:05:59 Influence of marketing on nutrition decisions ... 00:09:01 Big revelations: digestion, GLP-1, and health ... 00:16:43 The power of personalization in nutrition ... 00:19:59 The "Mr. Pizza Pop" case and behavioral change ... 00:23:03 Digestion as the foundation before diet quality ... 00:27:05 Dangers of generic "healthy diet" advice ... 00:36:01 GLP-1 medications: promise, risks, and prerequisites ... 00:40:10 Who truly needs GLP-1 versus lifestyle change alone ... 00:43:09 Muscle, bone, and shifting focus to building health ... 00:51:30 Nutrient intake, fiber, and supplement personalization ... 00:55:11 Digestive enzymes and optimizing digestion ... 01:03:10 Food noise, satiety, and psychological freedom ... 01:07:29 Ongoing assessment: tracking weight, fat, muscle ... 01:15:19 Weaning off GLP-1 and the importance of professional support ... 01:18:32 Our Amazing Sponsors: Primeadine by Oxford Healthspan: Primeadine supports autophagy — your cells' natural renewal and cleanup process — using food-derived spermidine, no fasting required. If you want to support resilience from the inside out, head to https://www.oxfordhealthspan.com/BIONAT15 and use code BIONAT15 at checkout (one-time purchases only). Magnesium Breakthrough by BiOptimizers: Better sleep isn't about willpower — it's about absorption. Magnesium Breakthrough uses seven real forms of magnesium that help you rest deeper and recover faster. Get up to 35% off at bioptimizers.com/bionat with code BIONAT. Just Thrive Gut Essentials Bundle: pairs a probiotic proven to arrive 100% alive with digestive bitters that support digestion and curb cravings, so you actually feel the difference fast. Save 20% on your first Gut Essentials Bundle at justthrivehealth.com/NAT20 with code NAT20 — 100% money-back guarantee. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Group
What if the fatigue, stubborn weight changes, brain fog, inflammation, or burnout you're experiencing isn't a failure of willpower, but a signal that your metabolism is under strain? In this solo episode, Dr. Taz unpacks what metabolic health actually means in the age of GLP-1 medications. She explains why weight loss alone is not the same as healing, and how focusing only on the scale can quietly erode muscle, gut function, hormonal balance, cellular energy, and nervous system resilience.You'll learn why so many people lose weight but still feel exhausted, inflamed, anxious, or disconnected from their bodies. Dr. Taz breaks down the six core metabolic engines that regulate energy, fat storage, blood sugar, hormones, stress response, and longevity, and why ignoring even one of them can stall long-term health.This episode reframes metabolism as a full body system. One that includes the gut microbiome, hormone signaling, mitochondrial function, liver detoxification, muscle health, and the nervous system. When these systems fall out of sync, weight becomes a symptom, not the root issue.Dr. Taz shares: • Why GLP-1 medications support weight loss but do not repair metabolic dysfunction • How up to 25% of weight lost on GLP-1s can come from muscle, impacting long-term health and longevity • Why the gut is the foundation of metabolic health and how digestion, bile flow, and microbiome balance shape hormones and inflammation • How hormone shifts, especially in midlife, can rapidly disrupt blood sugar, cholesterol, energy, and weight • The role of cellular and mitochondrial health in fatigue, brain fog, and metabolic slowdown • Why liver function is central to detoxification, fat metabolism, and insulin regulation • How stress and nervous system dysregulation can drive cravings, poor sleep, and metabolic instability • How to identify which metabolic engine needs attention first so your plan stays targeted and sustainableWhether you're currently on a GLP-1, considering one, struggling after coming off, or simply want to build metabolic health that lasts for decades, this episode offers a grounded, integrative roadmap. You don't need to chase trends or stack solutions. You need to understand the system you're living in.You may not control every variable that shaped your metabolism, but you can change how it functions moving forward.Stay Connected:Connect further to Hol+ at https://holplus.co/- Don't forget to like, subscribe, and hit the notification bell to stay updated on future episodes of hol+.Follow Dr. Taz on Instagram: https://www.instagram.com/drtazmd/https://www.instagram.com/liveholplus/Subscribe to the audio podcast: https://holplus.transistor.fm/subscribeSubscribe to the video podcast: https://www.youtube.com/@DrTazMD/podcastsGet your copy of The Hormone Shift: Balance Your Body and Thrive Through Midlife and MenopauseHost & Production TeamHost: Dr. Taz; Produced by ClipGrowth.com (Producer: Pat Gostek)
Mark Cuban approaches healthcare the same way he approaches every industry he enters: by assuming something essential is missing and then asking who benefits from keeping it that way. In American medicine, he believes that missing ingredient is transparency. Not better messaging, not smarter incentives, but simple visibility into how prices are set, who gets paid and who gets taken advantage of. Cuban is a lifelong healthcare outsider. He is a billionaire entrepreneur, NBA championship team owner and longtime Shark Tank investor. That's what makes him the perfect guest for Season 11 of Fixing Healthcare with cohosts Dr. Robert Pearl and Jeremy Corr. This season's guests have massive online audiences, but their value isn't just reach. It's their ability to listen closely to what millions of patients are experiencing, then translate those insights back into the broader medical conversation. Few guests embody that better than Cuban. He has quickly become one of the system's most incisive critics by paying attention to what patients, employers and clinicians repeatedly say is broken. That mindset led to the creation of Cost Plus Drugs, a pharmacy built on an idea that sounds radical only because healthcare has drifted so far from it. Show patients the actual cost of a medication, add a flat 15% markup and eliminate the opaque middlemen who thrive in the dark. In this conversation, Cuban explains how a cold email from a physician opened his eyes to how hidden pharmaceutical pricing had become and why opacity itself became the opportunity. HIGHLIGHTS FROM THE INTERVIEW Why drug prices are detached from reality. Cuban breaks down how widely used medications, including GLP-1 weight-loss drugs, can cost hundreds or thousands of dollars per month despite far lower manufacturing costs. The driver, he argues, is not innovation or scarcity, but a system dominated by pharmacy benefit managers whose rebate structures reward insurers and intermediaries while excluding patients. How patients bear the greatest financial harm. With concrete examples, Cuban explains how people in deductible phases, especially those on ACA plans, often pay full retail prices while rebates flow elsewhere. Costs are spread across millions of plan holders, but the financial pain lands on the people who actually need care. Why healthcare's complexity is intentional. From fax machines to prior authorization delays, Cuban argues that administrative friction is not accidental. It protects incumbents, drains clinician time and forces providers into the role of “subprime lenders,” all while patients struggle to navigate a system designed to obscure accountability. What he tells CEOs behind closed doors. Cuban outlines the first questions he asks corporate leaders about their pharmacy benefits, why most are not receiving the rebates they believe they are and how audits are often structured to reveal as little as possible. Transparency, he says, is the first step toward leverage. A blueprint beyond pharmaceuticals. The discussion extends into hospitals, insurance design and employer-based coverage, including Cuban's work on cost-plus wellness contracts that publish negotiated rates so others can replicate them. His goal is not dominance. It is forcing the system to respond by making its incentives visible. Throughout the episode, Cuban's message is blunt and consistent. Healthcare does not need more jargon, better marketing or marginal tweaks. It needs sunlight. Once pricing, incentives and risk are exposed, many of the system's most entrenched practices become much harder to justify. * * * Fixing Healthcare is a co-production of Dr. Robert Pearl and Jeremy Corr. Subscribe to the show via Apple, Spotify, Stitcher or wherever you find podcasts. Join the conversation or suggest a guest by following the show on Twitter and LinkedIn. The post FHC #201: Mark Cuban’s blunt diagnosis of what’s broken in healthcare appeared first on Fixing Healthcare.
Midlife fitness for women 45+ is not about trying harder—it's about training smarter for perimenopause and menopause physiology. In this powerhouse episode of Asking for a Friend, host Michele Folan sits down with Dr. Stacy Sims—exercise physiologist, TEDx speaker behind “Women Are Not Small Men,” and author of ROAR and Next Level—to break down exactly why your old workouts and “eat less, do more cardio” strategies stop working in midlife… and what to do instead.We get practical (and refreshingly no-BS) about the real midlife playbook:Why estrogen shifts change metabolism, muscle power, recovery, and body compositionWhy heavy lifting matters (and why it won't make you “bulky”)The difference between HIIT vs. Sprint Interval Training (SIT)—and why many “HIIT classes” aren't actually HIITWhere Zone 2 fits (and why it's great for mental health, but not your best lever for optimization)The truth about fasted workouts and intermittent fasting for women—and how it can backfire on appetite, cravings, energy, and sleepHow to think about protein needs in midlife (including the “1 gram per pound” conversation and how to distribute it)Why creatine is having a moment (brain, muscle, mood, performance, and aging)—and what dosing typically looks likeRecovery upgrades in perimenopause/menopause: sleep, mobility, heat/sauna (and why cold plunge isn't a one-size-fits-all tool for women)Why testing and metrics like DEXA (bone density + body comp) and VO2 max can be useful for longevity-focused womenIf you've been standing in your kitchen wondering where your “30-year-old metabolism” went—and why you can't out-discipline midlife hormones—this episode will give you clarity, strategy, and a realistic path forward.You can find her newsletter and blog at: https://www.drstacysims.com/ You can receive 15% off her online courses at https://www.drstacysims.com/product_guide using the code DRSTACYSIMS15OFFhttps://www.instagram.com/drstacysimshttps://www.youtube.com/channel/UCPD55VPa1ZWx1a_nzWC2VJA_________________________________________1:1 health and nutrition coaching or Faster Way - Reach me anytime at mailto:mfolanfasterway@gmail.com If you're doing “all the right things” and still feel stuck, it may be time to look deeper. I've partnered with EllieMD, a trusted telehealth platform offering modern solutions for women in midlife—including micro-dosed GLP-1 peptide therapy—to support metabolic health and longevity. https://elliemd.com/michelefolan - Create a free account to view all products. ✨ Sign up for my weekly newsletter: https://michelefolanfasterway.myflodesk.com/i6i44jw4fq
Today on AirTalk: California's snowpack (0:15) New UCLA study on pollutants in burn area homes (9:44) Is it cringe to dance now? (33:39) GLP-1 check-in (50:46) Is being late an ADHD symptom? (1:26:11) Visit www.preppi.com/LAist to receive a FREE Preppi Emergency Kit (with any purchase over $100) and be prepared for the next wildfire, earthquake or emergency
This episode opens the year with one of the most consequential—and complicated—weeks in GLP-1 obesity medicine. We break down three stories that, taken together, reveal why patients are increasingly reading past headlines and demanding accountability from the industry. First, we examine early-phase trial data from Arrowhead Pharmaceuticals, after headlines claimed its experimental INHBE-targeting therapy “nearly doubled” the weight loss of Zepbound. We walk through what the data actually showed, why the comparison was misleading, how trial design and dosing matter, and why Phase 1 results should never be treated as superiority claims. Next, we turn to a major access milestone: the official launch of oral Wegovy, the first FDA-approved GLP-1 pill for obesity from Novo Nordisk. We discuss how this pill differs from compounded oral semaglutide, why its pricing strategy is so disruptive, and what this launch means for people who have avoided injectable medications. We also explore how direct-to-consumer access, telehealth partnerships, and retail pharmacy distribution signal a broader shift in how obesity care is being delivered. Finally, we address the most ironic—and uncomfortable—story of the week: manufacturing quality concerns involving branded Wegovy pens, reported to include biological particulate matter, at the same time Novo Nordisk continues a years-long public and legal campaign against compounded GLP-1 medications on safety grounds. We discuss FDA inspection history, the acquisition of Catalent, and why credibility depends on consistency—especially when millions of patients are paying close attention. This episode isn't anti-pharma or pharma-friendly. It's patient-first. And it asks a simple question: Who do we trust when science, marketing, access, and manufacturing all collide at once? Episode Timestamps 00:00 — Why this first episode of 2026 matters 02:10 — Hair found in Wegovy pens and why patients notice hypocrisy 06:15 — Arrowhead trial headlines vs. what the data actually shows 11:40 — Why tirzepatide dosing and trial design matter 17:30 — What INHBE targeting may actually be good for (and what it's not) 21:45 — Sponsor: SHED and access pathways for obesity care 25:10 — Oral Wegovy officially launches: what's different this time 30:20 — How the Wegovy pill works and why bioavailability matters 35:40 — Pricing, telehealth, Costco, and direct-to-consumer access 41:50 — Why pills lower barriers for millions of patients 46:10 — Manufacturing quality, Catalent, and FDA citations 52:30 — Why safety arguments against compounding are being scrutinized 58:40 — Zooming out: access, accountability, and patient trust 1:02:00 — Final thoughts and what to watch next Topics Covered GLP-1 trial hype vs. real-world context Phase 1 data limitations and headline inflation Tirzepatide dosing and misleading comparisons Oral Wegovy vs. compounded oral semaglutide GLP-1 pill pricing and insurance implications Direct-to-consumer pharma and telehealth disruption Manufacturing quality and FDA oversight Compounding pharmacies and healthcare system resilience Patient trust, transparency, and credibility in obesity medicine Useful Links & Resources On The Pen Links & Advocacy: https://otplinks.com Sponsor – SHED (use code OTP25): https://tryshed.com FDA Drug Safety & Recalls: https://www.fda.gov/drugs Follow On The Pen: YouTube: https://youtube.com/@onthepen Substack: https://onthepen.substack.com Support the Show If this episode helped you better understand what's really happening in obesity medicine: Leave a 5-star rating and review Hit Subscribe so you don't miss future episodes Join us live Mondays, Wednesdays, and Fridays at 12pm Eastern on YouTube Patients deserve clarity. That's what we're here for. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
A 60-year-old male with documented ASCVD, obesity with BMI of 34, and type 2 diabetes presents for care. The patient reports he's currently feeling well without episodes of hypoglycemia. Current laboratory assessment includes the following. A1C is 8.6 % and his estimated GFR is at 62. Current medications include metformin at optimized dose and a sulfonyl urea.Which of the following represents the nurse practitioner's next best action?A. continue on current therapy and arrange for a three month follow upB. discontinue the metformin and add a DPP4 inhibitorC. add a GLP-1 inhibitor and discontinue the sulfonyl ureaD. add basal insulin and titrate to fasting glycemic goals---YouTube: https://www.youtube.com/watch?v=8ybH1qcskq8&list=PLf0PFEPBXfq592b5zCthlxSNIEM-H-EtD&index=124Visit fhea.com to learn more!
Midlife weight gain, burnout, and metabolic changes often get mislabeled as willpower issues. This episode challenges the oversimplified weight loss narrative and unpacks why many women feel blindsided by changes even when their habits stay solid.We dive deeper into this in the Broads episode with Dr. Tyna Moore. We also chat about why GLP-1 was never meant to be a vanity weight loss tool, why microdosing doesn't mean what most people think it means, and the real risks of frailty and why strength equals long-term freedom.Dr. Tyna Moore is a Licensed Naturopathic Physician and Chiropractor with over 30 years in the medical field, specializing in holistic regenerative and metabolic medicine. She earned her degrees from the National College of Natural Medicine and the University of Western States Chiropractic College. Dr. Tyna is also the host of The Dr. Tyna Show and an international speaker.What's Discussed:(08:48) How being “early” to the GLP-1 conversation led to backlash and burnout(10:49) How GLP-1 became misused and distorted by telemedicine and influencers(15:18) Why midlife weight gain isn't about willpower but a neurological shift(16:09) The idea of functional deficiency and why modern stress breaks signaling(19:15) How GLP-1 can increase motivation to move through brain plasticity(22:20) How GLP-1 can magnify existing hormonal deficiencies in women(24:11) Why movement is essential for gut health and metabolic signaling(28:01) Why microdosing is not a true weight loss strategy(35:44) Why strength training is non-negotiable for women in midlife(39:02) The real risks of frailty, hip fractures, and loss of independenceCheck out more from Broads:Website: www.broads.appInstagram: @broads.podcast @broads.appCheck out more from Tara LaFerrara:Website: www.taralaferrara.comInstagram: @taralaferraraYoutube: @TaraLaferraraTiktok: @taralaferraraCheck out more from Dr. Tyna, ND, DC:Website: www.drtyna.comInstagram: @drtynaYoutube: @drtyna
In this episode, I sit down with Dr. Jeff Skarela—a sports chiropractor, competitive triathlete, and my personal go-to guy for performance recovery and injury prevention. Whether you're a weekend warrior, high-level athlete, or the parent of a competitive teen, this one's packed with practical insight you can actually use.We talk about VO₂ max, lactate threshold, muscle scraping, BFR, peptides, exosomes, GLP-1s, cold plunges, saunas, and more. You'll hear how Jeff treats his patients like athletes—designing concierge, one-on-one recovery sessions that keep them training, moving, and competing. We also dive into how the science of recovery is changing: why ice may be outdated, why range of motion is king, and how the "Enhanced Olympics" are reshaping our views on optimization. This is a crash course in high-performance human care—without the fluff.Quotes"My ideal patient? Someone who's already healthy—and wants to stay that way. That's the real goal." — Dr. Jeff Skarela"VO₂ max is a proxy. You can't cheat it. You either put in the work—or you didn't." — Dr. Jeff SkarelaKey TakeawaysIntro: Who is Dr. Jeff Skarela? (00:00)Sports chiropractic vs. traditional chiro or PT (02:24)VO₂ max, lactate threshold, and what actually matters (09:38)How to train your VO₂ with max-effort intervals (13:04)Why muscle scraping and manual therapy matter (16:20)What is shockwave therapy and when to use it? (19:09)The truth about GLP-1 drugs and muscle loss (31:44)Building lean muscle after 40: resistance + protein (28:45)Why Dexa scans matter more than a scale (29:51)Ice vs. heat: why rest and compression may beat icing (57:57)Are statins causing your muscle issues? (34:10)The promise and limits of peptides and growth hormone (37:02)Blood flow restriction (BFR) training explained (45:00)Compression boots, cold plunges, and recovery hacks (23:01 & 49:17)What are exosomes and why they may matter next (54:45)The "Enhanced Olympics" and the future of performance (38:29)Additional ResourcesIf you're serious about staying active, feeling strong, and recovering faster—this episode is your roadmap. Whether you're 27 or 57, you can't afford to guess anymore when it comes to health and performance.
What if this year isn't about resolutions—but about habits that actually last?In this episode of The Common Sense MD, Dr. Tom Rogers shares a practical approach to creating your healthiest new year by focusing on human behavior—not willpower. He explains why weight loss tops most wish lists, why GLP-1 medications are one of the most significant medical advances of our time, and how real change comes from developing better daily habits.A must listen for making 2026 your healthiest year!What did you think of this episode of the podcast? Let us know by leaving a review!Connect with Performance Medicine!Check out our new online vitamin store:https://performancemedicine.net/shop/Sign up for our weekly newsletter: https://performancemedicine.net/doctors-note-sign-up/Facebook: @PMedicineInstagram: @PerformancemedicineTNYouTube: Performance Medicine
Nutritious Life PodcastIn this timely episode of the Living a Nutritious Life Podcast, we are thrilled to welcome Ashley Koff, RD, a nationally recognized dietitian, author, and nutrition expert.About Our Guest:Ashley Koff, RD, is the founder of The Better Nutrition Program (BNP) and the author of the newly released book, Your Best Shot. An acclaimed weight-health expert and practitioner for more than 25 years, Koff is leading a transformative movement in personalized nutrition, turning “better, not perfect” choices into practical, sustainable strategies that deliver real outcomes.What You'll Learn in This Episode:- The critical role of "weight health hormones" (including GLP-1, PYY, CCK, and GIP) in metabolism, appetite, and overall well-being.- Why weight loss and health have long been separated—and how to finally bridge them for lifelong results.- How optimizing your own hormones is essential, whether or not you use GLP-1 agonist medications.- Why personalized assessment and nutrition matter more than any fad diet, supplement, or one-size-fits-all approach.Episode Highlights:- The science behind the GLP-1 hormone, how GLP-1 agonists work, and why they're reshaping weight health (and medicine!).- Ashley's signature “pizza analogy” to make customizing your nutrition plan simple and sustainable.- The most overlooked nutrients and habits that support your body's own hormonal balance and weight regulation.- A candid discussion about medication, teens, and why every individual needs a personalized approach—plus how Ashley's own story shaped this movement.About Living a Nutritious Life Podcast: Welcome to the Living a Nutritious Life podcast with Keri Glassman, MS, RDN, CDN, where we break down the latest nutrition science into smart, actionable tips to help you live your most nutritious life.On the Living a Nutritious Life podcast, Keri and her world-renowned guests cut through the noise, sharing unparalleled, forward-thinking tips, tricks, and the latest in health, wellness, and nutrition science.Based on Keri's whole-person approach to healthy living, each impactful episode extends far beyond the simplistic “get more sleep” and “eat your greens” advice. She connects the dots like no one else – like how morning yoga can make it easier to choose a healthy lunch, leading to better sleep at night.Listen as Keri and her expert guests explore the physiological and behavioral connections that explain, for example, why the common wisdom around dieting and exercising alone doesn't work, so you can finally make the meaningful changes you've been looking for.Thank you for listening in to this episode of Living a Nutritious Life. We hope you enjoyed the conversation as much as we did! If you found value in this episode, please RATE, REVIEW and SHARE.Ready to Dive Deeper? Are you ready to dive into the world of nutrition and wellness even deeper and become a certified nutrition coach? Join our amazing global community of like-minded students and alumni. Get in on the action—enroll in our Become a Nutrition Coach program at nutritiouslife.com/bnc. Keri has a lot to teach, and we're here to help you get started on your journey!Connect with Ashley on social:IG: www.instagram.com/ashleykoffapprovedWebsite: https://thebetternutritionprogram.com/Your Best Shot: https://thebetternutritionprogram.com/your-best-shot/#OrderConnect with Keri on social: Instagram: https://www.instagram.com/nutritiouslifeofficial/ Instagram: https://www.instagram.com/keriglassman/ TikTok: https://www.tiktok.com/@keriglassman Facebook: https://www.facebook.com/KeriGlassmanNutritiousLife Twitter: https://twitter.com/NutritiousLife_ LinkedIn: https://www.linkedin.com/company/nutritiouslife Pinterest: https://www.pinterest.com/nutritious_life/ Website: https://nutritiouslife.com/ Become a Nutrition Coach: https://nutritiouslife.com/bnc/Copyright © 2023-2025 Nutritious Life.#LivingaNutritiousLife #NutritiousLife Hosted on Acast. See acast.com/privacy for more information.
Happy New Year! This time of the year, most declare their resolutions - a huge majority including diet and weight loss, but what is the best way to do it?In this episode, our Chief Science Officer, Dr. Krista Kostroman, N.D., is joined by Ashley Koff, R.D., the founder of The Better Nutrition Program (BNP), the nutrition course director for UC Irvine's Susan Samueli Integrative Health Institute's Integrative and Functional Medicine Fellowship, and a faculty member at the Integrative and Functional Nutrition Academy (IFNA), where she teaches “An Integrative and Functional Nutrition Approach to Obesity and Weight Management.”She is also the author of the recently released book Your Best Shot (HarperOne, Jan. 6, 2026). With over 25 years of practice, Ashley leads a transformative movement in personalized nutrition — turning “better, not perfect” choices into practical, sustainable strategies that create meaningful health outcomes. Through patient stories and personal experience, she demonstrates that optimal health isn't just possible — it's essential to living a full life.Her work has been recognized widely: she was named one of CNN's Top 100 Health Makers, featured in InStyle as “Hollywood's Leading Dietitian,” and selected as Westin's Global Nutrition Ambassador.Join us today as we uncover the science and truth about weight health and nutrition! This includes the following highlights:What our genetics says about our weight, diet, and nutritionWhat GLP-1s arePersonalized Nutrition and how to create sustainable strategies for optimal health and weight lossHow supplements affect our diet and nutritionAshley Koff's book, “Your Best Shot”If you wish to learn more from Dr. Emily Splichal and Naboso, you may do so through the following channels:Website: https://thebetternutritionprogram.com/about/Instagram: @thebetternutritionprogramCheck out Ashley's book at: Your Best Shot: The Personalized System for Optimal Weight Heath - GLP-1 Shot or Not (Harper One, January 6, 2026). Out now wherever books are soldThe real revolution of the GLP-1 shots is the insight that the body regulates appetite and more with the hormones GLP-1, GIP, PYY, and CCK—and with Your Best Shot in hand, you can learn to optimize their function and your weight health for life______________________________________________________Keep yourself up to date on The DNA Talks Podcast! Follow our socials below:The DNA Talks Podcast Instagram: @dnatalkspodcastThe DNA Company Instagram: @thednacoThe DNA Company's Official Tiktok Account: @thednaco3______________________________________________________Medical Disclaimer: The information provided in this communication is for general informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read here. If you think you may have a medical emergency, call your doctor or 911 immediately.
In today's episode, I'm sitting down with one of my clients and friends, Katie, to have an honest, real conversation about food, midlife, menopause, mindset, and what it actually takes to create lasting change.-------------------If you're listening in real time, make sure to sign up for my Free Webinar "Your Year of Change" HERE.-------------------Katie had been listening to this podcast for a long time before we worked together. She understood the concepts intellectually. She wanted things to change. But like so many women, she found herself stuck in the cycle of trying hard, tightening down, losing control, and then blaming herself.In this episode, we talk about what finally shifted.Katie shares what it felt like to go from feeling helpless around food to feeling calm, grounded, and in control—without dieting, restriction, or perfection. We talk openly about menopause, inflammation, exercise no longer “working” the way it used to, and the cultural story that midlife weight gain is inevitable.We also dive into something bigger than weight loss.Katie explains how learning to manage her thoughts—not just her food—changed how she shows up with her kids, her husband, her work, and even her aging parents. One of my favorite moments in this conversation is when she shares how the mindset tools we use helped her respond differently to everyday stress instead of numbing out with food.We also have an honest conversation about using GLP-1 medications as a tool. Katie shares why she chose to use them, the stigma she felt, and why mindset work is still essential if you want the results to last—whether you're on medication or not.If you've ever:Felt like you should be able to do this by nowWondered why what worked in your 30s and 40s no longer worksFelt stuck consuming information but not creating real changeOr worried that focusing on food might negatively impact your kids…this episode is for you.Katie's story is a reminder that you're not broken—and that real freedom around food is possible at any age when you stop relying on willpower and start changing how you think.You are invited to my FREE Webinar Your Year of Change....click HERE to sign up.We start January 21st! Enrollment is NOW OPEN for my Modern Change Group Coaching Program.....find all the details and enroll HERE. *Space is limited as I keep my group programs small.
Join My Private Group: https://theaxioncollective.manus.space/Email List: https://huntershealthhacks.beehiiv.com/Get My Book On Amazon: https://a.co/d/avbaV48DownloadThe Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/1 On 1 Coaching Application: https://hunterwilliamscoaching.carrd.co/Book A Call With Me: https://hunterwilliamscall.carrd.co/Supplement Sources: https://hunterwilliamssupplements.carrd.co/Amazon Storefront: https://www.amazon.com/shop/hunterwilliams/list/WE16G2223BXA?ref_=cm_sw_r_cp_ud_aipsflist_R7QWQC0P1RACB2ETY3DYSocials:Instagram: https://www.instagram.com/hunterwilliamscoaching/Video Topic Request: https://hunterwilliamsvideotopic.carrd.co/In this episode, I dive deep into a topic that's been coming up more and more over the last 12–18 months: anhedonia and motivational blunting in people using GLP-1 agonist peptides. While GLP-1s like semaglutide, tirzepatide, and retatrutide have been absolute game-changers for weight loss, metabolic health, and even addictive behaviors, there's a smaller—but very real—subset of people who experience something unexpected: a reduced ability to feel pleasure.Personally, I've never experienced this side effect. In fact, GLP-1s have done the opposite for me by giving me more mental clarity and freedom from compulsive behaviors. But enough people have reported feeling emotionally flat, unmotivated, or disconnected from things they used to enjoy that it deserves a serious, evidence-based conversation.In this episode, I break down what anhedonia actually is, how it differs from depression, and why it can happen with GLP-1s from a neurochemical standpoint—specifically dopamine signaling and reward circuitry in the brain. We'll look at the clinical data, real-world reports, differences between GLP-1 compounds, and why dose, speed of titration, weight loss, hormones, and lifestyle factors all matter.Most importantly, I share practical strategies for mitigating these effects so you can still harness the benefits of GLP-1s without sacrificing joy, motivation, or quality of life.
Advancing longevity research is about honoring the value of life—and translating that respect into evidence-based prevention. If healthcare is judged by life expectancy + quality of life, longevity medicine may be one of the most meaningful metrics we can pursue: extending health span through early detection, validated biomarkers, and interventions that scale.This unforgettable Expert Panel from the 4th annual Medical Innovation Olympics (#MIO2025) convened all-star global leaders in Longevity and Preventive Medicine who separated hype from reality and outlined what it will take to bring longevity into mainstream care - rigorously, ethically, and accessibly.Topics include: breakthroughs (including epigenetic approaches pointing toward functional restoration of eyesight), biomarkers/endpoints as the “keystone” for faster trials, the TAME (Targeting Aging with Metformin) concept, and the role of standards, education, trust, and shared responsibility—keeping dignity central.Panelists:Dr. David Barzilai (Harvard Medical School; Geneva College of Longevity Science, GCLS) • Dr. Dominik Thor (President, GCLS) • Dr. Mishkat Shehata (Emirates Lifestyle & Longevity Medicine Society) • Keith Comito (Lifespan Research Institute) • Dr. Uma Senthilkumar (Three Five Revive)
Predictions are everywhere, but the real question is what is changing underneath them. In 2026, the pressure is stacking, the signals are getting noisier, and leaders will be judged on clarity and trust.Anne Green and Steve Halsey share their 2026 predictions and use them as a way to talk through the forces reshaping how brands operate and communicate. They cover the volatility “pressure stack,” the trust crisis of synthetic reality, and why AI is moving from experimentation to standard operating practice, with discipline becoming the differentiator. They also dig into cross sector signals leaders cannot ignore, including the ripple effects of GLP-1s and the growing role of external validation in B2B. The episode lands on two clear leadership shifts: invest in the human side of AI transformation, and treat corporate narrative like an operating system, not a campaign.In this episode:12 predictions for 2026 across AI, trust, narrative, healthcare stress, and volatilityWhy synthetic content and compressed news cycles raise the bar for proof and credibilityWhat AI standardization really means, plus the people gap leaders keep underfundingThe case for narrative as an operating system that keeps your story coherent over time
VR headsets, a woman allegedly running over her boyfriend on a sidewalk after an argument at a Taco Bell, the first GLP-1 weight-loss pill now available with a promise of widespread supply, and “Drinking Around the World” at Walt Disney World — plus more news. Plus, joining us in the studio today is Chamber of Commerce President and CEO Glen Brewer, stopping by to talk about upcoming events like Business After Hours, the Economic Outlook Conference, and the Cellular Cells ribbon-cutting event this Friday.
View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter Abbie Smith-Ryan is a leading researcher in exercise physiology whose work focuses on how training and nutrition influence body composition, metabolism, cardiovascular health, and women's health across the lifespan, with particular attention on perimenopause and post-menopause. In this episode, Abbie explains how early exercise and play help build the foundation for bone health, muscle development, and cardiorespiratory fitness in girls, as well as how puberty and menstruation shape athletic performance, motivation, and recovery. She also explores how women can tailor training and nutrition across the menstrual cycle through smart fueling, hydration, and inflammation management; examines the evidence behind supplements such as creatine, omega-3s, and magnesium; and unpacks the metabolic and body composition changes that accompany the transition into perimenopause and menopause. Finally, she covers practical exercise programming for busy women, training and nutrition considerations during pregnancy and postpartum, and the evolving role of hormone therapy alongside lifestyle-based, evidence-driven approaches that help women better advocate for their health. We discuss: Abbie's background in distance running and her interest in studying women's health around exercise [3:00]; The role of early-life exercise in building lifelong bone, muscle, and cardiovascular health in girls [4:00]; Training principles for premenstrual girls, the risks of early specialization and delayed puberty from intense training, and how youth sport participation can shape bone and spinal health [7:15]; Nutrition as fuel in young female athletes: supporting training, growth, and performance [11:00]; Training and recovery across the menstrual cycle: recovery, nutrition, supplements, and practical strategies for performance support [16:00]; The benefits of creatine supplementation and importance of protein intake across the menstrual cycle [27:15]; How women should approach training intensity and volume across the menstrual cycle [33:00]; How to identify and monitor the perimenopausal transition and why this phase represents a critical window for exercise and nutrition interventions [37:15]; Case study: time-efficient exercise program for a busy, perimenopausal woman [42:00]; Why improving body composition is a better goal than weight loss, and how to set realistic fat-loss targets in midlife women [53:30]; How to preserve muscle and bone while using GLP-1 medications: resistance training, protein intake, and more [58:15]; Designing a three-hour-per-week training plan for sustainable body recomposition [1:03:30]; Abbie's insights from her 20+ years of self-tracking: nutrient timing, injury prevention, excessive training, bone health, and more [1:07:15]; How pregnancy and the postpartum period affect body composition, and how consistent exercise and intentional nutrition can prevent a permanent shift in body fat or muscle mass [1:13:30]; Changes in muscle quality and metabolic flexibility during perimenopause and menopause, and how exercise may counteract hormonally driven sarcopenia [1:21:45]; The biggest open questions about women's health: combining menopause hormone therapy with exercise, GLP-1 drugs, minimizing injury risk, and more [1:32:00]; How the training response differs between men and women, and the importance of type IIa muscle fibers [1:39:15]; Training advice for the hypothetical 70-year-old woman who has never exercised deliberately [1:47:00]; Misinformation about exercise and nutrition for women, injury risk, supplement hype, and the need for more nuanced messaging around hormones, recovery, and midlife training [1:53:30]; Benefits of hormone therapy in midlife women and its interaction with exercise and lifestyle interventions [2:00:15]; Peter's overall take on how women should approach exercise volume and intensity at various life phases and time constraints [2:03:00]; and More. Connect With Peter on Twitter, Instagram, Facebook and YouTube
When it comes to weight loss, there are many misconceptions about what works. So if you want to lose weight this year, here's what the science says about the potential health benefits, GLP-1 drugs, exercise and more.Sign up for Life Kit's Guide to Building Strength here: npr.org/strongerFollow us on Instagram: @nprlifekitSign up for our newsletter here.Have an episode idea or feedback you want to share? Email us at lifekit@npr.orgSupport the show and listen to it sponsor-free by signing up for Life Kit+ at plus.npr.org/lifekitLearn more about sponsor message choices: podcastchoices.com/adchoicesNPR Privacy Policy
Dopamine expert DR ANNA LEMBKE reveals how addiction is hijacking your brain, why dopamine addiction is rising fast, the danger of social media, porn, AI, GLP-1 drugs, and how to regain control FAST! Dr Anna Lembke is Professor of Psychiatry and Medical Director of Addiction Medicine at Stanford University School of Medicine. She has spent over 25 years treating patients with substance and behavioral addictions and is the bestselling author of “Dopamine Nation”. She explains: ◼️Why endless pleasure quietly trains your brain to feel worse, not better ◼️How digital habits replace real connection with instant validation ◼️Why dopamine spikes always come with a hidden crash ◼️How easy comfort erodes discipline, motivation, and intimacy ◼️The practical reset that restores balance and control 00:00 Intro 03:05 Dopamine and Overabundance 04:22 How to Shake Bad Habits 06:16 Why Are Harmful Substances Addictive? 07:15 The Dangers of AI Simulating Human Connection 12:54 Sex Addiction Case Study 19:29 Elon Musk's Age of Abundance 22:23 We're Entertaining Ourselves to Death 23:35 How Our Brain Processes Pleasure and Pain 28:51 Why Do We Fall Off Our Good Habits? 30:40 When Are We Most Susceptible to Self-Destructive Behaviours 31:53 Who Is More Vulnerable to Addiction? 32:59 Link Between Addiction and People With ADHD 34:26 Link Between Childhood Trauma and Addiction 35:57 Parents Soothing Child's Emotions With Technology 37:24 AI Replacing Parenting 40:05 Are You Hopeful People Will See the Downsides of AI? 43:23 Social Media Trials 45:12 Ads 46:07 The Science Behind How to Get Rid of Bad Habits 53:31 Is Addictive Personality a Real Thing? 54:20 4-Week Resolutions 56:24 Psychological Strategies for Adopting Good Habits 59:00 How to Trick Your Brain to Enjoy Doing Hard Things 01:02:06 How to Avoid Relapse 01:04:23 Is It Possible to Become Addicted to Good Things Too? 01:05:11 Daily Routines to Kick the Habit 01:07:10 The "Count Back" Trick to Start New Habits 01:10:24 Ads 01:12:24 Brains of Addicted vs. Non-Addicted People 01:17:42 Dopamine Research That Stood Out for You 01:19:22 Impact of Dopamine Addiction on Personal Relationships 01:22:52 Dopamine Agonist Drugs 01:26:27 Dopamine Release Associated With Learning and Impediments 01:32:13 Radical Honesty 01:37:06 What Is Agency and Why Does It Matter 01:38:58 The Biggest Problem With New Year's Resolutions Follow Dr Anna Website - https://bit.ly/4pS0ckD Stanford Medicine - https://stan.md/4oXiyzq You can purchase Dr Anna's book, ‘The Official Dopamine Nation Workbook: A Practical Guide to Overcoming Addiction in the Age of Indulgence', here: https://amzn.to/4oZKEdl The Diary Of A CEO: ◼️Join DOAC circle here - https://doaccircle.com/ ◼️Buy The Diary Of A CEO book here - https://smarturl.it/DOACbook ◼️The 1% Diary is back - limited time only: https://bit.ly/3YFbJbt ◼️The Diary Of A CEO Conversation Cards (Second Edition): https://g2ul0.app.link/f31dsUttKKb ◼️Get email updates - https://bit.ly/diary-of-a-ceo-yt ◼️Follow Steven - https://g2ul0.app.link/gnGqL4IsKKb Sponsors: Shopify - https://shopify.com/bartlett Intuit - If you want help getting out of the weeds of admin, https://intuitquickbooks.com Bon Charge - http://boncharge.com/diary?rfsn=8189247.228c0cb with code DIARY for 25-30% off
Scott and Jenny review the newly released 2026 ADA Standards of Care, praising key updates like hospital safety protocols while critiquing the "slow drift" of official guidance compared to real-world management. Topics Discussed: The "Slow Drift" of Guidance: Scott analyzes how standards often lag behind effective real-world management, comparing current advice to guidelines from 2018 and 2022. GLP-1s for Type 1: The new guidance explicitly lists GLP-1 receptor agonists as a treatment option for obesity in people with Type 1 diabetes. Technology Access: The requirement for C-Peptide levels or antibody presence has been removed for initiating insulin pumps or AID systems. Hospital Safety: A crucial new standard mandates that basal insulin should never be held for patients with Type 1 diabetes in the hospital. Workplace Advocacy: New language supports reasonable accommodations for adults using diabetes technology (pumps/CGMs) in the workplace. Cannabis Warning: The standards include a new specific warning against cannabis use for those at risk of DKA due to concerns about "cannabis hyperemesis syndrome".
Dr. Stephanie goes "holiday-solo" for the third and final time this week to discuss the growing claim that obesity is mainly genetic, with diet and exercise only accounting for 15% of results. She explains why this messaging is scientifically questionable and potentially harmful, especially for women in perimenopause and menopause who feel powerless. In this candid solo episode, Dr. Stephanie addresses the recent trend of medical professionals suggesting that GLP-1 medications like Ozempic are more effective than lifestyle interventions, and why this approach undermines women's agency. She acknowledges genetic predispositions but argues that resistance training and protein-forward nutrition should remain our primary tools for metabolic health.Episode overview:(0:00) Intro/Teaser(2:00) The Instagram Post(4:00) The Role of Neurochemicals in Obesity(5:00) Glucose Metabolism and Muscle Quality(6:00) Hormonal Changes in Midlife(7:00) Critique of Genetic Determinism in Obesity(12:00) The Importance of Diet and Exercise(19:00) Teaching Healthy Habits to Children(21:00) Final Thoughts and Action StepsResources mentioned in this episode can be found at https://drstephanieestima.com/podcasts/ep450/We couldn't do it without our sponsors:PIQUE - Designed to deeply hydrate, enhance skin elasticity & firmness and support sustained energy—exactly what we need during this stage of life. Start your daily ritual today with 20% off for life—plus a free gift to elevate your routine. Head to https://piquelife.com/drestima.TROSCRIPTIONS - There's a completely new way to optimize your health. Give it a try at https://troscriptions.com/BETTER or enter BETTER at checkout for 10% off your first order.JUST THRIVE HEALTH - Take the Just Thrive FEEL BETTER challenge today, and save 20% on your first order. Go to https://justthrivehealth.com/better and use the code BETTER to see the difference for yourself or get a full product refund, no questions asked.AGZ - If you're ready to turn down the stress and focus on the rest, head to https://drinkag1.com/STEPHANIE to get a FREE Frother with your first purchase of AGZ.LVLUP - Ultimate GI Repair combines powerful gut-healing peptides with gut-nourishing naturals to soothe your changing digestion. Go to https://lvluphealth.com/DRSTEPHANIE and use code DRSTEPHANIE for 15% off. P.S. When you're ready, here are a two ways I can help you:Subscribe: The Mini Pause — My weekly newsletter packed with the most actionable, evidence-based tools for women 40+ to thrive in midlife.Build Muscle: LIFT — My progressive strength training program designed for women in midlife. Form-focused, joint-friendly, and built for real results. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.