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AD FREE DOPEY at www.patreon.com/dopeypodcast This week on Dopey! We start wrapping up 2025 with a candid check-in: feeling under the weather amid a family stomach virus, craving a Sopranos binge, and doubting plans for "Five Days of Dopey" in January (Wednesday/Thursday shows likely intermittent—send opinions to dopeypodcast@gmail.com). We share the ultimate post-Christmas blues remedy: a trip to Elizabeth A. Morton National Wildlife Refuge in Sag Harbor, NY, where chickadees, titmice, and woodpeckers eat seeds straight from your hand in the snowy quiet—described as magical, healing, and the true "opposite of addiction."Dave addresses backlash from replaying Nick Reiner episodes (including harsh comments like "Narcissist Grifter" and "Exploitative Jew"), explains his intent to share old conversations without commentary, notes new listeners discovered Dopey through them, and mentions turning down media interviews. He plugs ad-free listening on Patreon (patreon.com/dopeypodcast) and urges positive iTunes reviews.Listener Emails (Oldies Read Aloud)Wendy: Proposes a dedicated recovery-focused social media platform to avoid bans for "junky" content.James D. Hart: Highlights interracial bands like Prince and the Revolution (inspired by Sly & the Family Stone), Jimi Hendrix Experience, and Smashing Pumpkins.Christy Adams: Celebrates 3 years clean, praises an older neuroscience/meth/GLP-1 episode, and misses the original Dave/Chris dynamic.Stickers or socks for anyone whose email/voicemail gets read—email dopeypodcast@gmail.com.Main Feature: Classic Darrell Hammond Interview Replay (2017) The legendary SNL cast member (longest-tenured before Keenan) gets raw about:SNL highs/lows, iconic impressions (Clinton, Connery), working with Lorne Michaels, and celebrity encounters.Childhood trauma and abuse, flashbacks, and blaming himself to protect the idea of parental love.Alcoholism starting at 14 (first beers felt like "the world turning from black-and-white to color").Self-harm as a "problem solver" and crisis creator during prolific periods.Wild Harlem crack house story (mistaken for a cop, defended as "that motherfucker old TV," spotting the St. Francis Prayer on the wall).Multiple relapses, including after a sponsor's suicide.Stroke-ward epiphany that finally led to lasting sobriety—seeing patients struggle to speak inspired desperation for change.Recovery tools: St. Francis (11th Step) Prayer, connection with others, cognitive therapy, yoga, meetings, and the "law of threes" (expect ⅓ great days, ⅓ okay, ⅓ rough).Wrap-Up Dave re-reads old Spotify comments on the Hammond episode (debates over "This or That," therapy questions, possum facts, etc.) and closes with his heartfelt acoustic cover of "Good So Bad"—the song from the first Dopey episode he heard that inspired him to get clean.All that and more on this weeks installment of that good old Dopey Replay Show! Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
Legendary Life | Transform Your Body, Upgrade Your Health & Live Your Best Life
Most men lose muscle not just because of aging, but because they're no longer training for their 40+body . In Part 1 of this series, Ted reframed the entire conversation around aging by explaining why longevity isn't about living longer, but about extending healthspan. In Part 2, he challenged the dangerous belief that weight loss automatically equals health, breaking down why metabolic health matters far more than what the scale says In part 3, Ted breaks down how men over 40 should train to preserve and build muscle, protect their joints, and avoid the aches and injuries that derail progress. You'll learn the core principles behind Ted's Maximum Muscle Activation approach — a smarter, time-efficient way to stimulate muscle, work around limitations, and get results in under two hours per week. If your body feels like it's holding you back, this episode is for you. Listen now! You'll learn: Why muscle is the most important longevity organ in the body How muscle loss leads to frailty, loss of independence, and early death The minimum effective dose of strength training to maintain muscle How training close to failure drives muscle preservation and growth What Ted discusses in this episode: (00:00) Introduction (02:24) Understanding Muscle Loss and Aging (03:17) The Importance of Muscle for Longevity (04:56) Sarcopenia: The Age-Related Muscle Loss (10:46) Training Around Injuries (11:52) Strength Training Principles (21:46) Power Training and Mobility (24:58) GLP-1 Drugs and Muscle Loss (26:20) Conclusion and Next Steps
I am delighted to reconnect with Dr. Jason Fung today. We last connected in October 2020 for Episode 121. Dr. Fung is a nephrologist and a prominent figure in the intermittent fasting and low-carb space. He has made significant contributions as a founding member of The Fasting Method, providing evidence-based guidance on weight loss and blood glucose management through low-carb diets and intermittent fasting. He has written several books, including The Obesity Code, The Complete Guide to Fasting, The Diabetes Code, and The Cancer Code. In our discussion today, we look at the forecast for metabolic health in 2024, exploring how the growth of the diabetes population relates to the effects of the pandemic and addressing the conflict of interest with organizations like the ADA and registered dieticians. Dr. Fung shares some of his biggest frustrations, including the shallow and myopic thinking amongst those focusing on calories in and calories out, and we get into various facets of metabolic health, from the nuanced influences of gender, puberty, perimenopause, and menopause to hedonistic eating, sarcopenia, bio-individuality, and therapeutic fasting. Dr. Fung also shares his perspective on GLP-1s, shiftwork, supplements, and more. Join us for valuable insights on various aspects of metabolic health and how they impact our well-being. IN THIS EPISODE YOU WILL LEARN How the influence of food companies has led dieticians and diabetes associations to focus on moderation instead of a balanced diet Dr. Fung shares his frustration with the lack of progress in addressing the diabetes issue How hormones impact weight gain and hunger Why does focusing on calories in and out not provide the solution to weight loss? How intermittent fasting can help to control hormonal issues How middle-aged women need to find balance when fasting to maintain muscle mass and avoid sarcopenia How intermittent fasting can lead to increased strength despite losing muscle mass What causes shift workers to gain weight? The potential drawbacks of using GLP-1 drugs for weight loss Why magnesium deficiency is a common problem in modern society Connect with Cynthia Thurlow Follow on X, Instagram & LinkedIn Check out Cynthia's website Submit your questions to support@cynthiathurlow.com Join other like-minded women in a supportive, nurturing community (The Midlife Pause/Cynthia Thurlow) Cynthia's Menopause Gut Book is on presale now! Cynthia's Intermittent Fasting Transformation Book The Midlife Pause supplement line Connect with Dr. Jason Fung Website Twitter and YouTube The Fasting Method Dr. Fung's books Previous Episode Featuring Dr. Jason Fung Ep. 121 – The Truth About Diabetes, Kidney Disease and Insulin Resistance with Dr. Jason Fung
Anecdotal stories suggesting that weight-loss drugs can help people shake long-standing addictions have been spreading fast in the past few years, through online forums, weight-loss clinics and news headlines. And now, clinical data are starting to back them up.Over a dozen randomized clinical studies testing whether GLP-1 drugs like Ozempic can suppress addiction are now under way, and neuroscientists are working out how these weight-loss drugs act on brain regions that control craving, reward and motivation.Scientists warn that the research is still in its early stages, but some researchers and physicians are excited, as no truly new class of addiction medicine has won approval from regulators in decades.This is an audio version of our Feature: Will blockbuster obesity drugs revolutionize addiction treatment? Hosted on Acast. See acast.com/privacy for more information.
In this episode of The Best You Podcast, Nick sits down with Dr. Will Bulsiewicz—New York Times bestselling author, award-winning gastroenterologist, founder of 38TERA, and one of the world's leading voices in gut health. Dr. B is passionate about helping people understand the foundational role their gut plays in both everyday health and long-term disease prevention.We dive deep into the microbiome, the gut lining, the immune system, and how they're all connected. Dr. B explains how conditions like constipation, bloating, diarrhea, IBS, and more are often rooted in gut dysfunction—and most importantly, what to do about it.From how much fiber you should eat daily to how GLP-1s (like Ozempic and Wegovy) are affecting your gut, this conversation is packed with cutting-edge insight and practical takeaways.What You'll Learn:● What your gut microbiome is and why it matters for your entire body● How your gut lining affects immunity, inflammation, and long-term health● How many different plants to eat each week for optimal microbiome diversity● How much fiber Dr. B recommends daily (and why most of us fall short)● How GLP-1 drugs are impacting digestion and gut health● First steps to take if you're dealing with constipation, diarrhea, IBS, or general gut dysfunction
Full shownotes, transcript and resources here: https://soundbitesrd.com/302 The health risks of heavy drinking are well-established. But what about the health risks of light to moderate drinking? More people, especially the Gen Z population, are leaning toward moderation of alcohol intake rather than going completely dry, shifting the popular "Dry January" challenge toward more of a "Damp January" trend. While the role of alcohol in health-related outcomes is complex and nuanced, a new meta-analysis of 23 major studies from 2000 to 2024 found that light-to-moderate drinking carries the same – or in some cases lower – risk of death compared to abstaining, while lifestyle factors like diet and exercise play a huge role in outcomes. Likewise, a new report published in September sheds light on alcohol and health including WHO data showing reductions in alcohol-related morbidity and mortality with many countries on track to meet targets for reducing harmful drinking. Tune in to this episode with guest Jennifer Tujague, MPH, to learn about: · the different and conflicting reports on alcohol intake and recommendations · the research on alcohol consumption and health · how moderation is defined · different drinking patterns and associated risks · combined effects of obesity and alcohol · alcohol and weight · GLP-1s and alcohol · Non-alcoholic beverages · The Damp January trend · resources for health professionals and the public
If YOU'RE ready to make real, sustainable change in your life, jump on a free call with us - https://physiquedevelopment.typeform.com/to/ToP9TYLEToday's episode is all about fitness and wellness trends—what took over in 2025 and where things are likely headed in 2026.Sue and Alex unpack the patterns they've seen gain momentum, why trends aren't inherently good or bad, and how marketing often oversimplifies solutions that are far more nuanced in real life.They start by breaking down major 2025 trends—from the shift away from HIIT and bootcamps toward Pilates and community-driven movement, to the rise of weighted vests, endurance events like Hyrox-style racing, and wearable trackers.From there, they look ahead to 2026 predictions, including an increased emphasis on sleep tracking, AI-powered upgrades, new approaches to walking ("Japanese walking," anyone?), continued expansion of community-based fitness, and evolving conversations around GLP-1 medications.The takeaway? The next big thing isn't always your next big thing. This episode will help you think critically about trends, avoid getting pulled in every direction, and choose what actually aligns with your goals.We'll see you in the New Year!Have questions or comments for the podcast? Drop them here - https://forms.gle/AEu5vMKNLDfmc24M7Check out our FREE 4-Week Glute Program - https://go.physiquedevelopment.com/freegluteprogram701788And keep the gains rolling with 12 MORE weeks of glute growth (use code POD at checkout for $25 off!) - https://train.physiquedevelopment.com/workout-plans/963551As always, it is our goal not only to supply you, the listener, with valuable insights on the topics or questions but also to plant some seeds for further research and thought. Be sure to like and subscribe and leave us a review wherever you're listening if you loved this episode!Timestamps:(0:00) Today's topic(1:57) Trends we saw in 2025(2:10) Trend #1(5:07) Trend #2(9:56) Trend #3(12:04) Trend #4(18:57) Trend #5(20:01) Trend #6(21:58) Trend #7(23:46) Predictions for 2026(24:05) Prediction #1(28:40) Prediction #2(29:13) Prediction #3(30:17) Prediction #4(32:36) Prediction #5 (a hot take??)(34:19) Prediction #6(37:10) Prediction #7(38:09) Prediction #8(42:44) Wrap-upAdditional Resources:Weighted Vests: Health Hack or All Hype?? (the REAL science) - https://pod.fo/e/34970dFollow us on Instagram:Coach Alex - https://www.instagram.com/alexbush__Coach Sue - https://www.instagram.com/suegainzPhysique Development - https://www.instagram.com/physiquedevelopment_Physique Development Podcast - https://www.instagram.com/physiquedevelopmentpodcast----Produced by: David Margittai | In Post MediaWebsite: https://www.inpostmedia.comEmail: david@inpostmedia.com© 2025, Physique Development LLC. All rights reserved.
This podcast is brought to you by Outcomes Rocket, your exclusive healthcare marketing agency. Learn how to accelerate your growth by going to outcomesrocket.com What if AI could not only track your health but truly care for you when your doctor isn't around? In this episode, Dr. Jennie Luna, Founder and CEO of NuVee, discusses creating an AI health companion called Koa, designed to provide empathy and support to patients between doctor visits. She explains the difference between GLP-1 and GIP+GLP-1 medications for diabetes and obesity. Dr. Luna also shares her journey in healthcare, discussing how AI is transforming the industry and the need for more compassionate care in managing chronic conditions, such as obesity. She discusses how technology can bridge the gap in patient care, providing personalized support where it's needed most. Tune in to discover how AI is transforming the future of healthcare and enabling patients to live healthier, more connected lives Resources Connect with and follow Dr. Jennie Luna on LinkedIn. Follow NuVee on LinkedIn and discover their website!
Send a Text Message. Please include your name and email so we can answer you! Please note, this does not subscribe you to our email list, it's just to answer if you have a questions for us. In this special end-of-year episode, I'm doing something I've never done before: slowing down to reflect on the moments, lessons, and people who shaped this year—and sharing a glimpse of what's coming in 2026.From the evolution of the 30/30 community and the launch of new programs to personal growth, nervous system work, and learning how to protect my own energy, this episode is an honest look at how the year changed me as both a physician and a person.I also walk through the big themes I'm feeling pulled toward next and end with a heartfelt gratitude list that reminded me just how grateful I am for the village that makes any of this possibleIf you've been part of this community in any way, this episode is my thank-you letter to you. (And if you're curious about what's coming in 2026, stick around!)Ways to work with me:The 30/30 Program // Season 1 Behind the Curtain // Season 2 Behind the CurtainBeyond the Scale (A 30/30 Retreat) // Clinician Social Accelerator // The Body Intelligence BlueprintAudio Stamps00:28 - Reflecting on 2025's guiding words: connection and calm after an overwhelming 202402:23 - Three rounds of 30/30 showed how people thrive with community and accountability04:33 - Behind the Curtain podcast launch and 21 incredible podcast guests this year covering addiction, grief, ADHD, skin health, and more11:16 - Building the Social Media Accelerator and Female Founders Accelerator to help other physicians grow strong, independent practices13:07 - Learning to regulate energy through intentional family time, emotional eating work, sound baths, and prioritizing whole-based foods15:20 - What's coming in 2026: in-person retreats, genetics work, and more focused programming19:28 - Gratitude list: A heartfelt thank you to the extensive village that makes this work possibleAll of the information on this podcast is for general informational purposes only. Please talk to your physician and medical team about what is right for you. No medical advice is being on this podcast. If you live in Indiana or Illinois and want to work with doctor Matthea Rentea, you can find out more on www.RenteaClinic.com Not Sure Where to Start With the Podcast? I've Got You.Get my free Podcast Roadmap—a simple guide to help you find the episodes that matter most to your journey. Whether you're on GLP-1s, navigating plateaus, or just starting out, there's something here for you.Support the show
Join Physique University to get fat loss coaching, community support, and access to the "Get Lean in 45 Days" workshop on January 20th, a complete framework for executing a short, aggressive, muscle-sparing cut that actually works:https://witsandweights.com/physique--Every January, millions start cutting calories. By March, most have quit... frustrated, tired, and no leaner than before. The problem isn't discipline. It's that they're trying to diet their way into a body they never built.Learn why muscle is an asset while cutting is just maintenance, how chronic dieting destroys your metabolism and body composition over time, and why people who build muscle first end up needing to diet less often for the rest of their lives. Discover the structural advantage that strength training provides, not just for how you look, but for glucose disposal, nutrient partitioning, and long-term metabolic health.Whether you're stuck in the yo-yo dieting cycle, considering GLP-1 medications, or simply want to lose fat without grinding through months of restriction, this episode gives you a step-by-step framework for designing a muscle-first year.Plus, learn about the Mini-Cut Accelerator, a counterintuitive approach that lets you lose fat faster while protecting more muscle.Episode Resources:Join Physique University to prep for the "Get Lean in 45 Days" workshop on January 20: https://witsandweights.com/physiqueTry Fitness Lab AI-powered coaching for 20% off through January 2nd: https://witsandweights.com/appTimestamps:0:00 - Why your 2026 fat loss goal will probably fail unless you do THIS 2:23 - The cutting-first trap 5:45 - How muscle improves metabolism, insulin sensitivity, and nutrient partitioning 12:20 - Why short cuts beat long diets for body recomp 17:02 - How to design 2026 for a muscle-first approach 24:10 - The Mini-Cut Accelerator to lose fat faster without losing muscleSupport the show
In this episode, Angela sits down with endocrinologist Dr. Rocio Salas-Whalen, MD to break down the biggest myths around GLP-1 medications, midlife weight gain, and perimenopause - and to explain how women can protect muscle, metabolism, and long-term health. Rocio explains how oestrogen decline and stress drive visceral belly fat, why you can have a normal BMI yet high visceral fat and low muscle, and why body composition matters far more than the scales. She also clarifies who GLP-1s are truly for, why microdosing “for wellness” is unsafe, and how to use these medications without losing muscle or bone. They also explore the psychological side of lifelong food noise, binge eating, and why GLP-1s can make sustainable lifestyle change finally feel possible. WHAT YOU'LL LEARN • How oestrogen decline changes fat distribution in midlife • Why “skinny fat” and sarcopenic obesity are often missed with BMI • How stress and cortisol contribute to midlife weight gain • Who is genuinely suited to GLP-1 therapy • How to preserve muscle and bone while on treatment • The mental health benefits of reducing lifelong food noise • Why safe dosing and body composition tracking are essential Timestamps 0:00 Intro & GLP-1 Myths 4:30 Oestrogen decline, perimenopause & new visceral belly fat 10:20 Stress, cortisol, midlife pressure & weight gain 15:05 “Skinny fat”, sarcopenic obesity & why BMI fails women 21:10 Muscle loss, slowed metabolism & weight loss resistance 27:40 Who GLP-1s are for: guidelines vs real-world practice 34:15 The truth about microdosing GLP-1s for “wellness” 40:05 Type 1 vs type 2 diabetes, insulin needs & GLP-1s 45:50 Inflammation, visceral fat & joint pain relief 52:00 Side effects, risks & how to avoid muscle/bone loss 58:10 Compounded GLP-1s, safety concerns & regulation 1:04:00 Psychology of rapid weight loss & identity change VALUABLE RESOURCES A BIG thank you to our sponsors who make the show possible: • Hormone Harmony – Go to https://lvluphealth.com/angela | Use code ANGELA for an exclusive 15% off • Beam Minerals – Go to https://beamminerals.com/angela | Use code ANGELA for an exclusive discount • Ozlo Sleepbuds® – Go to https://ozlosleep.com/angela | Use code ANGELA for your exclusive discount ABOUT THE GUEST Dr Rocio Salas-Whalen, MD is a double board-certified endocrinologist and obesity medicine specialist known for her evidence-based, body-composition-focused approach to metabolic health. She is the author of Waitlists, a practical guide to safe and effective GLP-1 use, and is widely recognised for her clear, compassionate education around hormones, midlife weight gain, and modern obesity treatment. Website & Book: https://weightlessthebook.com/ Instagram: https://www.instagram.com/drsalaswhalen/
This week on Fat Science, Dr. Emily Cooper, Mark Wright, and Andrea Taylor talk with pediatric eating disorder specialist Dr. Julie O'Toole (Kartini Clinic) and pediatric obesity expert Dr. Evan Nadler about what childhood obesity really is: a biologic, metabolic disease—not a willpower problem and not a failure of parenting.They explore how excess weight, constant hunger, and disordered eating in kids are often signs of underlying metabolic dysfunction and genetics—and why the old “eat less, move more” advice can do real harm, especially when children are shamed or restricted in the name of “health.”Key Questions AnsweredWhy is childhood obesity a metabolic disease, not a behavior problem?How are obesity and eating disorders deeply connected instead of opposite extremes?What role do GLP-1 medications play in children—and how do we protect against under-fueling?When should parents suspect genetic drivers like hyperphagia or MC4 mutations?How can medical treatment for obesity actually reduce disordered eating behaviors?When does excess weight become a medical issue requiring metabolic evaluation—not another diet?Key TakeawaysWeight is a symptom. Childhood obesity is often a sign of metabolic dysfunction, not overeating.Obesity & eating disorders overlap. Restriction can trigger disordered eating; disordered eating can worsen obesity.“Eat less, move more” harms. Shame-based approaches delay treatment and increase risk of eating disorders.GLP-1s work metabolically, not just through appetite suppression. Kids still need consistent fueling.Genetics matter. Single-gene differences can drive severe childhood hunger & rapid weight gain.Not treating is harm. Avoiding obesity care violates first, do no harm.Dr. Cooper's Actionable TipsIf your child is gaining weight or constantly hungry, request metabolic labs (insulin, glucose, lipids, liver, hormones).If the doctor only says “eat less, move more,” ask: “How are we evaluating metabolism and genetics?”On GLP-1s? Monitor for under-fueling (skipped meals, low energy, food anxiety) and intervene promptly.Notable Quote“Not treating childhood obesity is doing harm. It's a disease, not a lifestyle choice.” — Dr. Evan NadlerLinks & ResourcesPodcast Home: Fat Science WebsiteEpisodes & Show Archive: Cooper Center Podcast PageEducation & Metabolic Resources: coopermetabolic.com/resourcesSubmit a Show Question: questions@fatsciencepodcast.comEmail Dr. Cooper Directly: dr.c@fatsciencepodcast.comConnect with Our GuestsDr. Evan P. Nadler, MD, MBA – Founder, ProCare Consultants & ProCare TeleHealthWebsite: obesityexplained.comYouTube Channel: Obesity ExplainedDr. Julie K. O'Toole, M.D., M.P.H. – Chief Medical Officer & Founder, Kartini ClinicWebsite: kartiniclinic.comBooks: amazon.com/author/julieotoole*Fat Science breaks diet myths and advances the science of real metabolic health. No diets. No agendas. Just science that makes you feel better. This episode is informational only and not medical advice.
Feeling stuck? If your GLP-1 weight loss has slowed down or stopped, you're not alone and it does not mean the medication stopped working. In this episode, Gianna walks you step-by-step through her checklist for stalls, which she uses to help GLP-1 clients restart progress without panic, restriction, or jumping doses.Listen to learn how to fuel properly, protect your metabolism, check your consistency, and adjust habits so your results return- calmly and confidently. ✨ The GLP-1 Circle Membership is opening the doors soon, available for all GLP-1 users, it's your hub for dietitian/personal trainer support on your GLP-1 journey for only $99/month. Get first dibs on membership spots here: Join the waitlist
SummaryIn this episode, Chase and Chris dive into your top questions from the week — and the answers might surprise you. They talk about what really happens when you're under-eating for days, whether it's possible to build muscle and lose fat at the same time, and if eating things like pickles is really “too much sodium.”They also cover how much muscle actually increases strength (hint: it's not as simple as it sounds) and who really needs to work out twice a day. If you've ever felt confused by mixed messages in the fitness world, this Q&A episode will clear things up in a real, no-BS way.Chapters(00:00) GLP-1 Buzzwords and BS Marketing Tactics(08:26) What Happens If You Undereat for Days?(11:10) Can You Burn Fat and Build Muscle at the Same Time?(16:33) Are Pickles Bad for You? The Truth About Sodium Intake(19:40) Does Gaining One Pound of Muscle Make You Stronger?(21:32) How Do People Work Out Twice a Day Without Overtraining?(27:47) Masterclass & 2026 Challenge Sneak PeekSUBMIT YOUR QUESTIONS to be answered on the show: https://forms.gle/B6bpTBDYnDcbUkeD7How to Connect with Us:Chase's Instagram: https://www.instagram.com/changing_chase/Chris' Instagram: https://www.instagram.com/conquer_fitness2021/Facebook Group: https://www.facebook.com/groups/665770984678334/Interested in 1:1 Coaching: https://conquerfitnessandnutrition.com/1on1-coachingJoin The Fit Fam Collective: https://conquerfitnessandnutrition.com/fit-fam-collective
Welcome to the Mind Muscle Connection Podcast!In this solo episode, I dive into the Fat Loss Misconceptions To Leave Behind in 2026From willpower misconceptions to calorie slashing gone wrong, I break down why some of the most common advice you hear about fat loss might actually be the thing holding you back. We'll cover GLP-1s, diet quality, recovery tradeoffs, meal timing, and more, plus what to do instead if you want results that actually last.If you've been spinning your wheels or feeling stuck in your fat loss phase, this episode will give you a more realistic, sustainable lens to work from!Let's talk about:IntroductionFat loss misconceptions#1 Lack of willpower#2 Not eating enough#3 As long as calories are in check, you're fine#4 Tracking automatically means fat loss#5 Meal timingFollow me on Instagram for more information and education: @jeffhoehn_FREE 30 Min Strategy Call: HEREBody Recomp Checklist 2.0 HERENutrition Periodization Masterclass: HEREHow You Can Work With Me?: HERECoaching application: HERE
Send us a message with this link, we would love to hear from you. Standard message rates may apply. Oral Wegovy is officially FDA approved — but what does that actually mean for patients? In this episode of Your Checkup, we break down the December 2025 approval of oral semaglutide 25 mg for chronic weight management, who qualifies, how it works, and how effective it really is. We review the clinical trial data behind the approval, including expected weight loss, common side effects, and long-term expectations, and explain how oral Wegovy compares to injectable GLP-1 medications. We also tackle common misconceptions, dosing and lifestyle considerations, and the very real challenges of cost and insurance coverage. If you've heard the headlines and want the facts — without hype — this episode is for you. Check out our new graphics. Thank you, Vantage Design Works. Check out our website, you can send us an email, yourcheckuppod@gmail.com. Check out our website, you can find us on Instagram, share us with a friend or a neighbor. But most importantly, stay healthy, my friends.Support the showProduction and Content: Edward Delesky, MD, DABOM & Nicole Aruffo, RN Artwork Rebrand and Avatars: Vantage Design Works (Vanessa Jones) Website: https://www.vantagedesignworks.com/ Instagram: https://www.instagram.com/vantagedesignworks?igsh=aHRuOW93dmxuOG9m&utm_source=qr Original Artwork Concept: Olivia Pawlowski
What changes when an eating disorder has been part of someone's life for 10, 20, 30, even 40+ years? In this conversation, I'm joined again by my friend and longtime collaborator Jaren Soloff, RD, IBCLC, the founder of Whole Women Nutrition. Together, we talk about why nutrition work looks different in long-term eating disorders, and why the starting point is almost always the same: safety. Jaren shares how decades of reinforcement can make symptoms look “functional” on the surface, while the eating disorder quietly shapes identity, routines, and self-worth. We explore the common pattern of minimizing, the fear that can spike when restriction loosens, and the tender reality that for many people, the eating disorder has served as protection, especially in the context of criticism, attachment wounds, body-based judgment, and the impossible standards placed on women across the lifespan. We also get practical. Jaren walks through what it can look like to make food feel safer through small, doable steps, including DBT-informed tools, sensory supports, and intentionally planned “after-meal” structure that helps the nervous system ride out discomfort without snapping back to restriction. If breakfast feels impossible, or discomfort after eating feels like a dealbreaker, this episode offers compassionate, concrete ways to build tolerance and trust, slowly and steadily. Finally, we talk about the midlife reality so many people face: body changes through perimenopause and menopause, and the way those changes can collide with long-standing eating disorder beliefs. Jaren explains why metabolism may shift with long-term restriction and aging, how loss of lean muscle mass can affect energy needs and health, and why increased fat storage in midlife can be an adaptive, protective process for bone health. We also name the risks of GLP-1 medications for people with eating disorders, including concerns about appetite suppression and the potential for additional lean muscle loss, especially for women in perimenopause and menopause. If you have felt “broken” because your body doesn't respond the way it once did, or if you've carried an eating disorder for decades and wonder whether change is still possible, this conversation offers a grounded, compassionate path forward. You deserve care that moves at your pace, and support that treats safety as the foundation, not an afterthought. In this episode, we cover We discuss why long-term eating disorders require a different nutrition framework, how safety often sits at the center of recovery work, and why minimizing can keep patterns in place even when someone appears to be “functioning.” We talk about learning to tolerate discomfort after eating, building self-soothing skills, and using DBT-informed, sensory-based strategies to create new neural pathways. We explore perimenopause and menopause, including changes in estrogen, lean muscle mass, metabolism, and body fat distribution, and we name how ageism and sexism shape body fear in midlife. We also discuss GLP-1 medications and why they can be especially risky in the context of eating disorders. About Jaren Soloff, RD, IBCLC Jaren Soloff is a registered dietitian and international board-certified lactation consultant. She is the founder of Whole Women Nutrition, where she provides nutrition counseling and lactation support for adolescent girls and adult women, and supports families in raising competent, intuitive eaters. Jaren brings both professional experience and the wisdom of her own recovery journey to her work, with a steady emphasis on compassion, collaboration, and safety. Related Episodes Orthorexia, Quasi-Recovery, & Lifelong Eating Disorder Struggles with Dr. Lara Zibarras @drlarazib on Apple & Spotify. Navigating a Long-Term Eating Disorder on Apple & Spotify. Why Eating Disorder Recovery Feels Unsafe: Facing Ambivalence in Long-Term Struggles on Apple & Spotify. Pregnancy, Postpartum, and Eating Disorder Recovery With Jaren Soloff, RD on Apple and Spotify. Connect with Jaren Website: WholeWomenNutrition.com Instagram: @wholewomennutrition
“It is more dangerous to your health not to have muscle mass than to have excess body fat,” explains Rocío Salas-Whalen, M.D. Salas-Whalen, a board-certified Endocrinologist, Obesity Medicine specialist, and widely recognized as one of the earliest adopters of GLP-1 therapies in the United States, joins us today to explain how GLP-1s work, who truly benefits, and the crucial steps you need to take to protect your metabolism along the way. - How to know if GLP-1s are right for you (~4:00) - Are there longevity benefits of GLP-1s? (~5:10) - Types of body composition profiles (~7:00) - How to protect your muscle mass on GLP-1s (~8:50) - Protein recommendations (~12:00) - Common mistakes (~13:00) - Conversations to have with your provider (~14:25) - Getting off GLP-1s (~18:05) - The most important steps to build muscle (~19:30) - HRT + GLP-1s (~21:30) - Who should not take GLP-1s (~25:05) - The importance of lifestyle (~27:55) - The internal gains of GLP-1s (~29:45) - The mindset needed for long-term success (~31:35) - GLP-1s for minors? (~37:55) - The future of this space (~42:00) Referenced in the episode: - Follow Salas-Whalen on Instagram (@drsalaswhalen) - Pick up her book, Weightless (https://weightlessthebook.com/) - Work with her (https://www.nyendocrinology.com/home) - Liraglutide in mild to moderate Alzheimer's disease (https://www.nature.com/articles/s41591-025-04106-7) We hope you enjoy this episode, and feel free to watch the full video on YouTube! Whether it's an article or podcast, we want to know what we can do to help here at mindbodygreen. Let us know at: podcast@mindbodygreen.com. Learn more about your ad choices. Visit megaphone.fm/adchoices
In this episode of The Milk Check, Ted Jacoby III welcomes Lloyd Metzger and TJ Jacoby of Valley Queen Cheese Company for a deep dive into the science, functionality and future of dairy proteins. The conversation starts at the molecular level – the difference between casein and whey – and builds toward the real-world implications for product developers, processors and nutrition brands. We cover: Why casein is built to carry calcium (and whey isn’t) How heat and pH change protein behavior Fast versus slow digestion and why both matter The role of whey protein in muscle maintenance, aging and GLP-1 nutrition What pro cream really is and why its value may be underestimated Why cellular agriculture is more niche than threat If you work in dairy, food formulation or nutrition, this is a protein conversation worth digesting. Got questions? We'd love to hear them. Submit below, and we might answer it on the show. Ask The Milk Check TMC-Intro-final[00:00:00]Ted Jacoby III: Hi everybody, and thank you for joining us today for this very special recording of the Milk Check Podcast. Today, our topic is: what is the future of dairy proteins? And we have two very special guests. The first is Lloyd Metzger, VP of Quality and Technical Services for Valley Queen Cheese Company, and formerly Professor of Dairy Science at South Dakota State University. And the second, particularly special to me, is my son TJ Jacoby, Whey Technologist for Valley Queen. A South Dakota State graduate. Someone who has been interested in dairy proteins since his first biology class in high school. Guys, thank you for joining us today and welcome to The Milk Check. Lloyd Metzger: Glad to be here. TJ Jacoby: Good to be on, Dad. Ted Jacoby III: It’s December 18th, 2025. Milk production in the US is up 4%. Milk production in Europe is up something similar. Milk production in New Zealand is up. Milk production in Argentina is up. We are definitely in an [00:01:00] environment today where the supply of milk and dairy is overwhelming demand, at least for the moment. Cheese prices are near historical lows. Butter prices are near historical lows. Nonfat milk, skim milk powder prices are on the low end of the range. This market is a market that feels heavy, and I think most people out there would say, it almost feels like even though we’re at lows, we may actually go lower before we go higher. And yet, on the other hand, there are whey proteins, Josh, if I’m not mistaken, whey proteins just hit historical highs. Josh White: Maybe the highest prices we’ve ever seen for whey protein isolate and WPC 80. Ted Jacoby III: So, we have an environment where the demand on the protein side is extremely strong, and the trends on protein consumption are extremely strong and really feel like they’re gonna be around for quite some time. We’ve got baby boomers retiring and whether it’s because of GLP-1s or it’s just a general knowledge and understanding of what human nutritional needs are as people age, they know that they need more protein in their [00:02:00] diet. So, it begs the question: what is going on with dairy proteins and whey proteins and how is this going to evolve in such a unique market where demand is so strong for protein right now? And so, I’m gonna ask the question first. What’s the difference at a molecular level between whey proteins and milk proteins? Because when we’re in an environment like we are now, where you’ve got the demand really, really high, you also have a market that’s gonna start looking for alternatives, simply because prices are so high. What is the difference between milk proteins in general and whey protein specifically? Lloyd Metzger: It’s important to talk about from a functional perspective how the proteins are different. I’m sure we’ll get into the nutritional differences between those proteins as well. It’s important to understand what’s driving those differences in functional characteristics. And it’s really all about calcium. The casein system is designed to carry calcium. The whey protein system is not designed to carry calcium. That differentiates the two groups of [00:03:00] proteins and makes their properties very different. TJ Jacoby: I’ll explain it like this. Milk proteins, there’s two classes of proteins, right? There’s casein and then there’s whey. The casein is used to make cheese, and then the whey protein is what comes off. So, the whey protein is everything that is not used to make cheese. So, the reason why casein proteins works so well for cheese because those proteins like to fall together in these spheres, they like to stick to one another. They like to stick to one another ’cause they have certain groups that latch onto the calcium and then they bridge with phosphate. When they do, they have multiple proteins, different types of casein proteins that bridge together with phosphate and then based on their repulsion forces, they stick together. Calcium and phosphates really help it stick when we make cheese. The outside of that casein, micelle, that ball, when we make cheese, that outside is stripped off, it becomes hydrophobic, and that causes those spheres to stick together. That’s a huge functional property of casein. Whey [00:04:00] protein is the opposite. Whey protein is really hydrophillic. It’s very polar. So, they like to float around in solution and stay floating around in solution. And they don’t like casein. It likes to stay separate from casein. And so, when you make cheese, it readily is released into the whey stream because it likes to stick with the water. In the same way, those kind of stick together with these sulfur groups. But when you heat it up, they unfold. And when they unfold, now there’s certain reactions that can take place. So, those are the two major differences between casein and whey. Lloyd, what did I miss? Lloyd Metzger: I would try to simplify it a little bit. The difference between casein and whey protein is casein is what’s trapped when we make cheese. And whey protein is the soluble protein that’s left over in the water phase of cheese. Cheese making is a dehydration process. We concentrate the fat and protein that’s in milk, the casein version of protein in milk. But you gotta look at the properties of those two [00:05:00] systems and the groups of protein. So, the casein protein is actually really stable to heat, but it is not stable to pH. So, casein will always coagulate at low pH. So, you lower the pH of milk, you get a yogurt-like product. That’s all the casein that’s coming out of the system. Whey proteins don’t mind a low pH, and they’ll stay soluble at a wide range of pH. But now, when you get to temperature, the complete opposite happens. Casein can handle super high temperatures and be very stable. Whey proteins can not handle high temperature at all, they start to gel. I think it’s important to look at the two different groups. Now you get into the functional differences between those two and the very different properties you have between those. Lloyd Metzger: That’s why you get all these products that are very different from each other. Why cheese is so much different than whey protein. And then you have these dairy products that are a combination that have the two together. So like when we make yogurt, we end up with the two products together and get this property that’s partway in between the two proteins. Ted Jacoby III: [00:06:00] Based on what you’re describing, when we’re talking about milk proteins, MPC 80, for example, there’s a higher level of calcium, I take it in milk proteins than compared to whey proteins. Is that true? Lloyd Metzger: Absolutely, but let’s remind everybody: milk protein is both casein and whey protein together at the normal ratio that’s in milk. So, of the protein, 80% is casein, 20% is whey protein. So, when you say milk protein, you’re actually meaning 80% casein and 20% whey protein. Now, when we talk about cheese or casein, we’re basically a hundred percent casein and 0% whey protein. Now, when we talk about whey protein, we’re essentially a 100% whey protein, no casein except for one fragment of casein that actually gets solubilized, as TJ described, and now actually becomes part of whey protein. Something that a lot of people don’t understand is that about 15% of what we call whey protein is actually a piece of casein that gets lost in the whey and now gets [00:07:00] captured and harvested in the whey protein manufacture process. But again, it’s important to remember milk protein is a 80 / 20 combination of casein and whey protein together. So, when you’re talking about milk protein, you’re actually talking about whey protein and casein together. Ted Jacoby III: It’s funny, I just learned something never really quite had my head around, and that’s that 80 / 20 ratio, that 80% of all the protein in milk is actually either alpha or beta casein. Correct? Lloyd Metzger: There’s actually four different casein fractions that are involved that make up that 80% of the total protein. Ted Jacoby III: Okay. The casein molecule isn’t really any bigger than most of the whey protein molecules, but they tend to clump together in those micelles. And so, they act as one big humongous mass compared to whey proteins. Correct? TJ Jacoby: Whey proteins may be collected like in pairs like two at a time, but casein proteins, there’s hundreds, right? Lloyd, that will just clump together. Thousands. TJ Jacoby: So, these spheres are absolutely massive protein complexes, but in fact there are a lot of little individual [00:08:00] proteins that make it up and they’re all bridged together with calcium and phosphate. Lloyd Metzger: It’s a packaging system that was designed to package up calcium and phosphorus. So, the whole casein system was designed by nature as a delivery vehicle for calcium and phosphorus, because calcium is not soluble by itself. Calcium phosphate is essentially rock. It’s the material that makes up eggshells. Think, think about a ground up eggshell that calcium phosphate complex is not soluble and it will sink to the bottom of your container of milk if you didn’t have the protein complex to hold it in solution. The analogy I use is it’s basically a kidney stone. Think about how much fun milking a cow would be if all the calcium and phosphorus was in the form of a kidney stone as you’re trying to milk the cow. All that calcium and phosphorus can be solubilized with the casein system and put it into solution and then make it so you can deliver that in a nutritional product. Ted Jacoby III: That makes perfect sense. That’s really cool. I think you guys also already touched on the differences in solubility as you were [00:09:00] describing the different proteins. But there’s differences in digestibility as well. What’s the source of that difference? TJ Jacoby: I’ll take this one. Returning back to the infant stage, I feel like we could set this up in light of why nature created these proteins. Dairy is the fundamental human food for infants. You have babies that can live up to a year off of just their mother’s milk. All the proteins that are found in there, those building blocks to grow an infant, can be boiled down to those two protein streams: whey protein and casein protein. The purpose of the casein protein for the infants is it’s fast acting. It’ll go right into the gut, and the gut is full of enzymes, but also really, really low pH, so low that it actually causes even those whey proteins to unfold. And It allows the stomach enzymes to break it up super, super fast and be absorbed. It’s considered one of the most bioavailable proteins known to man. It’s designed for that, that’s why nature created whey protein. Well, whey protein itself is also very nutritious. It has one of the highest concentrations of [00:10:00] essential amino acid, and the second highest known to man of branch-chain amino acids. That means it doesn’t have to be processed through the liver before it can be used by the human body. If your body’s actively using and consuming protein whey protein’s really good because it can be absorbed into your system and go right to the muscles. 33% of your muscle is branched chain amino acid. That’s what’s getting broken down while you’re working out. And then in the elderly, that’s what’s getting broken down that’s causing some muscle degeneration. Whey protein can help fortify that very quickly. However, all protein that is consumed in the body could also easily be processed through the liver with time. And so, if you have time, that’s where the casein comes into play. The casein, when it hits that acidic environment in the gut, it immediately clumps together. It actually creates cheese curds in the gut. And the reason why that’s so important is it slows down digestion so that slowly over time, that will be absorbed into the system. So it’s not [00:11:00] like a rush of energy right after the baby eats and then it goes away right away. Instead, it slows it down. The casein itself also likes to trap other nutrients. The casein in the gut will house the fat and the vitamins and the nutrients so that it’s slowly absorbed over the course of the next few hours before the baby’s next feeding. Ted Jacoby III: As a result of those digestibility differences, what are the differences in the amino acid profiles between casein and whey proteins? The body’s gonna need to break down most of that casein in order to absorb it. When the body breaks down that casein, what are the differences in the way that it absorbs some of those amino acid profiles and short-chain protein strands from the casein versus what’s readily bioavailable from the whey proteins? TJ Jacoby: Casein does not have the same percentage of those essential amino acids. It’s not as high, but it’s designed to be slow absorbing. Protein itself, it almost doesn’t matter the amino acid structure, as long as your body has enough of those vitamins and nutrients to absorb and to restructure it to [00:12:00] a different protein within the liver — that’s what your body needs. Most of us, the protein doesn’t have to be fast-acting. It’s not like our muscles are actively breaking down all the time. It can slowly be absorbed, be processed through the liver, and then used for almost any other function as long as we have all the vitamins and minerals that we need. Lloyd Metzger: Part of this huge shift we’re seeing in demand for protein, especially whey protein, this started 25, 30 years ago with bodybuilders and wanting to build muscle mass. And the realization that TJ mentioned: branch-chain amino acids are very important if you wanna rapidly put muscle mass on. It is also very important if you’re elderly or if you have sarcopenia where you’re starting to lose muscle mass. In those nutritional states, it’s really important to have high-level branch-chain amino acids, so you can put muscle on. Or if you’re on a GLP-1 medication where you’re not gonna be able to eat very much, you need a very efficient source of protein to build muscle mass. So there’s certain nutritional states where it is important to have branch-chain amino acids [00:13:00] and be able to get those from a protein like whey protein that has ’em at a very high level. But for the normal person, it’s not really all that relevant. You could get the protein you need from any protein that provides all the essential amino acids. Now, most plant proteins don’t do that. We’re talking about the difference between casein and whey protein. Both of them are an order of magnitude higher in nutritional quality than plant proteins because they have all the essential amino acids. And to TJ’s point, as long as you have the essential amino acids, the body can produce the non-essential amino acids from those essentials. Essential ones are amino acids the body can’t produce. You have to have those in the food you’re consuming to be able to produce the components you need. Josh White: We’ve got listeners from the dairy side of the equation and listeners from the utilization side that are making different products. And some of those customers are currently faced with the reality that a part of the equation for their adoption of whey proteins as an ingredient has shifted. The competition level’s very [00:14:00] high. They’re having more difficulty accessing some of it. And the price has changed quite a bit. And I think that when you’re talking about these products going into CPG applications as a lower inclusion rate ingredient, but with a lot of label power, being able to put whey protein, for instance, on that label, there’s several of them out there that are struggling to determine what the functional differences might be between the various dairy proteins. And what I’m afraid that is happening is some of these companies that are on the lower end of the value scale and can’t afford to keep up with all of the great products that are demanding whey protein or even milk protein, are gonnastart exploring alternatives outside of our space. and I think that we don’t want that, right? And what we’re seeing is this popularity of whey protein is driving a lot of customers for R&D projects to be asking us specifically for whey protein. And so help us understand what applications might make sense to use one, the other, or both. Lloyd Metzger: It completely depends on the product that [00:15:00] you’re after and the characteristics of the product that you want. Something like a beverage can go two different directions. So, if you’re gonna retort the beverage and put a lot of heat on it, you can’t do that with most whey proteins. They’re gonna gel. The most comparable protein to whey protein would be an egg protein. And everybody understands what happens when you heat eggs; they turn into a gel. So, whey proteins will happily do that. If you have a high enough concentration and you expose them to enough heat. Casein actually helps to protect whey protein from that coagulation. A lot of these high-protein beverages, they’re oftentimes a combination of casein and whey protein. They might alter the ratio a little bit from the 80 / 20. They might bump the whey protein up a little bit and have a 60 / 40 casein to whey protein. And so you’ll see ranges in that ratio of casein to whey protein, depending on the characteristics of the product that you’re actually after. The heat is a big piece of that. And then we go to pH as a big piece of what changes the functionality of casein to whey protein and makes you [00:16:00] change those ratios. Yogurt is another great example. You’ve got these super, super high-protein yogurts and a lot of cases they fortified with quite a bit of whey protein to be able to have more protein and still have the characteristics that you want in that product. In the protein bars, there’s all kinds of whey proteins there. In that application, you actually don’t even solubilize the protein. There’s hardly any water in that bar. It’s really almost a dry protein that has a plasticizer with it, some carbohydrates that actually make that edible. You’re almost eating a dry product. There’s a lot of food chemistry that goes into which product category you’re putting it in. There’s not this straight fast rule that you use whey proteins in this, you use casein and that. It depends on what food chemistry you use and how you put the blend together and then what processing you couple with that to get the characteristic that you’re actually after. Josh White: Can we spend a minute or two talking about the acidified products? They’ve gained a lot of popularity. The market potential is quite large. Can we talk a bit about the [00:17:00] differences between the clear WPIs and our traditional products? Lloyd Metzger: I wanna clarify the question. Are you talking specifically about whey protein only in the clear whey protein beverages versus the normal whey protein beverages? Ted Jacoby III: Yes. Lloyd Metzger: We really start to get into the weeds because we’ve got different whey products. So we’ve got whey protein concentrate. And then that comes in various forms. WPC 34 or WPC 80 are the most common. The 80 and the 34 correspond to how much protein on a dry basis those two products have. And they have whey proteins in the normal ratio that would be in the starting whey. Then we get into a group of products called whey protein isolates. And whey protein isolates go through an additional manufacturing process that allows you to purify the protein further and they’ll have more than 90% protein on a dry basis. And you may start to alter the ratio of the various whey proteins that were present in the starting whey. Now, when [00:18:00] we get into the clear whey protein isolates, we really start to alter the ratio of the proteins that are in there. We’ll also start to change some of the mineral profile of the components that are in that product. And then when we use those isolates in a formulation, we gotta be careful about all the other ingredients ’cause they’re gonna have an impact on whether or not the product is actually clear and whether or not it can be stable to heat. So, you can actually make whey protein stable to heat by controlling the mineral profile and controlling some of the processing conditions. You’re now taking a category of dairy ingredient and you’re starting to use technology IP to be able to provide specific functional characteristics that aren’t normally part of that ingredient. All of these may be called the same thing, and the basic consumer has absolutely no idea what the differences between all these things are. And when they’re looking at a label, they’re probably looking for the word whey protein, and that’s all they’re looking for. Josh White: As we’ve seen the market tighten up, we’ve seen [00:19:00] more inquiries and exploration about the use of pro cream,also called WPPC, also called WPC 70, so many different names. Definitely, in our experience, there’s quite a uniqueness as we originate this product from different manufacturers. Perhaps we can talk a bit more about what this product is and how it differs from the other proteins in the complex. Lloyd Metzger: I talked about WPC 80. That’s just the normal whey protein that we concentrate out of whey. And then, I mentioned whey protein isolate. To convert WPC 80 to a whey protein isolate, you use a filtration step called microfiltration. And in that microfiltration step, you remove any protein that is interacting with fat and take that out of the system. So, if you start with a normal WPC 80 and we’re gonna change it into a WPI. We are gonna go through a microfiltration process and we’re gonna lose about 25% of the protein that was there and all of the fat that was there. And [00:20:00] we’re gonna make a WPI out of that. And that WPI is gonna have about 75% of the protein we started with. The protein that we harvest out of that is actually pro cream. pro cream is just a byproduct of converting WPC 80 into WPI, and it’s gonna have about 25% of the mass of the protein that you started with, and all of the fat that was in that starting WPC 80 material. So that’s why you see it called high-fat WPC 30, and if you dry that down, it’s about a WPC 60. You can take that and blend that with WPC 34. You can do all kinds of things with that ingredient. Manufacturers are always trying to find a home for that. ’cause you’ve got a very high value product that’s easy to market in WPI. Ted Jacoby III: Lloyd, that pro cream, our hunch is there’s a lot more value in that pro cream than the market currently has its head around. Lloyd Metzger: they’re the same proteins that are in WPI, they’re just interacting with a fat. Now the fat [00:21:00] is very unique in that there’s quite a bit of phospholipid fat in there. And so there’s a lot of literature and research being done on the potential health benefits for brain development of phospholipids for infants as well as elderly to help with memory retention and actually help to prevent some Alzheimer’s effects. So, you see some companies starting to market that component that they’ve isolated. I think there is a lot of potential value there. But we’re in the early stages of where that’s gonna go. And you have some companies leading the way that are producing very specialized pro cream type products that are being used in infant nutrition or elderly nutrition. TJ Jacoby: But Lloyd, how do those phospholipids affect the shelf life of pro cream? Lloyd Metzger: They don’t help. The phospholipids are unsaturated fats or partially unsaturated and unsaturated fats are very easy to oxidize, so if they’re not handled properly, you’ll get very stale and oxidized off flavors in the product. It’s something you gotta be careful of. Ted Jacoby III: Oxidized fats, [00:22:00] another way to call that. That’s rancid, right? Yes. Lloyd Metzger: On its way to rancid. Josh White: Another selling point that people will make of the benefits of pro cream are IgGs. Can you guys explain a bit more of what that is to the layman? Lloyd Metzger: So, immunoglobulin is a protein that’s also present in milk. It’s really high in colostrum. It’s at very low levels in milk about 72 hours after the cow was started milking, the levels drop way down, but there is still a low level there. Those immunoglobulins are a very large protein. So when you go through your WPI manufacturing process, they’re gonna partition with that fat and that protein portion that you’re capturing. So they’re gonna go in that pro cream. Looking at the composition of IgG in the different waste streams, you’ll find it’s elevated in that pro cream portion. Now I’d be a little concerned about what kind of shape that IgGs in because you’ve seen a lot of heat [00:23:00] and different manufacturing conditions through that process. So you’d really have to be careful about what kind of claims you’re making based on what kind of shape that IgGs in. Mm-hmm. TJ Jacoby: For an infant, those IgGs will go right into the bloodstream. It’s whole proteins, but for us, it actually has to break up the protein entirely before it can be absorbed into our system. So what kind of functional benefits does IgG bring for an adult? I’d be curious to see what that literature entails. Mike Brown (2): Over the last couple decades, DNA technology has been used more and more to produce valuable proteins, often for medical use like insulin. Are we gonna see a point with the cost benefit of that kind of technology we’ll reach where we can actually use that to produce these whey proteins rather than using a cow? Lloyd Metzger: There’s different levels of concern depending on the particular protein. An individual protein and an individual soluble protein like beta-lactoglobulin and alpha-lactalbumin that are in [00:24:00] whey, those have more potential to be produced in a fermentation type process. ’cause they’re an individual protein. You can over express it, you can get a lot of that produced. But when you get to the complexities of multiple proteins that are in whey, that’s when it really becomes uneconomical to do that from a fermentation standpoint. ’cause you’ve gotta produce all of those individually, try to put ’em together, then purify ’em. What people forget is how efficient the cow is. The cow is essentially a walking fermentation tank that feeds itself, controls its own temperature, cleans itself up. All you’ve gotta do is get the milk out of it. When you look at all the steps that go into the process and what it takes to produce it, it’s really hard to beat the efficiency of a cow. Ted Jacoby III: Lloyd, am I right in assuming that the threat of cellular agriculture to dairy would come in the development of specific protein chains and amino acids, but probably not in terms of the complete [00:25:00] protein profile that is delivered in milk proteins and whey proteins. Lloyd Metzger: Correct. And it would be the very high-end, expensive. So the lactoferrin. It would be your first one or some of the IgG, anything that is at low concentration and very high value. Because even if you did everything perfectly, you’re probably still talking $25 to $30 a pound in the manufacturer and isolation process. Well, we we’re really excited about $11 whey protein isolate. Right? You know, and that’s still half the price. Ted Jacoby III: Makes sense. Lloyd, TJ, this was an absolutely fantastic discussion. This was exactly what I wanted to get out of it. I can tell you I learned quite a bit today and I’m sure our listeners will too. Thank you so much for joining us. We really appreciate it. Lloyd Metzger: No problem. Happy to do it. TJ Jacoby: Truly special to be on today, Dad. I grew up listening to a lot of these podcasts, right? Now we’re here, now we’re on it together with you. So, no, it was truly special.[00:26:00]
Today, I'm thrilled to reconnect with Dr. Rocio Salas-Whalen, a board-certified endocrinologist and obesity medicine specialist with more than 15 years of clinical experience, widely recognized as one of the earliest adopters of GLP-1 therapies in the United States. She is also the author of the upcoming book Weightless: A Comprehensive Guide to the New Era of GLP-1 Medications. In our discussion, we explore the transgenerational impact of obesity as a complex, chronic, and deeply multifactorial condition. We discuss the effects of environmental exposures and trauma, the essential role of education in overcoming weight-loss resistance and managing obesity, and the physiological changes women experience in the perimenopause-to-menopause transition. We explain the importance of body positivity and image, reframing our thoughts around obesity and being overweight, and why building and maintaining muscle is non-negotiable. We dive into the physiology of GLP-1 medications and specific targets for women in perimenopause and menopause, ways to address weight-loss stalls, and the effects of the weight bias so deeply entrenched in our society. Dr. Salas Whalen also shares her thoughts on alternatives and additions to GLP-1 therapies, clarifying the importance of protein and strength training while using GLP-1 drugs. This conversation with Dr. Salas-Whalen is truly invaluable, and I highly recommend her upcoming book, Weightless. IN THIS EPISODE, YOU WILL LEARN: • What people come to understand about “normal eating” after starting GLP-1s • How GLP-1s interrupt the binge–guilt–shame cycle • The role GLP-1s play in helping people stay in control of food rather than letting food control them • Strategies for avoiding side effects when using GLP-1 medications • Why certain foods trigger problems on injection days • Importance of proper guidance to prevent severe side effects • The impact a prescriber's guidance has on your success with GLP-1s • Why treatment plans must be tailored to each patient's needs and metabolism • Factors doctors consider when deciding whether to add additional medications to a GLP-1 plan Connect with Cynthia Thurlow Follow on X, Instagram & LinkedIn Check out Cynthia's website Submit your questions to support@cynthiathurlow.com Join other like-minded women in a supportive, nurturing community (The Midlife Pause/Cynthia Thurlow) Cynthia's Menopause Gut Book is on presale now! Cynthia's Intermittent Fasting Transformation Book The Midlife Pause supplement line Connect with Dr. Rocio Salas-Whalen Website On social media: @drsalaswhalen Dr. Rocio's Book, Weightless - Pre-order now! (Releases 12-30-25)
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Welcome to Ozempic Weightloss Unlocked, where we dive into the latest news on Ozempic, from medical breakthroughs to lifestyle impacts.Ozempic, a glucagon-like peptide one receptor agonist, mimics a hormone that curbs appetite, slows stomach emptying, and boosts insulin, leading to significant weight loss. Studies from the University of Texas at Arlington show it helps people shed up to twenty percent of body weight over months by suppressing hunger.Exciting pill option now available. Reuters reports the Food and Drug Administration approved Novo Nordisk's twenty-five milligram oral semaglutide pill, branded Wegovy, for chronic weight management in adults with obesity or overweight plus related conditions. In trials from Healthbanks, daily semaglutide pills led to nearly fourteen percent body weight loss over sixty-four weeks, versus two percent on placebo. AOL notes oral Wegovy users lost thirteen point six percent over fifteen months, cutting sick days in half.Beyond weight, new benefits emerge. University of Colorado Anschutz research highlights GLP-one agonists like Ozempic easing knee osteoarthritis pain and improving function in obese patients, per a Denmark and Canada trial.American Cancer Society explains most loss happens in year one, slowing after, with some regain upon stopping, so long-term use with diet and exercise is key. Older adults often quit early, per New York Times via American Medical Association, due to muscle loss or shortages, regaining weight.Pair with healthy habits for best results, listeners. Consult your doctor.Thanks for tuning in, listeners. Subscribe for more updates. This has been a Quiet Please production, for more check out quietplease.ai. Some great Deals https://amzn.to/49SJ3QsFor more check out http://www.quietplease.aiThis content was created in partnership and with the help of Artificial Intelligence AI
This week, The Daily is revisiting some of our favorite episodes of the year and checking in on what has happened in the time since.In the past few years, GLP-1 weight-loss drugs like Ozempic and Zepbound have been radically reshaping the people's lives, changing appetites and health.But the drugs also have the power to affect other parts of consumers' lives, including their romantic relationships.Lisa Miller, who writes about health for The New York Times, tells the story of how these drugs upended one couple's marriage.Guest: Lisa Miller, a domestic correspondent for the Well section who writes about personal and cultural approaches to physical and mental health.Background reading: Listen to the original version of the episode here.Weight-loss drugs have lesser-known side effects on relationships.Photo: Katherine Wolkoff for The New York TimesFor more information on today's episode, visit nytimes.com/thedaily. Transcripts of each episode will be made available by the next workday. Subscribe today at nytimes.com/podcasts or on Apple Podcasts and Spotify. You can also subscribe via your favorite podcast app here https://www.nytimes.com/activate-access/audio?source=podcatcher. For more podcasts and narrated articles, download The New York Times app at nytimes.com/app.
This episode is part of The Best of Habits & Hustle, a series where I revisit some of the most impactful conversations we've shared. In this one, I sit down with Dr. Mary Claire Haver to break down what's happening during perimenopause and menopause and why so many women are left confused and guessing. We get into why estrogen matters far beyond hot flashes, how muscle loss and belly fat accelerate in midlife, and why strength training becomes non-negotiable as women age. She cuts through the fear and misinformation around hormone therapy, who it's really for, and why women deserve better conversations with their doctors.She also shares a no-BS take on testosterone for women, GLP-1 medications, and why there are no shortcuts if you want to protect muscle, metabolism, and long-term health. Dr. Mary Claire Haver is a board-certified OB-GYN, Menopause Society Certified Practitioner, #1 New York Times bestselling author of The New Menopause, and founder of The ‘Pause Life. She's become one of the most trusted voices helping women understand what midlife is actually asking of their bodies. What We Discuss: (08:43) The difference between perimenopause and menopause (21:12) Why estrogen matters far beyond hot flashes (23:07) Muscle loss, belly fat, and metabolic changes in midlife (46:06) Why strength training is non-negotiable as women age (27:10) Hormone therapy myths and who it's actually for (25:50) Testosterone for women and when it makes sense (38:27) Pellets, patches, and safer hormone options (52:04) GLP-1 medications and the risk of muscle loss Thank you to our sponsors: Therasage: Head over to therasage.com and use code Be Bold for 15% off Air Doctor: Go to airdoctorpro.com and use promo code HUSTLE40 for up to $300 off and a 3-year warranty on air purifiers. Momentous: Shop this link and use code Jen for 20% off Manna Vitality: Visit mannavitality.com and use code JENNIFER20 for 20% off your order Prolon: Get 30% off sitewide plus a $40 bonus gift when you subscribe to their 5-Day Program! Just visit https://prolonlife.com/JENNIFERCOHEN and use code JENNIFERCOHEN to claim your discount and your bonus gift. Amp fit is the perfect balance of tech and training, designed for people who do it all and still want to feel strong doing it. Check it out at joinamp.com/jen Find more from Jen: Website: www.jennifercohen.com Instagram: @therealjencohen Books: www.jennifercohen.com/books Speaking: www.jennifercohen.com/speaking-engagement Find more from Dr Mary Claire Haver: Website: www.thepauselife.com Instagram: @drmaryclaire Tiktok: @drmaryclaire Youtube: @drmaryclaire Facebook: @drmaryclaire Pinterest: @thepauselife
This episode covers: • Trump Drug Pricing Deals and Access to Longevity Medications New drug-pricing agreements announced under President Donald Trump aim to lower the cost of high-priced prescription drugs through negotiated rebates and pricing pressure on major pharmaceutical companies. Early reporting suggests these changes could affect cardiometabolic and longevity-relevant medications, including GLP-1 diabetes and obesity drugs. Dave explains why the real question is not headline savings, but whether lower prices actually reach patients at the pharmacy counter. He breaks down how affordability shapes real-world access, adherence, and long-term prevention strategies, and why policy decisions can matter more than new mechanisms when it comes to sustainable longevity care. Source: https://longevity.technology/news/trump-sets-new-drug-pricing-deals-with-big-pharma/ • 5:2 Intermittent Fasting Outperforms Daily Dieting on Metabolic Health A controlled study compared three popular strategies in people with obesity and type 2 diabetes: 5:2 intermittent fasting, time-restricted eating, and continuous daily calorie restriction. All approaches improved weight and HbA1c, but the 5:2 protocol produced larger reductions in fasting glucose, triglycerides, and insulin resistance. Dave explains why periodic restriction can outperform constant dieting, how to structure fasting days without tanking performance, and how to pair intermittent fasting with CGM data and training schedules for better metabolic flexibility and long-term health. Source: https://www.sciencedaily.com/releases/2025/07/250715043351.htm Full paper: https://www.nature.com/articles/s41598-025-32673-9 • Cocoa's Theobromine Linked to Slower Epigenetic Aging New research highlighted by Aging-US suggests that theobromine, a bioactive compound found in cocoa, is associated with epigenetic markers of slower biological aging. Dave breaks down what epigenetic aging clocks actually measure, why this finding adds credibility to cocoa's cardiometabolic benefits, and why most chocolate products cancel out the upside with sugar and ultra-processing. He explains how to think about food-derived bioactives without turning them into hype-driven anti-aging shortcuts. Source: https://www.aging-us.com/news-room/theobromine-from-cocoa-linked-to-slower-biological-aging • Organ-Specific Biological Age Clocks Predict Disease Risk More Accurately A large Nature study built biological aging clocks for individual organs using blood-based proteomics, showing that organ-specific aging predicts disease and mortality better than a single “bio age” number. Dave explains why you can be biologically young overall but still have an aging brain, arteries, or kidneys, and how this reframes longevity from generic anti-aging to targeted organ protection. He explores how sleep, blood pressure, glucose control, and exercise map differently to different organs, and why precision aging metrics are the future of prevention. Source: https://www.nature.com/articles/s43587-025-01016-8 • Copper Peptides and the Rise of Skin Longevity Copper peptides like GHK-Cu are moving from niche skincare into serious longevity conversations. Human data show strong effects on collagen synthesis, barrier repair, and wound healing, in some cases outperforming traditional retinoids. Dave explains why skin is not just cosmetic but a key immune and environmental interface, how copper peptides fit into repair-focused protocols, and why cycling repair and stress mirrors smarter approaches to training and recovery across the body. Source: https://www.vogue.com/article/copper-peptides Auro Wellness Copper Peptide with Discount (click on skincare and scroll to Copper Peptide): https://aurowellness.com/pages/dave All source links provided for direct access to the original research and reporting. This episode is designed for biohackers, longevity seekers, and high-performance listeners who want practical strategies grounded in real science and real-world constraints. Dave Asprey translates emerging research, policy shifts, and clinical data into actionable upgrades for metabolism, fasting, biological age tracking, skin health, and long-term prevention. New episodes every Tuesday, Thursday, Friday, and Sunday. Keywords: Trump drug pricing deals, prescription drug affordability, GLP-1 access, cardiometabolic medications, longevity policy, intermittent fasting 5:2, intermittent energy restriction, time restricted eating study, insulin sensitivity improvement, metabolic flexibility fasting, theobromine cocoa aging, epigenetic aging markers, biological age clocks, organ specific aging, proteomics longevity research, brain age dementia risk, vascular aging, copper peptides GHK-Cu, skin longevity protocols, collagen synthesis skincare, evidence-based biohacking news, longevity science updates Thank you to our sponsors! - HeartMath | Go to https://www.heartmath.com/dave to save 15% off. -Generation Lab | Go to http://generationlab.com/, use code Dave20 for $20 off, and see what your body's really doing behind the surface. Resources: • Subscribe to my weekly newsletter: https://substack.daveasprey.com/welcome • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 - Trailer0:19 - Story 1: Trump's Drug Price Deals 2:33 - Story 2: Fasting Reality Check 4:35 - Story 3: Chocolate and Biological Age 6:11 - Substack Update7:30 - Story 4: Organ-Specific Aging 9:05 - Story 5: Copper Peptides for Skin 11:02 - Weekly Wrap-Up See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
In Elby's second episode of the week she talks about her love of rave music, her involvement in End Overdose and she gives us her take on what to do when your kid is struggling with their mental health.To get some GLP-1 action visit ForHers.com/CryingAlso to get free shipping and 365 day returns go to Quince.com/FCOL
Making the case for a better at home A1C test. Orange Biomed is developing a compact, one-drop, at-home A1C testing device they say could make frequent A1C checks easier and more accessible than ever. They're passionate about closing the gap for people who struggle to get to clinics regularly… and the research they share is compelling: four A1C tests a year can lead to a nearly 4% reduction in A1C levels. We'll talk about why more frequent A1C monitoring matters—even in the era of continuous glucose monitoring—how their new device works, and what early clinical trial results look like. This podcast is not intended as medical advice. If you have those kinds of questions, please contact your health care provider. More about Orange BioMed here Announcing Community Commericals! Learn how to get your message on the show here. Learn more about studies and research at Thrivable here Please visit our Sponsors & Partners - they help make the show possible! Learn more about Gvoke Glucagon Gvoke HypoPen® (glucagon injection): Glucagon Injection For Very Low Blood Sugar (gvokeglucagon.com) Omnipod - Simplify Life Learn about Dexcom Check out VIVI Cap to protect your insulin from extreme temperatures The best way to keep up with Stacey and the show is by signing up for our weekly newsletter: Sign up for our newsletter here Here's where to find us: Facebook (Group) Facebook (Page) Instagram Check out Stacey's books! Learn more about everything at our home page www.diabetes-connections.com Episode transcript: Stacey Simms 00:05 Today on diabetes connections, making the case for a better at home A1C test. Orange biomed is developing a compact, one drop device that they say could make frequent A1C checks easier and more accessible. They're sharing research that four A1C tests a year can lead to a nearly 4% reduction in A1C levels, but they say a lot of people can't get to the clinic that much. We'll talk about why this matters, even in the era of CGM, how the device works and what the early clinical trial results look like. This podcast is not intended as medical advice. If you have those kinds of questions, please contact your healthcare provider. Welcome to a bonus episode of diabetes connections. I hope your December is going well and that you know somehow you're able to take some time for yourself in the middle of all the holiday rushing around this time of year can be magical and stressful and exhausting and wonderful, and you know, all the things. And it's the same thing over here, super busy getting all this stuff done before the end of the year. Love it. But, you know, getting podcast episodes out, writing all the things we write and planning for next year, as they say, We're staying booked and busy. But quick behind the scenes here to better explain this episode, I taped this interview way back over the summer during the ADA Scientific Sessions conference. I had some technical problems. I actually thought I lost this interview. There were two interviews that seemed to have gone missing. We're going to air the other one very soon. But thankfully, I do have backups upon backups. So all the info that you're going to hear today is still relevant. This product, a small A1C test, is still in development. The only dated bit is about their follow up event that took place in August. Orange Biomed was launched in 2021 in South Korea, with its US headquarters in Providence, Rhode Island. Its founders are two Duke University alums, and they're my guests, CEO Yeaseul Park and Co-President Unghyeon Ko, We are also joined by Janice Dru-Bennett. She is a senior advisor at the company. Now, English is not the first language of two of these three speakers. This is a good time to remind you that most podcasting platforms have pretty good transcription services these days, especially Apple, I think they have a fantastic real time transcription service for podcasts that has been impressive to me in how they translate diabetes language. They're getting better at it. But I am also going to put a transcript of the interview in the show notes, which I don't normally do because the podcast services have gotten so good at it, but I think it could be helpful for at least a few of you out there. Okay, here is my conversation from the floor of ADA from the team at Orange biomed. Yeaseul Park, Janice Drew Bennett and Dr Ko, Welcome to diabetes connections. I can't say live from ADA, because we're taping this to air later, but you're all there. Thank you so much for joining Yeaseul Park 03:08 me. Yes, thank you. We're 03:10 excited to be here. Oh Stacey Simms 03:11 my goodness. Can I ask first, how is the trip? I mean, yes, let me ask you. You guys came a long way. Yeaseul Park 03:17 Yeah, it was 13 hours from Korea. But it's I'm so excited, because this event is really one of the times, and this is actually our third time attending ADA. Stacey Simms 03:31 That's great. And we have so many questions for you, but Janice, let me ask you, you're there as everybody's setting up at the kind of beginnings of the show. What is it like right now for people who aren't familiar with ADA, Janice Dru-Bennett 03:42 yes, you can hear the hammers in the background, although, but not on this podcast, but there's a lot of noise and people walking by. We're just setting up this the day before the exhibit hall opens and Dr Cole will be presenting at the Innovation Hub tomorrow, which is where we're sitting right now, with tables of innovators will be showcasing their diabetes innovations, and Stacey Simms 04:04 there's a lot to get to. Dr Koh, I know you're presenting, but yes, let me ask you, like, what why? I know you said it's your third year, but why is orange biomed at ADA, what is your goal Yeaseul Park 04:16 for us? ADA, is for a learning experience. As well as a platform to share. We come to see how all those around the world are fighting against diabetes, whether through clinical research, digital tools or technologies or community programs. At the same time, you're so proud to hear what orange biomat is building anytime, and eight months exhausting. That makes diabetes monitoring not accessible, not so many. And this year is especially exciting because Dr ko our co founder of orange buying at the group of speaking at ADA brand new program the innovation Hall. Stacey Simms 04:58 That's awesome. So Dr Koh, tell me. Little bit about this, the Innovation Hub is pretty cool, but what are you going to be talking about? Unghyeon Ko 05:05 Yeah, actually, I'm talking about the engineering part. I mean our technology, so our orange biomed, we are trying to solve a simple but a serious problem about the A1C accessibility. So to increase the A1C accessibility. So we are, we are developing at home device to measure the A1C level. So I'm, I'm talking about how difficult to increase the accessibility of A1C, but our technology is handled that difficult problem. So we now he's so agreed. So I'm going to introduce our technology and emphasize the importance of the A1C measurement at home. Stacey Simms 05:49 Yeah, so A1C, it's interesting. My son was diagnosed at two, and in the pediatric world, you know, they'll just prick a finger generally and have that A1C right away. But my husband lives with type two, and he gets his labs drawn. And then it takes forever. So tell me a little bit before we go further about what you're hoping to do and making this easier for the patient, Speaker 1 06:10 the frequent monitoring of A1C is so important to prevent the diabetic complications. So the money, so if you there is some so I can say that there is a research that if you measure the A 1d the four times a year, the People's A1C level is decreased like 3.8% but if you measure the A 1d at one per year, Then the A1C level is increased 1.5% so the frequent A1C monitoring is so important to prevent the diabetes complications. But problem is A1C measurement is only available at clinical site at this moment, so most of the A1C monitoring is done by the clinical side. So that's why people are difficult to monitoring A1C, because they have to visit the clinics forever. So is so like four times, or even eight times visit the clinics or hospital is quite difficult, especially in the people living in the far area from the hospital. So that's why the home A1C test is required. So I think that's why the accessibility of the A1C is one of the important things in managing the diabetes complications. Stacey Simms 07:39 Dr Koh, is there evidence that, I mean more frequent A1C testing, I think would give many people peace of mind, perhaps. But is there evidence that it really does help in your health? Speaker 1 07:51 Oh, yes, it is actually like from there is the research, like the famous research about the A1C level, like the research name this t and this research proved that the A1C is the one of the strongest predictor of diabetes complication. So A1C is completely related with the risk of diabetes complication. So like keeping A1C on the 7% dramatically lower the risk of diabetes complications. And also, there is another research in UK, the UK PDS study, and that study said they are A1C. Lowering A1C by just 1% can reduce overall mortality by 15% and microvascular complication by 37% so the roaring A1C is the goal of the treatment of the Yeaseul Park 08:47 diabetes. So Stacey Simms 08:48 when I think of at home diabetes tests, blood tests, seem like they're they're really sensitive, right? You have to be very careful with things like that, although we do, we did finger sticks at home for years and years. Are there challenges with at home A1C testing that that people like me could mess up, Yeaseul Park 09:06 sure actually when I was doing pandemic outside system? So it's a new Yeaseul Park 09:19 box of mustard with five or six needles inside, and we need to collect this blood to sound the left result. But then I really tried to collect the requirement matter blood, which is like it was like bleeding. Oh, it's not just retiring in one block, one drop of block, but it's like you need to try, yeah, many times, not just in one spot, to collapse in the block. And the other way you. Built female in, built a lot more broadly, to store your venous blood, and that's features like discomfort. Stacey Simms 10:10 Would you mind taking us through your experience with the A1C testing? You were talking about how much blood it took? Yeah. Yeaseul Park 10:17 So it, it requires many, many drops of blood. So I felt like it's like bleeding, and you make a lot of mess around the table. And so I felt, even though it's it was a topic time it was pandemic. So that's the only option I had at that time, but I wanted to make it simple and easier. And the other types of point of care devices only use a drop of blood still have some limitations, because we all don't want to bleed too much, so sometimes we try to finger stick very small and just squeeze to get enough blood. But if you squeeze to get enough sample volume, that's make your other liquid, like sweats, can also mix with your blood, and that actually affects the accuracy of the testing usually so many point of care devices also not recommend you to squeeze to get enough blood, so that means you need to treat a little too deep to get enough. So we really wanted to make this whole process or simpler and more problem. Stacey Simms 11:43 Can you share a little bit about what the device looks like, what the patient experience is when they use it? Speaker 1 11:48 Dr, CO, so our device is a palm size. Is in most like, like self, self poem, so it's a palm size device. So our device has no switch, but there is only a slider in the front of the device. So if you slide that, you can the device is turned on and you can insert the cartridge, and the cartridge is disposable cartridge. So after that, you just collect your blood and dilute it in the collecting tube and drop the sample into the cartridge, then analyze the A1C like automatically. So it's quite similar with the covid by covid test kit. So the covid test kit collect the sample in your nose and mix with the Rickett and drop it right? And it's quite similar. Stacey Simms 12:45 So do you do a finger stick to put on the cartridge? How much blood to yells? Point, you know? How much blood do you need? Speaker 1 12:52 Our devices for home use device, so it's quite we use a very different technology, because our device analyze the red blood cell one by one. So actually, we don't need exact unlike like five micro or 10 micro, we don't need the exact sample block. So we just need one drop of blood. So if the one drop is big, or if the one drop is right or small, it's fine for us. So one drop of blood, mix with their sample and drop one drop onto the cartridge. So maybe you can, you can drop one more than one drop, but we recommend one drop. So one drop of blood sample my dinner the rest yesterday pointed out that the skeezing the finger of blood is a problem for other device because, because in our body, there is a body wicked inside your under, under your skin. So if the body wicked is mixed with the blood samples, so it might be a problem because it dilute the blood sample. But our device, we analyze the Red Cross itself. So if it is diabetes, I think so we will find so you just puncture very best, and if you scale it, and it's totally fine for us. So it's, it's one of the good point of our device. Yeaseul Park 14:20 How long does it take to get the results? It takes like, five minutes. Okay, yeah, and that's all at home. Yeah. Yezel, who do you see using this? Who is this for? Basically, it's for everyone. I think whoever has pre diabetes, diabetes type one, type two, and especially, I think who has limited access to primary care or lab testings. You know, many people who are older, tends to have more, especially the people who has limited access to primary care or lab testings. We believe this device can give more value to them. Yeah, and especially some people who have limited mobility, if they are older, or if they have experienced that amputation or something like that, they cannot go to the hospital by themselves. They need a caregivers to drive them to the hospital for the simple lab testing. But now I think it empowers patients who has that limitation still can take control their health by using this kind of home use device. How accurate Stacey Simms 15:33 is it? I assume you have studies, and you've done some trials on how on the accuracy? Yeaseul Park 15:37 Dr, CO, do you want to add that? Speaker 1 15:40 Oh, yeah. So we are preparing the clinical trial. So the official clinical trials will be done within this year, but so that's our plan. But we we tested our device already using the in in last year. So last year, feasibility studies show that our device is quite similar with other point of care devices, and hopefully because at that time, our device, our especially our cartridge sensor, we just manufacturing our own like our in our lab. So this time, the official clinical trial in in this year, we are going to manufacturing in the factories so it might be more precise. So we hopefully we trying to chase the hospital accurate. Stacey Simms 16:30 And I have to ask, where more and more people with diabetes are wearing a CGM and looking at time and range. What would you say to people who would tell you, well, we don't really need A1C anymore. We have time and range. Dr Cody, I see you nodding. Go ahead, yeah, yeah. Speaker 1 16:47 So that's a very important point, but because the timing range is also important, and the CGM is very great technology for diabetes people. But problem is, like the A1C and C GM target different, like the CGM target the hypothesemia, but the A1C targeting the diabetes complications. So like, if you measure the timing range and you can manage your average glucose more nicely, but it might be prevent your hypothenia. But if you want to assess your diabetes management, you might be measure A1C. So if you measure timing range, but you also have to measure the A1C. So A1C is for everyone's and so. And also, the point is, if you don't treat the insulin, or if you don't treat the any medications, then you don't need to actually using the CGM, that's the ADH recommendation. So, but in in that case, you need the A1C as well. So A1C for everyone, and the CGM is for the people who treated the insulin. That's the ADA guide, right? And then, Stacey Simms 18:12 yes, let me just ask you. You know, you came all this way. As you say, this is your third time at ADA. Trials are starting soon. What's your hope here? Is this something you see in homes of everyone who has any kind of diabetes? What's the big goal for Orange biomed? Yeaseul Park 18:28 Every time we talk to a day, we can feel what's going on here in diabetes industry. It's a huge maybe first year, I the most frequently hard keyword was aid system. But after that, we now have GLP one, and now we hear more keyword around obesity. So that's a little slightly different trend I can feel. And once you come and join this full sessions, then I can see there's make everyone is making a progress, and we are all together. Want to fight against diabetes in their own way or with their own expertise, whether it's pharmaceutical, whether it's medical device or diabetes, sex, sometimes any other community programs that really support this patient and families, the community, and it's Really this whole atmosphere actually really motivates our team and myself, and we can feel the value. I can really feel this we are doing something valuable to patients and our community, and that's the most great thing, like the greatest thing that I can take when I come back to home with a. After the ADA. And for sure, we want to have opportunity to make voice what we are doing at Orange biomed, and want to deliver this value to the patient and other healthcare professionals. Otherwise, even though we are working hard to make this progress, no one knows, and that makes any changes the world. So that's the important purpose we are coming here. That's great. Stacey Simms 20:30 Janice, before I let you all go, I know you wanted to talk about an event you've got coming up in Chicago. Can you tell me a little Janice Dru-Bennett 20:37 bit about that? Yes, we're really excited for Orange biomed to be hosting the first map your health event, a local event here in Chicago, we have done a solving healthcare challenges webinar to announce our map your health campaign, which is, monitor your A1C, monitor your health and then adapt your treatment and prevent chronic disease. And we're actually going to be hosting on August 16, from 10am to 3pm in Chicago at their humble Park, Health Wellness Center, the first local event, inviting all local partners. We'll have some virtual sessions, showcase with yoga or ask the endocrinologist. So we'll have a very exciting agenda that both virtual and on site participants can join in, eat healthy foods. See, see what's in Chicago from a screenings perspective, and really get people motivated to map your health. So hashtag, map your health. Tell your your your health story, and let's get everyone, um, healthier. Wow. Stacey Simms 21:35 Okay, fantastic. Well, yes, I'll park Dr co Janice, thank you so much for joining me. Have a terrific show. I know this is an audio podcast, but especially behind you. Yassil, it has been wild to watch the construction guys are going by and motorized carts and things are going up behind you. So have a wonderful ADA. Keep us posted, and we'll get the word out about your event in August and going forward. Thanks so much for joining me. more information in the show notes about the studies and about orange biomed. You can sign up for alerts and emails from them as their product moves forward. So if you're interested, definitely check that out. Thank you to my editor, John Bukenis from audio editing solutions, thank you so much for listening. I'm Stacey Simms. I'll see you back here soon. Until then, be kind to yourself. Benny 22:30 Diabetes Connections is a production of Stacey Simms media. All Rights Reserved, all wrongs avenged.
Send a Text Message. Please include your name and email so we can answer you! Please note, this does not subscribe you to our email list, it's just to answer if you have a questions for us. In this year-end episode, I'm sharing the top five lessons that transformed my own health—and the health of so many patients I've worked with. These weren't quick fixes or resolutions that fizzled out in February. These were identity-level shifts that changed how I eat, move, think, and show up for myself.You'll hear about how my tastes evolved (yes, your palate really can change), how movement became a true non-negotiable, why structure creates more freedom—not less—and the mindset practices that kept me anchored during the busiest seasons. I also share the patterns I've seen repeatedly in patients navigating GLP-1 medications, metabolic healing, emotional eating, and long-term weight management.This episode wraps the year with grounded wisdom, compassion, and tools you can start using today.In This Episode, You'll Learn:Why your taste buds genuinely change over time—and how to create the conditions for that shift.The identity shift that makes daily movement automatic (and non-negotiable).How simple routines and structure actually reduce stress, emotional eating, and evening overeating.The mindset training required to maintain weight loss and navigate busy seasons with less friction.The role of community and support in sustaining long-term behavior change.Why building momentum—not perfection—was the biggest theme in both my life and my patients' successes this year.All of the information on this podcast is for general informational purposes only. Please talk to your physician and medical team about what is right for you. No medical advice is being on this podcast. If you live in Indiana or Illinois and want to work with doctor Matthea Rentea, you can find out more on www.RenteaClinic.com Not Sure Where to Start With the Podcast? I've Got You.Get my free Podcast Roadmap—a simple guide to help you find the episodes that matter most to your journey. Whether you're on GLP-1s, navigating plateaus, or just starting out, there's something here for you.Support the show
Estados Unidos ha aprobado la primera pastilla para adelgazar basada en la hormona natural GLP-1, que reduce el apetito. El analista económico Marc Vidal ha analizado en la sección 'Salida de emergencia' de 'Herrera en COPE', con Sergio Barbosa, las profundas implicaciones económicas que este fármaco podría tener en los modelos de consumo.Vidal ha explicado que, según un estudio de la Universidad de Cornell, esta aprobación no es solo un avance médico, sino "el inicio de un cambio estructural en los patrones de consumo". Ha señalado que el precedente inyectable, Ozempic, ya mostró "señales claras de un cambio relevante en los hábitos de consumo", a pesar de su alto precio y su uso original para la diabetes.El estudio revela que los hogares que usan estos tratamientos reducen su gasto en supermercados en un 5,3 % y en restaurantes de comida rápida en un 8 %. Este ajuste se concentra sobre todo en snacks, bebidas azucaradas, alcohol y bollería, lo que anticipa un cambio ...
We got the ball rolling in 2025 with this episode, and it ended up at the very top of the activity list, so we'll close out the year with it as well! Thank you, Dr. Eric Bricker for joining us in the studio for Episode 48 of the Astonishing Healthcare podcast. Known for his entertaining and educational videos covering all sorts of hot topics in and around healthcare and employer/employee benefits, Dr. Bricker and host Justin Venneri discussed the issues of high-cost drugs and access to claims data - two topics he covered on AHealthcareZ - Healthcare Finance Explained - that should [still] be top of mind for plan sponsors as pharmacy costs continue to rise.Dr. Bricker shared several ways employers, depending on their size and risk tolerance, may be able to navigate the challenge of rising pharmaceutical costs for orphan and other expensive drugs - including GLP-1s. He also explains how the RFP process can be used to secure the plan's claim data, which is necessary to meet fiduciary obligations. While every plan is unique, most plan sponsors face similar challenges that the traditional PBM model isn't flexible or aligned enough to solve.Lastly, Dr. Bricker expressed astonishment by the complacency out there, but he was right! The setup was perfect for an acceleration in the pace of change in 2025, and we see the momentum carrying over into 2026 - so, tune in to hear why, if you didn't catch Episode 48 the first time around.AHealthcareZ Reference VideosHigh Cost Orphan Disease Drugs ExplainedDo Employers Own Their Claims Data? It's Complicated.Related ContentAH030 - Plan Sponsors Need a Source of Truth; Get Your Data Now & Find It, with Jeff HoganHow to obtain Rx data and what to do with itAH093 - Health Benefits that Work for Everyone: Aligning Incentives & Focusing on Members' Needs, with Susana Villegas SpillmanWhy Savings Don't Materialize: The Truth About Pharmacy Benefit Procurement eBook (Free)For more information about Capital Rx and this episode, please visit Judi Health - Insights.
#905. What's actually worth your money when it comes to injectables, lasers, and skincare… and what's just hype?Kaitlyn sits down with her trusted injector and go-to skincare expert, Elisabeth Smith, for a no-BS beauty chat that answers the questions everyone is quietly Googling. From Botox myths that refuse to die, to how to actually find a good injector in the age of social media, they break down what works, what doesn't, and what can seriously go wrong if you're not informed. Kaitlyn also walks through a treatment she's doing that day, why it makes sense for her skin, and how to think about timing, safety, and expectations.They get into the treatments people love to hate, what delivers the biggest return on investment, budget skincare that's genuinely worth it, and the beauty advice online that makes professionals cringe. If you've ever wondered where to spend, where to save, or whether you should do anything at all—this episode is your guide.If you're LOVING this podcast, please follow and leave a rating and review below! PLUS, FOLLOW OUR PODCAST INSTAGRAM HERE!Thank you to our Sponsors! Check out these deals!Macy's: If you're still checking off your list, hop online or pop into Macy's, grab those last-minute gifts with same day pick up, where they have something for everyone. Only at Macys.com. Real Real: Get $25 off your first purchase when you go to TheRealReal.com/vineEPISODE HIGHLIGHTS: (8:20) — How to actually find a good injector (and why social media can't be trusted)(21:00) — The “danger zones” of filler that can lead to blindness
The holidays are here, and while they are meant to be a time of joy and connection, they often bring along digital distraction, fear of overeating, and anxiety about the impending New Year.In this short and sweet episode, Andrés Preschel breaks down the three most important themes for navigating the holiday season intentionally. You'll learn how to optimize your physiology to enjoy family meals without the guilt, how to create a digital barrier to ensure you are truly present with your loved ones, and exactly how to execute a "Past Year Review" to set yourself up for massive success in the year ahead.Discover your science, optimize your life, and enjoy your holidays.In This Episode, You'll Learn:1. The Gift of Presence (Digital Detox Strategies)Why you should delete social media for the last week of the year (less than 2% of your life!).How to use "intervention" tools to break the dopamine loop and stop doom-scrolling.Tools mentioned: The One Sec app and Shift technology.2. Preventing Holiday Weight Gain (Without Dieting)How to enjoy potlucks and home-cooked meals without "dieting" or counting calories.The Pre-Meal Protein Primer: Consuming 20-30g of lean protein (Greek yogurt, whey, lean beef) 30–60 minutes before a meal to suppress Ghrelin and boost GLP-1 (satiety).Fiber & Bitters: Why eating handfuls of dark leafy greens (arugula, spinach) before your meal slows gastric emptying and reduces glucose spikes.Food Sequencing: The correct order to eat your food to manage insulin response (Fiber/Protein first, Carbs last).The Postprandial Stroll: How a 10–15 minute walk after dinner pulls glucose into the muscles without insulin.3. The "Past Year Review" (Strategic Planning)Why New Year's Resolutions often fail and what to do instead.A step-by-step guide to Tim Ferriss's Past Year Review exercise.How to use the 80/20 rule (Pareto's Law) to identify the people and activities that bring you peak joy—and how to schedule them immediately.Creating a "Not-To-Do" list to eliminate the negative triggers from your life.
Links:AI in medicine: https://www.england.nhs.uk/long-read/guidance-on-the-use-of-ai-enabled-ambient-scribing-products-in-health-and-care-settings/Various wearables: https://uk.wellnesspulse.com/lp/best-fitness-trackers/?campaignId=23304304009&adgroupId=&adId=&targetId=&device=c&gunique=CjwKCAiAmKnKBhBrEiwAaqAnZ4MBo1x_tOV7RB1FPjSEqiYWae8AyeixJJsGEVTlbapiaEWJL7D8cBoCYs8QAvD_BwE&gad_source=1&gad_campaignid=23300097782&gbraid=0AAAAAqKJRpkXwMKHsYb3EhuFeRzIdPUV2Health Check on BBC World Service: https://www.bbc.co.uk/sounds/play/w3ct6vk0Elinzanetant for menopause: https://www.gov.uk/government/news/mhra-approves-elinzanetant-to-treat-moderate-to-severe-vasomotor-symptoms-hot-flushes-caused-by-menopauseThe new weight loss drugs (GLP-1 agonists): https://my.clevelandclinic.org/health/treatments/13901-glp-1-agonistsExperimental Alzheimer's Drug: https://www.sciencedaily.com/releases/2025/12/251222080119.htmSave your life in slow motion and those of others by subscribing now and sharing. Thank you for listening and for your support. It means a lot to me. Hosted on Acast. See acast.com/privacy for more information.
Sarah shares her LADA journey—misdiagnosed as type 2, overwhelmed postpartum, then empowered by a new endocrinologist and GLP-1 therapy—showing how persistence and better care can change diabetes management. Free Juicebox Community (non Facebook) Type 1 Diabetes Pro Tips - THE PODCAST Eversense CGM Medtronic Diabetes Tandem Mobi ** twiist AID System Drink AG1.com/Juicebox Use code JUICEBOX to save 40% at Cozy Earth CONTOUR NextGen smart meter and CONTOUR DIABETES app Dexcom G7 Go tubeless with Omnipod 5 or Omnipod DASH * Get your supplies from US MED or call 888-721-1514 Touched By Type 1 Take the T1DExchange survey Apple Podcasts> Subscribe to the podcast today! *The Pod has an IP28 rating for up to 25 feet for 60 minutes. The Omnipod 5 Controller is not waterproof. ** t:slim X2 or Tandem Mobi w/ Control-IQ+ technology (7.9 or newer). RX ONLY. Indicated for patients with type 1 diabetes, 2 years and older. BOXED WARNING:Control-IQ+ technology should not be used by people under age 2, or who use less than 5 units of insulin/day, or who weigh less than 20 lbs. Safety info: tandemdiabetes.com/safetyinfo Disclaimer - Nothing you hear on the Juicebox Podcast or read on Arden's Day is intended as medical advice. You should always consult a physician before making changes to your health plan. 01:37 Tandem Mobi: [https://tandemdiabetes.com/juicebox] 01:57 Eversense 365: https://eversensecgm.com/juicebox 02:13 GLP-1 and Mounjaro Strategies: [https://podcasts.apple.com/us/podcast/juicebox-podcast-type-1-diabetes/id962416631?i=1000656313813] 06:40 The Juicebox Toolbox: [https://bit.ly/jbplists]
Go to https://www.Ro.co/SLOAN to see if your insurance covers GLP-1s - for free. *Go to https://www.ro.co/safety for boxed warning and full safety information about GLP-1 medications. Let's get into it! We get get into #timotheechalamet #kyliejenner #kendalljenner #ryanrenolds #joekeery #britneyspears and much more.. Learn more about your ad choices. Visit megaphone.fm/adchoices
What if you could quantify the five biggest drivers of chronic illness, then fix the right one first? That's the promise of MVX Plus, a simple, low‑cost blood test that scores malnutrition, toxicity, inflammation, infection, and mitochondrial dysfunction—then turns the results into a clear plan. We sit down with Dr. Darren Schmidt to unpack why so many people spin their wheels on diets and prescriptions, and how a focus on cellular function changes the outcome.We start by challenging the food pyramid mindset and the shaky ground of observational nutrition studies. Instead of worshiping food groups, we get practical about macronutrients. Protein rises as the quiet hero of satiety and metabolic stability, while ultra‑processed foods are engineered to keep you hungry. From there, we dig into real‑world cases: when a patient with lingering gut issues needed steak, not another antimicrobial; when a high MVX score traced back to an acute sinus infection; and how removing toxin exposures can drop your 5‑year risk score in weeks.The takeaway is a blueprint, not a fad. Personalize protein intake, repair digestion so you can actually use it, identify and remove toxic hits, and support mitochondria—sometimes with targeted tools like benfotiamine (B1) to restore energy. We also compare GLP‑1 drugs to low‑carb physiology and explain when each makes sense. If you're tired of guessing, the MVX framework gives you a compass: run the test, act on the dominant bottleneck, and watch your score head down as your health climbs.Want the data to guide your next move? Order the MVX test at the nhca.com (upper right: MVX test), and if you want hand‑holding, become a patient and track your progress every 6–8 weeks. If this conversation helped, follow, share with a friend who's stuck, and leave a review so more people can find their way back to real health.Join the What if it Did Work movement on FacebookGet the Book!www.omarmedrano.comwww.calendly.com/omarmedrano/15min
On this hard-hitting episode of Start Today, I bring back Jay Campbell to expose what's really happening behind the scenes with peptides, GLP-1 drugs, and Big Pharma's quiet push to shut down affordable optimization. We break down why January could change everything—from access restrictions to rising costs—and what men need to know now before the window closes. We also get into why Ozempic is already obsolete, what's coming next with GLP-3s, how peptides actually work, and the three non-negotiables for men who want strength, clarity, and longevity. No hype. No shortcuts. Just real talk you won't hear from your doctor.
This episode originally dropped on: June 2, 2025When some of the biggest names in menopause medicine want to learn to lift heavy, they turn to this week's guest, Nike Master Trainer and midlife fitness advocate Holly Rilinger, founder of the LIFTED Method. Because Holly gets it. She's been through her own journey with damaging diet culture, body image issues, and a challenging perimenopause that has left her navigating sheet soaking night sweats, brain fog, and fatigue. Through a midlife-specific training plan and tailored hormone therapy regimen (including testosterone), she's been able to reclaim her energy and power and is devoted to helping others do the same. This week we dive into the science and strategy behind Holly's Lifted Method and her Blueprint programs designed specifically for women in midlife, as well as for those using GLP-1 medications. This conversation is packed with insight, honesty, and a lot of muscle. You can learn more about Holly and her programs at www.theliftedmethodcoaching.comHolly Rilinger is a Nike Master Trainer, author, and founder of the LIFTED Method: An in-person and virtual platform with the focus of empowering people at all levels to strength train. Holly is dedicated to delivering innovative, science-backed training methods in an environment that prioritizes growth, resilience, and a lifelong passion for fitness. Holly coaches in her East Hampton studio and on her virtual platform. She is also the founder of LIFTED Blueprint, formerly Menopause Bootcamp, a program designed specifically to help women in midlife get stronger, feel more energized, and gain confidence as they navigate this powerful phase of life. She is also the creator of LIFTED's newest program for SLP-1 patients–GLP-1 Blueprint in partnership with Dr. Alexandra Sowa of So Well.Sign up for our FREE Feisty 40+ newsletter: https://feisty.co/feisty-40/Learn More and Register for our 2026 Tucson Bike Camp: https://feisty.co/events/gravel-camp-x-bike-mechanic-school/Join the Feisty Strong Barbell Club: https://feisty.co/strong-club/ and use code: STRONG2026 to save $50 Follow Us on Instagram:Feisty Menopause: @feistymenopause Hit Play Not Pause Facebook Group: https://www.facebook.com/groups/807943973376099 Support our Partners:Previnex: Get 15% off your first order with code HITPLAY at https://www.previnex.com/ Midi Health: You Deserve to Feel Great. Book your virtual visit today at https://www.joinmidi.com/Wahoo KICKR RUN: Use the code FEISTY to get a free Headwind Smart Fan (value $300) with the purchase of a Wahoo KICKR RUN at https://shorturl.at/maTzL
In this episode of the Smarter Not Harder Podcast, Cynthia Thurlow joins Dr. Scott Sherr for a wide-ranging and refreshingly honest conversation about fasting, female hormones, GLP-1s, and navigating midlife as a high-performing woman. With clarity and nuance, Cynthia breaks down what works — and what backfires — when it comes to metabolic health for women over 35. Join us as we delve into: • Why intermittent fasting isn't a one-size-fits-all solution • How hormone shifts change the fasting game for women • What GLP-1s like Ozempic and Wegovy really do — and don't do • How to stay metabolically flexible through perimenopause This episode is for you if: • You're a woman over 35 trying to fast smarter, not harder • You're curious about GLP-1s but want balanced, science-based insight • You've hit a metabolic wall and need smarter strategies • You want practical, hormone-informed tools for fat loss and focus You can also find this episode on… YouTube: https://youtu.be/5oVPHVbyUcw Find more from Cynthia Thurlow: Website: https://www.cynthiathurlow.com Instagram: https://www.instagram.com/cynthia_thurlow_ Find more from Smarter Not Harder: Website: https://troscriptions.com/blogs/podcast?utm_source=youtube&utm_medium=video&utm_campaign=snh_podcast_guest_episode_2025_10&utm_content=podcast_asset Instagram: https://www.instagram.com/troscriptions Get 10% Off your purchase of Clinical Metabolomics Module by using PODCAST10 at https://www.homehope.org Get 10% Off your Troscriptions purchase by using POD10 at https://www.troscriptions.com Get daily content from the hosts of Smarter Not Harder by following @troscriptions on Instagram.
This week we dive deep into the world of GLP-1 medications—what they are, how they work, and why they're transforming approaches to weight loss and metabolic health. Dr. Nanos shares both professional expertise and personal experience, discussing the science behind these medications. You'll learn who these treatments are for, their benefits and side effects, evolving accessibility, and the importance of safe, medically guided use. The conversation also spotlights the broader impact on mental well-being, with advice about advocating for your health and prioritizing your wellness. If you've wanted to learn more about GLP-1s, this episode is for you. Be sure to share it with a friend. Subscribe: https://www.youtube.com/@herstarringrole Follow + Listen, + Review: APPLE PODCASTS Follow + Listen, + Review: SPOTIFY PODCASTS Join Michele's Newsletter + Get a List of 52-Selfcare Tips GUEST INFORMATION Website: https://www.kindhealthgroup.com/ Heart Health Interview with Dr. Nanos IG: https://www.instagram.com/drgeorginenanos/ If you enjoyed this interview, please take a moment to rate and review it on Apple Podcasts or other podcast player. *The Good Life with Michele Lamoureux podcast and content provided by Michele Lamoureux is for educational and entertainment purposes only. It does NOT constitute medical, mental health, professional, personal, or any kind of advice or serve as a substitute for such advice. The use of information on this podcast or materials linked from this podcast or website is at the user's own risk. Always consult a qualified healthcare or trusted provider for any decisions regarding your health and wellbeing. This episode may contain affiliate links.
What actually makes a brand break through and stay relevant long after the hype fades? I wanted to explore that question with someone who sees behind the scenes of real growth, not just what looks good online. In this episode, I sit down with Emily Hickey to talk about what performance marketing really means, why specificity matters more than volume, and how the smartest brands focus on what is already working instead of chasing every new idea. We get into product positioning, influencer strategy, why hero products matter, and how marketing decisions connect directly to identity and behavior. We also talk about fitness, discipline, GLP-1 medications, and why building a business often forces you to build yourself at the same time. Emily Hickey is the co-founder and CEO of Chief Detective, a performance marketing agency working with leading consumer brands across Meta, Google, and social platforms. She also advises companies like Goop and Weight Watchers, helping leadership teams think clearly about growth, positioning, and longevity. What We Discuss: (00:00) Why Most Brands Stall Even With Great Marketing (07:18) What It Actually Means To Be A Top Meta Agency (14:42) Why Product Strategy Matters More Than Ads (22:05) The Biggest Mistake Early Brands Make Online (30:11) How Influencer Marketing Really Drives Sales (38:47) Why Winners Win And How To Spot Them Early (47:26) How Fitness Builds Confidence Beyond The Gym (56:02) The Real Link Between Personal Growth And Business Success Thank you to our sponsors: Prolon: Get 30% off sitewide plus a $40 bonus gift when you subscribe to their 5-Day Program! Just visit https://prolonlife.com/JENNIFERCOHEN and use code JENNIFERCOHEN to claim your discount and your bonus gift. Therasage: Head over to therasage.com and use code Be Bold for 15% off Air Doctor: Go to airdoctorpro.com and use promo code HUSTLE40 for up to $300 off and a 3-year warranty on air purifiers. Magic Mind: Head over to www.magicmind.com/jen and use code Jen at checkout. Momentous: Shop this link and use code Jen for 20% off Manna Vitality: Visit mannavitality.com and use code JENNIFER20 for 20% off your order Amp fit is the perfect balance of tech and training, designed for people who do it all and still want to feel strong doing it. Check it out at joinamp.com/jen Find more from Jen: Website: www.jennifercohen.com Instagram: @therealjencohen Books: www.jennifercohen.com/books Speaking: www.jennifercohen.com/speaking-engagement Find more from Emily Hickey: Website: www.chiefdetective.com Instagram: @emilyhickey_official YouTube: Emily Hickey: Growth Series
Elby Taylor guests with us this week and on this episode we talk all about working on tour and why being in a sorority wasn't right for her but might be right for you. Hey, it's never too late! To get some GLP-1 action visit ForHers.com/CryingAlso to get free shipping and 365 day returns go to Quince.com/FCOL
In this episode of Beast Over Burden, hosts Niki Sims and Andrew Jackson unpack how GLP-1 medications, TRT, and peptides are changing the coaching landscape—and what that means for strength training. Drawing from years of hands-on coaching experience, Andrew explains how GLP-1s and strength training interact, why muscle preservation becomes critical during rapid fat loss, and how tools like TRT can accelerate progress without changing the core rules of adaptation. If you're a lifter training on GLP-1 medications, considering TRT, or a coach working with clients using these tools, this episode delivers a first-principles framework for protecting muscle, managing recovery, and training for long-term health. Competing at 40 looks different than it did in your 20s—and that's not a bad thing. In this episode of Beast Over Burden, Niki Sims and Andrew Jackson recap Niki's recent deadlift-only meet, breaking down why she decided to compete again, how she trained while traveling, what went wrong during the taper, and what the experience revealed about strength, perspective, and showing up at 40. This isn't a PR story. It's an honest look at preparation, adversity, meet-day chaos, and the value of competing without tying your identity to a number on the bar. What You'll Learn in This Episode Why a deadlift-only meet made sense at 40 How pulling 405 in training reopened the door to competing The training structure that stayed simple—and the one key change that mattered How frequent travel and inconsistent gyms affected recovery and performance What a "rough taper" actually feels like A realistic approach to weight management without extreme cutting Meet-day logistics, warm-up chaos, and disrupted attempts Why missing a lift doesn't mean missing the point What it means to be proud of your strength at 40 Timestamps 00:00 – Intro and why this meet recap matters 02:33 – Pulling 405 and deciding to compete again 06:49 – Training approach and key program changes 10:47 – Training while traveling: 20 gyms in one year 15:08 – Getting sick, a rough taper, and reset expectations 20:35 – Weight management and attempt selection 28:24 – Meet-day chaos, warm-ups, and attempts 36:45 – What Niki learned from a deadlift meet at 40change 46:00 – Final thoughts: tools don't replace training 48:10 – How to work with a Barbell Logic coach PS - Ready to finally see real change? Lean In 12 delivers noticeable fat loss, improved strength, and unmatched consistency through expert coaching and daily support — all in one premium 12-week program. Now discounted for a limited-time. Start your transformation: https://bit.ly/4rKpkLr Connect with the hosts Niki on Instagram Andrew on Instagram Connect with the show Barbell Logic on Instagram Podcast Webpage Barbell Logic on Facebook Or email podcast@barbell-logic.com
What if your diagnosis is not a life sentence, but an invitation to rebuild your health, identity, and purpose from the ground up? Josh Trent welcomes Dr. Ryan Lazarus, Functional Medicine Practitioner, to the Wellness + Wisdom Podcast, episode 788, to reveal how surviving a near death experience without a pancreas shattered medical labels, reshaped his beliefs about healing, and led him to a holistic blueprint that integrates mindset, food as medicine, trauma stored in DNA, mental fitness, connection, and purpose as the true foundations of lifelong health.
GLP-1 weight-loss drug injections have slimmed many waistlines and wallets. U.S. regulators have now approved a much less expensive alternative; Novo Nordisk has gotten the green light for an oral version of Wegovy. Pills are cheaper to manufacture than injectables, and that could be a game-changer. Then, consumers still feel pessimistic heading into the new year, and more Americans are staying unemployed for longer.
GLP-1 weight-loss drug injections have slimmed many waistlines and wallets. U.S. regulators have now approved a much less expensive alternative; Novo Nordisk has gotten the green light for an oral version of Wegovy. Pills are cheaper to manufacture than injectables, and that could be a game-changer. Then, consumers still feel pessimistic heading into the new year, and more Americans are staying unemployed for longer.
Plus: The U.S. bans new China-made drones from DJI and Autel Robotics, sparking outrage among pilots. And U.S. regulators approve the first GLP-1 weight-loss pill, a tablet formulation of Novo Nordisk's Ozempic and Wegovy. Daniel Bach hosts. Sign up for WSJ's free What's News newsletter. Learn more about your ad choices. Visit megaphone.fm/adchoices
Mazel Morons! Today, we're diving into the messy science of metabolism- does it actually slow down with age, or are we just… fat? The guys debate fast vs. slow metabolisms, Michael Phelps' 12,000-calorie diet, childhood food trauma, GLP-1s, fasting culture, and how much the brain really burns thinking (spoiler: not enough to earn a Snickers). Plus: the greatest candy of all time, the danger of gas-station Kratom, menstrual face masks (???), gay sheep couture, and relationship & parenting advice from Moron Mail. What more could you ask for? Love ya!Leave us a voicemail here!Follow us on Instagram and TikTok! Sponsors:Quo - Quo is offering my listeners 20% off your first 6 months at Quo.com/goodguysShopify - Whether you're just wanting to test an idea out, or you're getting serious about launching your own brand - it's never been easier to get started on shopify.com/goodguys.Ollie - Go to ollie.com/goodguys and use code goodguys to get 60% off your first box!Home Chef - HomeChef.com/GOODGUYS for FIFTY PERCENT OFF your first box and free dessert for life!Please note that this episode may contain paid endorsements and advertisements for products and services. Individuals on the show may have a direct or indirect financial interest in products or services referred to in this episode.Produced by Dear Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Legendary Life | Transform Your Body, Upgrade Your Health & Live Your Best Life
What if you could lose 20 or even 30 pounds—and still be marching straight toward diabetes, fatty liver disease, or early heart disease? In Part 1 of this New Year Series, Ted reframed the entire conversation around aging by explaining why longevity isn't about living longer, but about extending healthspan—the years you remain strong, mobile, mentally sharp, and independent. >>> Click here for part 1 In Part, he tackles one of the most dangerous misconceptions in modern health: the belief that weight loss automatically equals health. In an era of GLP-1 medications, more people are losing weight than ever—but metabolic disease continues to rise. Ted explains why this disconnect exists and why weight loss is only the lowest bar of health, not the finish line. He also breaks down what metabolic health actually means and explains the critical role of muscle, cardiovascular fitness, blood sugar control, and lifestyle habits in determining how you feel today and how you'll age tomorrow. If you've ever assumed that losing weight was enough, this discussion will challenge that belief—and show you what needs to come next. You'll learn: Why weight loss alone does not guarantee metabolic health How obesity rates can fall while diabetes and fatty liver disease rise What metabolic health really means—and why only a small percentage of adults have it Where GLP-1 medications fit—and where they fall short Why healthspan—not lifespan—should be the real goal after 40 What Ted discusses in this episode: (00:00) Introduction (02:19) The Reality of Metabolic Health (03:51) Understanding Metabolic Health and Its Importance (16:16) The Role of GLP-1 Medications (21:05) The Importance of Muscle and Preventing Muscle Loss (23:19) Weight Regain and Long-Term Health (25:48) Conclusion: Building Real Health Beyond Weight Loss