Podcasts about Cleveland Clinic

We all know how important mental health is but unless you are VERY lucky, you're on your own.  There are the rare programs out there for pediatric endocrinology and we've got one of the best Dr. Taylor Stephens is a pediatric psychologist with the Cleveland Clinic who specializes in pediatric endocrinology conditions. She's here to share what we can all do, right after diagnosis, and years later to support our kids and ourselves, if you're a caregiver or an adult living with type 1 This podcast is not intended as medical advice. If you have those kinds of questions, please contact your health care provider. Learn more about the Mental Health + Diabetes Conference here. Use promo code "dmhconnections" to save 15% off your ticket Announcing Community Commericals! Learn how to get your message on the show here. Learn more about studies and research at Thrivable here Please visit our Sponsors & Partners - they help make the show possible! Omnipod - Simplify Life All about Dexcom  All about VIVI Cap to protect your insulin from extreme temperatures The best way to keep up with Stacey and the show is by signing up for our weekly newsletter: Sign up for our newsletter here Here's where to find us: Facebook (Group) Facebook (Page) Instagram Check out Stacey's books! Learn more about everything at our home page www.diabetes-connections.com 

Linda Hill: Genius at Scale Linda Hill is the Wallace Brett Donham Professor of Business Administration and Faculty Chair of the Leadership Initiative at Harvard Business School. Globally recognized as a top leadership and innovation expert, Linda has been named by Thinkers50 as one of the world's top five management thinkers. She is the co-author, along with Emily Tedards and Jason Wild, of Genius at Scale: How Great Leaders Drive Innovation (Amazon, Bookshop)* We all want to think of ourselves as innovative, but it's often not easy to know exactly what that means in practice. In this conversation, Linda and I explore what her research shows that leaders do to drive innovation successfully – and how each of us can get just a bit better. Key Points Rather than coming up with a vision and asking people to follow it, innovation is about creating the culture and capabilities to create the future together. Innovation leadership shows up in three ways within organizations: the Architects, the Bridge Builders, and the Catalysts. Instead of setting the stage for themselves, innovative leaders set the stage for others. Often, we view horizontal relationships through the lens of organizational politics. The most effective innovation leaders view these relationships as leadership opportunities. Traditional team structures are a starting point, but not an ending point. Leaders at Mastercard, Pfizer, and Cleveland Clinic all brought in team members from both inside and outside the organization. Rather than thinking about a decision as final, it's helpful for innovation leaders to frame it as a “working hypothesis.” Resources Mentioned Genius at Scale: How Great Leaders Drive Innovation by Linda Hill, Emily Tedards, and Jason Wild (Amazon, Bookshop)* Interview Notes Download my interview notes in PDF format (free membership required). Related Episodes How to Build an Invincible Company, with Alex Osterwalder (episode 470) The Way Innovators Get Traction, with Tendayi Viki (episode 512) Doing Better Than Zero-Sum Thinking, with Renée Mauborgne (episode 641) Discover More Activate your free membership for full access to the entire library of interviews since 2011, searchable by topic. To accelerate your learning, uncover more inside Coaching for Leaders Plus.

Keller Cliffton is the co-founder and CEO of Zipline, the world's largest commercial autonomous delivery system, which today serves 5,000 hospitals across multiple countries and saves an estimated 17,000 lives per year. In this episode, Keller breaks down his extreme hiring philosophy that has powered Zipline for over a decade. He also walks through Zipline's full origin story: from a near-dead home robot startup to a scrappy bet on drone blood delivery in Rwanda, to 135 million autonomous miles flown. In today's episode, we discuss: Why Zipline hires teenagers over PhDs Why the best startup employees are "heat-seeking missiles for pain" The 5 leadership attributes Zipline has never shared publicly The brutal firing advice that shaped Keller's leadership How Rwanda's health minister changed Zipline's trajectory References: Airbnb: https://www.airbnb.com Alfred Lin: https://www.linkedin.com/in/linalfred/ Amazon: https://www.amazon.com Apple: https://www.apple.com Brian Chesky: https://www.linkedin.com/in/brianchesky/ Cleveland Clinic: https://my.clevelandclinic.org Netflix: https://www.netflix.com Paul Kagame: https://www.linkedin.com/in/paulkagame/ Reflect Orbital: https://www.reflectorbital.com Sequoia Capital: https://www.sequoiacapital.com SpaceX: https://www.spacex.com Sphero: https://www.sphero.com Tesla: https://www.tesla.com University of Washington: https://www.washington.edu Walmart: https://www.walmart.com Zipline: https://www.zipline.com Where to find Keller: LinkedIn: https://www.linkedin.com/in/kellerrc/ Twitter/X: https://x.com/Keller Where to find Brett: LinkedIn: https://www.linkedin.com/in/brett-berson-9986094/ Twitter/X: https://twitter.com/brettberson Where to find First Round Capital: Website: https://firstround.com/ First Round Review: https://review.firstround.com/ Twitter/X: https://twitter.com/firstround YouTube: https://www.youtube.com/@FirstRoundCapital This podcast on all platforms: https://review.firstround.com/podcast Timestamps: 00:00 Introduction 02:11 Why Zipline doesn't hire for experience 06:04 Are founders born or made? 07:37 Why Zipline hires 17-year-olds over PhDs 17:03 The employees Zipline doesn't want 18:53 The ultimate startup hire is a "heat-seeking missile" 20:36 Why blind references are a non-negotiable 23:07 Can candidates admit when they screwed up? 30:10 Zipline's secret leadership playbook 35:16 Why you should always fire quickly 36:26 The early vision for Zipline 39:48 How Zipline almost died - twice 44:55 From toy robots to drone delivery: Zipline's pivot 51:35 How Rwanda's health minister changed everything 57:10 Why Zipline's launch was a "complete disaster" 1:04:05 Scaling from 1 hospital to 5000 1:05:17 The 10x hardware cost rule every founder should know

In clinical practice effective nutrition, exercise, and obesity care is rarely about identifying the single "best" plan on paper. Instead, sustainable change depends on behavioral psychology: understanding the person's context, motivation, barriers, and patterns, then co-designing practical steps that can actually be implemented in real life. David Creel PhD, RD is a clinical psychologist and registered dietitian working in weight management at the Cleveland Clinic. Dr. Creel discusses how clinicians can bridge the gap between "optimal recommendations" and what is most likely to create actual behaviour change. This includes a combination of using collaborative communication, self-monitoring, skill-building, relapse prevention planning, and a multidisciplinary framework. Behavioral and psychological factors shape food choices, physical activity, and adherence far more than knowing the newest guideline. In addition, the modern obesity treatment landscape (including GLP-1 receptor agonists) increases the need for structured behavior-change support: people may experience new hope and new fear (especially fear of weight regain), and the key clinical question becomes how to use these tools to build durable habits and reduce relapse risk over the long term. Timestamps [03:09] Start of interview [05:31] Challenges in nutrition and exercise recommendations [11:01] Behavior change in real-world practice [16:32] Self-monitoring and its importance [23:48] Non-scale victories and positive body image [25:58] Focusing on body capabilities over aesthetics [27:20] Integrating activity into lifestyle [30:30] Exercise snacking and practical tips [33:36] Impact of GLP-1 receptor agonists [38:24] Addressing fear of weight regain [41:24] Effective multidisciplinary obesity treatment Related Resources Go to episode page Join the Sigma email newsletter for free Subscribe to Sigma Nutrition Premium Enroll in the next cohort of our Applied Nutrition Literacy course LinkedIn: Dr. David Creel Danny Lennon X/Twitter: @drdavidcreel @NutritionDanny

Dr. Timothy Gilligan and Dr. Calvin Chou discuss the updated guideline on patient-clinician communication in oncology. They highlight clinical recommendations and strategies on topics such as communication skills and practices that apply at every visit, principles for telehealth interactions, cross-disciplinary communication, facilitating involvement of the patient's support network, discussing prognosis, goals of care, treatment selection – including clinical trials, end-of-life discussions, overcoming barriers to communication, facilitating discussions of cost of care and financial toxicity, mitigating stigma, and setting boundaries with patients. Dr. Gilligan and Dr. Chou also share how clinicians can enhance their communication skills through skills practice opportunities and experiential learning. They discuss how fundamental communication is to optimal patient care and look to the future on how generative AI may impact healthcare communication. Read the full guideline, "Patient-Clinician Communication: ASCO Guideline Update"  TRANSCRIPT This guideline, clinical tools and resources are available at www.asco.org/supportive-care-guidelines. Read the full text of the guideline and review authors' disclosures of potential conflicts of interest in the Journal of Clinical Oncology,  https://ascopubs.org/doi/10.1200/JCO-26-00118       Brittany Harvey: Hello and welcome to the ASCO Guidelines podcast, one of ASCO's podcasts delivering timely information to keep you up to date on the latest changes, challenges, and advances in oncology. You can find all the shows, including this one, at asco.org/podcasts. My name is Brittany Harvey, and today I am interviewing Dr. Timothy Gilligan from Taussig Cancer Institute and the Center for Excellence in Healthcare Communication at Cleveland Clinic, and Dr. Calvin Chou from the University of California and Veterans Affairs Health Care System in San Francisco, co-chairs on "Patient-Clinician Communication: ASCO Guideline Update." Thank you for being here today, Dr. Gilligan and Dr. Chou. Dr. Timothy Gilligan: Thank you for having us. Dr. Calvin Chou: Delighted to be here. Brittany Harvey: And then just before we discuss this guideline, I would like to note that ASCO takes great care in the development of its guidelines and ensuring that the ASCO Conflict of Interest Policy is followed for each guideline. The disclosures of potential conflicts of interest for the guideline panel, including Dr. Gilligan and Dr. Chou who have joined us here today, are available online with the publication of the guideline in the Journal of Clinical Oncology, which is linked in the show notes. So then I would like to dive into what we are here really today to talk about. So Dr. Gilligan, this guideline updates the patient-clinician communication guideline that was first published in 2017. What prompted this update and what is the scope of this updated guideline? Dr. Timothy Gilligan: So I think with the first guideline, that was the first draft of it that we published five or six, seven years ago, really we were focused on getting the content right, what was the state of the knowledge at that time, and I was very happy with what came out of that. But when I looked back on it, I thought there were ways we could make it more accessible and more practical. Because what we really would like would be for people to apply what we know and then communicate more effectively with patients and colleagues. And one of the reasons I was really excited on the membership of the panel we had this time was I thought they were very well selected to help us do that, is to really think about what are practical guidelines, practical steps we can tell people to take that will improve their own experience and the experience of patients and the quality of care. Brittany Harvey: Absolutely, thinking about operationalizing that guideline really improves the dissemination and the uptake of these recommendations. So then, Dr. Chou, I would like to review the key recommendations and strategies across the clinical questions that the guideline addressed. I realize today with our limited time we may not be able to go through every recommendation and strategy, so we will start with some of the highlights. First, let's address the highlights of the process of communication with patients and their support networks. This includes the questions that address what communication skills and practices apply at every visit across the continuum of care, principles for telehealth interactions, cross-disciplinary communication, and facilitating involvement of the patient's support network. In your view, what are the most important recommendations across these clinical questions? Dr. Calvin Chou: I think the thing that all clinicians know in their bones that they want to be able to do effectively with patients is to communicate information clearly, as well as to communicate in a way that really deepens the relationship, demonstrates empathy, and also demonstrates understanding bilaterally between the various parties. So the communication guidelines that we established in this group, they are fundamental to communication in all conversations throughout healthcare. And the first guideline talks about how clinicians and their team can communicate effectively with the patient and the patient's support network. And those include things like preparing ahead of time; getting a list of the topics that are important to the patient support network so that we can consider them in the visit; making certain that we are hearing what the patients' and the patients' support networks are saying very, very closely; responding to those empathically; and being able to have conversations about care throughout the visit that demonstrate respect and deepen the trust; and then finally, to have some kind of bidirectional understanding, usually through teach-back, that allow both sides to know that communication has occurred as opposed to just been downloaded. The guidelines also talk about applying these same communication skills throughout telehealth communication - that is both in terms of synchronous communication, audio or video, as well as asynchronous communication, i.e., through secure messaging. We also talk about how we can use these same communication skills to communicate effectively with members of our own team. Interprofessional communication is an important part of all the work that we do, and how we can use these very, very same skills in communication with colleagues, with nursing staff, with social workers, and other allied health professionals. These are all very, very important, crucial members of our healthcare team in the delivery of care to our patients. And that is something that we really need to emphasize throughout to try to bring the best of communication in every conversation that we have. Dr. Timothy Gilligan: I totally agree with that. Those are really important points. When I was looking over it in preparation for this podcast, it struck me that we have a lot of recommendations and a lot of small things that we can do either well or not well. And it reminded me of a quotation from a famous chef, Marco Pierre White, who said that perfection is a lot of little things done well. This guideline has a lot of little things that if you do them well, you get better outcomes. And I think the chef's point was that if you want a really delicious dish, you have to pay attention to all those little details. And I think if people go through the guidelines carefully and apply the skills that are along the lines of what Dr. Chou was talking about, we get better results. And those results are really important results. It is not only patient satisfaction, which is really important, but it is also quality of care and outcomes for patients. It is better medical care. It is a better day for us, we have a better day if we have better conversations. Poor communication creates endless headaches for everybody. What I see in the guidelines is it is a lot of little best practices and it requires discipline to learn those. The good news is none of them I don't think are all that hard. The bad news is doing it consistently well every day requires discipline and practice. And what I would hope for these guidelines is that people will read them carefully and think about what they can do to apply what we know more consistently. And I think the interprofessional communication piece, that was something we added this year, is really critical. Medicine has a bad history of really disrespectful behavior. It was almost normalized that different specialties would make fun of each other, that different professions would talk disrespectfully of each other. And we know now that uncivil behavior results in more healthcare errors. And it is not only bad for our teams and our culture, but it is bad for our patients if we are not communicating well with each other. So I thought it was really critical that we added that piece to the update. Brittany Harvey: Absolutely. Those fundamental principles that Dr. Chou outlined are really key across every healthcare interaction, including those interdisciplinary interactions. And as you alluded to, Dr. Gilligan, I think it will really serve clinicians well to review the details and go through every table to read the recommendations and each individual strategy to help them improve their communication in day-to-day interactions. Moving to some of those day-to-day clinical communication scenarios, Dr. Gilligan, I'd like to think through some of those key points. So what is recommended for discussion of prognosis, goals of care, treatment selection, including discussion of clinical trials, and end-of-life discussions? Dr. Timothy Gilligan: So my perspective is that there is a broad theme of flattening the hierarchy that runs through these recommendations and this part of the guideline - that the sections that Dr. Chou just talked about really have a lot to do with the details. What does good communication look like? What are best practices that we can adopt? And I think these other sections are a little bit more, they also have a lot of specific guidelines, but there is a philosophical point that we do better when we talk to the patient at their own level. And we sometimes fail to do that. I remember from about 10 years ago I was in a room with a patient and one of the other doctors said to the patient, "We're going to bronch you tomorrow." And I was trying to think, like, what do they think the patient hears when we use language like that? Like they don't understand what the word means. We are just expecting them to step up to our level. We are not accommodating them, and I think that really interferes with our ability to form effective relationships with patients and communicate clearly. So if we are going to talk about prognosis, goals of care, treatment selection, clinical trials, end of life, the first step for me is that we have to get down to the patient's level, which means listening. We have to ask them what they know, we have to get their perspective. We have to understand what their health literacy level is so that we can have a conversation that takes into account the patient's perspective. And we need to be humble and remember that the patient often has information that we do not have yet unless we ask them and listen to what they say. That is going to change what we think is the best plan of care. And so shared decision-making is really a critical piece of that. One of my favorite trainers who I follow online says, "I make suggestions, you make decisions." And I like to bring that attitude into the room when I talk to patients. It is their life, it is their body, it is their health, it is their decision. It is not my decision. I don't get to tell them what to do. I want to make sure that they make a decision that is based on the best available evidence, but also a decision that is based on who they are and what their values are. And we try to give pointers to how we can have these conversations in a way that is really fully respectful of the patient's autonomy and the importance of the patient's expertise in their own body, their own lived experience. Because there is a risk that we come in with our white coat and we overpower them with our authority, our medical authority, our medical knowledge, and no one likes to be overpowered. And I think we all have a better day if we go in and have a conversation as human beings with each other. Dr. Calvin Chou: I want to underscore this point of having the patient and their support network make the ultimate decisions. Reviewing the evidence from more general literature, it is clear that across demographics that only 10% of patients want us to make decisions for them. 90% of patients want to have at least some say, if not full say, in the decisions that they make, and this is true across age, across gender, educational status, socioeconomic status, veteran status. This is a very, very important point. I think oftentimes we go in thinking we know what's going to happen and we need to make them do that. Thinking about this as a conversation as opposed to a download is an important point. Dr. Timothy Gilligan: And one thing that I think that the guidelines are relevant for here, which is I think one way to achieve honoring the patient autonomy, is to really make a commitment to having a good process, to not be committed to an outcome. So that when we start the conversation, we're not going to say it's a good conversation based on whether it ends up where I wanted it to end up. It's a good conversation based on whether we have a good process, a fair process. And the steps of good communication that are outlined in this guideline help us to establish a good process. And I think if we have a good process, we can trust it will take us to the appropriate outcome, which may be different than the outcome we thought was going to be the appropriate outcome when we started the conversation. Brittany Harvey: Definitely. I think, as you mentioned, tailoring discussions to each individual patient and situation is really critical. And I think in every other podcast episode across guidelines we've really emphasized the importance of shared decision-making. And so talking through the process of it in this guideline will really have impacts across all of ASCO's guidelines. Moving on to the next section of the guideline, this guideline also addresses barriers in the communication process. So Dr. Gilligan, what highlights are there for overcoming barriers to communication, facilitating discussions of cost of care and financial toxicity, mitigating stigma, and setting boundaries with patients? Dr. Timothy Gilligan: Yeah, it's interesting. I want to hear Dr. Chou's perspective on this too. I thought that the communication skills are really important for these conversations, but less powerful or less effective, potentially. For instance, barriers to communication, the big one that comes to mind is language differences. If the patient and the clinician do not share the same language, that results in less good care unfortunately. It results in less good communication. Having skilled translators or interpreters there is essential, and using them with skill is essential, but it does not get us to equality. I mean the best thing for a patient is to have a clinician who speaks their language. Unfortunately, that's not possible. So the second best thing we can do is to have good interpreters or translators to help us work. And then for us to use those people effectively, because oftentimes we cut corners when working with interpreters and shortchange the patient. So it is important to do the best we can. I think it is also important to acknowledge that it's a challenge and no matter how good your communication skills are, it's not going to be the same conversation if you're talking through another person versus directly to the patient. Similarly, with financial toxicity, it is important to talk about it. We need to be open about it. We need to talk to patients about it, but financial stress from healthcare is a real problem, and however well you communicate it, it doesn't make that problem go away. You know, in oncology, our drugs are obscenely expensive, and I can't communicate my way to lower prices. So I can talk about it and legitimize it and empathize, but I feel like I have more power in the other sections to really change the outcome by communicating well than I do with these. But it is important to talk about it. Patients are hugely affected by the cost of care and we need to talk about it with them. I do think for mitigating stigma and setting boundaries, then our communication skills become more powerful. We see everyone in the healthcare system, and when working with individuals who have been subject to stigma because of aspects of their identity, we can help lessen their vulnerability and fear by proactively letting them know that we will strive to avoid perpetuating that stigma, that we will treat them with respect and address them as they wish to be addressed, that we will care for them as dignified and valued human beings. That is not always their experience in the system, but we can choose to be different. We can choose to do better. And our communication skills are important because listening and curiosity are super important in that space. Because if we are talking to people who may be different from us, we need to learn about them by listening and being open and being curious, and replacing, if we have any tendency towards judgment, to replace judgment with curiosity. With setting boundaries, I think it is also really important. I don't think you can show up and be fully present with patients the way I want to, the way we want other people to, if we don't know that there are boundaries. And we know this in other aspects of our care, right? I go into the room and I do intimate physical exams and I ask about intimate aspects of the patient's life. And I'm allowed to do that because there is a non-negotiable barrier to any kind of sexual or romantic contact between me and my patients. We know there's a hard wall there that we don't cross that line, so that when I am doing an intimate exam, we know where that stops and that we're not going to cross boundaries there. But the same thing applies verbally, and I think doctors sometimes and other healthcare professionals sometimes feel like they need to accommodate the patient no matter what. I was hoping the guidelines would send a strong message that, you know, we don't need to put up with disrespectful behavior. That when you go into the room, as a clinician or as a patient, you should be treated with respect. You should feel safe, you should feel like you belong, and if patients are behaving in a way that violates that, then clinicians have a right to speak up and to set limits and to set boundaries. And if we know those boundaries are there, then I think we can lean in closer. If we don't know those boundaries are there, then we kind of have to hold back to protect ourselves. And just to give one of like a million examples you can give, I don't know a woman in healthcare who hasn't had a patient say something sexually inappropriate to them at some point. And that's not okay. I want my colleagues to know that's not okay, and it's okay to set boundaries and they don't have to put up with that. And my hope is that if we know where the boundaries are, then we can step in closer. That's my perspective on these, but Calvin, please, I'd love to hear your thoughts. Dr. Calvin Chou: I want to double-click on everything that you said, Tim. It is so important that we recognize what we have control over and what we don't have control over. And what we don't have control over, for example, language discordance or financial woes of a patient, I have no possible way of controlling that. And so the best I can do in those situations is to sit with them, empathize, and do what I can, whatever power I might have in advocacy or I often refer folks to a social worker that I work very, very closely with, because I have no agency over any of that. At the same time, when we talk about mitigating stigma in healthcare encounters, we have full control over the biases that we have. We may not be aware of them, but we do have control over them ultimately. And so it is up to us really to examine our practices, to see where we have maybe been steered in the wrong direction, where we double down on internal implicit biases that we have carried for our entire lives. And that requires that we approach all of our encounters with everybody in healthcare, with humility, and with an extra eye toward understanding how we are coming across to them, and whether or not at least some of those interactions are infused with bias that we can decrease. And then finally, with the idea of boundaries, there are boundaries in two directions, as Tim was saying a moment ago, that there are boundaries that we must place in between ourselves and patients during examinations and also during interactions. And there's also boundaries that we have to set up that require that we uphold the standards ethically of clinical medicine. And that is, there are certain things- I would never ask a patient out, for example, on a date. And that's an important proscription; that's an important boundary that we must set up between ourselves and patients. Those are clear barriers that we must not breach. There are some barriers that are a little bit less clear. For example, there are some instances where physicians are asking patients who have means to perhaps contribute to a foundation or contribute to the university or to make a large donation to an institution. In some instances, that's a much less clear boundary. For myself, I feel uncomfortable making those kinds of requests, and there are other instances where those requests are actually not just okay to do, but the patient is willing to do those kinds of things. So I think we need to consider that these boundaries are not always set in stone. Sometimes the boundaries move, sometimes the boundaries are different. Brittany Harvey: Absolutely. I think this latest question covered a lot of ground, and I think some key points here are that treating everyone with dignity is really paramount to this guideline. Recognizing the challenges even when they're not solvable is really important, such as thinking about financial issues or perhaps not speaking the same language as a patient. And then building trust and mutual respect between patients and clinicians to establish clear boundaries is really important as well. So, I want to thank you both for reviewing at a high level the recommendations and the strategies from this guideline, and I encourage listeners to review the full guideline and tables for all of the recommendations and strategies to implement these clinical recommendations. So, Dr. Chou, this guideline panel also addressed one education question. So, what are the recommendations for effective ways for clinicians to enhance their communication skills? Dr. Calvin Chou: Thanks for asking, Brittany. When we talk about all of these communication skills, Dr. Gilligan and I have talked for a long time about all these individual communication skills. These are not skills that are necessarily naturally formed within us and that we just roll out without any practice. And that's why we both feel, if I can speak for you, Tim, that we both feel that communication skills training, and high-quality communication skills training, is deeply important. This is training that is less about I'm listening to this podcast and therefore I can communicate better, it's more about skills practice opportunities, experiential learning, oftentimes using that horrifying word 'roleplay' that people don't like to think about roleplay before they're in it, but then once they've done those skills exercises they realize how important it is to actually have practiced some of these skills so that when you get into the real situation, you have an approach to it as opposed to trying to just improvise or make it up on the fly. The other aspect of communication skills training that is deeply important is not just forming the words and speaking to somebody else, it also needs to incorporate practitioner self-awareness and situational awareness that allows us to understand what's going on within us emotionally and attitudinally so that we are interacting moment by moment with patients and their support networks in a way that's authentic, that brings the appropriate amount of vulnerability and expertise to deepen trust between all of those relationships. And finally, when we talk about communication skills training, there are ways to do this kind of training that, I've used ChatGPT, for example, when I'm having some difficulty wondering how to navigate a particular situation, sometimes you can use ChatGPT to give you some suggestions on how to approach that interaction. But at the same time, the most important thing is to be able to have really meaningful practice with other people, with other human beings. Because as much as I might interact with a computer, that computer is not a human being. And what we are talking about is interpersonal communication with emphasis on 'person'. And us as human beings, we understand, in a way that ChatGPT probably will never fully understand, the nuances of the emotional reactions and the importance of human connection between people when we talk to each other. And so therefore, if we can't depend on computers to do this communication skills training, we need institutions to emphasize and invest in all of our continuing ability to communicate effectively with everybody in healthcare. This is probably one of the most important outcomes of this guideline, is not just that communication skills are important, and not just that communication skills training is important, it's that we need everybody to invest in everybody's ability to communicate with each other on the highest possible level that we can bring. Brittany Harvey: Yes, I think it's really important that the panel addressed this question, to emphasize that it's not just individual clinicians, but institutions that really need to value communication and this training to make sure that clinicians are being the most effective communicators that they can be. So, I'd like to move on to the next question, and Dr. Gilligan, ask, in your view, what is the importance of this guideline and how will it impact both clinicians and people with cancer? Dr. Timothy Gilligan: So I would build off of what Dr. Chou was just talking about, which is what we're hoping is that it will serve as a resource that will give people interested in communicating better guidance on where to go, what to do, what are the best practices, what do we know at this time. if you want to get better, what are the methods that are going to help you get better. And ideally I hope it will inspire people to want to get better. Communicating is such a fundamental part of our day-to-day work in healthcare that it needs to be something that we're very, very good at. And as professionals we should aspire to be as good as possible. A lot of this stuff is pretty basic, but we forget to do it. When I had young kids and was teaching them to ski, one of the ski instructors said to me once that there were Olympic skiers who trained at the same mountain where my kids were learning. And he said they would go down easy slopes and just practice basic techniques still. They were good enough to ski in the Olympics going at crazy speeds, but they kept going back to their fundamentals. And my son is a serious soccer player and they do role plays in soccer. They practice drills. They have scenarios they know are going to come up and they artificially recreate that scenario and they practice it over and over again. There's a famous line from a college football coach that you don't practice it until you get it right, you practice it until you can't get it wrong. And I think if people would bring that sense of professionalism to communication, it's a lifelong journey. I'm still trying to get better. It requires practice, it requires discipline. There's a lot that we know, but it doesn't happen without practice. And as Dr. Chou was saying, it's a motor skill. You don't learn it by reading about it. You don't learn it by listening to us talk about it. You learn it by practicing it. And I practice with patients. Not in the sense that I'm doing an experiment, but I work on my skills with patients. And I see how it goes. And when things don't go well, I think of what I could have done differently. And when things do go well, I think of what did I do that helped it go well that I need to make sure I do again next time. And I think I'd love to see people adopt an attitude that they want to be fantastic communicators and they want to get better. And I think the guidelines provide a lot of clues and steps to take for all of us to get better. Dr. Calvin Chou: I heard Tim, you talk about communication being a procedure and that we would never think about going into a room and sticking a central line into a patient without having practiced that over and over and over again to get it right. Not to get it right, to never get it wrong, like you were just saying. And so if we think about communication as the most common procedure in healthcare, then it behooves us all to do the best we can with it. It is a frame shift because we are communicating with each other all the time, oftentimes without thinking. And what we're advocating right now is for everyone to really bring it in terms of communication skills in all settings, because the effect of ineffective communication is not necessarily just making people feel bad. As Tim said at the top of the program, it also impinges on quality of care. It's not just the right thing to do, it's the safe thing to do. Brittany Harvey: Absolutely. And highlighting the fundamentals here and practicing them as clinicians will improve each healthcare interaction. So then, finally, to wrap us up, Dr. Chou, earlier you mentioned ChatGPT and thinking about maybe some technological advances and how those will impact in the future. What are the outstanding questions and priorities for future research for optimal patient-clinician communication? Dr. Calvin Chou: I think there's a lot we still need to learn about in this very, very nascent time of interacting with generative artificial intelligence. We won't know what things are going to be like probably even tomorrow given the vast advances that AI is allowing us to do. And also, as I was mentioning earlier, what AI can never do is to bring the human element into these interactions. And I think that's part of what, maybe that's a lot of what brings people to healthcare, is if they're in need and they have some physical issue that we need to help them solve, it's not just a physical issue, it also is a deep emotional experience. And we have heard many times now cautionary tales of when AI has led people astray to then, for example, allow them to die by suicide. And that is the last thing that we can allow to happen in healthcare. That is the ultimate low-quality item. We need to make certain that everybody is cared for with high quality and high safety. And we're definitely not there yet with AI. We hope that at some point we'll be able to work with AI in order to bring even better healthcare than we have right now, and I think that has been demonstrated to be possible. That is one major outstanding question that we're all going to have to wrestle with. Brittany Harvey: I think that's absolutely a key point. With generative AI quickly evolving, there need to be guardrails in place. And like any intervention, thinking about how to maximize the benefits of it and reduce the harms to make sure that you're preserving that human interaction and communicating effectively, and that patients can receive their health information in an appropriate way. So I want to thank you both so much for your work to update this guideline, to draft all of these recommendations and the strategies, and work with the entire panel to create this excellent product. So thank you for all that work and thank you for your time today, Dr. Chou and Dr. Gilligan. Dr. Timothy Gilligan: Thank you. Dr. Calvin Chou: Thank you, Brittany, so much. Brittany Harvey: And finally, thank you to all of our listeners for tuning in to the ASCO Guidelines podcast. To read the full guideline, go to www.asco.org/supportive-care-guidelines. You can also find many of our guidelines and interactive resources in the free ASCO Guidelines app available in the Apple App Store or the Google Play Store. If you have enjoyed what you have heard today, please rate and review the podcast and be sure to subscribe so you never miss an episode. The purpose of this podcast is to educate and to inform. This is not a substitute for professional medical care and is not intended for use in the diagnosis or treatment of individual conditions. Guests on this podcast express their own opinions, experience, and conclusions. Guest statements on the podcast do not express the opinions of ASCO. The mention of any product, service, organization, activity, or therapy should not be construed as an ASCO endorsement.

The following article of the Tech industry is: “Patient Experience: From Cleveland Clinic to Mexican Hospitals” by David Potes, Director of Sales and Business Development & Costumer Success, TCA Software Solutions. (AA1002)

Can a clinician really thrive in the high-stakes world of pharmaceutical sales?In this episode of Medical Sales U, I sit down with Randy Rhodes, a former Nurse Practitioner at the Cleveland Clinic who successfully transitioned into Oncology Sales. Randy pulls back the curtain on why he left the bedside, the "identity crisis" clinicians face when moving to sales, and the exact strategy he used to land a role at a top pharma company.Whether you are a nurse practitioner, RN, or pharmacist looking to break into the industry, this deep dive provides the tactical roadmap you need to bridge the gap between clinical expertise and commercial success.WHAT YOU'LL LEARN IN THIS EPISODE:* The "Business of Nursing": Why Randy's business degree and clinical background became his "unfair advantage."* The MSL vs. Sales Debate: Why Randy pivoted from the Medical Science Liaison path to the commercial side.* The 4:54 AM Mindset: How a disciplined routine (and CrossFit!) fuels a successful sales territory.* Overcoming the "Salesperson" Stigma: How to stay patient-centric while hitting your quota.* Interview Secrets: The specific questions Randy wasn't prepared for and how you can avoid his mistakes. TIMESTAMPS:0:00 - Intro: Meet Randy Rhodes, NP turned Oncology Pro02:15 - The Louisiana Connection: From Business to Nursing05:30 - Life at the Cleveland Clinic: Bone Marrow Transplant Expertise09:45 - Making the Jump: Why Pharma?13:10 - The MSL Interview Nightmare: Learning the Hard Way18:40 - Reframing "Sales": It's About the Patient22:15 - Landing the Job: The 4-Round Interview Process26:30 - A Day in the Life: Sunday Planning & Territory Hustle32:00 - Staying Motivated When Doctors Say "No"38:45 - Leadership & Advice for Aspiring Reps42:10 - The Power of Feedback: Why Every "No" is a "Not Yet"

Willy sat down once again with Dr. Michael Roizen, bestselling author and Chief Wellness Officer Emeritus at Cleveland Clinic, to explore the science behind living longer, healthier lives. Drawing on decades of research, Dr. Roizen shared practical strategies you can use today, from the benefits of saunas and cold plunges to managing stress, optimizing diet and alcohol intake, improving sleep, and understanding the emerging science behind supplements, peptides, plasma therapy, and exercise. Learn more about your ad choices. Visit megaphone.fm/adchoices

In this episode, Sierra Garvin, Senior Associate Director of Above Brand Marketing at Boehringer Ingelheim speaks with Mandy Leonard, Senior Director of Drug Use Policy and Formulary Management at Cleveland Clinic about the key drivers of rising healthcare costs, including chronic disease, multiple comorbidities, rare diseases, and wasteful spending. They explore practical strategies to lower total cost of care while maintaining quality and improving patient outcomes.This episode is sponsored by Boehringer Ingelheim.

Send a textSpeaking of Women's Health Podcast host Holly Thacker, MD sat down with Cleveland Clinic internist and executive health physician Richard Cartabuke, MD to map out how a single, coordinated visit can compress a month of care—advanced labs, imaging and expert consults—into a focused plan you can actually use. From there, they go deeper: why direct genetic testing beats ancestry kits for medical decisions, how proteomics and multiomics translate your biology into priorities and where whole genome sequencing is headed as targeted therapies arrive.Data is only useful if it drives daily choices, in the interview learn how to turn complex readouts into simple steps: strength training, protein-forward meals, sleep regularity, blood pressure control and stress habits that lower cortisol. On the therapeutic front, they explore GLP‑1 and GIP agonists beyond weight loss—microdosing schedules, inflammation reduction and organ benefits—plus practical ways to access legitimate medication through manufacturer programs and avoid risky compounding. They wrap up the interview with a clear takeaway: start earlier than you think, build a baseline you can track and use precision tools to focus effort where it matters most.Support the show

A native of Albany, New York, Dr. Alex Ford is one of the few clinicians in the country who is both a Board-Certified Family Physician and a Registered Dietitian. After serving as Chief Resident at the Cleveland Clinic, he returned home to revolutionize how we think about 'food as medicine.'He is the co-founder of Neotrition Brands, the Director of Medical Education for 4th Family Inc., and the recipient of the prestigious 2025 CDPHP Top Doctors Peabody Award for his exceptional commitment to patient care. Whether he's mentoring local athletes or helping patients reverse chronic disease through lifestyle intervention, Dr. Ford is at the forefront of the proactive health movement.Sponsors:Bombas offers a wide variety of sock lengths, colors, and patterns that have you covered whether you're working out, going out, or lounging at home. If you want to upgrade your sock game to one that's more comfortable, durable, fashionable, and charitable, head over to⁠ ⁠Bombas⁠⁠ to browse their full collection of everyday wear and don't forget to use code CDSF20 for 20% off your first order.ANCORE: Named the best portable cable machine by Men's Health Home Gym Awards. Head over to⁠ ⁠ancoretraining.com/cdsf10⁠⁠ and use promo code CDSF10 for $50 off your order today.By combining the most potent organic nootropics found in nature, Drink Alchemy delivers sustainable boosts to creativity, memory, energy, & focus in one epic beverage. Enjoy the benefits of real ingredients, natural nootropics, and live with your Mind Unbound by going to⁠ ⁠drinkalchemy.co⁠⁠ and use code CDSF at checkout for 10% off your order today.Thorne vitamins and supplements are made without compromise: quality ingredients ensure your body optimally absorbs and digests your daily supplements, while in-house and third-party testing ensure you're getting exactly what you paid for. Thorne's selection of high-quality supplements can help improve your quality of life. Switch to Thorne's high-quality and extensively tested supplements today at⁠ ⁠⁠⁠thorne.com/u/CDSF⁠⁠.Marc Pro. Marc Pro is an electric muscle stimulator that focuses on improving recovery through its patented technology. Unlike a traditional TENS unit, the Marc Pro doesn't just mask your pain, it improves circulation, flushes lymphatic waste, reduces soreness and fatigue, and prevents overuse injuries – leading to improved performance in the gym and on the field. Start taking your recovery to the next level. Head over to⁠ Marc Pro⁠ and use code CDSF for 10% off your Marc Pro, Marc Pro Plus, or Boost Pro Massage gun.Intro/outro music:⁠ ⁠⁠⁠freebeats.io/⁠⁠ (prod. White Hot)

Hot flashes, night sweats, insomnia, mood swings, brain fog — those are just a few of the things a woman might experience in and around menopause. These symptoms can be uncomfortable, confusing and disruptive. While menopause affects half of the population that reaches middle age, there are still a lot of myths and misconceptions about the condition. Host Charity Nebbe speaks with Dr. Linda Bradley of the Cleveland Clinic in Cleveland, Ohio about the specific challenges facing women of color as they navigate perimenopause and menopause. Then, Dr. Holly Marie Bolger of the University of Iowa will address some menopause myths and bring us up to date on treatment options.

In today's episode, we sat down with Megan Kruse, MD; and Sophia O'Brien, MD. Dr Kruse is a breast medical oncologist at Cleveland Clinic in Ohio. Dr O'Brien is an assistant professor of clinical radiology in the Divisions of Nuclear Medicine and Breast Imaging, as well as the associate program director of the Diagnostic Radiology Residency, at Penn Medicine in Philadelphia, Pennsylvania.In our exclusive interview, Drs Kruse and O'Brien highlighted the various roles of imaging modalities in breast cancer diagnosis and treatment decision-making, noting the unique role of 18F-fluoroestradiol (FES)–PET/CT in lobular breast cancer, how future evolutions of breast imaging may influence FES-PET/CT use, and the importance of strong collaborations between medical oncologists and nuclear medicine physicians.

Dr. Roger McFillin argues that Western allopathic medicine and psychiatry have medicalized normal human suffering by reducing emotions to biological or chemical reactions, turning symptom checklists into fixed identities, and sustaining a drug-driven "sick care" system that creates lifelong customers. He contrasts this with viewing emotions as powerful energy meant to be moved into creation and transformation, cites psychoneuroimmunology, and warns that suppressing fear and distress with pharmaceuticals can worsen long-term outcomes. The conversation covers exposure-based approaches to unlearn fear, the role of media, social media, and advertising in provoking fear and keeping people in an unconscious "drift" state, and the importance of intentional stillness, solitude (distinct from loneliness), prayer or silent meditation, and reducing phone use—especially at the start of the day—to become more conscious and intentional.    McFillin discusses how diagnostic labels like depression and anxiety shape identity, limit choices, and contribute to chronicity and polypharmacy. He contrasts PTSD with post-traumatic growth, emphasizing processing trauma memories, facing avoided situations, challenging overgeneralized threat beliefs, and practicing forgiveness and self-compassion while also taking ownership where appropriate. They also discuss the perceived harms of the "toxic masculinity" concept, men's wellbeing, the loss of wise elders, and how men often bond and cope through shared activities. Dr. Roger McFillin is a clinical psychologist and trauma recovery expert who challenges the medicalization of normal human emotions. With a focus on emotional resilience and personal growth, he specializes in exposure therapy and psychoneuroimmunology, exploring the connection between mind, emotions, and immune health. Dr. McFillin advocates for self-regulation and transforming emotional energy into healing, critiquing the overuse of pharmaceuticals in modern mental health treatment. Through his Substack, Radically Genuine, and podcast, Dr. McFillin educates individuals on overcoming fear, achieving stillness, and reconnecting with their true selves. His work empowers people to shift from a victim mindset to one of active growth, using trauma as a catalyst for resilience and positive change.   Science & Medicine   Psychoneuroimmunology   Overview & science (NIH): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130991/   Exposure Therapy   Wikipedia overview: https://en.wikipedia.org/wiki/Exposure_therapy   Cleveland Clinic explanation: https://my.clevelandclinic.org/health/treatments/25067-exposure-therapy   Anxiety & OCD exposure-based approaches (IOCDF): https://iocdf.org/about-ocd/treatment/erp/   Heart Coherence   HeartMath Institute overview: https://www.heartmath.org/heart-coherence/   Psychiatric Diagnosis & DSM   Critique of DSM and diagnostic categories: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4195174/   Psychiatric diagnosis controversies: https://www.apa.org/monitor/2013/04/diagnosis   Psychology & Healing   Post-Traumatic Growth vs. PTSD   Scientific overview of post-traumatic growth: https://www.apa.org/monitor/2014/01/psychological-recovery   Journal article on PTG vs PTSD: https://www.sciencedirect.com/science/article/abs/pii/S0272735814000412   Forgiveness and Healing   Psychology Today on forgiveness: https://www.psychologytoday.com/us/basics/forgiveness   Research evidence on forgiveness and wellbeing: https://journals.sagepub.com/doi/10.1177/1745691614568356   Self‑Healing Practices   Grounding / Earthing   What is grounding/earthing? https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4378297/   PEMF (Pulsed Electromagnetic Field) Therapy   Basics of PEMF therapy: https://www.health.harvard.edu/pain/pulsed-electromagnetic-field-therapy   Meditation & Stillness   Mindfulness & stillness research: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422583/   Psychology Today on solitude and healing: https://www.psychologytoday.com/us/blog/hide-and-seek/201209/finding-solitude-its-benefits-and-challenges   Cultural & Media Influence   Mind Control & Fear Provocation   The psychology of fear in media messaging: https://www.frontiersin.org/articles/10.3389/fpsyg.2020.566245/full   Media influence and persuasion research: https://www.communicationtheory.org/agenda-setting-theory/   Toxic Masculinity   Research overview on toxic masculinity: https://www.apa.org/advocacy/health-men/guidelines   What toxic masculinity means: https://www.psychologytoday.com/us/blog/the-masculine-mind/201802/what-toxic-masculinity   Dr. Roger McFillin Content   Substack (Radically Genuine): https://drmcmillan.substack.com   Show Notes 00:00 Emotions as Energy 00:33 Medicalizing Suffering 02:44 Exposure Beats Suppression 05:18 Fear and Mind Control 10:21 Stillness vs Loneliness 14:47 Simple Stillness Practices 20:12 Morning Intention Rituals 25:56 Labels and Identity Traps 31:26 Systemic Treatment Harm 32:53 Depression Label Identity 35:08 Sadness Versus Pathology 36:10 PTSD And Growth 38:24 Processing Trauma Fully 41:44 Practical Recovery Steps 45:48 Forgiveness And Ownership 50:37 Toxic Masculinity Debate 56:12 Men Friendship And Elders 01:01:05 Closing Plugs Farewell 38:24 How PTSD Develops 41:44 Practical Trauma Recovery 45:48 Forgiveness and Ownership 50:37 Toxic Masculinity Debate 56:12 Male Friendship and Elders 01:01:05 Closing and Where to Follow   The Hart2Heart podcast is hosted by family physician Dr. Michael Hart, who is dedicated to cutting through the noise and uncovering the most effective strategies for optimizing health, longevity, and peak performance. This podcast dives deep into evidence-based approaches to hormone balance, peptides, sleep optimization, nutrition, psychedelics, supplements, exercise protocols, leveraging sunlight, and de-prescribing pharmaceuticals — using medications only when absolutely necessary. Beyond health science, we explore the intersection of public health and politics, exposing how policy decisions shape our health landscape and what actionable steps people can take to reclaim control over their well-being. Guests range from out-of-the-box thinking physicians such as Dr. Casey Means (author of "Good Energy") and Dr. Roger Sehult (Medcram lectures) to public health experts such as Dr. Jay Bhattacharya (Director of the National Institutes of Health (NIH) and Dr. Marty Mckary  (Commissioner of the Food and Drug Administration (FDA) and high-profile names such as  Zuby and Mark Sisson (Primal Blueprint and Primal Kitchen). If you're ready to take control of your health and performance, this podcast is for you.We cut through the jargon and deliver practical, no-BS advice that you can implement in your daily life, empowering you to make positive changes for your well-being.   Connect with Dr. Mike Hart Instagram: @drmikehart Twitter: @drmikehart Facebook: @drmikehart

This week, we are so excited to share the first of our Career Development Series episodes, developed in partnership with The American Society of Hematology , The ASH Trainee Council, and Hematopoiesis! For years, our listeners have reached out to our show asking for guidance to help navigate their careers. We are so excited to be partnering with an amazing organization like ASH to help make this happen!This time, we welcome two amazing guests, Dr. Hetty Carraway, Director of the Leukemia Program and the Vice Chair of Strategy and Enterprise Development at the Taussig Cancer Institute at The Cleveland Clinic, and Dr. Alfred Lee, Chief of Classical Hematology at Yale School of Medicine, for our inaugural episode where we discuss the importance of mentorship and ask them all the questions most of us have always wondered but are too afraid to ask our mentors. A MUST listen for all trainees!** This episode is created in partnership with The American Society of Hematology (hematology.org), The ASH Trainee Council (https://www.hematology.org/education/trainees/fellows/trainee-council), and Hematopoeisis (https://www.hematology.org/education/trainees/fellows/hematopoiesis) ** Want to review the show notes for this episode and others? Check out our website. Love what you hear? Tell a friend and leave a review on our podcast streaming platforms!Twitter: @TheFellowOnCallInstagram: @TheFellowOnCallListen in on: Apple Podcast, Spotify, and Youtube

Join us for an inspiring and deeply informative episode featuring Dr. Christine N. Booth, the 2025–2026 President of the American Society of Cytopathology (ASC). Dr. Booth brings more than two decades of experience in cytopathology, breast pathology, and medical leadership, and currently serves as the Director of Regional Cytology at the Cleveland Clinic.  Whether you're a cytologist, pathologist, trainee, or simply fascinated by the science and stories behind cellular diagnostics, this episode offers a rare, engaging look at her leadership, why being active at the ASC is important, and the heart of cytopathology. Christine Booth, MD Cleveland Clinic ASC President   Terri Jones, MD University of Pittsburgh Medical Center (UPMC) Member, The ASC Bulletin & CytoPathPod Editorial Board

Trouble with bowel or bladder function? It might be time to partner with a specialist. In this episode of BackTable OBGYN, hosts Dr. Amy Park and Dr. Mark Hoffman are joined by Dr. Shannon Wallace and Dr. Anna Spivak, experts from the Cleveland Clinic specializing in pelvic floor disorders. They dive into the complex world of combined colorectal and urogynecological issues, discussing the importance of a multidisciplinary approach to treat conditions such as rectal prolapse, constipation, and incontinence. --- SYNPOSIS The conversation covers detailed diagnostic methods like manometry and defecography, various surgical options, and the crucial role of pelvic floor physical therapy in patient recovery. They also provide insights into setting up effective multidisciplinary clinics and emphasize the need for teamwork and administrative support in delivering optimal patient care. This episode is a valuable resource for both specialists and generalists aiming to enhance their understanding and treatment of pelvic floor dysfunctions. --- TIMESTAMPS 01:05 - Introduction05:40 - Multi-Compartment Prolapse & Second Opinions08:14 - Pelvic Floor Compartments Explained10:36 - When Internal Prolapse Becomes Surgical11:56 - Incomplete Emptying, Splinting, Fragmentation & Leakage16:55 - Fluoro vs MRI and When to Order It23:47 - Anorectal Manometry26:56 - Physical Therapy, Biofeedback, Meds, Injections, & Motility Workup29:08 - Robotic Mesh Repairs vs Vaginal/Perineal Approaches34:43 - When (and Why) to Consider Biologics36:46 - Resection Rectopexy38:10 - Treating Ehlers-Danlos syndromes (EDS) & Eating Disorders42:55 - Pelvic Floor PT After Surgery and Recovery Timelines47:29- Perineal Prolapse Repairs (Altemeier vs Delorme)49:53 - Symptom Improvement vs Retraining the 'New Normal'52:20 - Fecal Incontinence & Sacral Neuromodulation57:08 - Diarrhea-Driven Incontinence58:56 - Building a Multidisciplinary Pelvic Floor Program01:04:04 - Conclusion --- RESOURCES Pelvic Floor Disorders Consortium (American Society of Colon & Rectal Surgeons) https://fascrs.org/Web/Web/My-ASCRS/Education/Pelvic-Floor-Disorders-Consortium.aspx

Biologics have changed how patients with asthma are able to handle their symptoms and prevent them from getting worse. Host Amy Attaway, MD, Cleveland Clinic, talks with Monica Kraft, MD, Icahn School of Medicine at Mount Sinai, and De De Gardner, DrPh, Allergy and Asthma Network and member of PAR about depemokimab, the newest biologic for those with severe asthma. Learn how this novel treatment is used once every six months to improve patient outcomes, as well as the research behind this biologic and the future of asthma treatment. Read Dr. Kraft's paper on depemokimab: https://journal.chestnet.org/article/S0012-3692(25)00855-4/pdf  Editor's note: During this episode, Dr. Kraft mistakenly said that depemokimab was approved for treating nasal polyps. Please note that depemokimab is not approved for treating this condition. 

Send a textWhy are so many people dealing with chronic pain earlier than ever?In this episode, Dr. Kevin White sits down with Dr. Ashu Goyle, a double board-certified anesthesiology and pain medicine physician trained at the Cleveland Clinic and founder of Integrated Spine, Pain, and Wellness in Scottsdale, Arizona.Dr. Goyle shares how his philosophy shifted from simply interrupting pain signals to helping the body repair itself. They unpack why back pain, knee pain, and joint degeneration are rarely isolated problems, and why treating one body part without addressing sleep, nutrition, inflammation, stress, and biomechanics often leads to temporary relief instead of lasting change.They discuss regenerative approaches like PRP and other orthobiologic therapies, metabolic optimization before procedures, laser therapy, nervous system balance, and what it really takes to create an environment where healing can occur.“If you're going to put something powerful back into your body, make sure the environment you're putting it into is ready.”This conversation challenges the quick-fix mindset and reframes pain as part of a bigger story. If you want to stay strong, active, and capable as you age, this episode will change how you think about healing.Learn more about Dr. Ashu Goyle:Or find him on Instagram @DrAshuGoyleFollow The Daily Apple and leave a review to help more people find the show.www.primehealthassociates.com Instagram: @KevinWhiteMD YouTube: @KevinWhiteMD Prime Health Associates

If you or a loved one is coming to Cleveland for medical treatment, finding the right place to stay can make a difficult time much easier. In today's episode, Mike and Lindsey walkthrough what families should look for when booking housing near the Cleveland Clinic, including proximity, safety, first floor setups, pet friendly options, and why having flexible, supportive hosts matters when recovery timelines are uncertain. All this and more on the Cleveland Real Estate Investor Podcast.0:50 Mike opens by explaining why Cleveland is a world-class destination for medical care and what families should consider when booking housing for hospital stays.3:40 They break down the importance of proximity, safety, and quiet neighborhoods — plus why Airbnb-style stays work better than hotels for caregivers and visitors.7:20 Lindsey talks about pet-friendly housing, nearby grocery access, delivery options, and how location impacts comfort during long recoveries.11:45 Mike introduces their hospital-focused properties, highlighting first-floor setups, accessibility, and why the Carriage House is designed specifically for outpatient recovery.18:30 The episode wraps with flexibility in length of stay, customized housing needs, and why Mike and Lindsey aim to act like “extended family” during uncertain recovery timelines.

A 4-year-old little girl waiting for a heart at the Cleveland Clinic started flashing lights and writing signs to constructions workers across the way, and they started writing back! FULL STORY: https://www.wdjx.com/construction-workers-connect-with-little-patient-in-the-hospital/

In this episode of the PRS Global Open Keynotes podcast, the team from Ann and Robert H. Lurie Children's Hospital of Chicago, Illinois discuss how free AI tools can be used to convert plastic surgical textbooks into podcasts. This episode discusses the following PRS Global Open article: "Source-grounded Artificial Intelligence–Driven Transfer of Plastic Surgery Textbooks to Podcasts: Creation of Content and Trainee Satisfaction" by Iulianna Taritsa, Parul Rai, Anitesh Bajaj, Hannah Soltani and Arun K. Gosain. Read it for free on PRSGlobalOpen.com: https://journals.lww.com/prsgo/fulltext/2025/12000/source_grounded_artificial_intelligence_driven.21.aspx Dr. Arun Gosain is Professor of Pediatric Plastic and Reconstructive Surgery at the Northwestern University Feinberg School of Medicine at the Ann and Robert H. Lurie Children's Hospital of Chicago, Illinois. Hannah Soltani is senior medical student at the Northwestern Feinberg School of Medicine. Dr. Lulianna Taritsa is a plastic surgery resident at the Cleveland Clinic. Your host, Dr. Damian Marucci, is a board-certified plastic surgeon and Associate Professor of Plastic Surgery at the University of Sydney in Australia. #PRSGlobalOpen; #KeynotesPodcast; #PlasticSurgery; Plastic and Reconstructive Surgery- Global Open

In this episode of the Eye Believe Podcast, we're joined by Dr. Zack Oakey, a board-certified ophthalmologist and ocular oncologist with extensive training in retinal disease and ocular oncology.   Dr. Oakey shares his unique approach to using social media—especially TikTok—to educate patients, combat misinformation, and make complex ocular melanoma topics more accessible. Drawing from his training at institutions including the NIH, UC Irvine, the University of Wisconsin, and the Cleveland Clinic's Cole Eye Institute, he offers valuable insight into how trusted medical information can reach patients where they already are.   This episode blends medical expertise with modern communication, offering both reassurance and actionable information for patients, caregivers, and advocates alike.   Tune in to hear how education, accessibility, and innovation can make a real difference in the OM community.

In this podcast episode, an in-depth discussion is provided on the drug Telmisartan, commonly used for lowering blood pressure. The host elaborates on how it belongs to a class of medications known as angiotensin receptor blockers (ARBs) and stands out due to its 24-hour half-life and partial PPAR-gamma agonist activity.  The episode explores Telmisartan's potential benefits for longevity, including its properties that reduce cardiovascular mortality, renal decline, and metabolic issues. It also compares Telmisartan with other ARBs and addresses its unique ability to improve myocardial efficiency, reduce arterial stiffness, and support neuroprotection. Detailed explanations are given on technical concepts such as pulse pressure and its relevance to arterial compliance, and the necessity to consult a doctor before taking the medication is emphasized.   Telmisartan / ARBs (main topic) Telmisartan — MedlinePlus drug info: https://medlineplus.gov/druginfo/meds/a601249.html Blood pressure meds overview (includes ARBs): https://medlineplus.gov/bloodpressuremedicines.html Key mechanisms mentioned PPARγ (PPARG) — NCBI Gene: https://www.ncbi.nlm.nih.gov/gene/5468 Endothelium + nitric oxide (NO) — NCBI Bookshelf: https://www.ncbi.nlm.nih.gov/books/NBK534266/ Angiotensin / aldosterone / "fight-or-flight" Aldosterone test — MedlinePlus lab test: https://medlineplus.gov/lab-tests/aldosterone-test/ Sympathetic nervous system ("fight-or-flight") — Cleveland Clinic explainer: https://my.clevelandclinic.org/health/body/23262-sympathetic-nervous-system-sns-fight-or-flight Lab tests mentioned in the episode Fasting insulin ("Insulin in Blood") — MedlinePlus lab test: https://medlineplus.gov/lab-tests/insulin-in-blood/ Hemoglobin A1C (HbA1c) — MedlinePlus lab test: https://medlineplus.gov/lab-tests/hemoglobin-a1c-hba1c-test/ C-reactive protein (CRP) — MedlinePlus lab test: https://medlineplus.gov/lab-tests/c-reactive-protein-crp-test/ Arterial stiffness / pulse pressure (longevity framing) Pulse pressure & arterial stiffness as risk predictors — PubMed: https://pubmed.ncbi.nlm.nih.gov/11224702/ Visceral fat resource mentioned Dr. Sean O'Mara website: https://drseanomara.com/   Show Notes   00:00 Welcome to the Hart2Heart Podcast. 01:22 Understanding Angiotensin and Its Effects 02:14 How ARBs Work and Their Benefits 03:00 Unique Properties of Telmisartan 03:36 Comparing Telmisartan with Other ARBs 04:44 Telmisartan's Impact on Endurance and Fat Loss 05:59 Telmisartan and Cardiovascular Health 09:57 Blood Pressure Basics and Pulse Pressure 18:54 Telmisartan's Role in Longevity and Dosing 27:28 Conclusion and Final Thoughts   The Hart2Heart podcast is hosted by family physician Dr. Michael Hart, who is dedicated to cutting through the noise and uncovering the most effective strategies for optimizing health, longevity, and peak performance. This podcast dives deep into evidence-based approaches to hormone balance, peptides, sleep optimization, nutrition, psychedelics, supplements, exercise protocols, leveraging sunlight, and de-prescribing pharmaceuticals — using medications only when absolutely necessary. Beyond health science, we explore the intersection of public health and politics, exposing how policy decisions shape our health landscape and what actionable steps people can take to reclaim control over their well-being. Guests range from out-of-the-box thinking physicians such as Dr. Casey Means (author of "Good Energy") and Dr. Roger Sehult (Medcram lectures) to public health experts such as Dr. Jay Bhattacharya (Director of the National Institutes of Health (NIH) and Dr. Marty Mckary  (Commissioner of the Food and Drug Administration (FDA) and high-profile names such as  Zuby and Mark Sisson (Primal Blueprint and Primal Kitchen). If you're ready to take control of your health and performance, this podcast is for you.We cut through the jargon and deliver practical, no-BS advice that you can implement in your daily life, empowering you to make positive changes for your well-being.   Connect with Dr. Mike Hart Instagram: @drmikehart Twitter: @drmikehart Facebook: @drmikehart

Older Americans are struggling with social isolation more than ever.  This can lead to challenges with mental and physical health as people age, and one nonprofit is having great success trying to do something about it. Life Story Club uses scheduled Zoom and phone calls form members to share stories about their past, present, and plans for their future.  In this Blue Sky conversation, interim director and geriatric specialist Dr. Jennifer Wong describes how this life-changing organization operates.    Chapters: 00:00 Welcome and Jennifer's Background  The episode introduces Blue Sky and its focus on optimism, then introduces guest Dr. Jennifer Wong. Dr. Wong shares her journey into experimental psychology and her passion for supporting older adults and those with disabilities, which stems from personal experiences with family health challenges.  05:00 Life Story Club's Mission  Jennifer explains how she connected with the Life Story Club and describes its simple yet effective model. The club gathers older adults virtually each week to share life stories, aiming to combat social isolation and loneliness in a vulnerable population.  10:25 Story Rx Program and Partnerships  Jennifer details the Story Rx program, a unique initiative where medical professionals can prescribe Life Story Club to patients. This program allows for powerful partnerships with leading healthcare institutions like Cleveland Clinic and Montefiore, leveraging medical data to track the program's effectiveness in improving patient well-being.  15:22 Facilitator's Impact and Wisdom The discussion highlights the profound impact facilitators have and the valuable insights they gain from older adults' stories. Facilitators, who are paid professionals, often share their own vulnerabilities, fostering deep connections and mutual support within the clubs, which also incorporate geographical and linguistic considerations.  22:34 Intergenerational Perspective and Progress  Jennifer and Bill discuss how older adults' stories provide invaluable historical perspective, reminding younger generations of societal progress and the non-linear nature of change. These narratives offer optimism and a reminder that current challenges, while significant, have historical precedents that were overcome.  27:43 Data and Family Connection  Jennifer shares the impressive data collected from Life Story Club participants, showing significant improvements in loneliness, belonging, and mood. The conversation also emphasizes how the club's story recording feature provides a precious gift to families, reconnecting them with their elders' unheard stories and fostering intergenerational connection.  35:20 Growth and Future Outlook  Life Story Club is actively working on expanding its reach beyond New York, developing a working group for communities interested in replicating the model. They welcome partnerships with healthcare organizations and individual donors to meet the growing need for older adult support and enhance life for longer-living populations. 

Healthcare was supposed to protect families and small businesses—not bankrupt them. On this episode of Main Street Matters, Elaine Parker sits down with Dr. Firouz Daneshgari, a former surgeon-scientist and hospital board member at major health systems including Cleveland Clinic and University Hospitals, who became a whistleblower after witnessing firsthand how financial incentives began outweighing patient outcomes. With U.S. healthcare spending topping $5.6 trillion annually, Dr. Daneshgari explains: Why over half of healthcare spending may be waste How hospitals evolved into revenue-driven “sick care” systems Why employer-sponsored insurance distorted the doctor-patient relationship The hidden cost drivers behind rising premiums and medical debt How direct primary care and health “guardianship” models restore transparency and trust Why cash-pay pricing dramatically lowers specialty and surgical costs How small businesses can cut healthcare expenses without sacrificing quality What President Trump’s HSA subsidy proposal could mean for consumers Dr. Daneshgari shares how his BowTie Health Guardianship model combines subscription-based primary care, proactive chronic disease prevention, and upfront pricing to deliver affordable, high-quality care nationwide—without waiting for Congress to act. For small business owners struggling with rising premiums and unpredictable costs, this episode offers a real-world alternative that puts patients—not hospital systems—back in control.See omnystudio.com/listener for privacy information.

There is a bunch of tossing and turning in beds across the land. All in an effort to try to get to sleep.  And sleep is the one thing that affects all of us, whether you have an anxiety condition or not.  It is a two-fer. Your body needs it for repair and your brain needs it for cleaning and maintenance. So it is really important to make sure you have what you needs to set yourself up for a good night's sleep.   Especially if you have anxiety and depression type symptoms. This is an overview of what you need to get to sleep and keep it there for as long as you need it.  Resources Mentioned:  Australian Center of Clinical Inventions, there is a PDF handout on Sleep Hygiene with 15 tips on how to get a good night's sleep.   The U.S. non-profit health organization Kaiser Permanente has a page on why sleep is important and suggest that the only things you should do in bed is sleep and sex.    The National Sleep Foundation is an advocacy group for sleep health. They do have a section of their website that talks about the relationship between mental health and sleep.   I do need to let you know that there is another website call Sleep Foundation.org. This is a commercial site that reviews mattresses and sleep products. However they have a lot of info about sleep but they also are probably doing affiliate deals to support the website. The site does have factual information about sleep and sleep habits.   The Cleveland Clinic has a brief information page on weighted blankets.    And Harvard Health Publishing also has a page about weighted blankets with the statement that there isn't enough science research to indicate that they are helpful but people are using them for relief.   Emergency Resources The Trevor Project: Provides crisis support specifically for LGBTQ+ youth through phone (1-866-488-7386), text (START to 678-678), and online chat. Available 24/7. They also provide peer support and community.    Veterans Crisis Line: Call 988 and press 1, text 838255, or chat online. There are phone lines for those serving overseas. Visit the website to find the current status of the Veteran line and international calling options.    National Crisis Text Line: Text HOME to 741741 for free, confidential support 24/7. This service operates independently of the 988 service. Users can use text, chat or WhatsApp as a means of contact.   Disclaimer:  Links to other sites are provided for information purposes only and do not constitute endorsements.  Always seek the advice of a qualified health provider with questions you may have regarding a medical or mental health disorder. This blog and podcast is intended for informational and educational purposes only. Nothing in this program is intended to be a substitute for professional psychological, psychiatric or medical advice, diagnosis, or treatment.

Robert Kurland, Ph.D.Can AI Have a Soul? What Science Fiction SaysDr. Robert Kurland, a convert to Catholicism in 1995, is a retired physicist who has applied magnetic resonance to problems of biological interest in his research (web search: “Kurland-McGarvey Equation”). Dr. Kurland is a graduate of Caltech (BS, 1951, “with honor”) and Harvard (PhD, 1956). His scientific career at Carnegie-Mellon, SUNY/AB, Cleveland Clinic, Geisinger Medical Center, has focused on biological applications of magnetic resonance, including MRI. Since his conversion to Catholicism, he has tried to spread the message that there's no war between Catholic teaching and science.AbstractMuch before AI tools became available, science fiction stories had shown how it might be manifested in computers, robots, and humanoid androids. As with other Speculative Fiction (Tolkien, C.S. Lewis) one takes the contrapositive beings and situations in such tales not as possible reality, but as parables illustrating the human condition. Three stories will be discussed: “Deus X” in which human consciousness can be transplanted to computers as life after death“The Measure of a Man—Star Trek, Next Generation,” a trial to determine whether the android Data is more than a machine “Our Lady of the Artifacts,” a novel in which an android with superhuman capabilities is possessed by a devilFr. Robert J. Spitzer, S.J., Ph.D.Why AI Can't Have a Soul: The Transphysical ParadoxFor more on Magis AI, see https://wcatradio.com/wp-content/uploads/2026/02/MagisAI.pdfFr. Robert J. Spitzer, S.J., Ph.D. is President of the Magis Center of Reason and Faith (magiscenter.com), one of the largest science, faith, and reason apologetics institutes in the world. He was President of Gonzaga University from 1998 to 2009, where he increased the student body by 75%, oversaw the construction of 20 new facilities, and raised $200+ million for scholarships and buildings. He is the author of nineteen books, including the award-winning books New Proofs for the Existence of God and Science, Reason, and Faith: Discovering the Bible. He has also authored many scholarly articles on faith and science, metaphysics, and happiness and ethics. Father Spitzer has his own weekly EWTN television show called Fr. Spitzer's Universe. He has appeared on the Larry King Show (in discussion with Stephen Hawking and Deepak Chopra), the History Channel, the Today Show, and a PBS series. He started seven institutes dedicated to faith and reason and happiness/purpose in life. He was a professor at Georgetown University, Seattle University, and Gonzaga University and was awarded the teaching medal at both Georgetown University and Seattle University. He has held two major academic chairs—the Frank Shrontz Endowed Chair in Professional Ethics (Seattle University) and the John L. Aram Chair of Business Ethics (Gonzaga University), and has won multiple academic and professional awards including the DeSmet Medal (Gonzaga University's highest award), the Aquinas Medal (for Catholic philosophical scholarship), honorary doctorates, Phi Beta Kappa (honorary), and professional society awards.AbstractThe human soul performs five functions that cannot be reduced to physical processes and structures: (1) Self-consciousness, (2) Abstract intellection through conceptual ideas, (3) Conscience and moral awareness, (4) Transcendental awareness, and (5) Spiritual-numinous awareness. Since AI is reducible, and will always be reducible to physical processes and structures, AI will not replace a human soul – or be like a human soul.

This is the Weight and Healthcare newsletter! If you like what you are reading, please consider subscribing and/or sharing!In Part 1 we started discussing the “Million Pound Challenge” created by Toby Cosgrove and Dr. Michael Roizen in which they are “challenging” an unknown number of people to collectively lose one million pounds. In part 2 we'll discuss the program itself. (If you haven't read part 1, I recommend it to fully understand part 2.) As always I'll indent the quotes from the website so that you can avoid harmful weight stigma if you choose. They explain the program as a 3-step process:Step 1: Enroll Your OrgRegister your health system. Get access to a variety of resources in the Million Pound Challenge Tool Kit for your entire team.Step 2: Your Staff, Your WayEmployees can use the tools provided, join their own programs, work with providers—whatever works. Your organization decides how to structure participation.Step 3: Track ProgressThe only requirement? Track results with a monthly check with your Challenge coordinator. Watch as individual effort becomes collective momentum toward one million pounds.This is where they make things incredibly clear - literally the only requirement is to track weight loss. This isn't about health metrics, there is no way to make this program weight neutral or to focus on health - weight loss is the only metric and tracking it is the only thing the program requires.And when they blithely say “whatever works” let's be clear that a century of research finds that, unless their goal is to create weight cycling, nothing does. So there is no common intervention and all they are tracking is weight loss. Right. And how is weight loss tracked? Per the FAQs (emphasis mine)“Your Challenge ambassador must log your team's results monthly with your assigned Challenge Coordinator—this is the only requirement. Individual weights remain completely private. Only aggregate organizational totals are posted on the community leaderboard so you can see how your organization compares nationally.”Um, they aren't private if you have to share them with your company's challenge ambassador (and I have serious concerns that someone who would sign up for that job may be the last person that a coworker would want to tell their weight.) Workplace programs (or any programs) that include a weight loss component have significant risks to physical and mental health, including through eating disorders. But programs that compel people to compete solely on the basis of weight loss, as this one does, can actually encourage participation in dangerous behaviors in order to create weight loss.Measure your organization's progress, celebrate your success stories, and recognize your top-performing teams. Join leaders at quarterly events, Chamber Summit, Aspen Ideas Festival, and HLTH to keep momentum strong.Do. Not. Do. This. Another huge issue with this, and all workplace/organization weight-loss challenges, besides the issues with disordered eating and eating disorders and weight cycling, is that it can single out people who aren't participating or “achieving” in ways that create a hostile work environment for them. It can mean that those who have chosen an evidence-based weight-neutral path (either due to a history of eating disorders or other reasons) have to choose between their physical and mental health and being seen as “not a team player.” It can lead to organizations under valuing employees who, due to many reasons including disability, chronic illness, and more, cannot participate in the initiative at all (or in ways that make them “top-performing”) which can lead them to being seen by subordinates, peers, and bosses as a “drag” on the team or having less value to the organization. This is not surprising from someone like program co-founder Toby Cosgrove who once gleefully told the New York Times magazine that he didn't want to hire higher-weight people (as the CEO of the Cleveland Clinic,) but let's not follow in those bigoted footsteps.After 12 months, we'll have collectively proven what we've known all along—that sustainable health outcomes are achievable. Winners celebrated at HLTH 2026. Every organization recognized for leading the revolution.There is so much wrong with this that I scarcely know where to begin. As I said in part 1, “prove” is a very strong word so I expect robust research and lots of it (spoiler alert - I'm going to be disappointed again, but in no way surprised, again.) These two doctors should know better than to suggest that anything about “sustainable health outcomes” can be “proven” by a random “challenge” that only lasts a year has no common intervention, and only measures weight loss. This does not have the ring of sound science. The truth is, we can't even be sure how many of the participants would get thin enough that program co-founder Toby Cosgrove would think they deserved to be employed.I don't want to spend too much time analyzing the deck chairs on this titanic of a “challenge” but I do want to look at one of the “resources” they offer, called ‘Why Healthy Employees Don't Need Your Wellness Challenge.” First of all remember that this is NOT a wellness challenge (which would measure, you know, wellness) this is a weight loss challenge that only measures body size manipulation. Even if we ignore that, this “resource” is particularly horrifying, promoting the “Lifestyle 180” program. The program is based on the assumption that higher-weight people and those with chronic conditions are not already participating in health-supporting behaviors and should be “targeted”, by their employers (not their actual healthcare providers,) with “intensive, medically-integrated interventions.”Here again, this program teaches organizational leadership to see higher-weight people and those with chronic conditions as a liability to be solved and not as skilled and valuable employees, with the unspoken (except by Toby to the NYT magazine) takeaway to avoid hiring these people in the first place. This is likely to disproportionally impact higher-weight people, People of Color, and especially higher-weight People of Color. (Note that this is all wrapped up in the massive issues with U.S. employers providing healthcare which is, to use a technical term, a hot garbage mess that is beyond the scope of this post, but the idea that employers should have access to employee health information is obviously seriously problematic on its face.) The “resource” continuously suggests that employers focus on “the 20% of [ employees] driving 80% of the costs” ending with “that's where you win.”My main takeaway from this resource was that if an employer sent me an email that said “Your recent health screening showed some concerning trends We have a program specifically designed for you. Can we talk?” I should say, emphatically, no. Which would also be my immediate answer if asked to participate in this “challenge.”In Part 3 we'll talk about what you can do if your organization tries to push this kind of “challenge” on you.This month's online workshop is Weight-Neutral Joint Pain Management with sports medicine physicians Dr. Julia Bruene and Dr. Jeremy Alland. There is a pay-what-you-can-afford option and a video will be sent to all registrants.Details and registration here!If you appreciate the content here, you can subscribe for free to get future posts delivered direct to your inbox, or choose a paid subscription to support the newsletter (and the work that goes into it!) and get special benefits! Click the Subscribe button below for details:Liked the piece? Share the piece!More researchThe Research PostMore resourcesThe Resource Post*Note on language: I use “fat” as a neutral descriptor as used by the fat activist community, I use “ob*se” and “overw*ight” to acknowledge that these are terms that were created to medicalize and pathologize fat bodies, with roots in racism and specifically anti-Blackness. Please read Sabrina Strings' Fearing the Black Body – the Racial Origins of Fat Phobia and Da'Shaun Harrison's Belly of the Beast: The Politics of Anti-Fatness as Anti-Blackness for more on this. Get full access to Weight and Healthcare at weightandhealthcare.substack.com/subscribe

Host Lisa Salberg is joined by Dr. Milind Desai of Cleveland Clinic to discuss new research challenging how hypertrophic cardiomyopathy patients define “asymptomatic.” They break down what long-term data and stress testing reveal about hidden symptoms, why follow-up matters even when you feel well, and how new therapies are reshaping care during a rapidly evolving era in HCM treatment.   This conversation was recorded Jan. 30, 2026.

Federal judge blocks the Trump administration's attempt to end Temporary Protected Status for Haitian migrants, including an estimated 15,000 in Springfield; Columbus man arrested in the disappearance and death of an Indianapolis-area teen; prolonged cold spell is causing water main breaks and service disruptions in Cincinnati; Cleveland Clinic docs say housework is good for your health.

The Cleveland Clinic rejects politics, sticks with science on childhood vaccines Learn more about your ad choices. Visit megaphone.fm/adchoices

In today's episode, the discussion features Sikander Ailawadhi, MD, and Beth Faiman, CNP, PhD, who provided clinical perspectives on the ongoing development of subcutaneous isatuximab-irfc (Sarclisa) administration via an on-body injector for patients with multiple myeloma. Dr Ailawadhi is a professor of medicine, a consultant in the Division of Hematology/Oncology in the Department of Internal Medicine, and a consultant in the Department of Cancer Biology at the Mayo Clinic Comprehensive Cancer Center in Jacksonville, Florida. Dr Faiman is a nurse practitioner in the Department of Hematology/Oncology at Cleveland Clinic and a member of the Cancer Prevention, Control and Population Research Program at the Case Comprehensive Cancer Center, both in Cleveland, Ohio. 

Send us a textForget the assumption that modern neurology only thrives where resources are abundant. We sit down with Dr. Daniel Ontaneda and Dr. Nelson Maldonado—two Ecuadorian neurologists driving change across Latin America—to explore how world-class care is built on clinical craft, cultural fluency, and relentless advocacy. From bedside localization when the MRI is down to expanding stroke thrombolysis from a handful of cases to hundreds, their stories reveal a system where expertise is abundant but access can lag—and how that gap is closing.We retrace Dan's journey from Quito to leading-edge MS research, and Nelson's decision to return home to build services few believed possible. Together they unpack what training looks like across the region, including long-format medical school, rural service, and residencies that demand deep exam skills. We compare public and private systems in Ecuador, break down why patients often want clear directives rather than options, and examine how cultural beliefs and language shape adherence. The conversation digs into MS treatment in low- and middle-resource settings, the rise of highly effective disease-modifying therapies, and the pragmatic use of cost-effective options like rituximab.The episode also exposes a hidden threat: substandard medications entering through price-first procurement, undermining both acute care and chronic neurologic disease. Yet the momentum is real—regional MS registries, imaging collaborations that move faster than heavily regulated systems, and conferences that bring neurocritical care and MS experts under one roof. Even subspecialists practice broadly, treating Parkinson's disease, epilepsy, headache, and ICU cases in the same week, sharpening an exam-first mindset that delivers results.If you care about global neurology, stroke systems of care, MS access, and the practical ethics of delivering evidence-based treatment under constraints, this conversation will challenge assumptions and spark ideas. Subscribe, share with a colleague, and leave a review telling us where neurology should invest next.Support the showHosts:Dr. Nupur Goel is a third-year neurology resident at Mass General Brigham in Boston, MA. Follow Dr. Nupur Goel on Twitter @mdgoels Dr. Blake Buletko is a vascular neurologist and program director of the Adult Neurology Residency Program at the Cleveland Clinic in Cleveland, OH. Follow Dr. Blake Buletko on Twitter @blakebuletko Follow the Neurophilia Podcast on Twitter and Instagram @NeurophiliaPod

For weeks, the nation's flashpoint over immigration and enforcement has been Minneapolis where two protesters have now been shot dead by federal immigration officers. Concern is now ramping up in Ohio, where there's concern that a surge of immigration enforcement is coming to Springfield, near Dayton. The temporary protected status of thousands of Haitian refugees living there is set to expire on Feb. 3. We will begin Friday's “Sound of Ideas Reporters Roundtable” with a discussion in how leaders are preparing for a possible enforcement in Ohio. Jury selection began this week in the trial of two former FirstEnergy executives accused of being the architects of the House Bill 6 bribery scandal in which they bribed politicians and got legislation passed that bailed out their financially struggling nuclear power plants. The trial is expected to last for two months and opening statements could happen as soon as Jan. 30. The deep freeze over the last week will stay around, without an invitation, as we flip to February. It's the longest stretch of arctic temperatures we've seen here in years. The deep cold also made it tough to dig out from last weekend's heavy snowstorm and complicated plowing roads. A combination of the numbing cold and icy roads led to schools closing for several days. Will students have to make up those days? During this cold weather, owners have been warned in several Ohio counties -- including Summit and Cuyahoga -- to bring animals indoors. Cuyahoga County's prosecutor has formed a specialized unit to deal with that, and other kinds, of animal cruelty. Northeast Ohio cities are starting to see the boon promised by the sale of recreational marijuana, legalized by voters in 2023. Sales began the next year, and cities are now seeing the first proceeds from the first year-plus of sales. Dr. Tom Mihaljevic, president and chief executive officer of the Cleveland Clinic, said the Clinic made money last year and did better financially than forecasted, and said he believes there is capacity in the community for the Clinic to build a Level 1 trauma center, though there are already two in Cleveland. Guests: -Andrew Meyer, Deputy Editor for News, Ideastream Public Media -Zaria Johnson, Reporter, Ideastream Public Media -Karen Kasler, Statehouse News Bureau Chief, Ohio Public Radio/TV

My guest today on the Online for Authors podcast is Leslie R Schover, author of the book Fission. Leslie is a clinical psychologist and brings her knowledge of people and relationships to her fiction writing. She spent most of her career at the Cleveland Clinic and the M. D. Anderson Cancer Center. She published three self-help books and created a digital health company to educate people with cancer about sex and fertility. Will2Love.com won a 2019 Innovation Prize in the Astellas C 3 Changing Cancer Care contest. Her first published novel, Fission: A Novel of Atomic Heartbreak draws on her parents' stories of Oak Ridge during the Manhattan Project and on revelations of Soviet spies there. She lives in Houston, Texas with her faithful dog, Luc.   In my book review, I stated that Fission is a wonderful historical fiction. Although set during WWII, this book takes place completely within the United States as we follow Doris and her husband Rob to Oak Ridge, Tennessee. Doris' husband is tapped to work on the Manhattan Project, a top-secret program to create the first atomic bomb.   As a reluctant young mother and bride, Doris first has to decide if she will move to Oak Ridge or continue her education. When she finally moves to Oak Ridge, she has to figure out her place in a world very different from Chicago. Will being Jewish be something to overcome? Will her husband's lack of education stop him from advancing? Will Doris figure out her role as wife and mother? What will she do when romance comes knocking - and not from her husband?   I was excited to learn this story is based loosely on Leslie's parents, which gives an emotional edge to the characters - and you know how I love a good character! This is a must-read book that will give you an insider's look at The Manhattan Project and how it affected not just the scientists, but all who lived and worked in Oak Ridge.   Subscribe to Online for Authors to learn about more great books! https://www.youtube.com/@onlineforauthors?sub_confirmation=1   Join the Novels N Latte Book Club community to discuss this and other books with like-minded readers: https://www.facebook.com/groups/3576519880426290   You can follow Author Leslie R Schover Website: https://www.leslieschoverauthor.com/ IG: @leslieschover FB: @leslie.schover.9   Purchase Fission on Amazon: Paperback: https://amzn.to/4rRR3dp Ebook: https://amzn.to/48Cb92k   Teri M Brown, Author and Podcast Host: https://www.terimbrown.com FB: @TeriMBrownAuthor IG: @terimbrown_author X: @terimbrown1   Want to be a guest on Online for Authors? Send Teri M Brown a message on PodMatch, here: https://www.podmatch.com/member/onlineforauthors   #leslierschover #fission #historicalfiction #terimbrownauthor #authorpodcast #onlineforauthors #characterdriven #researchjunkie #awardwinningauthor #podcasthost #podcast #readerpodcast #bookpodcast #writerpodcast #author #books #goodreads #bookclub #fiction #writer #bookreview *As an Amazon Associate I earn from qualifying purchases.

Ruth is learning, writing, and teaching about thyroid disease in lots of different places, so IHACW is coming along for the ride. Hypothyroidism: the thyroid gland doesn't produce enough of the right hormones to stimulate healthy metabolism—a person has a hard time turning fuel (that's oxygen and food) into energy. The result: lethargy, weight gain, sluggish digestion, and lots, lots more. Does this describe any of your clients? But treating endocrine diseases is a tricky business. In this episode Ruth interviews a friend who had some success, but it is an ongoing battle. Resources: Allen, E. and Fingeret, A. (2025) "Anatomy, Head and Neck, Thyroid," in StatPearls. Treasure Island (FL): StatPearls Publishing. Available at: http://www.ncbi.nlm.nih.gov/books/NBK470452/ (Accessed: January 1, 2026). Elshimy, G. et al. (2025) "Myxedema Coma," in StatPearls. Treasure Island (FL): StatPearls Publishing. Available at: http://www.ncbi.nlm.nih.gov/books/NBK545193/ (Accessed: January 8, 2026). Lu, M. et al. (2025) "Therapeutic benefits of acupoint massage at Yuji (LU10) and Zhaohai (KI6) for postoperative hoarseness in thyroid surgery patients," BMC surgery, 25(1), p. 148. Available at: https://doi.org/10.1186/s12893-025-02889-7. Rosen, J.E. et al. (2013) "Complementary and alternative medicine use among patients with thyroid cancer," Thyroid: Official Journal of the American Thyroid Association, 23(10), pp. 1238–1246. Available at: https://doi.org/10.1089/thy.2012.0495. Tachi, J., Amino, N. and Miyai, K. (1990) "Massage therapy on neck: a contributing factor for destructive thyrotoxicosis?," Thyroidology, 2(1), pp. 25–27. Thyroid Nodules: Causes, Symptoms & Treatment (no date) Cleveland Clinic. Available at: https://my.clevelandclinic.org/health/diseases/13121-thyroid-nodule (Accessed: January 8, 2026). Thyroid: What It Is, Function & Problems (no date). Available at: https://my.clevelandclinic.org/health/body/23188-thyroid (Accessed: January 1, 2026). Wyne, K.L. et al. (2023) "Hypothyroidism Prevalence in the United States: A Retrospective Study Combining National Health and Nutrition Examination Survey and Claims Data, 2009–2019," Journal of the Endocrine Society, 7(1), p. bvac172. Available at: https://doi.org/10.1210/jendso/bvac172. Sponsors: Anatomy Trains is a global leader in online anatomy education and also provides in-classroom certification programs for structural integration in the US, Canada, Australia, Europe, Japan, and China, as well as fresh-tissue cadaver dissection labs and weekend courses. The work of Anatomy Trains originated with founder Tom Myers, who mapped the human body into 13 myofascial meridians in his original book, currently in its fourth edition and translated into 12 languages. The principles of Anatomy Trains are used by osteopaths, physical therapists, bodyworkers, massage therapists, personal trainers, yoga, Pilates, Gyrotonics, and other body-minded manual therapists and movement professionals. Anatomy Trains inspires these practitioners to work with holistic anatomy in treating system-wide patterns to provide improved client outcomes in terms of structure and function.                      Website: anatomytrains.com     Email: info@anatomytrains.com           Facebook: facebook.com/AnatomyTrains         Instagram: www.instagram.com/anatomytrainsofficial YouTube: https://www.youtube.com/channel/UC2g6TOEFrX4b-CigknssKHA    Precision Neuromuscular Therapy seminars (www.pnmt.org) have been teaching high-quality seminars for more than 20 years. Doug Nelson and the PNMT teaching staff help you to practice with the confidence and creativity that comes from deep understanding, rather than the adherence to one treatment approach or technique. Find our seminar schedule at pnmt.org/seminar-schedule with over 60 weekends of seminars across the country. Or meet us online in the PNMT Portal, our online gateway with access to over 500 videos, 37 NCBTMB CEs, our Discovery Series webinars, one-on-one mentoring, and much, much more! All for the low yearly cost of $167.50. Learn more at pnmt.thinkific.com/courses/pnmtportal!  Follow us on social media: @precisionnmt on Instagram or at Precision Neuromuscular Therapy Seminars on Facebook.   Heights Wellness Retreat is redefining whole-body wellness through an innovative, integrated approach to physical, mental, and emotional well-being. Built on more than two decades of Massage Heights expertise in massage and skin therapy, this next-generation wellness destination represents the evolution of our mission to transform lives through wellness.  At Heights Wellness Retreat, we believe every person is an unstoppable force, whether navigating daily demands, pursuing goals, or striving to be their best. This drives everything we do. We go beyond traditional spa services by creating a purpose-driven environment where wellness professionals are empowered, valued, and positioned to grow. With steady clientele, support, and a wellness-forward culture, Heights Wellness Retreat is where therapists build meaningful, sustainable careers while shaping the future of the wellness industry.  www.massageheightscareers.careerplug.com/jobs  www.heightswellnessretreats.com  https://www.instagram.com/heightswellnessretreat/  https://www.facebook.com/heightswellnessretreat/   

Healthcare is undergoing profound transformation, and few leaders have had a closer view of that evolution than Kelly Hancock, Executive Vice President, Chief Caregiver Officer and Chief Administrative Officer at Cleveland Clinic. With more than 30 years of experience—from bedside nursing to executive leadership—Kelly reflects on the moments that shaped her purpose and the mission-driven culture she champions today. In this episode, Kelly unpacks the most critical issues impacting healthcare right now: workforce shortages, caregiver burnout, retention, resilience, and the shifting expectations of today's clinical workforce. She highlights innovative programs like peer support networks, holistic wellbeing initiatives, and apprenticeship pathways that are redefining how health systems attract, support, and grow talent. Looking ahead, Kelly explores the role of emerging technologies—including AI, predictive analytics, and clinical command centers—in enhancing operations while preserving human-centered care. Her insights offer a clear, grounded vision for what the future of caregiving should look like—and how leaders can build stronger, more connected teams in a rapidly changing healthcare landscape.

Our readers say this moment in U.S. history is like no other, and the future of democracy is at stake if citizens don't stop the march of fascism now. Learn more about your ad choices. Visit megaphone.fm/adchoices

Dr. Margarita Fedorova discusses possible environmental exposures and their risk of Parkinson disease.  Show citation:  Dorsey ER, De Miranda BR, Hussain S, et al. Environmental toxicants and Parkinson's disease: recent evidence, risks, and prevention opportunities. Lancet Neurol. 2025;24(11):976-986. doi:10.1016/S1474-4422(25)00287-X  Show transcript:  Dr. Margarita Fedorova: Welcome to Neurology Minute. My name is Margarita Fedorova and I'm a neurology resident at the Cleveland Clinic. Today, we're reviewing some information about possible environmental exposures and their risk of Parkinson disease. As we see in diagnose patients with Parkinson, they often want to know why they developed it and some emerging studies may offer insights. A recent personal view published in The Lancet Neurology by Ray Dorsey and colleagues in November 2025 examined associations between three environmental exposures and Parkinson's disease; pesticides, dry cleaning chemicals and air pollution. Since only five to 15% of Parkinson's cases have an identifiable genetic cause, environmental factors are an important area of investigation. Dorsey and colleagues describe studies showing that pesticide exposure is associated with Parkinson's risk. One example is Paraquat, an herbicide widely used in agriculture. It's banned in over 30 countries, but remains legal in the United States. In a population-based US study, residents living or working near areas where Paraquat was sprayed at twice the risk of developing Parkinson's, suggesting residential proximity alone may confer risk. Other pesticide exposures may show similar patterns. The organic chlorides, DGT and gildren are used in various agricultural areas. They're fat-soluble compounds that accumulate over decades. Postmortem studies found that when brains with lewd pathology and some studies suggest developmental exposure may increase risk of neurodegeneration years later. There have also been risks possibly associated with chemicals used in dry cleaning and metal degreasing. Trichloroethylene or TCE is one such chemical that was found in high amounts in the water at Camp Lejeune in North Carolina. A study of over 170,000 marines stationed there showed a 70% increase in risk of developing Parkinson's compared to marines at a non-contaminated base. What's particularly striking is the timing. Marines were exposed at an average age of 20 and the exposure lasted just over two years, yet disease manifested 34 years later. This suggests a long latency period between exposure and disease onset. TCE is also concerning because it evaporates from contaminated groundwater and can seep into buildings. As of 2000, 30% of US groundwater was contaminated with TCE. The third category of environmental exposure is air pollution. Studies from Canada, South Korea, Taiwan, and the UK show association between exposure to fine particular matter known as PM 2.5 in nitrogen dioxide with increased Parkinson's risk. These pollutants come from vehicle emissions, industrial sources, and combustion processes. The studies suggest that chronic exposure to these air pollutants may contribute to neurodegeneration through inflammatory and oxidative stress mechanisms. Unlike pesticides and dry cleaning chemicals, the magnitude of increased risk is often modest, typically ranging from one to 20%. However, the potential impact at large since almost everyone worldwide, 99% of people breathe on healthy air. For us as clinicians, this underscores the importance of taking detailed environmental histories. When patients ask, "Why me?" We can acknowledge that environmental exposures may have contributed to their disease. It's important to note that these studies show associations, but they don't confirm clear causation. Regardless, they may provide some answers to patients asking about the etiology of their Parkinson's or even the risks to others. That's your neurology minute for today. Keep exploring and we'll see you next time. If you want to read more, please find the paper by Ray Dorsey, titled Environmental Toxicants and Parkinson's Disease: Recent Evidence and Prevention Opportunities, published online in The Lancet Neurology in November 2025.

This week on The Bend Show from the “house burping” home trend to dumb outdoor criminal stories and how winter weather can trigger migraines. Join radio hosts Rebecca Wanner aka ‘BEC' and Jeff ‘Tigger' Erhardt (Tigger & BEC) with the latest in Outdoors & Western Lifestyle News! Home Trends, Outdoor Headlines & Health Impacts of Winter Weather House Burping: Why Some Homeowners Are Opening Windows in Winter Even as winter temperatures plunge, a growing number of homeowners are opening their windows on purpose — a trend known as “house burping.” The idea comes from a long-standing German practice called lüften, which simply means airing out your home to improve indoor air quality. Air quality experts say it can actually be healthy. Letting in fresh air helps reduce moisture, mold, carbon dioxide, and indoor pollutants — especially important since Americans spend about 90 percent of their time indoors. In Germany, lüften is so common that some rental agreements even require tenants to open windows regularly. The practice has gone viral in the U.S., with social media users sharing routines like airing out the house first thing in the morning, after cooking or showering, or after guests leave. There are downsides, though. Critics say opening windows in winter can hurt energy efficiency and drive up heating costs. Experts recommend keeping it short — about ten minutes is all it takes. So while it may feel counterintuitive, a quick blast of cold air could help keep your home healthier — just don't leave those windows open too long. Reference: https://www.today.com/life/what-is-house-burping-benefits-rcna255170 Outdoors Hunting & Fishing Dumb Crimes According to Outdoor Life, A former Alaskan guide with a long history of wildlife violations has once again been found guilty—this time for crimes tied to his commercial fishing business. Fifty-one-year-old Michael Patrick Duby of Juneau was convicted by a jury on January 15 of multiple charges, including falsifying commercial fishing records, selling fish taken for personal use, fishing out of season, and harvesting clams without a permit. Duby's record of fish and game violations stretches back more than 20 years. In 2012, he received one of Alaska's harshest sentences for wildlife crimes after a federal investigation found he illegally killed and sold protected birds. That case, along with other state offenses, cost him his hunting and sport fishing privileges, landed him in prison, and resulted in tens of thousands of dollars in fines. After losing those privileges, Duby shifted into commercial fishing, saying it was still his passion. But prosecutors say the pattern continued. His most recent convictions stem from actions in 2019 and 2020 while operating Genesis Seafoods, including felony charges for falsifying harvest records and reckless endangerment for selling untested clams. State prosecutors have described Duby as someone unable to stop breaking fish and game laws. His wife, who was charged as an accomplice and is a state fish and game operations manager, was acquitted. Patrick Duby represented himself at trial and is scheduled to be sentenced in May. Reference: https://www.outdoorlife.com/conservation/alaska-poacher-turned-commercial-fisherman-convicted/ Bronze Bighorn Stolen from Kuiu HQ—And the Getaway Didn't Go as Planned Two masked thieves targeted the Kuiu headquarters in Dixon, California, but their bold plan hit a snag—they couldn't fit what they stole into their car. In the early morning hours of December 31, surveillance video shows the suspects sawing a life-sized bronze bighorn sheep statue off its concrete base using a battery-powered saw. After tipping the heavy statue over, the pair struggled to load it into the backseat of what appears to be a Chrysler 300. When that didn't work, they left the scene, returned about 15 minutes later with a luggage cart, and wheeled the statue away. Police believe the bronze ram was later cut into smaller pieces so it could be transported and likely sold for scrap. The statue, nicknamed “Rocky,” had been installed outside Kuiu's headquarters just months earlier, in June of 2024. Bronze scrap currently sells for only a few dollars per pound, but thefts of bronze artwork are reportedly on the rise. Kuiu has released the surveillance footage and is offering a $5,000 reward for information leading to an arrest. The case is being handled by the Dixon Police Department, and the company says the response online has been immediate and overwhelming. Reference: https://www.outdoorlife.com/conservation/thieves-steal-kuiu-sheep-statute/ Missouri Offers $15,000 Reward in Bull Elk Poaching Case Missouri conservation officials are asking for the public's help after a bull elk was illegally shot and killed at Peck Ranch Conservation Area in southern Missouri. The Missouri Department of Conservation is offering a fifteen-thousand-dollar reward for information leading to an arrest and conviction. The adult bull elk was discovered the morning of November 26, 2025, lying dead in an open field with a gunshot wound to the left shoulder. Investigators say evidence at the scene shows the shooter drove a vehicle directly into the field toward the elk, then circled back onto a gravel trail and left the area at a high rate of speed. Tire tracks entering and exiting the field were clearly visible. Photos submitted by members of the public helped narrow down the timeline. One photo shows the elk alive and grazing around 5:15 the evening before. Another photo taken just after 8:00 the next morning shows the animal dead in the same field. The case is being handled through Missouri's Operation Game Thief program, which emphasizes that poaching hurts wildlife conservation efforts and the hunters who follow the law. Anyone with information is urged to call 800-392-1111. Tips can be made anonymously, and conservation officials say even small details could help bring the person responsible to justice. Reference: https://www.outdoornews.com/2026/01/20/missouri-offers-15k-reward-for-help-in-elk-poaching-case/ How Winter Weather Can Trigger Migraines — and What You Can Do  As winter weather settles in, doctors say colder temperatures and changing weather patterns may be triggering more migraines. According to a Cleveland Clinic headache specialist, sudden shifts in barometric pressure can create pressure changes in the sinuses, which may set off migraines in people who are already prone to them. Extreme cold can also be a factor. For those sensitive to winter temperatures, simply being out in frigid air can increase the chances of a migraine starting. There are steps you can take to help prevent winter-related migraines. On very cold days, staying indoors when possible can help. If you do head outside, bundle up — especially covering your head and neck to limit cold exposure. Doctors also recommend keeping migraine medications with you, so you can treat symptoms early. Beyond the weather, lifestyle habits matter. Getting enough sleep, staying active, managing stress, and addressing anxiety or depression can all play a role in reducing migraine frequency. And if migraines start interfering with daily life, Cleveland Clinic experts say it's time to talk with your doctor, who can help find the right treatment plan to better manage symptoms through the winter months. Reference: https://newsroom.clevelandclinic.org/2026/01/02/winter-weathers-impact-on-migraines OUTDOORS FIELD REPORTS & COMMENTS We want to hear from you! If you have any questions, comments, or stories to share about bighorn sheep, outdoor adventures, or wildlife conservation, don't hesitate to reach out. Call or text us at 305-900-BEND (305-900-2363), or send an email to BendRadioShow@gmail.com. Stay connected by following us on social media at Facebook/Instagram @thebendshow or by subscribing to The Bend Show on YouTube. Visit our website at TheBendShow.com for more exciting content and updates! https://thebendshow.com/ https://www.facebook.com/thebendshow WESTERN LIFESTYLE & THE OUTDOORS Jeff ‘Tigger' Erhardt & Rebecca ‘BEC' Wanner are passionate news broadcasters who represent the working ranch world, rodeo, and the Western way of life. They are also staunch advocates for the outdoors and wildlife conservation. As outdoorsmen themselves, Tigger and BEC provide valuable insight and education to hunters, adventurers, ranchers, and anyone interested in agriculture and conservation. With a shared love for the outdoors, Tigger & BEC are committed to bringing high-quality beef and wild game from the field to your table. They understand the importance of sharing meals with family, cooking the fruits of your labor, and making memories in the great outdoors. Through their work, they aim to educate and inspire those who appreciate God's Country and life on the land. United by a common mission, Tigger & BEC offer a glimpse into the life beyond the beaten path and down dirt roads. They're here to share knowledge, answer your questions, and join you in your own success story. Adventure awaits around the bend. With The Outdoors, the Western Heritage, Rural America, and Wildlife Conservation at the forefront, Tigger and BEC live this lifestyle every day. To learn more about Tigger & BEC's journey and their passion for the outdoors, visit TiggerandBEC.com. https://tiggerandbec.com/

The idea might seem like something out of a fantasy, but “Foreign Accent Syndrome” is a genuine, albeit very rare, neurological condition! It sees a person begin to speak with an accent different to the one they had prior to having a stroke; one which makes them sound like they come from an entirely different country! Since the first case was discovered in France in 1907, there have only been about 100 documented cases worldwide, according to the Cleveland Clinic. But certain cases have attracted the attention of the media and scientific researchers alike. One dates back to 1941 in Oslo, Norway, during a period of German occupation.  What is the foreign accent syndrom? What exactly happens in the brain in such cases? How serious can the syndrome be? In under 3 minutes, we answer your questions! To listen to the last episodes, you can click here: ⁠⁠⁠How to spot, prevent and treat heatstroke ?⁠⁠⁠ ⁠⁠⁠What are the strangest reactions caused by an orgasm?⁠⁠⁠ ⁠⁠⁠How can I learn 1000 words in a new language?⁠⁠⁠ A podcast written and realised by Amber Minogue. First Broadcast: 10/1/2025 Learn more about your ad choices. Visit megaphone.fm/adchoices

Managing heart failure isn't just about medications. It's about the everyday food choices that can either ease the strain on your heart or quietly make symptoms worse.In this episode, we break down why sodium has such a powerful impact on heart failure, how it drives fluid retention and shortness of breath, and why even small changes can lead to noticeable relief within days. You'll learn how to spot hidden sodium in common foods, what to eat instead, and how to build meals that support your heart without feeling restrictive or bland.We also explore simple, realistic nutrition strategies for real life, from eating well when energy is low or appetite is poor, to using flavor-forward ingredients that make low-sodium meals satisfying and sustainable. Whether you're living with heart failure, supporting a loved one, or trying to protect your heart long-term, this conversation offers practical, evidence-based guidance you can start using right away.Guest Bio:Julia Zumpano has been a registered dietitian with Preventive Cardiology and Rehabilitation at the Cleveland Clinic for 20 years. Her time in patient care is spent counseling on a cardio-protective diet, with focus on lipid, hypertension, diabetes, and weight management. She also serves as the Nutrition Media Liaison, where she manages the media requests to the outpatient Nutrition Therapy department, played an integral role in the development of the Cleveland Clinic diet app, and is the co-host of the Nutrition Essentials Podcast.“Simplify what you're consuming. Keep it very simple. Do what's with whatever is in your means, but if you are able to commit, let's say, three or four days to a low-sodium diet, you may find that you'll be able to get rid of some of that fluid you're retaining.” Question of the Day:What are some tips you use in your kitchen to make meals more flavorful without adding that extra sodium?On This Episode You Will Learn:Why sodium plays such a critical role in heart failure management, including what happens in the body when intake is too high and how it contributes to fluid buildup and worsening symptoms.How sodium affects blood pressure and heart function, why this added strain is especially dangerous for people with heart failure, and how even small reductions can lead to noticeable symptom relief.Common high-sodium foods that often go unnoticed, from packaged staples to restaurant meals, and practical tips for identifying hidden sodium on labels.What to eat for a stronger heart, highlighting staple ingredients and eating patterns that support fluid balance, reduce symptoms, and help meet nutrient needs even when appetite or energy is low.Making low-sodium eating realistic and enjoyable, with strategies to preserve flavor, honor food traditions, and build sustainable habits that support long-term heart health.Connect with Yumlish!Yumlish Website: YumlishYumlish on Instagram: @yumlish_Yumlish on Facebook: YumlishYumlish on Twitter: @yumlish_Yumlish on LinkedIn: YumlishConnect with Julia Zumpano!LinkedIn: https://www.linkedin.com/in/zumpano-julia-4757482a Nutrition Essentials Podcasts: https://www.youtube.com/playlist?list=PLMG0zKOgNqNmoVhXKP1zvIuFS5BcVXJyG

Dr. Margarita Fedorova outlines how genetic, environmental, and pathological factors interact in Parkinson's disease and what this means for patient counseling.  Show citation:  Blauwendraat C, Morris HR, Van Keuren-Jensen K, Noyce AJ, Singleton AB. The temporal order of genetic, environmental, and pathological risk factors in Parkinson's disease: paving the way to prevention. Lancet Neurol. 2025;24(11):969-975. doi:10.1016/S1474-4422(25)00271-6  Show transcript:  Dr. Margarita Federova: Welcome to Neurology Minute. My name is Margarita Fedorova, and I'm a neurology resident at the Cleveland Clinic. Today we're exploring a framework for understanding how genetic, environmental, and pathological factors interact in Parkinson's disease and what this means for how we counsel our patients. A personal view paper by Blauwendraat and colleagues, published in The Lancet Neurology in September 2025, addresses a critical question. We've identified over 100 genetic loci for Parkinson's, but how do they act? The common saying is genetics loads the gun and environment pulls the trigger, but this paper suggests the relationship may be more complex. The key tool here is alpha-synuclein seeding amplification assays or SAAs. These detect misfolded alpha-synuclein protein in cerebrospinal fluid. Over 90% of Parkinson's patients test positive for misfolded alpha-synuclein using this assay. But here's what's notable. 2% to 16% of neurologically healthy older adults also test positive with prevalence increasing with age. This means there are more asymptomatic people with detectable alpha-synuclein pathology than people with actual Parkinson's disease. Most of these asymptomatic individuals will never develop symptoms. This raises an important question. What determines who converts to a disease and who doesn't? By integrating SAA results with genetic data, researchers can examine whether genetic factors drive initial protein misfolding or whether they modulate the response to pathology triggered by environmental or random events. Preliminary data suggests polygenic risk scores don't strongly associate with SAA positivity in healthy older adults. In other words, people with high genetic risk for Parkinson's aren't necessarily more likely to have misfolded alpha-synuclein if they're healthy. This suggests most Parkinson's genetic risk factors may not be causing initial misfolding. Instead, they may be determining what happens afterward, such as whether the pathology progresses to clinical disease. LRRK2 mutations support this model. About 33% of LRRK2 related Parkinson's patients are SAA-negative compared to only 7% in sporadic disease. This means many people with LRRK2 mutations develop Parkinson's without the typical alpha-synuclein pathology. LRRK2 mutations also show varied pathology. Sometimes alpha-synuclein, sometimes tau, sometimes neither. This suggests LRRK2 may modulate responses to different initiating events rather than directly causing protein misfolding. What does this mean for us as clinicians? Asymptomatic SAA-positive individuals could represent a window for intervention. If we can understand what protects them from converting to disease or what triggers that conversion, we could enable earlier identification of at risk individuals and potentially intervene before symptoms develop. The authors call for large scale studies using SAAs in older populations, combined with genetic analysis and longitudinal follow-up. By integrating pathological biomarkers with genetic and environmental data, we can better understand the temporal sequence of events in development of Parkinson's. This approach could fundamentally change how we think about disease prevention and early intervention, potentially allowing us to identify at risk individuals before symptoms appear and develop targeted prevention strategies. That's your neurology minute for today. Keep exploring, and we'll see you next time. If you want to read more, please find the paper by Cornelis Blauwendraat et al titled The Temporal Order of Genetic, Environmental and Pathological Risk Factors in Parkinson's Disease: Paving the Way to Prevention, published online in September 2025 in Lancet Neurology.

What if playing it safe is actually keeping you from the life and relationships you truly want? Too often, fear convinces us to stay small, avoid discomfort, and stick to familiar routines, especially when it comes to our most important connections. The result? Missed opportunities for deep intimacy, vibrant trust, and authentic connection. It's a paradox: the very quest for comfort may be the greatest risk of all. In this episode, listeners are invited to challenge the idea that comfort equals happiness. Through inspiring stories and practical tools, the conversation explores how embracing courage, even in small, everyday ways, can lead to deeper, more meaningful relationships. Discover why facing fears (rather than running from them) is essential for personal growth and intimacy, and how a simple courage practice can transform both self-perception and connection with loved ones. Whether it's starting an uncomfortable conversation or supporting each other through life's uncertainties, this episode offers actionable steps to help anyone move from fear to flourishing in their relationships. Scott Simon is a thought leader, TEDx speaker, bestselling author, and founder of the Scare Your Soul movement, helping people transform their lives through small daily acts of courage. He's worked with the UN, Nestlé, Ritz Carlton, Logitech, and the Cleveland Clinic to build braver teams and more connected cultures. When he's not leading keynotes or designing transformative retreats, you'll find Scott chasing live music, journaling in strange airports, or hunting down the world's best hole-in-the-wall restaurants.   Episode Highlights 04:24 Overcoming the tendency to shrink back and building momentum through bravery and courage. 09:20 How embracing discomfort leads to growth and creativity. 16:16 How small actions outside your comfort zone can build courage and lead to transformative outcomes. 20:08 Challenging relationship norms for deeper bonds. 28:47 Unlocking authenticity through vulnerability in relationships. 32:10 Aligning courageous choices with core values in relationships. 35:30 Personal examples of standing in your truth. 39:56 Practicing self-awareness and micro acts of courage for relational growth.   Your Checklist of Actions to Take Start a daily courage practice: Each day, do one small thing that scares you or takes you out of your comfort zone, just as the guest recommends. Pause and check in with yourself: Before difficult conversations, take a moment to breathe deeply and center yourself, allowing self-awareness to guide your next steps. Reflect on your core values: Use your values as a filter when deciding which courageous actions to take in your relationships. Initiate honest conversations: If you're holding back something important, practice being the one to "go first" and share vulnerably, even if it feels risky. Name your feelings in real-time: During tough moments, state what you're experiencing physically or emotionally (e.g., "My heart is racing right now"), to foster connection and authenticity. Seek support for brave actions: Engage a partner or friend to do something courageous together, which can increase commitment and make the experience richer. Replace silence with authentic sharing: Consider what keeping quiet is truly serving, and choose to communicate openly instead of bottling things up. Practice small acts of kindness: Try courage-building social acts, like initiating a friendly conversation or buying someone a coffee, to strengthen your confidence and connectedness.   Mentioned Scare Your Soul (*Amazon Affiliate link) (book) David Schnarch (*Wikipedia link) Conscious Loving (*Amazon Affiliate link) (book) 12 Relationship Principles to Strengthen Your Love (free guide)   Connect with Scott Simon Websites: scottsimon.us | scareyoursoul.com Instagram: instagram.com/scareyoursoul Substack: scareyoursoul.substack.com

頻傳的施用包含依託咪酯等毒駕事件，導致交通部及內政部分別修正了「違反道路交通管理事件統一裁罰基準及處理細則」和「取締疑似施用毒品後駕車作業程序」，並於2025年11月20日正式上路執法。主持人 Zoe 分析，本次修法忽略精神物質代謝及其於體內實際作用的時間差。依照新修的兩細則規定，警察可對於行經臨檢站的汽機車及慢車駕駛，除酒測外也可進行唾液毒品快篩。一旦篩檢結果為陽性，即會被帶回警局驗尿。若駕駛在驗尿階段也呈陽性反應，就會違反刑法185-3 條「不安全駕駛罪」。Zoe 強調，唾液快篩是驗口水中的代謝殘留物，而不同的精神物質在體內作用的時間皆不相同。舉例來說，根據美國醫學權威單位 Cleveland Clinic 的研究，大麻可在唾液殘留24小時。這導致實際上路後，若台灣旅客於其他國家合法施用大麻製品後的24小時內在台灣駕駛汽機車，就有可能超過唾液快篩的門檻，導致即便沒有不能安全駕駛的情況，也會被認為違反不能安全駕駛罪。Zoe 也質疑唾液快篩執行的嚴謹性。雖新修「取締疑似施用毒品後駕車作業程序」有規範警察在判斷危害車輛時須符合「比例原則」，但 Zoe 認為警察在績效壓力下可能會以不同方式使駕駛同意自願搜索。駕駛若拒絕配合唾液快篩，「違反道路交通管理事件統一裁罰基準及處理細則」第19-4條規範，汽車駕駛人可處$18萬罰緩並吊銷駕照及吊扣牌照，慢車則可處 $4,800。Zoe 再次講解了「具體危險」和「抽象危險」的定義（聽眾朋友也可複習 EP123）。Zoe 也最後呼籲，她嚴格反對毒品濫用及毒駕，但她認為立法者及學者專家需要重視精神活性物質的實際作用和代謝時間這個支點，因現行規範是將「具體危險拉成抽象危險」。節目聲明：大麻

President Donald Trump has threatened to invoke the Insurrection Act to quell ongoing anti-ICE demonstrations in Minnesota in the wake of the shooting death of Renee Good by a U.S. Immigration and Customs Enforcement agent. Protests have erupted nationwide after Good's death, and there have been many in Northeast Ohio communities, including Cleveland, Akron and Kent. This week, social media has been filled locally with unverified reports of ICE activities in Cleveland. Noted immigration attorney Margaret Wong said there were reports of ICE agents in Cleveland and offered advice about people's rights should ICE agents come to their door. Cleveland Police took the extraordinary step on Wednesday to issue a statement saying it's not its job to enforce general federal immigration law. We will begin Friday's “Sound of Ideas Reporters Roundtable” with a discussion of CPD's statement and rising concerns over ICE. FirstEnergy is asking the Public Utilities Commission of Ohio to lower reliability standards for power outages, basically allowing for more outages that last longer before its determined that standards weren't met. A first hearing is scheduled for next month. The Cleveland Clinic announced yesterday that it intends to earn certification as a Level 1 trauma center at its Main Campus by 2028, its second Level 1 trauma center in the region, after Akron General. Cleveland Clinic main campus leader Dr. Scott Steele said he sees a need for this top tier of trauma care within the Clinic's own system. But Cleveland already has Level 1 trauma centers -- operated University Hospitals and also by MetroHealth, which called for the clinic to reconsider and claimed patient costs would rise as a result of the clinic's actions. An effort to repeal a new state law that makes changes to the recreational marijuana statute passed by voters and also bans intoxicating hemp suffered a setback this week. A group trying to prevent Senate Bill 56 from going into effect and allow voters to decide whether to repeal it in November had its petition summary language rejected by Attorney General Dave Yost. We've heard a lot about the Browns planned move to a new enclosed stadium in Brook Park from the Cleveland perspective. Now, we're getting a bit more insight into how the mega project could impact Brook Park. This week the Northeast Ohio Areawide Coordinating Agency or NOACA held a meeting about how the stadium could impact traffic. The Canton Hall of Fame Village has secured financing that could jump start the stalled construction on a massive indoor water park. "Game Day Bay" sits at the front of the Village property was started in 2022 but has been sitting unfinished since 2024. All this week on Ideastream Public Media you've been hearing reporting about the firefighting crisis facing Ohio. 70% of Ohio's fire departments are at least partially staffed by volunteers. Those volunteer positions are getting harder to fill as current volunteers near retirement. The reporting is a collaboration between Ideastream and The Ohio Newsroom and you'll find all the stories on our website as "Sound the Alarm". Guests: Glenn Forbes, Deputy Editor of News, Ideastream Public Media Abigail Bottar, Reporter, Ideastream Public News Karen Kasler, Statehouse News Bureau Chief, Ohio Public Radio/TV

Send us a textTingling toes. A strange electric buzz that won't let you sleep. We sat down with Dr. John Morren, Director of the Neuromuscular Center at Cleveland Clinic, to unpack what truly drives peripheral neuropathy, how to read the early signs, and which treatments actually help you function and rest again.We trace the most common causes—diabetes and the broader metabolic syndrome—while surfacing underrecognized risks like rapid weight loss, malabsorption after bariatric surgery, chemotherapy, infections, alcohol, and hidden vitamin pitfalls. B12 deficiency takes center stage as a treatable driver; we talk real thresholds, why neurologists aim above 400, and how methylmalonic acid exposes low B12 even when standard labs look “normal.”Looking ahead, we explore AI as augmented intelligence: tools that flag high-risk patients in primary care, prompt simple screening steps, and sharpen EMG and nerve conduction studies to detect nerve damage earlier. It's not man versus machine; it's smarter care through synergy, personalizing treatment and expanding access without losing the human touch.Support the show

He was a doctor, a father, and an experienced outdoorsman on a long-planned trip into Colorado's backcountry. It started off according to plan- until he continued on alone. What followed was a disappearance that sparked a massive search and left behind more questions than answers.Sources:Reddit, Edmonds and Evans Funeral and Cremation Services, Historic Fix, Cleveland Clinic, Post Independent, South Bend Tribune, Strange Outdoors, Eiseman HutSupport us on Patreon for as little as $1 a month, with benefits starting at the $3 tier!Follow us on Instagram at offthetrailspodcastFollow us on Facebook at Off the Trails PodcastIf you have your own outdoor misadventure (or adventure) story that you'd like us to include in a listener episode, send it to us at offthetrailspodcast@gmail.com  Please take a moment to rate and review our show, and a big thanks if you already have!**We do our own research and try our best to cross-reference reliable sources to present the most accurate information we can. Please reach out to us if you believe we have mispresented any information during this episode, and we will be happy to correct ourselves in a future episode.

Who should consider fertility preservation, when is the right time, and what are the risks? In this episode of BackTable OBGYN, Dr. Amy Park interviews Dr. Mindy Christianson, the section head of Reproductive Endocrinology and Infertility at the Cleveland Clinic, who shares how fertility preservation is evolving for patients planning families and those facing fertility-impacting treatments. --- SYNPOSIS Dr. Christianson discusses her journey into the field of fertility preservation, inspired by an early encounter with a breast cancer patient. The conversation covers various aspects of fertility preservation, including the preservation of eggs, embryos, ovarian and testicular tissue, and planned fertility preservation. Dr. Christianson elaborates on the protocols, patient demographics, and the evolving collaboration between oncology and reproductive endocrinology. The discussion also highlights technologies like ovarian tissue transplantation and in vitro maturation, as well as practical tips for healthcare providers on improving patient access to fertility preservation services. --- TIMESTAMPS 00:00 - Introduction03:34 - Understanding Fertility Preservation07:56 - Consultation Process for Fertility Preservation17:36 - Advancements in Egg Freezing Technology25:55 - Egg Freezing Recommendations26:34 - Collaboration Between Oncology and REI26:52 - Pediatric Oncology and Fertility Preservation28:58 - Ovarian Tissue Transplantation33:17 - Uterine Transposition Surgery40:05 - Gene Editing and Fertility Preservation43:01 - Financial and Emotional Aspects of Fertility Preservation48:02 - Practical Advice for OBGYNs51:12 - Resources and Final Thoughts --- RESOURCES Livestrong Fertilityhttps://livestrong.org/how-we-help/livestrong-fertility/ Resolve: The National Infertility Associationhttps://resolve.org/ Society for Assisted Reproductive Technologyhttps://www.sart.org/ American Society for Reproductive Medicinehttps://www.asrm.org/