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Dr. Michael Roizen returns for Part 2 of the conversation on longevity, healthspan, and the future of healthy aging. Building on the previous discussion, he dives deeper into The Great Age Reboot and the emerging science behind extending not just lifespan, but years of health, mobility, and vitality. From brain health and stress management to nutrition, movement, purpose, and the latest advances in longevity research, Dr. Roizen shares practical steps people can take today while exploring what the future of medicine may make possible tomorrow. Key Takeaways: Healthy aging is shaped by the daily choices we make long before we reach older age. Brain health benefits from movement, cognitive challenges, stress management, and meaningful engagement. Nutrition, physical activity, and healthy metabolic markers are important foundations for longevity. Purpose, friendship, and play can help support a healthier and more fulfilling life as we age. Emerging advances in gene editing, stem cell research, and other longevity therapies could reshape how we approach aging in the future. We couldn't highlight incredible stories like this without the support of our sponsor, CommunityAmerica Credit Union. Thank you for helping us promote connection, well-being, and stronger communities. If you're looking for trusted financial wellbeing resources, we invite you to connect with their team and take the next step toward greater financial confidence. About Dr. Michael Roizen: Dr. Roizen served as Cleveland Clinic's first Chief Wellness Officer from 2007 to 2019 & founding Chair of its Wellness Institute. The Clinic's Wellness Programs helped the clinic not spend over 1.250 billion dollars for its 101,000 employees & dependents over 11 years compared with national averages and help over 43.6% of participants achieve 6 normals+2 ® for health. This reduced their rate of aging and time of disability equivalent to 12.5 years over an 80 year lifespan. Dr Roizen is a recipient of an Emmy, an Elle, the Paul Rogers best medical communicator award from the National Library of Medicine, & the Bennett Family Award from GlobalWellnesSummit. He initiated & developed the RealAge concept to motivate behavior change. That started the concept that 60 could be the new 40. He believes that soon 90 will be the new 40—how you can prepare for it is described in his recently released book and app-newsletter, The Great Age Reboot and 4 YOUngevity.com Ai coaching program & free newsletter. He has authored over 195 peer reviewed scientific publications (he really is a science nerd), four New York Times #1 best sellers, 9 overall top 10 bestsellers including his initial #1 Bestseller in 5 countries, "RealAge: Are You As Young As You Can Be?", "AgeProof—Living Longer without breaking a hip or running out of money" and his book that displaced Harry Potter from #1 on Amazon for 177 days, YOU: On A Diet, The Owner's Manual for Waist Management. He served 16 years on FDA advisory committees, including chairing one for two years. His books have been translated into 44 languages and been number 1 in 5 countries in addition to the USA. He helped start 14 companies including his current Therapeutic Plasma Exchange Company, Lifespan-Edge.com, , co-invented a drug approved by the FDA, co-invented the Cloud (US Patent # 2004/0205055A1 ; his coinventor –who took it from him—was just awarded 673 million dollars from Amazon)and has a weekly podcast now in its 1268th+ week; he and Dr Oz coauthored a daily column syndicated to over 68 newspapers that translates current scientific reports into actionable steps for lay audiences. When Dr Oz declared his candidacy for public office, Dr Roizen has continued the column alone, but have recently started writing it together again, but he has restarted alone as Dr Oz is now USA's CMS Director-Administrator. He is a recipient of The United Way of Cleveland Humanitarian of the Year Award. He has won over 75 trophies in class A squash competition. His wife is a developmental pediatrician also listed in the Best Doctors in America. The Roizens have two children: Jenny, a PhD organic chemist working for the US Energy Department, and Jeffrey, an MD/PhD faculty member in pediatric endocrinology at Children's Hospital of Philadelphia. Dr. Roizen is devoted to helping people live younger. He consults with patients in Cleveland Clinic's Executive Health and Wellness Programs. He teaches them the 80% likelihood that they can be 40 at calendar age 90, and how to prepare for that. Connect with Dr. Michael Roizen at: https://4youngevity.com/ https://lifespan-edge.com/ https://michaelfroizenmd.substack.com/ Connect with Dr. Michelle and Bayleigh at: https://smallchangesbigshifts.com hello@smallchangesbigshifts.com https://www.linkedin.com/company/smallchangesbigshifts https://www.facebook.com/SmallChangesBigShifts https://www.instagram.com/smallchangesbigshiftsco https://www.youtube.com/@smallchangesbigshiftsco Thanks for listening! Thanks so much for listening to our podcast! If you enjoyed this episode and think that others could benefit from listening, please share it using the social media buttons on this page. Do you have some feedback or questions about this episode? Leave a comment in the section below! Subscribe to the podcast If you would like to get automatic updates of new podcast episodes, you can subscribe to the podcast on Apple Podcasts or Stitcher. You can also subscribe in your favorite podcast app. Leave us an Apple Podcasts review Ratings and reviews from our listeners are extremely valuable to us and greatly appreciated. They help our podcast rank higher on Apple Podcasts, which exposes our show to more awesome listeners like you. If you have a minute, please leave an honest review on Apple Podcasts.
How can dentists stay clinically sharp, adapt to digital dentistry, and maintain profitable workflows throughout their careers? In this episode, Kirk Behrendt talks with Dr. John Cranham, educator, mentor, and longtime student and faculty member of the Dawson philosophy, about the four pillars dentists need to continually develop: foundational principles, efficient and profitable workflows, ongoing education, and mentorship. They also discuss the different challenges facing emerging digital dentists and experienced clinicians transitioning into digital workflows, why technology must remain grounded in sound clinical principles, and how mentorship accelerates growth.To learn how to combine clinical fundamentals, technology, education, and feedback into a sustainable path toward excellence, listen to Episode 1101 of The Best Practices Show!Main Takeaways:Strong foundational knowledge in aesthetics, occlusion, biology, and structural integrity guides effective diagnosis and treatment planning.Efficient and profitable workflows require repeatable systems that allow the entire dental team to understand how clinical procedures should progress.Dentists need ongoing education to stay current with evolving materials, software, technology, and treatment approaches.Mentorship provides a trusted feedback loop where dentists can share their work, receive constructive guidance, and continue improving.Emerging digital dentists often understand technology quickly but need deeper clinical principles to guide how they use it.Experienced dentists often have strong clinical foundations but need support incorporating scanners, software, digital design, printing, and other technologies into their workflows.Digital dentistry allows clinicians to move faster, but foundational principles determine whether they are moving in the right direction.Episode Chapters:00:00 Intro01:19 Dr. John Cranham begins a new chapter after putting down the handpiece.02:07 The four areas dentists need to develop throughout their careers.08:27 Why mentorship requires transparency, feedback, and setting ego aside.09:00 Applying knowledge and learning through repetition and experience.12:03 The emerging digital dentist and the challenges this group faces.16:35 Why technology must be combined with sound clinical principles.21:03 The experienced dentist transitioning into digital dentistry.23:58 Why Dr. Cranham remains committed to teaching and mentoring.27:24 Why younger dentists need to actively seek mentors.31:55 The evolution from Cranham Culp Digital Dental to Dental Mastery.35:59 Goal setting, accountability, and access to mentorship.36:00 How dentists can learn more about Dental Mastery.Guest Bio:Dr. John Cranham graduated from dental school in 1988 and built a general dental practice in Chesapeake, Virginia, with a focus on aesthetic dentistry, implant dentistry, TMD, and complex restorative care. Early in his career, he completed advanced education through the Dawson Academy, the Pankey Institute, and programs associated with Kois and Spear. His Cranham Dental Seminars organization merged with the Dawson Academy in 2004, and he served as clinical director of the Dawson Academy from 2004 to 2020. He later developed Cranham Culp Digital Dental and has continued teaching comprehensive dentists how to translate traditional restorative and occlusal principles into digital workflows. He is also involved with the Pankey Institute and its educational programs.Episode Resources:Dental Mastery: dentalmastery.com1092: The Truth About Practice Ownership, DSOs, and Retirement: https://podcasts.apple.com/ph/podcast/1092-the-truth-about-practice-ownership-dsos/id1223838218?i=1000786495379More Helpful Links for a Better Practice & a Better Life:Contact Gina to learn more about ACT: gina@actdental.comThe Best Practices Show: https://www.actdental.com/podcast/Smile Source Community Hub: https://www.actdental.com/community-hubUpcoming Events & Workshops: https://www.actdental.com/events/Smile Source: https://www.smilesource.com/Subscribe on Apple Podcasts: https://podcasts.apple.comSubscribe on Spotify: https://open.spotify.com
Welcome to the NeurologyLive® Mind Moments® podcast. Tune in to hear leaders in neurology sound off on topics that impact your clinical practice.In this Mind Moments episode, Jennifer Fokas, MD, and Minali Nigam, MD, neurologists at Northwestern Medicine with specialized training in headache medicine, join the podcast to discuss current challenges and evolving strategies in the management of cluster headache. They highlighted the substantial burden of disease, particularly among patients with chronic cluster headache, and the diagnostic difficulties that arise from overlap with migraine features. They emphasized the importance of recognizing cranial autonomic symptoms as key distinguishing features, along with typical attack duration and circadian or seasonal patterns. The conversation also covered practical approaches to acute and preventive treatment, including high-flow oxygen via non-rebreather mask, subcutaneous sumatriptan, bridge therapies, and preventive options such as high-dose verapamil and, in selected cases, lithium. The physicians also review emerging and adjunctive options while noting limitations in evidence, indications, and access. They concluded by underscoring the need for clinician preparedness and tailored therapy to enable more assertive and appropriate management of cluster headache. Looking for more Headache and Migraine discussion? Check out the NeurologyLive® Headache and Migraine focus page.Episode Breakdown: 1:54 – Biggest unmet need in cluster headache 5:01 – Importance of multimodal acute management and access issues 7:39 – Neurology News Minute 10:03 – Emerging and experimental therapies 13:03– Preventive options and special situations 17:51 – Key clinical takeaway: preparation and access to therapies The stories featured in this week's Neurology News Minute, which will give you quick updates on the following developments in neurology, are further detailed here: FDA Approves Zilganersen, First Treatment for Alexander Disease FDA Priority Review Puts Satralizumab on Track as First MOGAD Drug FDA Approves Apitegromab for Spinal Muscular Atrophy Thanks for listening to the NeurologyLive® Mind Moments® podcast. To support the show, be sure to rate, review, and subscribe wherever you listen to podcasts. For more neurology news and expert-driven content, visit neurologylive.com.REFERENCE1. Burish MJ, Pearson SM, Shapiro RE, Zhang W, Schor LI. Cluster headache is one of the most intensely painful human conditions: Results from the International Cluster Headache Questionnaire. Headache. 2021;61(1):117-124. doi:10.1111/head.14021
Emerging technology is reshaping not only what engineers build, but how they build it. From software-defined and AI-powered vehicles to automation and electrification, the role of standards is changing as engineering workflows become increasingly digital, machine-readable, and AI-enabled. To learn how SAE International is navigating this next chapter, we sat down with Reuben Sarkar, CEO, to explore what's ahead for the 120-year-old organization as automotive, aerospace, commercial vehicles, and advanced air mobility increasingly converge. The conversation explores the importance of lifelong learning, the next generation of engineering talent, and how standards must evolve to keep pace in the age of AI. We'd love to hear from you. Share your comments, questions and ideas for future topics and guests to podcast@sae.org. Don't forget to take a moment to follow SAE Tomorrow Today—a podcast where we discuss emerging technology and trends in mobility with the leaders, innovators and strategists making it all happen—and give us a review on your preferred podcasting platform. Follow SAE on LinkedIn, Instagram, Facebook, X, and YouTube. Follow host Grayson Brulte on LinkedIn, X, and Instagram.
How should Australian aerospace and defence companies use patents and intellectual property to protect innovation and gain a competitive advantage? In this episode of the Space Connect Podcast, news editor Robert Dougherty is joined by Edward Genocchio, shareholder at GLMR and an experienced patent attorney and engineer with more than 30 years' experience across patents and the defence industry. The pair, attending Cicada X Tech23 in Sydney, discuss the strategic role of patents and intellectual property in Australia's aerospace and defence sector, including protecting sensitive technologies, managing trade secrets, and leveraging IP as a commercial asset. The podcast conversation includes the following topics: The role of patents in protecting innovation and generating commercial opportunities. How SMEs can balance the cost of patent protection with the strategic value of their intellectual property. The differences between patents and trade secrets, including the challenges of maintaining secrecy. How secrecy orders can protect sensitive technologies from public disclosure. The importance of early patent filing and monitoring global developments to identify competitors and inform technology development. Emerging opportunities around drones, autonomy, swarm warfare, and connected autonomous systems. Enjoy the podcast, The Space Connect team
Just a few years back, Davinia Barton wasn't leaving the house much, not for almost a year, as she worked around treatments and coped with the damage caused by her health condition, cystic fibrosis. Frequent and protracted hospital stays have been a feature throughout her life since she was very young, although recent medical advancements, and her continued ability to adapt, all paint a more positive picture today. Emerging in that picture, and becoming brighter with every round she plays, is her new sport. “I never thought for a minute I could ever even try golf, never mind play it regularly and get involved at a golf club,” Davinia says, smiling. This friendly and bright Lancastrian has gone from being a spectator, to a ‘first-go' sampler, to becoming a regular player, and more.“I think if someone with a health condition is thinking of taking up golf, they should be brave and do it. There are lots of ways to start, it's incredible.“When I'm out on the course, I feel free, all the rest is put aside and I can love the game on a beautiful golf course, with friends.”Enjoy Davinia's story here with EDGA.
This content was funded by Johnson & Johnson. This material is intended for educational and scientific exchange purposes only. It is not intended to be promotional and should not be used to make treatment decisions for any individual patient. The views expressed are those of the speaker and do not necessarily reflect those of Johnson & Johnson. Atypical EGFR mutations make up approximately 5 to 10% of EGFR-mutant NSCLC, and because some assays only report exon 19 deletions and L858R, they are easy to miss. In this short podcast, Melina Marmarelis, thoracic oncologist at the University of Pennsylvania, explains why these mutations often respond differently to EGFR TKIs and how to pick them up on NGS. She also walks through CHRYSALIS-2 Cohort C, which evaluated amivantamab plus lazertinib in treatment-naive and previously treated patients. Explore: • Why G719X and other atypical mutations alter the ATP-binding pocket differently from exon 19 del and L858R • Which assays can miss atypical mutations, and when broader NGS is needed • What CHRYSALIS-2 Cohort C evaluated, and the limitations of a single-arm phase 1/1b study • How the ASCO living guideline now addresses atypical EGFR alterations Amivantamab plus lazertinib is not approved by the US Food and Drug Administration for the treatment of atypical EGFR-mutated non-small cell lung cancer. This content includes discussion of investigational and unapproved uses. The data presented do not establish safety or efficacy for any unapproved use. Prescribers should consult the full Prescribing Information for approved indications and complete safety information. Speaker: Melina E. Marmarelis, Associate Professor of Medicine, Division of Hematology-Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA
Commonly people are talking about "peptides" to refer to a heterogeneous group of peptide medications or investigational compounds. These are increasingly promoted for injury recovery, tissue repair, performance and longevity, with BPC-157 attracting particular attention. But what evidence supports the claims made about these compounds? How should animal studies, biological mechanisms and personal anecdotes be interpreted? What is currently known about their safety? And what do recent regulatory discussions actually mean for their medical status and availability? In this episode, physician and Barbell Medicine founder Dr. Jordan Feigenbaum examines the evidence surrounding BPC-157 and other peptide medications, alongside the wider questions of risk, access and informed decision-making. Timestamps [00:13] What we want to address [04:47] Interview start [05:29] What do we mean by "peptides"? [10:32] BPC-157 evidence [16:49] Sourcing of peptides [20:19] The gray zone of pro-peptide communication [24:16] Risk sourcing vs drug effects [26:25] FDA lists and compounding [31:05] Risk tolerance and informed consent [43:02] Why did pharma abandon peptide research? [47:44] Harm reduction debate [51:48] Practical takeaways [56:20] Key Ideas segment (Premium members only) Episode Resources Go to episode page Join the Sigma newsletter for free Subscribe to Sigma Nutrition Premium Enroll in the next cohort of our Applied Nutrition Literacy course Barbell Medicine Instagram: jordan_barbellmedicine Book: Signal: What Testosterone Levels Are Telling You About Your Health Related episode: #524: Strength & Fitness Levels for Reducing Chronic Disease Risk & Promoting Health Ageing – Jordan Feigenbaum, MD Further reading: Emerging use of BPC-157 in orthopaedic sports medicine: a systematic review. 2025. Ruenzi M, Stolte M, Veljaca M, et al. Efficacy and safety of PL 14736 (BPC 157) in patients with active ulcerative colitis. Gastroenterology. 2005. Meeting abstract; full study not published.
For episode 773 of the BlockHash Podcast, host Brandon Zemp is joined by Abdul Rafay Gadit, Co-founder of ZIGChain. ZIGChain is a permissionless Layer 1 blockchain, explicitly optimized for decentralized wealth management and the tokenization of real-world assets (RWAs).
Got Questions? https://calendly.com/conrad-rodriguez/30-minute-coaching-sessionGet THE EPIC EXTENDER! CLICK HERE REDDIT PROGRESS LOGSummaryIn this episode, Dr. Alan Bauman discusses the science of hair loss, the evolution of hair restoration techniques, and how to effectively prevent and treat hair thinning. He shares insights on genetics, DHT, scalp health, and regenerative therapies, providing a comprehensive guide for men interested in maintaining or restoring their hair.Key TopicsMyths about hair transplant proceduresGenetics and DHT in hair lossScalp health and hygieneMedications like finasteride and dutasterideTopical and oral treatments including peptides and laser therapyHair transplant techniques and donor managementRisks of medical tourism in hair restorationEmerging regenerative therapies and future optionsChapters00:00 Introduction and guest introduction00:28 Common myths about hair transplant surgery02:20 Main causes of hair loss: genetics and lifestyle factors05:02 Role of DHT in male pattern hair loss07:14 Medications to lower DHT and their side effects08:20 Non-pharmaceutical treatments and regenerative therapies09:48 Risks and considerations of overseas hair procedures10:55 Donor management and the importance of early intervention12:28 The hair transplant process: from consultation to recovery16:31 Maintaining healthy hair and early detection of loss19:24 Peptides and their role in scalp health and hair growth21:26 Impact of performance-enhancing drugs on hair loss22:53 Innovations in DHT blocking and hair regeneration25:18 Using body and beard hair for transplants28:15 Typical timeline for hair restoration results31:00 Post-procedure healing and final results33:14 Emerging therapies: pigmentation and hair color rejuvenation35:04 Key takeaways: early action and expert consultation36:43 Where to find Dr. Bauman and final thoughtshttps://www.baumanmedical.comfacebook/baumanmedicalinstagram/bamanmedicallinkedinSupport the Show Click a Link BelowBelow
Emerging markets face a challenging mix of persistent inflation, potential Fed hikes, U.S. political uncertainty and geopolitical risks. Yet in this episode of Signals & Noise, David Hauner, Head of Global Emerging Markets Fixed Income Strategy at BofA Securities, explains why he remains constructive on EM carry despite a more difficult backdrop. Drawing from BofA's "Buy Back EM" outlook, Hauner outlines four key themes shaping emerging markets: Treasury market developments, a more hawkish Fed, U.S. midterm elections, and evolving EM monetary policy. He discusses why higher-yielding currencies in markets such as Brazil, Colombia, Turkey and frontier economies continue to look attractive, while remaining more cautious on EM rates and sovereign credit spreads. The episode also explores the outlook for the Chinese renminbi, risks from oil price volatility and the Iran situation, Brazil's upcoming election, and why investors should distinguish between opportunities in EM carry and risks in broader EM fixed income markets. "Bank of America" and “BofA Securities” are the marketing names for the global banking businesses and global markets businesses (which includes BofA Global Research) of Bank of America Corporation. Lending, derivatives, and other commercial banking activities are performed globally by banking affiliates of Bank of America Corporation, including Bank of America, N.A., Member FDIC. Securities, trading, research, strategic advisory, and other investment banking and markets activities are performed globally by affiliates of Bank of America Corporation, including, in the United States, BofA Securities, Inc. a registered broker-dealer and Member of FINRA and SIPC, and, in other jurisdictions, by locally registered entities. ©2026 Bank of America Corporation. All rights reserved.
'Emerging from Darkness, to the Path of a Heart Filled with Light' - Friday Dhamma videos | 11 Sep 2026. To join Ajahn Anan and the Wat Marp Jan Community online for daily chanting and meditation, you may register at https://watmarpjan.org/en/live/ for a unique link. Daily live sessions at 7.15pm - 9pm, Indochina Time (Bangkok, GMT+7).
Voices of Search // A Search Engine Optimization (SEO) & Content Marketing Podcast
AI-generated video content is evolving beyond short, generic clips. Tasia Custode of Brio Media examines the trajectory of multimodal AI video generation as tools like Google Flow mature. The discussion centers on the shift from disjointed 8-second AI clips toward storyboarded, structured scenes with narrative continuity. Custode identifies character consistency and scene continuity as the key technical thresholds separating experimental AI video output from production-ready content.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
What does it take to crack the code of protein production and why do some proteins stubbornly refuse to cooperate, despite the best efforts of scientists and engineers? Biotech's ambitions are often limited not by vision, but by the real-world bottlenecks of host cell lines and the unpredictability of post-translational modifications.Nathan Lewis, GRA Eminent Scholar at the Center for Molecular Medicine, Complex Carbohydrate Research Center, and Department of Biochemistry and Molecular Biology at the University of Georgia, has made a career out of asking impossible questions about glycosylation, cell line selection, and the hidden machinery at work inside every productive cell. He's moved beyond academic curiosity—translating discoveries into applications and even launching a company, Augment Biologics, that's taking glycoengineering from theory to practice.Topics discussed:A proximity proteomics approach to identify supporting machinery for challenging-to-express proteins like rituximab (02:36)Findings from expressing the full human secretome in CHO cells, and the correlation between host cell gene expression and protein productivity (05:00)Clarifying when host cell characteristics matter more than the protein construct itself (05:46)Emerging evidence that protein sequence and structure influence glycosylation patterns (contrary to previous dogma) (06:49)Engineering point mutations to precisely tune glycan features for improved therapeutic efficacy (09:25)The vision and activities of Augment Biologics in custom glycosylation control for drug discovery (10:32)The importance and barriers to open data sharing in bioprocessing, and thoughts on overcoming them (11:11)The shifting landscape as technology advances and the need for high-quality, annotated data (13:54)If this got you thinking about the data already sitting in your freezer, and what it would take to actually use it, start here. These four conversations dig into AI-ready data, actionable omics, hybrid-model digital twins, and the cell-engineering biology underneath it all.Episodes 263 - 264: Why AI and Automation Tools Won't Deliver Until Your Lab's Data Is Connected with David HardyEpisodes 173 - 174: Mastering Hybrid Model Digital Twins: From Lab Scale to Commercial Bioprocessing with Krist GernaeyEpisodes 169 - 170: Why Your DNA Is a Terrible Disease Predictor (And How Multi-Omics Changes Everything) with Mo JainEpisodes 77 - 78: Cell Factories Explained: How Synthetic Biology and AI Revolutionize Protein Production with Mauro TorresIf you'd rather follow the glycosylation thread, check Episodes 69 - 70: Glycoanalytics Explained with Róisín O'FlahertyConnect with Nathan Lewis:Website: www.lewislab.uga.edu LinkedIn: www.linkedin.com/in/nathanelewisFree 5-day email course, The CMC Failure Chain: the five recurring CMC mistakes that put your promising program at risk → Get it hereSupport the show
Emerging market equities have increasingly evolved into a technology and manufacturing-led asset class in the wake of a surge in AI‑related capital expenditure by the hyperscalers. Zhikai Chen, Global Head of Emerging Market Equities at BNP Paribas Asset Management, and Daniel Morris, Chief Market Strategist, discuss how emerging market equities are benefitting from both structural economic growth and the competitiveness of manufacturing and knowledge‑based sectors.For more insights, visit Viewpoint: https://viewpoint.bnpparibas-am.com/Download the Viewpoint app: https://onelink.to/tpxq34Follow us on LinkedIn: https://bnpp.lk/amHosted on Ausha. See ausha.co/privacy-policy for more information.
Every wash cycle sheds plastic. Last Monday, Andrew talked with Dr. Anja Brandon of Ocean Conservancy about microfiber pollution, and one question from that conversation stuck with him: has anyone actually fixed this yet? In this solo follow-up, Andrew traces a microfiber's actual path, from the moment agitation, heat, and detergent work it loose from a shirt, through the drain, into a wastewater treatment plant, and out the other side into biosolids, farmland, rivers, and the ocean, with a growing body of research suggesting some of it ends up in human lungs and even in the human placenta. Along the way, Andrew digs into what actually controls how much a load of laundry sheds (full loads shed less per item than half-empty ones, machine type matters, and detergent's role is murkier than expected), what the current health research says about needle-shaped fibers lodging in tissue once they're inhaled or ingested, and why a fix that already exists, a washing machine filter, keeps stalling out politically. France passed the world's first law requiring one, and it still isn't enforced. California tried and got vetoed over a cost of about $14 to $20 per machine. A federal bill is sitting in committee. Andrew also runs through the three consumer-level options available right now: the Cora Ball, a Guppyfriend mesh washing bag, and a PlanetCare retrofit filter, each with a different tradeoff between cost, maintenance, and how much they actually catch. This episode sets up tomorrow's deep dive into Ocean Conservancy's Not Safe for Wash campaign, including the capture-rate dispute between Ocean Conservancy and the appliance manufacturers' trade group that's currently stalling the push for a federal requirement. Takeaways: A single load of synthetic laundry can shed anywhere from a few hundred thousand to millions of microfibers, and agitation is the best-documented cause, though machine type, wash temperature, and detergent all play a role too. A full load of laundry sheds less per item than a half-empty one, because more fabric-on-fabric contact is actually less abrasive than items tumbling loosely with excess water. Fibers that make it past a wastewater treatment plant often end up in biosolids, which get spread on farmland as fertilizer, meaning they're relocated rather than actually removed from the environment. Emerging research has found textile-linked microplastic fibers in human lung tissue and in every human placenta tested in a 2024 study, with inhaled nylon fibers shown to disrupt developing airway cells. A washing machine filter can capture the large majority of shed microfibers for an estimated $14 to $20 added to the cost of a machine, but France's 2025 filter law remains unenforced, California vetoed its own version in 2023, and a federal bill is still in committee. Consumer-level options exist today: a Cora Ball, a Guppyfriend mesh washing bag, or a PlanetCare retrofit filter, each trading off cost, maintenance, and capture rate differently. Ocean Conservancy Website: https://oceanconservancy.org/work/plastics/ Support Independent Podcasts: https://www.speakupforblue.com/patreon Need help with your ocean non-profit, company, or project? Get the help you need with Pisces Oceans Inc.: https://www.piscesoceans.ca Connect with Speak Up For Blue Website: https://bit.ly/3fOF3Wf Instagram: https://bit.ly/3rIaJSG TikTok: https://www.tiktok.com/@speakupforblue Twitter: https://bit.ly/3rHZxpc YouTube: www.speakupforblue.com/youtube
The Cimmerians were among the first great horse nomad powers to crash into the civilizations of the ancient Near East. Emerging from the Scytho-Siberian world north of the Caucasus, they struck Urartu, devastated Phrygia and Lydia, raided deep into the Near East, and became legendary in Greek memory as one of the great barbarian terrors of antiquity.But how dangerous were they really?In this episode, we look beyond the later legends to reconstruct the Cimmerians and their Scythian cousins as actual people: their pastoral economy, horses, clothing, settlements, weapons, trade, and political organization. We examine what made mounted nomads so difficult for settled kingdoms to fight, why mobility mattered more than any supposedly unstoppable horse-archer tactic, and why the mighty Assyrian army was surprisingly well suited to defeating them.We also confront one of the strangest mysteries of Cimmerian warfare: if lightly equipped horse nomads struggled against an Assyrian battle line, how did they repeatedly overcome some of the greatest fortified cities of Anatolia?From Conan the Barbarian to Herodotus, from the Caucasus to Sardis, this is the story of the Cimmerians, the early Scythians, and the arrival of the horse nomad as a major force in Near Eastern history.Music from the show: oldeststories.net/music (or search "Oldest Stories Music")Support the show:Books: https://a.co/d/7Wn4jhSDonate: oldeststories.netPatreon / YouTube members get bonus episodes: patreon.com/JamesBleckleyNo-AI readings of ancient texts: youtube.com/@osnightreading
Emerging technology is reshaping how ships are designed, built, maintained, and sustained across the U.S. maritime industrial base. As the U.S. Navy works to modernize its fleet and increase shipbuilding production, shipbuilders are turning to digital engineering, advanced manufacturing, robotics, automation, artificial intelligence (AI), and new approaches to acquisition and workforce development to deliver more capable ships faster and more efficiently.In this episode of Emerging Tech Horizons, Dr. Arun Seraphin speaks with Admiral Rick Hunt, President of Fincantieri Marinette Marine and a member of NDIA's Board of Directors, about the emerging technologies, digital engineering practices, advanced manufacturing processes, and workforce challengesshaping the future of American shipbuilding. Drawing on his 37 years of Navy experience and leadership in industry, Hunt discusses how emerging technology, robotics, automation, and AI-enabled capabilities can strengthen the U.S. maritime industrial base and accelerate the delivery of future naval capabilities.Key Topics Include:- Why increasing production speed and designing future warships for producibility must become priorities in modern shipbuilding.- The role of robotic welding, collaborative robots, automated panel lines, and other advanced manufacturing technologies in improving efficiency, safety, quality, and production capacity.- How digital ship design, digital engineering, and model-based engineering can improve consistency, maintainability, and collaboration across shipyards and manufacturing locations.- The importance of designing ships for readiness, maintainability, sustainability, and flexibility so they can adapt to emerging technologies, evolving missions, and future capability requirements.- How commercial shipbuilding practices and dual-use emerging technologies can inform innovation across the defense industrial base.- The changing relationship between traditional shipbuilders and non-traditional companies, particularly in the rapidly evolving unmanned maritime and autonomous systems sector.- How acquisition reform, multi-year contracting, and stronger demand signals could encourage industry investment in emerging technology and advanced shipbuilding capabilities and expand shipbuilding capacity.- The challenges facing the maritime workforce, from shortages of welders and skilled tradespeople to the need for more naval architects, engineers, and workers with digital engineering and advanced technology skills. Listen to this episode of Emerging Tech Horizons to explore how emerging technology, digital engineering, robotics, and artificial intelligence are transforming the future of American shipbuilding and the U.S. maritime industrial base.NDIA Emerging Technologies Institute: https://www.ndiaeti.orgNDIA Emerging Technologies Conference: https://www.ndiatechexpo.orgBe sure to follow us on social media for updates, early access to upcoming events, inside scoops, & more:LinkedIn: https://bit.ly/4htROo0Twitter: https://bit.ly/48LHAx3Facebook: https://bit.ly/47vlht8And for more podcasts, articles, & publications covering all things emerging tech, visit: ndiaeti.org #EmergingTechnology #DigitalEngineering #Robotics #Shipbuilding #USNavy #DefenseInnovation #AdvancedManufacturing #MaritimeIndustry #DefenseIndustrialBase
In this episode, Jarvis Archer, founder of Business Reset, discusses the current state of small business debt in Australia with the ATO recently indicating that small business debts are still on the rise. Tune in to hear about: The implications of Payday Super and what effect this may have on business debts. The biggest risk factors affecting business viability at the moment. The importance of businesses seeking proactive advice early.
Walter Eckersall, heralded as college football's inaugural superstar, epitomized the duality of athletic prowess and moral ambiguity in early 20th-century sports. This discourse delves into Eckersall's meteoric rise as a quarterback at the University of Chicago, where he achieved remarkable accolades yet was ultimately expelled under dubious circumstances that marred his legacy. We uncover how the very architects of college football conspired to safeguard their national championship while Eckersall, despite his celebrated status, engaged in ethically questionable practices that included fixing games. Accompanied by insights from historians Chris Serb and Timothy Brown, we navigate the complexities of Eckersall's life, revealing the darker undercurrents that shaped his narrative and the sport itself. As we explore this multifaceted figure, we aim to present not merely a chronicle of triumph but a cautionary tale of the perils of idolization in athletics.Special thanks to the experts from our archives who helped tell this story, along with our Amazon Associate link to their amazing books, which gets you the book and provides a slight commission to Pigskin Dispatch operating costs to help the consumer, author, and the Pig Pen! Win, Win, Win!Chris Serb's book "Eckie: Walter Eckersall and the Rise of Chicago Sports" (2025)Jennifer Taylor Hall (2021) is the author of a comprehensive biography on Coach Stagg, titled "Amos Alonzo Stagg: College Football's Man in Motion."Timothy P. Brown of FootballArchaeology.com, who visits here every Tuesday, is the author of "How Football Became Football."Don't forget to check out and subscribe to the Pigskin Dispatch YouTube channel for additional content and the regular Football History Minute Shorts.Miss our football by the day of the year podcasts, well, don't, because they can still be found at the Pigskin Dispatch website. Do you want more football history? Test your Gridiron Knowledge, we feed you Daily with our new FREE activity, The Pigskin Trivia Drive.Grab a copy of our latest book, "Marooned," on the 1925 Pottsville Maroons NFL franchise saga.*OR* Grab a copy of our book on Western Pennsylvania football history, "World's Greatest Gridiron Team" on the 1903 Franklin All-StarsDrop us a line at PigskinDispatch@gmail .com and check out and subscribe to the Pigskin Dispatch YouTube channel.Contact us directly at PigskinDispatch@Gmail.comMiss our football by the day of the year podcasts, well, don't because they can still be found at the Pigskin Dispatch website. The illustrious journey of Walter Eckersall, regarded as the first iconic figure in American college football, is laden with both triumph and controversy. Emerging from the Chicago sports scene at the turn of the 20th century, Eckersall epitomized the prowess and potential of collegiate athletics. His remarkable high school tenure, marked by an impressive victory margin of 105-0 in a national championship game, ignited fervent interest from prominent coaches such as Fielding Yost of Michigan and Alonzo Stagg of the University of Chicago. Stagg's decisive intervention at a train station, where he persuaded Eckersall not to sign with rival Michigan, illustrates the fierce competition and strategic maneuverings prevalent in the early days of college football. Upon joining the University of Chicago, Eckersall's exceptional talent as a quarterback garnered accolades, leading his team to an undefeated season and a retroactively awarded national championship in 1905. However, beneath the surface of his athletic achievements lay a troubling reality of academic neglect and eventual expulsion for misconduct, which would shadow his legacy.
09/06/2026 Sunday Service - 09/06/2026 - Speaker: Rev. Dr. Leslie X Sanders - Sermon Series: - Watch Online: https://thenewcom.com/sermons/2026-09-06/09-06-2026-sunday-service/
In this first report on patronage, I introduce my Unconvention fringe to the Convention on Education, where I gather public responses and research (using AI to help collate and draft) into reports and podcast episodes; this second report focuses on school patronage. I explain that patronage is not merely historical but gives patrons major power over boards of management and school ethos, including faith formation during the school day, within a system where 88.3% of primary schools are Catholic and only 5.5% are multi-denominational. I explore how admission reform since 2018 does not resolve unequal daily experiences for children of other faiths or none, and I challenge “parental choice” as unrealistic and often prioritised over children's rights, especially in rural areas with one school. Emerging recommendations include separating admission from ethos reform, defining a minimum entitlement for every child, measuring children's experiences, testing a state-run local school model with optional after-school faith formation, and explaining patronage clearly; I end with key unanswered questions about opting out, consistency, pupil views, survey choices, and protecting minority faith rights.00:00 Convention Kickoff00:57 Podcast Format Explained02:38 Patronage Question Raised05:35 What Patronage Means07:24 How Schools Operate11:27 Parental Choice Debate15:29 Rights Over Whims17:13 Reframing The Debate21:29 AI Recommendations26:45 Unanswered Key Questions28:47 Wrap Up And Next Steps This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit simonmlewis.substack.com/subscribe
In this episode, Andrew Busch, Economist, Keynote Speaker, Futurist, Consultant, CEO, discusses how higher interest rates, changing valuations and evolving capital markets are reshaping private equity.
In this episode, Andrew Busch, Economist, Keynote Speaker, Futurist, Consultant, CEO, discusses how higher interest rates, changing valuations and evolving capital markets are reshaping private equity.
This week on the Money Makers podcast, Jonathan Davis (editor of the Investment Trusts Handbook and winner of the AIC Best Broadcast Journalist Award 2024 and 2025) is joined by Omar Negyal, lead manager of the JPMorgan Emerging Markets Dividend Income Trust (JEMI), for a discussion covering the trust's dividend-centred investment approach, the impact of the AI boom on emerging market technology stocks, positioning across commodities, financials, China and India, and the trust's competitive standing. This discussion was recorded on Thu 03 Sep 2026. Jonathan is now writing market and other comments on Substack (jdinvestor.substack.com), and for those of you who follow Money Makers on social media, two new channels are now available - TikTok (@moneymakers_its) and Bluesky (@money-makers.co). Do give us a follow! *** OUT NOW: The 2026 Investment Trusts Handbook *** Available to order from Harriman House: https://harriman-house.com/authors/jonathan-davis/the-investment-trusts-handbook-2026/9781804094358 The Investment Trusts Handbook 2026 is the ninth edition of the highly regarded annual handbook for anyone interested in investment trusts – often referred to as the City's best-kept secret, or the connoisseur's choice among investment funds. It is expertly edited by well-known author and professional investor Jonathan Davis, founder and editor of the Money Makers newsletter and podcast. It is available through bookshops and extensively online. The next edition of the Handbook, an independent educational publication, is now in preparation. With articles by 30 different authors, including analysts, fund managers and investment writers, plus more than 80 pages of detailed data and analysis, the latest edition is an indispensable companion for anyone looking to invest in the investment trust sector. *** Timestamps 0:00:37 - Introduction 0:01:07 - The JEMI mandate and difference with JMGI 0:07:10 - Increasing the dividend level 0:10:17 - Emerging markets performance and AI stocks 0:16:05 - AI bubble concerns? 0:20:40 - A short break 0:21:25 - Deviating from the benchmark 0:23:31 - Trump decisions and commodities 0:27:08 - Exposure to financials 0:30:46 - China and India 0:34:21 - The competitive landscape 0:37:18 - Close If you enjoy the weekly podcast, why not also try the Money Makers Circle? This is a membership scheme that offers listeners to the podcast an opportunity, in return for a modest monthly or annual subscription, to receive additional premium content every week, including interviews, performance data, links to third party research, market/portfolio reviews and regular comments from the editor. A subscription costs £12 a month or £120 for one year, with a two week free trial available for new subscribers. This week, as well as the usual features, the Circle features a profile of HarbourVest Global Private Equity (HVPE). Future profiles include Ruffer Investment Company (RICA) and Baillie Gifford UK Growth (BGUK). Our weekly subscriber email includes a comprehensive summary of all the latest news plus the week's biggest share price, NAV and discount movements. Subscribe and you will never miss any important developments from the sector. For more information please visit https://money-makers.co/circle. Membership helps to cover the cost of producing the weekly investment trust podcast, which will continue to be free for the foreseeable future. We are very grateful for your continued support and the enthusiastic response to our 350 podcasts since we launched in 2020. You can find more information, including relevant disclosures, at www.money-makers.co. Please note that this podcast is provided for educational purposes only and nothing you hear should be considered as investment advice. Our podcasts are also available on the Association of Investment Companies website, www.theaic.co.uk. Produced by Ben Gamblin - www.bgprofessional.co.uk
Peptides are everywhere right now — BPC-157, the Wolverine Stack, GLP-1s, NAD+, MOTS-C, GHK-Cu. You've probably heard at least one of them by now. So what are they actually, what does the science support, and where does the hype get ahead of the evidence?In this conversation, Emylee + Pieter Vodden are joined by Coach Vincent to unpack the rapidly evolving world of peptide therapy — without trying to convince you to be pro- or anti-peptide.We talk about: → What peptides are and how they signal the body → The Core 4: energy, recovery, metabolism + hormone health → Why peptide medicine isn't actually new → Why human research is still limited for many popular compounds → BPC-157 + TB-500 and the "Wolverine Stack" → GLP-1s + the rapidly changing metabolic peptide space → Why sourcing matters — grey-market products vs. medically supervised care → Bloodwork, cycling + physician oversight → Where peptides may fit alongside training, nutrition, sleep + recoveryThe biggest takeaway? Emerging ≠ proven. But emerging ≠ worthless either.Our position at Pharos is simple: build the foundation first, stay curious, stay informed, and don't confuse hype with evidence.This conversation is educational and is not medical advice. Decisions about medications, compounded products or peptide therapies should be made with an appropriately licensed healthcare professional.Interested in peptide therapy through Pharos? Link in bio to connect with a licensed physician through our partner network.Interested in getting started with peptides through Pharos? We're launching in Palm Springs first with full medical guidance, doctor consultation and 503A compliant sourcing.Click the link for our bio-performance survey.
In this podcast episode, BJ Rimel, MD, and Elizabeth Lee, MD, discuss the scientific rationale for targeting CDH6 in ovarian cancer and the emerging role of CDH6-directed antibody–drug conjugates (ADCs) in platinum-resistant disease, including:CDH6 biology, expression patterns, and its potential as a therapeutic target in ovarian cancerEarly-phase efficacy data with investigational CDH6-directed ADCs, including raludotatug deruxtecan (R-DXd) and CUSP06, and an ongoing phase III trial of R-DXdSafety considerations with CDH6-directed ADCs, including cytopenias, gastrointestinal toxicities, fatigue, and interstitial lung disease/pneumonitisConsiderations for sequencing ADCs, including the potential impact of target expression, payload class, and mechanisms of resistancePresenters:BJ Rimel, MDDivision Chief, Gynecologic OncologyProfessor, Department of OB/GYNUniversity of WashingtonClinical Director of Gynecologic OncologyFred Hutchinson Cancer CenterSeattle, WashingtonElizabeth Lee, MDDivision of Gynecologic OncologyCenter for Cancer Therapeutic InnovationDepartment of Medical OncologyDana-Farber Cancer InstituteBoston, MassachusettsLink to full program: https://bit.ly/3SqCAZ6Get access to all of our new podcasts by subscribing to the Decera Clinical Education Podcast on Apple Podcasts, YouTube Music, or Spotify. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
MacroVoices Erik Townsend & Patrick Ceresna welcome, Carly Anderson. They discuss the coming “nuclear renaissance” driven by small modular reactors and mass manufacturing and how deep‑tech venture investing and industrial robotics can accelerate this energy transition. https://bit.ly/3Up1SaC Website: https://timescale.vc Substack: https://timescalevc.substack.com/ (coming soon) ✅Sign up for a FREE 14-day trial at Big Picture Trading: https://secure.bigpicturetrading.com/membership/signup/fOY4YJYX
In this episode of the Pain and Performance Podcast, Dr. Derrick Hines sits down with Dr. Jerry Mixon to explore the science of longevity and what it really takes to extend not just lifespan, but healthspan.They discuss the role of hormones, exercise, mitochondrial health, and biological age testing, along with emerging research on senescent cells and the future of anti-aging medicine. The conversation also covers practical strategies for maintaining muscle, improving metabolic health, and building habits that support healthy aging over the long term.In This Episode-- The difference between lifespan and healthspan-- How hormones influence healthy aging-- Why muscle and exercise are essential for longevity-- Measuring biological age and key health markers-- The science behind senescent cells and aging-- Emerging therapies shaping the future of longevity medicineLinks: DERRICKInstagram:https://www.instagram.com/derrickbhines/Youtube:https://www.youtube.com/@DrDerrickJERRYWebsite: https://www.longevitymedicalclinic.com/Facebook: https://www.facebook.com/LongevityMedicalClinic/
In this episode of Resiliency Radio with Dr. Jill, Dr. Jill Carnahan sits down with researcher and collaboration architect Nikki Schultek to explore an often-overlooked contributor to chronic disease: persistent infections and their impact on inflammation, immunity, and the brain. Drawing from her own experience with severe chronic illness, Lyme disease, Chlamydia pneumoniae, and autoimmunity, Nikki shares how her personal health journey led her into research and a mission to connect scientific disciplines that too often operate in isolation. Together, they explore the emerging concept of the pathobiome, the potential infectious drivers of Alzheimer's and other neurodegenerative diseases, the challenges of diagnosing persistent infections, and why understanding the body as an interconnected ecosystem could transform the future of chronic illness research and treatment.
Emerging technology is rapidly transforming unmanned systems, aviation, and defense operations. As autonomous technologies evolve from prototypes into systems that can be produced and deployed at scale, industry is rethinking how these platforms are designed, manufactured, and integrated into next-generation defense technology and mission capabilities.In this episode of Emerging Tech Horizons, Dr. Arun Seraphin speaks with Paul Fermo, President of Robinson Unmanned, a recently introduced business unit of Robinson Helicopter Company and previously known as Ascent AeroSystems, about the rapidly evolving world of unmanned aviation and autonomous drone technology. Drawing on his experience as a naval aviator, requirements developer, and industry leader, Fermo discusses how autonomous systems are evolving the relationship between manned and unmanned platforms and what it will take to deliver reliable defense capabilities at scale.Key topics include:How smaller unmanned aircraft and drone systems are accelerating the pace of emerging technology development and creating new demands for agile manufacturing and production.The role of commercial and dual-use platforms in driving defense technology innovation, expanding applications, and creating opportunities to achieve greater production scale.How drones and unmanned aviation systems can support missions ranging from surveillance, search and rescue, and medical transport to contested logistics and casualty evacuation.The importance of modular, reliable, and upgradable unmanned platforms that allow operators to integrate new hardware and software as defense technologies evolve.How the Drone Dominance Program and advanced market commitments are helping push industry from emerging technology innovation toward industrialization, greater production capacity, and scalable drone capabilities.The convergence of artificial intelligence, machine learning, autonomy, advanced materials, communications, and data exploitation in next-generation unmanned aviation and defense technology.The future of integrated, collaborative drone and autonomous systems in which multiple platforms work together and AI-enabled technologies help operators make faster, more informed decisions.Why multi-year purchasing signals could help industry make the long-term investments needed to build scalable unmanned aviation, drone, and defense capabilities.NDIA Emerging Technologies Institute: https://www.ndiaeti.orgNDIA Emerging Technologies Conference: https://www.ndiatechexpo.orgBe sure to follow us on social media for updates, early access to upcoming events, inside scoops, & more:LinkedIn: https://bit.ly/4htROo0Twitter: https://bit.ly/48LHAx3Facebook: https://bit.ly/47vlht8And for more podcasts, articles, & publications covering all things emerging tech, visit: ndiaeti.org#RobinsonUnmanned #sUAS #UASEcosystem #DroneIndustrialBase #UnmannedSystems #AutonomousSystems #DefenseTechnology #EmergingTechnology
Caption: 1521 PERSIATONIGHT CONTENTS THE JOHN BATCHELOR SHOW 8-31-2026Tehran Under Siege: Sanctions, War Fatigue, and the Credibility Crisis of the UNEdmund Fitton-Brown details the bleak economic reality for citizens in Tehran living under severe economic sanctions and a low-intensity conflict. Ordinary residents are reduced to driving for ride-sharing apps like Snapp and begging for food due to skyrocketing prices of staple goods like yogurt. While the regime's elite remain insulated, sanctions have severely strained the general population without driving systemic behavior changes. Furthermore, the discussion examines the declining global credibility of the United Nations. The organization has abandoned its neutrality by focusing excessively on targeting Israel and prioritizing humanitarian relief, which frequently ends up diverted to empower oppressive regimes. (1)Demographic Doom: How the One-Child Legacy and Youth Cynicism Threaten China's FuturePiero Tozzi explores China's severe demographic crisis resulting from the legacy of the totalitarian one-child policy enacted in 1979 and officially lifted in 2015. Despite transitioning to a three-child policy, fertility rates continue to plummet due to youth disillusionment. The gender imbalance has catalyzed widespread female trafficking from neighboring countries, while a high proportion of single-child soldiers in the military creates unique domestic vulnerabilities in conflict scenarios. Young Chinese citizens are increasingly opting out of intense economic exploitation through passive resistance movements like "laying flat" and "letting it rot," directly challenging propaganda regarding national rejuvenation. (2)The Domestic Surge: AI Infrastructure, Aerospace Recovery, and US Manufacturing RenaissanceAlan Tonelson highlights the significant manufacturing revival currently taking place in the United States, driven by key sectors like aerospace and artificial intelligence infrastructure. Boeing's resolution of safety and production issues has revitalized aerospace, while a massive buildout of AI data centers has boosted demand for semiconductors, steel, and electronic equipment. Although trade tensions with Canada persist, the US-Mexico-Canada Agreement protects most trade, rendering short-term disruptions minimal. Furthermore, while widespread local protests against data centers have emerged across various states, they have not yet slowed down the overall rapid pace of construction. (3)Middle East Realignment: Iranian Devaluation, Turkish Expansion, and Mediterranean Defense PartnershipsMalcolm Hoenlein covers shifting geopolitical and economic dynamics across the Middle East. Inside Iran, severe inflation, food shortages, and medicine price hikes are suffocating the middle class, prompting harsher internal crackdowns by the regime. Meanwhile, Omani channel shipping flows have partially improved following US-led mine sweeping efforts. In Syria, Turkey is pursuing a quiet military takeover, a move contested by Israel. Additionally, Saudi Arabia is utilizing pipelines to bypass shipping threats, and Finland has joined other nations in defunding the corrupt Palestinian refugee agency UNRWA. Finally, Greece and Israel have solidified a historic $3.5 billion multi-level defense agreement. (4)Cult of Rebellion: Understanding the Resilient and Hostile Ideology of the HouthisEdmund Fitton-Brown chronicles the history, structure, and ideological motivations of the Houthi movement in Yemen. Emerging in the mid-1990s as a Zaydi revivalist cult modeled after Lebanese Hezbollah, the group adopted a highly hostile five-part slogan ("the scream") emphasizing anti-American, anti-Semitic, and anti-Israel vitriol. Over decades of conflict, they waged multiple rebellions against former dictator Ali Abdullah Saleh before forming a tactical alliance with him to seize power. Known as relentless fighters who are always up for a battle, the Houthis harbor expansive territorial ambitions in southern Saudi Arabia, aiming to control the holy sites of Mecca and Medina. (5)Tehran in Limbo: Evaluating Sanctions, Bureaucratic Alienation, and Paths to Regime ChangeJanatyn Sayeh addresses the psychological state of "no war, no peace" in Tehran a year after the September 2025 conflict. The population faces deep war fatigue, compounded by blockades and new sanctions. While sanctions alone cannot topple the regime, they successfully alienate key socio-economic groups. Specifically, lower-level administrative bureaucrats and ideologues are losing their financial incentives and faith in the regime's competence. True systemic change will not happen overnight, but dragging out the process and bringing civil unrest into urban streets could break pro-regime morale and dismantle the kleptocratic elite's hold on power. (6)Deterrence and Covert Diplomacy: Analyzing CIA Trip to Moscow and the North Korean AllianceJohn Hardie analyzes CIA Director John Ratcliffe's unexpected visit to Moscow. Speculation suggests the trip aimed to deter Russian sabotage against NATO, push for a diplomatic settlement in Ukraine, and pressure Moscow to limit support for Iran. Although Russian leader Vladimir Putin remains convinced of victory and resistant to compromises, maintaining deterrence remains critical. Simultaneously, military intelligence reports that North Korea has supplied dozens of short-range ballistic missiles to Russia for use in Ukraine, with thousands of combat troops potentially deployed, further complicating the global security landscape. (7)A Shift in Rules: IDF's Aggressive Gaza Targeting, Tunnel Demolition, and West Bank Air PowerSamuel Ben-Ur highlights a shift in Israeli military operations. Following a ceasefire, the IDF returned to pre-agreement rules by striking an active Hamas militant at a Gaza bakery. The military has destroyed roughly half of Gaza's tunnels, with operations continuing on the Hamas-controlled side. Additionally, Israel executed a rare West Bank airstrike to eliminate Kais Betawi, a high-value financial and military operative, signaling strength ahead of upcoming elections. Finally, the discussion outlines the total exclusion of the heavily compromised UNRWA from future Gaza recovery efforts, noting that the United States and Israel will sideline the agency entirely. (8)Higher Education in Crisis: Rising Debt, STEM Brain Drain, and Political PolarizationTom Katsouleas critiques the declining public trust and degrees in American higher education despite high spending. Driven by cost, value, and inclusion issues, students face massive debts that delay major life milestones like marriage and housing. Public universities have increased tuition to compensate for shrinking state budgets, while investing in luxury facilities and high-end services. In graduate education, US research programs depend heavily on international students—primarily from China—for STEM fields. However, rising immigration hostility and aggressive geopolitical competition are reversing this brain drain, while perceived progressive bias further polarizes public trust. (9)The Strategic Vanguard: Hezbollah's Regional Reach, Ceasefire Probing, and Lebanese Shia PoliticsDavid Daoud outlines the strategic dynamics of Hezbollah in Lebanon. Hezbollah is currently launching pinprick probing attacks to test Israel's rules of engagement under ceasefire constraints and US pressure. Within Lebanesepolitics, the Shia community remains structured around a symbiotic relationship between the nationalist Amal movement and Hezbollah, preventing any independent Shia opposition from gaining ground. Beyond Lebanon, Hezbollah acts as the tip of the spear for Iranian expansionism, training regional proxies in rocket, tunnel, and propaganda warfare. This veteran, transnational expertise makes Hezbollah an indispensable regional asset that Iran would find impossible to replace. (10)The Silent Drip: Structural Remedies for America's $40 Trillion Debt CrisisThomas Savidge addresses the economic implications of the United States crossing the $40 trillion national debt threshold, fueled by pandemic spending and mandatory entitlements. This massive debt competes with private capital, driving up consumer borrowing rates and depressing real wages through inflation. To halt this slow economic drip, Savidge proposes a "fiscal constitution." This includes strong constitutional amendments, Colorado-style spending caps tied to population growth and inflation, a silent-approval budget commission to enact spending cuts, and strict regulatory limits on the scope of government authority to prevent accounting tricks. (11)
CAPTION: 1926 YEMENEdmund Fitton-Brown chronicles the history, structure, and ideological motivations of the Houthi movement in Yemen. Emerging in the mid-1990s as a Zaydi revivalist cult modeled after Lebanese Hezbollah, the group adopted a highly hostile five-part slogan ("the scream") emphasizing anti-American, anti-Semitic, and anti-Israel vitriol. Over decades of conflict, they waged multiple rebellions against former dictator Ali Abdullah Saleh before forming a tactical alliance with him to seize power. Known as relentless fighters who are always up for a battle, the Houthis harbor expansive territorial ambitions in southern Saudi Arabia, aiming to control the holy sites of Mecca and Medina. (5)
Emerging young star Davina Thorne has only been wrestling for about a year and a half, but “The Head Diva” is already making her name around Chicagoland and even around the country. Thorne joins Windy City Slam for the first time to discuss training at the Freelance Wrestling Academy, working at places such as Freelance Wrestling and AAW Pro, how BloodStone Wrestling brought her and her boyfriend, fellow wrestler, Anakin Murphy, together, Deathmatch wrestling, her parents being wrestling fans, working against nationally-known talent such as Nyla Rose and Serena Deeb, how the Divas Revolution helped inspire her and more. Plus, Mike recaps premium live events from AEW, NXT and AAA and takes a spin around the local scene with news from POWW Entertainment and ICW Milwaukee and previews lineups for Freelance Wrestling, Rocket Pro Wrestling and Wrestle League. Mike Pankow is a 25-year-plus professional journalist and wrestling superfan who covers local Chicagoland wrestling and national promotions like AEW and WWE. If there is something going on in Chicago, Mike knows about it. Enjoy “Wrestling, Chicago-Style” on The Broadcast Basement On-Demand Radio Network! Music by Jason Shaw on Audionautix.com. Get your local wrestling fix every Tuesday everywhere podcasts can be found and always at WindyCitySlam.com!
Neurologist David Perlmutter MD says the beta-amyloid theory of Alzheimer's is wrong — and the real culprit is your brain's own immune cells. In this episode of Health Longevity Secrets, Robert Lufkin MD sits down with the #1 New York Times bestselling author to unpack his new book Brain Defenders: how diet, blood sugar, and metabolic health flip the brain's microglia from protective to destructive, why anti-amyloid drugs offer "trivial" benefit, and which biomarkers actually predict your brain's future.Chapters:00:00 — Introduction01:38 — Why He Left Mainstream Neurology to Prevent Brain Decline05:24 — Building the World's Largest Integrative Neurology Practice06:55 — The Common Pathway From Metabolism to Brain Degeneration08:25 — Why the Beta-Amyloid Theory of Alzheimer's Is Wrong09:11 — What Are Microglia? The Brain's Immune Cells (M1 vs M2)12:13 — From Brain "Glue" to Master Regulators of Your Synapses16:00 — How Body Inflammation and Cytokines Reach the Brain18:15 — Leaky Gut, the Microbiome, and Brain Degeneration19:46 — Ultra-Processed Foods Raise Alzheimer's Risk Up to 270%25:02 — Synaptic Pruning: The Link Between Autism, ADHD and Alzheimer's29:36 — Why Diabetics Recover Worse From Head Trauma31:51 — Anti-Amyloid Drugs: "Trivial" Benefit, Serious Harm35:37 — The Biomarkers to Track: Fasting Glucose, Insulin, A1C40:09 — On the Horizon: Mitochondrial Therapies and Microglial Transplants45:26 — Glyphosate, Air Pollution and 40Hz Light Therapy47:00 — Brain Defenders Releases August 18 — Final TakeawaysKey takeaways:Alzheimer's is increasingly understood as a "synaptopathy" — a disease of lost synapses driven by the brain's own immune cells (microglia), not simply beta-amyloid plaque.Microglia shift from supportive (M2) to destructive (M1) in response to metabolic signals: high blood sugar, insulin resistance, elevated blood pressure, excess body fat, and inflammation.A long-term cohort found each daily serving of ultra-processed food raised Alzheimer's risk ~13%, with 10+ servings/day linked to a 2.7-fold (270%) increase.A Cochrane review of anti-amyloid antibodies found "trivial" cognitive benefit alongside meaningful harm, including brain swelling and microbleeds (ARIA).The most actionable brain biomarkers are cheap and accessible: fasting glucose, fasting insulin, A1c, waist circumference, and a continuous glucose monitor — aim for optimal, not just "normal."Emerging frontiers target the mitochondria inside microglia — metformin, CoQ10, urolithin A, exercise, fasting, ketones, and 40Hz gamma light therapy.Studies & sources:Weinstein et al., J Prev Alzheimers Dis — ultra-processed food and Alzheimer's riskCochrane Review (2026) — anti-amyloid monoclonal antibodies for Alzheimer'sIaccarino, Tsai et al. (Tsai Lab, MIT) — 40Hz gamma light and microgliaDr. Lufkin's book "Lies I Taught in Medical School": https://robertlufkinmd.com/lies/⭐ Enjoying the show? Please leave a 5-star review on Apple Podcasts — it takes 30 seconds and helps more people discover the science of health and longevity. Thank you!New episodes every other Tuesday. Subscribe so you don't miss one.Continue this conversation on Substack: https://robertlufkinmd.substack.comLies I Taught In Medical School — Free sample chapter: https://www.robertlufkinmd.com/lies/Web: https://www.robertlufkinmd.comYouTube: https://www.youtube.com/robertlufkinmdX: https://x.com/robertlufkinmdInstagram: https://www.instagram.com/robertlufkinmd/TikTok: https://www.tiktok.com/@robertlufkinLinkedIn: https://www.linkedin.com/in/robertlufkinmd/
BUFFALO, NY – September 1, 2026 – A new #review was published in Volume 17 of Oncotarget on August 28, 2026, titled “Emerging biomedical imaging applications of tumor-derived extracellular vesicles for premetastatic niche detection: Biological rationale, engineering strategies, and translational challenges.” The review was led by first author Omkar Dhaygude, who is affiliated with Johns Hopkins University. Corresponding authors Franck Housseau and John Michel are affiliated with Johns Hopkins University, with Housseau also affiliated with the Cancer Research Center of Lille in France. Extracellular vesicles (EVs) are membrane-enclosed particles released by cells that transport proteins, lipids, nucleic acids, metabolites, and other molecular cargo. In cancer, tumor-derived extracellular vesicles (TEVs) can influence the tumor microenvironment and distant tissues by promoting processes such as angiogenesis, extracellular matrix remodeling, inflammatory signaling, immune evasion, and stromal reprogramming. Of particular interest is the role of TEVs in establishing premetastatic niches—biological environments in distant organs that become permissive to metastatic cells before overt tumors are detectable. TEVs can carry organ-specific molecular signals, and their surface molecules may influence which tissues they reach. For example, previous experimental research has linked the integrins α6β4 and α6β1 with lung tropism, providing a biological rationale for using TEVs to direct imaging probes toward metastasis-prone organs. This possibility could address an important limitation of conventional cancer imaging. Computed tomography and other anatomical methods are designed primarily to detect established structural lesions, whereas premetastatic niches are characterized by earlier molecular and microenvironmental alterations. The authors therefore examine whether TEV-associated imaging could provide information about metastatic conditioning before conventional imaging can identify overt metastatic lesions. Full press release - https://www.oncotarget.com/news/pr/tumor-derived-extracellular-vesicles-show-promise-for-earlier-detection-of-metastatic-risk/ DOI - https://doi.org/10.18632/oncotarget.28916 Correspondence to - Franck Housseau - fhousse1@jhmi.edu, and John Michel - jmiche14@jhmi.edu Abstract video - https://www.youtube.com/watch?v=0zygNvj4_YY Sign up for free Altmetric alerts about this article - https://oncotarget.altmetric.com/details/email_updates?id=10.18632%2Foncotarget.28916 Subscribe for free publication alerts from Oncotarget - https://www.oncotarget.com/subscribe/ Keywords - cancer, lung metastases, cancer imaging, theranostic, premetastatic niches, extra-cellular vesicles To learn more about Oncotarget, please visit https://www.oncotarget.com and connect with us: Facebook - https://www.facebook.com/Oncotarget/ X - https://twitter.com/oncotarget Instagram - https://www.instagram.com/oncotargetjrnl/ YouTube - https://www.youtube.com/@OncotargetJournal LinkedIn - https://www.linkedin.com/company/oncotarget Pinterest - https://www.pinterest.com/oncotarget/ Reddit - https://www.reddit.com/user/Oncotarget/ Spotify - https://open.spotify.com/show/0gRwT6BqYWJzxzmjPJwtVh MEDIA@IMPACTJOURNALS.COM
Rob Gerberry, Adjunct Faculty, University of Notre Dame, speaks with Michael Peregrine about emerging health care workforce issues that require the Board's attention and how a Board's human capital/human resources committee can best exercise oversight of these issues. They discuss how these committees can “retool” to address emerging workforce issues, issues related to employee burnout, why retraining employees is a governance issue, the concept of the “degradation of the quality of work,” and concerns around the impact of artificial intelligence on employee loyalty and hiring practices.Watch this episode: https://www.youtube.com/watch?v=nFY-yc9v5xsEssential Legal Updates, Now in AudioAHLA's popular Health Law Daily email newsletter is now a daily podcast, exclusively for AHLA Comprehensive members. Get all your health law news from the major media outlets on this podcast! To subscribe and add this private podcast feed to your podcast app, go to americanhealthlaw.org/dailypodcast.Stay At the Forefront of Health Legal EducationLearn more about AHLA and the educational resources available to the health law community at https://www.americanhealthlaw.org/.
Tokenization continues to evolve, with builders bringing stocks, ETFs, and other financial instruments on-chain to expand access to capital markets and enable new forms of trading and collateralization. Ian De Bode of Ondo Finance joins our hosts to explore the rise of tokenized securities, their role across markets, the infrastructure required for always-on trading, and how regulation may influence the future of investing and market access. Episode Topics: [00:00] Intro [03:52] Emerging trends in tokenization [08:52] Ondo perps and tokenizing collateral [20:11] About the Ondo network and related models [29:16] Regulation and the future of on-chain investing Stay connected with us beyond the podcast by following FCAT on, Instagram, LinkedIn, and X, where we share additional insights and updates on all things emerging tech. Whether you're crypto-curious or have a crypto foundation, Fidelity may have your next career opportunity. EXPLORE NOW. Please remember: this podcast is solely for informational and educational purposes and is not investment, tax, legal or insurance advice. Digital assets are speculative and highly volatile and you should conduct thorough research before you invest. To learn more, visit: FCATalyst.com FMR LLC. © 2026 FMR LLC. All rights reserved. Chapters (00:00:00) - Intro(00:03:52) - Emerging trends in tokenization(00:08:52) - Ondo perps and tokenizing collateral(00:20:11) - About the Ondo network and related models(00:29:16) - Regulation and the future of on-chain investing
Dr. Cassandra Evans joins Vanessa to break down the science of protein, body recomposition, fat loss, muscle preservation, genetics, caffeine, and women's iron health. BACK TO SCHOOL SALE! For a limited time, save 40% sitewide at ketogenicgirl.com with code BACKTOSCHOOL40, including the Protein-Sparing Modified Fasting Library, ToneLUX Red Light Therapy Collection, and Tone Breath Ketone Analyzer. Australia, New Zealand & Southeast Asia: Save 75% on available ToneLUX and Tone products during the warehouse moving sale with code WAREHOUSE75, while supplies last. They discuss how much protein may be optimal during body recomposition and fat loss, including research showing that higher-protein diets can help preserve lean mass, improve satiety, and in some cases even support muscle gain while losing body fat. Cassandra also shares fascinating protein-overfeeding research suggesting that increasing calories from protein may affect body composition very differently than overfeeding on fat or carbohydrates. They break down the myth that high-protein diets are harmful to bone health, including research in resistance-trained women, and explore the FTO "obesity gene," how it may influence hunger and food intake, and why exercise appears to reduce some of the differences associated with genetic risk. Try my favorite new electrolytes Cure Hydration! Head to curehydration.com/VANESSA and use code VANESSA to save 20% on your order.
Drs. Berger and Denny review recent stroke conference data on Factor XIa inhibitors and evolving strategies for secondary stroke prevention. They highlight image-guided extended‑window tenecteplase to broaden reperfusion eligibility.
In today's episode of The Quiz, we're testing your knowledge on everything from executive White House architecture to viral internet dance trends and everyday adhesive inventions. Can you answer these? Executive Offices: The primary office space of the Commander-in-Chief in the West Wing is named after its distinct geometric layout. Do you know what shape gives this room its iconic name? Dance Craze: Emerging from Atlanta's hip-hop culture in 2015, a signature move where dancers lean into their bent elbow swept across social media and sports celebrations. Can you name this viral trend? Autumn Foliage: As autumn approaches, tree leaves transform into brilliant shades of yellow and orange due to specific natural plant pigments. What are these organic compounds called? Play. Share. Listen, with Fox News Senior Correspondent & ‘Searching For Heroes‘ podcast host, Benjamin Hall. Learn more about your ad choices. Visit podcastchoices.com/adchoices
In this episode, Maria Varmazis and Dave Bittner from N2K Cyberwire get back together to discuss the evolution of advanced persistent threats (APTs), threat actor landscape, attribution changes, and the future of cyber espionage over the past decade. Join Dave and Maria as they explore how geopolitical factors, organizational professionalism, and emerging technologies like AI are shaping cybersecurity threats. Together, they talk about: The shift in attribution practices over the last 10 years. The role of nation states and organized crime in cyber threats. The impact of AI and emerging technologies on cyber warfare. The challenges of naming and shaming threat groups. The professionalization and organizational evolution of APT groups.
Not Conformed But Transformed - Rev. Dr. Dennis Edwards Aug/30/2026 Sunday Service - Speaker: Sermons - Sermon Series: Rooted - Watch Online: https://thenewcom.com/sermons/2026-08-30/not-conformed-but-transformed/
Emerging From the Light My Near Death Experience - Short Version
When her husband died in 1908, 50-year-old Rose Knox inherited America's largest manufacturer of unflavored gelatin. For a respectable woman then, running a national factory was unthinkable, so for six years she ran the Knox Gelatin company invisibly. Rachel Greenfield, a Harvard MBA searching for trailblazers before the "firsts" of the 1960s, found Rose's papers hidden in an attic. But she didn't just find a forgotten CEO, but the inventor of modern influencer marketing, decades before Betty Crocker. It's a story of marketing, reinvention at 50, and the woman who proved you could check the icebox at night and run the boardroom by day.Get your copy of Rose Knox by rachel Greenfield As an Amazon Associate, Now I've Heard Everything may earn a commission from qualifying purchases.Chapters:02:39 - The Evolving American Consumer 05:35 - Running a Business in Secret 07:29 - Emerging into the Public Eye 10:21 - From Bone-Boiling to Instant Gelatin 13:36 - Knox vs. Jell-O: A Marketing Masterclass 16:26 - Pragmatism Over Politics 18:28 - The Legacy of Rose KnoxGuest Informationrachel GreenfieldWebsiteSocial:Facebook2003 interview with Dexter Scott King1994 interview with Dolly PartonFor more intriguing and engaging interviews each week, subscribe now on:Spotify Apple Podcasts YouTube
If your face has gotten redder, more reactive and burning in your in your 40s or 50s (or your rosacea seems much worse), perimenopause rosacea could be an important piece of the puzzle. Emerging research suggests shifting hormone levels can trigger and also influence rosacea symptoms, including acne bumps, reactive skin, flushing, burning, stinging + increased skin sensitivity.Before you JUST blame this all on hormones, hormone-triggered rosacea must be looked at from a few different perspectives. In this episode, I'm diving into fascinating research connecting hormones, your gut microbiome + rosacea severity, plus what to consider when the usual rosacea fixes aren't giving you sustainable results.⭐️Mentioned in This Episode:- See all the references
What if some of the most disabling symptoms in EDS, HSD, POTS, MCAS, ME/CFS, and long COVID are being driven by something we still struggle to see on standard testing? In this episode of Bendy Bodies, Dr. Linda Bluestein is joined by guest co-host Dr. Ina Stephens, Associate Director of the UVA Health EDS and Hypermobility Disorder Center, along with Brain Inflammation Collaborative co-founder Christy Jagdfeld and neuroscientist Dr. Megan Fitzgerald. Together, they explore the rapidly evolving science of brain inflammation, including what it actually means, how it differs from conditions like encephalitis or brain edema, and why it may matter in complex multisystem illness. The conversation dives into microglial activation, mast cell involvement in the central nervous system, and the challenge of detecting subtle neuroinflammation in living patients. The guests also discuss emerging research tools, including ultra-high-field MRI, PET ligands, and blood-based extracellular vesicles, that may eventually give clinicians a clearer window into what is happening inside the brain. The group also takes a closer look at the Brain Inflammation Collaborative's Unhide platform, which is collecting real-world, patient-reported data across more than 30 overlapping chronic conditions, including EDS, POTS, MCAS, ME/CFS, and long COVID. Early findings raise important questions about quality of life, symptom burden, the limitations of the Beighton score, and why pediatric research may be especially important. The episode closes with practical implications, including why pacing matters when exercise can worsen symptoms rather than improve them, and what patients and clinicians should watch as this field moves forward. Takeaways “Brain inflammation” can involve subtle processes such as microglial activation and mast cell signaling that may not appear on routine MRI or CT scans. Emerging tools such as ultra-high-field MRI, PET imaging, and blood-based extracellular vesicles may eventually help researchers detect and track neuroinflammation in living patients. The Unhide platform has collected real-world data from thousands of participants with overlapping chronic conditions, offering a new way to study symptom burden and quality of life outside traditional clinical trials. The Beighton score may not reflect functional severity or symptom burden, highlighting the need for better ways to assess hypermobility over time. Pediatric research is urgently needed to understand how these conditions develop and whether earlier recognition could change long-term outcomes. Want more of the Brain Inflammation Collaborative? https://www.unhidenow.org/ https://www.braininflammation.org/ Want to learn more about the UVA EDS Center? For Appointments and Questions: RUVAEDSCenter@uvahealth.org UVA EDS: https://www.uvahealth.com/healthy-practice/advancing-care-through-ehlers-danlos-clinic UVA EDS FAQ: https://www.uvahealth.com/support/eds/faq UVA Pediatric Integrative Medicine: https://childrens.uvahealth.com/specialties/integrative-health Want more Dr. Linda Bluestein, MD? Website: https://www.hypermobilitymd.com/ YouTube: https://www.youtube.com/@bendybodiespodcast Instagram: https://www.instagram.com/hypermobilitymd/ Facebook: https://www.facebook.com/BendyBodiesPodcast X: https://twitter.com/BluesteinLinda LinkedIn: https://www.linkedin.com/in/hypermobilitymd/ Newsletter: https://hypermobilitymd.substack.com/ Shop my Amazon store https://www.amazon.com/shop/hypermobilitymd Dr. Bluestein's Recommended Herbs, Supplements and Care Necessities: https://us.fullscript.com/welcome/hypermobilitymd/store-start Thank YOU so much for tuning in. We hope you found this episode informative, inspiring, useful, validating, and enjoyable. Join us on the next episode for YOUR time to level up your knowledge about hypermobility disorders and the people who have them. Join YOUR Bendy Bodies community at https://www.bendybodiespodcast.com/. YOUR bendy body is our highest priority! Learn more about Human Content at http://www.human-content.com Podcast Advertising/Business Inquiries: sales@human-content.com Part of the Human Content Podcast Network Go to AirDoctorPro.com and use promo code BENDY_ to get UP TO $300 off today! FTC: This video is not sponsored. Links are commissionable, meaning I may earn commission from purchases made through links Chapters: 00:00 Beighton Score Debate00:28 Meet the Guests02:54 Why BIC Was Founded07:22 Defining Brain Inflammation09:44 Biomarkers and Imaging Advances18:12 Unhide Platform and Real World Data25:55 Comorbidities and Survey Cadence31:40 Survey Fatigue Solutions32:49 Tools Beyond Beighton34:16 Research Priorities Wish List35:41 Biomarkers EVs Immune Profiling38:37 Pediatric Focus Early Signs46:34 Building Pediatric Platform53:07 Hacks Resources And Wrap Up Learn more about your ad choices. Visit megaphone.fm/adchoices
In "Scale or Fail: Navigating Trade Volatility for Emerging Brands", Joe Lynch speaks with President and CEO of the Americas region of GEODIS, Laura Ritchey, about how emerging brands can navigate trade volatility, manage inventory, and build scalable, resilient supply chains. About Laura Ritchey Laura Ritchey joined GEODIS in July 2025 as President and Chief Executive Officer (CEO) of the Americas region. Laura is responsible for overseeing the region's freight forwarding, contract logistics and transportation business units along with engineering and technology, IT, ProVenture (U.S.-based subsidiary of GEODIS focusing on industrial real estate) and Material Handling Resources (one of the country's leading material handling distributors owned by GEODIS). In total, Laura oversees GEODIS Americas' expansive operations including nearly 20,000 employees and more than 230 sites across eight countries. Laura brings over 30 years of experience to GEODIS, with 15 focused on supply chain management in both retail and third-party logistics. Laura began her career in finance before transitioning to supply chain operations, including sourcing, distribution and strategic transformation. Prior to her current role, Laura was most recently CEO at Radial, Inc., a leader in e-commerce fulfillment solutions, where she drove revenue growth and profitability through operational excellence. At Radial, she led the North American P&L for a $1.4B e-commerce logistics division, responsible for relationships with over 170 clients across four service lines. Before joining Radial, she held leadership positions at L Brands, FullBeauty Brands and Centric Brands. Laura is on the Dean's Advisory Council at Fisher College of Business at The Ohio State University and is an active board member of the Federal Reserve Bank of Atlanta's Nashville Branch. Additionally, she is actively involved with C200 whose mission is to inspire, educate, support and advance current and future women leaders. Laura earned her J.D., MBA and bachelor's degree from The Ohio State University. Additionally, Laura is accredited as a certified public accountant and admitted to the bar in Ohio. About GEODIS GEODIS is a leading global logistics provider acknowledged for its expertise across all aspects of the supply chain. As a growth partner to its clients, GEODIS specializes in four lines of business: Global Freight Forwarding, Global Contract Logistics, Distribution & Express Transport, and European Road Network. The Group operates a global network spanning nearly 170 countries and 48,000 employees. In 2025, GEODIS generated €10.6 billion in revenue. GEODIS is a company owned by SNCF group. Key Takeaways: Scale or Fail: Navigating Trade Volatility for Emerging Brands Beware the "10K Order Trap" During Rapid Growth: Scaling operations from 1,000 to 10,000 monthly orders often breaks a business before demand stalls. Emerging brands must build strong foundational supply chain building blocks early—such as maintaining clean master data (accurate dimensions and weights) and choosing a 3PL capable of global growth—to avoid costly operational failures when reaching inflection points. Adopt a Hybrid Inventory Strategy to Balance JIT and JIC: Shifting strictly between "Just in Time" (JIT) and "Just in Case" (JIC) risks either stockouts or trapped working capital. A balanced, hybrid approach—keeping adequate stock of fast-moving core basics while tightly controlling slow-moving seasonal items—helps protect cash flow without sacrificing availability. Re-evaluate the "Amazon Effect" and Recommerce to Protect Margins: High-speed, free shipping creates an illusion of necessity that drives up last-mile costs. Brands should focus on order delivery certainty over pure speed while implementing circular economy strategies (recommerce) to rehabilitate and resell returned apparel, which often recovers up to 95% of inventory value. Mitigate Sourcing Risks Beyond Single-Factory Bets: Diversifying supply chains requires going all the way back to raw material inputs rather than simply relocating assembly plants. Navigating evolving global tariffs requires nearshoring flexibility, dual-sourcing critical SKUs, and re-orchestrating supply chain flows across regional hubs. Understand True Landed Costs to Avoid Margin Shock: Delegating freight forwarding and customs clearance entirely to overseas manufacturers often leads to hidden markups and supply chain delays. Leveraging an end-to-end global provider with licensed customs brokerage capabilities ensures clear visibility into total landed costs and regulatory compliance. Leverage Global Scale with Curated, End-to-End Execution: Supported by a global network spanning nearly 170 countries, over 48,000 employees, and €10.6 billion (USD $12.35 billion) in revenue (2025), GEODIS provides emerging and established brands with an agile, end-to-end "launchpad for global growth" across contract logistics, freight forwarding, and transportation. Avoid the "Set It and Forget It" Supply Chain Mindset: Ongoing volatility, regulatory shifts, and geopolitical friction require continuous evaluation of supply chain networks. Taking a cautious, practical approach to emerging technologies like AI (for labor forecasting and route planning) ensures operational stability while safeguarding proprietary data. Learn More About Scale or Fail: Navigating Trade Volatility for Emerging Brands Laura Ritchey | Linkedin GEODIS | Linkedin GEODIS The Logistics of Logistics Podcast If you enjoy the podcast, please leave a positive review, subscribe, and share it with your friends and colleagues. The Logistics of Logistics Podcast: Google, Apple, Castbox, Spotify, Stitcher, PlayerFM, Tunein, Podbean, Owltail, Libsyn, Overcast Check out The Logistics of Logistics on Youtube
Menopause Mastery | 6 New Menopause Studies Every Woman Should Know About | Ep. 293 solocast with Dr. Betty Murray
The superstars came to play on Tuesday (2:30). ... Time to add George Klassen (5:35)? ... Braxton Ashcraft looks to be back (11:45). ... It was a big night for the Brewers offense (15:00). ... News (21:03): Edwin Diaz is going back on the IL. ... Jo Adell had a monster night (34:37). ... Kyle Leahy and Tyler Mahle continued to pitch well (45:48). ... Let's fire up the WORRY-O-METER (51:35)! ... We wrap up with leftovers, bullpens and streamers (1:03:47).Subscribe to our YouTube channel: youtube.com/FantasyBaseballTodaySign up for the newsletter at https://www.cbssports.com/newsletters