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Everyone wants to live a long life, but no one wants to get old. Just over 15 years ago, cardiologist Dr Eric Topol went looking for genetic reasons why some people are able age into their 80's without the usual chronic diseases like diabetes or cardiovascular issues. Dr Topol the founder and director of the Scripps Research Institute in San Diego says genetics are not destiny and it's never too late to start taking steps to delay or even prevent disease.
In this conversation, Michael Shermer and Dr. Eric Topol discuss the realties of aging, with particular focus on the role of AI in enhancing patient care and disease prevention, the importance of lifestyle factors, and the limitations of genetic testing in predicting health outcomes. Topol also explains the dangers of ultra-processed foods, their link to inflammation, and the role of GLP-1 drugs in promoting healthier eating habits. The conversation also covers diet, particularly the differences between chicken and red meat, and the significance of sleep for overall health. Plus, consumption of microplastics, cholesterol management and statins, the critical role of social connections in maintaining mental and physical health, and the future of personalized medicine in cancer prevention. Eric Topol is a cardiologist and one of the top ten most cited researchers in medicine, known for his groundbreaking studies on AI in medicine, genomics, and digitized clinical trials. Topol is also the executive vice president and a professor of molecular medicine at Scripps Research, the largest nonprofit biomedical institute in the United States. He was named one of the Top 100 most influential people in health in 2024 by Time. His new book is Super Agers.
This week, Kristen and I go full sci-fi (but, like, the real kind) with the one and only Dr. Eric Topol—cardiologist, author, and guy who's been yelling for years that the way we do medicine is… less than ideal. We talk about how AI could transform healthcare, whether doctors are finally ready to embrace empathy, and why the average hospital still runs on fax machines and vibes. Oh—and don't worry, I made sure to ask him if AI is going to come for my job. (Spoiler: probably.) It's a hopeful, sometimes uncomfortable, but deeply fascinating look at what medicine could be—if we don't screw it up. Takeaways: Why Dr. Topol believes the biggest failure in medicine isn't technology—it's the loss of empathy. How large language models (like ChatGPT) are already reshaping diagnostics and documentation. Why we should worry less about AI replacing doctors—and more about bad doctors using AI. The shocking inefficiencies still plaguing hospitals (hello, fax machines). What med schools might look like in the near future—and why humility should be part of the curriculum. — Want more Dr. Eric Topol? X: @EricTopol To Get Tickets to Wife & Death: You can visit Glaucomflecken.com/live We want to hear YOUR stories (and medical puns)! Shoot us an email and say hi! knockknockhi@human-content.com Can't get enough of us? Shucks. You can support the show on Patreon for early episode access, exclusive bonus shows, livestream hangouts, and much more! – http://www.patreon.com/glaucomflecken Also, be sure to check out the newsletter: https://glaucomflecken.com/glauc-to-me/ If you are interested in buying a book from one of our guests, check them all out here: https://www.amazon.com/shop/dr.glaucomflecken If you want more information on models I use: Anatomy Warehouse provides for the best, crafting custom anatomical products, medical simulation kits and presentation models that create a lasting educational impact. For more information go to Anatomy Warehouse DOT com. Link: https://anatomywarehouse.com/?aff=14 Plus for 15% off use code: Glaucomflecken15 -- A friendly reminder from the G's and Tarsus: If you want to learn more about Demodex Blepharitis, making an appointment with your eye doctor for an eyelid exam can help you know for sure. Visit http://www.EyelidCheck.com for more information. Produced by Human Content Learn more about your ad choices. Visit megaphone.fm/adchoices
Fredrik talks to Matt Topol about Arrow and how the Arrow ecosystem is evolving. Arrow is an open source, columnar in-memory data format designed for efficient data processing and analytics - which means passing data between things without needing to transform it, and ideally even without needing to copy it. What makes the ecosystem grow, and why is it very cool to have Arrow on the GPU? What is the connection between Arrow, machine learning, and Hugging face? Matt emphasizes the value of open standards, even as they work with or within more closed systems they can help open things up, and help bring about more modular solutions so that developers can focus on doing their core area really well. This episode can be seen as a follow-up to episode 567, where Matt first joined to discuss everything Arrow. Recorded during Øredev 2024. Thank you Cloudnet for sponsoring our VPS! Comments, questions or tips? We a re @kodsnack, @tobiashieta, @oferlundand @bjoreman on Twitter, have a page on Facebook and can be emailed at info@kodsnack.se if you want to write longer. We read everything we receive. If you enjoy Kodsnack we would love a review in iTunes! You can also support the podcast by buying us a coffee (or two!) through Ko-fi. Links Matt Matt's Øredev 2023 talks: State of the Apache Arrow ecosystem: How your project can leverage Arrow! and Leveraging Apache Arrow for ML workflows Previous episodes with Matt Øredev 2024 Matt's Øredev 2024 talks - on Arrow ADBC and Composable and modular data systems ADBC - Arrow database connectivity Arrow Snowflake Snowflake drivers for ADBC Bigquery The Bigquery driver Microsoft Fabric Duckdb Postgres SQLite Arrow flight - RPC framework for services based on Arrow data Arrow flight SQL Microsoft Power BI Velox Apache datafusion Query planning Substrait - query IR Polaris Libcudf Nvidia RAPIDS Pytorch Tensorflow Arrow device interface DLPack - in-memory tensor structure Tensors Nanoarrow Voltron data - where Matt used to work. He's now at Columnar Theseus GPU compute engine The composable data management system manifesto Support us on Ko-fi! Matt's book - In-memory analytics with Apache Arrow Spark Spark connect RPC UDFs Photon Datafusion Apache Cassandra ODBC JDBC R - programming language for statistical computing Hugging face Ray Stringview - “German-style strings” Scaling up with R and Arrow - the book on using Arrow with R Titles It's gotten a lot bigger The bones of it are in the repo (Powered by ADBC) Individual compute components Feed it substrate Where the ecosystem is going Arrow on the GPU The data stays on the GPU A forced copy Leverage that device interface Without forcing the copy Shy of that last mile Turtles all the way down The guy who said yes German-style strings
Fredrik talks to Matt Topol about Arrow and how the Arrow ecosystem is evolving. Arrow is an open source, columnar in-memory data format designed for efficient data processing and analytics - which means passing data between things without needing to transform it, and ideally even without needing to copy it. What makes the ecosystem grow, and why is it very cool to have Arrow on the GPU? What is the connection between Arrow, machine learning, and Hugging face? Matt emphasizes the value of open standards, even as they work with or within more closed systems they can help open things up, and help bring about more modular solutions so that developers can focus on doing their core area really well. This episode can be seen as a follow-up to episode 567, where Matt first joined to discuss everything Arrow. Recorded during Øredev 2024. Thank you Cloudnet for sponsoring our VPS! Comments, questions or tips? We a re @kodsnack, @tobiashieta, @oferlund and @bjoreman on Twitter, have a page on Facebook and can be emailed at info@kodsnack.se if you want to write longer. We read everything we receive. If you enjoy Kodsnack we would love a review in iTunes! You can also support the podcast by buying us a coffee (or two!) through Ko-fi. Links Matt Matt’s Øredev 2023 talks: State of the Apache Arrow ecosystem: How your project can leverage Arrow! and Leveraging Apache Arrow for ML workflows Previous episodes with Matt Øredev 2024 Matt’s Øredev 2024 talks - on Arrow ADBC and Composable and modular data systems ADBC - Arrow database connectivity Arrow Snowflake Snowflake drivers for ADBC Bigquery The Bigquery driver Microsoft Fabric Duckdb Postgres SQLite Arrow flight - RPC framework for services based on Arrow data Arrow flight SQL Microsoft Power BI Velox Apache datafusion Query planning Substrait - query IR Polaris Libcudf Nvidia RAPIDS Pytorch Tensorflow Arrow device interface DLPack - in-memory tensor structure Tensors Nanoarrow Voltron data - where Matt used to work. He’s now at Columnar Theseus GPU compute engine The composable data management system manifesto Support us on Ko-fi! Matt’s book - In-memory analytics with Apache Arrow Spark Spark connect RPC UDFs Photon Datafusion Apache Cassandra ODBC JDBC R - programming language for statistical computing Hugging face Ray Stringview - “German-style strings” Scaling up with R and Arrow - the book on using Arrow with R Titles It’s gotten a lot bigger The bones of it are in the repo (Powered by ADBC) Individual compute components Feed it substrate Where the ecosystem is going Arrow on the GPU The data stays on the GPU A forced copy Leverage that device interface Without forcing the copy Shy of that last mile Turtles all the way down The guy who said yes German-style strings
Imagine a future where the aging process can be delayed and more people live active, healthy and disease-free lives well into their 90s. That reality may be sooner than you think, according to Dr. Eric Topol, author of the new book “Super Agers: An Evidence-Based Approach to Longevity.” Ali Rogin speaks with Topol about the rapidly advancing science of healthy aging. PBS News is supported by - https://www.pbs.org/newshour/about/funders
Imagine a future where the aging process can be delayed and more people live active, healthy and disease-free lives well into their 90s. That reality may be sooner than you think, according to Dr. Eric Topol, author of the new book “Super Agers: An Evidence-Based Approach to Longevity.” Ali Rogin speaks with Topol about the rapidly advancing science of healthy aging. PBS News is supported by - https://www.pbs.org/newshour/about/funders
Imagine a future where the aging process can be delayed and more people live active, healthy and disease-free lives well into their 90s. That reality may be sooner than you think, according to Dr. Eric Topol, author of the new book “Super Agers: An Evidence-Based Approach to Longevity.” Ali Rogin speaks with Topol about the rapidly advancing science of healthy aging. PBS News is supported by - https://www.pbs.org/newshour/about/funders
People are becoming increasingly more interested in living longer. Health, wellness, dieting, and fitness are more and more prominent on social media, and health monitoring technology are becoming increasingly popular. Cardiologist Dr Eric Topol has been researching longevity for decades, and is considered to be one of the top five voices on the subject. He's just released his latest book, ‘Super Agers', a detailed guide to living a longer, healthier life. Topol told Mike Hosking it's not necessarily about living longer, but rather extending the years someone lives with intact health. He says living to 90 and being perfectly health throughout ought to be more important than trying to live to 110 and having many years of dementia, or profound frailty, or poor quality of life. Although there are revolutions happening in regards to anti-inflammatory and hormonal medications, Topol says it's never going to be as simple as a pill. Things like lifestyle factors, environmental pollution, microplastics, and forever chemicals also need to be controlled, he explains. Listen to the full interview for a detailed explanation of health, longevity, and the new developments in the medical sector. LISTEN ABOVE See omnystudio.com/listener for privacy information.
Speciální série podcastu Dobrovský & Šídlo s hostem Janem HartlemEpizoda třetí: Jak Topolánek s Paroubkem přivedli své strany na vrchol. A pak z něj spadli
Tony chats with Graham Topol and Michael Topol, Co-Founders and Co-CEOs at MGT Insurance, they are the first Neo Insurer, a modern commercial insurance carrier which they built from the ground up to support small businesses and the agents that support them. A super interesting conversation that you cannot miss!Graham Topol: https://www.linkedin.com/in/graham-topol-645b5451/Michael Topol: https://www.linkedin.com/in/michael-topol-74710b99/MGT Insurance: https://www.mgtinsurance.com/Video Version: https://youtu.be/_cJv2osE4-w
When it comes to medical science, there's never been a better time to be alive than now… other than maybe a few months ago before the new Trump administration. Americans today are living longer than ever before, and that's owed in no small part to the National Institutes of Health—a government organization that has been responsible for some of the most significant biomedical advancements in the history of healthcare. Unfortunately, the Trump administration just virtually annihilated the NIH, and sentient gob of clay and anti-vax charlatan RFK Jr. is now in charge of the future of American health. To figure how how to navigate this insane dichotomy of medical potential and squandered medical possibility, Adam speaks with Dr. Eric Topol, a cardiologist and scientist, and director of the Scripps Research Translational Institute. Dr. Topol's book, Super Agers: An Evidence-Based Approach to Longevity, explores the cutting edge advancements in living longer, healthier lives—advancements which are now in jeopardy. Find Dr. Topol's book at factuallypod.com/books--SUPPORT THE SHOW ON PATREON: https://www.patreon.com/adamconoverSEE ADAM ON TOUR: https://www.adamconover.net/tourdates/SUBSCRIBE to and RATE Factually! on:» Apple Podcasts: https://podcasts.apple.com/us/podcast/factually-with-adam-conover/id1463460577» Spotify: https://open.spotify.com/show/0fK8WJw4ffMc2NWydBlDyJAbout Headgum: Headgum is an LA & NY-based podcast network creating premium podcasts with the funniest, most engaging voices in comedy to achieve one goal: Making our audience and ourselves laugh. Listen to our shows at https://www.headgum.com.» SUBSCRIBE to Headgum: https://www.youtube.com/c/HeadGum?sub_confirmation=1» FOLLOW us on Twitter: http://twitter.com/headgum» FOLLOW us on Instagram: https://instagram.com/headgum/» FOLLOW us on TikTok: https://www.tiktok.com/@headgum» Advertise on Factually! via Gumball.fmSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Gil and Eric discuss Eric's book, Super Agers, and the inspiration behind it: a 98-year-old patient who exemplified healthy aging. They explore the five dimensions of healthspan optimization: lifestyle, omics, the immune system, and the role of data and AI in personalized medicine. Eric highlights how AI can analyze multi-layered data to provide personalized recommendations for preventing age-related diseases.The conversation also explores the importance of exercise, sleep, and social connection for healthy aging, as well as the risks associated with high-dose statins. Eric emphasizes the need for a shift towards preventative care, using data and AI to identify and address individual risks. He stresses the power of lifestyle changes, rather than supplements, in improving long-term health outcomes. Guest-at-a-Glance
Tereza Šídlová byla výjimečný host. Nejen proto, že se známe dlouho a že jsem ji kdysi učil na Fakultě sociálních věd. Výjimečné ale bylo to, že jsme natáčeli v den, kdy promovala a tedy po delší přestávce své studium úspěšně ukončila. Ale samozřejmě jsme se bavili taky o spoustě dalších věcí.Témata?Například: Měl ruský vliv podíl na pádu Topolánkovy vlády v roce 2009? Tereza Šídlová ve své diplomové práci zkoumá kauzu amerického radaru v Brdech jako možný příklad rané hybridní války. To, co se tehdy zdálo být domácí politickou fraškou, může podle její analýzy představovat sofistikovanou ruskou operaci.Samozřejmě to nebylo naše jediné téma: zeptal jsem se třeba na to, jak vzpomíná na svou práci na izraelské ambasádě, a zajímalo mě, jestli někdy litovala, že si vzala jméno svého manžela novináře.Řeč přišla na kampaň "Dobré ráno Česko", která má najít pozitivní příběh České republiky. Tedy na kampaň, na kterou se já dívám se skepsí a možná až cynismem, a Tereza naopak optimisticky.Takže budete svědky toho, jak se mě snaží přesvědčit, že byť jako stát možná nejsme zcela výjimeční, tak národní branding si každopádně zasloužíme. Protože - a to je zajímavá myšlenka - národní branding není jen marketing, ale může být důležitý i pro národní bezpečnost.Nehledě na to, že Tereza soudí, že by Česku obecně asi prospělo méně cyniků a více optimistů.Ono to souvisí i s tím, jak se na budoucnost dívá ona: po přechodu z novinařiny do státní služby, po boji s vážnou nemocí a po dokončení vysoké školy je stále optimistická. Věří, že svět za deset let bude lepší místo.Přeju si, aby to tak bylo, a vám přeju příjemný poslech!
Dvaadvacetiletá Rozárie Haškovcová se dostala do veřejného povědomí, když v živém vysílání České televize klidně, ale razantně upozornila expremiéra Mirka Topolánka, aby ji neoslovoval povýšenecky „Rozárko“. My jsme ji pozvali do Generačního konfliktu nejen proto, aby nám řekla, co schytávají mladé ženy, které se pokoušejí promlouvat do veřejných záležitostí, od starších chlapů. Ale hlavně, aby vysvětlila, jak to má vlastně mladá generace s ochranou životního prostředí. Řeč je o tom, kdo to je vlastně greenfluencer/ka, o klimatické úzkosti, osobní odpovědnosti, létání letadlem a o tom, co je podle ní pro ochranu klimatu skutečně podstatné. Každý si asi poslechne Rozárii Haškovcovou, která vystupuje na sociálních sítích pod přezdívkou „shluk buněk“, z jiných důvodů. Ale všechny stojí za to.
What if we could delay--or even prevent--Alzheimer's, cancer, and heart disease? What if much of what you know about aging is wrong? Listen as cardiologist and author Eric Topol of the Scripps Research Institute talks about his new book Super Agers with EconTalk's Russ Roberts. They discuss why your genes matter less than you think, how your immune system can help prevent cancer and Alzheimer's, and why a simple shingles vaccine could reduce the risk of dementia. From the surprising anti-inflammatory powers of Ozempic to the critical importance of deep sleep for brain detoxification, Topol shares insights that can extend your healthy lifespan.
Jeho bratr, frontman skupiny Psí vojáci Filip Topol, by letos oslavil šedesátiny. „Umřel moc mladý, jeho tvorba mohla pokračovat,“ říká ve Vizitce a připomíná, že Filip začal velmi brzo vystupovat, roky hrál a neměl rodinný život. „Bohéma pro něj byla setrvalý stav a když se k tomu přidá alkohol, je to sebezničující.“ Kdy si připadal jako dědeček Jimiho Hendrixe? A s jakou myšlenkou napsal text, který proslavila Monika Načeva? Ptá se Ondřej Cihlář.Všechny díly podcastu Vizitka můžete pohodlně poslouchat v mobilní aplikaci mujRozhlas pro Android a iOS nebo na webu mujRozhlas.cz.
Jeho bratr, frontman skupiny Psí vojáci Filip Topol, by letos oslavil šedesátiny. „Umřel moc mladý, jeho tvorba mohla pokračovat,“ říká ve Vizitce a připomíná, že Filip začal velmi brzo vystupovat, roky hrál a neměl rodinný život. „Bohéma pro něj byla setrvalý stav a když se k tomu přidá alkohol, je to sebezničující.“ Kdy si připadal jako dědeček Jimiho Hendrixe? A s jakou myšlenkou napsal text, který proslavila Monika Načeva? Ptá se Ondřej Cihlář.
Americans are unusually overweight and chronically ill compared to similarly rich countries. This episode presents a grand, unified theory for why that's the case. Our food environment has become significantly more calorie-rich and industrialized in the past few decades, sending our obesity rates soaring, our visceral fat levels rising, and our chronic inflammation surging. The result is an astonishing rise in chronic illness in America. That's the bad news. The good news is that GLP-1 drugs, like Ozempic and Zepbound, seem to be astonishingly successful at reversing many of these trends. This episode blends two interviews with Dr. David Kessler and Dr. Eric Topol. Kessler was the commissioner of the Food and Drug Administration under the Bush and Clinton administrations, from 1990 to 1997. He helped lead Operation Warp Speed in its final months. He is the author of the book 'Diet, Drugs, and Dopamine.' Topol is a cardiologist and the founder and director of the Scripps Research Translational Institute. He is the author of the book 'Super Agers.' If you have questions, observations, or ideas for future episodes, email us at PlainEnglish@Spotify.com. Host: Derek Thompson Guests: Dr. David Kessler and Dr. Eric Topol Producer: Devon Baroldi Learn more about your ad choices. Visit podcastchoices.com/adchoices
„Nebe je rozbouřeno, hvězdy prší, lučištníci zmateně pobíhají, kosti nebeského lva se třesou,“ to jsou verše starých Egypťanů, které v jedné ze svých esejí citoval Josef Topol, protože byl přesvědčený, že báseň a mýtus mají společné předky: instinkt a magickou moc a dodával, že na samém počátku nejsou od sebe k rozeznání.
„Nebe je rozbouřeno, hvězdy prší, lučištníci zmateně pobíhají, kosti nebeského lva se třesou,“ to jsou verše starých Egypťanů, které v jedné ze svých esejí citoval Josef Topol, protože byl přesvědčený, že báseň a mýtus mají společné předky: instinkt a magickou moc a dodával, že na samém počátku nejsou od sebe k rozeznání.Všechny díly podcastu Názory a argumenty můžete pohodlně poslouchat v mobilní aplikaci mujRozhlas pro Android a iOS nebo na webu mujRozhlas.cz.
Svět nám ruskou invazí na Ukrajinu ujel pod nohama a máme tady tu samou strašnou nenávist a krutou válku, která si nezadá s týráním lidí za druhé světové války, je přesvědčený spisovatel a dramaturg programu Knihovny Václava Havla Jáchym Topol. „Patřím ke generaci 90. let, kdy brilantnější mozky, než je ten můj, věřily, že Rusko touží po demokracii. Já jsem iluze nikdy neměl,“ vzpomíná pro Český rozhlas Plus.Všechny díly podcastu Osobnost Plus můžete pohodlně poslouchat v mobilní aplikaci mujRozhlas pro Android a iOS nebo na webu mujRozhlas.cz.
Cardiologist, scientist and bestselling author Dr. Eric Topol's new book "Super Agers" distills decades of research on how to make us healthier for longer. Topol says that humanity is on the cusp of developing treatments to help tame cancer, dementia and other chronic diseases… just as political forces in the U.S. are shutting down that research.
Pětidílná hudebně-dokumentární série Petra Ference přibližuje tvorbu Psích vojáků, nechybí alter ego Kilián Nedory, rodinná anamnéza a otisk jeho bytosti ve filmu Žiletky.
Pětidílná hudebně-dokumentární série Petra Ference přibližuje tvorbu Psích vojáků, nechybí alter ego Kilián Nedory, rodinná anamnéza a otisk jeho bytosti ve filmu Žiletky.
Pětidílná hudebně-dokumentární série Petra Ference přibližuje tvorbu Psích vojáků, nechybí alter ego Kilián Nedory, rodinná anamnéza a otisk jeho bytosti ve filmu Žiletky.
Pětidílná hudebně-dokumentární série Petra Ference přibližuje tvorbu Psích vojáků, nechybí alter ego Kilián Nedory, rodinná anamnéza a otisk jeho bytosti ve filmu Žiletky.
Pětidílná hudebně-dokumentární série Petra Ference přibližuje tvorbu Psích vojáků, nechybí alter ego Kilián Nedory, rodinná anamnéza ani otisk jeho bytosti ve filmu Žiletky.
Filip Topol, frontman skupiny Psí vojáci, básník, hudbymilec a sebedestruktivní umělec života, by se 12. června dožil šedesáti let – osud mu ale vyměřil o dvanáct méně. Pětidílná hudebně-dokumentární série Petra Ference přibližuje tvorbu Psích vojáků, Filipovu lásku k baroku a klasicismu i propojení s druhou generací českého literárního a hudebního undergroundu. Nechybí alter ego Kilián Nedory, rodinná anamnéza ani otisk jeho ryzí bytosti ve filmu Žiletky. Premiéra 12. 6.
On today’s episode, we are joined by Dr. Brad Topol, Distinguished Engineer and Director of Open Source Technologies at IBM, to talk about how to scale your leadership. We explore the process of how he went from individual contributor to distinguished engineer to director and executive. We chat about how you build a career... Read more »
On today’s episode, we are joined by Dr. Brad Topol, Distinguished Engineer and Director of Open Source Technologies at IBM, to talk about how to scale your leadership. We explore the process of how he went from individual contributor to distinguished engineer to director and executive. We chat about how you build a career... Read more »
Newt talks with Dr. Eric Topol about his new book, "Super Agers: An Evidence-Based Approach to Longevity." They discuss the revolution in human longevity driven by medical breakthroughs, highlighting the importance of addressing chronic diseases like diabetes, obesity, heart disease, cancer, and neurodegeneration earlier in life. Dr. Topol emphasizes a broader definition of a healthy lifestyle, incorporating factors such as pollution, loneliness, and social connection. He advocates for personalized nutrition over a one-size-fits-all approach and warns against the dangers of ultra-processed foods, which contribute to inflammation and age-related diseases. Their conversation also addresses the role of artificial intelligence in transforming healthcare from a reactive system to one focused on prevention, utilizing AI to assess individual risks and promote healthy aging. Dr. Topol discusses the significance of deep sleep, nature exposure, and social interactions in maintaining mental and physical health. Their discussion concludes with a call to action for a healthcare revolution, prioritizing prevention and lifestyle changes to extend health span and reduce healthcare costs.See omnystudio.com/listener for privacy information.
AGNTCY - Unlock agents at scale with an open Internet of Agents. Visit https://agntcy.org/ and add your support. What if AI could predict exactly when you'd get sick—and help you prevent it? In this episode of Eye on AI, Dr. Eric Topol, world-renowned cardiologist, author, and AI health pioneer, joins us to unveil the future of preventive medicine. We dive deep into the themes of his new book Super Agers, which lays out a groundbreaking blueprint for extending healthspan—not just lifespan—through the power of multimodal AI and deep biological data. Dr. Topol explains how AI models can now analyze a full-stack of human data—genomics, proteomics, metabolomics, microbiome, and more—to forecast age-related diseases like cancer, Alzheimer's, and heart disease decades before symptoms appear. This isn't science fiction. It's here now. If you're interested in the intersection of AI, longevity, and the future of medicine, this is a must-listen. Where AI Works tackles the big questions shaping AI's role in business today, cutting through the hype to deliver actionable insights for leaders. Brought to you by the Wharton School, in collaboration with Accenture, this podcast combines cutting-edge research with real-world case studies to uncover how top companies are using AI to upskill workforces, enhance customer experiences, boost productivity, and streamline operations. Check it out: https://link.cohostpodcasting.com/f5e223b4-da0c-4fc8-bbf3-5f24c15f8fd2?d=sxo9xhJN2 Stay Updated: Craig Smith on X:https://x.com/craigss Eye on A.I. on X: https://x.com/EyeOn_AI (00:00) The Power of Precision Medical Forecasting (01:53) Eric Topol's Journey into Digital & AI Medicine (03:27) Using AI to Prevent Aging-Related Diseases (05:25) The Challenge of Health Data Privacy & Ownership (09:05) Genetic Risk to Deep Data Insights (11:20) Personalized Prevention Through Lifestyle & Biomarkers (13:59) Why Anti-Aging Drugs Are Still Years Away (16:18) What are Organ Clocks (19:34) The Longevity Industry's Flawed Use of AI (21:59) Top AI Pioneers Endorse “Super Agers” (24:21) Which Longevity Startups Are Getting It Right? (26:27) Why Topol Refuses to Join Longevity Startups (28:57) Topol's Own Health Data & Lessons Learned (30:25) How Accurate Is AI at Predicting Disease Timing? (31:47) The Truth About Genetic Risk and Cancer Detection (33:33) AI-Driven Cancer Detection: A Smarter Approach (38:51) How Precision Medicine Has Evolved (41:02) The Risky Reality of Anti-Aging Interventions (44:39) Why Healthspan Matters More Than Lifespan
American healthcare is in crisis—but what if we could change the system by preventing disease before it starts?In this episode of the a16z Podcast, general partner Vijay Pande sits down with Dr. Eric Topol, founder and director of the Scripps Research Translational Institute and one of the most cited researchers in medicine, to explore the cutting edge of preventive healthcare and longevity science.Drawing from his new book Super Agers: An Evidence-Based Path to Longevity, Topol breaks down why understanding the biology of aging—not reversing it—is the key to preventing the “Big Three” age-related diseases: cancer, cardiovascular disease, and neurodegenerative conditions. The conversation spans AI-powered risk prediction, organ clocks, polygenic risk scores, GLP-1s, and the cultural and economic shifts required to move from a “sick care” system to one rooted in precision prevention and extended healthspan.If you've ever wondered how data, personalized medicine, and AI can add seven healthy years to your life—and what it will take to bring those benefits to everyone—this episode is for you. Resources: Find Eric on X: https://x.com/erictopolFind Vijay on X: https://x.com/vijaypande Stay Updated: Let us know what you think: https://ratethispodcast.com/a16zFind a16z on Twitter: https://twitter.com/a16zFind a16z on LinkedIn: https://www.linkedin.com/company/a16zSubscribe on your favorite podcast app: https://a16z.simplecast.com/Follow our host: https://twitter.com/stephsmithioPlease note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
What if the second half of life could be just as healthy, active, and fulfilling as the first? Drawing on the latest science, world-renowned cardiologist and researcher Dr. Eric Topol challenges outdated ideas about aging and reveals how factors like exercise, sleep, social connection and cutting-edge AI tools can help us extend not just our lifespan—but our healthspan. Dr. Topol joins The Excerpt to share insights from his new book "Super Agers: An Evidence-Based Approach to Longevity."Episode Transcript available hereSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Neste episódio, mergulhamos no fascinante universo da computação quântica — uma tecnologia que promete transformar tudo o que conhecemos sobre processamento de informação.Começamos do começo: o que é computação quântica e por que ela é tão diferente da computação tradicional? Explicamos conceitos como superposição, emaranhamento e a tal da decoerência quântica de um jeito direto, pra todo mundo entender.Depois, exploramos os diferentes tipos de qubits que estão sendo desenvolvidos no mundo real — de supercondutores a íons aprisionados — até chegarmos ao destaque do episódio: os qubits topológicos.Um papo pra quem quer entender não só o “como”, mas o “por que” dessa revolução tecnológica.Edição completa por Rádiofobia Podcast e Multimídia: https://radiofobia.com.br/---Nos siga no Twitter e no Instagram: @luizalabs @cabecadelabDúvidas, cabeçadas e sugestões, mande e-mail para o cabecadelab@luizalabs.comou uma DM no InstagramParticipantes: MARCOS NORIYUKI | https://www.linkedin.com/in/marcos-noriyuki-miyata/LAURO MILAGRES | https://www.linkedin.com/in/lauro16milagres/THAIS RIBEIRO | https://www.linkedin.com/in/thaisribeiron/Links interessantes:https://medium.com/@thaisplicando/6647b0edb28d
While promises of extending the human lifespan to 125 and beyond are premature, recent breakthroughs in the early detection of killer diseases of the major organs and brain offer a healthier old age – especially when paired with behavioral changes that Dr Topol calls “Lifestyle+.”
Today's episode could change (or save) your life. It's a must-listen. You'll hear from the world's leading longevity doctor about the simple, proven changes that will help you live longer, feel better, and prevent diseases like cancer, heart disease, and dementia. Today, Mel sits down with one of the world's most respected scientists, Dr. Eric Topol — a pioneering cardiologist, longevity researcher, and one of the top 10 most cited medical researchers alive today — to reveal the real, evidence-based approach to longevity. This is the science and art of living better, longer. Forget the trendy anti-aging supplements, infusions, and miracle cures: Dr. Topol is here to give you the truth on exactly what the science says about how to reverse the biological age of your organs, add up to a decade of healthy years to your life, and avoid the biggest killers we all fear. You'll learn: -The #1 free intervention proven to slow aging -The three everyday habits that are aging you faster (and how to fix them) -How to exercise and eat for optimal health and longevity -The truth about supplements, IV drips, and anti-aging clinics -Why loneliness is as dangerous to your health as smoking -How exercise can be more effective than antidepressants -The breakthrough blood tests and tools that could predict — and prevent — diseases decades before they happen This conversation is full of science and hope, because as Dr. Topol says: “It has never been a more exciting time in medicine.” Whether you want to prevent disease, feel better, or just live a longer, healthier life, this episode will give you the real plan for how to do it. If you love someone, send them this episode. It could save their life. For more resources, click here for the podcast episode. If you liked this episode, and you'll love listening to this one next: Look, Feel, & Stay Young Forever: #1 Orthopedic Surgeon's Proven ProtocolConnect with Mel: Get Mel's #1 bestselling book, The Let Them TheoryWatch the episodes on YouTubeFollow Mel on Instagram The Mel Robbins Podcast InstagramMel's TikTok Sign up for Mel's personal letter Subscribe to SiriusXM Podcasts+ to listen to new episodes ad-freeDisclaimer
CELÝ ROZHOVOR V DÉLCE 81 MIN. JEN NA HTTPS://HEROHERO.CO/CESTMIR A HTTPS://FORENDORS.CZ/CESTMIR „Dnes jsou na tom všichni docela špatně. Rozpad světového řádu způsobuje celou řadu tenzí. To, co se stalo v Americe, je ale výsledkem dlouhodobých tendencí,“ říká bývalý premiér Mirek Topolánek s tím, že ze současného dění není překvapen. Podle něj za zvolení Trumpa prezidentem mohou sami demokraté, protože svými příliš „wokistickými“ tématy naštvali spoustu lidí. Topolánek upozorňuje, že na druhé straně by lidé neměli tolik podléhat „výkřikům“ v médiích a na sociálních sítích a měli by si zachovat trochu odstup. Důvodem je i to, že jsme si podle něj zvykli žít v nejlepším období posledního tisíce let, a přesto nám připadá, že situace není dobrá. Svým způsobem podle něj máme pravdu, protože například v Česku už nežijeme v zemi, kterou Česká republika byla před dvěma nebo třemi lety, přestože se toho tolik nezměnilo. Topolánek vidí za současnou situací i nefunkčnost řady mezinárodních organizací, jako je Rada bezpečnosti OSN. „Mám z toho kopřivku. Třeba neschopnost dohody v EU naprosto eliminuje jakékoliv razantnější rozhodnutí, které doba, jež se na nás hrne, vyžaduje. A je ohrožena euroatlantická vazba, která udržovala svět v jakési rovnováze,“ naráží expremiér na stabilitu NATO. Podle Topolánka mají lidé v Evropě pocit, že demokracie selhává, a volají po silném vůdci – a i v Česku je to už podle něj nadpoloviční skupina lidí. Co s tím? Jak vnímá současnou českou politickou scénu před volbami? A co by voliči rozhodně neměli dělat, aby nevstoupili z bláta do louže? I to se dozvíte v rozhovoru.
Send us a textJoin Marla Dalton, PE, CAE, and William Schaffner, MD, for a fascinating conversation with cardiologist and renowned biomedical researcher Eric Topol, MD, on the revolutionary impact of artificial intelligence (AI) in medicine and healthcare. Topol shares how AI can help strengthen the patient-doctor relationship, enhance diagnostics, and reduce medical errors.Show notesA practicing cardiologist, Topol is chair and professor of Translational Medicine at Scripps Research. One of the most cited researchers in medicine, he has published several bestselling books on the future of medicine, including a new book that explores research transforming human longevity and chronic disease. He was elected to the National Academy of Medicine and was commissioned to lead a review of the UK National Health Service. Additionally, he is the editor-in-chief of Medscape and publishes the Substack newsletter, Ground Truths. Known for his groundbreaking studies on AI in medicine, genomics, and digitized clinical trials, Topol was named to the TIME100 Health list of the most influential people in health in 2024. Follow NFID on social media
„Narodil jsem se 1. dubna 1935 v Poříčí nad Sázavou, okres Benešov u Prahy. Můj otec je topičem ČSD. Oba moji dědové pracovali ve skále jako kameníci,“ cituji úvod dopisu Josefa Topola, který napsal ve svých 18 letech do divadla E. F. Burianovi.
„Narodil jsem se 1. dubna 1935 v Poříčí nad Sázavou, okres Benešov u Prahy. Můj otec je topičem ČSD. Oba moji dědové pracovali ve skále jako kameníci,“ cituji úvod dopisu Josefa Topola, který napsal ve svých 18 letech do divadla E. F. Burianovi.Všechny díly podcastu Názory a argumenty můžete pohodlně poslouchat v mobilní aplikaci mujRozhlas pro Android a iOS nebo na webu mujRozhlas.cz.
It is our deepest pleasure to bring you this episode on Norman Jewison's masterpiece of non-auteurism: Fiddler on the Roof. Both of the hosts have a long and complex relationship to both this film and its source material and could wax for hours on its rich humanism and craft. The tale of Tevye the Dairyman and his daughters remains as fascinating and exciting today as ever! We promise! This movie is not boring at all (except for maybe a couple scenes with Perchik). Topics include: changes from the original stories, Jerome Robbins' opening numbers, and a major change in Alana's life.
Al parecer los científicos no están muy convencidos de que Microsoft realmente haya desarrollado el qubit topológico Majorana, y piden detalles técnicos, ademas; Hackers del gobierno norcoreano introdujeron software espía en la tienda de aplicaciones de Android; Niantic, el creador de Pokémon Go, vende su división de juegos a Scopely, de propiedad saudí como todos los días les solicitamos sus comentarios. Hackers del gobierno norcoreano introdujeron software espía en la tienda de aplicaciones de Android http://www.lookout.com/threat-intelligence/article/lookout-discovers-new-spyware-by-north-korean-apt37 Motorola Edge 60 Fusion se filtra en renders de aspecto oficial https://x.com/evleaks/status/1899511260959641886 Niantic, el creador de Pokémon Go, vende su división de juegos a Scopely, de propiedad saudí https://www.engadget.com/mobile/pokemon-go-maker-niantic-sells-its-game-division-to-saudi-owned-scopely-160905447.html Google asegura a los propietarios de Chromecast que está trabajando para solucionar los problemas de transmisión https://phandroid.com/2025/03/12/google-assures-chromecast-owners-that-its-working-to-fix-streaming-issues/ La comunidad científica no cree a Microsoft sobre su qubit topológico Majorana https://www.reddit.com/r/Physics/comments/1iv6eko/microsoft_is_false_advertising_that_they_made/?rdt=45172 Video del día en las redes https://www.instagram.com/reel/DHHpK8FuNzy/ ESPERAMOS TUS COMENTARIOS...
Americký prezident Donald Trump podle všeho nařídil přerušit americkou vojenskou pomoc Ukrajině. Vedení Ukrajiny prý musí Trumpa přesvědčit, že chce jednat o míru, aby dodávky zbraní obnovil. „Pro Volodymyra Zelenského bude velmi složité se po tom fiasku v Oválné pracovně nějak omlouvat,” předpokládá v pořadu Osobnost Plus bývalý premiér a předseda ODS Mirek Topolánek.
Americký prezident Donald Trump podle všeho nařídil přerušit americkou vojenskou pomoc Ukrajině. Vedení Ukrajiny prý musí Trumpa přesvědčit, že chce jednat o míru, aby dodávky zbraní obnovil. „Pro Volodymyra Zelenského bude velmi složité se po tom fiasku v Oválné pracovně nějak omlouvat,” předpokládá v pořadu Osobnost Plus bývalý premiér a předseda ODS Mirek Topolánek.Všechny díly podcastu Osobnost Plus můžete pohodlně poslouchat v mobilní aplikaci mujRozhlas pro Android a iOS nebo na webu mujRozhlas.cz.
VIP pražské parkovací karty, Rozárka vs. Topol, kauza falešného tweetu Mirky Němcové, česká pivní kultura a vedle toho všeho zrušený tendr na dostavbu metra D, projektu atakující v celkové výši 100 miliard Kč. Mediální prostor bohužel opanují banality, důležité věci se neřeší. Je v tom úmysl nebo jen nekompetence? Briefing obsahuje i pasáž: „věděli jste, co všechno podporujeme z veřejného rozpočtu?” Který státní výdaj přijde nejzbytečnější vám?
This week, in honor of the cold movie month, we hit the slope with James Bond as we dust off the archives and talk For Your Eyes Only! Roger Moore beds a figure skater....classy! How will For Your Eyes Only hold up? Host: Nic Panel: Matt, Daniel, Jon Directed by John Glen Starring: Roger Moore, Carole Bouquet, Topol, Lynn-Holly Johnson, Julian Glover, Cassandra Harris, Jill Bennett, Michael Gothard, Lois Maxwell, Desmond Llewelyn
In “The Deserter,” Sarah A. Topol reports the story of Ivan, a captain in the Russian Army who fought in Ukraine and then ultimately fled the war and his country with his wife, Anna. Topol spoke to 18 deserters while reporting in eight countries across four continents over the last year and a half; their experiences helped paint a vivid picture of the Russian war operation and its corruption, chaos and brutality.Narrated by Liev Schreiber.“The Deserter” is a five-part special series in collaboration with The New York Times Magazine.
In “The Deserter,” Sarah A. Topol reports the story of Ivan, a captain in the Russian Army who fought in Ukraine and then ultimately fled the war and his country with his wife, Anna. Topol spoke to 18 deserters while reporting in eight countries across four continents over the last year and a half; their experiences helped paint a vivid picture of the Russian war operation and its corruption, chaos and brutality.Narrated by Liev Schreiber.“The Deserter” is a five-part special series in collaboration with The New York Times Magazine.All five parts of this audio feature can be found here or by searching for “The Deserter” on the NYT Audio app or wherever you get your podcasts.The text version of the story can be found here.