Podcasts about vander kooi

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.07.09.545606v1?rss=1 Authors: Aristizabal-Ramirez, I., Dragich, A. K., Giese, A. P. J., Zuluaga-Osorio, K. S., Watkins, J., Davies, G. K., Hadi, S. E., Riazuddin, S., Vander Kooi, C. W., Ahmed, Z. M., Frolenkov, G. I. Abstract: Calcium and Integrin-Binding Protein 2 (CIB2) is an essential subunit of the mechano-electrical transduction (MET) complex in mammalian auditory hair cells. CIB2 binds to MET channel subunits TMC1/2 and is required for their transport and/or retention at the tips of mechanosensory stereocilia. Since genetic ablation of CIB2 results in complete loss of MET currents, the exact role of CIB2 in the MET complex remains elusive. Here, we generated a new mouse strain with deafness-causing p.R186W mutation in Cib2 and recorded small but still measurable MET currents in the cochlear outer hair cells at postnatal days 4-8. We found that p.R186W mutation results in increase of the resting open probability of MET channels, steeper MET current dependence on hair bundle deflection (I-X curve), loss of fast adaptation, and increased leftward shifts of I-X curves upon hair cell depolarization. Combined with AlphaFold2 prediction that p.R186W disrupts one of the multiple interacting sites between CIB2 and TMC1/2, our data suggest that CIB2 mechanically constrains TMC1/2 conformations to ensure proper force sensitivity and dynamic range of the MET channels. Using a custom piezo-driven stiff probe deflecting the hair bundles in less than 10 s, we also found that p.R186W mutation slows down the activation of MET channels. This phenomenon, however, is unlikely to be the direct effect on MET channels, since we also observed p.R186W-evoked disruption of the electron-dense material at the tips of mechanotransducing stereocilia and the loss of membrane-shaping BAIAP2L2 protein from the same location. We concluded that p.R186W mutation in CIB2 disrupts force sensitivity of the MET channels and force transmission to these channels. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

A new MP3 sermon from First Christian Reformed Church is now available on SermonAudio with the following details: Title: Funeral Of Daryl Vander Kooi Speaker: Rev. Dr. Wayne Kobes Broadcaster: First Christian Reformed Church Event: Funeral Service Date: 11/12/2022 Length: 70 min.

Vince Vander Kooi was nominated as a Beck's Player with Heart for his efforts on and off the field. Vince's favorite thing about high school sports is the adrenaline, competitive nature, and sportsmanship of everyone involved. To Vince, agriculture is more than just a job, you have to have a true passion for it. Vince is involved in football, FFA, and 4-H, and partakes in many community service activities. After graduation, Vince would like to attend college for something ag related, then return to his family farm. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In today's podcast, we welcome to the show Arizona Bass Fishing Guide and Co-Host of the Angler's Happy Hour Podcast, Rob Vander Kooi! We are going to be talking about bass fishing in Arizona, Spinnerbaits and much more! Rob's Instagram: https://www.instagram.com/rob_vanderkooi/ Angler's Happy Hour Podcast: https://www.anglershappyhour.com/ Thanks for watching! Comment, Like and SUBSCRIBE! If you would like to support the Serious Angler Podcast, here is how: PayPal: paypal.me/baileyeigbrett Venmo: @SeriousAngler Want Serious Angler apparel? Click the link below to purchase! https://teamlocker.squadlocker.com/#/lockers/serious-anglers?_k=xbhyts Follow Along On Serious Angler Social Media: Instagram: seriousangler Facebook: Serious Angler Podcast YouTube: Serious Angler Podcast ---------------- If you'd like to take your tackle organization game to the next level, get yourself some Lure Lock Tackle Boxes! Hard to be the customization of TakLogic Technology. Use Code: "SeriousAngler20" for 20% Off Lure Lock Tackle Boxes Want Premium Tungsten Jigs and Terminal Tackle? Check out Queen Tackle Receive 20% off at Queen Tackle, use code: "seriousangler20" Click here to order: https://www.queentackle.com/ Want some Coffee geared toward the everyday Outdoorsman? Check out Outdoorsman Coffee Co. and get 15% off using code "SERIOUSANGLER" at: https://outdoorsmancoffee.com/ Have any boating or kayak needs? Give Morgan Marine a call and they will get you set up! Click the link below: https://www.morganmarine.net/ Are you looking to get yourself into the most efficient and highest rated fishing kayak? Check out Hobie Kayaks at: https://www.hobie.com/kayaks/ Want to get yourself the best performance fishing apparel to overcome anything that Mother Nature throws at you? Get yourself some AFTCO gear at: https://aftco.com/?gclid=CjwKCAiA6aSABhApEiwA6Cbm_3hbFaTSf5jPOL7KuIHwKdQb7x0VaPAYtGq2tXSH8AIIuaTrl0TjnBoCkxYQAvD_BwE -------------- Follow Our Personal Social Media: Instagram: https://www.instagram.com/bailey_eigbrett/ Instagram: https://www.instagram.com/fullfishingguideservice/ Twitter: https://twitter.com/bailey_eigbrett Facebook: https://www.facebook.com/bailey.eigbrett/ Facebook: https://www.facebook.com/Fullfishingguideservice/ ----- Want assistance with Social Media, Website Creation, Podcasting, Content Creation and MORE? Check out Serious Angler Media Services! https://www.seriousanglermedia.com/ ----- #SeriousAngler #SeriousAnglerPodcast #BassFishing --- Support this podcast: https://anchor.fm/serious-angler/support

Don’t be the Weird Guy at the barbeque. Change sales successfully with effective company culture. Transform your sales team from order takers to quarter breakers, significantly increase revenue, and create scalable sales systems. In today’s episode, Daniel Vander Kooi, Founder/CEO of Manna Insurance Group, and I talked about how to build companies through his quote […]

Communication, community, and freedom are 3 of the things that Dan provides as a leader of his organization. In this episode, Dan shares how this has empowered his team to amazing success. Dan is an example of what happens when a visionary leader surrounds themselves with people that can catch the vision, own it, and achieve amazing things. Dan is a dreamer! He loves working on ideas and getting the ball rolling and then handing it off to the team of amazingly talented people around him to implement. Often times these ideas revolve around baseball, insurance, marketing and Eagles Nest International (children's home in Guatemala).Daniel Vander Kooi is a business owner and entrepreneur living in the very small town of Lynden, Washington. The phrase, “Culture is King”, that we have heard so often, is really taken and applied to each area Dan spends his time in.He is husband and dad of 3 kids, owner, and partner of 3 different businesses, Board President of Eagles Nest International- an orphanage in Guatemala, and on top of that, he is a varsity high school baseball coach. Like many business owners, spreading his time and energy in so many directions can present a challenge.However, over the last 11 years, Dan has shifted his approach to focus on building strong teams around him that thrive on healthy cultures. His method has proven to be financially and personally beneficial to each industry and area of life he is invested in. Not only has he found freedom for growth in his businesses and opportunities to give back to communities, but he has also been able to find more quality time in his favorite job, Dad.To connect with Dan, you can visit any of the links below. Also, please make sure to join our new LinkedIn group where you can connect with many of my former guests and fellow listeners. Visit http://bit.ly/sagemindset to join the group and go deeper with guests and fellow listeners!  www.mannainsurancegroup.com,www.linedrivenw.com,www.ironbrandconsulting.comhttps://www.linkedin.com/in/danielvanderkooi/

Even though many landscape contractors have been in business for 5, 10 or even 20 years, they still overlook the fundamentals when it comes to running their businesses. This causes them to improperly price work, month after month and year after year, not knowing whether they made money or lost money until the end of the year. Whether you're new to the green industry or a seasoned professional looking for a business basics refresher course, you must listen in tonight as Marcus vandeVliet walks us through the five business necessities that you must have to remain competitive and profitable - both now and in the future. 1. Why you must have a business plan 2. How to create a realistic budget 3. The importance of an accurate estimating system 4. Job costing basics 5. What is an information management system Marcus vandeVliet is the founder of a design build company in New Jersey that he re-directed into a niche business specializing in project management of high-end projects for the residential marketplace. He developed and improved accounting and information transfer systems to help maximize profitability of a large landscaping company with 400 employees and $23 million in revenues. He was President of a residential design build firm, improving profitability from 6 percent to 19 percent while maintaining the company's $7 million in revenues. VandeVliet is recognized as an expert in bidding and estimating in the construction industry when working with Vander Kooi and Associates and delivered presentations and conducted workshops throughout the United States. He has put his insight and experience to work for a broader swath of businesses by founding MV Consulting, now MV Enterprises. Through Power PlanningTM, Performance Consultation, and Public Speaking, he is dedicated to helping clients improve performance and profitability to realize their potential and achieve long-term growth and sustainability. For more information, visit MV Enterprises at www.mventerprises.biz.

Even though many landscape contractors have been in business for 5, 10 or even 20 years, they still overlook the fundamentals when it comes to running their businesses. This causes them to improperly price work, month after month and year after year, not knowing whether they made money or lost money until the end of the year.Whether you're new to the green industry or a seasoned professional looking for a business basics refresher course, you must listen in tonight as Marcus vandeVliet walks us through the five business necessities that you must have to remain competitive and profitable - both now and in the future. 1. Why you must have a business plan 2. How to create a realistic budget 3. The importance of an accurate estimating system 4. Job costing basics 5. What is an information management systemMarcus vandeVliet is the founder of a design build company in New Jersey that he re-directed into a niche business specializing in project management of high-end projects for the residential marketplace. He developed and improved accounting and information transfer systems to help maximize profitability of a large landscaping company with 400 employees and $23 million in revenues. He was President of a residential design build firm, improving profitability from 6 percent to 19 percent while maintaining the company's $7 million in revenues.VandeVliet is recognized as an expert in bidding and estimating in the construction industry when working with Vander Kooi and Associates and delivered presentations and conducted workshops throughout the United States. He has put his insight and experience to work for a broader swath of businesses by founding MV Consulting, now MV Enterprises. Through Power PlanningTM, Performance Consultation, and Public Speaking, he is dedicated to helping clients improve performance and profitability to realize their potential and achieve long-term growth and sustainability.For more information, visit MV Enterprises at www.mventerprises.biz.

Even though many landscape contractors have been in business for 5, 10 or even 20 years, they still overlook the fundamentals when it comes to running their businesses. This causes them to improperly price work, month after month and year after year, not knowing whether they made money or lost money until the end of the year.Whether you're new to the green industry or a seasoned professional looking for a business basics refresher course, you must listen in tonight as Marcus vandeVliet walks us through the five business necessities that you must have to remain competitive and profitable - both now and in the future. 1. Why you must have a business plan 2. How to create a realistic budget 3. The importance of an accurate estimating system 4. Job costing basics 5. What is an information management systemMarcus vandeVliet is the founder of a design build company in New Jersey that he re-directed into a niche business specializing in project management of high-end projects for the residential marketplace. He developed and improved accounting and information transfer systems to help maximize profitability of a large landscaping company with 400 employees and $23 million in revenues. He was President of a residential design build firm, improving profitability from 6 percent to 19 percent while maintaining the company's $7 million in revenues.VandeVliet is recognized as an expert in bidding and estimating in the construction industry when working with Vander Kooi and Associates and delivered presentations and conducted workshops throughout the United States. He has put his insight and experience to work for a broader swath of businesses by founding MV Consulting, now MV Enterprises. Through Power PlanningTM, Performance Consultation, and Public Speaking, he is dedicated to helping clients improve performance and profitability to realize their potential and achieve long-term growth and sustainability.For more information, visit MV Enterprises at www.mventerprises.biz.

Even though many landscape contractors have been in business for 5, 10 or even 20 years, they still overlook the fundamentals when it comes to running their businesses. This causes them to improperly price work, month after month and year after year, not knowing whether they made money or lost money until the end of the year. Whether you're new to the green industry or a seasoned professional looking for a business basics refresher course, you must listen in tonight as Marcus vandeVliet walks us through the five business necessities that you must have to remain competitive and profitable - both now and in the future. 1. Why you must have a business plan 2. How to create a realistic budget 3. The importance of an accurate estimating system 4. Job costing basics 5. What is an information management system Marcus vandeVliet is the founder of a design build company in New Jersey that he re-directed into a niche business specializing in project management of high-end projects for the residential marketplace. He developed and improved accounting and information transfer systems to help maximize profitability of a large landscaping company with 400 employees and $23 million in revenues. He was President of a residential design build firm, improving profitability from 6 percent to 19 percent while maintaining the company's $7 million in revenues. VandeVliet is recognized as an expert in bidding and estimating in the construction industry when working with Vander Kooi and Associates and delivered presentations and conducted workshops throughout the United States. He has put his insight and experience to work for a broader swath of businesses by founding MV Consulting, now MV Enterprises. Through Power PlanningTM, Performance Consultation, and Public Speaking, he is dedicated to helping clients improve performance and profitability to realize their potential and achieve long-term growth and sustainability. For more information, visit MV Enterprises at www.mventerprises.biz.

Marcus vandeVliet of MV Enterprises discusses job costing, including why you need to job cost, how to set up your estimating system for job costing, the major risk involved with job costing, types of info you can obtain through job costing, and much more! VandeVliet is the founder of a design build company in New Jersey that he re-directed into a niche business specializing in project management of high-end projects for the residential marketplace. He developed and improved accounting and information transfer systems to help maximize profitability of a large landscaping company with 400 employees and $23 million in revenues. He was president of a residential design build firm, improving profitability from 6 percent to 19 percent while maintaining the company's $7 million in revenues. Marcus is recognized as an expert in bidding and estimating in the construction industry who worked with Vander Kooi and Associates and delivered presentations and conducted workshops throughout the United States. He has put his insight and experience to work for a broader swath of businesses by founding MV Consulting, now MV Enterprises. Through Power Planning, performance consultation, and public speaking, he is dedicated to helping clients improve performance and profitability to realize their potential and achieve long-term growth and sustainability. In addition to this, Marcus works as a business consultant with DynaSCAPE and helped develop "DynaSCAPE Manage 360," a software program that integrates with DynaSCAPE design software. Manage 360 provides you with the business management tools to necessary to estimate the design, manage the installation and also integrates with your business accounting software providing you with a complete design and business solution. For more information, visit http://mventerprises.biz or email marcus@mventerprises.biz.

Marcus vandeVliet of MV Enterprises discusses job costing, including why you need to job cost, how to set up your estimating system for job costing, the major risk involved with job costing, types of info you can obtain through job costing, and much more!VandeVliet is the founder of a design build company in New Jersey that he re-directed into a niche business specializing in project management of high-end projects for the residential marketplace. He developed and improved accounting and information transfer systems to help maximize profitability of a large landscaping company with 400 employees and $23 million in revenues. He was president of a residential design build firm, improving profitability from 6 percent to 19 percent while maintaining the company's $7 million in revenues. Marcus is recognized as an expert in bidding and estimating in the construction industry who worked with Vander Kooi and Associates and delivered presentations and conducted workshops throughout the United States. He has put his insight and experience to work for a broader swath of businesses by founding MV Consulting, now MV Enterprises. Through Power Planning, performance consultation, and public speaking, he is dedicated to helping clients improve performance and profitability to realize their potential and achieve long-term growth and sustainability.In addition to this, Marcus works as a business consultant with DynaSCAPE and helped develop "DynaSCAPE Manage 360," a software program that integrates with DynaSCAPE design software. Manage 360 provides you with the business management tools to necessary to estimate the design, manage the installation and also integrates with your business accounting software providing you with a complete design and business solution.For more information, visit http://mventerprises.biz or email marcus@mventerprises.biz.

Marcus vandeVliet of MV Enterprises discusses job costing, including why you need to job cost, how to set up your estimating system for job costing, the major risk involved with job costing, types of info you can obtain through job costing, and much more!VandeVliet is the founder of a design build company in New Jersey that he re-directed into a niche business specializing in project management of high-end projects for the residential marketplace. He developed and improved accounting and information transfer systems to help maximize profitability of a large landscaping company with 400 employees and $23 million in revenues. He was president of a residential design build firm, improving profitability from 6 percent to 19 percent while maintaining the company's $7 million in revenues. Marcus is recognized as an expert in bidding and estimating in the construction industry who worked with Vander Kooi and Associates and delivered presentations and conducted workshops throughout the United States. He has put his insight and experience to work for a broader swath of businesses by founding MV Consulting, now MV Enterprises. Through Power Planning, performance consultation, and public speaking, he is dedicated to helping clients improve performance and profitability to realize their potential and achieve long-term growth and sustainability.In addition to this, Marcus works as a business consultant with DynaSCAPE and helped develop "DynaSCAPE Manage 360," a software program that integrates with DynaSCAPE design software. Manage 360 provides you with the business management tools to necessary to estimate the design, manage the installation and also integrates with your business accounting software providing you with a complete design and business solution.For more information, visit http://mventerprises.biz or email marcus@mventerprises.biz.

Marcus vandeVliet of MV Enterprises discusses job costing, including why you need to job cost, how to set up your estimating system for job costing, the major risk involved with job costing, types of info you can obtain through job costing, and much more! VandeVliet is the founder of a design build company in New Jersey that he re-directed into a niche business specializing in project management of high-end projects for the residential marketplace. He developed and improved accounting and information transfer systems to help maximize profitability of a large landscaping company with 400 employees and $23 million in revenues. He was president of a residential design build firm, improving profitability from 6 percent to 19 percent while maintaining the company's $7 million in revenues. Marcus is recognized as an expert in bidding and estimating in the construction industry who worked with Vander Kooi and Associates and delivered presentations and conducted workshops throughout the United States. He has put his insight and experience to work for a broader swath of businesses by founding MV Consulting, now MV Enterprises. Through Power Planning, performance consultation, and public speaking, he is dedicated to helping clients improve performance and profitability to realize their potential and achieve long-term growth and sustainability. In addition to this, Marcus works as a business consultant with DynaSCAPE and helped develop "DynaSCAPE Manage 360," a software program that integrates with DynaSCAPE design software. Manage 360 provides you with the business management tools to necessary to estimate the design, manage the installation and also integrates with your business accounting software providing you with a complete design and business solution. For more information, visit http://mventerprises.biz or email marcus@mventerprises.biz.

Tonight, Marcus vandeVliet will discuss landscape business basics. Even though many landscape contractors have been in business for 5, 10 or even 20 years, they still overlook the fundamentals when it comes to running their businesses. This causes them to improperly price work, month after month and year after year, not knowing whether they made money or lost money until the end of the year.Whether you're new to the green industry or a seasoned professional looking for a business basics refresher course, you must listen in tonight as Marcus Vandevliet walks us through the five business necessities that you must have to remain competitive and profitable - both now and in the future.Tonight we will discuss such topics asWhy you must have a business planHow to create a realistic budgetThe importance of an accurate estimating systemJob costing basicsWhat is an information management system

Tonight, Marcus vandeVliet will discuss landscape business basics. Even though many landscape contractors have been in business for 5, 10 or even 20 years, they still overlook the fundamentals when it comes to running their businesses. This causes them to improperly price work, month after month and year after year, not knowing whether they made money or lost money until the end of the year.Whether you're new to the green industry or a seasoned professional looking for a business basics refresher course, you must listen in tonight as Marcus Vandevliet walks us through the five business necessities that you must have to remain competitive and profitable - both now and in the future.Tonight we will discuss such topics asWhy you must have a business planHow to create a realistic budgetThe importance of an accurate estimating systemJob costing basicsWhat is an information management system