Podcast appearances and mentions of David E Nichols

The greatest living psychedelic chemist Dr. David E. Nichols tells the story of his life in research while synthesizing a novel lysergamideTop Tree Herbs Kratom Tea Bags Top Tree Herbs is the first kratom tea bag companyLucy Tobacco Free Nicotine Lucy's mission is to reduce tobacco-related harm to zero.Support the show

In this interview I talk with the great medicinal chemist Dr. Robert Oberlender, he is the inventor of the multi-billion dollar blockbuster drug vyvanse and a ten year veteran of the David E. Nichols laboratory responsible for the synthesis and evaluation of a number psychedelics and empathogens such DOsB, DOiB, MDAI, and many others. The Ian Parker article I mentioned about the embittered ambien inventor:https://www.newyorker.com/magazine/2013/12/09/the-big-sleep-2Lucy Tobacco Free Nicotine Lucy's mission is to reduce tobacco-related harm to zero.Matcha.com Andrew Weil MD's matcha tea company. Use the code "Hamilton" for up to 20% off + a FREE gift.Apollo Wearable Save 10% on the Apollo wearable with coupon code HAMILTONSupport the show

In this week's Safe Home Podcast, Beth talks with Tamara Gabbard. She lives in the jungles of Costa Rica with her toddler Rubi-Jean. Tamara is a Copywriter and Content Marketing Strategist, and she also identifies as a Soul Consultant and Clairvoyant. She combines her skills in both the practical and spiritual realms to help people who are struggling to break through the overwhelm that life can bring when trying to make an impact on the world. Like our son Joey, Tamara has done extensive personal research with psychedelics and other substances. She's 5 years sober now, but she uses some of the things she learned through her psychedelic trips to inform her work, especially finding the root causes of whatever obstacle people get stuck on. Tamara's story is pretty extraordinary. Even if you can't relate to her exact experience, I know you will be inspired by her talk to dig a little deeper to help yourself and your struggling teen. ===============

In this week's Safe Home Podcast, Beth talks with Tamara Gabbard. She lives in the jungles of Costa Rica with her toddler Rubi-Jean. Tamara is a Copywriter and Content Marketing Strategist, and she also identifies as a Soul Consultant and Clairvoyant. She combines her skills in both the practical and spiritual realms to help people who are struggling to break through the overwhelm that life can bring when trying to make an impact on the world. Like our son Joey, Tamara has done extensive personal research with psychedelics and other substances.  She's 5 years sober now, but she uses some of the things she learned through her psychedelic trips to inform her work, especially finding the root causes of whatever obstacle people get stuck on. Tamara's story is pretty extraordinary. Even if you can't relate to her exact experience, I know you will be inspired by her talk to dig a little deeper to help yourself and your struggling teen. ===============

Neste episódio, vamos falar sobre a pesquisa com psicodélicos, no Brasil e no mundo. Conversamos com Uros Laban e Sidarta Ribeiro. Uros Laban é especialista na síntese de compostos químicos, incluindo substâncias psicodélicas. Uros fez o doutorado na Purdue University, nos Estados Unidos, onde David E. Nichols liderou um dos laboratórios que abriram caminho para a moderna pesquisa com psicodélicos, e depois fez seu trabalho de pós-doutorado na Universidade Federal do Rio de Janeiro. Sidarta Ribeiro é neurocientista, professor titular e vice-diretor do Instituto do Cérebro da Universidade Federal do Rio Grande do Norte e um dos principais nomes da pesquisa com psicodélicos no Brasil. Sidarta é autor de mais de 100 artigos científicos e de 5 livros de divulgação científica e ficção, o último deles lançado em 2019, O Oráculo da Noite: A história e a Ciência do Sonho.

In a departure from kratom science, Dr. Cachat and Brian look at a paper by a pioneering pharmacologist and researcher in the field of psychedelics, Dr. David E. Nichols. Dr. Nichols methodically lays out his case for why endogenous DMT produced in the pineal gland, brain, or other parts of the human body is not … Journal Club #18: Pineal Gland and DMT Facts and Myth Read More » The post Journal Club #18: Pineal Gland and DMT Facts and Myth first appeared on Kratom Science.

A special treat this week as the two titans of psychopharmacology discuss the medicinal chemistry of psychedelics. Dr Nichols is the Founding President of the Heffter Research Institute, an organisation designed to promote research of the highest scientific quality with psychedelics in order to contribute to a greater understanding of the mind leading to the improvement of the human condition, and to alleviate suffering.Professor Nutt and Dr Nichols answer some burning questions of psychedelic science such as: What will come to market first, LSD, Psilocybin or MDMA? Could microdosing be dangerous? Is there such a thing as DMT tolerance? David E. Nichols, is currently an Adjunct Professor in the Eshelman School of Pharmacy at the University of North Carolina, Chapel Hill, NC. He is a Distinguished Professor Emeritus at the Purdue University College of Pharmacy, and was the Robert C. and Charlotte P. Anderson Chair in Pharmacology, where he carried out teaching and research for 38 years prior to his retirement in 2012. A major focus of his research was on substances known as hallucinogens, known more popularly as psychedelics. Widely published in the scientific literature and internationally recognized for his research on centrally active drugs, he has studied all of the major classes of psychedelic agents, including LSD and other lysergic acid derivatives, psilocybin and the tryptamines, and phenethylamines related to mescaline. Among scientists, he is recognized as one of the foremost international experts on the medicinal chemistry of psychedelics.Shulgin Mescaline MDMA LSD Psilocybin Entactogen vs Empathogen Drugs Enforcement Agency Salvia Heffter Research Institute Arthur Heffter Psilocybin for depression trial Psilocybin for OCD Yale study Psilocybin-assisted Group Therapy for Demoralization in Long-term AIDS SurvivorsN,N-dimethyltryptamine and the pineal gland: Separating fact from mythA Model for the Application of Target-Controlled Intravenous Infusion for a Prolonged Immersive DMT Psychedelic ExperienceFen-phen Weightloss drug Synthesis and Biological Evaluation of Tryptamines Found in Hallucinogenic Mushrooms: Norbaeocystin, Baeocystin, Norpsilocin, and AeruginascinBecome a Drug Science Community Member: https://www.donate.drugscience.org.uk/Twitter: @ProfDavidNutt @Drug_ScienceA Fascinate Productions podcast for Drug Science ★ Support this podcast ★

Taken from the Psychedelic Science '13 conference this epic talk from Heffter Research Institute Founder, David E. Nichols, explores the depths of the brains relationship with LSD.  This talk will provide a foundation for understanding the importance of 5-HT2A receptors in the brain, now widely believed to be the key brain target for psychedelics. The study of this G protein-coupled receptor (GPCR) has required research efforts across several disciplines. Although it was initially thought to couple only to Gq, leading to activation of phospholipase C, it is now known to couple to multiple intracellular signaling pathways. The unique psychopharmacological properties of psychedelics clearly demonstrate that this receptor has special importance as a critical component of sensory perception in humans, and by extension, may be a key player in mediating consciousness.  David E. Nichols is the founding president of the Heffter Research Institute, named after German chemist and pharmacologist Arthur Heffter, who first discovered that mescaline was the active component in the peyote cactus. In 2004 he was named the Irwin H. Page Lecturer by the International Serotonin Club, and delivered an address in Portugal titled, "35 years studying psychedelics: what a long strange trip it's been." Among pharmacologists, he is considered to be one of the world's top experts on psychedelics. Nichols's other professional activities include teaching medicinal chemistry and molecular pharmacology at Purdue University in West Lafayette, IN, and teaching medical students at the Indiana University School of Medicine.

Dr. David E. Nichols, M.D. was seen in the documentary DMT: The Spirit Molecule for his role and aid in the creation of dimethyltryptamine (DMT) for use in Dr. Rick Strassman's research trials in the book. We discuss MDMA, psilocybin and the future of depression treatments. My wellness program is almost finished. Check notjustpaleo.com and join the newsletter to stay up to date.