Podcasts about Journal club

Send a textBen and Daphna conclude Journal Club with a quality improvement study from Pediatrics titled "Improving Health-Related Social Needs Screening and Support Across a Pediatric Health Care System". The hosts discuss the successful implementation of universal social determinants of health (SDOH) screening across nine pediatric divisions at Levine Children's. They highlight the impressive results—screening compliance reaching 92%—and the practical impact of connecting families to resources like FindHelp.org, which led to a 56% resolution rate in food insecurity for positive screens. Daphna makes a personal commitment to improve resource accessibility in her own unit.----Improving Health-Related Social Needs Screening and Support Across a Pediatric Health Care System. Laroia R, Minor W, Carr A, Buitrago Mogollon T, White BB, Mabus S, Stilwell L, Ahmed A, Mehta S, Obita T, Reed S, Senturias Y, Mittal S, Horstmann S, Demmer L, Dantuluri K, Chadha A, Noonan L, Courtlandt C.Pediatrics. 2026 Feb 5:e2024070035. doi: 10.1542/peds.2024-070035. Online ahead of print.PMID: 41638605Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

In this episode of the Award-winning PRS Journal Club Podcast, 2026 Resident Ambassadors to the PRS Editorial Board – Lucas Harrison, Christopher Kalmar, and Priyanka Naidu- and special guest, Scott P. Bartlett, MD, discuss the following articles from the February 2026 issue: "Anthropometrics versus Experts' Subjective Analysis of Cleft Severity and PSIO Outcomes in Unilateral Clefts: A Proposal for a New Grading" by Tanikawa, Chong, Fisher, et al. "A Modified Method for Ear Projection in Auricular Reconstruction: Split-Thickness Skin Graft Combined with Retroauricular Fascia Flap for Postauricular Coverage" by Li, Feng, Hu, et al. "Total Ear Reconstruction with Costal Cartilage  in Challenging Cases: Silicone-Induced Vascularized Capsule Technique" by Park.  Special guest Dr. Scott P. Bartlett. Dr. Bartlett is one of the world's leading craniofacial surgeons and serves as Director of the Craniofacial Program and an attending surgeon in the Division of Plastic, Reconstructive, and Oral Surgery at the Children's Hospital of Philadelphia. He is also a Professor of Surgery at the Perelman School of Medicine at the University of Pennsylvania and holds the prestigious Mary Downs Endowed Chair in Pediatric Craniofacial Treatment and Research at CHOP. Dr. Bartlett's clinical expertise encompasses congenital and acquired deformities of the skull, face, jaws, and ears, as well as complex facial aesthetic and reconstructive surgery. He served two terms as Section Editor for the Pediatric Craniofacial Section of Plastic and Reconstructive Surgery. His research portfolio includes landmark contributions to facial growth and development, age-related facial structural changes, non-surgical correction of ear deformities, and the use of advanced imaging and implant materials to improve operative planning and long-term outcomes. READ the articles discussed in this podcast as well as free related content: https://bit.ly/JCFeb26Collection The views expressed by hosts and guests are their own and do not necessarily reflect the official policies or positions of ASPS.

Send a textBen and Daphna review a randomized controlled trial published in The Journal of Pediatrics by Dr. Ariel Salas and colleagues at UAB. The study investigates whether early high-dose vitamin D supplementation (800 IU/day starting day 1) in extremely preterm infants reduces the incidence of Bronchopulmonary Dysplasia (BPD) compared to standard care (starting day 14). The hosts discuss the physiologic rationale linking vitamin D to lung development, the use of impulse oscillometry to measure lung mechanics, and the secondary findings regarding metabolic bone disease. They explore why the "physiologic rationale" doesn't always translate to clinical significance.----Early Vitamin D Supplementation in Infants Born Extremely Preterm and Fed Human Milk: A Randomized Controlled Trial. Salas AA, Argent T, Jeffcoat S, Tucker M, Ashraf AP, Travers CP.J Pediatr. 2025 Dec;287:114754. doi: 10.1016/j.jpeds.2025.114754. Epub 2025 Jul 24.PMID: 40714046 Clinical Trial.Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Send a textIn this episode of Journal Club, Ben and Daphna review a retrospective cohort study from Pediatrics examining antibiotic duration for uncomplicated Gram-negative bloodstream infections in the NICU. The study, a collaboration between Nationwide Children's Hospital and UT Health San Antonio, compares outcomes between short course (≤8 days) and long course (≥9 days) therapy. The hosts discuss the startling finding that while recurrence rates were similar, the long-duration group had a 14% rate of developing multi-drug resistant (MDR) infections within 90 days, compared to 0% in the short-duration group.----Duration of Antibiotic Therapy for Gram-Negative Bloodstream Infections in the Neonatal Intensive Care Unit. Djordjevich CJ, Magers J, Cantey JB, Prusakov P, Sánchez PJ.J Pediatr. 2026 Jan 17:114993. doi: 10.1016/j.jpeds.2026.114993. Online ahead of print.PMID: 41554433 Free article.Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Send a textIn this episode of Journal Club, Ben and Daphna review a thought-provoking study from the Archives of Disease in Childhood titled "Chest Compression in Newborn Infants: What Anatomical Structures Are We Compressing?". The hosts explore the anatomical findings suggesting that current neonatal CPR guidelines—recommending compressions over the lower third of the sternum—may actually be targeting the right ventricle and great veins rather than the left ventricle. They discuss the implications for the "cardiac pump" vs. "thoracic pump" theories and what this means for the future of resuscitation guidelines.----Chest compression in newborn infants: what anatomical structures are we compressing? Chua CT, O'Reilly M, Surak A, Schmölzer GM.Arch Dis Child Fetal Neonatal Ed. 2026 Jan 16:fetalneonatal-2025-329582. doi: 10.1136/archdischild-2025-329582. Online ahead of print.PMID: 41545184Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

In this Journal Club edition of the EAU Podcast, Prof. Thomas Tailly leads a focused discussion on the recently completed APPEAL trial, a multicentre randomised controlled study evaluating whether routine antibiotic prophylaxis is necessary for patients undergoing extracorporeal shock wave lithotripsy (ESWL).The distinguished panel - Prof. Kari Tikkinen, Prof. Zafer Tandogdu, Dr. Daron Smith, and Dr. Guido Kamphuis - explores the study's design, recruitment challenges, outcome measures and the rationale behind examining antibiotic use in a procedure historically considered low-risk for infection.They discuss variations in practice across centres, the balance between preventing rare infectious complications and avoiding unnecessary antibiotic exposure, and how the trial contributes valuable evidence in an area with limited high-quality data.Throughout the episode, the panel reflects on how these findings align with current EAU recommendations and considers how the APPEAL trial can support future refinements in guideline statements. With a mix of expert insight, clinical reasoning and constructive debate, this episode offers listeners a clear understanding of the trial's significance and its potential impact on everyday urological practice.You can find the article to the APPEAL trial here. For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

How did patients with PDR fare after being lost to follow-up for at least 1 year and then returning to the clinic? Kyle Kovacs, MD, is joined by Matt Starr, MD, and Nita Valikodath, MD, MS, to explore a recent paper that leveraged the power the IRIS Registry to assess real-world outcomes for this important subset of patients. 

This week Paula and I discuss a research paper about knitting and attention in children.Sonnier F, Lussiana E and Gueraud S (2023) Boosting inhibition control process by knitting at school. Front. Psychol. 14:1062001. doi: 10.3389/fpsyg.2023.1062001This study is specifically focussed on whether knitting can affect our executive function skills, and found that primary school children had significant better scores on a test of inhibition after 20 minutes of knitting compared to spending 20 minutes at recess. They also found that knitting reduced the impact of emotion on response times.You can read the full text here -------------

In this episode of the Award-winning PRS Journal Club Podcast, 2026 Resident Ambassadors to the PRS Editorial Board – Lucas Harrison, Christopher Kalmar, and Priyanka Naidu- and special guest, Scott P. Bartlett, MD, discuss the following articles from the February 2026 issue: "Total Ear Reconstruction with Costal Cartilage in Challenging Cases: Silicone-Induced Vascularized Capsule Technique" by Park. Read the article for FREE: https://bit.ly/TotalEarRecon Special guest Dr. Scott P. Bartlett. Dr. Bartlett is one of the world's leading craniofacial surgeons and serves as Director of the Craniofacial Program and an attending surgeon in the Division of Plastic, Reconstructive, and Oral Surgery at the Children's Hospital of Philadelphia. He is also a Professor of Surgery at the Perelman School of Medicine at the University of Pennsylvania and holds the prestigious Mary Downs Endowed Chair in Pediatric Craniofacial Treatment and Research at CHOP. Dr. Bartlett's clinical expertise encompasses congenital and acquired deformities of the skull, face, jaws, and ears, as well as complex facial aesthetic and reconstructive surgery. He served two terms as Section Editor for the Pediatric Craniofacial Section of Plastic and Reconstructive Surgery. His research portfolio includes landmark contributions to facial growth and development, age-related facial structural changes, non-surgical correction of ear deformities, and the use of advanced imaging and implant materials to improve operative planning and long-term outcomes. READ the articles discussed in this podcast as well as free related content: https://bit.ly/JCFeb26Collection The views expressed by hosts and guests are their own and do not necessarily reflect the official policies or positions of ASPS.

Drs. Kat Talcott and Nita Valikodath join for a journal club episode discussion of three recent publications:‍ ‍ ‍ ‍Hemorrhagic PVD Follow-Up (https://www.aaojournal.org/article/S0161-6420(25)00791-2/fulltext)‍ ‍GLP-1 Agonists and AMD (https://www.ophthalmologyretina.org/article/S2468-6530(25)00597-4/abstract)‍ ‍Preoperative Anti-VEGF for Diabetic Vitrectomy (https://www.ophthalmologyretina.org/article/S2468-6530(25)00600-1/abstract)‍ ‍

Episode 40 of the ESCRS Eye Journal Club with Artemis Matsou, Alfredo Borgia and Victoria Till was held on 6th February 2026 The guest experts are Jose Guell and Guillermo Amescua who discuss the following paper: Bacterial Keratitis Preferred Practice Pattern

Send a textKann eine transösophageale Echokardiographie (TEE) bereits präklinisch während laufender Reanimation eingesetzt werden, ohne die CPR-Qualität zu beeinträchtigen? In dieser Episode analysieren wir die erste randomisierte kontrollierte Pilotstudie zur prähospitalen TEE bei außerklinischem Herz-Kreislauf-Stillstand (OHCA) und diskutieren Effekte auf Chest Compression Fraction, EtCO₂ sowie diagnostische und prozedurale Konsequenzen.Katzenschlager S, Kaltschmidt N, Dietrich M, et al.Prehospital transesophageal echocardiography versus conventional advanced life support in out-of-hospital cardiac arrest (PHTEE–OHCA): a randomized controlled pilot study.Critical Care. 2026;30:45.DOI: 10.1186/s13054-025-05805-w Die Qualität der Thoraxkompressionen ist ein zentraler Determinant des Outcomes beim außerklinischen Herz-Kreislauf-Stillstand (OHCA). Während transthorakale Echokardiographie (TTE) in Leitlinien empfohlen wird, kann sie zu prolongierten Hands-off-Phasen führen. Die transösophageale Echokardiographie (TEE) erlaubt dagegen Bildgebung unter laufender Kompression und könnte sowohl die Reanimationsqualität als auch die Identifikation reversibler Ursachen verbessern.In dieser randomisierten, kontrollierten Pilotstudie wurden 32 erwachsene Patient:innen mit nicht-traumatischem OHCA in einem arztbesetzten zweistufigen Rettungsdienstsystem 1:1 zu Standard-ALS oder ALS plus TEE randomisiert. Primäre Endpunkte waren Hands-off-Zeit und Chest Compression Fraction (CCF). Sekundäre Endpunkte umfassten ROSC bei Krankenhausaufnahme, Überleben bis Entlassung, neurologisches Outcome (CPC 1–2), EtCO₂-Verlauf sowie TEE-basierte diagnostische Befunde.Die mediane Hands-off-Zeit betrug in beiden Gruppen 4 Sekunden; es zeigte sich kein signifikanter Unterschied. Die CCF war jedoch signifikant höher in der TEE-Gruppe (96,2 % vs. 91,6 %; mittlere Differenz 4,6 %, 95 %-KI 2,5–6,7; p < 0,001). EtCO₂-Werte lagen ebenfalls signifikant höher in der TEE-Gruppe (+7 mmHg; 95 %-KI 4–10; p < 0,001), was auf effektivere Perfusion hinweisen könnte.In der as-treated-Analyse wurden bei 23 % der Fälle eine initial falsche Area of Maximal Compression (AMC) sowie bei 14 % eine inadäquate Kompressionstiefe identifiziert und unter TEE-Guidance korrigiert. Perikardergüsse wurden in 23 % diagnostiziert, davon 60 % hämodynamisch relevant (Tamponade). In allen eCPR-Fällen war eine Visualisierung von Führungsdrähten und Kanülenlage möglich. TEE-bedingte Komplikationen wurden nicht beobachtet.Die Studie zeigt, dass prähospitale TEE technisch machbar ist und CPR-Metriken nicht beeinträchtigt. Darüber hinaus liefert sie relevante diagnostische Informationen und ermöglicht prozedurale Guidance. Aufgrund der geringen Fallzahl ist jedoch keine Aussage zu Überlebensvorteilen möglich.

Chuck and Chris begin a new initiative working with The Journal of Hand Surgery on a quarterly journal club.  Nash and Macerena will choose the articles from the previous quarter and Chris and Chuck will review the articles and discuss practical implications.  This first episode includes discussion of the following articles from Q4 of 2025:Portney DA, Lee CP, Wolf JM, Strelzow JA, Stepan JG. A Changing Landscape in Surgical Treatment of Basilar Thumb Arthritis: Is the Rate of Denervation Increasing? J Hand Surg Am. 2025 Oct;50(10):1280.e1-1280.e8. PMID: 39918526.Earp BE, Zhang D, Benavent KA, Ostergaard PJ, Blazar PE. The Use of Telemedicine Postoperative Visits Following Carpal Tunnel and Trigger Digit Releases: A Randomized Clinical Trial. J Hand Surg Am. 2025 Dec;50(12):1431-1437. PMID: 41117725.Amen TB, Ibrahim LI, Gillinov SM, Torabian KA, Dean MC, Liimakka A, Lee SK. Glucagon-like peptide-1 Agonists and Common Hand Procedures: Perioperative and Postoperative Risks and Complications. J Hand Surg Am. 2025 Nov;50(11):1297-1303. PMID: 41055617.We are in need of a podcast intern!  We would appreciate any referrals!See www.practicelink.com/theupperhand for more information from our partner on job search and career opportunities.The Upper Hand Podcast is sponsored by Checkpoint Surgical, a provider of innovative solutions for peripheral serve surgery. To learn more, visit https://checkpointsurgical.com/.As always, thanks to @iampetermartin for the amazing introduction and concluding music.For additional links, the catalog.  Please see https://www.ortho.wustl.edu/content/Podcast-Listings/8280/The-Upper-Hand-Podcast.aspx

Send a textHow much oxygen is enough when resuscitating extremely preterm infants? This week on The Incubator Podcast, Ben and Daphna explore the TORPIDO 30/60 trial comparing 60% versus 30% FiO2 at birth. While primary outcomes were similar, babies in the 60% group needed fewer chest compressions and less epinephrine—a signal worth discussing.They examine an Indian non-inferiority study on surfactant thresholds (40% vs 30% FiO2), where waiting until 40% meant significantly fewer intubations and shorter respiratory support for the youngest babies. Ben presents compelling Melbourne data showing growth-restricted preterm infants face six-fold higher NEC risk—even with identical feeding protocols—and discusses how critical birth history gets "lost" as babies grow.Daphna tackles therapeutic hypothermia in late preterm infants, reviewing Toronto's retrospective analysis showing 34-35 weekers experience higher mortality and more brain injury compared to 36-37 weekers. As units rewrite cooling protocols, are we moving too fast on limited evidence?The episode concludes with Ben, Daphna, and Eli discussing the repeal of "sensitive locations" protections for immigration enforcement. Through the story of a mother detained while visiting her NICU baby in Chicago, they explore how these policies impact family-centered care and highlight advocacy opportunities through the Protecting Sensitive Locations Act.Current research meets real-world NICU challenges—all in one episode.Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

In this episode Dr's J and Santhosh once again review what's new in the world of medicine this time with an emphasis on love. Along the way they cover the latest olympic scandals, the believability of medical show plotlines, romantic microbiomes, how your gut influences your relationship, the effects of love on genetics and immune system, a research based rom com, the best time to induce birth,how valentine's affects heart attacks and more! So sit back and relax as we pour out our hearts over the research we adore!Further Readinghttps://pmc.ncbi.nlm.nih.gov/articles/PMC6333523/https://www.nature.com/articles/s41598-018-37298-9#Sec2https://www.ajogmfm.org/article/S2589-9333(26)00009-1/fulltexthttps://pmc.ncbi.nlm.nih.gov/articles/PMC6458105/#S1https://pmc.ncbi.nlm.nih.gov/articles/PMC8413234/#:~:text=This%20case%2Dcrossover%20analysis%20of,Year's%2C%20and%20the%20Midsummer%20holiday.Support Us spiritually, emotionally or financially here! or on ACAST+travelmedicinepodcast.comBlueSky/Mastodon/X/Instagram: @doctorjcomedy @toshyfroTikotok: DrjtoksmedicineGmail: travelmedicinepodcast@gmail.comSpotify: https://open.spotify.com/show/28uQe3cYGrTLhP6X0zyEhTPatreon: https://www.patreon.com/travelmedicinepodcast Hosted on Acast. See acast.com/privacy for more information.

Send a textIn this segment, Ben and Daphna review a retrospective study from the Hospital for Sick Children comparing outcomes of therapeutic hypothermia in late preterm (34-35 weeks) versus early term (36-37 weeks) infants. They discuss the significantly higher rates of mortality, hemodynamic instability, and hypoglycemia found in the younger cohort, known as "Group 1". The hosts explore the implications of using MRI scoring systems like the Weeke score for preterm brains and debate the ethical challenges of conducting future randomized trials as clinical practice shifts away from cooling younger babies based on emerging retrospective data.----Whole-body hypothermia in late preterm and early term infants: a retrospective analysis from a neurocritical care unit. Martinez A, Cikman G, Al Kalaf H, Wilson D, Banh B, Abdelmageed W, Beamonte Arango I, Christensen R, Branson HM, Cizmeci MN.Pediatr Res. 2026 Jan 7. doi: 10.1038/s41390-025-04701-x. Online ahead of print.PMID: 41501407Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Join us for the February edition of the Simulcast Journal Club, hosted by Vic Brazil and Jess Stokes-Parish. In this episode: Simulating clinical debriefing, psychological safety deep dive, leadership training with sim, and improving ‘code' documentation in EHRs using sim.    The February papers  Dewdney CJ, et al. Transfer of clinical debriefing from simulation to practice: exploring the barriers and enablers. Adv Simul (Lond). 2026.   Gormley G, Nestel D. Not just ‘what you say' but ‘how you say it': co-creating psychological safety through micro-communication skills in simulation-based education. J Healthc Simul. 2025 Oct 2.   Carn-Bennett E, Gan KH. Sim2Lead: A new era in leadership training for healthcare professionals. Simul Healthc. 2025;00(00):00–00.   Biesbroek S, et al. Using human factors and systems simulation to optimize the usability of a code documentation tool. Pediatr Emerg Care. 2026;00(00):000–000.     Another great month on Simulcast.  Happy listening  

The Trauma Journal Club will feature articles from experts in LC-1 Pelvic Fractures, emphasizingevidence drawn from clinical trials. Using the principles of critical appraisal, the discussions willprovide an opportunity to discuss the importance of the research question, the quality of theevidence and its limitations, its generalizability and its implications on clinical practice. Article #1: Anterior Pelvic Ring Fracture Pattern Predicts All FacultySubsequent Displacement in Lateral Compression Sacral FracturesArticle #2: Pelvic Binder Radiography Is Safe and Feasible for All FacultyQuantifying Fracture Instability in LC1 PelvisFractures: A Clinical TrialArticle #3: Patient Preferences for Operative Versus Nonoperative All FacultyTreatment of LC1 Pelvis Fracture: A Discrete Choice ExperimentArticle #4: Operative versus nonoperative treatment of All Facultystress-positive lateral compression type 1 pelvic ring injuries:A multicenter retrospective propensity-matched analysis

Send a textIn this episode of Journal Club, Ben and Daphna review a prospective cohort study from the Journal of Perinatology that examines the care of neonates following in-utero growth restriction. The hosts unpack the critical distinction between Fetal Growth Restriction (FGR) and Small for Gestational Age (SGA), highlighting how the "decay of information" in the NICU can lead clinicians to overlook early risk factors as babies grow. They discuss the study's alarming findings regarding the six-fold increased risk of Necrotizing Enterocolitis (NEC) in SGA infants and the importance of maintaining a comprehensive medical history throughout a patient's stay.----Care of neonates following in-utero growth restriction: A prospective cohort study exploring neonatal morbidity. Alda MG, Wood AG, MacDonald T, Charlton JK.J Perinatol. 2025 Sep;45(9):1219-1225. doi: 10.1038/s41372-025-02397-9. Epub 2025 Aug 21.PMID: 40841433 Free PMC article.Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

In this episode of the Award-winning PRS Journal Club Podcast, 2026 Resident Ambassadors to the PRS Editorial Board – Lucas Harrison, Christopher Kalmar, and Priyanka Naidu- and special guest, Scott P. Bartlett, MD, discuss the following articles from the February 2026 issue: "A Modified Method for Ear Projection in Auricular Reconstruction: Split-Thickness Skin Graft Combined with Retroauricular Fascia Flap for Postauricular Coverage" by Li, Feng, Hu, et al. Read the article for FREE: https://bit.ly/EarElevationRecon Special guest Dr. Scott P. Bartlett. Dr. Bartlett is one of the world's leading craniofacial surgeons and serves as Director of the Craniofacial Program and an attending surgeon in the Division of Plastic, Reconstructive, and Oral Surgery at the Children's Hospital of Philadelphia. He is also a Professor of Surgery at the Perelman School of Medicine at the University of Pennsylvania and holds the prestigious Mary Downs Endowed Chair in Pediatric Craniofacial Treatment and Research at CHOP. Dr. Bartlett's clinical expertise encompasses congenital and acquired deformities of the skull, face, jaws, and ears, as well as complex facial aesthetic and reconstructive surgery. He served two terms as Section Editor for the Pediatric Craniofacial Section of Plastic and Reconstructive Surgery. His research portfolio includes landmark contributions to facial growth and development, age-related facial structural changes, non-surgical correction of ear deformities, and the use of advanced imaging and implant materials to improve operative planning and long-term outcomes. READ the articles discussed in this podcast as well as free related content: https://bit.ly/JCFeb26Collection The views expressed by hosts and guests are their own and do not necessarily reflect the official policies or positions of ASPS.

Send a textIn this episode of Journal Club, Ben and Daphna review a non-inferiority trial from the European Journal of Pediatrics exploring surfactant administration thresholds in preterm neonates. The study, conducted in India, compares a 30% versus 40% FiO2 threshold for babies 26-32 weeks gestational age. The hosts break down the counterintuitive findings regarding respiratory support duration in younger subgroups and discuss the broader implications of using rigid FiO2 heuristics versus individualized patient assessment. They also debate how resource availability influences clinical protocols and the potential benefits of "LISA" (Less Invasive Surfactant Administration) for avoiding intubation.----Higher (40%) versus lower (30%) FiO2 threshold for surfactant administration in preterm neonates between 26 and 32 weeks of gestational age: a non-inferiority randomized controlled trial. Haq MI, Datta V, Bandyopadhyay T, Nangia S, Anand P, Murukesan VM.Eur J Pediatr. 2025 Nov 25;184(12):793. doi: 10.1007/s00431-025-06628-1.PMID: 41288797 Clinical Trial.Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Send us a textIn this episode of The Incubator, Ben and Daphna return from the Delphi Conference to dive back into Journal Club. They review the highly anticipated TORPIDO 30/60 trial published in JAMA, comparing initial oxygen concentrations of 30% versus 60% for preterm resuscitation. The hosts discuss the primary outcomes of survival and brain injury, while highlighting intriguing secondary findings regarding chest compressions and epinephrine use in the delivery room. They also share exciting updates on the Vermont Oxford Network collaboration and a new family study from the GFCNI.----Targeted Oxygen for Initial Resuscitation of Preterm Infants: The TORPIDO 30/60 Randomized Clinical Trial. Oei JL, Kirby A, Travadi J, Davis P, Wright I, Ghadge A, Yeung C, Cruz M, Keech A, Hague W, Lui K, Vento M, Gordon A, De Waal K, Chaudhari T, Hong TSL, Morris S, Kushnir A, Bonney D, Tracy M, Kumar K, Chhnia AS, Baral VR, Muniyappa P, Cheah FC, Sarnadgouda P, Rajadurai VS, Balakrishnan U, Oleti TP, Aldecoa-Bilbao V, Couce ML, Collados CT, Fernández RE, Moliner E, Ruiz Gonzalez MD, Singhal M, Agrawal G, Singh J, Pal S, Nayya S, Arora R, Amboiram P, Simes J, Tarnow-Mordi W; TORPIDO30/60 Collaborative Group.JAMA. 2025 Dec 10:e2523327. doi: 10.1001/jama.2025.23327. Online ahead of print.PMID: 41369162Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Send us a textEstamos quase chegando no Carnaval, por isso esse episódio traz a diversificação do desfile de uma escola de samba. Vem com a gente atravessar essa Sapucaí de conhecimento!1.     Hepatitis B Vaccination at Birth: Safety, Effectiveness, and Public Health Benefit - https://pubmed.ncbi.nlm.nih.gov/41639943/2.     Desaturations with or without Bradycardia are Associated with Cerebral and Abdominal Hypoxemia: Secondary Analysis of a Randomized Clinical Trial - https://pubmed.ncbi.nlm.nih.gov/41615858/3.     American Academy of Pediatrics 2022 phototherapy thresholds reduce the hospitalizations and the associated costs - https://pubmed.ncbi.nlm.nih.gov/41591975/4.     Clinical Signs Associated With Mortality and Sepsis in Young Infants A Systematic Review and Meta-Analysis - https://jamanetwork.com/journals/jamapediatrics/article-abstract/2844622 Não esqueça: você pode ter acesso aos artigos do nosso Journal Club no nosso site: https://www.the-incubator.org/podcast-1 Lembrando que o Podcast está no Instagram, @incubadora.podcast, onde a gente posta as figuras e tabelas de alguns artigos. Se estiver gostando do nosso Podcast, por favor dedique um pouquinho do seu tempo para deixar sua avaliação no seu aplicativo favorito e compartilhe com seus colegas. Isso é importante para a gente poder continuar produzindo os episódios. O nosso objetivo é democratizar a informação. Se quiser entrar em contato, nos mandar sugestões, comentários, críticas e elogios, manda um e-mail pra gente: incubadora@the-incubator.org

In this episode of the Award-winning PRS Journal Club Podcast, 2026 Resident Ambassadors to the PRS Editorial Board – Lucas Harrison, Christopher Kalmar, and Priyanka Naidu- and special guest, Scott P. Bartlett, MD, discuss the following articles from the February 2026 issue: "Anthropometrics versus Experts' Subjective Analysis of Cleft Severity and PSIO Outcomes in Unilateral Clefts: A Proposal for a New Grading" by Tanikawa, Chong, Fisher, et al. Read the article for FREE: https://bit.ly/PSIOoutcomes Special guest Dr. Scott P. Bartlett. Dr. Bartlett is one of the world's leading craniofacial surgeons and serves as Director of the Craniofacial Program and an attending surgeon in the Division of Plastic, Reconstructive, and Oral Surgery at the Children's Hospital of Philadelphia. He is also a Professor of Surgery at the Perelman School of Medicine at the University of Pennsylvania and holds the prestigious Mary Downs Endowed Chair in Pediatric Craniofacial Treatment and Research at CHOP. Dr. Bartlett's clinical expertise encompasses congenital and acquired deformities of the skull, face, jaws, and ears, as well as complex facial aesthetic and reconstructive surgery. He served two terms as Section Editor for the Pediatric Craniofacial Section of Plastic and Reconstructive Surgery. His research portfolio includes landmark contributions to facial growth and development, age-related facial structural changes, non-surgical correction of ear deformities, and the use of advanced imaging and implant materials to improve operative planning and long-term outcomes. READ the articles discussed in this podcast as well as free related content: https://bit.ly/JCFeb26Collection The views expressed by hosts and guests are their own and do not necessarily reflect the official policies or positions of ASPS.

The NACE Journal Club with Dr. Neil Skolnik, provides review and analysis of recently published journal articles important to the practice of primary care medicine. In this episode Dr. Skolnik and guests review the following publications:1. USDA Dietary Guidelines 2025-2030. Discussion by: Guest:Phillip Leiberman, MDResident Family Medicine Residency Program Jefferson Health - Abington2. The Effect of Substituting Wate for Artificially Sweetened Beverages on Glycemic and Weight Measures in People With Type 2 Diabetes: The Study of Drinks With Artificial Sweeteners (SODAS), a Randomized Trial – Diabetes Care 2025. Discussion by: Guest:Neil Skolnik, MDProfessor of Family and Community MedicineSidney  Kimmel  Medical College Thomas Jefferson UniversityAssociate Director - Family Medicine Residency ProgramJefferson Health – Abington3. Caffeinated Coffee Consumption or Abstinence to Reduce Atrial Fibrillation The DECAFRandomized Clinical Trial – JAMA 2025. Discussion by: Guest:Neil Skolnik, MDProfessor of Family and Community MedicineSidney  Kimmel  Medical College Thomas Jefferson UniversityAssociate Director - Family Medicine Residency ProgramJefferson Health – Abington4. Exercise for the Treatment of Depression. Cochrane Database of Systematic Reviews 2026 Discussion by:Guest:Aaron Sutton - Behavioral Specialist Family Medicine Residency ProgramChief Wellness Officer for Graduate Medical Education Jefferson Health – AbingtonMedical Director and Host, Neil Skolnik, MD, is an academic family physician who sees patients and teaches residents and medical students as professor of Family and Community Medicine at the Sidney Kimmel Medical College, Thomas Jefferson University and Associate Director, Family Medicine Residency Program at Abington Jefferson Health in Pennsylvania. Dr. Skolnik graduated from Emory University School of Medicine in Atlanta, Georgia, and did his residency training at Thomas Jefferson University Hospital in Philadelphia, PA. This Podcast Episode does not offer CME/CE Credit. Please visit http://naceonline.com to engage in more live and on demand CME/CE content.

In this episode Dr's J and Santhosh once again perform everybody's favorite segment journal club, this time with an emphasis on pancreatic stories. Along the way they cover medical etymology of the pancreas, the microbiome, changing cancer sensitivity with fecal transplants, giving a poop for science, lizard spit cancer scans, gila monsters and ozempic, PAC-MANN cancer detection, KRAS the undruggable gene, new targets for metastatic cells and more! So sit back and relax as we devour studies about the pancreas!Further Readinghttps://www.sjhc.london.on.ca/news-and-media/news/world-first-clinical-trial-will-study-specialized-poop-pills-to-improvehttps://www.popsci.com/science/gila-monster-spit-tumor/https://pubmed.ncbi.nlm.nih.gov/39937880/Support Us spiritually, emotionally or financially here! or on ACAST+travelmedicinepodcast.comBlueSky/Mastodon/X/Instagram: @doctorjcomedy @toshyfroTikotok: DrjtoksmedicineGmail: travelmedicinepodcast@gmail.comSpotify: https://open.spotify.com/show/28uQe3cYGrTLhP6X0zyEhTPatreon: https://www.patreon.com/travelmedicinepodcast Hosted on Acast. See acast.com/privacy for more information.

In this AJNR Fellows' Journal Club article summary, Dr. Francis Deng and Dr. Amir Khadivi discuss the article by Proner et al., "Impact of Clinical and Radiologic Factors on CTP Timing in Acute Ischemic Stroke." They discuss the authors' findings that cardiac arrhythmias and older age are independent predictors of nondiagnostic CTP exams. Specifically, these factors often lead to the truncation of reference vessel time-attenuation curves that fail to reach equilibrium within a 45-second acquisition window.

Send us a textEpisódio 71 – Journal Club 47No episódio de hoje, voltamos com assuntos variados (e polêmicos) para questionar a nossa prática e provocar a melhorar a nossa qualidade assistencial. São eles:1. Serial physical examination to reduce unnecessary antibiotic exposure in newborn infants: a population- based study - https://fn.bmj.com/content/early/2025/11/19/archdischild-2025-329639.long2. Treatment of Hypotension of Prematurity: a randomised trial - https://fn.bmj.com/content/111/1/F60.long3. Histologic chorioamnionitis and fat mass accretion in infants  born preterm - https://www.nature.com/articles/s41390-025-04413-24. The association of NICU capacity strain with neonatal mortality and morbidity - https://pmc.ncbi.nlm.nih.gov/articles/PMC12717003/ Não esqueça: você pode ter acesso aos artigos do nosso Journal Club no nosso site: https://www.the-incubator.org/podcast-1 Lembrando que o Podcast está no Instagram, @incubadora.podcast, onde a gente posta as figuras e tabelas de alguns artigos. Se estiver gostando do nosso Podcast, por favor dedique um pouquinho do seu tempo para deixar sua avaliação no seu aplicativo favorito e compartilhe com seus colegas. Isso é importante para a gente poder continuar produzindo os episódios. O nosso objetivo é democratizar a informação. Se quiser entrar em contato, nos mandar sugestões, comentários, críticas e elogios, manda um e-mail pra gente: incubadora@the-incubator.org

This month Justin and I dive deep into recent AF data and talk about dying, emotional analgesia the RSI trial and why racoon stew is on Justin's mind...

Los artículos que se tratan en el episodio de hoy están listados aquí: The neonatal SOFA score in very preterm neonates with early-onset sepsis. Tagerman M, Sahni R, Polin R. Pediatr Res. 2025 Oct 9. doi: 10.1038/s41390-025-04068-z. Online ahead of print.PMID: 41068313Systemic Postnatal Corticosteroids, Bronchopulmonary Dysplasia, and Survival Free of Cerebral Palsy. Doyle LW, Mainzer R, Cheong JLY. JAMA Pediatr. 2025 Jan 1;179(1):65-72.doi: 10.1001/jamapediatrics.2024.4575.PMID: 39556404 Bienvenidos a La Incubadora: una conversación sobre neonatología y medicina basada en evidencia. Nuestros episodios ofrecen la dosis ideal (en mg/kg) de los más recientes avances para el neonato y para las increíbles personas que forman parte de la medicina neonatal.Soy tu host, Maria Flores Cordova, MD.Este podcast está presentado por los médicos neonatólogos Dani de Luis Rosell, Elena Itriago, Carolina Michel y Juliana Castellanos.No dudes en enviarnos preguntas, comentarios o sugerencias a nuestro correo electrónico: nicupodcast@gmail.comSíguenos en nuestras redes:Twitter: @incubadorapodInstagram: @laincubadorapodcastCreado originalmente por Ben Courchia MD y Daphna Yasova Barbeau MD http://www.the-incubator.org  Bienvenidos a La Incubadora: una conversación sobre neonatología y medicina basada en evidencia. Nuestros episodios ofrecen la dosis ideal (en mg/kg) de los más recientes avances para el neonato y para las increíbles personas que forman parte de la medicina neonatal. Soy tu host, Maria Flores Cordova, MD. Este podcast está presentado por los médicos neonatólogos Dani de Luis Rosell, Elena Itriago, Carolina Michel y Juliana Castellanos. No dudes en enviarnos preguntas, comentarios o sugerencias a nuestro correo electrónico: nicupodcast@gmail.comSíguenos en nuestras redes:Twitter: @incubadorapodInstagram: @laincubadorapodcast Creado originalmente por Ben Courchia MD y Daphna Yasova Barbeau MD http://www.the-incubator.org

In this episode of the Award-winning PRS Journal Club Podcast, 2026 Resident Ambassadors to the PRS Editorial Board – Lucas Harrison, Christopher Kalmar, and Priyanka Naidu- and special guest, Shai Rozen, MD, discuss the following articles from the January 2026 issue: "Extended Sural Nerve Harvest: A Technique to Gain Additional Graft Length" by Millesi, Gates-Tanzer, Felzen, et al. Read the article for FREE: https://bit.ly/SuralNerveExt Special guest, Shai Rozen is Professor and Vice-Chairman in the Department of Plastic Surgery at the University of Texas Southwestern Medical Center and Director of the Facial Reanimation Program, specializing in treating patients with facial paralysis. He completed both general surgery and plastic surgery training at Johns Hopkins, followed by fellowships in both craniofacial and peripheral nerve surgery.  READ the articles discussed in this podcast as well as free related content: https://bit.ly/JCJan26Collection The views expressed by hosts and guests are their own and do not necessarily reflect the official policies or positions of ASPS.

Drs. Kat Talcott and Nita Valikodath join for a journal club episode discussion of three recent publications:‍ ‍ ‍ ‍Racial/Ethnic Disparities and Diabetic Retinopathy (https://www.ajo.com/article/S0002-9394(25)00593-8/abstract)‍ ‍Physician Age and Quality Outcomes (https://www.aaojournal.org/article/S0161-6420(25)00524-X/fulltext)‍ ‍IRIS Registry IOFB Study (https://www.ophthalmologyretina.org/article/S2468-6530(25)00508-1/fulltext)‍ ‍

ASOPRS Website: Click Here   In this episode of the Ocular Facial Podcast, Dr. Michelle Ting and her esteemed guests discuss significant articles from the November-December 2025 issue of OPRS. The conversation covers the role of tranexamic acid in oculoplastic surgery, the correlation between quality of life and clinical parameters in thyroid eye disease, and the potential link between air pollution and thyroid eye disease. The panelists share their insights, personal practices, and the importance of understanding patient experiences.

Send us a textCould a simple blood test help identify chronic pulmonary hypertension when echo access is limited? This week on The Incubator Podcast, Ben and Daphna explore this question and others relevant to daily NICU practice. A Toronto study examines NT-proBNP as a practical diagnostic tool in extremely preterm infants.They also examine a puzzling finding from Italy and Belgium: despite near-universal antibiotic use in neonates with HIE undergoing cooling, actual culture-positive sepsis rates are surprisingly low. What does this mean for our approach to empiric antibiotics?Ben presents Norwegian data showing that serial physical exams cut antibiotic exposure in half for term and late preterm infants—without compromising safety. Daphna follows with research connecting NICU capacity strain to patient outcomes, underscoring why adequate staffing isn't just about comfort, but about survival.The episode concludes with Ben, Daphna, and Eli discussing the recent CDC changes to Hepatitis B birth dose recommendations. With federal guidance now diverging from AAP recommendations, how do we navigate conversations with families? They explore transmission risks parents may overlook and share approaches to shared decision-making when expert opinions conflict. A full week of neonatal medicine research and real-world clinical challenges, all in one episodeSupport the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Send us a textIn this episode of Journal Club, Ben and Daphna review a retrospective cohort study from the Journal of Perinatology examining the association between NICU capacity strain and neonatal outcomes. We discuss how high census and acuity on admission day correlate with increased mortality and morbidity when adjusted for hospital and patient factors. Join us as we explore why being "slammed with admissions" is more than just a badge of honor—it's a critical safety metric for our patients.----The association of NICU capacity strain with neonatal mortality and morbidity. Salazar EG, Passarella M, Formanowski B, Rogowski J, Edwards EM, Halpern SD, Phibbs C, Lorch SA.J Perinatol. 2025 Dec;45(12):1801-1808. doi: 10.1038/s41372-025-02449-0. Epub 2025 Oct 20.PMID: 41116036 Free PMC article.Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

What types of delays do Stargardt disease patients experience when it comes to diagnosis? And what are the implications for such delays? Alexis Warren, MD, is joined by Jesse Sengillo, MD, and Sruthi Arepalli, MD, to discuss findings from a recent paper quantifying delays in diagnosis and suggesting means by which such delays could be mitigated.

Send us a textIn this episode of The Incubator Podcast, Ben and Daphna review a pivotal population-based study from Norway examining a new approach to Early-Onset Sepsis (EOS). The hosts discuss whether serial physical examinations can safely replace routine antibiotic prophylaxis in at-risk term and late-preterm infants. With antibiotic exposure often far exceeding sepsis incidence, this study offers compelling data for a "less is more" strategy. Tune in as Ben and Daphna explore the safety, efficacy, and bedside implications of substituting automatic treatment with structured clinical monitoring—and what this means for reducing unnecessary interventions in the NICU.----Serial physical examination to reduce unnecessary antibiotic exposure in newborn infants: a population-based study. Vatne A, Eriksen BHH, Bergqvist F, Fagerli I, Guthe HJT, Iversen KV, Ud Din FS, van der Weijde J, Kvaløy JT, Rettedal S.Arch Dis Child Fetal Neonatal Ed. 2025 Nov 19:fetalneonatal-2025-329639. doi: 10.1136/archdischild-2025-329639. Online ahead of print.PMID: 41260908Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

In this episode of the Award-winning PRS Journal Club Podcast, 2026 Resident Ambassadors to the PRS Editorial Board – Lucas Harrison, Christopher Kalmar, and Priyanka Naidu- and special guest, Shai Rozen, MD, discuss the following articles from the January 2026 issue: "The Natural Progression of Synkinesis" by Rail, Bhatia, Dragun, et al. Read the article for FREE: https://bit.ly/NaturalSynk Special guest, Shai Rozen is Professor and Vice-Chairman in the Department of Plastic Surgery at the University of Texas Southwestern Medical Center and Director of the Facial Reanimation Program, specializing in treating patients with facial paralysis. He completed both general surgery and plastic surgery training at Johns Hopkins, followed by fellowships in both craniofacial and peripheral nerve surgery.  READ the articles discussed in this podcast as well as free related content: https://bit.ly/JCJan26Collection The views expressed by hosts and guests are their own and do not necessarily reflect the official policies or positions of ASPS.

Send us a textIn this episode of Journal Club, Ben and Daphna dive into a multicenter retrospective study from the European Journal of Pediatrics questioning the necessity of universal empiric antibiotics in neonates undergoing therapeutic hypothermia for HIE. Comparing Italian and Belgian cohorts, the team discusses the reality of a 111 Number Needed to Treat (NNT) for a single case of culture-proven sepsis. From the diagnostic challenges of overlapping clinical markers to the fascinating "asymptote" of postnatal leukocyte trends, we explore whether it's time to shift from routine to selective antibiotic use in our most complex patients.----Antibiotic use in neonates with hypoxic-ischemic encephalopathy undergoing therapeutic hypothermia: time to rethink universal empirical treatment. De Rose DU, Piersigilli F, Auriti C, Campi F, Cortazzo V, Samaey A, Carkeek K, Martini L, Maddaloni C, Santisi A, Ronci S, Iacona G, Bersani I, Savarese I, Danhaive O, Cilio MR, Bernaschi P, Dotta A, Ronchetti MP.Eur J Pediatr. 2025 Nov 22;184(12):781. doi: 10.1007/s00431-025-06652-1.PMID: 41275063Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Send us a textIn this Journal Club episode of the Incubator Podcast, Ben Courchia and Daphna Yasova-Barbeau review a study from the Journal of Perinatology evaluating NT-proBNP as a diagnostic tool for chronic pulmonary hypertension in extremely preterm infants. The discussion walks through the clinical burden of pulmonary hypertension in babies with bronchopulmonary dysplasia, the limitations of echocardiography, and the appeal of accessible biomarkers. Using data from a SickKids Toronto cohort, the hosts unpack sensitivity, specificity, cutoff values, and real-world applicability, while exploring how NT-proBNP could support screening, risk stratification, and bedside decision-making in everyday NICU practice.----Can N-terminal pro-brain natriuretic peptide accurately diagnose chronic pulmonary hypertension among extremely low gestational age neonates: A Retrospective Cohort Study. Garcia-Gozalo M, Jain A, Weisz DE, Jasani B.J Perinatol. 2025 Nov 13. doi: 10.1038/s41372-025-02462-3. Online ahead of print.PMID: 41233504Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Featuring an interview with Dr Scott Kopetz, including the following topics:  Circulating tumor DNA (ctDNA)-guided adjuvant chemotherapy de-escalation in the treatment of Stage III colon cancer from the ctDNA-negative cohort of the DYNAMIC-III trial (0:00) Prognostic and predictive role of ctDNA in the management of Stage III colon cancer treated with celecoxib: Findings from the CALGB (Alliance)/SWOG 80702 trial (8:01) Phase III ALTAIR study comparing trifluridine/tipiracil to placebo for patients with molecular residual disease after curative resection of colorectal cancer (CRC); a methylation-based, tissue-free ctDNA test (12:51) ctDNA with locally advanced mismatch repair-deficient/microsatellite instability-high solid tumors; real-world evidence regarding ctDNA with resected CRC (17:31) CME information and select publications

Dr Scott Kopetz from The University of Texas MD Anderson Cancer Center in Houston discusses recent developments with circulating tumor DNA assays in the management of colorectal cancer. CME information and select publications here.

Send us a textThis week on The Incubator Podcast, Ben and Daphna review several recent studies in neonatal care. They start with a JAMA trial comparing expectant versus active PDA management in preterm infants, noting a survival signal favoring expectant care and discussing how this fits within current practice. They then review outcomes of 21-week gestation infants from the University of Iowa, focusing on resuscitation strategies and survival at the limits of viability.The conversation continues with the ICAF trial, examining whether extending caffeine therapy through 41 weeks postmenstrual age meaningfully reduces intermittent hypoxia and for which infants this may matter. A large national cohort study on antenatal corticosteroids between 21 and 24 weeks gestation is also discussed, highlighting practice variation and implications for counseling.The episode closes with a Neo News segment on legal liability in the NICU following a recent $32 million NEC settlement. Ben, Daphna, and Eli consider informed consent around nutritional care and how evolving legal pressures may influence communication and clinical decision making.This compilation brings together research and policy discussions from the week in a single long-form episode.Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Send us a textIn this Journal Club episode, Ben and Daphna review a large national cohort study examining the association between antenatal corticosteroid exposure and survival in extremely preterm infants born between 21 and 24 weeks' gestation. They discuss biologic plausibility, practice variation, and the challenges of interpreting retrospective data, while focusing on how these findings may inform counseling and shared decision-making at the margins of viability.----The Effects of Antenatal Corticosteroids on Extremely Premature Neonates Born between 21 and 24 Weeks. Yao R, Tritch N, Vedhanayagam K, Ali N, Reimche-Vu H, Gedestad I, Karageuzian S, Contag S.Am J Perinatol. 2025 Nov 6. doi: 10.1055/a-2722-8107. Online ahead of print. PMID: 41086871Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Send us a textBen and Daphna review the ICAF randomized clinical trial evaluating extended caffeine therapy in preterm infants and its impact on intermittent hypoxia through 41 weeks postmenstrual age. They discuss the study design, oximetry outcomes across multiple saturation thresholds, inflammatory biomarkers including TNF-α, and clinically relevant safety signals such as oxygen restart rates, length of stay, and weight gain. The conversation focuses on what intermittent hypoxia may mean for ongoing risk, and whether a targeted subgroup of infants might benefit from extending caffeine beyond traditional stopping points.----Intermittent hypoxia and caffeine in infants born preterm: the ICAF Randomized Clinical Trial. Eichenwald E, Corwin M, McEntire B, Knoblach S, Limperopoulos C, Kapse K, Kerr S, Heeren TC, Ikponmwonba C, Hunt CE; ICAF Study Group.Arch Dis Child Fetal Neonatal Ed. 2025 Nov 24:fetalneonatal-2025-329230. doi: 10.1136/archdischild-2025-329230. Online ahead of print.PMID: 41285561Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

In this episode of the Award-winning PRS Journal Club Podcast, 2026 Resident Ambassadors to the PRS Editorial Board – Lucas Harrison, Christopher Kalmar, and Priyanka Naidu- and special guest, Shai Rozen, MD, discuss the following articles from the January 2026 issue: "The Efficacy of Flap Debulking after Facial Reanimation Surgery to Enhance Facial Symmetry" by Weiss, Fricke, Hohenstein, et al. Read the article for FREE: https://bit.ly/FlapDebulk Special guest, Shai Rozen is Professor and Vice-Chairman in the Department of Plastic Surgery at the University of Texas Southwestern Medical Center and Director of the Facial Reanimation Program, specializing in treating patients with facial paralysis. He completed both general surgery and plastic surgery training at Johns Hopkins, followed by fellowships in both craniofacial and peripheral nerve surgery.  READ the articles discussed in this podcast as well as free related content: https://bit.ly/JCJan26Collection The views expressed by hosts and guests are their own and do not necessarily reflect the official policies or positions of ASPS.

Send us a textIn this Journal Club episode, Ben and Daphna review a salient study from JAMA Network Open examining outcomes of infants born at 21 weeks' gestation at the University of Iowa. They walk through resuscitation practices, early physiologic challenges, survival trends, and short-term developmental outcomes, while placing the data in the broader context of shifting limits of viability. The discussion highlights both cautious optimism and the many unanswered questions that remain as neonatology continues to push the boundaries of what is possible.----Outcomes of Infants Born at 21 Weeks' Gestational Age. Hyland RM, Mat HD, Boly TJ, Thomas BJ, Stanford AH, Harmon HM, Bermick JR, Davila RC, Colaizy TT, Dagle JM, Klein JM, Greiner AL, Bell EF, McNamara PJ; University of Iowa Neonatology Program.JAMA Netw Open. 2025 Dec 1;8(12):e2548211. doi:10.1001/jamanetworkopen.2025.48211.PMID: 41385227 Free PMC article.Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Featuring an interview with Dr Scott Kopetz, including the following topics: Circulating tumor DNA (ctDNA)-based molecular residual disease (MRD) and survival among patients with resectable colorectal cancer (CRC) in the CIRCULATE-Japan GALAXY trial (0:00) ctDNA for detection of MRD in patients with CRC in the BESPOKE CRC and INTERCEPT trials (3:11) Clinical utility of including ctDNA monitoring in standard CRC surveillance (11:11) ctDNA analysis guiding adjuvant therapy for CRC in the DYNAMIC and CIRCULATE-North America trials (15:52) CME information and select publications

Send us a textIn this Journal Club episode, Ben and Daphna review a major randomized clinical trial published in JAMA comparing expectant management with active pharmacologic treatment of patent ductus arteriosus in preterm infants. They walk through the trial design, inclusion criteria, and outcomes, highlighting the unexpected survival difference favoring expectant management despite similar rates of bronchopulmonary dysplasia. The discussion explores the implications for bedside decision-making, the limitations of PDA-focused strategies, and the need for a more physiologic, patient-centered approach to ductal management in extremely preterm infants.----Expectant Management vs Medication for Patent Ductus Arteriosus in Preterm Infants: The PDA Randomized Clinical Trial. Laughon MM, Thomas SM, Watterberg KL, Kennedy KA, Keszler M, Ambalavanan N, Davis AS, Slaughter JL, Guillet R, Colaizy TT, Cotten CM, Dhawan MA, Bose CL, Talbert J, Smucny S, Benitz WE, Rysavy MA, Ohls RK, Baserga MC, DeMauro SB, Jaleel M, Jackson WM, Carlo WA, Puopolo KM, Hibbs AM, Katheria A, Sánchez PJ, D'Angio CT, Patel RM, Johnson BA, Chock VY, Bhatt AJ, Merhar SL, Moore R, Laptook AR, Ghavam S, Fuller J, Vyas-Read S, Kicklighter SD, Steinbrekera B, Anderson K, Reynolds AM, Wyckoff MH, Montoya C, Das A, Do B, Chang S, Higgins RD, Walsh MC; Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network.JAMA. 2025 Dec 9:e2523330. doi: 10.1001/jama.2025.23330. Online ahead of print.PMID: 41364689Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Get access to more than 200 episodes of my premium podcast (The Aliquot) when you sign up as a FoundMyFitness Premium Member Download my "How to Train According to the Experts" guide One minute of vigorous exercise may be worth up to ten minutes of "moderate" cardio for extending lifespan and preventing chronic disease. In this Journal Club episode, Rhonda Patrick, PhD and endurance athlete Brady Holmer dissect a new Nature Communications study of more than 70,000 adults showing that vigorous intensity is roughly 4–10x more potent than moderate activity for reducing all-cause mortality, cardiovascular events, type 2 diabetes, and cancer outcomes—far beyond the long-standing 1:2 rule embedded in global exercise guidelines. Timestamps: (00:00) Introduction (07:01) What exactly is the 1:2 rule for exercise intensity? (08:18) Calorie burn vs. longevity—origins of the 1:2 rule (11:15) What counts as 'vigorous' exercise, really? (13:35) Where the exercise guidelines fall short (14:19) Can your wearable predict disease risk years in advance? (20:11) Is vigorous activity easier to achieve than people think? (22:47) How researchers avoided the 'healthy user bias' (23:59) Health equivalence ratio—a better way to measure exercise benefits? (25:45) Is vigorous exercise truly 4–10x more effective? (29:55) Can one vigorous minute match an hour of gentle walking? (32:02) Why vigorous activity—not gentle—offers dose-dependent benefits (33:50) Is vigorous exercise 5x better at preventing heart attacks & strokes? (34:24) Why vigorous activity stands out for cancer prevention (34:59) Does zone 2 qualify as vigorous exercise? (36:11) Dose-response comparison—vigorous vs. moderate vs. light activity (37:22) Is vigorous exercise the secret to younger arteries? (43:15) Why aging hearts need intensity (46:09) Can vigorous exercise halt your VO₂ max decline? (47:26) Why moderate exercise alone might not improve VO₂ max (49:21) Is vigorous exercise 10x more powerful at preventing diabetes? (55:48) Mitochondrial biogenesis—why intensity is essential (58:40) Can you directly measure mitochondrial health? (1:00:57) Does vigorous exercise kill circulating tumor cells? (1:07:15) Why vigorous intensity triggers beneficial hormone changes (1:08:05) Can vigorous activity protect older adults from falls? (1:12:36) Does vigorous exercise combat inflammation? (1:14:29) Is high-intensity training the key to a younger brain? (1:16:01) Is vigorous exercise more powerful than we realized? (1:17:50) Can the benefits of vigorous exercise fit into a pill? (1:19:08) How small doses of intensity might extend your lifespan (1:23:15) Do short bursts of vigorous movement match full workouts? (1:27:26) Why your wearable might undervalue short vigorous bouts (1:30:06) Can planned micro-workouts replace traditional gym sessions? (1:35:10) Why exercise guidelines urgently need updating (1:46:35) Does light activity still offer real benefits? (1:49:04) Is vigorous exercise safe for older adults? (1:53:28) Are high-intensity workouts detrimental to female hormones? (1:58:02) Safe vigorous exercise options—even with chronic illness (1:59:05) The 80/20 rule for balancing intensity and recovery (2:01:30) Inside Brady's routine—how much vigorous exercise is optimal? (2:05:17) Can vigorous activity boost kids' brainpower (and grades)? (2:08:14) Are we significantly underestimating vigorous exercise benefits? (2:10:03) Why chasing steps isn't the answer Show notes are available by clicking here Watch this episode on YouTube