Podcasts about Journal club

Send us Fan MailPhototherapy duration, jaundice and UTIs, extended CPAP, and The Pitt. A full week on the Incubator Journal Club.Ben opens with a nationwide Swedish cohort study from JAMA Network Open examining phototherapy duration in nearly 5,000 very preterm infants. Longer phototherapy was not significantly associated with late neonatal mortality, but six to seven days was associated with significantly higher rates of severe neonatal morbidity. With 95% of the cohort receiving phototherapy, Ben and Daphna question how much evidence actually supports the near-universal practice.Daphna follows with a retrospective study from Istanbul showing that 31% of term and near-term neonates hospitalized for unexplained hyperbilirubinemia had culture-proven UTIs, with pathological renal ultrasound findings independently associated with a 4.6-fold increased odds of UTI.Ben then reviews the extended CPAP secondary analysis by Mamidi and McEvoy, showing that two additional weeks of bubble CPAP reduced intermittent hypoxemia episodes from 151.7 to 57.6 compared to discontinued CPAP.Daphna closes with the NEOASP five-day UTI treatment guideline from Nationwide Children's Hospital, where a structured stewardship approach yielded a 1% failure rate.Ben and Eli close the week reflecting on The Pitt and what it reveals about the broken realities of American healthcare.Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.Enjoy!

Este episódio não estava no meu bingo card há uma semana, mas sabes quando acontece algo tão forte que sentes que não podes ignorar? Foi o que me aconteceu. Tenho mais perguntas do que respostas neste momento. Neste episódio vulnerável partilho contigo um pouco do processo e dos meus próximos passos profissionais. Obrigada por estares aqui!Acede aos bundles dos nossos workshops aqui:https://app.notion.com/p/Siddhi-37cd28ed411080348f3ee65d9e0652e4Alguma dúvida escreve-nos para info@siddhi.pt Com amor, Jasmim

Send us Fan MailIs five days of antibiotics enough to treat a urinary tract infection in a NICU infant? In this Journal Club episode, Ben and Daphna review a single-center study from Nationwide Children's Hospital examining adherence and safety of a five-day antibiotic treatment guideline for culture and urinalysis-proven UTIs in the NICU. Among 77 infants with 93 bacterial UTIs, the five-day course was associated with a 1% failure rate, defined as reinitiation of antibiotics within seven days for the same organism. The episode also explores the potential role of enteral antibiotic therapy and what shorter treatment courses could mean for babies still weeks away from discharge.----Urinary tract infection in the neonatal intensive care unit. Magers J, Burton A, Prusakov P, White NO, Miller RR, Moraille R, Theile AR, Sánchez PJ; Nationwide Children's Hospital Neonatal Antimicrobial Stewardship Program (NEO-ASP).J Perinatol. 2026 May;46(5):754-760. doi: 10.1038/s41372-026-02690-1. Epub 2026 Apr 29.PMID: 42056240 Free PMC article.Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.Enjoy!

Send us Fan MailWhat happens to intermittent hypoxemia when you keep a stable preterm infant on CPAP for two extra weeks? In this Journal Club episode, Ben and Daphna review a secondary analysis from the Journal of Pediatrics by Mamidi and McEvoy. Among 95 infants randomized to either two additional weeks of bubble CPAP on room air or discontinued CPAP, those in the extended CPAP group experienced significantly fewer intermittent hypoxemia episodes (57.6 versus 151.7), higher baseline saturations, and greater functional residual capacity. The episode also touches on the practical implications for units navigating oral feeding protocols alongside extended CPAP.----Extended Continuous Positive Airway Pressure in Infants Born Preterm Decreases Intermittent Hypoxemia: A Secondary Analysis of a Randomized Controlled Trial. Mamidi RR, Go MDA, Harris J, Olson M, Milner K, Tepper RS, Morris C, Park B, Schelonka R, MacDonald KD, McEvoy CT.J Pediatr. 2026 May 25:115165. doi: 10.1016/j.jpeds.2026.115165. Online ahead of print.PMID: 42190903Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.Enjoy!

In this episode of the Award-winning PRS Journal Club Podcast, 2026 Resident Ambassadors to the PRS Editorial Board – Lucas Harrison, Christopher Kalmar, and Priyanka Naidu- and special guest, Devinder Singh, MD, discuss the following articles from the June 2026 issue:   "The Double Intradermal Continuous Suture Technique for the Round Block in Periareolar Mastopexy" by Pelle-Ceravolo, Angelini, et al.   Read the article for FREE: https://bit.ly/RoundBlock_Mastopexy   Devinder Singh, MD, is the Chief of the Division of Plastic and Reconstructive Surgery, Program Director, and a Professor of Surgery (and secondary professor of dermatology) at the University of Miami Miller School of Medicine.    READ the articles discussed in this podcast as well as free related content: https://bit.ly/JCJune26Collection   The views expressed by hosts and guests are their own and do not necessarily reflect the official policies or positions of ASPS.

Send us Fan MailIn this Journal Club episode, Daphna reviews a retrospective cohort study from Istanbul examining clinical, laboratory, and ultrasound factors associated with UTI in neonates hospitalized for unexplained hyperbilirubinemia. Among 96 term and near-term infants, 31% had culture-proven UTIs, a striking prevalence. Pathological renal ultrasound findings were independently associated with UTI, with affected neonates 4.6 times more likely to have a concurrent infection. Notably, standard laboratory markers including CRP and white blood cell count failed to distinguish UTI-positive from UTI-negative infants. The findings prompt a practical question: should urine culture be part of the routine workup for neonatal hyperbilirubinemia?----Renal ultrasonography findings are associated with urinary tract infection in neonates with asymptomatic hyperbilirubinemia. Sarı EE, Salihoğlu Ö.J Perinatol. 2026 Apr 13. doi: 10.1038/s41372-026-02686-x. Online ahead of print.PMID: 41975209Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.Enjoy!

Todos queremos muita coisa ao mesmo tempo, muitas vezes coisas opostas até. Porque queremos coisas opostas? Como encontrar o caminho no meio? Como é que isso atrapalha ou não, o processo de criação de realidade?Estas e outras questões neste episódio. Entra no Journal Club:https://journal-club.ptVem fazer o workshop gratuito: journaling sem tretashttps://olasiddhi.kit.com/01b7262803

Send us Fan MailIn this Journal Club episode, Ben and Daphna review a nationwide Swedish cohort study examining the association between phototherapy duration and neonatal outcomes in very preterm infants (22 to 31 weeks). The study's primary outcome, late neonatal mortality on days 8 to 27, was not significantly associated with phototherapy duration. However, longer phototherapy exposure was associated with increased odds of severe neonatal morbidity, including IVH and BPD, in infants born at 26 to 31 weeks. The findings prompt an important conversation about the near-universal use of phototherapy in preterm neonates and whether current practice warrants reassessment.----Phototherapy, Morbidity, and Mortality in Very Preterm Newborns. Deschmann E, Håkansson S, Söderling J, Norman M.JAMA Netw Open. 2026 May 1;9(5):e2614107. doi: 10.1001/jamanetworkopen.2026.14107.PMID: 42166159 Free PMC article.Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.Enjoy!

Send us Fan MailBem-vindos ao Episódio 80! Neste Journal Club, percorremos quatro estudos recentes que ampliam nossa compreensão sobre o cuidado ao prematuro — da sala de parto à vida adulta jovem.1.     Transition to Adulthood for Extremely Preterm Survivors - https://publications.aap.org/pediatrics/article/153/1/e2022060119/196245/Transition-to-Adulthood-for-Extremely-Preterm?autologincheck=redirected2.     Growth and safety evaluation in very low birth weight infants receiving an exclusive human milk diet: a phase III randomized control trial in Japan  - https://www.nature.com/articles/s41372-026-02695-w3.     Cerebral Oximetry–Guided Treatment and Cerebral Oxygenation in Extremely Preterm Infants: A Randomized Clinical Trial - https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2844666?utm_campaign=articlePDF&utm_medium=articlePDFlink&utm_source=articlePDF&utm_content=jamanetworkopen.2025.57620#google_vignette4.     Apgar Score Plus Umbilical Artery pH and Adverse Neonatal Outcomes in Very Preterm Infants  - https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2844714?utm_campaign=articlePDF&utm_medium=articlePDFlink&utm_source=articlePDF&utm_content=jamanetworkopen.2025.57913Quatro perguntas diferentes, uma mesma direção: cuidar melhor, com mais precisão e mais evidência. Não esqueça: você  pode ter acesso aos artigos do nosso Journal Club no nosso site: https://www.the-incubator.org/podcast-1Lembrando que o Podcast está no Instagram, @incubadora.podcast, onde a gente posta as figuras e tabelas de alguns artigos. Se estiver gostando do nosso Podcast, por favor dedique um pouquinho do seu tempo para deixar sua avaliação no seu aplicativo favorito e compartilhe com seus colegas. Isso é importante para a gente poder continuar produzindo os episódios. O nosso objetivo é democratizar a informação.Se quiser entrar em contato, nos mandar sugestões, comentários, críticas e elogios, manda um e-mail pra gente: incubadora@the-incubator.orgEvidência, cuidado e contexto brasileiro - esse é o nosso roteiro.

Featuring perspectives from Prof Thomas Powles, including the following topics: Circulating tumor DNA (ctDNA) analyses with adjuvant nivolumab for MIBC in the CheckMate 274 study (0:00) Use of ctDNA to guide response-adapted bladder preservation for patients with MIBC (2:27) ctDNA response-adapted treatment de-escalation for patients with metastatic urothelial carcinoma: The CT-READ trial (10:26) Emerging data and studies regarding urinary tumor DNA (18:04) CME information and select publications

Moderator: Ashley Levack, MD, MASFaculty Presenters: Roman Natoli, MD, PhD, Gregory Schimizzi, MD, PhDArticle #1: Skin Antisepsis before Surgical Fixation of Extremity Fractures Article #2: Oral vs Intravenous Antibiotics for Fracture-Related InfectionsArticle #3: High Nonunion and Amputations Rates with Either Early TBDIntramedullary Nail Removal or Retention for Tibial ShaftFracture-Related Infections

In this episode of the Award-winning PRS Journal Club Podcast, 2026 Resident Ambassadors to the PRS Editorial Board – Lucas Harrison, Christopher Kalmar, and Priyanka Naidu- and special guest, Devinder Singh, MD, discuss the following articles from the June 2026 issue:   "The Inframammary Fold Effacement Flap for Strong Fold Breast Augmentation Patients" by Hoffman and Tavakoli.   Read the article for FREE: https://bit.ly/IMF_Effacement   Devinder Singh, MD, is the Chief of the Division of Plastic and Reconstructive Surgery, Program Director, and a Professor of Surgery (and secondary professor of dermatology) at the University of Miami Miller School of Medicine.    READ the articles discussed in this podcast as well as free related content: https://bit.ly/JCJune26Collection   The views expressed by hosts and guests are their own and do not necessarily reflect the official policies or positions of ASPS.

The NACE Journal Club with Dr. Neil Skolnik, provides review and analysis of recently published journal articles important to the practice of primary care medicine. In this episode Dr. Skolnik and guests review the following publications:1. Orforglipron for maintenance of body weight reduction  - Nature Medicine2026. Discussion by:Guest:Joe Gonella, MD Resident - Abington Family Medicine Residency Program Jefferson Health2. Tirzepatide for maintenance of bodyweight reduction in people with obesity in the USA (SURMOUNT-MAINTAIN) Lancet 2026.  Discussion by: Guest:Neil Skolnik, MDProfessor of Family and Community MedicineSidney  Kimmel  Medical College Thomas Jefferson UniversityAssociate Director - Family Medicine Residency ProgramJefferson Health – Abington3. Survival and Recurrence with GLP-1 Receptor Agonists in Breast Cancer" – JAMA Network Open Discussion by:Guest:Neil Skolnik, MDProfessor of Family and Community MedicineSidney  Kimmel  Medical College Thomas Jefferson UniversityAssociate Director - Family Medicine Residency ProgramJefferson Health – Abington4. In Vivo Base Editing of PCSK9 with VERVE-102 for Hypercholesterolemia.   NEJM 2026 Discussion by:Guest:Alex Sauer, MD Resident - Abington Family Medicine Residency ProgramJefferson HealthMedical Director and Host, Neil Skolnik, MD, is an academic family physician who sees patients and teaches residents and medical students as professor of Family and Community Medicine at the Sidney Kimmel Medical College, Thomas Jefferson University and Associate Director, Family Medicine Residency Program at Abington Jefferson Health in Pennsylvania. Dr. Skolnik graduated from Emory University School of Medicine in Atlanta, Georgia, and did his residency training at Thomas Jefferson University Hospital in Philadelphia, PA. This Podcast Episode does not offer CME/CE Credit. Please visit  http://naceonline.com to engage in more live and on demand CME/CE content.

O Journal Club está no mundo e neste episódio eu conto-te tudo o que esteve por trás desta criação. Começou com um desejo de eu estar a fazer junk journaling com outras mulheres, até à criação de um espaço seguro e profundo para crescermos juntas. O Journal Club é muita coisa, é comunidade, criatividade, profundidade e leveza.Vem daí, esperamos por ti. Até ao dia 16/06 podes trazer uma amiga gratuitamente para o JC. Sabe mais aqui:https://www.instagram.com/p/DZCu48njTwT/?img_index=5Entra no Journal Clubhttps://journal-club.pt/

Send us Fan MailOpioid withdrawal dosing, intranasal breast milk, human milk fortification in Japan, neonatal dysphagia, and vaccine policy. A full week on the Incubator Journal Club.Ben opens with the Optimized NOW trial in JAMA: symptom-based dosing reduced time to medical readiness for discharge by nearly two and a half days in NOWS infants managed with Eat Sleep Console, and allowed 65% of pharmacologically treated infants to avoid scheduled opioids entirely.Daphna reviews a small RCT out of Turkey showing improved cerebral oxygenation and favorable vital sign trends after intranasal breast milk administration in preterm infants, adding to the growing tolerability data for this intervention.Ben then covers the JASMINE trial, a Phase 3 RCT in Japan showing significantly better weight gain velocity with an exclusive human milk diet in very low birth weight infants.Daphna closes with a retrospective cohort study on FEES-confirmed dysphagia in preterm infants. Of those who met criteria for evaluation, every single one had laryngeal penetration and 57% were aspirating.Ben and Eli close the week on the quiet dismantling of vaccine infrastructure in the US and what it means for the populations in your NICU.Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.Enjoy!

Moderator​: Lucas Marchand, MD, BSFaculty: Zachary Working, MD, Patrick Kellam, MD, Graham DeKeyser, MDArticle #1: Type III Open Tibia Fractures: Immediate Antibiotic All-FacultyProphylaxis Minimizes Infection Article #2: Allgöwer-Donati Versus Vertical Mattress Suture All-FacultyTechnique Impact on Perfusion in Ankle FractureSurgery: A Randomized Clinical Trial Using Intraoperative AngiographyArticle #3: Efficacy of Topical Antibiotic Powder Application in the All-FacultyEmergency Department on Reducing Deep Fracture-RelatedInfection in Type III Open Lower Extremity Fractures: A Multicenter StudyArticle #4: Infection and Nonunion Rates in Open Fractures: Description All-Facultyof 6,042 Fractures from the FLOW and PREP-IT Trials ​​

Send us Fan MailHow often are we missing dysphagia in our most vulnerable NICU patients? In this episode of Journal Club, Daphna reviews a retrospective cohort study from the Journal of Perinatology examining the incidence and risk factors of dysphagia confirmed by flexible endoscopic evaluation of swallowing (FEES) in very preterm and very low birth weight infants. Among infants showing persistent feeding difficulties at 38 weeks post-menstrual age, laryngeal penetration was detected in all infants who underwent FEES, and tracheal aspiration in nearly 60%. Ben and Daphna discuss whether we are naming dysphagia for what it is, whether earlier instrumental assessment could change outcomes, and what it means for families to finally understand why their baby is struggling to feed.----Incidence and factors associated with dysphagia in infants born very preterm or very low birth weight. Reynolds J, Suterwala M, Desai S, Chiruvolu A.J Perinatol. 2026 Apr 29. doi: 10.1038/s41372-026-02701-1. Online ahead of print.PMID: 42056238Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.Enjoy!

Send us Fan MailJapan has some of the best survival rates for extremely preterm infants in the world, yet feeding practices there look very different from what many of us are used to. In this episode of Journal Club, Ben reviews the JASMINE trial, a multicenter phase three randomized controlled trial evaluating an exclusive human milk diet compared to a standard cow milk-based diet in very low birth weight infants in Japan. Infants on an exclusive human milk diet gained weight significantly faster, reached full feeds six days sooner, and had fewer antibiotic days. Ben then sits down with first author Professor Katsumi Mizuno and Dr. Melinda Elliott, CMO of Prolacta Bioscience, to discuss the backstory and broader implications of this landmark trial.---Growth and safety evaluation in very low birth weight infants receiving an exclusive human milk diet: a phase III randomized control trial in Japan. Mizuno K, Miyazawa T, Kondo U, Nishikubo T, Yamamoto Y, Nakano Y, Hiroma T, Ikeda K, Murase M, Jimi H, Hokuto I, Miyata M.J Perinatol. 2026 Apr 27. doi: 10.1038/s41372-026-02695-w. Online ahead of print.PMID: 42045666Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.Enjoy!

Interview conducted on March 11, 2026, by Dr Neil Love, including the following topics: Circulating tumor DNA (ctDNA)-guided adjuvant therapy with atezolizumab for muscle-invasive bladder cancer (MIBC) (0:00) Use of ctDNA in guiding systemic treatment selection for patients with urothelial bladder cancer (10:03) ctDNA analyses with perioperative durvalumab for MIBC in the Phase III NIAGARA study (16:51) New research advances in the monitoring and management of urothelial bladder cancer (22:21) CME information and select publications  

Send us Fan MailCould putting a few drops of breast milk in a preterm infant's nose actually improve cerebral oxygenation? In this episode of Journal Club, Daphna reviews a randomized controlled trial from the European Journal of Pediatrics investigating the physiologic effects of intranasal expressed breast milk (EBM) administration in preterm infants. The study found that infants receiving 0.2 mL of fresh breast milk intranasally three times daily showed significantly higher cerebral oxygenation levels, along with more favorable trends in heart rate and respiratory rate, compared to controls. While time to full oral feeding and length of hospital stay were unchanged, the safety data is reassuring. Ben and Daphna discuss what outcomes we should even be measuring, and whether the evidence is already good enough to just do it.----Effect of intranasal breast milk administration on cerebral oxygenation, vital signs, and transition time to full oral feeding in preterm infants: a randomized controlled study. Yücel A, Küçükoğlu S, Konak M.Eur J Pediatr. 2026 Apr 16;185(5):272. doi: 10.1007/s00431-026-06922-6.PMID: 41986747Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.Enjoy!

Join CardioNerds EP Council Chair Dr. Naima Maqsood and Episode Lead Dr. Sukriti Banthiya as they discuss the results of the International Collaborative LBBAP Study (I-CLAS) with expert faculty Dr. Theofanie Mela and Dr. Pugazhendhi Vijayraman. Audio editing by CardioNerds academy intern, Grace Qiu. The International Collaborative LBBAP Study (I-CLAS) evaluated clinical outcomes between biventricular pacing (BVP) and left bundle branch area pacing (LBBAP) in patients with left ventricular ejection fraction (LVEF) ≤50% undergoing cardiac resynchronization therapy. Between January 2018 and June 2023, 2,579 patients were enrolled across 18 centers. The primary composite outcome was defined as all-cause mortality or heart failure hospitalization. LBBAP demonstrated a shorter paced QRS duration and was associated with a lower risk of primary composite outcome and heart failure hospitalization. No significant difference was observed in all-cause mortality. Additionally, procedural complications were lower with LBBAP. This episode was planned in collaboration with  Heart Rhythm TV with mentorship from Dr. Daniel Alyesh and Dr. Mehak Dhande.  Enjoy this Circulation 2022 Paths to Discovery article to learn about the CardioNerds story, mission, and values. US Cardiology Review is now the official journal of CardioNerds! Submit your manuscript here. CardioNerds Journal Club PageCardioNerds Episode PageCardioNerds AcademyCardionerds Healy Honor Roll CardioNerds Journal ClubSubscribe to The Heartbeat Newsletter!Check out CardioNerds SWAG!Become a CardioNerds Patron!

Send us Fan MailOne infant is diagnosed with neonatal opioid withdrawal syndrome every 27 minutes, and rates are rising. In this episode of Journal Club, Ben and Daphna review the Optimized NOW randomized clinical trial, a landmark multicenter study published in JAMA. The trial compared symptom-based dosing,  a single opioid dose given when a withdrawal threshold is met against the traditional scheduled opioid taper in infants managed with Eat Sleep Console. The results are striking: symptom-based dosing reduced time to medical readiness for discharge by nearly two and a half days, and 65% of pharmacologically treated infants avoided scheduled opioid dosing entirely. Could this be the evidence-based approach that finally reshapes how we treat NOWS pharmacologically?----Symptom-Based Dosing for Neonatal Opioid Withdrawal: The OPTimize NOW Randomized Clinical Trial. Devlin LA et al HEAL Evaluation of Limited Pharmacotherapies for Neonatal Opioid Withdrawal Syndrome (HELP for NOWS) Consortium.JAMA. 2026 Apr 25:e265782. doi: 10.1001/jama.2026.5782. Online ahead of print. PMID: 42033722Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.Enjoy!

Chuck and Chris continue the initiative working with The Journal of Hand Surgery on a quarterly journal club.  Nash and Macerena choose the articles from the previous quarter and Chris and Chuck review the articles and discuss practical implications.  See articles below.In addition, we discuss a case of possible pronator syndrome together with carpal tunnel syndrome including debate on the role of nerve studies, physical examination, and ultrasound.1) Rames JD, Emanuels AF, Tunaboylu MF, Moran SL. A 40-Year Retrospective Evaluation of Vascularized Bone Grafting for Kienböck Disease. J Hand Surg Am. 2026 Jan;51(1):13.e1-13.e9. doi: 10.1016/j.jhsa.2025.07.025. Epub 2025 Aug 29. PMID: 40879579.2) Suzuki T, Kiyota Y, Matsumura N, Sato K, Nakamura M, Iwamoto T. Anatomical Reconstruction of the Terminal Tendon and Lateral Band for Severe Chronic Tendon Mallet Injury. J Hand Surg Am. 2026 Jan;51(1):92.e1-92.e7. doi: 10.1016/j.jhsa.2025.04.025. Epub 2025 Jun 21. PMID: 40542795.3) Lee C, Shin S, Fraipont G, Hung V, McGarry MH, Lee TQ. Dermal Allograft Augmentation With Proximal Row Carpectomy: A Biomechanical Study. J Hand Surg Am. 2026 Feb;51(2):143-152. doi: 10.1016/j.jhsa.2025.05.006. Epub 2025 Jul 4. PMID: 40613810.4) Jaarsma EH, Ring D, Tonn MD, Brinkman N. Do Patients Older Than 40 Years with Work Claims for Unilateral Wrist Symptoms Have Symmetric, Bilateral MRI Signal Changes That Do Not Correspond with Symptoms? J Hand Surg Am. 2026 Mar;51(3):313-320. doi: 10.1016/j.jhsa.2025.11.012. Epub 2026 Jan 29. PMID: 41609546.5) Pohl NB, Brush PL, Parson JP, Fitzgerald P, Charlton A, Beredjiklian PK, Fletcher DJ. Incidence and Predictors of Subsequent Triggering Requiring Treatment After Trigger Finger Release. J Hand Surg Am. 2026 Feb;51(2):203.e1-203.e8. doi: 10.1016/j.jhsa.2025.02.009. Epub 2025 Apr 9. PMID: 40202483.We are in need of a podcast intern!  We would appreciate any referrals!See www.practicelink.com/theupperhand for more information from our partner on job search and career opportunities.The Upper Hand Podcast is sponsored by Checkpoint Surgical, a provider of innovative solutions for peripheral serve surgery. To learn more, visit https://checkpointsurgical.com/.As always, thanks to @iampetermartin for the amazing introduction and concluding music.For additional links, the catalog.  Please see https://www.ortho.wustl.edu/content/Podcast-Listings/8280/The-Upper-Hand-Podcast.aspx

Send us Fan MailO que você oferece nas primeiras semanas importa — e muitoQuatro estudos. Quatro perguntas que todo neonatologista e pediatra já enfrentou na prática. Voltamos a apresentar os artigos do livro 50 Estudos que Todo Neonatologista Deve Conhecer, dessa vez com os artigos que revolucionaram a nutrição neonatal.Qual fórmula dar a um prematuro quando o leite materno não está disponível? Promover o aleitamento de forma estruturada realmente muda desfechos clínicos? Leite doado é superior à fórmula para prematuros extremos? E como manejar a hipoglicemia neonatal sem separar mãe e bebê?Neste episódio da Incubadora, discutimos os ensaios de Lucas et al. no BMJ, o PROBIT no JAMA, o DoMINO no JAMA e o Sugar Babies no Lancet — estudos que, juntos, constroem um argumento difícil de ignorar: decisões tomadas nas primeiras horas e semanas de vida deixam marcas que aparecem no pulmão, no cérebro e no desenvolvimento anos mais tarde.1.     Randomised trial of early diet in preterm babies and later intelligence quotient  - https://pubmed.ncbi.nlm.nih.gov/9831573/2.     Promotion of Breastfeeding Intervention Trial (PROBIT) A Randomized Trial in the Republic of Belarus - https://pubmed.ncbi.nlm.nih.gov/11242425/3.     Effect of Supplemental Donor Human Milk Compared With Preterm Formula on Neurodevelopment of Very Low-Birth-Weight Infants at 18 Months A Randomized Clinical Trial - https://pubmed.ncbi.nlm.nih.gov/27825008/4.     Dextrose gel for neonatal hypoglycaemia (the Sugar Babies Study): a randomised, double-blind, placebo-controlled trial - https://pubmed.ncbi.nlm.nih.gov/24075361/Evidência, cuidado e contexto brasileiro — esse é o nosso roteiro. Não esqueça: você  pode ter acesso aos artigos do nosso Journal Club no nosso site: https://www.the-incubator.org/podcast-1Lembrando que o Podcast está no Instagram, @incubadora.podcast, onde a gente posta as figuras e tabelas de alguns artigos. Se estiver gostando do nosso Podcast, por favor dedique um pouquinho do seu tempo para deixar sua avaliação no seu aplicativo favorito e compartilhe com seus colegas. Isso é importante para a gente poder continuar produzindo os episódios. O nosso objetivo é democratizar a informação.Se quiser entrar em contato, nos mandar sugestões, comentários, críticas e elogios, manda um e-mail pra gente: incubadora@the-incubator.orgEvidência, cuidado e contexto brasileiro - esse é o nosso roteiro.

In this episode of the Award-winning PRS Journal Club Podcast, 2026 Resident Ambassadors to the PRS Editorial Board – Lucas Harrison, Christopher Kalmar, and Priyanka Naidu- and special guest, Andrea L. Pusic, MD, discuss the following articles from the May 2026 issue: "Cost of Care and Surgical Outcomes between Direct-to-Implant and Staged Tissue Expander Breast Reconstruction" by Chakraborty, Bouhadana, Bernstein et al. Read the article for FREE: https://bit.ly/DTI_TE_Comparison Dr. Andrea L. Pusic is our special guest. She serves as Chief of Plastic and Reconstructive Surgery at Brigham and Women's Hospital, Director of Patient-Reported Outcomes, and the Joseph Murray Professor of Surgery at Harvard Medical School. Dr. Pusic also holds a Master of Public Health from Johns Hopkins University. She completed her general surgery residency at Dalhousie University, followed by a plastic surgery residency at McGill University and a microsurgery fellowship at Memorial Sloan Kettering Cancer Center. Her clinical practice focuses on breast reconstruction and aesthetic breast surgery, including both autologous tissue reconstruction and implant-based techniques, with a strong emphasis on individualized, patient-centered care and quality-of-life outcomes. An internationally recognized leader in patient-reported outcomes research, Dr. Pusic has authored more than 200 publications. She developed the BREAST-Q, a widely used instrument for measuring patient satisfaction and quality of life after breast surgery. She also co-led the NCI-funded Mastectomy Reconstruction Outcomes Consortium, a multi-institutional collaboration across 11 centers studying patient perspectives on breast reconstruction. Dr. Pusic now leads the PROVE Center, where she advances the use of patient-reported outcomes to improve surgical quality, patient experience, and healthcare value. READ the articles discussed in this podcast as well as free related content: https://bit.ly/JCMay26Collection

Send us Fan MailIn this episode of The Oncology Journal Club, the team cover one of the most talked-about pancreatic cancer papers of the year, unpacking the promising early results for daraxonrasib in previously treated RAS-mutated pancreatic cancer and the science behind new RAS(ON) therapeutics. The team also discuss a fascinating phase II study of single-cycle neoadjuvant pembrolizumab in MMR-deficient colon cancer, new recommendations from the Prostate Cancer Working Group 4 and why the terminology we use in prostate cancer matters.Along the way, there's discussion of Bob Marley's acral melanoma, multidisciplinary lung cancer meetings, androgen receptor-positive TNBC, HER2-mutant lung cancer and whether oxybutynin could help men experiencing androgen deprivation-related hot flushes.The Oncology Journal Club Podcast is hosted by Professor Craig Underhill, Dr Kate Clarke and Professor Chris Jackson, and proudly produced by The Oncology NetworkVisit oncologynetwork.com.au for Show Notes, to send us Voice Notes and more information. 

Send us Fan MailCerebral oxygenation, staffing economics, delivery room scoring, neurodevelopmental prognostication, and public health — a full week on the Incubator Journal Club.Ben walks through the NIRTURE trial, a single-device RCT testing cerebral oximetry-guided care in infants born under 29 weeks. The intervention dramatically reduced the burden of cerebral hypoxia and hyperoxia compared to standard care. Secondary clinical outcomes were neutral and neurodevelopmental follow-up is still pending. The question of whether stabilizing cerebral oxygenation actually moves the needle for these babies remains unanswered.Daphna covers a brief communication from the Journal of Perinatology on what happens to billing and productivity when NICUs shift to 24-hour in-house attending coverage. Clinical FTE went up, work RVUs went down — and the reason is counterintuitive. Attendings present overnight were weaning babies faster. Better care, less revenue. The coding system was not built to capture that.Ben then pairs the 5-minute Apgar with umbilical artery pH in very preterm infants using EPICE cohort data. When both are low, risk is highest. When they compete, the Apgar wins.Daphna rounds out Journal Club with a systematic review showing that combining EEG and brain MRI outperforms either tool alone for neurodevelopmental prognostication in preterm infants.The week closes with Ben and Eli on the sweeping domestic and international public health funding cuts — and what they mean for the vulnerable populations in your NICU.Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.Enjoy!

Los artículos que se tratan en el episodio de hoy están listados aquí: 1. PMID: 41991672Association between route of furosemide administration and diuretic response in very preterm infants with bronchopulmonary dysplasia.Bamat NA, Huber M, Morris H, Nelin TD, Downes KJ, O'Brien AB, Laskin BL, Jensen EA, DeMauro SB, Eichenwald EC, Lorch SA.J Perinatol. 2026 Apr 16. doi: 10.1038/s41372-026-02662-5. Online ahead of print.2. PMID: 41921774Nutritional Management of Infants with Severe Bronchopulmonary Dysplasia (sBPD) During Acute Infection.Thompsen K, Murthy K, Robinson DT, Baptiste S, Li J, Falciglia GH.J Pediatr. 2026 Mar 30:115086. doi: 10.1016/j.jpeds.2026.115086. Online ahead of print.3. PMID: 41731043Effects of higher caffeine dosing on rates of bronchopulmonary dysplasia and neurodevelopmental outcomes.Fleishaker S, Kazmi SH, Mavrogiannis N, Street H, Ravuri H, Moinuddin T, Pierce K, Verma S.J Perinatol. 2026 Feb 23. doi: 10.1038/s41372-026-02593-1. Online ahead of print. Bienvenidos a La Incubadora: una conversación sobre neonatología y medicina basada en evidencia. Nuestros episodios ofrecen la dosis ideal (en mg/kg) de los más recientes avances para el neonato y para las increíbles personas que forman parte de la medicina neonatal. Soy tu host, Maria Flores Cordova, MD. Este podcast está presentado por los médicos neonatólogos Dani de Luis Rosell, Elena Itriago, Carolina Michel y Juliana Castellanos. No dudes en enviarnos preguntas, comentarios o sugerencias a nuestro correo electrónico: nicupodcast@gmail.comSíguenos en nuestras redes:Twitter: @incubadorapodInstagram: @laincubadorapodcastCreado originalmente por Ben Courchia MD y Daphna Yasova Barbeau MD http://www.the-incubator.org

When do symptomatic vitreous floaters warrant surgery, and when is observation sufficient? In this episode of New Retina Radio Journal Club with VBS, host Kyle Kovacs, MD, joins Matthew Starr, MD, and Neda Valikodath, MD, to review a major study on vision-degrading myodesopsias from vitreous floaters. They then debate the risks and value of limited refractive vitrectomy for select patients in real-world settings, and review their protocols for patients who present with floaters. 

Send us Fan MailIn this episode of Journal Club, we wrap up a marathon recording session with a deep dive into the world of neonatal neuroprognostication. Daphna reviews a systematic review and meta-analysis from Pediatric Neurology that evaluates whether combining EEG and MRI provides better answers for families of preterm infants. While MRI remains a powerful tool for structural assessment, the data suggests that adding the functional insights of EEG significantly boosts specificity, particularly when predicting severe neurodevelopmental outcomes. We discuss the importance of timing these studies and the clinical value of sleep-wake cycling as a developmental milestone at the bedside.----Combined Use of Electroencephalography and Magnetic Resonance Imaging in the Prognostication of Neurodevelopmental Outcomes in Preterm Infants - A Systematic Review and Meta-Analysis. Forrest CD, Biagioni T, Liley HG, Lai MM, Colditz PB, Ware RS, Boyd RN, Roberts JA.Pediatr Neurol. 2026 Feb;175:116-129. doi: 10.1016/j.pediatrneurol.2025.11.005. Epub 2025 Nov 13.PMID: 41337899 Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.Enjoy!

Send us Fan MailBen kicks things off with a major career update before we dive into a critical study from JAMA Network Open. We explore the predictive value of the five minute Apgar score when combined with umbilical artery pH in very preterm infants. While the Apgar score was originally designed for term babies, this analysis of the EPICE cohort reveals its enduring utility even in the smallest patients. We discuss how these two measures interact, which one "wins" when they conflict, and why the clinician assessment remains a powerful predictor of mortality and severe morbidity in the NICU.----Apgar Score Plus Umbilical Artery pH and Adverse Neonatal Outcomes in Very Preterm Infants. Ehrhardt H, Behboodi S, Maier RF, Aubert AM, Ådén U, Staude B, Draper ES, Gudmundsdottir A, Siljehav V, Varendi H, Weber T, Zemlin M, Zeitlin J; EPICE/SHIPS Research Group.JAMA Netw Open. 2026 Feb 2;9(2):e2557913.Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.Enjoy!

In this episode of the Award-winning PRS Journal Club Podcast, 2026 Resident Ambassadors to the PRS Editorial Board – Lucas Harrison, Christopher Kalmar, and Priyanka Naidu- and special guest, Andrea L. Pusic, MD, discuss the following articles from the May 2026 issue: "Single versus Multiple Perforator Flaps in Autologous Breast Reconstruction: A Regression Analysis of Clinical Outcomes and Financial Metrics" by DeVito, Ke, Wen, et al. Read the article for FREE: https://bit.ly/MutliperfAutoBreast Dr. Andrea L. Pusic is our special guest. She serves as Chief of Plastic and Reconstructive Surgery at Brigham and Women's Hospital, Director of Patient-Reported Outcomes, and the Joseph Murray Professor of Surgery at Harvard Medical School. Dr. Pusic also holds a Master of Public Health from Johns Hopkins University. She completed her general surgery residency at Dalhousie University, followed by a plastic surgery residency at McGill University and a microsurgery fellowship at Memorial Sloan Kettering Cancer Center. Her clinical practice focuses on breast reconstruction and aesthetic breast surgery, including both autologous tissue reconstruction and implant-based techniques, with a strong emphasis on individualized, patient-centered care and quality-of-life outcomes. An internationally recognized leader in patient-reported outcomes research, Dr. Pusic has authored more than 200 publications. She developed the BREAST-Q, a widely used instrument for measuring patient satisfaction and quality of life after breast surgery. She also co-led the NCI-funded Mastectomy Reconstruction Outcomes Consortium, a multi-institutional collaboration across 11 centers studying patient perspectives on breast reconstruction. Dr. Pusic now leads the PROVE Center, where she advances the use of patient-reported outcomes to improve surgical quality, patient experience, and healthcare value. READ the articles discussed in this podcast as well as free related content: https://bit.ly/JCMay26Collection

Send us Fan MailIs your NICU considering the shift to 24 hour in house attending coverage? In this episode of Journal Club, we explore a provocative brief communication from the Journal of Perinatology. Ben and Daphna discuss the impact of moving from home call to on site presence at UC Davis. While the change was intended to improve patient care, the data reveals a surprising 15 percent decrease in work RVUs. We examine how proactive weaning and bedside presence might actually lower billing levels under current CPT codes. Are we being penalized for doing the right thing for our patients?----From on-call to on-site: the impact of 24-hour in-house neonatology on billing patterns and physician productivity. Donohue L, Lakshminrusimha S.J Perinatol. 2026 Feb;46(2):289-292. doi: 10.1038/s41372-025-02530-8. Epub 2026 Jan 5.PMID: 41490931 Free PMC article. No abstract available.Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.Enjoy!

Send us Fan MailIn this episode of Journal Club, Ben and Daphna dive into the results of the NIRTURE trial, recently published in JAMA Network Open. Building on the lessons of SafeBoosC 3 , the NIRTURE investigators aimed to reduce the burden of cerebral hypoxia and hyperoxia in extremely preterm infants using a standardized NIRS guided treatment protocol. While the study showed a dramatic improvement in maintaining cerebral normoxia, driven largely by a reduction in hyperoxia , the clinical outcomes before discharge remained neutral. Join us as we discuss whether regional oximetry is a must have bedside tool or just another data point in search of a clear clinical benefit.  ----Cerebral Oximetry-Guided Treatment and Cerebral Oxygenation in Extremely Preterm Infants: A Randomized Clinical Trial. Jani PR, Goyen TA, Balegar KK, Maheshwari R, Saito-Benz M, Schindler T, Moore J, Merhi M, Cruz M, Song Y, McDonagh H, Luig M, Tracy M, D'Cruz D, Perdomo A, Morakeas S, Dasireddy V, Culcer M, Shingde V, Bennington K, Michalowski J, Fucek A, Querim J, Stevens S, Santanelli J, Elhindi J, Gloss B, Halliday R, Shah D, Popat H.JAMA Netw Open. 2026 Feb 2;9(2):e2557620. Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.Enjoy!

Join us for the May edition of the Simulcast Journal Club, hosted by Vic Brazil and Ben Symon. In this episode: Eye tracking for simulator validation, augmented realty to help in cardiac arrest, moulage safety practice and reflections on process versus outcome evaluations.     The May papers  Tzamaras et al. Tracking success: exploring the application of eye tracking for simulator validation in the clinical and simulated environments. Human Factors in Healthcare. 2025;7  Cheng A, et al. Impact of an augmented reality-based decision support system on teamwork, leadership, provider workload and cognitive load during simulated cardiac arrest: a simulation-based randomized controlled trial. Advances in Simulation. 2026. doi:10.1186/s41077-026-00444-9.  Stokes-Parish J, et al. Moulage safety practice around the world: a framework for best practice. Advances in Simulation. 2026. doi:10.1186/s41077-026-00438-7.  Schram AL. Simulation process, outcomes, and what I failed to see. Simulation in Healthcare. 2026;21(2):139-140. doi:10.1097/SIH.0000000000000912.    Happy listening     Don't forget – Simulation Reconnect in Singapore July 16/17  Registration open now - HERE    

Send us Fan MailNeste episódio de A Incubadora, mergulhamos em três estudos recentes que colocam o intestino do prematuro no centro da discussão científica — cada um por um ângulo diferente, cada um com uma contribuição única para quem cuida desses bebês todos os dias.O primeiro artigo nos leva para o território da neuroproteção. Outcomes after intranasal human milk therapy in preterm infants with intraventricular hemorrhage - https://pubmed.ncbi.nlm.nih.gov/39384614/O segundo artigo muda de órgão — mas não de urgência. Early regional splanchnic oxygen saturation and the development of necrotizing enterocolitis in preterm infants 28–32 weeks of gestation - https://www.sciencedirect.com/science/article/pii/S037837822600099XO terceiro artigo é o maior dos três — e talvez o de maior impacto imediato para a prática clínica. Live biotherapeutic product IBP-9414 (L. reuteri) in very low birth weight infants: the Connection Study - https://www.google.com/search?client=safari&rls=en&q=Live+biotherapeutic+product+IBP-9414+(L.+reuteri)+in+very+low+birth+weight+infants%3A+the+Connection+Study&ie=UTF-8&oe=UTF-8Três estudos. Três delineamentos diferentes. Três contribuições para um mesmo desafio: melhorar a sobrevida e a qualidade de vida dos bebês mais vulneráveis que chegam às nossas UTINs.Como sempre, nossa missão é trazer a ciência para perto de quem está à beira do leito — com rigor, com contexto e com o olhar atento às realidades do cuidado neonatal brasileiro. Não esqueça: você  pode ter acesso aos artigos do nosso Journal Club no nosso site: https://www.the-incubator.org/podcast-1Lembrando que o Podcast está no Instagram, @incubadora.podcast, onde a gente posta as figuras e tabelas de alguns artigos. Se estiver gostando do nosso Podcast, por favor dedique um pouquinho do seu tempo para deixar sua avaliação no seu aplicativo favorito e compartilhe com seus colegas. Isso é importante para a gente poder continuar produzindo os episódios. O nosso objetivo é democratizar a informação.Se quiser entrar em contato, nos mandar sugestões, comentários, críticas e elogios, manda um e-mail pra gente: incubadora@the-incubator.org

Carepoint Journal Club is a quarterly series with discussions about a medical topic, brought to you by Carepoint's Emergency Physicians.

In this episode of the Award-winning PRS Journal Club Podcast, 2026 Resident Ambassadors to the PRS Editorial Board – Lucas Harrison, Christopher Kalmar, and Priyanka Naidu- and special guest, Andrea L. Pusic, MD, discuss the following articles from the May 2026 issue: "Prepectoral versus Subpectoral Implant-Based Breast Reconstruction: Evaluating the Shift" by Cordray, Khan, Voytik, et al. Read the article for FREE: https://bit.ly/PrePecVSSubPec Dr. Andrea L. Pusic is our special guest. She serves as Chief of Plastic and Reconstructive Surgery at Brigham and Women's Hospital, Director of Patient-Reported Outcomes, and the Joseph Murray Professor of Surgery at Harvard Medical School. Dr. Pusic also holds a Master of Public Health from Johns Hopkins University. She completed her general surgery residency at Dalhousie University, followed by a plastic surgery residency at McGill University and a microsurgery fellowship at Memorial Sloan Kettering Cancer Center. Her clinical practice focuses on breast reconstruction and aesthetic breast surgery, including both autologous tissue reconstruction and implant-based techniques, with a strong emphasis on individualized, patient-centered care and quality-of-life outcomes. An internationally recognized leader in patient-reported outcomes research, Dr. Pusic has authored more than 200 publications. She developed the BREAST-Q, a widely used instrument for measuring patient satisfaction and quality of life after breast surgery. She also co-led the NCI-funded Mastectomy Reconstruction Outcomes Consortium, a multi-institutional collaboration across 11 centers studying patient perspectives on breast reconstruction. Dr. Pusic now leads the PROVE Center, where she advances the use of patient-reported outcomes to improve surgical quality, patient experience, and healthcare value. READ the articles discussed in this podcast as well as free related content: https://bit.ly/JCMay26Collection

This month we tackle some big PE papers. We have a stuff from bomb blasts to avalanche victims and some of the dull stuff in between. 

The NACE Journal Club with Dr. Neil Skolnik, provides review and analysis of recently published journal articles important to the practice of primary care medicine. In this episode Dr. Skolnik and guests review the following publications:1. Evolocumab to Reduce First Major Cardiovascular Events in Patients Without Known Significant Atherosclerosis and With Diabetes Results From the VESALIUS-CV Trial. JAMA 2026. Discussion by:Guest:Jessica Stieritz, MDResident - Abington Family Medicine Residency Program Jefferson Health2. A treat-to-target strategy versus symptom-driven management of gout in the Netherlands (GO TEST Overture): a multicentre, open-label, pragmatic, superiority, randomized controlled trial. Lancet Rheumatology 2026. Discussion by:Guest:Neil Skolnik, MDProfessor of Family and Community MedicineSidney  Kimmel  Medical College Thomas Jefferson UniversityAssociate Director - Family Medicine Residency ProgramJefferson Health – Abington3. Oral Nirmatrelvir–Ritonavir for Covid-19 in Higher-Risk Outpatients. NEJM 2026 Discussion by: Guest:Steven Leonard, MD Resident - Abington Family Medicine Residency Program Jefferson HealthMedical Director and Host, Neil Skolnik, MD, is an academic family physician who sees patients and teaches residents and medical students as professor of Family and Community Medicine at the Sidney Kimmel Medical College, Thomas Jefferson University and Associate Director, Family Medicine Residency Program at Abington Jefferson Health in Pennsylvania. Dr. Skolnik graduated from Emory University School of Medicine in Atlanta, Georgia, and did his residency training at Thomas Jefferson University Hospital in Philadelphia, PA. This Podcast Episode does not offer CME/CE Credit. Please visit  http://naceonline.com to engage in more live and on demand CME/CE content.

In this episode Dr's J and Santhosh once again perform a roundup of what's new in the world of medicine with an emphasis on gut research! Along the way they cover a decrease in national obesity, snake ozempic, reptile racism, bad jokes, athlete microbiomes, bacterial doping, microplastic absorbing diets, milk frogs and more! SO sit back and relax as we gobble up some articles on gut medicine and research!Further Readinghttps://jamanetwork.com/journals/jama-health-forum/fullarticle/2827712?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=121324https://www.nature.com/articles/s42255-026-01485-0https://www.nature.com/articles/s41591-019-0485-4https://www.sciencedirect.com/science/article/abs/pii/S0960852426003159Support Us spiritually, emotionally or financially here! or on ACAST+travelmedicinepodcast.comBlueSky/Mastodon/X/Instagram: @doctorjcomedy @toshyfroTikotok: DrjtoksmedicineGmail: travelmedicinepodcast@gmail.comSpotify: https://open.spotify.com/show/28uQe3cYGrTLhP6X0zyEhTPatreon: https://www.patreon.com/travelmedicinepodcast Hosted on Acast. See acast.com/privacy for more information.

Send us Fan MailBem-vindos ao episódio 77 do A Incubadora, o podcast quinzenal que aproxima a ciência de quem vive a neonatologia todos os dias — à beira do leito, na residência ou nos livros.Hoje seguimos com mais um capítulo do nosso Especial "50 Estudos que Todo Neonatologista Deve Conhecer", e o tema é o pulmão do prematuro — palco de algumas das decisões mais críticas e dos avanços mais transformadores da nossa especialidade.Neste episódio, mergulhamos em três artigos fundamentais:Prevention of Neonatal Respiratory Distress Syndrome by Tracheal Instillation of Surfactant — https://pubmed.ncbi.nlm.nih.gov/3895150/  o ensaio clínico randomizado que abriu caminho para uma das intervenções mais icônicas da neonatologia moderna e mudou para sempre a forma como encaramos a SDR.Long-Term Effects of Caffeine Therapy for Apnea of Prematurity — https://www.nejm.org/doi/full/10.1056/NEJMoa073679 um clássico que vai além da apneia: os dados de longo prazo que todo neonatologista precisa conhecer antes de prescrever — ou deixar de prescrever — a cafeína.Early CPAP versus Surfactant in Extremely Preterm Infants — https://pubmed.ncbi.nlm.nih.gov/20472939/ o estudo que colocou em xeque protocolos estabelecidos e acendeu o debate sobre qual deve ser a primeira linha de suporte respiratório nos extremos da prematuridade.Três artigos. Três marcos. Uma conversa essencial para quem cuida dos menores pacientes.Seja você estudante, residente ou especialista, este episódio foi feito para você. Nos acompanhe, compartilhe com sua equipe e deixe sua avaliação — isso nos ajuda a democratizar ainda mais o conhecimento em neonatologia.Bons estudos e boa escuta! Não esqueça: você  pode ter acesso aos artigos do nosso Journal Club no nosso site: https://www.the-incubator.org/podcast-1Lembrando que o Podcast está no Instagram, @incubadora.podcast, onde a gente posta as figuras e tabelas de alguns artigos. Se estiver gostando do nosso Podcast, por favor dedique um pouquinho do seu tempo para deixar sua avaliação no seu aplicativo favorito e compartilhe com seus colegas. Isso é importante para a gente poder continuar produzindo os episódios. O nosso objetivo é democratizar a informação.Se quiser entrar em contato, nos mandar sugestões, comentários, críticas e elogios, manda um e-mail pra gente: incubadora@the-incubator.org

So Much JENergy is on the farm, y'all… and this one is special

Send us Fan MailThe AAP has weighed in on therapeutic hypothermia for HIE, and Daphna walks through the clinical report in full. The core eligibility criteria haven't moved — but the edges have gotten more nuanced. Late initiation, the 35-week zone, mild HIE, sentinel events, MRI timing, and feeding during cooling are all addressed.Also this week: a prospective pilot from Australia tests whether adding bedside ultrasound to plain radiography improves surgical risk stratification in NEC. The X-ray-only model couldn't separate the clusters. The combined model produced a more than six-fold difference in odds of surgery — complex ascites, absent peristalsis, and abnormal bowel perfusion did the heavy lifting.Daphna then covers F-NeoBright, a small but compelling feasibility study testing intranasal fresh breast milk in infants with moderate to severe HIE. Ten babies, high adherence, no safety signals, and parents administering doses at home.Ben rounds out Journal Club with the two-year follow-up of the CALI trial examining outcomes after early caffeine plus LISA versus CPAP alone. Mortality trended toward LISA. The statistics didn't get there — but the direction held.The week closes with Ben and Eli on the Guttmacher Institute study linking restrictive abortion laws to higher maternal mortality across two decades of US data.Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.Enjoy!

Featuring an interview with Dr Natalie Vokes, including the following topics: Perioperative minimal residual disease (MRD) detected by circulating tumor DNA (ctDNA) testing in patients with lung cancer (0:00) Ohara S et al. Clinical significance of perioperative MRD detected by ctDNA in patients with lung cancer with a long follow-up data: An exploratory study. JTO Clin Res Rep 2024;6(3):100762. Abstract Masuda K et al. MRDSEEKER (JCOG2111A): A prospective study to evaluate MRD and its association with prognosis in curative-intent NSCLC. World Conference on Lung Cancer 2025;Abstract P3.18.04.  Zhou C et al. IMpower010: Biomarkers of disease-free survival in a phase 3 study of atezolizumab vs best supportive care after adjuvant chemotherapy in stage IB-IIIA NSCLC. ESMO IO 2021;Abstract 2O. MRD analysis of adjuvant therapy with osimertinib for resected EGFR-mutated Stage IB to IIIA non-small cell lung cancer (NSCLC) (8:28) Herbst RS et al. Molecular residual disease analysis of adjuvant osimertinib in resected EGFR-mutated stage IB-IIIA non-small-cell lung cancer. Nat Med 2025;31(6):1958-68. Abstract MRD analyses of perioperative chemoimmunotherapy for resected NSCLC (15:12) Forde PM et al. Overall survival with neoadjuvant nivolumab plus chemotherapy in lung cancer. N Engl J Med 2025;393(8):741-52. Abstract  ctDNA dynamics in advanced NSCLC treated with immunotherapy (20:56) Vokes NI et al. Circulating tumor DNA (ctDNA) dynamics and survival outcomes in patients (pts) with advanced non-small cell lung cancer (aNSCLC) and high (>50%) programmed cell death ligand 1 (PD-L1) expression, randomized to cemiplimab (cemi) vs chemotherapy (chemo). ASCO 2023;Abstract 9022. Anagnostou V et al. ctDNA response after pembrolizumab in non-small cell lung cancer: Phase 2 adaptive trial results. Nat Med 2023;29(10):2559-69. Abstract Anagnostou V et al. A biomarker-directed, multi-center phase II/III study of ctDNA molecular response adaptive immuno-chemotherapy in patients with non-small cell lung cancer (BR.36). ASCO 2025;Abstract TPS8669. CME information and select publications

Send us Fan MailIn this Journal Club episode, Ben reviews a secondary analysis of the CALI trial, published in JAMA Network Open, examining two-year neurodevelopmental and pulmonary outcomes in preterm infants who received early caffeine combined with LISA versus caffeine and CPAP alone. Building on the original CALI trial's finding that early caffeine prior to LISA reduced intubation rates and BPD, this follow-up asks the next logical question: does that early advantage translate into better long-term outcomes? Ben walks through the Bayley scores, gross motor function, ASQ-3, M-CHAT, and pulmonary outcomes — and delivers a reassuring if not statistically significant picture. Tune in for a deep dive into the evidence behind one of neonatology's most debated respiratory strategies!----Two-Year Outcomes of Less Invasive Surfactant Administration Among Preterm Neonates: A Secondary Analysis of a Randomized Clinical Trial. Dorner RA, Morales A, Banerji A, Uy C, Ines F, Finer N, Vaucher Y, Katheria AC.JAMA Netw Open. 2026 Mar 2;9(3):e263852. doi: 10.1001/jamanetworkopen.2026.3852.PMID: 41915392Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.Enjoy!

Send us Fan MailIn this Journal Club episode, Daphna presents the F-NeoBright trial — a pilot feasibility and safety study out of Hungary exploring intranasal fresh breast milk administration in neonates with moderate to severe HIE undergoing therapeutic hypothermia. With so few adjunct therapies available beyond cooling, the idea of harnessing breast milk's rich bioactive components — including neurotrophic growth factors, cytokines, and multipotent stem cells — to support the developing brain is both compelling and refreshingly low-risk. Daphna walks us through the protocol, the feasibility outcomes, and why 100% of approached families consented, including those who had never planned to breastfeed. Sometimes the simplest intervention really is the right one!----F-NEO-BRIGHT: feasibility and safety of intranasal fresh breast milk in neonatal encephalopathy. Tarjanyi E, Jermendy A, Szabo M, Brandt FA, Szasz B, Nyilas N, Meder U.Pediatr Res. 2026 Mar 3. doi: 10.1038/s41390-026-04847-2. Online ahead of print.PMID: 41776367Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.Enjoy!

In this episode of the Award-winning PRS Journal Club Podcast, 2026 Resident Ambassadors to the PRS Editorial Board – Lucas Harrison, Christopher Kalmar, and Priyanka Naidu- and special guest, Jordan W. Swanson, MD, discuss the following articles from the April 2026 issue: "A Comparison of Surgical Techniques for Macroglossia in Beckwith-Wiedemann Syndrome" by Romeo, Lenz, George, et al. Read the article for FREE: https://bit.ly/BeckwithSyndrome  Special guest Dr. Jordan Swanson is the Linton Whitaker Endowed Chair of Craniofacial Surgery at the Children's Hospital of Philadelphia and an associate professor of surgery at the Perelman School of Medicine at the University of Pennsylvania. He specializes in the care of patients with cleft lip and palate, craniosynostosis, and other craniofacial conditions, as well as adult craniofacial and aesthetic surgery. His work in global partnerships with teams in low- and middle-income countries has spanned more than a decade, including collaboration with the Nicaraguan Ministry of Health, where he helped build a joint, comprehensive cleft and craniofacial program. He has also led initiatives to expand access to high-quality surgical care in low-resource settings through his clinical practice, research, and global health leadership. Dr. Swanson advances surgical innovation, education, and care delivery across diverse healthcare contexts. READ the articles discussed in this podcast as well as free related content: https://bit.ly/JCApril26Collection The views expressed by hosts and guests are their own and do not necessarily reflect the official policies or positions of ASPS.

Send us Fan MailIn this Journal Club episode, Ben takes the lead and reviews a prospective cohort pilot study from the Archives of Disease in Childhood examining whether combining abdominal ultrasound with plain radiography can improve surgical risk stratification in neonates with suspected NEC. With mortality remaining as high as 20–40% and diagnosis still heavily reliant on clinical judgment, the stakes couldn't be higher. Ben walks through the study's unsupervised clustering approach, explaining how adding ultrasound data to X-ray findings produced a more than six-fold difference in the odds of surgery between risk groups — something X-ray alone simply couldn't achieve. Tune in to hear why dynamic ultrasound features like peristalsis, ascites, and bowel perfusion may be the missing piece in your NEC diagnostic toolkit!----Combining abdominal ultrasound and radiography for surgical risk stratification in necrotising enterocolitis: a prospective cohort pilot study. Priyadarshi A, Angiti R, Chabra S, McAdams R, Webb A, Badawi N, Hinder MK, Tracy MB.Arch Dis Child Fetal Neonatal Ed. 2026 Mar 5:fetalneonatal-2025-329960. doi: 10.1136/archdischild-2025-329960. Online ahead of print.Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.Enjoy!

Send us Fan MailIn this Journal Club episode, Ben and Daphna dive into the American Academy of Pediatrics' February Clinical Report on Therapeutic Hypothermia for Neonatal Hypoxic-Ischemic Encephalopathy. Daphna, who presented this paper at the Florida Neonatal Neurologic Network, walks us through the key action statements — from the established 33.5°C target temperature to the more nuanced discussions around late cooling (6–24 hours), gestational age eligibility at 35 weeks, and the controversial question of cooling mild HIE. They also cover optimal MRI timing post-rewarming, continuous EEG monitoring, early enteral feeds during cooling, and the growing evidence supporting the "cool cuddle." A must-listen for anyone navigating the evolving landscape of HIE management!----Therapeutic Hypothermia for Neonatal Hypoxic-Ischemic Encephalopathy: Clinical Report. Zanelli SA, Wusthoff CJ, Lucke AM, Kaufman DA; Committee on Fetus and Newborn; Section on Neurology.Pediatrics. 2026 Feb 1;157(2):e2025073627. doi: 10.1542/peds.2025-073627.PMID: 41581784 Review.Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.Enjoy!