Podcasts about Dopamine

Four chemicals, produced by your brain, serve as a master switch for nearly everything you think, do, and feel. In no small way, they also control our lives. But, all too often, instead of harnessing them to fuel amazing experiences and outcomes, we are controlled by them. Today, we learn how to take back control and harness them for good.Our guide is TJ Power, lead neuroscientist at the DOSE Lab and the author of The DOSE Effect. His research investigates how modern sedentary, digitally saturated lifestyles are reshaping the brain chemicals that govern how we feel, connect, focus, and recover from stress. He has delivered live experiences to over 75,000 people at institutions including Oxford University, Amazon, and the NHS.His DOSE framework centers on four chemicals: Dopamine, Oxytocin, Serotonin, and Endorphins. These chemicals evolved over hundreds of thousands of years for a very different experience of life. One with more movement, more connection, more sunlight, more sustained effort, and far less of what TJ calls dopamine land, the scroll-and-reward loop that phones have engineered into our days.In this conversation, you will explore:Why dopamine is not the reward chemical you were taught it was, and why the phone has hijacked the system that was supposed to motivate youThe difference between dopamine and oxytocin, and why TJ believes we are pursuing the wrong chemical as a speciesHow 90% of your serotonin is manufactured in your gut, and what ultra-processed food is actually doing to your moodWhy stress evolved to be released through physical movement, and why sitting still with your problems makes them worseThe 20 free behaviors from The DOSE Effect that recalibrate all four chemicals without cost, pills, or a major life overhaulIf you have been wondering why certain things that used to feel easy now feel effortful, this conversation gives you a biological explanation and a practical path forward.You can find Tj at: Website | Instagram | Episode TranscriptNext week, we are sitting down with Dr. Vonda Wright to talk about why most of what you have been told about aging is actually data about people who did nothing. The decline curve, it turns out, is negotiable, and ages 35 to 45 are the highest-leverage window. But she also makes the case that the door never closes. Be sure to follow Good Life Project wherever you get your podcasts so you don't miss it.Check out our offerings & partners: Join My New Writing Project: Awake at the WheelVisit Our Sponsor Page For Great Resources & Discount Codes Hosted on Acast. See acast.com/privacy for more information.

Discover why hormones are off and what's really driving the imbalance. In this episode, we break down five root causes — from gut dysfunction and disrupted sleep to chronic stress, appetite dysregulation, and omega-3 deficiency — and walk through what you can actually do to fix it. FEATURED PRODUCT Berberine is a powerful botanical compound that acts as a natural GLP-1 supporter — the same metabolic pathway targeted by medications like Ozempic — helping regulate blood sugar, reduce insulin resistance, and restore appetite signaling from the gut. Since metabolic hormones like insulin and leptin are the first to derail your entire hormone cascade, Berberine directly addresses one of the deepest root causes discussed in this episode. It also supports gut microbiome diversity, making it a foundational tool for anyone working to reclaim hormonal balance naturally.

Today I'm sharing some of the “weird” things I do that actually support my ADHD brain.Because sometimes the things that look a little random from the outside are actually clever little accommodations in disguise.I'm talking about:Why I delay-send emails instead of trusting my brain has remembered everythingWearing activewear under my “real people clothes”Changing up my work environment for novelty, comfort & focusLetting myself task-switch without turning it into a moral failingDoing brain dumps when my mind feels like 47 browser tabs are openThis episode is a permission slip to stop judging the things that help you function & start seeing them for what they really are:ADHD-friendly support strategies.Weird? Maybe.Helpful? Absolutely.In this episode I mention the ETSY store I created with my friend Logan: NDHQ - come check it out.LINKS TO GOOD SH*T:*Join Adulting with ADHD your ADHD toolbox & everything you need to work with your brain*Get our ADHD Coach in your pocket! + the ADHD Goal Setting Workbook (life planner tool)*12 Things I wished my Doctor had told me about Adult ADHD*Find out if you might be living with ADHD - Download Symptoms List*Check out Courses & Coaching with Xena*Learn, Inspire, Share & Connect inside our Facebook Community *Come hang out with me on Instagram!

Self-care podcast exploring Fears of Weight-Gain After Losing Weight, Weight-Loss and Chasing Dopamine & Ways to Create Sustainable Weight-Loss Easy to Maintain. TOPICS:: ** Fears of Weight-Gain After Losing Weight (07:25). ** Weight-Loss and Chasing Dopamine (28:48). ** Ways to Create Sustainable Weight-Loss Easy to Maintain (40:25).   NOTES:: Show notes: amberapproved.ca/podcast/671 Leave me a review at amberapproved.ca/review Email me at info@amberapproved.ca   Take the NEW Free Hormone Imbalance Quiz here: https://amberapproved.ca/hormone-imbalance-quiz    Subscribe to newsletter: https://amber-romaniuk.mykajabi.com/newsletter-sign-up    SHOW LINKS: Click below to schedule a 30 minute Complimentary Body Freedom Consultation https://amberapproved.ca/body-freedom-consultation/  Take my free Emotional Eating Quiz here: http://amberapproved.ca/emotional-eating-quiz Listen to Episode 668 about what it's like to work with me here: https://amberapproved.ca/podcast/668  Follow me on Instagram www.instagram.com/amberromaniuk Youtube Channel: https://www.youtube.com/@amberromaniuk/    MY PARTNERS: Designs For Health Blood Sugar Bundle! One of the hardest parts of overcoming my emotional eating was the INSANE SUGAR and carb cravings. It was the intense sugar and carb cravings. That's why I created my Blood Sugar Bundle with Designs for Health to support your body while you work on emotional eating and breaking binge patterns. It includes chromium for blood sugar balance, L-glutamine to help curb cravings fast, a high-quality probiotic for gut health, and a clean Pure Paleo protein powder to keep you full and stable. I only recommend Designs for Health to my clients because they are third-party tested, family-owned, and use the highest quality ingredients. Quality matters when it comes to truly supporting your body and getting results. Get 30% off The Blood Sugar Bundle in USA and Canada automatically applied at checkout below! Canada Blood Sugar Bundle here for 30% off!  USA Blood Sugar Bundle here for 30% off! You can also get 30% off any Designs for Health supplements anytime, it's my gift to you. Canada: www.designsforhealth.ca  (code AMBER30) USA: www.designsforhealth.com (code AMBER88)

Episode 399 reviews Phase 2 of Season 15 and introduces the Motivation Loop — the sequence of meaning, belief, attention, action, reward, and recovery that drives sustained effort. The episode explains common loop breakers (loss of meaning, negative thoughts, distracted attention, too much challenge, poor recovery, and no visible progress) and how to diagnose which link is failing. Practical takeaway: identify your gap, reconnect purpose, protect attention, celebrate small wins, and balance challenge with recovery to keep motivation alive. In This Episode 399, We Will Cover: ✅ The Motivation Loop — what it is, why it matters, and how it influences behavior, focus, effort, and achievement. ✅ What Keeps the Loop Alive — the role of meaning, belief, attention, action, reward, recovery, and growth. ✅ What Breaks the Loop — how loss of meaning, negative thoughts, distraction, lack of progress, poor recovery, and burnout weaken motivation. ✅ The Neuroscience of Motivation — why the brain repeats what it rewards and how dopamine reinforces behavior. ✅ The Difference Between Challenge and Burnout — finding the sweet spot where effort creates growth instead of exhaustion. ✅ My Personal Motivation Loop Story — how I watched my own loop begin to break in real time while pushing too hard with hiking and what I learned from it. ✅ How to Repair a Broken Loop — practical strategies to restore motivation before burnout takes hold. ✅ The Anterior Mid-Cingulate Cortex (AMCC) — the brain region associated with persistence, self-regulation, resilience, and doing hard things. ✅ Why Doing Hard Things Grows the Brain — how meaningful challenges strengthen the neural circuits responsible for sustained effort. ✅ Finding Your Gap — using our Brain's Operating System framework to identify where your system may be out of alignment. ✅ The Biggest Lessons from Phase 2: Neurochemistry & Motivation — insights from Bob Proctor, Dr. Caroline Leaf, Dr. John Medina, Dr. Anna Lembke, Dr. Chuck Hillman, and Friederike Fabritius. ✅ What's Next — a preview of Episodes 400 and 401 on Leadership and Trust, and our transition into Phase 3: Movement, Learning & Cognition. Key Question of the Episode "When motivation begins to disappear, have we lost our drive—or is there simply a broken link in the loop?" Aha Moment The goal isn't to push harder. The goal is to identify the broken link, repair it, and keep the loop alive. EP 399: The Motivation Loop: What Keeps It Going—and What Breaks It? Welcome back to the Neuroscience Meets Social and Emotional Learning Podcast. This week, we're wrapping up Phase 2: Neurochemistry and Motivation. Over the past several months, we've explored some of the most important drivers of human behavior, attention, effort, learning, and performance. Through the work of Bob Proctor, Dr. Caroline Leaf, John Medina, Dr. Anna Lembke, Chuck Hillman, and Friederike Fabritius, we've been focused on one fundamental question: What drives sustained effort and forward movement? Today, I want to zoom out and connect everything we've learned into one simple framework: The Motivation Loop. More importantly, we'll look at: What keeps the loop going What causes it to break How we can strengthen it over time And why doing hard things may actually help grow parts of our brain responsible for persistence and self-regulation. The Brain's Operating System of Human Performance Before we dive into the Motivation Loop, let's remember what we've covered so far. One of the biggest insights from neuroscience is that high performance doesn't happen in one part of the brain. It happens through a sequence. Just like a computer has an operating system, our brains have an operating system for learning, achievement, and human performance. Over the past several months, we've been building that system one phase at a time. Phase 1: Regulation & Safety REGULATE The first question we asked was: "Is the nervous system safe enough to learn?" Before motivation... Before focus... Before performance... The brain must first feel regulated. Through guests like Bruce Perry, Kristen Holmes, Antonio Zadra, and Sui Wong, we learned that: Sleep matters Recovery matters Rhythm matters Our Stress levels matter A dysregulated brain struggles to learn. No regulation. No learning. Phase 2: Neurochemistry & Motivation ENGAGE Once the brain is regulated, we move to the next question: "What drives behavior, focus, and sustained effort?" This is the phase we've just completed. We explored: Dopamine Belief Thought patterns Attention Reward Burnout Energy And perhaps the biggest lesson from this phase was: The brain repeats what it rewards. This became the foundation of what I've called: The Motivation Loop: What Keeps the Loop Going? Looking at this graphic, notice the green side first. The healthy loop begins with: Meaning and Purpose When we know why something matters, effort becomes easier to sustain. This was Bob Proctor's message and the message that launched author Simon Sinek's entire career (Knowing Your Why). People can tolerate enormous challenges when the goal is meaningful. Example: Learning a New Skill Imagine someone deciding to learn a new language. At first: Progress is slow. Mistakes are frequent. The work feels uncomfortable. But they have a purpose. Maybe they want to connect on a deeper level with family. Maybe they want to travel. Maybe they want a new career opportunity. Purpose keeps them engaged long enough to continue with the hard work.   Belief Shapes Thought If I believe I can improve, my thoughts become more constructive. This was Dr. Caroline Leaf's work. Our thoughts influence our neurochemistry. Positive thoughts don't guarantee success. But they keep us moving toward it. Attention Drives Growth This was John Medina's contribution. Attention determines what the brain decides matters. The brain learns what we repeatedly focus on. What we attend to, we strengthen. Action Creates Progress Once attention is focused, behavior follows. We study. We practice. We train. We learn. Reward Reinforces Behavior This was Dr. Anna Lembke's work. The reward doesn't have to be huge. Sometimes it's simply noticing progress. The brain says: "That effort produced a result." And the loop continues. Example: Exercise A person begins walking 20 minutes every day. Week 1: No major changes. Week 2: Energy improves. Week 3: Sleep improves. Week 4: Resting heart rate begins dropping. The brain notices progress. The effort feels worthwhile. The loop strengthens. The behavior repeats. We have spent a lot of time on understanding how to keep the loop from breaking. How the Loop Breaks Now let's look at the red side. How the loop breaks. The loop rarely breaks all at once. Usually one link weakens first. Then the others follow. Loop Breaker #1: Loss of Meaning What Happened? A student studies only to pass a test. The test ends. The reason disappears. Motivation disappears. The loop breaks because there is no longer a compelling "why." What Could Have Prevented It? Reconnect to purpose. Instead of: "I have to study for this test." Shift to: "I'm building skills for the future version of myself." Bob Proctor taught us that goals are not just about achievement. They're about growth. Loop Repair Ask: "Why does this matter beyond today?" When meaning returns, motivation returns.   Loop Breaker #2: Negative Thought Patterns What Happened? Someone starts a health journey. After a difficult week they think: "I'm failing." "Nothing is changing." "I'll never get there." Their attention shifts toward evidence of failure. The loop weakens. What Could Have Prevented It? Focus on progress instead of perfection. Dr. Caroline Leaf would remind us that thoughts influence neurochemistry. A better question might be: "What is improving that I haven't noticed yet?" Loop Repair Look for small wins. Better sleep More energy More consistency Better habits Progress fuels dopamine. Dopamine fuels effort.   Loop Breaker #3: Distracted Attention What Happened? You sit down to work. A text arrives. Then email. Then social media. Then another interruption at your office door. Attention becomes fragmented. Learning slows. Progress slows. Reward disappears. What Could Have Prevented It? Protect your attention. John Medina taught us: Attention determines what the brain decides matters. Loop Repair Create: 30-minute focus blocks Phone-free work periods (with notifications turned off) One-task-at-a-time sessions The brain rewards completion. Not multitasking.   Loop Breaker #4: Too Much Challenge What Happened? This one surprises many people. Doing hard things strengthens the brain. But doing impossible things breaks the loop. A person starts: A new diet A new exercise plan A new business A new habit And tries to change everything at once. The challenge becomes overwhelming. What Could Have Prevented It? Start smaller. The AMCC grows when challenges are difficult but achievable. Loop Repair Ask: "What's the smallest difficult thing I can consistently repeat?" Not: "What's the hardest thing I can do today?"   Loop Breaker #5: Poor Recovery/Low Energy   What Happened? This is actually my hiking example that I've mentioned previously. Everything was working. My recovery improved. My WHOOP age improved 6.4 years younger than my actual age. My fitness improved- v02 max increased. Then I increased the challenge. Longer hikes. More strain. More effort. But not enough recovery time in between. I could actually see the reward disappearing in real time. The effort at the end of these longer hikes felt exhausting instead of energizing. I know that doing difficult things makes my brain stronger, but I was close to giving up on something I really enjoyed. What Could Have Prevented It? Recovery needed to increase alongside challenge. The mistake wasn't hiking, or making the hike more challenging. The mistake was believing: More is always better. Loop Repair Alternate: Hard days Easy days Increase recovery as strain increases. As Friederike Fabritius taught us: Performance isn't built through effort alone. It's built through effort and recovery. Once I put more attention on recovery before pushing again, the broken motivation loop repaired, and the end of those difficult hikes became energizing again (with the right amount of rest).   Loop Breaker #6: No Visible Progress What Happened? A salesperson makes: 50 calls 100 calls 150 calls No results. The brain begins asking: "Why bother?" The reward disappears. What Could Have Prevented It? Measure leading indicators instead of outcomes. Instead of focusing only on sales: Track: Calls completed Meetings booked Relationships built Skills improved Loop Repair Celebrate effort metrics. Not just outcome metrics. The brain needs evidence that effort matters. Also, if the strategy you are using is not yielding results, try a different one. Ask others who are having success, what they are doing, and how they are getting results. Once you can identify where your loop is breaking, fixing it requires doing something that you were not doing before.   The Big Lesson Every loop break in this phase points back to one question: What link failed? Was it: Meaning? Thoughts? Attention? Progress? Recovery? Challenge? Because the loop rarely breaks all at once. Usually one link weakens first. And the good news is: If you can identify the broken link, you can repair the loop. What About Doing Hard Things? One of the most fascinating concepts we explored this phase was the work surrounding the: Anterior Mid-Cingulate Cortex (AMCC) This area of the brain appears to play an important role in: Persistence Self-regulation Attention control Doing things we don't feel like doing Research suggests this area strengthens when we repeatedly choose meaningful challenges. Not impossible challenges. Not burnout. Not exhaustion. Meaningful challenges. Example Choosing: The workout you don't feel like doing. The difficult conversation you've been avoiding. The presentation that makes you nervous. The study session when you'd rather scroll your phone. Every time we choose effort over comfort, we may be strengthening the neural systems responsible for persistence and researchers also would say, the will to live. The Secret to Keeping the Loop Going After everything we've learned this phase, the answer is surprisingly simple: The loop stays alive when effort feels worthwhile. That means: ✅ Meaning ✅ Purpose ✅ Focus ✅ Progress ✅ Recovery ✅ Challenge But not too much challenge. Because challenge without recovery becomes burnout. And recovery without challenge becomes stagnation. The sweet spot lies in the middle. Instead of blaming ourselves, we can start diagnosing the system to build a stronger, more resilient version of ourselves. How to Use the "Find Your Gap" Framework Whenever you feel: Stuck Unmotivated Burned out Distracted Overwhelmed Plateaued Ask yourself: Which phase is broken? Because the problem is rarely "everything." Usually it's one phase creating a bottleneck for the others.   Phase 1 Gap: Regulation & Safety Ask: Am I sleeping well? Am I recovered? Is stress overwhelming me? Is my nervous system regulated? Signs This Is Your Gap Anxiety Exhaustion Brain fog Poor sleep Irritability Example A teacher can't focus. They assume they need more motivation. But they're sleeping 5 hours a night. The real gap isn't motivation. It's regulation. Solution Fix: Sleep Recovery Stress management First.   Phase 2 Gap: Neurochemistry & Motivation Ask: Do I still know why this matters? Am I seeing progress? Has the reward disappeared? Have I lost momentum? Signs This Is Your Gap Procrastination Lack of drive Loss of enthusiasm Feeling stuck Example This was your hiking example. You still had the ability. You still had the discipline. You simply stopped feeling rewarded by the effort. Solution Repair the Motivation Loop: Reconnect to purpose Reduce challenge temporarily Improve recovery Look for progress   Phase 3 Gap: Movement, Learning & Cognition Ask: Am I moving enough? Am I physically engaged? Am I learning new things? Is my brain being challenged? Signs This Is Your Gap Low energy Mental sluggishness Poor concentration Feeling mentally flat Example Someone spends 10 hours at a desk. Their motivation is fine. Their sleep is fine. But they're sedentary. Movement is the missing ingredient. Solution Move first. The research from Chuck Hillman and John Ratey suggests movement often improves: Attention Mood Learning Memory   Phase 4 Gap: Perception, Emotion & Social Intelligence Ask: Am I seeing this situation clearly? Am I understanding others? Do I feel connected? Signs This Is Your Gap Conflict Miscommunication Isolation Emotional reactivity Example A leader thinks: "Nobody supports my vision." But the real issue is communication. The gap isn't motivation. It's perception. Solution Improve: Listening Emotional awareness Perspective-taking Relationships   Phase 5 Gap: Integration, Insight & Meaning Ask: Does this align with who I want to become? Am I moving toward something meaningful? Do I have clarity? Signs This Is Your Gap Success without fulfillment Feeling lost Lack of direction Constantly chasing goals Example Someone has achieved everything they wanted professionally. But they still feel empty. The gap isn't performance. It's meaning. Solution Reconnect with: Values Purpose Identity Contribution to the World. The Most Powerful Question At the end of every week, ask: "Where is my gap?" Is it:

Why is it that some of the most intelligent, successful, self-aware women can find themselves completely distracted by a man?Why do we suddenly start checking our phones more often, replaying conversations in our heads, neglecting our routines, and feeling emotionally impacted by someone we've only known for a matter of weeks?In this episode of The Upgrade Edit, I'm diving into the fascinating neuroscience behind attraction, attachment, and self-abandonment.After spending almost three years celibate, I experienced some of the biggest growth of my life. My business expanded, my confidence deepened, my connection to myself strengthened, and I built a life that felt rich, purposeful, and aligned.Now that I'm dating again, I've found myself reflecting on a powerful question:Why do so many women lose themselves in love?Together, we'll explore the role dopamine plays in attraction, why your brain can mistake chemistry for compatibility, how attachment patterns influence dating behaviours, and why your nervous system is often seeking familiarity rather than what's actually best for you.This isn't an episode about becoming independent or avoiding relationships.It's about learning how to stay connected to yourself whilst allowing love into your life.Because the goal isn't to stop loving others.The goal is to stop abandoning yourself in the process.In this episode, we explore:• Why early-stage attraction can feel addictive• The role dopamine plays in dating and relationships• Why your brain is wired to seek connection• How attachment styles shape romantic patterns• The difference between chemistry and compatibility• Why healthy love can initially feel unfamiliar• How women are conditioned to prioritise others over themselves• The subtle signs of self-abandonment in dating• What three years of celibacy taught me about self-worth, purpose, and fulfilment• How to remain grounded, embodied, and connected to yourself whilst datingReflection Questions• What happens to my energy when I start dating someone?• What parts of myself tend to shrink when romantic feelings grow?• Am I seeking connection, or am I seeking validation?• What practices help me stay anchored in myself?• Am I building a life that feels exciting outside of a relationship?Connect With DavinaFollow along on Instagram: @davvyxxExplore retreats, coaching, embodiment work, and upcoming events via the links in my bio.If this episode resonated with you, please share it with a friend or post it to your stories and tag me. Every share helps this message reach more women who are ready to stop chasing love and start coming home to themselves.Because the healthiest relationships aren't built by two people looking to be completed.They're built by two whole people who choose to walk alongside one another. ❤️‍

Do you have restless legs at night? Discover the underlying cause of restless leg syndrome, how to stop getting leg cramps at night, and how to fix the sleep problems caused by restless legs within 72 hours.0:00 Restless legs at night0:54 What causes restless legs syndrome? 1:14 Dopamine and restless legs syndrome1:56 Iron and nerve health 2:30 Why you have restless legs at night 3:13 Mineral deficiencies and restless legs syndrome5:25 More restless legs syndrome causes6:34 What causes the mineral deficiencies related to restless legs syndrome?7:20 Restless legs relief

Stupid News 6-12-2026 6am ...Got any of that Dopamine? ...Replaced by goats ...Not 1 or 2 but 3!!

This week on Overpowering Emotions, Dr. Caroline breaks down the vagus nerve, the gut-brain connection, and why emotional regulation starts in the body long before it reaches conscious thought. From “hangry” and “hanxious” kids to the role of sleep, hydration, protein, and stress beliefs, this episode explains why emotional overwhelm is often physical before it becomes behavioral.Dr. Caroline shares eye-opening research on anxiety, stress, dopamine, serotonin, and the stories children tell themselves about their emotions. You'll hear why a racing heart before a test is not a sign something is wrong, how processed foods can fuel dysregulation, and why the words adults use around anxiety can shape a child's nervous system response.This episode offers practical ways to support emotional regulation through nutrition, body awareness, and everyday conversations that help kids feel safe in their own bodies.Topics covered include:- The vagus nerve and body-to-brain communication- Why emotional regulation starts with sleep, food, hydration, and movement- The gut-brain connection in children and teens- Dopamine, serotonin, and how food affects mood- Why kids need adults to validate physical symptoms of anxiety- How language changes emotional responses- Research on stress beliefs, anxiety, and resilience- Helping children reinterpret physiological sensations with confidenceThis episode is packed with science-backed ideas that are easy to apply in any context.Homework Activities for Adults Supporting Children & TeensBody Basics Check-InTrack for one week:- Sleep- Hydration- Breakfast habits- Protein intake- Mood patterns after meals or missed mealsResource Needed:Simple daily tracker or notes appPre-Stress Fuel RoutineBefore school, sports, tests, therapy, or social events:- Add protein + complex carbs- Encourage water intake- Avoid sugary breakfasts when possibleSuggested Foods Mentioned:- Eggs- Nuts/nut butter- Fish- Walnuts- Chia seeds- YogurtNormalize Physical Anxiety ResponsesPractice phrases like:“Your body is trying to protect you.”“That racing heart means your body is getting ready.”“This feeling makes sense.”Avoid:“It's all in your head.”“Calm down.”“There's nothing to worry about.”Teach Kids to Notice Body SignalsUse a body map activity:- Where do they feel stress?- Tight chest?- Upset stomach?- Warm face?- Fast heartbeat?Help them connect physical sensations to emotions without judgment.Resource Needed: Printable body outline or journalReframe Stress ConversationsReplace:“Stress is bad.” with:“Your body is preparing you for something important.”Encourage kids to see stress signals as information, not danger.You can listen to the episode about the body map and emotional health here: https://youtu.be/nZ7FScCe1lsEnjoying the show? Help out by rating this podcast on Apple to help others get access to this information too! apple.co/3ysFijh Follow Dr. Caroline YouTube: https://www.youtube.com/@dr.carolinebuzankoIG: https://www.instagram.com/dr.carolinebuzanko/ LinkedIn: https://ca.linkedin.com/in/dr-caroline-buzankoFacebook: https://www.facebook.com/DrCarolineBuzanko/Website: https://drcarolinebuzanko.com/Resources: https://drcarolinebuzanko.com/resources/articles-child-resilience-well-being-psychology/ Business inquiries: https://korupsychology.ca/contact-us/Want to learn more about helping kids strengthen their emotion regulation skills and problem-solving brains while boosting their confidence, independence, and resilience? Check out my many training opportunities! https://drcarolinebuzanko.com/upcoming-events/

I just wrapped the first in-person AI & Sheep workshop at my farm, and I couldn't let these takeaways leave my brain before I got them on record. The truth is, most people are losing ground to AI, not gaining it — they're in the dopamine pool, working longer, building more, and not seeing a single dollar of return. So before anyone goes another week adding tools and workflows to their life, I want to share the core philosophy I teach: if AI isn't making you more money or buying back your time, it's a distraction. This episode walks through Problem First Building — starting with a specific, rantable problem instead of a vague goal — and the 1-2-3 Framework I use to deconstruct every workflow step by step.

What if some of the struggles spiritual entrepreneurs experience with money are not simply about discipline, willpower, or mindset but are also connected to the brain and nervous system? In this thoughtful and compassionate episode of the Money Lighthouse Podcast for Spiritual Entrepreneurs, Michel explores the fascinating connection between dopamine and money — and how understanding the brain's reward system can help create a healthier, calmer, and more supportive relationship with finances.In this episode, listeners will learn a simple explanation of dopamine and how it influences motivation, anticipation, avoidance, emotional spending, entrepreneurship, and even the way many people react to checking bank accounts or managing financial tasks. Michel also explores how online business environments and modern digital life can unintentionally create cycles of dopamine chasing, emotional highs and lows, comparison, urgency, and nervous system exhaustion — especially for sensitive, intuitive, and creative spiritual entrepreneurs.Most importantly, this episode offers gentle, practical ways to begin healing and reshaping one's relationship with money through safety, awareness, consistency, and compassionate self-understanding. From celebrating tiny money wins and creating calming money rituals to reducing shame around avoidance and building sustainable financial habits, this conversation is both grounding and deeply encouraging for anyone who desires a more peaceful and empowered relationship with abundance.Topics CoveredWhat dopamine is and how it worksThe connection between dopamine and moneyWhy entrepreneurship can feel emotionally intenseDopamine, anticipation, and reward cyclesEmotional spending and money avoidanceThe nervous system's role in financial behaviorsWhy checking money can feel stressfulHealthy dopamine and gentle motivationCreating safer and calmer money habitsSmall financial wins and positive reinforcementSocial media, online business, and dopamine chasingBuilding a healthier relationship with money through awareness and compassionIf you've ever felt overwhelmed, emotional, avoidant, reactive, or anxious around money, this episode is a gentle reminder that you are not broken — and that understanding your brain and nervous system can become a beautiful part of your money healing journey. Tune in for an uplifting and insightful conversation that blends neuroscience, spirituality, emotional awareness, and practical support for spiritual entrepreneurs.Contact:michel@moneylighthouse.com

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Dr. Deb Muth 00:00:09 Hi there, how are you? Bob Miller 00:00:10 Excellent! Pedaling as fast as humanly possible, but doing okay. Dr. Deb Muth 00:00:14 Good, good. Well, I’m looking forward to our conversation today. This should be amazing. Bob Miller 00:00:20 Yeah, it should be a lot of fun. Dr. Deb Muth 00:00:22 Yeah, anything that’s off-limits for you in, our conversation? Bob Miller 00:00:28 No. Dr. Deb Muth 00:00:29 Okay, anything you want me to make sure we cover for you? Bob Miller 00:00:33 Well, I mean, is it okay if we put a little plug-in for our software? Dr. Deb Muth 00:00:35 Absolutely. Bob Miller 00:00:36 Yeah. Dr. Deb Muth 00:00:37 Absolutely. Bob Miller 00:00:36 Yeah. Dr. Deb Muth 00:00:37 Absolutely. Bob Miller 00:00:38 Hey, can we… can we do a screen share? Yes, we can. Yeah, because I want to show you some maps, and… Dr. Deb Muth 00:00:43 Okay. Things like that, yeah, so… Perfect. So just let me know when you want to do screen share. Bob Miller 00:00:48 Okay. Dr. Deb Muth 00:00:49 And yeah, feel free to plug your software wherever you want to. Bob Miller 00:00:53 Okay, well, good. Let me pull up a, a slide for that, and give me one second, I just want to shut the door to my office to get the noise down. Dr. Deb Muth 00:01:01 No worries. Bob Miller 00:01:16 And, how should I refer to you? Dr. Debb? Dr. Muth, what do you like? Dr. Deb Muth 00:01:18 Dr. Deb is great, or Deb, either way, I’m pretty informal, so… Bob Miller 00:01:22 Yeah, and… Bob is fine for me. Okay. Yeah. Yeah, there you go. Why people feel like they need this, son. Special name, it’s like, seriously. Dr. Deb Muth 00:01:33 Right? I agree. Bob Miller 00:01:35 When I work with my clients, it’s like, Dr. Millison, just, just bop, just, just bop. Dr. Deb Muth 00:01:41 Yep, that’s how I am, too. Just call me Deb, it’s good. Dr. Deb Muth 00:01:44 They feel a little awkward with that, you know? They’re not used to that, but… Bob Miller 00:01:48 Alright. And you’re a naturopath, medical doctor. Dr. Deb Muth 00:01:52 A nastropathic doctor and a nurse practitioner. Oh, nice. Yeah, so I got the best of both worlds, right? Bob Miller 00:01:58 Yeah, damn. Okay. Alright, so here we go… There we go. Alright, so I got that ready, and then I will do a, I will do a screen share. I think you’re gonna really, appreciate what we’ve come up with. We’ve come up with the concept of, Cellular CPR. Dr. Deb Muth 00:02:23 Oh, nice! Bob Miller 00:02:24 And that is, construct the cell membrane, Protect the cell membrane. And restore it if it’s damaged. Dr. Deb Muth 00:02:32 Love that. Bob Miller 00:02:34 I love that. Yeah, so that’s what we’re focusing on, and then how, You know, we want to get to the point that, you know, most people think of genetics, they think of, like, 23andMe or Ancestry. Dr. Deb Muth 00:02:44 Yeah. Bob Miller 00:02:45 And then you have the professional geneticists who are looking at, you know, odd things that could create a disease. We’re looking at functional genomics. Dr. Deb Muth 00:02:54 Which is so much better. Bob Miller 00:02:56 Yeah. Are you familiar with what we do here, or… Dr. Deb Muth 00:02:58 A little bit, a little bit. So, it’ll be new to me, too, so I’m excited. Bob Miller 00:03:03 And how much time do we have? Dr. Deb Muth 00:03:04 We have an hour, give or take a little bit on either side. Do you have a hard stop anywhere? Bob Miller 00:03:10 No, no, I put a, I moved my clients around, and I don’t have anybody till, 3.30, so we’re good. Okay. Dr. Deb Muth 00:03:16 Perfect. Alright. Bob Miller 00:03:18 It’s like we’re getting started early as well, so… Dr. Deb Muth 00:03:19 Yeah, we’re getting started a little bit early, so that’s good. Bob Miller 00:03:22 Yeah, I just got my office cleaned up, so… Dr. Deb Muth 00:03:23 Okay, good. All right, are you all set to get started? Bob Miller 00:03:28 I’m good to go, my friend. Dr. Deb Muth 00:03:29 I’m gonna just record a little intro and a little bit of a, hook for people, and then we’ll get started. I’ll ask you to kind of tell us a little bit about yourself, and then we’ll just take this conversation wherever it’s supposed to go. Bob Miller 00:03:39 Okay, you got it. Dr. Deb Muth 00:03:40 Alright, sounds good. So what if the reason you’re not healing isn’t your diet, your supplements, or your labs, but it’s actually your genes? Dr. Bob Miller is uncovering how genetic variants, when combined with modern toxins, explain why some of us stay sick no matter what we try. Today, we’re talking genetic pathways, detox blocks, and the new science every wellness warrior needs to know. Welcome back to Let’s Talk Wellness Now, the show where we uncover the root causes of chronic illness, exploring cutting-edge regenerative medicine, and empower you to heal from the inside out. I’m Dr. Deb, your medical detective, and today, our guest, Dr. Bob Miller, is a true pioneer in functional genomics. He’s a board-certified traditional naturopath and the founder of Neutrogenetic Research Institute. And he’s the leading groundbreaking research on how genetic variants influence chronic illness, inflammation, and detoxification. His work has been recognized on international stages, uncovering links between genetic expression and conditions like Lyme disease, mast cell activation, or MCAS, and mitochondrial dysfunction. I’m so excited to talk to Dr. Bob today. He is gonna reveal some things that even I don’t know about, so I’m excited to learn alongside of you guys. So… Dr. Bob, let’s get started. Tell us a little bit about yourself, and kind of how you got on this journey. Bob Miller 00:05:04 Well, that’s, that’s interesting. I was sort of like a mid-career coming to the natural health field, because in my early 30s, I found myself with a severe case of ulcerative colitis. Bob Miller 00:05:15 And I was in the hospital for 21 days. probably within hours of death, pleading to death. And they told me I’ve got one option, and that is cut out the colon and wear a bag. Didn’t sound like a lot of fun. Dr. Deb Muth 00:05:27 Not an option I would want. Bob Miller 00:05:29 So, you know, the medical folks wasn’t real happy with me, but I said, yeah, I’d like to explore some alternative things.Never thinking that I’d get into this field, and then I just, you know, worked with some herbalists and things that I found absolutely fascinating. So, that’s how I got into this around 30 years ago. And, haven’t looked back since, and just having a… having a blast as we now move into how our genetics impacts things. So, that’s what we’re gonna… that’s what we’re gonna talk about today. Dr. Deb Muth 00:05:58 I’m excited to talk about this genetic thing. When you started over 30 years ago, what kind of patience and problems first inspired you to dig deeper into that root cause healing and kind of get into the genetic piece of it? Bob Miller 00:06:10 Sure. Well, you know, as a… now, I’m in a part of the country called Lancaster County, Pennsylvania, where there’s a lot of Amish and Mennonite, and they gravitate towards these things.So, this is their first thing to do, and that doesn’t work, then they’ll go other routes. So, you know, back then, we just saw typical, you know, a little tired, constipation. You know, a little bit of fatigue, arthritis, those kind of things. But things have changed dramatically over the years, as people are now getting more chronically sick. You know, it’s worse than it’s ever been. And what we’re finding is the, the culprits Primarily is mold exposure and Lyme disease. When people get those two together, they’re just… it’s an inflammatory cascade that nobody can seem to unravel. So that’s where we spend a lot of our time. And we’re also spending a lot of time looking at mental health, like ADD, ADHD. And, we give… this year I’ll be speaking at three autism conferences. And we can dig into that a little bit as to why we think we’re seeing such a dramatic increase. And aside from autism, that used to be 1 out of 1,000, now it’s 1 out of 33, or 23. You know, we’re also seeing dramatic increases in ADD, ADHD. People are stressed out. And today, I think we’ll have the time to actually go through and show how environmental factors combine with genetics to cause that to happen. So we’ll… we should have a fun visit here today. And today, I think we’ll have the time to actually go through and show how environmental factors combine with genetics to cause that to happen. So we’ll… we should have a fun visit here today. Dr. Deb Muth 00:07:37 This should be a fun visit. We can cover lots of topics. I am so excited. So, you founded Nutri Genetic Research Institute in 2015. What did you hope to accomplish, and what kind of surprised you in your findings so far about that? Bob Miller 00:07:51 Well, you know, let’s back up at what, you know, genetics is used for. Everybody’s familiar with 23andMe and Ancestry that, you know, tells you where your ancestors came from. Then you have your professional geneticists. I mean, these are people with a degree in genetics. And they’ll look for, you know, very odd sort of things that are prone to relate to a disease. So there are disease-related genetics. Well, in functional, we don’t look at either of those. We look at For example, how you’re breaking down your fats and utilizing them. How you’re recycling your glutathione. How you might be handling your iron. And none of those are disease-causing on their own.And none of those are disease-causing on their own. But when they pile up on you, and then combine that with environmental factors, that’s when things start to go south on us. So, that’s what we’re doing, we’re looking at patterns. And our first foray into this was, we did studies on Lyme disease. And our first foray into this was, we did studies on Lyme disease. So, we looked at, like, I think 50 people with Lyme disease. We looked at their genome. So, we looked at, like, I think 50 people with Lyme disease. We looked at their genome. And we found patterns that were more evident in those with Lyme. Now, this doesn’t… these genetics don’t mean you get Lyme, it just means if you get Lyme, you react worse to it. And we found patterns that were more evident in those with Lyme. Now, this doesn’t… these genetics don’t mean you get Lyme, it just means if you get Lyme, you react worse to it. So, as you know, some people get Lyme, they go on a round of antibiotics, and they’re done. So, as you know, some people get Lyme, they go on a round of antibiotics, and they’re done. Others have a little more struggle, and then others are struggling terribly for years. So there’s an old adage of genetics loads the gun, environment pulls the trigger. Dr. Deb Muth 00:09:14 Yeah, that is so true, and I think when we’re talking about Lyme and mold and things like that, we forget sometimes that our genetics can predispose us to be more sensitive to those things, and if we have genetic pathways where we don’t clear things properly, it’s harder for us to get them out of the body. And then you add on that whole rain barrel effect that we’ve always used as a functional medicine term, right? If the barrel’s half full, you’re okay. If it’s full, and now it’s spilling over, it’s a bigger problem. Have you guys found, too, that some of these environmental things actually are changing the genetics of people, or how they’re processing their own genetics? Bob Miller 00:09:53 Well, let’s go back to, Genetics 101. But we’ll go back a little bit further. So, what an interesting mechanism, what a miracle the body is. Bob Miller 00:10:03 Fats, carbohydrates, proteins, drink water, breathe air, expose the sunlight, and somehow everything gets made. I mean, when you just step back and think about that, it’s like, It’s pretty darn amazing. Dr. Deb Muth 00:10:15 I always tell women, you know, the fact that we get pregnant and we have healthy pregnancies and births is a miracle, because if we had to try to control that, that wouldn’t work so well. Bob Miller 00:10:25 Right. Well, that’s another miracle. These microscopic sperm and egg, human being, 9 months later, it’s like. But even inside of us. We are making our hair, our skin, our nails, our blood vessels, our ATP, our energy, it’s all being created. Well, that gets created by enzymes. So, enzymes take one substance, combine it with something else, and make something new. Then another enzyme comes along and does the same thing. Your DNA is the instructions on how to make the enzymes. So, when we are conceived. If it’s a, if it’s a female, of course, it’s the XX, the two chromosomes. You know, we’ve… everybody’s seen those… the genetics that… Listed pair. So, if it’s a female, the father donated the X enzyme. And the mother has no choice but to give the eggs, so that’s female. If the father donates the Y, you have a male that’s in chromosome number 1. Then 2 through 23 is the rest of the instructions on how to make enzymes. So, what can happen? We can get what are called SNPs, single nucleotide polymorphisms. And SNPs just mean that the instructions to make the enzyme’s not quite as good. So, if one parent gives a SNP on the making of an enzyme, The enzyme’s fine. It works. But, general rule of thumb, It may only work at 70-80% of efficiency. Now, a good analogy is think of an 8-cylinder and a 6-cylinder car. If parents give you good information, that’s like having an 8-cylinder car. If one parent gives you that snip, it’s like having a 6-cylinder car. Now, is a 6-cylinder car a fine car? Sure. It’ll get you from point A to point B, but it’s just going to have the power of an 8-cylinder. Then if both parents give you a SNP on the same enzyme, it may be 30-40%, and that’s like having a 4-cylinder car. Sits in the driveway, looks the same, puts gas in it, everything. But if you’ve got a 4-cylinder car. Probably not a good idea to go cross-country pulling a trailer behind you up and down mountains. Dr. Deb Muth 00:12:29 This is true. Bob Miller 00:12:32 So… We can get an 8-cylinder, 6-cylinder, or 4-cylinder enzyme. Now, if it’s not under a lot of stress, if that 4-cylinder car is just taking you to the bank and the grocery store. It’s just as good as an 8-cylinder car. But if you gotta pull that trailer, and there’s a lot of stress on it, being mountains, it’s gonna struggle. Now, there’s one other little caveat to this, and that is some genetic mutations are gain-of-function. They actually work faster. Now, we have enzymes that do all kinds of things. We have enzymes that make and recycle our antioxidants, but we also have enzymes that make inflammation. No, that’s a good thing, because if we get a virus or bacteria, if you didn’t make inflammation to kill it, well, we’d all die of infection. So, you know, we tend to think of free radicals as bad, antioxidants as good. They both play an important role. But interestingly, some of the major enzymes that make inflammation, they can be overactive. They can be turbocharged. And when they’re stimulated by environmental toxins, they overreact. Bob Miller 00:13:40 And therein lies the problem. When they overreact, we have a problem. Bob Miller 00:13:46 So, if we have genes that overreact when stimulated. And then the enzymes that take care of inflammation are underactive. Then you’re gonna be more inflamed. You know, the majority of people that, you know, come for functional medicine Or naturopathic help, or… Inflammation that they can’t seem to get under control. Dr. Deb Muth 00:14:06 Right. Bob Miller 00:14:07 And we will be, you know, during this hour, we’re going to look at some of the pathways that make that happen. So, what we can do then, we can’t change our genetics. When you’re conceived, that’s the hand you’re dealt. When your life would be over, if someone would take some tissue and measure, it’d be exactly the same as conception. Does it change. Bob Miller 00:14:28 The enzyme’s ability to do its job may be compromised. Because remember I said there’s a, the enzyme takes a cofactor. So an enzyme takes substance A, cofactor, make substance B. Well, if that cofactor’s not there, the enzyme’s not going to work either. So, you could have an 8-cylinder car, and if there’s no gas in it, it’s not going anywhere. So… It’s the strength of the enzyme, it’s the cofactor to do the A to B conversion. And that’s what we’re going to get into. So, many people say, well, where did these SNPs come from? Nobody knows for sure. Sometimes they’re what’s just called de novo, when the sperm and egg go together, the instructions get mixed up a little bit. We do believe a lot of it came from a long time ago, when we were almost wiped out by sexually transmitted diseases. And those STDs were altering the genes when the conception, in other words, when the sperm went into the egg, the STDs were interfering. And causing the problem, so… I often joke, if you want to blame somebody. Blame your great-great-great-great-great-great-great-grandparents for, being a bit promiscuous, so… Dr. Deb Muth 00:15:31 Yeah, for being… having a little too much fun, right? Bob Miller 00:15:35 So, we don’t know for sure, but, you know, there are some that, But most of the SNPs that we get inherit from our parents. So, if you look at a child. And you look at the SNPs. 99.9% of the time, it came from one of the parents. Dr. Deb Muth 00:15:50 In identical twins, do they have the exact same identical makeup? Bob Miller 00:15:54 Yep, Dr. Deb Muth 00:15:56 But not in fraternal twins, correct? Bob Miller 00:15:59 No, no, those could be different, Jeff. Dr. Deb Muth 00:16:00 It could be different because they have different sacs, they’re not sharing that same genetic makeup. Bob Miller 00:16:04 Yeah, so keep in mind, both your mother and your father have, you know, the two And so you get one from one parent, one from another. Dr. Deb Muth 00:16:13 So… Bob Miller 00:16:14 Interesting situation. I had, 3, 3 boys. And, we were looking at an enzyme related to breaking down oxalates. Now, the mother and father each had one SNP, and that’s called heterozygous. Three boys, and they all come together, they’re Amish boys, they’re a lot of fun. And I looked at their genomes, and the one boy didn’t have any SNPs at all. And one had won. And the other one had two. Dr. Deb Muth 00:16:41 Interesting. Bob Miller 00:16:42 So, we don’t quite know how these things get handed off, but with the parents each having one, you could have a child with none, one, or two. So, the one, his ability to break down oxalates, which is fine. The other one was slightly impaired, and the other one was dramatically impaired. So, you can have 3 children, and it all depends what the parents have. Now, if a parent has a homozygous, or 2 copies. And the other parent has nothing. Every child will have one. Okay. If both parents are homozygous, that they both have two, Every child will have two. Dr. Deb Muth 00:17:19 too. Bob Miller 00:17:20 Yes, so that’s the way it works, but, you know, but it’s somewhat rare that both parents are homozygous on an enzyme, but it can happen. Dr. Deb Muth 00:17:27 Do we think that infections today, like Lyme disease or mold exposure, things like that, if the parent, the woman, primarily, I’m thinking, is pregnant, and she actively has these infections. Can those infections affect the genetics, kind of like a past sexual transmission did where we thought back in the day? Bob Miller 00:17:47 Yeah, I… I mean, I’m not that much of a geneticist to answer that for sure, but my thought would be no, that at conception, the pattern’s made. Dr. Deb Muth 00:17:55 Okay. And then that’s… that’s the hand you’re dealt. Bob Miller 00:17:58 Yeah. So, I tell people we have good news and bad news. The good news is we can compensate for the weakness. The bad news is we can compensate for the weakness. Dr. Deb Muth 00:18:09 That is so very true. Bob Miller 00:18:11 Yeah, we can’t, because I often get asked, so we’ll do some things now, and we’ll check my genes again, and they’ll be better. It’s like, nope. Dr. Deb Muth 00:18:18 Oh, – – Bob Miller 00:18:19 You gotta play the hands you’re dealt, so… Dr. Deb Muth 00:18:21 That’s right. Bob Miller 00:18:22 You can test your genetics… if you’re looking at the same enzyme, you can test it every year. It’s not gonna change. It’s like the blueprint. Dr. Deb Muth 00:18:30 It’s good and bad, right? It’s the one test you only have to do once in your lifetime. Bob Miller 00:18:34 No, unless, you know, like, our. Dr. Deb Muth 00:18:36 All the time. Bob Miller 00:18:37 Yeah, now our test looks at, called the Functional Genomic Analysis Test of your genomic Resource. We look at 220,000 steps. Dr. Deb Muth 00:18:46 Wow, that’s a lot. Bob Miller 00:18:47 That’s not all of them. Dr. Deb Muth 00:18:49 Right. Bob Miller 00:18:50 So, maybe in the next year, we’re gonna come out with our third version of the chip. And then, if someone wants to get those new things that weren’t on it, they’d have to repeat. But whatever we measured is gonna stay the same. Dr. Deb Muth 00:19:03 That’s a lot of SNPs to look at. Bob Miller 00:19:05 Keeps us busy. Dr. Deb Muth 00:19:06 But there’s still, but there’s still SNPs that we. Bob Miller 00:19:09 That we’d like to have that we don’t have, so… Bob Miller 00:19:11 We started out with version 1 on our genetic test, then we worked with version 2, and we’re already compiling a list of what version 3 would look like. So if somebody has our version 2, And we’re saying, you know what, it’d be nice if we could see these, well, then you’d repeat, but it won’t change what you already know, so… Dr. Deb Muth 00:19:29 Got it, got it. So, when you started out, and you started looking at the research of Lyme disease and chronic infections, which detox pathways are most important for people who struggle with those conditions? Bob Miller 00:19:43 Okay. You know what might make sense as we do a screen share, and I’ll actually show you the pathway. Does that make sense? Bob Miller 00:19:48 Alright, so… let’s see if I… let me just press the share… Dr. Deb Muth 00:19:52 Yep, you should just be able to press share. Bob Miller 00:19:54 And… number 2. Okay. Are we seeing the screen there? Bob Miller 00:20:01 Okay. Dr. Deb Muth 00:20:02 So, this is a map that we made. Bob Miller 00:20:05 And by the way, this is not… All-inclusive of all the things we look at, but we believe this is a core issue. So, where we’re going to start here, there’s something called the microglia. And the microglia are glial cells. They’re in the brain and the central nervous system. And they’re very interesting little creatures, because most of the time, and this is just a drawing of what they sort of look like. Most of the time, they’re in what’s called the M2 anti-inflammatory mood. What that means, these little guys pick up dirt, debris, Recycle them. Turns on an enzyme called interleukin-10 that’s anti-inflammatory. And just kind of does general housekeeping. And just kind of does general housekeeping. However, when a trigger comes along. However, when a trigger comes along. They… it’s the same glial cell, but it moves over to a very pro-inflammatory enzyme. A pro-inflammatory glial cell. And it triggers these 3 enzymes, Actually, these four. That are pro-inflammatory. Tumor necrosis vector alpha, Interleukin-6. NF Kappa B, Inos. Now, these create inflammation. So you might think, well, why is that good? Well, if you have some foreign invader, virus, bacteria coming in, parasite. If you didn’t have these guys coming to the rescue, you would just die of infection. So, these guys are your friend unless they’re your worst enemy. Because TNFA, and we’ll show you when we actually do a demo account, TNFA can be overactive. So, in other words, it over-responds. Interleukin-6 can be overactive. And if Kappa-B can be overactive. The INOS, and I’ll explain each of these as we go through a demo, can be overactive. Now, what that means is, you’re very good at killing virus and bacteria. But this is where autoimmune disease comes in, and just inflammatory conditions. Now, this is just speculation, but we think what happened is, as you know. Thousands of years ago, we didn’t have refrigeration, we didn’t have sewer, we didn’t have pure water, and we didn’t have antibiotics. So, if you made it to 40, you were an old-timer, because everybody was dying of infection. So, what we believe happened is, by what’s called natural selection, Having these overactive. A thousand years ago was to your advantage. Dr. Deb Muth 00:22:31 Hmm. Bob Miller 00:22:32 But now… We have pure water, we have refrigeration, we have sewers, we have antibiotics. But now we have environmental factors that are stimulating them. Now it’s to our disadvantage. And we’ll talk about that a little bit as it relates to the hemochromatosis genes and maybe the G6PD. Dr. Deb Muth 00:22:48 Yep. Bob Miller 00:22:49 Now, why are we becoming so inflamed? Let’s look at the triggers. Now, one of my, favorite expressions is. I was born all the way back in 1954. Dr. Deb Muth 00:23:01 And it was a different world back then. Bob Miller 00:23:05 These are some of the triggers. And we’ll get into these, but right now, high fructose corn syrup, And the high-fat diet. High fructose corn syrup only came about in 1968. So now we’re being exposed to high fructose corn syrup. Then… we didn’t have these, these viruses like COVID. Dr. Deb Muth 00:23:26 Yeah. Bob Miller 00:23:27 Now, there’s now pretty strong evidence that COVID Was actually, you know, made as a gain of function. It’s debated, and I’m not taking an opinion on it, but there’s some people who believe Lyme disease was also a part of experimentation. Dr. Deb Muth 00:23:40 Go. Bob Miller 00:23:41 Then we have molds, and it appears as though mold is getting stronger. you know, 20 years ago, when I was seeing folks, mold wasn’t on the radar. I would say 7 out of the 10 folks we speak to today have mold problems. Yeah, 20 years ago, we talked more about mold allergy being an issue versus mold toxicity being an issue. Right. So… I know some folks are, you know, speculating what’s happening, but one of the theories out there is that EMF is strengthening mold. I don’t know if you ever heard that theory, and I don’t… Dr. Deb Muth 00:24:13 I have. Bob Miller 00:24:14 I’m not claiming it’s true, but it’s an interesting theory. Then even, you know, your black mold from water-damaged buildings. Then our air pollution is getting worse. We’re getting more toxic metals. Dr. Deb Muth 00:24:26 You know, if we have a… Bob Miller 00:24:27 You know, we’re gonna look back someday and say, what were we thinking, smearing aluminum into our armpits? The, what were we doing putting mercury in our teeth? Then, you know, glyphosate. When I was a kid, there was no glyphosate. So, all of these herbicides and pesticides. Polychlorinated biphenols, And then EMF. So, we love our cell phones, you know, and I think unless you, or in the middle of the desert, or down in a cave, you’re being exposed to EMF somewhere. So, you know, we have our cell phones with us, we have, We have Wi-Fi, the towers are everywhere. And we don’t know long-term, but we may find that this can… this creates some inflammation. And I don’t know if you get any folks, but do you have any folks that have… are they EMF sensitive? Dr. Deb Muth 00:25:16 Oh yeah, we have a whole bunch of them. Bob Miller 00:25:18 Yeah, and then if you have any TBIs, So, plenty of things here. that will stimulate into the microglia, M1. Now, you could say, well. We’re all pretty much exposed to the same thing. Why do some people get hit harder than others? So here’s where we’re gonna start. There’s an enzyme called Nrf2 and RF2. And Nrf2 is the enzyme that senses when there’s inflammation. And turns on hundreds of anti-inflammatory enzymes. We’ll show when we do the demo, you can have genetic weakness on NERF2. And NERF2 inhibits and slows down microglia M1. supports M2. Now, if it’s not complicated enough, there’s an enzyme called KEEP1. And KEEP1 inhibits NRF2. And you can actually have gain of function on keep 1, that makes Keap 1 stronger. So… A lot of the people who land on my doorstep So… A lot of the people who land on my doorstep Both parents gave a mutation on KEEP1, making it overactive. Both parents gave a mutation on KEEP1, making it overactive. Dr. Deb Muth 00:26:31 Hmm. Dr. Deb Muth 00:26:31 Hmm. Bob Miller 00:26:32 Suppressing Nrf2, nerve 2 might be weak. So, nobody’s putting the brakes on, M1. And by the same token, Nerve 2 supports M2. Then there’s a process called mTOR and autophagy. mTOR stands for mammalian tard of rapamycin, the growth of new cells. And then autophagy, taking our dead cells and recycling them. We need a balance between the two of them. If we didn’t have mTOR, the sperm and the egg would never become the baby, the baby would never become the adult, we wouldn’t make new cells. But our cells are constantly, you know, the old cells dying off. Autophagy is where we take that debris from the cell and recycle it, just like a farmer Plows the crop under at the end of the year. The dead plant then becomes the fuel for the spring, your dead cell becomes the fuel for the spring, and that’s autophagy. So we’re gonna look back someday and say, what were we thinking? We give our animals growth hormones so they get fatter faster. Oh my. So, we consume those animals, and inventory runs faster. Now, for anybody who’s, You know, maybe above 40, 45 years old. Think back when you were 12, and what did girls look like? They were primarily flat-chested little girls. Now they look like 16-year-olds. Because environmentally, we’re jacking up mTOR. So, mTOR stimulates microglia M1, suppresses microglia M2. Probably 80% of the folks we visit with. This is the part of the problem. NRF2 is weak. mTOR is strong. Environmental factors come along. And this guy gets carried away. He doesn’t do that burst and move back. Stays here. We’re calling that How environmental factors create a locked-in, pro-inflammatory. and neurotoxic phenotype. In other words, once it starts, it just keeps… Feeding upon itself. Alright, so what happens now when microglia is overactive. it triggers these 3 enzymes, TNFA, N of kappa B, And interleukin-6. Each one of these can have genetics that make them run stronger. Then it stimulates an enzyme called NLRP3, Which makes what are called inflammasomes. Now, guess what inflammasomes can be? Your best friend or your worst enemy? Because they will, if you’ve got, again, a virus or bacteria, or possibly even some bad cells in the body. They will zap them. Well, that’s good. Unless it’s overactive. Unless it’s overactive. And then what it does, through interleukin-1 beta, makes excess glutamate. And then what it does, through interleukin-1 beta, makes excess glutamate. Anxiety, gut inflammation, OCD, ADD, autism. And, you know, glutamate, we’ll talk about that a little bit, but glutamate makes you intelligent, highly motivated go-getter. but can also be excitatory. And then, look what it does. Let’s see, do I have the drawing tool here? Yes, I do. Okay. So, it comes down through here, Makes the glutamate. Comes back up through here. through the ADORA 2A enzyme, Then we’ve got a feedback loop that feeds upon itself. Then, through interleukin-18, we make histamine. and mast cells. And then through histamine receptor site number 1, we come back and spin it. And now you’ve just got this spinning feedback loop. So, the glutamate will make you anxious, the histamine will give you allergies and make you anxious. And you’re allergic to everything, and you’re feeling horrible. Now, it doesn’t end there, Dr. Dad. It then goes on to make something called gast dermins that creates pyroptosis, where it actually starts punching a hole in the cell membrane. And you’re only going to be as healthy as your cells are. Just a little background. You know, we’re made up of trillions of cells, and each one of them has what’s called a lipid bilayer, made from lipids, which comes from fats. And you’re only going to be as healthy as those membranes are. So that’s why we coined an interesting phrase. Cellular CPR. Construct the cell. Protect the cell. And restore the cell membrane. And we believe that’s going to be revolutionary in the functional medicine world. So… It’s not hard to figure out that if you start punching holes in the cell membrane, that’s not a good thing, okay? Bob Miller 00:31:22 Now… There’s an interesting molecule called NAD. Thicotide adenoside dinucleotide. And anybody who’s in the, you know, listening to the health podcasts and things, they’re… They’re, they’re learning about NAD. And I’m going to show you a chart later, all the good things that NAD does, but For the most part, it helps what’s called sirtuins. And sirtuins are quite interesting. If anybody’s looking at longevity. The sirtuins is where they’re looking at.Because sirtuins turn on good things. Turn off bad things. And I’ll show some charts on that later. So for right here, this sirtuin uses NAD, to slow down NF-kappa-B. CERT 2 uses NAD to slow down an ORP3. So, if we’ve got genetic weakness on these, or we don’t have enough NAD, We don’t hold this pathway back. Make sense? Dr. Deb Muth 00:32:24 Yeah, makes perfect sense. Bob Miller 00:32:25 Now, I’ll show this a little bit later. So, people are like, oh, well, I’m gonna start taking some NAD. Dr. Deb Muth 00:32:31 Right. Bob Miller 00:32:32 And there’s functional doctors who give NAD intravenous. It was just this morning, I was talking to a woman who said, Oh my gosh. I went and got intravenous NAD, and it took me a month to recover from that. Dr. Deb Muth 00:32:45 Hmm. Bob Miller 00:32:46 what happens is, and I’ll show this in a little more detail, there’s an enzyme called CD38, that’s stimulated by NF-kappa-B. And it takes NAD, To make intracellular calcium. that stimulates NLRP3 and actually makes things worse. So, if we have this guy upregulated, and I’ll show a chart what does that. taking NAD will make you worse. Again, when I go into the software, I’ll show you that whole pathway, so… I would encourage people, you know, just don’t go out and start taking massive amounts of NAD, you know, stick your toe in the water, see how you do. Because everything you’ve heard about, how good it is, is true, unless this guy says, oh, thank you very much, let me make more inflammation. Now, this might be part of our innate immune system, that if we have some pathogen that’s gonna kill us. By golly, we want that to happen. But if this is happening by environmental factors, Then it’s detrimental. So the immune system that protected us a thousand years ago now might be turning on us because of the environmental factors that we showed earlier. All right. Then there’s an enzyme called PARP that’s NAD-dependent, and that actually repairs strain breaks in your DNA. Now, the next thing that happens… is there’s an enzyme called NADPH oxidase that gets stimulated. and something called INOS. Now, I’m sure most people know about nitric oxide. It’s a gas that dilates your blood vessels. That’s why sometimes they’ll even give people drugs, nitroglycerin, to boost their nitric oxide. That’s why people are doing beetroots and other things to boost their nitric oxide. But there’s an OS3 enzyme that makes the nitric oxide that’s good for blood flow. But there’s an INOS That makes nitric oxide to kill pathogens. probably might be the third or fourth time I’ve said this. That’s a good thing, unless it isn’t. So, if it’s killing some pathogen, great. It was just misfiring. it combines… With superoxide that’s made by this enzyme, and makes something called peroxynitrite, which is one nasty free radical that chews you up and spits you out. So, the NOx enzyme, NADPH oxidase, uses NADPH, To make this free radical called superoxide. If we have time, we’ll get into it. NADPH is what your body needs to recycle your antioxidants.So, I coined the phrase, the NADPH steel. Where the NOX enzyme takes this very important NADPH, And rather than being useful, makes superoxide. Now, again, is that fine if you’ve got some bacteria to kill? Of course. But if it’s just chronically running, it’s just making all this chronic inflammation. Then it makes something called hydrogen peroxide. And we need to clear hydrogen peroxide by 3 enzymes, catalase, thyroid reduction. And glutathione peroxidase. If we have genetic issues on here, or we don’t have the cofactors. There’s something called the Fenton reaction, discovered in 1895 by Dr. Fenton. Where hydrogen peroxide combines with iron to make what are called hydroxyl radicals. And guess what they do? They create lipid peroxides, That damages your cell membranes. Now, again, the body’s pretty darn amazing. We have glutathione, And here’s where your body’s taking glutathione and recycling it. But look who’s needed to recycle it. NADPH. So, if this guy up here is chewing it up, We don’t recycle our glutathione. And then an enzyme called glufon peroxidase 4, Takes this damaged lipid and repairs it. So, here we’ve got this protecting, we want to protect it by not having this happen. But then we also need this guy to do the restoration. So, there’s a lot that can go wrong in here, Dr. Deb. Dr. Deb Muth 00:37:07 There’s a lot that could go wrong. And I can imagine some of my listeners are thinking that lipid peroxidase, is that the same thing as what they’re thinking of when we talk about lipids and cholesterol? Is that the same process that’s happening there? Bob Miller 00:37:22 Well, no, no, the lipids can be used to make cholesterol, but here we’re talking about where they’re going to build the cell membrane. And they’re being… and they’re being, destroyed. If anybody would like to see a visual representation of this, just go on YouTube. And type in, ferrooptosis Animation. cool little video, it’s about 3 minutes long, and it shows the lipids coming over, being oxidized, and now GPX4 fixes them, so… YouTube, Pharaoptosis Animation, cute little video. It’s just that really… Shows vividly what we’re… what we’re talking about here. Now, this is… Dr. Deb Muth 00:37:59 And so this is very common, too. Like, a lot of people do hydrogen peroxide IVs. Dr. Deb Muth 00:38:04 And so, if somebody doesn’t know their genetics, they could have a problem with doing those, just like they could doing the NADHIVs, correct? Bob Miller 00:38:13 Sure, yeah, yeah, yeah. So, I’ve talked to so many, you know, of course, the hydrogen peroxide kills pathogens. I mean, that’s what it does. So… but I’ve spoken to so many people that said. I had one client that said they’ve never been the same after having one hydrogen peroxide infusion. Dr. Deb Muth 00:38:30 Interesting. Bob Miller 00:38:31 Yeah. So… it can be… I see why people use it, because it. Bob Miller 00:38:36 pathogens, But on the other hand. And now’s a good time to speak about… I don’t have it on here, but there’s a, there’s an enzyme called the HFE gene. And that is what causes you to absorb iron. And there’s mutations in it that cause something called hemochromatosis. Were you overabsorb iron? Now, true hemochromatosis is when both parents give you a mutation. But there’s now growing evidence even a heterozygous can cause a little bit more iron absorption, not to the human chromatosis point, but overabsorption. So, if you overabsorb iron, And you have too much hydrogen peroxide that’s not cleared, All kinds of inflammation. Now, what’s happened is sometimes this inflammation Will damage the red blood cells. And some well-meaning doctor says, oh, you need some iron. And they take iron and it makes it worse. So, can’t tell you how many people I’ve said, you’ve got the overabsorption of iron, and they say, well, that can’t be right, because I’m low in iron. Well, that could be because it’s being chewed up here. Dr. Deb Muth 00:39:40 Sure. GPX1 and TXN turn it into, to water. The, catalase turns it into water and oxygen. Dr. Deb Muth 00:39:58 Now, I see a lot of my clients who have mutations or SNPs on that GPX gene, on that glutathione gene. And they really struggle to clear a lot of their toxins. Bob Miller 00:40:12 Sure. Dr. Deb Muth 00:40:14 Yeah, absolutely. Well, GPX4. Bob Miller 00:40:18 is what, repairs, but you can see GPX1 Is what uses glutathione. To turn hydrogen peroxide. So, but it all depends upon having enough glutathione. Dr. Deb Muth 00:40:30 Yeah. Bob Miller 00:40:31 Well, guess who controls making a glutathione? Dr. Deb Muth 00:40:34 Nerf 2. Bob Miller 00:40:37 So, if you have a keep one weakness, or strength to two… I’m sorry, keep one is too strong. Nrf2 is too weak. You don’t make glutathione. So, when a lot of people do that, it’s like, well, I’m gonna take glutathione. Dr. Deb Muth 00:40:51 Right. Bob Miller 00:40:52 And some do great, and some do poorly. You know, because… and I’ll show this on one of the other charts. You can see here that the, The glutathione has to be recycled. And if we don’t recycle it, it actually turns into superoxide free radical. So… NADPH are the cofactors, For taking the oxidi… here’s oxidized glutathione, here’s reduced. So, this is a good glutathione. After it does its job, you can see it becomes oxidized.We need to recycle it. Well, if we have weakness on the enzyme that does that, or a weakness in Nrf2, or not enough NADPH. The oxidized glutathione never gets recycled. So, I’ve talked to a lot of people who said, oh, glutathione made me so sick, and say, well. Dr. Deb Muth 00:41:43 Yeah. Bob Miller 00:41:44 You need it, but you need to recycle it. Dr. Deb Muth 00:41:46 Can you speak for just a brief moment, too, about MTHFR? That is a very popular gene, it’s all over social media as the major gene, but can you speak to a little bit about that, and how that fits into this whole process of things? Because it is just such a small piece. Dr. Deb Muth 00:42:04 understanding genetics. Bob Miller 00:42:06 Yeah, to be honest, it drives me nuts. Dr. Deb Muth 00:42:08 Me too. Bob Miller 00:42:11 Alright, so… You know, there are people on social media I won’t say what I think, I’ll be kind. But… But the, And, you know, they might mean well. But they talk about, if you have MTHFR and COMT and PEMT, that’s… oh my goodness, that’s horrible, and we’ll fix that for you, and you’ll be fine. Bob Miller 00:42:36 it just irritates me to no end. And it really could get anybody who’s doing this legitimately in trouble. I mean, I’m afraid someday, you know, there might be some cracking down on this kind of nonsense. Now, to answer your question about MTHFR. Dr. Deb Muth 00:42:51 I mean, it really is, but I’ll tell you what, why don’t we hold that thought until I go to another map and I can actually… Okay. Bob Miller 00:42:56 But the real… the cliff notes is the MTHFR puts a methyl group on your folate, which is needed, but it has gotten way, way, way too much attention. And people learn they have MTHFR, and they start taking a multivitamin with methylfolate, then they take a B vitamin with methylfolate. Dr. Deb Muth 00:43:13 And they’re pushing it too hard. Bob Miller 00:43:15 Yeah. So I can’t tell you how many people I’ve helped by saying, stop it. Dr. Deb Muth 00:43:20 Yeah, take less of it. Bob Miller 00:43:21 Take less of it, yeah. So, yeah. Yeah, there’s a… If somebody, say, ranked the enzymes at their level of importance, MTHFR might be 40 or 50 on a scale of 100, you know. Keep one Nerf two. big deals. Dr. Deb Muth 00:43:40 deals. Bob Miller 00:43:41 NQO1 that I didn’t even talk about yet, NQO1, takes your, NA… your NAD goes into NADH, To make electrons for the electron transport chain. you need NQ01 to bring that back. If that’s not working, and I’ll show you on the NAD map how disastrous that can be. Now, the next piece is here, and I think You know, if you talk to any school teachers and say, if you’ve taught for more than 10 years, how are the kids today? Every one of them says, more ADD, ADHD, more autism. Just look at human beings, we’ve never been so agitated. You know, everybody, and it might be a social media thing, but people take a position on something, and if anybody doesn’t share that position, they view them as the enemy. Dr. Deb Muth 00:44:29 And it’s kind of scary what’s happening to us. Bob Miller 00:44:33 So, we can’t agree to disagree anymore. We see anybody who has a differing opinion as the enemy. And, you know, there was… there’s people that didn’t have Christmas dinners together, because they had political differences, like… Dr. Deb Muth 00:44:44 Excuse me. Bob Miller 00:44:45 can’t you put your political differences aside to have Christmas together, you know? Dr. Deb Muth 00:44:49 Right? Bob Miller 00:44:50 become that, you know, no matter what your position is, and I’m not saying anyone’s right or wrong, I’m just saying. You know, in the old days, they used to say that the Republicans and Democrats in Congress would argue policy and then go have dinner together. And now everybody’s all up in arms, angry. Dr. Deb Muth 00:45:05 Yeah. Bob Miller 00:45:06 So… There’s likely multiple reasons for that. But let me show you one of them. That, you know, to what degree this is… very important, we don’t know, but I think We’re beginning to believe this is very important. So, there’s something… there’s a neurotransmitter called GABA. And God buys the don’t worry, relax, be happy. Chill. Okay. Dr. Deb Muth 00:45:31 Nobody has enough of that anymore. Bob Miller 00:45:33 Well, yeah, you’ll be surprised what I’m gonna show you. So, let me see if I can find a, Let me see if I can find the right slide here. Let me look for it here. So, there’s something called a GABA receptor site. And here you can see… This is a neuron, and this is where you, The neuron normally is excitatory. However, there’s normally low chloride in the neuron. Dr. Deb Muth 00:46:09 Hmm. Bob Miller 00:46:10 So, GABA itself is neither relaxing. For excitatory, all GABA does, it opens up what’s called a chloride channel. And then chloride, which has a negative charge, will flow into the neuron. Follow me there? Dr. Deb Muth 00:46:26 Yep. Bob Miller 00:46:27 And as it does, it changes this from a positive charge to a negative charge, And it’s relaxing. and inhibitory. Dr. Deb Muth 00:46:34 Hmm. Bob Miller 00:46:36 Now, on the other hand, there’s enzymes called NKCC1, That will push chloride in. and KCC2 that will bring chlor… oops and bring chloride out. And then there’s a sodium channel. And, sodium has a positive charge. And glutamate will push that in. So, as long as this is happening. And GABA says, receptor sites, open, chloride goes in, Chill. However, If NKCC1 Pushes extra chloride in. KCC2 doesn’t pull it out. and GABA hits the receptor site, the GABA comes flowing out, Sodium comes in, And now it’s excitatory. So Gabba didn’t change. GABA just opened the receptor site, that’s all it does. Dr. Deb Muth 00:47:33 Yeah. Bob Miller 00:47:34 But it’s the chloride balance that’s going to determine whether this is relaxing or not. Now, these are the things that go along with when they lose that KCC2 or gain NKCC1. Pain and sensitivity, burning electrical, neuropathic pain. Normal touch hurts. Sound and light sensitivity. Tinnitus can flare. Headaches and migraines. Seizure tendency. Body jolts. Spasticity, cramps, stiffness, startle reflex. Trouble falling asleep, non-restorative sleep. Anxiety, stress, reactivity, that’s what we have now. Hyperarousal, panic-like surges, irritability, racing thoughts. Brain fog, slowed processing, working memory slip-ups. Mental fatigue. Episodes of racing hearts, sweaty palms, guts on edge. Those are all the things that happen when this GABA switch occurs. Now, here’s what happens, and this is what I’m going to be presenting at an autism conference. When you have a newborn, they need that NKCC dominant to develop. By early childhood, it should… or, sorry, early adulthood. we should move over to the KCC dominant, that’s the taking the chloride out. Nice-looking 25-year-old boys, functioning very well. However, when we get microglia M1 upregulated. Because of environmental toxins, processed foods, Tylenol, aluminum. they stay in NKCC1 dominant, and there’s ADD, ADHD, Autism, the whole spectrum. because… They’ve not moved over to the… They’ve not moved over to the KCC2. And again, this is caused by… Environmental factors. Stimulating the microglia. And then, interleukin-1, interleukin-18 weakens KCC2, interleukin-1 beta, Strengthens NKCC1. high chloride. We open up the chloride channel, In Rebell Excitatory. So, I think when, When the pediatricians get ahold of this, they’re going to be very excited to know that This could be why we’re seeing such a rise, and not just autism, but ADD, ADHD, anxiety, the whole shit mess. Dr. Deb Muth 00:49:58 thing. Bob Miller 00:49:59 Yeah, so… and you can see NF-kappa-B stimulates that. These stimulate it, and I think that’s why everyone’s getting so anxious. Now, there’s a little bit more to it, and we’ll get into this when we look at some of the maps, but… The, the glutamate, Which is excitatory. will stimulate the NMDA receptor, make more glutamate, And glutamate will inhibit KCC2. And then we also need an astrocyte To, take both ammonia And glutamate, and… Turn them back into glutamine. And I’m going to talk to you a little bit about arachidenic acid, and if we have too much arachidenic acid. or TNFA is upregulated, that doesn’t happen. Ammonia goes up, and there may be multiple reasons for this, but this is a reason why some of the autistic kids do flapping. Dr. Deb Muth 00:50:49 Hmm. Bob Miller 00:50:50 Because they’re not clearing their ammonia. And you can tell if somebody has high ammonia by… they get that old person smell, you know. Dr. Deb Muth 00:51:00 Yup. Bob Miller 00:51:01 your vehicle cycle’s not taking out the, the ammonia. Now, last pathway here. There’s growing interest in mast cell activation. So, back here, we talked about peroxynitride. And that will stimulate mast cells, and those are white blood cells that are your best friend, unless they’re your worst enemy. Then it’ll make histamine. And there’s enzymes called histidine decarboxylase that’ll make more. Dr. Deb Muth 00:51:28 I’m sure everybody’s heard of DAO, the enzyme that degrades histamine. Yep. Bob Miller 00:51:31 We can have genetic weakness, we don’t make that. There’s an enzyme called histamine and methyltransferase, That, That breaks down the histamine. Then if we don’t do that, it’ll get stuck in the histamine receptor site. And then it’ll make something called, renin. Which will cause angiotensinogen to turn into angiotensin. One, that turns into angiotensin II,And that’s where people make aldosterone, where they’ll get the, The swollen ankles and high blood pressure. But interestingly, there’s an enzyme called ACE2, that takes this guy and turns it into angiotensin 1-7, Which is anti-inflammatory and also inhibits… TNFA. Now, you can have weakness on ACE2, But… and anybody’s saying, that sounds familiar? Dr. Deb Muth 00:52:25 That’s where COVID comes in, using ACE2. Bob Miller 00:52:28 And now we just found there’s literature that if you get COVID long enough, it can actually make ACE2 not be able to work as well. So look what it does. It comes down here, stimulates the NADPH oxidase, More superoxide. More peroxynitrite. And we’re on a cycle here. We’ve actually named this the Home Cycle Hypothesis, the proposed feed-forward loop. That just keeps feeding on itself. All being caused by… Primarily, The environmental factors. But hitting those who have genetic weakness the hardest. That’s why. Dr. Deb Muth 00:53:08 To the people. Bob Miller 00:53:09 Don’t live in a moldy house. One person is sick as can be, and the other person says, well, you must be imagining things, because I don’t feel anything. Dr. Deb Muth Yeah. Same thing with long haul, right? Two people can both get sick, one gets sick and never seems to recover, and somebody else gets sick, and they have absolutely no problems with it at all. Bob Miller 00:53:30 Sure. Well, think about it, if you get COVID, and ACE2 is weak, and some of this other stuff is going on. This thing just starts feeding upon itself. Dr. Deb Muth 00:53:38 Keep creating more inflammation, more complications, nothing’s calming down. Bob Miller 00:53:43 Yeah. Now, you, you ask about, MTHFR. So, this is the, this is the, the software called Functional Genomic Analysis. There’s a demo report we have. So, let’s talk a little bit about, MTHFR. So, we actually have a map called a methylation map. Now, what happens is, when you do your saliva test, you, you know, you spit, you put some saliva. in a collection kit, goes to a lab, takes out the DNA data, sends it to the computer, and now you can actually see it visually. Okay. So, it’s gonna take a second for this, data to load up, it’s, and each of these Circles, each of these ovals, is an enzyme. And the data gets loaded up to see where it is. So, until it gets loaded up here, I didn’t preload this. There it goes. So… The primary thing about methylation is There’s a nasty substance called homocysteine that, if it’s too high, can really be detrimental. The body takes methylfolate, and combines with methyl B12, To bring this back up to methionine. And then through the MAT genes, we make SAMI, S-adml methionine. Which is involved in so many processes. Then after it does its thing, it turns back into homocysteine. And this thing needs to keep spinning around. That’s why, you know, it’s a good idea to keep homocysteine at, do you have a number that you’d like? 7, 8? What do you like for a number? Dr. Deb Muth 00:55:24 Yeah, I like mine below 7. Bob Miller 00:55:26 Yeah. So if the homocysteine goes too high. It, caused all kinds of problems. So, here’s where you ask about the MTHFR. So, here you can see on this individual. I click on MTHFR, and you can see it comes up here, here’s the C677. And you can see here where it says, variants. I’ll… I’ll draw in case somebody’s having a hard time seeing that. So, you can see there’s nothing in there. That means there’s no genetic mutations. If one parent would have given a mutation, there’d be a 1. If both parents did, there’d be a 2. Now, here’s why Yes, methylation is important, I’m not saying it isn’t important, but look at this MTHFRC677. In my software. Only 42.5% of the population does not have a mutation. 44.7% have won. 12.9 have 2. So, this isn’t some rare, oh my god, I’m gonna die… Kind of thing, yeah. Dr. Deb Muth 00:56:27 Right. Bob Miller 00:56:28 So, And then what happens is that, and again, I’m not dismissing methylation, I… we could do a whole show on methylation. Bob Miller 00:56:36 get it. But I think that what people are doing is they’re, they’re learning about MTHFR, they get it measured, they panic. They start taking massive amounts of methylfolate, which many times is to their detriment. Dr. Deb Muth 00:56:50 Well, it’s… and isn’t it true, too, with MTHFR, like, you have to also look at MTR, MTRR, and the more we stack up of those, the more complicated than MTHFR can be. It’s not… it’s not as simple as just saying MTHFR 677 versus 1298. It’s more complex than that, kind of like what you’ve already shown with some of the other things. There’s more to it than just that one little sliver. Bob Miller 00:57:17 Oh, sure, well, let’s take a look. So, remember I said there’s a cofactor? One of the cofactors is called FAD. Just a Bob Miller observation, that’s all. But when people have trouble with their riboflavin and they don’t have enough FAD, They’re doing much worse than people who have just a C677. So, right here, you could have perfect C677th. And if you don’t have the cofactor, it’s not gonna work, okay? Dr. Deb Muth 00:57:48 And as you said, there’s an MTR enzyme. Bob Miller 00:57:51 that takes methylfolate and methyl B12, to spin it around. So, here on this individual. here’s your… here’s your B vitamins, or I’m sorry, your B12s. There’s an enzyme called TCN1 that takes it from the stomach into the blood. Then there’s other enzymes that take it from the blood into the tissue. And if you’re having trouble here. Well, then you’re not going to have this working, so… Even if you don’t have MTHFR, And you have MTR, like this, no, I’m sorry, this person doesn’t. But they have the MTRR, and then they don’t have enough B12, this isn’t gonna work, aside from that. And then there’s a middle pathway. And then there’s enzymes called the MAT1. they take the methionine to the salmon. If that’s not working, we stick… we get stuck in methionine. So, it’s, it’s not just an MTHFR. And then, one of the things that people forget about. is through these CBS enzymes and CTH, We make cysteine, which is needed to make glutathione. The master antioxidant. So, it really is that… I call it the, The 3D chess game played underwater. Dr. Deb Muth 00:59:07 It really is. I mean, I see people who have CVS, COMT, glutathione, MGHFR genes. And some of them function just fine. Like, they have Like, I look at this person and I’m like, oh my gosh, I don’t know how they’re functioning because they’re double mutated on so many pathways, but yet they don’t have a lot of symptoms, they don’t have a lot of complications. Somehow their body has figured out a way to adapt to what it has so it can stay alive and it can function at a high functioning level. Bob Miller 00:59:36 Yeah, and they may be, you know, eating right? Yeah. Staying out of a moldy house. reducing stress. So, it’s diet, it’s stress, it’s genetics, environmental factors. So, yeah, we can’t just say somebody’s gonna be good or somebody’s gonna be bad. You know, some people get scared, oh, I got all these, it’s like, well… Bob Miller 00:59:56 Are you living in a moldy house? You know, and if you live in a moldy house and your glucuronidation pathway doesn’t do well, or if you’re, you know, a smoker, or you’re constantly eating junk food, I mean, all. Bob Miller 01:00:07 things come together. Although, you know, when we focus on genetics, we’re well aware that this is just a piece of it. You know, you could have identical twins, Genetically, and if one… Is exposed to mold and smokes and drinks and stressed out. They’re gonna be a whole lot sicker than their sibling. Bob Miller 01:00:28 Yep. Dr. Deb Muth 01:00:29 Yeah, it’s that concept of taking twins, and one gets raced with one family, and one gets raced with another family, and they don’t have the same… problems that… that each other have, you know? It’s a very unique situation, we don’t think about that enough. Bob Miller 01:00:44 Alright, so again, genetics loads the gun, environment pulls the trigger. So, if you’ve got a loaded gun, but you don’t have the triggers, you’re okay. Dr. Deb Muth 01:00:53 Yeah. Bob Miller 01:00:54 Yeah. So, remember I said I was going to talk about NAD? So, here’s NAD, and what it does, it turns into NADH. And what NADH does, it, Comes down this pathway, what’s called the electron transport chain. And that makes your ATP, that’s your energy. So, if this wasn’t working, we wouldn’t be alive, because we wouldn’t have energy. So it donates an electron, that’s why it’s called electron transport chain. So, we need NAD, To make this, to make the energy. But remember I said that NQ01, this would probably be, like, on my top 10 list of… Bob Miller 01:01:36 Much more important than MTHFR. This one takes NADH back to NAD. If we’re stuck over here, We’re low in this NAD+, But what happens is, NQO1 also provides CoQ10. And CoQ10 Is what’s needed for the electron transport chain to flow. So if we get too many electrons up here. And they don’t turn them into energy. They make a nasty free radical called superoxide. Okay. Now, NAD plus also makes NADPH, And that is needed. Remember I said we need to recycle our antioxidants. So, if we have a problem with FAD from riboflavin. Yeah, we don’t have enough NADPH, Glutathione’s not getting recycled, and you’re gonna be inflamed. And you take glutathione, you’ll feel worse. There’s another enzyme called thimoredoxin. Same thing, needs NADPH and FAD. And same way with your nitric oxide, there’s an enzyme called NOS3, That makes the nitric oxide that dilates your blood vessels. And if we don’t have enough NADPH or fat, You’re gonna make superoxide. Rather than nitric oxide. Now, remember

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ACCESS THE FREE GUIDED SESSION "Why Spanish Feels Hard and It's Not You": https://thespanishontheroad.com/spanish-for-neurospicy-brains/Does practicing Spanish in traditional academies feel completely overwhelming? Does your brain literally shut its blinds halfway through a class, or do you feel like you've completely blown a fuse after a video call?

In tonight's sleep hypnosis with Jessica, we explore ADHD with compassion and curiosity, discovering how relaxation can help guide attention more easily. As you drift across a calm ocean, you'll learn to work with your mind's natural rhythms, finding focus, balance, and rest along the way. As always, tonight's episode will start with a relaxing introduction from Jessica, before we sink into tonight's Sleep Hypnosis. If you'd like an extra immersive experience, you can also watch this episode on Spotify, complete with soothing visuals

When he was young, it seemed like my son Cooper was almost always active and agitated. I tried everything I was told to try - bubble blowing for deep breathing, emotion naming, zones of regulation, nature walks with candy as incentives - but nothing worked. Maybe the activity would occupy him once, but then he'd be agitated all over again afterwards. I thought I must be going it wrong, or just a bad mom.What I know now is that I wasn't and I'm not - and neither are you. The logic underneath those approaches just does not match how a pathologically demand avoidant nervous system actually works.In this episode I discuss the 4-S Framework I developed to help my PDA son - and the children of the many families I was working with - stay regulated. The four S's are: safe nervous system, sensory intense experience with novelty and dopamine, screens, and special interests. I talk through what each one means for a PDA brain specifically, why children in burnout can often only access some of the four, and how to use this framework to structure unstructured time so it feels less like chaos and more like a plan.Key Takeaways Why the Approaches I Was Given Kept Making Things Worse | 00:02:06 I walk through the regulation strategies I tried with Cooper before I understood PDA: sensory integration activities like bubble blowing and glitter shaker bottles, naming emotions and using the zones of regulation stoplight, and nature walks I would incentivize with sweets. Each one followed the same pattern: novelty made the first attempt work, and the second produced refusal, avoidance, or escalating behavior. But then I had an "aha" moment and made a shift that changed everything. S1: What Actually Makes a Nervous System Safe for a PDA Brain | 00:21:43 A safe nervous system for a pathologically demand avoidant child is not simply a kind or emotionally attuned person. In my work with thousands of families, I have seen loving, competent, well-trained adults be deeply unsafe nervous systems for PDA children, not because they are unkind but because they arrive with an agenda. They want to teach, engage, improve, or modify. The safest nervous system is the one that is not trying to change the child at all. I use the example of a grandma who arrives with activities and baking plans versus a grandpa who sits on the couch reading his phone with zero agenda. The PDA child will reliably gravitate toward grandpa. This is also why you may notice your child feels safer with your partner on certain days, or with a teenage neighbor who just wants to jump on the trampoline without any goal. The lower the agenda, the safer the nervous system. S2: Sensory Intense Experience, Novelty, Dopamine, and the Modern Day Alchemist | 00:26:48 The second S covers three overlapping things: physical sensory intensity like roughhousing; novelty, which is why the first time at an ice skating rink produces full regulation and the second visit produces a meltdown; and dopamine, which can show up as a fixation on sugar, screens, or the drive to transform things from one material state to another. I call this last pattern the modern day alchemist, and I see it consistently across PDA children and adults I work with. S3: Screens, Books, Podcasts, and Journaling as Regulation Tools | 00:40:02 I view screens neutrally, and I want to be clear that this S is not only about screens. For PDA children and teens who are older, or for PDA adults who grew up before constant access to devices, this S may have looked like always having a book in hand, listening to podcasts, or journaling compulsively. What all of these have in common is that they provide autonomy, allow engagement with special interests and learning without an agenda, and offer relief from the intense sensory input that comes both from the outside world and from inside a nervous system that is chronically activated. For Cooper during burnout, screens were one of only two things that kept him regulated enough to eat and exist. Now that his activation has come down, he tracks his own screen time and averages around two hours a day, half the national average for American children. That shift was not something I imposed. It happened naturally as his window of tolerance expanded. I share this because I know how much shame parents carry around screen time, and I want to offer a different frame: screens in the right season can be what keeps your child accessible to life. S4: Special Interest and How to Use the Full Framework in Practice | 00:43:45 Special interest for a PDA brain involves what researchers call monotropic focus: sustained attention toward an interest that is deeply regulating, and dysregulation when pulled away from it. For Cooper right now the three special interests are football, fishing, and friends. When I need to help him out of the "I'm bored" loop, I use the framework to identify which S's are available and stack them. In the episode I also name what this looks like in burnout: during the hardest years, Cooper could only access safe nervous system and screens. The other S's returned as his activation came down, and I want parents to hold that as evidence that things can shift.Relevant Resources Understanding PDA — Free class where I teach the nervous system disability framework and the threat perception mechanism that explains why standard regulation approaches tend to backfire for PDA childrenBurnout — Free class with context for the burnout period I describe in this episode, when only two of the four S's are typically accessibleSchool, Screens and Siblings — Free class directly relevant to the screens S and how I think about screen time as a neutral tool within the Four S Framework Monotropism: Understanding Autistic Ways of Being — Background reading on the monotropic focus I describe in the S4 section and how it shapes regulation and learning in autistic and PDA brainsMonotropic Split and Burnout — Explains what happens when monotropic focus is repeatedly fractured, directly relevant to why pulling a PDA child away from a special interest contributes to cumulative activation and burnoutMe and Monotropism: A Unified Theory of Autism — Deeper academic context for the monotropism framework I reference when explaining the fourth S

Send us Fan MailSend us Fan MailIn this compelling episode of Living the Dream with Curveball, we welcome Tony Brussat, a thought leader dedicated to helping individuals rethink their connections in a world rife with addiction. Tony delves into the pervasive nature of addiction, not just limited to substances but extending to screens, food, and consumerism. He introduces the concept of "Qualia," the sensory experiences that shape our reality, and discusses how our relationship with these experiences can influence our daily decisions.Tony shares his journey, from a background in English literature and nursing to exploring the transformative power of rituals. He emphasizes the importance of separating from routine to engage meaningfully with our senses, allowing for reflection and deeper understanding of our desires versus our needs. Through anecdotes and insights, he illustrates how recognizing and appreciating the Qualia in our lives can combat the cycle of addiction and foster a more fulfilling existence.Listeners will learn about the distinctions between different types of dopamine, the dangers of unnoticed addictions, and practical strategies for integrating ritual into daily life to enhance mindfulness and connection. This episode is a thought-provoking exploration of how we can reclaim our attention and reshape our lives away from addiction towards a more meaningful existence.What You'll Learn in This Episode:- The concept of Qualia and its significance in our daily lives- How addiction manifests beyond substances- The role of rituals in fostering mindfulness and reflection- Insights into the human economy and its relationship with desire- Practical exercises to incorporate Qualia into your daily routineFor more information on Tony Brussett and his work, visit www.planetqualia.com and check out his YouTube channel at Planet Qualia.Support the show

Episode 398 revisits neuroscientist Friederike Fabritius (from November 2022) to explain how three ingredients — fun (dopamine), fear (productive challenge), and focus — create the neurochemical conditions for sustained motivation and flow. You'll also learn why individual neurosignatures matter and how designing environments that match your brain, rather than forcing yourself to change, makes effort easier and motivation durable. Welcome back to Season 15 of the Neuroscience Meets Social and Emotional Learning Podcast. I'm Andrea Samadi, and on this podcast, we bridge the science behind social and emotional learning, emotional intelligence, and practical neuroscience so we can create measurable improvements in well-being, achievement, productivity, and results. In This Episode 398, Closing the Motivation Loop, with Friederike Fabritius, We Will Cover: ✔ How FUN, FEAR, and FOCUS create the neurochemical conditions for sustainable motivation ✔ Why dopamine is more than a pleasure chemical—and how it fuels motivation, anticipation, effort, and reinforcement ✔ How FUN creates dopamine and keeps us engaged in meaningful work ✔ Why the right amount of FEAR (challenge) drives growth without causing burnout ✔ How FOCUS converts energy, attention, and motivation into measurable results ✔ The connection between FUN, FEAR, FOCUS, and the Motivation Loop ✔ Why different brains require different motivation strategies ✔ Understanding your unique "Neurosignature" and how it influences performance ✔ How dopamine interacts with other neurochemicals like testosterone, estrogen, serotonin, and oxytocin ✔ Why sustainable motivation begins with self-awareness ✔ The Stress vs. Performance Curve and finding your optimal challenge zone ✔ How under-challenge leads to boredom and over-challenge leads to burnout ✔ Why peak performance occurs when challenge matches your brain's needs ✔ How to design environments that support attention, motivation, and performance ✔ Why the strongest motivation loops are powered by alignment—not willpower ✔ Practical strategies to create the conditions where your brain naturally wants to engage and perform ✔ How self-awareness, energy management, and neurochemistry work together to sustain long-term success ✔ What keeps the Motivation Loop repeating—and what causes it to break ✔ How to close Phase 2: Neurochemistry & Motivation and prepare for Phase 3: Movement, Learning & Cognition

Beloved, In an age shaped by speed, endless distractions, and accelerating tech dominance, rising loneliness and disconnection have become defining conditions of life.

Summary Discover the profound impact of outdoor time on health, aging, and mental well-being with Dr. John La Puma. Learn practical, science-backed strategies to incorporate outdoor activities into daily life for better sleep, mood, and longevity.Chapters00:00 The Gift of Nature and Outdoor Living03:13 The Science of Outdoor Benefits06:01 Indoor vs Outdoor: The Pollution Debate09:14 The Importance of Morning Light11:57 The Role of Play in Adult Life14:58 The Impact of Screens on Children18:02 The Power of Walking Outdoors26:29 The Importance of Nature and Blue Spaces29:54 Dopamine and the Impact of Screens33:04 Connection to Nature and Mental Health37:18 Tangible Steps to Connect with Nature41:05 The Role of Handwork and Creativity46:11 Nature as Medicine and Houseplants' BenefitsSponsors: LMNTOFFER: Right now, for my listeners LMNT is offering a free sample pack with any LMNT drink mix purchase at DrinkLMNT.com/FEELGOOD. That's 8 single serving packets FREE with any LMNT any LMNT drink mix purchase. This deal is only available through my link so. Also try the new LMNT Sparkling — a bold, 16-ounce can of sparkling electrolyte water.USE LINK: DrinkLMNT.com/FEELGOODDr. John La Puma Resources: Book: Indoor Epidemic: 93% Inside Steals Sleep, Focus & Years—The 7% Outdoor Rx Restores Them.Website: drjohnlapuma.com Bio: John La Puma, MD, ChefMD™ is a two-time New York Times bestselling author, board-certified internist, and professionally trained chef who pioneered Culinary Medicine. He now pioneers EcoMedicine from his small regenerative teaching farm. His new book, Indoor Epidemic, reveals how spending 93% of life indoors steals sleep, focus, and years, and how reclaiming just 7% outdoors can restore them using the evidence-based Outdoor Rx framework. This is clinically validated intervention, presenting nature as foundational medicine, an essential component of health and the missing pillar in optimizing longevity and healthspan.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Show DescriptionDave's upgrading his office with a 3D printer, Chris is ordering 3D printed parts for his van, using mobile Starlink, Chris redesigned his website, playing puzzle games like Statedoku, Chess Peace, and Clues by Sam, how CodePen is going to support pointing domains at your app, and what Vite getting bought by Cloudflare signals. Listen on WebsiteWatch on YouTubeLinks Kagi - Reclaim the Web & Restore Your Privacy A week on the road The New Van – Chris Coyier Chris Coyier – Web craftsman, blogger, author, speaker. Social RSS (?) – Chris Coyier Statedoku — Daily US States Puzzle | Sudoku Meets American Geography Chess Peace - A Peaceful Chess Puzzle Game for iPhone, iPad & Mac Clues By Sam Online Courses • Josh W. Comeau JavaScript for Everyone - Piccalilli SponsorsMacroMacro is a tool to cut through the noise - It's a workspace built for engineers; One place for all your emails, tasks, team chat, and documents. Sign up at Macro.com and get $100 of your subscriptions using code SHOPTALK100

Why do some high-conflict people refuse to settle, even when it hurts them financially and emotionally? In this episode, Rebecca Zung explains the dopamine loop of litigation and reveals how anticipation, conflict, and emotional reactions can keep narcissists and other high-conflict personalities trapped in endless legal battles. Learn the four stages of the cycle and the key strategy for breaking the loop, protecting your peace, and moving toward resolution. #RebeccaZung #Narcissist #HighConflictPersonality #Litigation #ConflictResolution Chapters: 00:00 Why They Keep Moving the Goalposts 00:54 The Real Reason High-Conflict People Won't Settle 02:45 Stage 1: Anticipation and the Dopamine Rush 04:23 Stage 2: The Discharge Phase 06:42 Stage 3: The Trough and Withdrawal 08:10 Stage 4: Re-Engagement and Provocation 09:34 Why Emotional Reactions Fuel the Loop 10:32 How Cases Actually Move Toward Resolution 11:50 Becoming Unavailable as the Reward 12:16 The Neuroscience Behind High-Conflict Behavior 12:37 Final Takeaways and Next Steps

Travelling with ADHD is a whole experience.One minute your brain is screaming, “DOPAMINE! ADVENTURE! NEW SNACKS!” And the next minute you're staring at your suitcase wondering if you need seven pairs of undies for a three-night trip.In this episode, I'm sharing 9 ADHD-friendly travel hacks to help make your next trip easier, calmer & far less chaotic.We'll cover:why you need to check the rules around ADHD medication before you travelhow to reduce the pre-trip panic spiralthe magic of printing, screenshotting & pre-downloading everythingwhy an “empty day before” might be the best gift you give your future selfhow to build your own dopamine & regulation travel kitwhy the Hidden Disabilities Sunflower Lanyard can be so helpful in airportsBecause travelling with ADHD isn't about being perfectly organised.It's about reducing friction, supporting your brain & having a few backup plans for when your brain decides to pack sunscreen but forget socks.Grab the free cheatsheet with all 9 tips here: www.navigatingadultadhd.com/cheatsheetYou can learn more about the Hidden Disabilities Sunflower Lanyard here: https://hdsunflower.comLINKS TO GOOD SH*T FROM NAVIGATING ADULT ADHD:*Join Adulting with ADHD your ADHD toolbox & everything you need to work with your brain*Get our ADHD Coach in your pocket! + the ADHD Goal Setting Workbook (life planner tool)*12 Things I wished my Doctor had told me about Adult ADHD*Find out if you might be living with ADHD - Download Symptoms List*Check out Courses & Coaching with Xena*Learn, Inspire, Share & Connect inside our Facebook Community *Come hang out with me on Instagram!

Welcome to today's ICYMI, where we kick off the week with a quick game-changing tip from past episodes that you might have missed.  Why is catastrophizing and emotional spirals so common in ADHD? We're throwing it back to this helpful advice from ADHD coach Shanna Pearson, on her easy go-to trick to manage mood and strong emotional reactions in the moment. Shanna is the founder of the world's largest one-on-one ADHD coaching company, working with thousands of adults with ADHD every year, and the bestselling author of Invisible ADHD. Follow Shannon and check out her book: https://www.adhdcoaching.com/  https://www.invisibleadhd.com/  Listen to our full episode here. Tune in every Monday for an expert dose of life advice in under 10 minutes. For advertising and sponsorship inquiries, please contact Frequency Podcast Network. Subscribe to my Substack:teachmehowtoadult.substack.comFollow us on the ‘gram:@teachmehowtoadultmedia@gillian.bernerFollow on TikTok: @teachmehowtoadultSubscribe on YouTube

In this episode of The Real Health Podcast, Dr. Barrett explores the growing impact of screen time on children's brain health. We discuss dopamine, attention span, focus, sleep quality, emotional regulation, and why many kids today struggle with boredom, concentration, and healthy development. You'll learn:• How screen time affects dopamine and motivation• Why children need boredom for healthy brain development• The connection between screens and attention issues• How blue light impacts sleep and recovery• Practical ways parents can create healthier screen habits• The six rules we use to build brain-healthy families Whether you're raising toddlers, teens, or simply interested in brain health, this episode will help you navigate technology without sacrificing healthy development.. . . Watch the episode on YouTube here! Click here to view the episode transcript! Podcast Team Dr. Barrett Deubert - Host Grant Crenshaw - Editor (00:00) - Intro: Brain Health (02:26) - Impact of Screens (04:23) - Dopamine (06:19) - Brain Stimulation (09:03) - Sleep Disruption (10:23) - Tips for Families (13:50) - Closing Thoughts DISCLAIMERThis content is strictly the opinion of Dr. Barrett Deubert and is for informational and educational purposes only. It is not intended to provide medical advice or to replace medical advice or treatment from a physician. All viewers of this content are advised to consult their doctors or qualified health professionals regarding health questions and concerns. Neither Dr. Deubert nor the Real Health Co. takes responsibility for possible health consequences of any person or persons reading or following the information in this educational content. All audience members, especially those taking prescription or over-the-counter medications, should consult their physicians before beginning any nutrition, supplement, or lifestyle program.

CarneyShow 06.05.26 Dopamine Kids, Kids Bowl Free, Erin Lapidus, Tom O'Keefe by

What if the most powerful tool to change your life has been right under your nose this whole time — literally?This guest spent his twenties as a high-stress TV producer in New York. On paper, life looked great. Inside, he felt empty and burned out. Getting fired became his turning point. Yoga, meditation, and breathwork pulled him out, and he built a career leading wellness retreats around the world.Now in his 40s, he shares an honest story about change. After a serious back injury forced him to stop teaching yoga, he had to slow down, heal, and rethink everything. He talks about dropping his "masks," saying no to what no longer serves him, and treating your time and energy like a careful investment.His big message is simple: real change starts inside you. Feeling safe in your own body comes first. The breath is the doorway. You don't need apps or gadgets — just a few quiet minutes a day.He also explains why you can't force others to change, and why even difficult people teach us something. The episode ends with a short, calming breathwork practice you can follow along with.Episode Chapters:00:00:00 Introduction00:03:04 Who Is the Guest00:08:29 Reflecting on Change and Evolution00:12:32 The Psychology of Aging00:14:14 Energy as an Investment Strategy00:18:19 Instagram, Dopamine, and Earning Rest00:23:45 Swapping Habits Instead of Quitting00:26:38 Lessons From Retreats: Self-Limiting Beliefs00:28:02 Why Feeling Safe Comes First00:31:06 The Excuse of "No Time"00:36:55 The Guest's North Star00:38:11 Breathwork: The Tool Under Your Nose00:47:49 Simplicity Over Data and Gadgets00:48:55 A Renaissance? Technology, Generations, and Alcohol00:56:26 You Are Responsible for You01:02:32 Why You Can't Force Others to Change01:12:00 The Pebble and the Ripple Effect01:14:02 Finding Gratitude in Hard Lessons01:16:57 Guided Breathwork Practice01:23:03 ClosingMentions & Resources:Michael Henri's Instagram: https://www.instagram.com/michaelyoga.pt/ John Quirk's Instagram: https://www.instagram.com/_johnquirk_/ The IN Movement Instagram: https://www.instagram/com/the_in_movement/James Nestor — Breath (book; guest says he's read it three times)Joe Dispenza (breathwork influence)Wim Hof Method (breathwork influence)Andrew Huberman (podcast mentioned re: dopamine)Michael Singer (author referenced by the guest)Morgan Freeman ("don't let the old man in" quote, raised by the host)Tags: breathwork, meditation, mindfulness, personal growth, self-development, nervous system, healing journey, burnout recovery, back injury, habit change, dopamine, authenticity, retreats, wellness, mental health, presence, somatic practice, stillness, self-awareness, energy management, yoga, inner work, spirituality, life transformation

Fasting trends have officially gone off the rails -  and some of them are actually worth knowing about, while others come with side effects nobody seems to be talking about.So today, we're breaking it all down and cutting through the noise.We're covering:Sardine fasting - the reset trend with a side of gout nobody warned you about  Water fasting -  the most "true" fast, and why it's not for everyone The Fasting Mimicking Diet -  the science-backed method where you actually get to eat  Dopamine fasting -  the trend that has nothing to do with food Why when you fast matters just as much as how long you fastPlus, the electrolyte reminder you probably needed heading into summer. And of course . . . today's feelgood thing.Dr Erin Boynton's Program I'm doing for back pain - click here Big thanks to our sponsor, ITL Health.More information on their magnesium formulations, designed with bioavailability in mind, can be found here:https://itlhealth.ca/

In a world full of constant notifications, distractions, and mental overload, focus has become a skill—not a given. Join Brain Lady Julie as we explore how to strengthen your focus by training your brain, just like you would train a muscle. Learn what's really happening in your brain when your attention drifts, why willpower alone isn't enough, and how small, consistent habits can dramatically improve your ability to concentrate.We'll break down practical, science-backed strategies to sharpen attention, reduce mental clutter, and build deeper focus—whether you're working, studying, or simply trying to be more present in your daily life.For more information on the studies mentioned in today's show…The Shallows… by Nicholes CarrThe Social DilemmaStanford Marshmallow ExperimentConnect with Brain Lady JulieDo you have a great question or topic you'd like Brain Lady Julie to cover? Think you'd be a great guest? Message our producer Kelli@BrainLadySpeaker.com and let us know.PLEASE NOTE: The information contained in this podcast is not at any time and for any reason meant to replace the guidance and/or treatment of any health professional. Whether it be a medical doctor, psychologist, psychotherapist, or anyone in the medical field. If you are under the care of such a health professional, remember this is an “added value” and not designed to replace any care you are currently under.

Many of you may have heard me talk about the impact of brain development on behavior in different life stages (if not, check out my TEDX Talk - link below).  Well, dopamine is in all of us - do you know it is intricately connected with "rewards"?  And CBT is intricately connected to dopamine.Are we seeing a symbiotic relationship?  Check out this episode where we get the dope on dopamine.Be sure to sign up to our email list on the website, and check out the new program structure and pricing options.My TEDX Talk is live!  Beyond Dog Training: The Movement Toward Sentiencehttps://youtu.be/avUugazybwcFind all the episodes on Feedspot, where Dog Training DisrUPted is rated in the top 5 shows in the dog category in Canada:  https://blog.feedspot.com/canadian_dog_podcasts/To become a certified Canine CBT Psychotherapist, and for courses on related topics, please visit the Institute of Canine Psychotherapy. www.instituteofcaninepsychotherapy.comBecome a Certified Canine Behaviorist and Dog TrainerMy Linktree with all my media, presentations, shows, articlesBillie Groom - UPWARD Dogology | Instagram, Facebook | LinktreeHere is the link to the recent article in Psychology Today Mag by Marc Bekoff on Canine CBTDog Training: Perception, Cognition, and Emotions | Psychology TodayBuy My Book! Winner of the 2019 American Best Book Fest Award (pets/narrative/non-fiction)The Art of Urban People With Adopted and Rescued Dogs Methodology: Rescued Dogs: The Misunderstood Breed: Groom, Billie: 9781525547287: Books - Amazon.ca

This week we explore what makes teens want to sit and scroll endlessly or play video games all the time. We discuss how dopamine works and how we can help teens utilize it. Get in in contact with Jeremiah and Selina today for a free coaching consultation! Phone: 208.557.1227 email: info@coreconnection.org Website: Core Connection  Our email: mentalhealthpod21@gmail.com  

Screens aren't just hard for kids to put down because they enjoy them. As Michaeleen Doucleff explains in Dopamine Kids, screens can become powerful "dopamine magnets," pulling children back again and again, often without leaving them feeling calmer, happier, or more fulfilled afterward.In Part 2 of this important conversation on The Child Psych Podcast, Tammy Schamuhn and Michaeleen Doucleff move from understanding the science of dopamine and screen time to exploring practical solutions parents can use at home.Discover evidence-informed strategies to help children reduce screen dependence without constant power struggles. Learn how to create screen-free spaces that support healthy sleep, improved attention, meaningful family connection, and everyday adventure. Michaeleen shares why simply removing screens is rarely enough and how parents can help children reconnect with activities that naturally support emotional well-being.This episode explores how outdoor play, creativity, movement, boredom, relationships, and family rituals can help children find genuine satisfaction beyond digital entertainment.If you're concerned about screen addiction, excessive screen time, video games, social media, YouTube, or the growing impact of technology on children's mental health, this conversation offers practical and hopeful guidance.Because children don't just need less screen time.They need a life that feels richer, more meaningful, and more rewarding than the screen.Michaeleen Doucleff is a science journalist and correspondent for NPR's Science Desk. She holds a PhD in chemistry from the University of California, Berkeley and completed a postdoctoral fellowship at the National Institutes of Health. She is also the New York Times bestselling author of Hunt, Gather, Parent.You can learn more about Michaeleen and her work through Michaeleen Doucleff's official website.Books mentioned in this episode:Dopamine KidsHunt, Gather, ParentAuraYour kid's digital life doesn't come with a playbook.But that doesn't mean you have to stay in the dark.That's where Aura Parents comes in. It combines traditional parental controls—like content filtering, time limits, and Pause the Internet®—with newer digital wellbeing features that show patterns in sleep opportunity, screentime trends, social engagement, and even AI app usage insights.So instead of just limiting screen time, you get more context and insight into changes in patterns and can use that information to decide when to check in with your kid.It's not about control—it's about feeling informed and empowered as you navigate an always changing digital world.Learn more about Aura Parents and start your free trial at auraparents.com/icp Hosted on Acast. See acast.com/privacy for more information.

Your brain is making choices for you before you even realize it. Neuroscientist Emily McDonald, known as M on the Brain, studies how your identity, nervous system, and subconscious programming quietly run the show. Most people think they're choosing. Research shows the neural pattern of a decision lights up in a brain scan before you're consciously aware you've made it. That's the gap Emily spent years learning to close. She grew up with clinical depression, ADHD, anxiety, and a victim mindset baked in by illness and circumstance. She wasn't looking for a life philosophy. She switched her major to neuroscience because it sounded cool and got a 100 on her first exam. What she found changed everything. The science she uncovered is this: your brain holds a model of who you are in the default mode network. It uses that model to predict your thoughts, behaviors, and choices on autopilot. If the model says you're someone who struggles with money, or fails at relationships, or can't focus, your nervous system quietly steers you toward confirming that story. The identity is the destiny. Shifting it means more than positive thinking. It means identity anchors, environment, the people around you, the habits encoded in your body. Emily calls it identity shifting, and she coaches people through it by asking a deceptively simple question: do you have a to-do list or a to-be list? Most people have never sat down to ask who they're becoming, only what they're accomplishing. This conversation will rewire the way you think about why you keep falling back into old patterns, how affirmations can actually work against you, and what neuroscience actually says about the law of attraction. Emily's Website Emily's Instagram Mindcraft Coaching Program In this episode you will: Understand how the default mode network stores your identity and drives your choices below conscious awareness Learn the identity shifting process Emily uses with coaching clients to break subconscious patterns holding them back Discover why affirmations backfire and how to use forward motion and dopamine to make them actually work Explore the neuroscience behind the law of attraction and why you attract what your nervous system is wired for, not what you want Understand how ADHD medication, dopamine dependency, and addiction cycles form in the brain and what it takes to rewire them For more information go to https://lewishowes.com/1935 For more Greatness text PODCAST to +1 (614) 350-3960 Follow The Daily Motivation for essential highlights from The School of Greatness More SOG episodes we think you'll love: Dr Joe Dispenza Dr. K Dr. Sue Morter TOPICS Emily McDonald, neuroscience, identity shifting, default mode network, neuroplasticity, law of attraction, subconscious reprogramming, ADHD, dopamine, limiting beliefs, nervous system alignment, victim mindset Get more from Lewis! Get my New York Times Bestselling book, Make Money Easy!Get The Greatness Mindset audiobook on SpotifyText Lewis AIYouTubeInstagramWebsiteTiktokFacebookX Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

I sit down with Silvi Carter to explore the roots of self-doubt, emotional intensity, and the feeling of never being enough. Together, we unpack how childhood experiences, fatherhood, and the possibility of ADHD have shaped the way he relates to himself and his own energy.We discuss why so many men see their natural vitality as a problem to be solved, and how learning to accept that energy can transform self-worth, emotional regulation, and even addictive patterns. This is a powerful conversation about healing, fatherhood, and learning to work with yourself instead of against yourself.SHOW HIGHLIGHTS00:00 - Introduction01:14 - ADHD, Dopamine, and Emotional Regulation06:58 - Fatherhood Changes Everything09:06 - Learning to White-Knuckle Through Life10:38 - Feeling Like You're Too Much14:18 - The Help He Never Received17:37 - What It Feels Like to Be Truly Understood19:14 - Accepting Support21:21 - Why Does It Feel So Rare?23:01 - What I Needed From My Parents28:07 - The Origins of Self-Doubt and Not Enoughness34:44 - Containment, Energy, and Childhood Development36:26 - Negative Relating to Your Own Nature39:11 - The Volcanic Energy Within42:41 - Acceptance Before Expression44:23 - Creating an Outlet for Your Energy46:10 - Fathering Yourself49:36 - Dopamine, Self-Worth, and Healthy Energy53:05 - Final Reflections and Takeaways***Tired of feeling like you're never enough? Build your self-worth with help from this free guide: https://training.mantalks.com/self-worthPick up my book, Men's Work: A Practical Guide To Face Your Darkness, End Self-Sabotage, And Find Freedom: https://mantalks.com/mens-work-book/Heard about attachment but don't know where to start? Try the FREE Ultimate Guide To AttachmentCheck out some other free resources: How To Quit Porn | Anger Meditation | How To Lead In Your RelationshipBuild brotherhood with a powerful group of like-minded men from around the world. Check out The Alliance. Enjoy the podcast? Leave a review on Apple Podcasts, Stitcher, or Podchaser. It helps us get into the ears of new listeners, expand the ManTalks Community, and help others find the tools and training they're looking for. And don't forget to subscribe on Apple Podcasts | Google Podcasts | SpotifyFor more, visit us at ManTalks.com | Facebook | Instagram

What happens when a University of Chicago-trained psychologist spends three years at Stanford's bipolar disorders clinic, deploys to four war zones with the Navy, works counterterrorism intelligence with the LA Sheriff's Department - and then lands in a Malibu addiction treatment center asking patients one simple question: where does it hurt?Dr. Matthew Schumacher joins me for a wide-ranging conversation about the science of addiction, the biology of balance, and why some of the most powerful tools for recovery are also the oldest ones. From dopamine fasting to behavioral activation to the underrated magic of a social routine, Dr. Schumacher breaks down what actually moves the needle - whether you're in a luxury treatment center in Malibu or sitting at home trying to figure out your next step.Dopamine, balance, and the modern addiction to stimulation — why our brains weren't built for constant input, and what that means for recovery and everyday mental healthThe biology of addiction and tolerance — how the brain stops producing its own feel-good chemicals and why "just stopping" is never the whole answerMood disorders and addiction — the relationship between bipolar disorder, depression, anxiety, PTSD, and substance use, and why treating the underlying condition matters as much as treating the addiction itselfSocial rhythm therapy — how predictable routines around sleep, meals, and social connection stabilize mood, sometimes even without medicationMilitary and law enforcement mental health — the unique trauma, culture, and stigma challenges facing veterans and first responders, including the suicide crisis inside law enforcementThe diagnostic process in addiction treatment — how Dr. Schumacher builds a full picture of a patient using medical records, family history, and collaborative team input before landing on a treatment planPeer connection and the therapeutic community — why lived experience, group therapy, and programs like AA and NA remain some of the most underrated and powerful components of lasting recoveryReasons You Need to Hear This:There's a specific reason your brain craves constant noise — and Dr. Schumacher explains exactly what's happening biologically when you can't turn it off, and what that has to do with why substances feel so necessary in the first place.There's a decades-old treatment for depression that nobody talks about — not a medication, not a complex therapy, not a $300 supplement. Dr. Schumacher reveals what it is, how often you need to do it, and why the fact that nobody profits from it is probably exactly why you've never heard of it.Your daily routine might be doing more damage than you realize — Dr. Schumacher breaks down the surprising biological link between the rhythm of your day and the stability of your mood, and why this might be the most overlooked piece of long-term recovery.The thing your body is actually trying to feel when it reaches for a substance — it turns out nature already built the answer in. Dr. Schumacher explains what it is and how to start accessing it again, especially when you feel like nothing else brings you pleasure anymore.The question he asks every single patient in their first session — it's not what you'd expect from someone with his level of training, and the reason he starts there will genuinely make you rethink what healing actually requires.There's a free, research-backed tool for anxiety that's been around since the 1960s — most people have never tried it because it sounds too simple. Dr. Schumacher makes the case for why simple might be exactly what's needed.If you've been to treatment before and it didn't stick, this episode explains why and it has everything to do with what was - and wasn't - being treated while you were there.

In this episode, Maggie McDaris, CEO and Co-Founder of Phase, breaks down the science and practical application of cycle syncing, explaining how each phase of the menstrual cycle influences energy, cognition, productivity, and overall performance. She walks listeners through the follicular, ovulatory, luteal, and menstrual phases, highlighting the unique strengths and challenges of each stage, including the often-overlooked immune and recovery considerations during the luteal phase. Maggie also explores the role of dopamine, healthy ways to pursue motivation and achievement, and how understanding your biology can help prevent burnout in a culture that often expects women to perform the same way every day. The conversation addresses the stigma surrounding menstrual cycles, the importance of involving men in the discussion, and how cycle awareness impacts sleep, circadian rhythms, and workplace success. Maggie concludes by sharing actionable tips for getting started with cycle syncing and explains how the Phase app helps women align their schedules with their biology to optimize health, productivity, and sustainable performance.Maggie McDaris is the CEO and Co-Founder of Phase and a thought leader at the intersection of human performance and the future of work. A Registered Dietitian, corporate wellness and public health expert, and WELL Accredited Professional, she has spent more than a decade translating health science into practical strategies for real life and work. Before founding Phase, Maggie scaled high-growth wellness businesses and led multidisciplinary teams, gaining a firsthand view of how modern work routinely ignores human biology. That insight became the foundation for Phase, a biology-based productivity system designed to help women connect the dots between their bodies and their workload. Maggie is skilled at turning deep wellness expertise into high-impact, revenue-generating solutions, and she's on a mission to fundamentally reframe how we think about productivity, performance, and sustainable success. She lives in the U.K. with her family.SHOW NOTES:0:39 Welcome to the podcast!4:11 About Maggie McDaris5:30 Welcome her to the show!6:26 Her view on cycle syncing9:27 The phases of the menstrual cycle13:05 Follicular Phase14:46 Ovulatory Phase16:44 Luteal Phase21:10 Dopamine & healthy ways to “chase the high”24:19 How to prevent burnout26:06 Menstrual Phase28:35 Recap of each phase benefits29:25 Evolutionary purpose of ovulation strengths31:42 3 specific phases of Luteal35:08 Immune weakness in luteal phase42:28 How Phase helps optimize your schedule47:15 The stigmatization of menstrual cycles48:32 The role of men in this conversation52:30 Impacting sleep & circadian rhythm57:56 3 Tips on how to get started1:02:44 How to get Phase App1:03:36 Her final piece of advice1:05:39 Thanks for tuning in!RESOURCES:Phase App - Discount code: BIOHACKERBABESLinkedInInstagramTikTokSupport this podcast at — https://redcircle.com/biohacker-babes-podcast/donationsAdvertising Inquiries: https://redcircle.com/brands

Do you forget to eat… until you're suddenly hangry and shaky?Or eat past full & wonder “why did I do that?”If food feels chaotic, confusing, or all-or-nothing - you are not alone.In this episode, we're unpacking how ADHD impacts your relationship with food - from missed hunger cues and hyperfocus, to dopamine-seeking, emotional eating, & food noise.We cover:Why ADHDers forget to eat (and then it becomes urgent)The role of interoception, time blindness & medicationWhy overeating happens (and why it makes sense)Food noise, sensory “icks” & hyperfixation foodsHow executive dysfunction makes eating harder than it “should”ADHD, diet culture & all-or-nothing patternsPlus simple, ADHD-friendly supports to help improve your relationship with food & eatingIf you've ever felt like you're “bad with food”… This episode will help.LINKS TO OTHER GOOD SH*T:*Join Adulting with ADHD your ADHD toolbox & everything you need to work with your brain*Get our ADHD Coach in your pocket! + the ADHD Goal Setting Workbook (life planner tool)*12 Things I wished my Doctor had told me about Adult ADHD*Find out if you might be living with ADHD - Download Symptoms List*Check out Courses & Coaching with Xena*Learn, Inspire, Share & Connect inside our Facebook Community *Come hang out with me on Instagram!

Başak Erten is a creative strategist, radio and brand consultant, and founder of The Art of Audacity — a cultural platform for women in creative industries, as featured in Forbes. She's spent over eight years producing content across the BBC, Sony Music Entertainment, and branded work for Vanity Fair, Bloomberg, and Nike.In this episode she brings three sharp takes on where culture, media, and consumer behaviour are heading — and why the old rules no longer apply.She argues that audiences have moved past passive consumption and are demanding participation; that the era of aspirational, polished living is collapsing under its own weight; and that the third space — not the boardroom, not the bar — is now where the most meaningful professional and personal relationships are being built.Honest, direct, and occasionally incendiary.Welcome to The Marvyn Harrison Podcast — a story-driven conversation exploring identity, fatherhood, masculinity, relationships, culture, politics, sport, and modern life.In each episode, Marvyn Harrison sits down with leading thinkers, creatives, athletes, policymakers, and cultural voices to unpack the defining moments that shaped them. Through image prompts, structured storytelling, and revealing game segments, guests explore pivotal memories, career turning points, personal struggles, and the beliefs that guide their decisions today.Expect honest discussions on mental health, family dynamics, leadership, equity, ambition, resilience, and the realities of navigating success in Britain and beyond.This is a podcast about clarity, where lived experience meets sharp cultural insight. Hosted on Acast. See acast.com/privacy for more information.

People love to talk about dopamine like it's the enemy.   Dopamine addiction. Dopamine detox. Cheap dopamine. Instant gratification. Chasing the high.   And while there is truth to all of that, I think we sometimes miss the bigger picture.   Dopamine is not automatically bad. It is your body's natural reward system. The real issue is not that we like feeling good — it's what behaviours we are rewarding.   In this episode, I talk about a realization I had while running in the sun with my dad's dog, listening to music, and feeling completely stoked on life. That was a dopamine rush too — but it was attached to something good.   This episode is about learning how to stop demonizing dopamine and start using it to build better habits, stronger discipline, better mental health, and a life you actually want to keep moving toward.   If you liked the show, help it grow!   Leave a review and rate 5 stars on Apple Podcast, and Spotify!

10€ offert sur votre 1ère commande Féroce avec le code BIOMECANIQUE10 : ⁠⁠https://feroce.food/⁠Le Dr Boris Dufournet est neurologue, spécialisé en neurologie intégrative, médecine métabolique et neurométabolique, avec une approche holistique centrée sur la prévention, la santé globale et la performance durable.⁠⁠Site et formations⁠⁠⁠Youtube⁠Bibliographie :⁠Les intelligences multiples (Howard GARDNER)Le génie des Dys – Être Dys et Haut Potentiel à la fois (Michel HABIB)La constellation des Dys : Bases neurologiques de l'apprentissage et de ses troubles (Michel HABIB)⁠⁠Obesity Before Birth: Maternal and prenatal influences on the offspring (Robert LUSTIG)Living Paleo Style: Overcome The Ancestral-Modern Mismatch to Regain Your Natural Wellbeing (Miki BEN-DOR)Ketones The Fourth Fuel (Travis CHRISTOFFERSON)Résistance à l'insuline (Benjamin BIKMAN)Ketogenic: The Science of Therapeutic Carbohydrate Restriction in Human Health (Tim NOAKES et associés)Nourrir son cerveau, soigner son mental (Georgia EDE)CHAPITRES :0:00 Introduction2:32 Parkinson, la plus fréquente après Alzheimer6:06 Les cooccurrences et le diagnostic12:31 Nouvelles classifications, mêmes maladies17:59 Les mécanismes de propagation21:48 Les signes précoces de Parkinson32:27 Le sommeil paradoxal révélateur38:35 Dopamine et monde moderne43:06 Chocs et risques neurologiques50:00 Le multitasking est-il dangereux ?58:28 Muscler l'attention1:03:13 Construire une réserve cognitive anti-Alzheimer1:06:59 Wi-Fi, Bluetooth, AirPods : faut-il s'inquiéter ?1:10:03 Électrosensibilité : réalité ou effet placebo ?1:16:32 Ce que les études sur les ondes montrent réellement1:18:26 Les vrais facteurs de risque du déclin cognitif1:23:19 HPI, TDAH, Asperger : ce que l'on comprend mal1:30:15 Une nouvelle façon de comprendre les profils cognitifs1:33:49 Les travaux de Michel Habib1:37:50 Distinction entre autisme et syndrome d'Asperger1:40:31 Exemples de profils1:43:36 Modèle dimensionnel1:49:03 Asperger et abstraction1:52:26 Le haut potentiel émotionnel1:54:53 Hypersensibilité ou burn-out2:02:52 Comprendre le TDAH2:11:35 Dopamine et vitesse2:17:02 Parkinson et Alzheimer2:19:28 Métabolisme et cétose2:22:12 Prévention personnaliséeBIOMÉCANIQUE :​⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Instagram⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠​⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Youtube⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠​⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Spotify⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠​⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Apple Podcasts⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠​⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Discord⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠​⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Website⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠​⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠La Lettre Biomécanique⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠™⁠⁠ Hébergé par Acast. Visitez acast.com/privacy pour plus d'informations.

Season 15, Episode 397 revisits research and real-world practice showing movement is more than fitness: it activates the brain, boosts attention, enhances learning, and sustains motivation. Dr. Chuck Hillman's studies reveal how even short bouts of exercise light up brain activity, while Paul Zientarski's Naperville program demonstrates how heart-rate monitoring and purposeful movement improve readiness, recovery, and academic performance. In EP 397: Movement, Motivation, and Brain Activation with Dr. Chuck Hillman and Paul Zientarski, we explore why movement may be one of the most powerful tools we have for improving brain function, learning, motivation, and performance. In this episode, we cover: ✅ Why most children are not meeting the recommended daily physical activity guidelines and what we can do to change that. ✅ How exposing children to a variety of activities helps them discover movement they enjoy—and are more likely to continue throughout their lives. ✅ Why there is no perfect exercise program, and why the best exercise is the one you'll consistently do. ✅ How enjoyment, reward, and dopamine reinforce healthy habits and keep the Motivation Loop repeating. ✅ What Naperville Central High School learned from heart rate monitoring and how recovery impacts performance. ✅ Why peak performance requires both effort and recovery. ✅ How exercise changes the brain, improving attention, learning, memory, and cognitive performance. ✅ The groundbreaking research behind Spark: The Revolutionary New Science of Exercise and the Brain and how it changed the way educators think about learning. ✅ Why movement is not a break from learning—but one of the most effective ways to prepare the brain for learning. ✅ How movement fits into our Phase 2 Motivation Loop, helping transform motivation into action and sustaining long-term performance. The biggest takeaway? Movement isn't just exercise. It's activation. It's preparation. It's performance. When we move our bodies, we activate the brain systems responsible for attention, learning, motivation, and success. The episode highlights practical takeaways: expose children to varied enjoyable activities, prioritize consistency over intensity, use movement as cognitive preparation, and track recovery to protect motivation. Movement becomes a bridge between motivation and sustained performance—improving focus today and long-term brain health tomorrow. Welcome back to Season 15 of the Neuroscience Meets Social and Emotional Learning Podcast. I'm Andrea Samadi, and on this podcast, we bridge the science behind social and emotional learning, emotional intelligence, and practical neuroscience so we can create measurable improvements in well-being, achievement, productivity, and results. Movement, Motivation, and Brain Activation with Dr. Chuck Hillman and Paul Zientarski This week, we continue our journey through Phase 2: Neurochemistry and Motivation, where we've been exploring one central question: What drives sustained effort and forward movement? So far, we've learned that motivation begins with belief and meaning from Bob Proctor[i], is shaped by our thought patterns with Dr. Caroline Leaf,[ii] strengthened through attention and reward with Dr. John Medina[iii], and powered by the brain's dopamine-based motivation system through Dr. Anna Lembke's[iv] work. But today, we arrive at a fascinating question: What happens when we actually move? Because motivation isn't just something that happens in the mind. The brain was designed to work in partnership with the body. And according to our review of today's two guests, one of the most powerful ways to activate attention, learning, memory, and motivation is through movement itself. This week we're revisiting insights from two pioneers whose work helped transform our understanding of movement and learning. First, Dr. Chuck Hillman, one of the world's leading researchers on exercise and brain function, whose groundbreaking research has shown how physical activity improves attention, executive function, learning, memory, and academic performance from EP 123[v] back in April 2021. Next, we will review Paul Zientarski, the former Physical Education Coordinator and football coach at Naperville Central High School, (In Illinois) whose work with the school's innovative Zero Hour PE Program helped put Naperville on the map for extraordinary academic achievement. Alongside his colleagues at Naperville, Paul demonstrated that exercise wasn't simply improving fitness—it was preparing students' brains to learn. Together, Dr. Hillman provides the science, while Paul Zientarski helps to demonstrate what that science looks like in the real world. Their combined work shows us that movement is far more than a physical activity. It is a powerful tool for activating the brain, enhancing learning, improving focus, and supporting the motivation needed for sustained performance. In other words, movement is the bridge between motivation and sustaining our performance. Let's dive in with Dr. Chuck Hillman and discover the science behind The Power of Movement and Brain Activation. CLIP 1: Getting Kids Moving for Life Summary In this clip, Dr. Chuck Hillman highlights a growing concern: the vast majority of children are not meeting the recommended physical activity guidelines. Current recommendations suggest that children should engage in at least 60 minutes of moderate-to-vigorous physical activity each day, including aerobic exercise and activities that strengthen bones and muscles. Dr. Hillman explains that the challenge isn't simply knowing the guidelines—it's finding ways to engage children in movement when many adults aren't meeting the recommendations themselves. This is why childhood is such an important time to expose young people to a wide variety of physical activities, helping them discover forms of movement they enjoy and can continue throughout their lives. Key Takeaways ✔ Most children are not getting enough physical activity. Many young people fall short of the recommended 60 minutes of daily movement needed for optimal physical and cognitive development. ✔ Movement supports both brain and body health. Exercise is not just about fitness—it supports attention, learning, memory, emotional regulation, and overall well-being. ✔ Children need exposure to different activities. Not every child will enjoy the same sport or activity. The goal is to help them discover movement they genuinely enjoy. ✔ Parents and adults model behavior. Children are more likely to be active when the adults around them value and participate in physical activity. ✔ Early habits can last a lifetime. The activities children enjoy today often become the healthy habits they carry into adulthood. Tips to Implement Expose Children to Variety

Send us Fan MailWhat if everything you've been told about change, motivation, and stress is missing the most important piece — your brain?This week I'm joined by Lisa Riegel, educator by training, strategist by practice, and someone who has dedicated her career to translating brain science into language and tools that actually help people feel more self-aware, regulated, and in control. Lisa is the creator of the NeuroWell Framework and the Aspirations to Operations Commitment Framework, and whether she's working with Fortune 500 leaders, school systems, or individuals navigating their own lives, her message is the same: real change starts in the brain.In this conversation we cover so much ground, and I think you're going to find it as accessible and practical as I did. We talk about:Why 80% of the thinking happening in your brain right now is unconscious — and what that means for your behavior, your reactions, and your relationshipsMeet Bob and Harold — Lisa's brilliant, accessible way of explaining how your amygdala and thalamus work together to filter reality and trigger your stress responseThe four states of wakefulness (calm, alert, alarm, fear) and exactly what happens neurologically when you burn outWhy change is so hard — and why most change initiatives, in organizations and in our personal lives, fail before they even beginThe difference between outcome goals and action goals, and why that distinction is everythingWhy we don't know what our body feels like when we're happy — and a simple morning practice to start changing thatThe power of identifying not just what stresses you out, but why — and how uncovering the underlying fear gives you genuine self-controlWhy celebration is the most underused and misunderstood tool in leadership, parenting, and self-developmentHow to create your own resilient inner bubble in a world that feels increasingly out of controlLisa brings so much warmth and wisdom to this conversation, and her ability to take complex brain science and make it feel immediately usable is truly a gift. This one is for the leaders, the parents, the burnout survivors, and anyone who has ever wondered why they keep reacting in ways they don't intend to.Resources:Free Masterclass:  The Alchemy of the Perimenopause PortalAyurvedic Dosha Quick Reference GuideAbhyanga Self Massage GuideWeekend Nervous System ResetNourished For Resilience Workbook Find me at www.nourishednervoussystem.comand @nourishednervoussytem on Instagram

Most diets fail because they never address what the food was doing for you emotionally. In this episode, Dr. Brendan McCarthy explains the stress-craving loop behind emotional eating, why ultra-processed foods feel impossible to resist, and how shame actually reinforces the cycle. You'll learn: • Why cravings feel automatic • How stress drives food urges • The “cue → urge → reward” loop • A simple 9-minute method to interrupt cravings This isn't about perfection or willpower. It's about understanding the pattern so you can finally begin to change it.   Citations:  Boswell, Rebecca G., and Hedy Kober. “Food Cue Reactivity and Craving Predict Eating and Weight Gain: A Meta-Analytic Review.” Obesity Reviews, vol. 17, no. 2, 2016, pp. 159–177. doi:10.1111/obr.12354. Use for: Food cues can trigger craving and eating even without true hunger. Berridge, Kent C., and Terry E. Robinson. “Liking, Wanting, and the Incentive-Sensitization Theory of Addiction.” American Psychologist, vol. 71, no. 8, 2016, pp. 670–679. doi:10.1037/amp0000059. Use for: “Wanting” food is not the same as true pleasure. Schultz, Wolfram, Peter Dayan, and P. Read Montague. “A Neural Substrate of Prediction and Reward.” Science, vol. 275, no. 5306, 1997, pp. 1593–1599. doi:10.1126/science.275.5306.1593. Use for: Dopamine helps encode reward prediction and learning. Wood, Wendy, and Dennis Rünger. “Psychology of Habit.” Annual Review of Psychology, vol. 67, 2016, pp. 289–314. doi:10.1146/annurev-psych-122414-033417. Use for: Habits form through repeated cue-context loops. Laborde, Sylvain, et al. “Effects of Voluntary Slow Breathing on Heart Rate and Heart Rate Variability: A Systematic Review and a Meta-Analysis.” Neuroscience & Biobehavioral Reviews, vol. 138, 2022, article 104711. doi:10.1016/j.neubiorev.2022.104711. Use for: Slow breathing supports parasympathetic regulation and stress reduction. Lieberman, Matthew D., et al. “Putting Feelings into Words: Affect Labeling Disrupts Amygdala Activity in Response to Affective Stimuli.” Psychological Science, vol. 18, no. 5, 2007, pp. 421–428. doi:10.1111/j.1467-9280.2007.01916.x. Use for: Naming emotions can reduce emotional reactivity. Gollwitzer, Peter M. “Implementation Intentions: Strong Effects of Simple Plans.” American Psychologist, vol. 54, no. 7, 1999, pp. 493–503. doi:10.1037/0003-066X.54.7.493. Use for: “If-then” plans improve behavior change under stress. Forman, Evan M., et al. “A Comparison of Acceptance- and Control-Based Strategies for Coping with Food Cravings: An Analog Study.” Behaviour Research and Therapy, vol. 45, no. 10, 2007, pp. 2372–2386. doi:10.1016/j.brat.2007.04.004. Use for: Acceptance and urge-surfing strategies help cravings pass without acting on them. Hall, Kevin D., et al. “Ultra-Processed Diets Cause Excess Calorie Intake and Weight Gain: An Inpatient Randomized Controlled Trial of Ad Libitum Food Intake.” Cell Metabolism, vol. 30, no. 1, 2019, pp. 67–77.e3. doi:10.1016/j.cmet.2019.05.008. Use for: Ultra-processed foods increase intake and reinforce overeating patterns.   Dr. Brendan McCarthy is the founder and Chief Medical Officer of Protea Medical Center in Arizona. With over two decades of experience, he's helped thousands of patients navigate hormonal imbalances using bioidentical HRT, nutrition, and root-cause medicine. He's also taught and mentored other physicians on integrative approaches to hormone therapy, weight loss, fertility, and more. If you're ready to take your health seriously, this podcast is a great place to start.

College football, modern day media, and untold stories… On the net, it's a positive. ------ Tour Dates: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://johncristcomedy.com/tour/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ New Merch: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://store.johncristcomedy.com/ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ----- SUPPORT OUR SPONSORS PONCHO: Go to https://ponchooutdoors.com/netpositive for $10 off and free shipping on your first order. MANDO: Control Body Odor ANYWHERE with @shop.mando and get $5 off your Starter Pack (that's over 40% off) with promo code NETPOSITIVE at https://shopmando.com RIDGE: Upgrade your wallet today! Get 10% OFF @Ridge with code NETPOSITIVE at https://www.Ridge.com/NETPOSITIVE COVE: Go to ⁠https://covesmart.com⁠, and use code NETPOSITIVE for an additional 70% OFF your first order —easy,  affordable, and peace of mind guaranteed. ----- SUBMIT A VIDEO: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://bit.ly/NetPositiveMail⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ----- EMAIL US: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠netpositive@johncristcomedy.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ----- WRITE US: Net Positive P.O. Box 40268 Nashville, TN 37204 ----- Subscribe to the show on your favorite podcast platform, and follow us on social media for clips, bonus content, and updates throughout the week. ----- NET POSITIVE PODCAST ON SOCIAL: Instagram: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.instagram.com/netpositivepodcast⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ TikTok: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.tiktok.com/@netpositivepodcast⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ YouTube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.youtube.com/@netpositivepod⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ----- JOHN CRIST ON SOCIAL: YouTube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.youtube.com/user/johnbcrist⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ TikTok: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.tiktok.com/@johncristcomedian⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Facebook: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.facebook.com/johnbcrist/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Instagram: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.instagram.com/johnbcrist/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ X: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://x.com/johnbcrist⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Website: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://johncristcomedy.com/ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ----- PRODUCED BY: Alex Lagos: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.instagram.com/mralexlagos⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Easton Smith: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.instagram.com/eastonjsmith⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Lagos Creative: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.lagoscreative.co⁠⁠ Learn more about your ad choices. Visit megaphone.fm/adchoices

In this episode of The Jimmy Rex Show, Jimmy sits down with Dustin Pederson, founder of Unorthodox Training, professional bodybuilder, and the coach who helped him go from 22% body fat to 9% for his first bodybuilding competition.This conversation goes way beyond workouts and macros.They break down what actually causes most people to fail in fitness, why emotional health drives physical health, how dopamine addiction sabotages progress, sustainable fat loss strategies, traveling without destroying your diet, and the mindset shifts required to create lasting transformation.If you've struggled to get in shape, stay disciplined, or maintain results long term, this episode gives you the real blueprint.Follow Dustin Pederson: IG

In Part 1 of this powerful conversation, Tammy Schamuhn sits down with Michaeleen Doucleff, author of Dopamine Kids, to explore what is really happening in children's brains when they beg for more screen time, melt down when devices are taken away, or seem unable to pull themselves away from video games, social media, YouTube, or ultra-processed foods.Many parents have been taught that dopamine is simply the brain's “pleasure chemical.” But Doucleff explains that dopamine is more accurately understood as part of the brain's motivation and seeking system — the internal drive that says: keep going, get more, don't stop yet.This shift in understanding changes everything.When children become explosive after screen time ends, their brains may not be responding to joy or satisfaction. Instead, they may be caught in a cycle of constant wanting. Screens and ultra-processed foods can act as powerful “dopamine magnets,” pulling children toward repeated stimulation while leaving them feeling more dysregulated, disconnected, and emotionally depleted.In this episode, Tammy and Michaeleen unpack:why screen time battles can feel so intense for familieshow dopamine-driven behaviors affect motivation, focus, sleep, and emotional regulationwhy children are especially vulnerable to highly stimulating technology and foodshow modern childhood has become shaped by endless craving and overstimulationwhy this is not about blaming parents or shaming childrenhow understanding the brain can help parents respond with more compassion, clarity, and confidenceThis conversation is essential listening for parents, educators, and caregivers trying to understand why screen limits feel so difficult, why transitions off devices can trigger meltdowns, and why many children today seem trapped in cycles of “more, more, more.”In Part 2, releasing June 3, Michaeleen shares practical, science-backed strategies to help families reduce screen dependence, shift unhealthy habits, and reconnect children with play, sleep, focus, creativity, and real-life joy.Michaeleen Doucleff is a science journalist and correspondent for NPR's Science Desk. She holds a PhD in chemistry from the University of California, Berkeley and completed a postdoctoral fellowship at the National Institutes of Health. She is also the New York Times bestselling author of Hunt, Gather, Parent.You can learn more about Michaeleen and her work through Michaeleen Doucleff's official website.Books mentioned in this episode:Dopamine KidsHunt, Gather, ParentAuraYour kid's digital life doesn't come with a playbook.But that doesn't mean you have to stay in the dark.That's where Aura Parents comes in. It combines traditional parental controls—like content filtering, time limits, and Pause the Internet®—with newer digital wellbeing features that show patterns in sleep opportunity, screentime trends, social engagement, and even AI app usage insights.So instead of just limiting screen time, you get more context and insight into changes in patterns and can use that information to decide when to check in with your kid.It's not about control—it's about feeling informed and empowered as you navigate an always changing digital world.Learn more about Aura Parents and start your free trial at auraparents.com/icp Hosted on Acast. See acast.com/privacy for more information.

If Part 1 was about the field of sexual medicine, Part 2 is about the marriage at the center of it. Dr. Jenni Skyler and Daniel Lebowitz return to their conversation with Dr. Irwin and Sue Goldstein, and this time, the questions get more personal. How do you stay married for fifty years? What does great sex actually look like across the decades? And what happens when a woman who has spent her career in sexual medicine starts experiencing low desire herself? Sue Goldstein opens up about her own journey through peri-menopause and the slow erosion of her libido- what she calls "duty sex", and the medications that brought not just her sex drive back, but a playfulness in her marriage she hadn't realized had gone missing. She walks listeners through her menopause toolbox of five treatments, explains why she's "76 and feels like she's in her 50s", and dismantles the lingering fears from the Women's Health Initiative that have kept generations of women in what she calls hormone prison. Dr. Irwin shares his own daily protocols for sexual health, why he believes most older men are leaving capacity on the table, and the surprising data from their own clinic- that more than half the Vyleesi prescriptions they write are off-label for men. They explore why dopamine is dopamine, regardless of gender. The reality of persistent genital arousal disorder. And a remarkable story of a teenage horseback rider whose chronic arousal turned out to be a herniated disc. This episode is full of practical wisdom, clinical innovation, and one of the most real conversations about long-term love you'll hear all year. The Goldsteins' secret to fifty years of marriage? Best friends, good sex, and the willingness to keep trying new things — including a chocolate sauce on the day before you change the sheets. Irwin Goldstein, MD, IF (he/him/his). Director, San Diego Sexual Medicine 5555 Reservoir Drive, Suite 300, San Diego, CA 92120, Director, Sexual Medicine, UC San Diego Health East Campus, San Diego, CA. Clinical Professor of Urology, University of California at San Diego. Voluntary Clinical Professor of Obstetrics, Gynecology and Reproductive Services Past President, International Society for the Study of Women’s Sexual Health. Past President, Sexual Medicine Society of North America. Editor Emeritus, Sexual Medicine Reviews, The Journal of Sexual Medicine, International Journal of Impotence Research. Phone: 619 265-8865 - Mobile: 619 987-7432. Email: dr.irwingoldstein@gmail.com. http://www.sandiegosexualmedicine.com. Like us on Facebook: https://www.facebook.com/SDSexMed. X: http://twitter.com/SDSexualMedSee omnystudio.com/listener for privacy information.

Have you ever been consumed by someone you knew wasn't healthy for you? Replayed conversations on loop? Lived for a text back? Felt more alive with someone unavailable than with someone who was fully present?You are not weak. You are not crazy. You are caught in what Brianne Davis-Gantt calls The Fantasy Loop™ — a 7-stage nervous system cycle that keeps people addicted to unavailable love, unavailable people, and unavailable versions of themselves.In this pivotal episode of Secret Life Podcast, Brianne introduces The Fantasy Loop™ for the first time — the trademarked teaching framework she has spent years developing through her own recovery and her work with hundreds of clients. This is not about judging yourself. This is about finally understanding the cycle so you can break it.THE 7 STAGES OF THE FANTASY LOOP™:Stage 1 — Emotional EmptinessThe loop doesn't begin with a person. It begins with an inner void — loneliness, attachment wounds, unmet emotional needs, nervous system dysregulation. That emptiness becomes the doorway.Stage 2 — ActivationAn unavailable, inconsistent, or emotionally distant person appears and your nervous system lights up. What you think is chemistry is actually nervous system activation. This is where people confuse activation for love.Stage 3 — Fantasy ProjectionYour mind fills in the gaps. You stop seeing the real person. You project qualities onto them that don't exist and build an entire future based on potential, not reality. The brain becomes attached to the possibility instead of the person. The fantasy only thrives in uncertainty.Stage 4 — On and Off ReinforcementThe addiction deepens through intermittent reinforcement — just enough connection to keep you hooked, followed by withdrawal. Dopamine isn't driven by stability. It's driven by anticipation. This is why toxic attachments feel chemically addictive.Stage 5 — Obsession and Self-AbandonmentThe overthinking begins. Replaying conversations. Checking your phone. Losing your boundaries. Your world shrinks around the fantasy. The Fantasy Loop is not just about chasing someone. It's about abandoning yourself in the process.Stage 6 — Collapse and WithdrawalReality returns. They pull away, ghost, or the fantasy finally cracks. What follows isn't just heartbreak — it's withdrawal. Toxic attachment activates the same reward system as a chemical addiction. This is why people go back when they know it's hurting them.Stage 7 — ReattachmentInstead of healing the wound underneath, the brain searches for another high, another unavailable person, another fantasy. Different face. Same nervous system pattern. And the loop starts again.HOW TO BREAK THE FANTASY LOOP™:1. Awareness — you cannot heal a pattern you cannot see2. Regulate your nervous system — this is body-based attachment conditioning3. Heal the attachment wound underneath — anxious, avoidant, or dismissive4. Rebuild self-worth and boundaries from the inside out5. Choose reality over fantasy — and learn what real love actually feels likeYou are not broken. This is not a character flaw. This is a survival pattern. And survival patterns can be healed.Brianne Davis-Gantt is living proof.Resources at secretlifepodcast.comShare your secret: secretlifepodcast@icloud.com