Podcasts about drugs

We hear from a Mexican city in Sinaloa state where one of the big drug cartels is locked in its own civil war. Our correspondent Quentin Sommerville visited the state capital, Culiacán, where he witnessed scenes of brutal violence that have brought pain and terror to residents. Also: Cuba says its coastguard has killed four people on board a US-registered speedboat, in an exchange of fire off the Cuban coast. It said those on the boat were Cubans, living in the US, with a history of violent activity - and "terrorist" intentions. The American Secretary of State, Marco Rubio, called the shootout "highly unusual" and said the US would conduct its own investigation into the incident and not rely on the Cuban version of events. A British clinical trial on more than 500 people across 15 countries found that a new tablet to treat HIV - which combines two current treatments - is highly effective at keeping the virus suppressed. A BBC Eye investigation has revealed that Nepal's top police officer gave the order allowing the use of live fire during last year's deadly crackdown on Gen Z protests - one of the worst in the country's history. And the robot that conducted Denmark's National Symphony Orchestra. We have the verdict on its performance. The Global News Podcast brings you the breaking news you need to hear, as it happens. Listen for the latest headlines and current affairs from around the world. Politics, economics, climate, business, technology, health – we cover it all with expert analysis and insight. Get the news that matters, delivered twice a day on weekdays and daily at weekends, plus special bonus episodes reacting to urgent breaking stories. Follow or subscribe now and never miss a moment. Get in touch: globalpodcast@bbc.co.uk

We hear from a Mexican city in Sinaloa state where one of the big drug cartels is locked in its own civil war. Our correspondent Quentin Sommerville visited the state capital, Culiacán, where he witnessed scenes of brutal violence that have brought pain and terror to residents. Also: Cuba says its coastguard has killed four people on board a US-registered speedboat, in an exchange of fire off the Cuban coast. It said those on the boat were Cubans, living in the US, with a history of violent activity - and "terrorist" intentions. The American Secretary of State, Marco Rubio, called the shootout "highly unusual" and said the US would conduct its own investigation into the incident and not rely on the Cuban version of events. A British clinical trial on more than 500 people across 15 countries found that a new tablet to treat HIV - which combines two current treatments - is highly effective at keeping the virus suppressed. A BBC Eye investigation has revealed that Nepal's top police officer gave the order allowing the use of live fire during last year's deadly crackdown on Gen Z protests - one of the worst in the country's history. And the robot that conducted Denmark's National Symphony Orchestra. We have the verdict on its performance. The Global News Podcast brings you the breaking news you need to hear, as it happens. Listen for the latest headlines and current affairs from around the world. Politics, economics, climate, business, technology, health – we cover it all with expert analysis and insight. Get the news that matters, delivered twice a day on weekdays and daily at weekends, plus special bonus episodes reacting to urgent breaking stories. Follow or subscribe now and never miss a moment. Get in touch: globalpodcast@bbc.co.uk

We're joined by Bad Religion co-founder and Epitaph Records founder Brett Gurewitz at Brain Dead Studios in Hollywood, CA. We discuss growing up in the West San Fernando Valley, discovering the Ramones in the late 70s, meeting Greg Graffin and Jay Bentley at El Camino Real High School and starting Bad Religion in the quad, founding Epitaph to put out the Bad Religion 7", the entire BR discography, leaving the band right before the overnight success of Offspring's Smash, rejoining for Process of Belief, his thoughts on streaming as it dominates the music landscape today, and his favorite hardcore records ever. A genuine honor with a genuine legend and one of the best punk songwriters to ever live. Check out Colin's hand picked Bad Religion playlist of hits and deep cuts and enjoy: Spotify & Apple Music. _______________ Cool links: • Get 15% off DUNABLE GUITARS with code HARDLORE: https://dunableguitars.com • Get 15% off TIMELESS COFEE site-wide, including coffee subscriptions, cookies and cakes with code HARDLORE. _______________ 00:00:00 - Start 00:00:48 - Brett Gurewitz, Epitaph Records in 2025/2026 00:02:26 - Growing Up in the San Fernando Valley, Finding Music, CCR 00:06:44 - From Elton John to the Ramones: Discovering Punk 00:08:40 - Meeting Greg Graffin & Jay Bentley, Starting Bad Religion 00:16:29 - When Does It Become "Bad Religion"? 00:19:40 - What is Punk, and What is Hardcore? 00:23:28 - The "Crossbuster" & The Bad Religion Logo (Fritz Quadrata Pro Bold) 00:27:32 - Starting Epitaph Records For the BAD RELIGION S/T 7" 00:36:41 - HOW COULD HELL BE ANY WORSE? 00:50:02 - INTO THE UNKNOWN... Selling 10,000 Records (and getting them all back) 00:53:13 - Going to Rehab/Leaving Bad Religion 00:55:17 - Pardon This Interruption... 00:58:32 - Epitaph During 1983-1987, Rejoining Bad Religion, West Beach Studios 01:04:54 - The Beach Boys to the The Adolescents to Bad Religion 01:06:56 - SUFFER... Operation Ivy, NOFX, Growth in Epitaph & As an Engineer 01:10:47 - NO CONTROL... Learning from Suffer, Doing Everything with Integrity, Tribute to the Germs 01:17:05 - Greg Songs That Gave Him Goosebumps, No Control Title Track 01:20:35 - Tony Hawk's Pro Skater, I Want Something More, Tape Editing in Recording 01:24:40 - AGAINST THE GRAIN... Being Insecure With 21st Century Digital Boy, Songwriting, Picking Singles 01:30:45 - Touring For Bad Religion By 1990 01:32:40 - GENERATOR... Never Writing on Drugs, Split 7" With Noam Chomsky, Bobby Schayer 01:36:20 - RECIPE FOR HATE... American Jesus, Eddie Vedder, Touring While Balancing Epitaph, Struck A MF Nerve 01:41:39 - Bad Religion Leaving Epitaph & Signing to Atlantic 01:45:31 - STRANGER THAN FICTION... Andy Wallace, Better Off Dead, Falling Off the Wagon 01:49:49 - Leaving Bad Religion, Offspring's Smash, Rancid's ... And Out Come The Wolves, Feel The Darkness Re-Release 01:57:44 - Brian Baker, Losing Contact with The Band 01:59:24 - The Landscape of Music Changing, Napster, Torrents, &  Brett's Thoughts on Spotify 02:12:39 - PROCESS OF BELIEF... Returning to Bad Religion, Brooks Wackerman, Sorrow 02:20:15 - EMPIRE STRIKES FIRST... L.A. Is Burning, The Iraq War, Why Brett Doesn't Play With BR Now 02:24:38 - NEW MAPS OF HELL, THE DISSENT OF MAN, TRUE NORTH, AGE OF UNREASON... 02:31:28 - Brett's Top 4 Hardcore Records HardLore: A Knotfest Series, Fueled by Monster EnergyEdited by Steven Grise • Title sequence by Nicholas MarzlufJoin the HARDLORE PATREON to watch every single weekly episode early and ad-free, alongside exclusive monthly episodes.Join the HARDLORE DISCORD for community discussions and to participate in our future Q&A episodes.FOLLOW HARDLORE: INSTAGRAM, TWITTER, SPOTIFY, APPLEFOLLOW COLIN: INSTAGRAMFOLLOW BO: INSTAGRAM, TWITTER For sponsorship opportunities, email us! hardlore@knotfest.com Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Cindy Eckert (Addyi) joins JVN to talk all things women's sexual health, libido, and the science behind desire. Cindy breaks down her TIME100 Health feature, gives a preview of her upcoming Paramount+ documentary The Pink Pill: Sex, Drugs & Who Has Control, shares the iconic story of Addyi (often called the “female Viagra”) and her fight for better access to women's health care. Jonathan and Cindy also unpack the science of libido, how hormones, stress, and stigma affect sexual wellness, and why sexual health is directly connected to quality of life.  If you've ever wondered about low libido, women's sexual desire, Addyi, or how to talk about sexual health without shame - this episode is for you! Full Getting Better Video Episodes now available on YouTube.  Follow Cindy Eckert on @cindypinkceo  Follow us on Instagram @gettingbetterwithjvn Jonathan on Instagram @jvn Executive Producer, Chris McClure Producer, Editor & Engineer is Nathanael McClure Production support from Chad Hall Our theme music is also composed by Nathanael McClure. Check out the JVN Patreon for exclusive BTS content, extra interviews, and much much more - check it out here: www.patreon.com/jvn  Curious about bringing your brand to life on the show? Email podcastadsales@sonymusic.com. Learn more about your ad choices. Visit podcastchoices.com/adchoices

 “Thug Drugs: Policy” THUG DRUGS! With a name like that, it has to be good! Even better than Smuckers (Age old ad slogan for jelly/jam)!  In this episode of the Pain Pod, we're going to dive into Thug Drug Policies, here in our country, and beyond. Come one, come all, to the Pain Pod!!! www.painguy.us  

Send Zorba a message!Dr. Zorba explains the importance of calcium scores to a caller, and how it relates to cholesterol. He reviews new research that shows PPIs (stomach acid-reducing drugs) may not increase stomach cancer risk. Zorba also discusses GLP-1 drugs vs. natural methods for losing weight, and shares his recipe for sinus rinse. The Grammar Cops chime in, and we hear a Mom Joke from one of our listeners.Support the showProduction, edit, and music by Karl Christenson Send your question to Dr. Zorba (he loves to help!): Phone: 608-492-9292 (call anytime) Email: askdoctorzorba@gmail.com Web: www.doctorzorba.org Stay well!

Send Zorba a message!Dr. Zorba explains the importance of calcium scores to a caller, and how it relates to cholesterol. He reviews new research that shows PPIs (stomach acid-reducing drugs) may not increase stomach cancer risk. Zorba also discusses GLP-1 drugs vs. natural methods for losing weight, and shares his recipe for sinus rinse. The Grammar Cops chime in, and we hear a Mom Joke from one of our listeners.Support the showProduction, edit, and music by Karl Christenson Send your question to Dr. Zorba (he loves to help!): Phone: 608-492-9292 (call anytime) Email: askdoctorzorba@gmail.com Web: www.doctorzorba.org Stay well!

Drugs and gangs have created an explosion in HIV cases in Fiji.This week on Battle Lines: Global Health Security, Arthur Scott-Geddes is joined by Sarah Newey, The Telegraph's correspondent in Bangkok who recently travelled to Fiji, and Dr Jason Mitchell, the head of the country's HIV task force.On the archipelago known as the gateway to the Pacific, Chinese triads, Mexican cartels, and Australian biker gangs are all involved in a booming methamphetamine trade.The result is that an island paradise is now home to the fastest-growing HIV epidemic on earth.Read Sarah's dispatch from Fiji:The island paradise with the world's fastest growing HIV epidemichttps://www.telegraph.co.uk/global-health/science-and-disease/fiji-island-paradise-with-the-worlds-fastest-growing-HIV-epidemic/Producer: Sophie O'SullivanExecutive Producer: Louisa WellsStudio Operator: Meghan Searle► Sign up to our most popular newsletter, From the Editor. Look forward to receiving free-thinking comment and the day's biggest stories, every morning. telegraph.co.uk/fromtheeditorContact us with feedback or ideas:battlelines@telegraph.co.uk@venetiarainey@ascottgeddes Hosted on Acast. See acast.com/privacy for more information.

Is chronic babesiosis finally getting the scientific attention it deserves?In this episode of Integrative Lyme Solutions, Dr. K sits down with Dr. Geoff Dow, CEO & President of Sixty Degrees Pharmaceuticals, to discuss a groundbreaking clinical trial targeting chronic babesiosis — a common and often overlooked Lyme co-infection. Originally developed for malaria prevention, the drug Tafenoquine (brand name Kodatef®) is now being studied for its potential to treat persistent Babesia infections and Lyme-related fatigue.They explore the science behind red blood cell parasites, how Babesia differs from malaria, why chronic babesiosis remains controversial, and what makes this new trial the first FDA-reviewed IND study focused on chronic disease. If you or a loved one struggle with Lyme-related fatigue, relapsing babesiosis, or limited treatment options, this conversation offers cautious optimism and a closer look at the future of targeted therapies.Key Takeaways:0:00 Introduction3:10 From Malaria Drug Development to Lyme Co-Infections6:45 How Babesia Infects Red Blood Cells and Causes Fatigue10:40 Why Chronic Babesiosis Is Still Controversial14:50 No FDA-Approved Drugs Specifically for Babesiosis18:30 New Clinical Trials for Chronic and Relapsing Babesiosis24:00 Measuring Fatigue as a Primary Endpoint in Chronic DiseaseResources Mentioned:Sixty Degrees Pharmaceuticals - https://www.sixtydegreespharma.comKodatef® (Tafenoquine) Information - Available via company website aboveMount Sinai (Clinical Trial Site) - https://www.mountsinai.orgYale Babesiosis Case Series (Referenced Study) - https://medicine.yale.eduMedical Disclaimer: This content is for educational purposes only and is not intended to diagnose, treat, cure, or replace professional medical advice. Always consult your physician or qualified healthcare provider regarding any medical condition or treatment decisions. _______________________________The Karlfeldt Center offers the most cutting-edge and comprehensive Lyme therapies. To schedule a Free 15-Minute Discovery Call with a Lyme Literate Naturopathic Doctor at The Karlfeldt Center, call 208-338-8902 or email info@TheKarlfeldtCenter.comCheck out Dr. K's Ebook: Breaking Free From Lyme: A Comprehensive Guide to Healing and Recovery here: https://store.thekarlfeldtcenter.com/products/breaking-free-from-lymeUse the code LYMEPODCAST for a 100% off discount!

 “Thug Drugs: Policy” THUG DRUGS! With a name like that, it has to be good! Even better than Smuckers (Age old ad slogan for jelly/jam)!  In this episode of the Pain Pod, we're going to dive into Thug Drug Policies, here in our country, and beyond. Come one, come all, to the Pain Pod!!! www.painguy.us

Watch on YouTube: https://youtube.com/live/kahCLPUxBv4 Watch on Rumble: https://rumble.com/v767axe-weight-loss-drugs-said-khodary-ramadan-nights-7-14472026.html Watch all the Ramadan Nights 1447/2026 programs: https://www.youtube.com/playlist?list=PLI2g1laHLLs4ym7Xw7YrZuL7I8_ricEsb Listen to the whole series: https://on.soundcloud.com/uJjyWnyNI9d8LOjDpX You can also listen LIVE on the Albayan Radio App: http://albayan.com.au/ To share in the reward and support Albayan Radio, please donate here: https://albayan.com.au/donate/

Ozempic and other GLP-1 drugs have had a major impact in their short time on the market—currently, one in eight Americans say that they have been on GLP-1 drugs. As tens of millions of people take these medications, anecdotal evidence has emerged that they have a positive effect on alcohol abuse and drug addiction. Researchers are starting to run trials of the drugs for these purposes, and some speculate that GLP-1 drugs could even affect addiction behaviors such as gambling and online shopping. The physician and New Yorker medical correspondent Dhruv Khullar spoke with scientists and patients. “Over the course of my reporting,” he tells David Remnick, “I became more and more bullish on the idea that these are actually going to be really important molecules for the treatment of addiction.” Dhruv Khullar's “Can Ozempic Cure Addiction?” was published on February 9th. New episodes of The New Yorker Radio Hour drop every Tuesday and Friday. Join host David Remnick as he discusses the latest in politics, news, and current events in conversation with political leaders, newsmakers, innovators, New Yorker staff writers, authors, actors, and musicians.

Listen to the whole episode at www.patreon.com/dopeypodcast Buy Dopeywood 2026 Tickets at https://www.showclix.com/event/dopeywood-2026 Today on Dopey! THIS WAS RECORDED PRE-BLIZZARD - Dave (still shaking off a cold) welcomes back Heart Attack Doug for a classic Tuesday Teaser — Upcoming storm hype, English-speaking country rankings (America/Australia top, Canada/England/South Africa debated), Australian Bush Mechanics docu-series rec, Dopey sticker sightings, and Doug's new band (cowboy hats, KKK rally jokes, bald head denial). Dave plugs Dopeywood 2026 (April 12 Comedy Store LA), Patreon (ad-free + Wednesday Zoom), Narcan/test strips, custom stickers (code DOPEY20), reads Spotify comments, talks Rolling Stone Yellow Balloon article (with Papa Smurf/Erin Khar help and more! Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Freya Von Doom joins Ralph Sutton and Aaron Berg and they discuss Freya Von Doom being only 4'8", trying to file for disability, working with Brickzilla, a game of Dinklage or Shrinkage where they guess if they image is of a little person's penis or a micro penis, and a game of Small Hands Flip Cup! Air Date: 02/18/26Support our sponsors!YoKratom.com - Check out Yo Kratom (the home of the $60 kilo) for all your kratom needs!To advertise your product or service on GaS Digital podcasts please go to TheADSide.com and click on "Advertisers" for more information!You can watch The SDR Show LIVE for FREE every Wednesday and Saturday at 9pm ET at GaSDigitalNetwork.com/LIVEOnce you're there you can sign up at GaSDigitalNetwork.com with promo code: SDR for discount on your subscription which will give you access to every SDR show ever recorded! On top of that you'll also have the same access to ALL the shows that GaS Digital Network has to offer!Follow the whole show on social media!Freya Von DoomInstagram: https://instagram.com/freyavondoomirlTwitter: https://twitter.com/Freya_Von_DoomAaron BergTwitter: https://twitter.com/aaronbergcomedyInstagram: https://instagram.com/aaronbergcomedyRalph SuttonTwitter: https://twitter.com/iamralphsuttonInstagram: https://www.instagram.com/iamralphsutton/Shannon LeeTwitter: https://twitter.com/IMShannonLeeInstagram: https://instagram.com/ShannonLee6982The SDR ShowTwitter: https://twitter.com/theSDRshowSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

The GLP-1 drug revolution has taken the medicine world by storm. I've done several episodes on the science of GLP-1s. But we've never done an episode like this before, where we talk to one of the most important people in charge of guiding the GLP-1 drug revolution. Our guest is Dave Ricks, the CEO of Eli Lilly, the largest pharmaceutical company in the world. First we talk about what makes the GLP-1 drug category special and the science that Lilly is doing to improve these drugs. Then, we talk about the pharmaceutical industry more broadly. How it works. How it could work better. And I don't shy away from the question that I think Pharma CEOs need to take much more seriously: If the pharmaceutical industry is theoretically more devoted than any other economic category to saving people's lives, why do Americans distrust it more than any other industry in the entire economy? Subscribe to our YouTube channel here: https://www.youtube.com/@PlainEnglishwithDerekThompson If you have questions, observations, or ideas for future episodes, email us at PlainEnglish@Spotify.com. Host: Derek ThompsonGuest: David RicksProducer: Devon Baroldi Learn more about your ad choices. Visit podcastchoices.com/adchoices

Trump Says He's Ready To Send Troops to Mexico NOW! The DEA Investigated Epstein for Smuggling Guns/Drugs For The CIA, Princeton Researchers Have Successfully Measured Humans Emitting ESP Electromagnetic Waves, Trump Set To Address Nation Tonight

Guess The News: Crazy Lawsuits, Killer Drugs & The Greatest TV Shows of All Time! Welcome back to another chaotic episode of the Working Perspectives Podcast! Tonight, Matt, Bern, and Liam are playing a high-stakes game of "Guess the Missing Piece." The Rules: Each host brings one bizarre, true news story or Top 10 list from around the globe. They read the story aloud but intentionally leave out the most crucial details. The other two hosts have exactly 4 minutes to grill the reader and guess the missing pieces before the clock runs out! In Tonight's Episode: Liam's TV Trivia: Liam challenges Matt and Bern to guess the Top 10 highest-rated TV shows of all time. Will they nail the classics or completely miss the mark? Bern's Bizarre Lawsuit: Bern brings a wild story about an adult who filed a massive lawsuit against a restaurant and a social media platform for ruining their life by posting a video of them without permission. Matt and Liam have to guess the country, the social media platform, the exact reason for the lawsuit, and the gender of the person involved! Matt's Deadly Data: Matt tests Bern and Liam's knowledge on a much darker topic, asking them to guess the Top 10 killer drugs in the United States. Who will conquer the clock and who is completely out of touch? Tune in to find out, and play along with us in the comments! Don't forget to LIKE, SUBSCRIBE, and leave a COMMENT below letting us know how many of the missing details you guessed right! ⏱️ Timestamps:

Dr. Mark Tarnopolsky's VO2 max was once 87.6 ml/kg/min — an elite-level mark few humans have reached. He's competed at three world championships in three different sports. He's also had three cardiac ablation surgeries, bled from his bowels after races, and watched his vision tunnel to a speck crossing a finish line. His story is a master class in where the line falls between peak performance and self-destruction.Now 63, Tarnopolsky is a neurologist, neuromuscular disease specialist, and supplement formulator who has channeled decades of elite athletic experience and hundreds of published studies into the idea that keeping metabolic throughput high is what protects us as we age.In this conversation with Dom D'Agostino, he shares practical strategies anyone can apply: why resistance training three times per week is non-negotiable after 50, why post-exercise nutrient timing improved performance in a simulated training camp with identical calories, why he says creatine belongs in nearly everyone's regimen, and why he personally takes his mitochondrial supplement stack situationally after hard efforts rather than daily.Questions Answered in This Episode:What is the only intervention proven to extend human lifespan — and by how much?At what point does endurance exercise become pro-aging — and what are the warning signs?What simple nutrient timing strategy improved performance with zero extra calories?How did a bodybuilder bar conversation lead to a published discovery about growth hormone and collagen?What muscle and bone costs of Ozempic aren't getting enough attention?Why did elite endurance athletes need nearly as much dietary protein as bodybuilders — and why were bodybuilders massively overconsuming?This conversation reframes the longevity debate around what's actually been proven in human clinical trials — not Petri dishes, not animal models, and not social media influencers.Special thanks to the sponsors of this episode:✅ Troscriptions – Get 10% off your first order with code METABOLICLINK here.✅ Toups and Co – Get 15% off your first order with code METABOLIC here.✅ iRestore – Get a huge discount on the Elite and the Illumina bundle here. ✅ MudWtr – Get up to 43% off + free shipping and a free rechargeable frother with code METABOLICLINK here.In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!Find us on social: Instagram Facebook YouTube LinkedIn Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

Send a textExplore the chaotic and visionary mind of Philip K. Dick, the legendary author behind Blade Runner, Total Recall, and Minority Report. In this episode of The Day's Grimm, Brian Michael Day and Thomas Grimm dive deep into a life that was arguably weirder than the science fiction stories it inspired.From the tragic infancy of his twin sister to his final days on the cusp of Hollywood fame, Philip K. Dick (PKD) lived on the edge of reality. We examine the "amphetamine-fueled" writing sessions where he produced up to 11 novels in two years, his five failed marriages, and the deep-seated paranoia that led him to believe the FBI was monitoring his every move.A central focus of this deep dive is the bizarre 1974 "2-3-74" event, where Dick claimed a pink beam of light transmitted divine information directly into his brain. This experience sparked an 8,000-page journal known as the Exegesis, where he wrestled with questions about ancient Rome, Gnosticism, and the nature of our reality—decades before "The Matrix" made these concepts mainstream.Whether he was a prophetic genius or a man struggling with substance-induced psychosis, PKD's influence on modern pop culture is undeniable. Join us as we break down the drugs, the delusions, and the legacy of the man who dared to ask: "What is real?" If you enjoyed this deep dive into PKD's chaotic life, hit the subscribe button and drop a comment below letting us know which author or historical figure we should cover next! TIMELINE: 00:00 - Introduction to Philip K. Dick 02:55 - The Tragic Death of His Twin Sister 06:00 - Childhood Phobias and Agoraphobia 08:20 - Early Writing Career and Poverty 09:33 - Amphetamine Use and Insane Output 11:33 - The FBI and the Blown-up Filing Cabinet 13:10 - Five Marriages Breakdown 15:55 - The 1974 Pink Light Experience 18:24 - The Exegesis and VALIS 21:30 - Blade Runner and Death 23:30 - Drug List and Writing Habits 27:42 - The Orange County Group and Steampunk[The Days Grimm Podcast Links]- YouTube: https://www.youtube.com/c/TheDaysGrimm- Our link tree: linktr.ee/Thedaysgrimm- GoFundMe account for The Days Grimm: https://gofund.me/02527e7c [The Days Grimm is brought to you by]Sadness & ADHD (non-medicated)

"Why are we paying $10,000 for a $30 drug?"My guest this week is Pramod John, a former Silicon Valley tech entrepreneur who entered the healthcare space to tackle the largest economic problem in the country: skyrocketing healthcare costs. Pramod quickly realized that healthcare's dysfunction is actually not a technology problem - it is a deeply ingrained problem with economic incentives.In this episode, we dive into the murky waters of Pharmacy Benefit Managers (PBMs) and why the traditional model is designed to drive up costs rather than lower them. We discuss the shocking statistics of drug spend (where 2% of people account for 55% of the costs), why FDA approval doesn't always mean a drug is effective (using the infamous Alzheimer's drug as an example), and the implications of recent fiduciary lawsuits like the one against J&J.Pramod explains how we can bring common sense back to healthcare by treating drugs like any other consumer purchase. By utilizing an "open market" drug management model, he argues that we can effectively replace traditional PBMs with transparent transaction processing software - saving plans 30% to 50% without relying on restrictive formularies or rebate games. Tune in this week for a clear roadmap for how to actually fix the irrational economics of our healthcare system.Thank you to our 2026 sponsors!ParetoHealth: ParetoHealth empowers midsize employers with a long-term solution to reduce volatility and lower overall health benefits costs. Visit ParetoHealth.com to learn more.Samaritan Fund: A program that connects those who need help to the support they need. We are proud to offer the Samaritan Fund Program. Visit SamaritanFundProgram.com to learn more.Vālenz Health: We're Vālenz Health, your partner in improving health literacy, reducing plan spend, and delivering high-value healthcare. Visit ValenzHealth.com to learn more.Imagine360: Imagine360 helps self-funded employers save on healthcare with smarter health plans. Cut expenses by 20-30% with custom solutions. Contact us today at Imagine360.com.Chapters:(00:00:00) Intro: Why We Talk About Cost Instead of Quality (00:02:42) From Silicon Valley & Defense Tech to McKesson (00:10:43) Why Healthcare is NOT a Technology Problem (00:15:53) Fiduciary Responsibility & The J&J Lawsuit (00:19:03) The Butter Knife vs. Pareto: The Math of Drug Spend (00:23:54) Building an "Open Market" Alternative to PBMs (00:29:40) Why Doctors Fly Blind on Drug Pricing & Formularies (00:35:42) FDA Approval vs. Real-World Efficacy (00:45:44) How to Actually Fix the Model: The Real-Time "Pause" (00:58:36) Why International Sourcing & PAPs Aren't the Fix (01:11:00) Replacing PBMs with Simple Transaction SoftwareKey Links for Social:@SelfFunded on YouTube for video versions of the podcast and much more - https://www.youtube.com/@SelfFundedListen/watch on Spotify - https://open.spotify.com/show/1TjmrMrkIj0qSmlwAIevKA?si=068a389925474f02Listen on Apple Podcasts - https://podcasts.apple.com/us/podcast/self-funded-with-spencer/id1566182286Follow Spencer on LinkedIn - https://www.linkedin.com/in/spencer-smith-self-funded/Follow Spencer on Instagram - https://www.instagram.com/selffundedwithspencer/

Robert's LinkedIn: https://www.linkedin.com/in/robert-s-goldman/My substack FREE: https://substack.com/@dansfera1?r=27gh4e&utm_medium=ios&utm_source=profileInato: https://go.inato.com/3VnSro6CRIO: http://www.clinicalresearch.ioMy PatientACE recruitment company: https://patientace.com/Join me at my conference! http://www.saveoursites.comText Me: (949) 415-6256Listen on Spotify: https://open.spotify.com/show/7JF6FNvoLnBpfIrLNCcg7aGET THE BOOK! https://www.amazon.com/Comprehensive-Guide-Clinical-Research-Practical/dp/1090349521/ref=sr_1_1?keywords=Dan+Sfera&qid=1691974540&s=audible&sr=1-1-catcorrText "guru" to 855-942-5288 to join VIP list!My blog: http://www.TheClinicalTrialsGuru.comMy CRO and Site Network: http://www.DSCScro.comMy CRA Academy: http://www.TheCRAacademy.comMy CRC Academy: http://www.TheCRCacademy.comLatinos In Clinical Research: http://www.LatinosinClinicalResearch.comThe University Of Clinical Research: https://www.theuniversityofclinicalresearch.com/My TikTok: DanSfera

drugs

"Why are we paying $10,000 for a $30 drug?"My guest this week is Pramod John, a former Silicon Valley tech entrepreneur who entered the healthcare space to tackle the largest economic problem in the country: skyrocketing healthcare costs. Pramod quickly realized that healthcare's dysfunction is actually not a technology problem - it is a deeply ingrained problem with economic incentives.In this episode, we dive into the murky waters of Pharmacy Benefit Managers (PBMs) and why the traditional model is designed to drive up costs rather than lower them. We discuss the shocking statistics of drug spend (where 2% of people account for 55% of the costs), why FDA approval doesn't always mean a drug is effective (using the infamous Alzheimer's drug as an example), and the implications of recent fiduciary lawsuits like the one against J&J.Pramod explains how we can bring common sense back to healthcare by treating drugs like any other consumer purchase. By utilizing an "open market" drug management model, he argues that we can effectively replace traditional PBMs with transparent transaction processing software - saving plans 30% to 50% without relying on restrictive formularies or rebate games. Tune in this week for a clear roadmap for how to actually fix the irrational economics of our healthcare system.Thank you to our 2026 sponsors!ParetoHealth: ParetoHealth empowers midsize employers with a long-term solution to reduce volatility and lower overall health benefits costs. Visit ParetoHealth.com to learn more.Samaritan Fund: A program that connects those who need help to the support they need. We are proud to offer the Samaritan Fund Program. Visit SamaritanFundProgram.com to learn more.Vālenz Health: We're Vālenz Health, your partner in improving health literacy, reducing plan spend, and delivering high-value healthcare. Visit ValenzHealth.com to learn more.Imagine360: Imagine360 helps self-funded employers save on healthcare with smarter health plans. Cut expenses by 20-30% with custom solutions. Contact us today at Imagine360.com.Chapters:(00:00:00) Intro: Why We Talk About Cost Instead of Quality (00:02:42) From Silicon Valley & Defense Tech to McKesson (00:10:43) Why Healthcare is NOT a Technology Problem (00:15:53) Fiduciary Responsibility & The J&J Lawsuit (00:19:03) The Butter Knife vs. Pareto: The Math of Drug Spend (00:23:54) Building an "Open Market" Alternative to PBMs (00:29:40) Why Doctors Fly Blind on Drug Pricing & Formularies (00:35:42) FDA Approval vs. Real-World Efficacy (00:45:44) How to Actually Fix the Model: The Real-Time "Pause" (00:58:36) Why International Sourcing & PAPs Aren't the Fix (01:11:00) Replacing PBMs with Simple Transaction SoftwareKey Links for Social:@SelfFunded on YouTube for video versions of the podcast and much more - https://www.youtube.com/@SelfFundedListen/watch on Spotify - https://open.spotify.com/show/1TjmrMrkIj0qSmlwAIevKA?si=068a389925474f02Listen on Apple Podcasts - https://podcasts.apple.com/us/podcast/self-funded-with-spencer/id1566182286Follow Spencer on LinkedIn - https://www.linkedin.com/in/spencer-smith-self-funded/Follow Spencer on Instagram - https://www.instagram.com/selffundedwithspencer/

Hans en Ria hebben een besluit genomen over zijn toekomst. Ze vertellen erover aan de keukentafel. Ria kijkt ernaar uit om meer vrijheid te hebben. Hans geeft een afscheidsconcert met zijn zangkoor. Ploeterend, geholpen door zijn zangvrienden, zingt hij nog één keer zijn lievelingsnummer.Presentatie: Enzo van SteenbergenProductie: Nina van Hattum & Mirjam van ZuidamMontage: Jan Paul de Bondt & Nina van HattumZie het privacybeleid op https://art19.com/privacy en de privacyverklaring van Californië op https://art19.com/privacy#do-not-sell-my-info.

Op 65-jarige leeftijd krijgt de vrolijke verwarmingsmonteur Hans Goebertus de diagnose alzheimer. Hans en zijn vrouw Ria vertellen dat Hans al snel van alles niet meer kan, dochter Loes praat over het moment dat ze hoorde dat haar vader ziek was. Met Hans gaan we naar zijn zangkoor, waar hij zijn favoriete nummer zingt: The Wild Rover. Presentatie: Enzo van SteenbergenProductie: Nina van Hattum & Mirjam van ZuidamMontage: Jan Paul de Bondt & Nina van HattumZie het privacybeleid op https://art19.com/privacy en de privacyverklaring van Californië op https://art19.com/privacy#do-not-sell-my-info.

Hans neemt ons mee op een wandeling door de buurt waar hij al veertig jaar woont. Hij kende ooit alle kroegen, alle winkels en alle gebouwen. Maar opeens weet hij niet meer waar hij is. Het moment dat hij niet meer zelf over straat kan komt steeds dichterbij. Er moet over zijn toekomst worden gepraat. Maar hoe doe je dat, als je weet dat alles alleen maar minder wordt? En durft Hans wel na te denken over het einde?Presentatie: Enzo van SteenbergenProductie: Nina van Hattum & Mirjam van ZuidamMontage: Jan Paul de Bondt & Nina van HattumZie het privacybeleid op https://art19.com/privacy en de privacyverklaring van Californië op https://art19.com/privacy#do-not-sell-my-info.

Hans wil graag kijken bij een verpleeghuis voor mensen met dementie, maar eenmaal daar vliegt het hem allemaal aan. Langzaam wordt hij steeds afhankelijker van zijn familie en zijn vrienden. Dochter Loes realiseert zich dat haar ouders het moeilijk hebben. Tijdens een fietsvakantie blijkt dat de relatie van Hans met zijn beste vrienden erg is veranderd. Iedereen probeert op zijn eigen manier een antwoord te vinden op de vraag: hoe kan ik Hans het beste helpen?Presentatie: Enzo van SteenbergenProductie: Nina van Hattum & Mirjam van ZuidamMontage: Jan Paul de Bondt & Nina van HattumZie het privacybeleid op https://art19.com/privacy en de privacyverklaring van Californië op https://art19.com/privacy#do-not-sell-my-info.

Het is de zomer van 2017. Vier jaar nadat Hans de diagnose Alzheimer heeft gekregen. Ria en Hans fietsen met een groep vrienden door Spanje. Ze fietsen over bergen en genieten. Maar dan gaat het mis. Niet met Hans, maar met Ria. Ze kan de zorg voor Hans niet meer aan en realiseert zich dat haar relatie met Hans nooit meer hetzelfde zal zijn. Want wat blijft er over van een relatie als je geliefde aftakelt?Presentatie: Enzo van SteenbergenProcuctie: Nina van Hattum & Mirjam van ZuidamMontage: Jan Paul de Bondt & Nina van HattumZie het privacybeleid op https://art19.com/privacy en de privacyverklaring van Californië op https://art19.com/privacy#do-not-sell-my-info.

Jason Abreu grew up in a good family, on track to become a lawyer, until the recession blew up his plans and pushed him into the New York City nightlife scene. What started as legit nightclub promoting slowly turned into moving drugs through NYC clubs, big money, fast nights, and a double life he thought he had under control. Then undercover cops took him down, and Jason was sent to New York state prison. He got out, went right back to the game, and got caught again, earning a second trip upstate. In this episode, Jason sits down with me and breaks down exactly how it happened: the first bad decision, how the nightclub world really works, the rush of easy money, the takedown, and what New York state prison is actually like on the inside, from daily politics to survival _____________________________________________ #NYC #NewYorkStatePrison #PrisonLife #UndercoverCops #DrugDealing #NightclubCrime #TrueCrime #prisonstories _____________________________________________ Thank you to 300 LETTERS for sponsoring this episode: Visit http://300letters.org/ to learn more or get support. Your donation to 300 Letters is an investment in safer neighborhoods & healthier families. _____________________________________________ Connect with Jason Abreu: Instagram: @madeupnorthnyc Podcast IG: @offthecountpodcast _____________________________________________ Hosted, Executive Produced & Edited By Ian Bick: https://www.instagram.com/ian_bick/?hl=en https://ianbick.com/ _____________________________________________ Shop Locked In Merch: http://www.ianbick.com/shop _____________________________________________ Timestamps: 00:00 From Prison Transfer To State Property 00:44 Jason Abreu: Good Kid, Good Family 02:23 Wanted To Be A Lawyer, Stayed Out Of Trouble 04:34 How NYC Nightlife Pulled Him Off Track 06:14 Crash, Drugs & Ego: The Downward Spiral 11:12 Getting Shot In The Club & Feeling Invincible 16:47 Ignoring Trauma & Diving Deeper Into Nightlife 19:43 Drugs, Greed & His First Indictment 23:56 Undercover Cop Setup & The Arrest 27:38 Arrests, Bail Money & Mounting Consequences 33:39 First Time On Rikers Island 37:11 Plea Deal, Charges & Sentencing Explained 39:50 Upstate Prison Life: Politics & Violence 51:47 Survival Rules, OGs & Getting Ready For Release 54:07 Re-Entry, No Money & Old Temptations 59:13 Second Arrest & The Ultimate Betrayal 01:04:18 Resentment, Forgiveness & Coming Back To Prison 01:09:19 Second Bid: Pandemic Lockdowns Inside 01:12:21 Finding Purpose & Breaking His Own Cycle 01:15:56 “Made Up North” – Turning His Story Into A Movement 01:19:00 Avoiding Triggers & Staying Out Of The Game 01:22:31 Rebuilding Life, Writing The Book & Giving Back 01:24:41 Why His Story Matters & Final Message To Viewers Learn more about your ad choices. Visit megaphone.fm/adchoices

What does heroin actually do to a human being — and why are so many young Africans falling into addiction? In this raw and unfiltered conversation, Steve Khald Maridadi a Rwandan filmmaker, opens up about heroin addiction, cocaine, laced marijuana, recovery, psych wards, and the system that failed him. We explore how drug addiction works biologically and psychologically, why jailing addicts may be the wrong solution, and how stigma pushes addiction underground.Sponsors: Threat Informat - https://threatinformant.io/.                                                    Akagera Medicines- https://www.akageramedicines.com/ Join our Patreon to enjoy ad-free viewing https://www.patreon.com/cw/TheLongFormPod or support us via our MTN Mobile Money Code 95462 or directly to our phone number: +250795462739 Visit Sanny Ntayombya's Official Website: https://sannyntayombya.com

"Ever moment, every day is worth celebrating." Somer LoveSomer Love has spent her life choosing hope, dreaming big, and showing up fully for each day. Diagnosed with cystic fibrosis at just 11 months old, Somer has grown into a powerful and compassionate advocate for the CF community.Guided by her belief that “Every moment, every day is worth celebrating,” Somer brings joy and purpose into everything she does. She often reminds others that “laughter is key,” a mindset that has helped carry her, and those around her, through the challenges of life with cystic fibrosis.Through her work, Somer is dedicated to raising awareness, educating others, and offering hope, especially to families navigating a new CF diagnosis. In 2001, she founded Love to Breathe®, a platform created to educate, spread awareness about cystic fibrosis, and share love and connection around the world.Big on birthdays, Somer's parents made celebration part of her story in an unforgettable way. Every year, they placed Somer's photo on a billboard. What began as a birthday tradition became something much bigger, raising awareness about cystic fibrosis in a way that stops people in their tracks. What that billboard did for awareness will give you chills. It's something you will never forget. You'll have to listen to the podcast to hear the story!Somer knows that fighting CF isn't something anyone can do alone. Her journey is deeply rooted in the strength of her support system and the community that stands beside her. She continues to advocate not only for her own future, but for a cure, for everyone living with cystic fibrosis.Somer sums up the reason to advocate. This quote is on her website: "The goal isn't to live forever, but to create something that will"-Chuck Palahniuk Please like, subscribe, and comment on our podcasts!Please consider making a donation: https://thebonnellfoundation.org/donate/The Bonnell Foundation website:https://thebonnellfoundation.orgEmail us at: thebonnellfoundation@gmail.com Watch our podcasts on YouTube: https://www.youtube.com/@laurabonnell1136/featuredThanks to our sponsors:Vertex: https://www.vrtx.comViatris: https://www.viatris.com/enRead us on Substack: https://substack.com/@lstb?utm_campaign=profile&utm_medium=profile-pageWatch our trailer of Embracing Egypt: https://youtu.be/RYjlB25Cr9Y

Dr. Galati starts with the big win for Team USA in the Hockey game this morning. He also shares his thoughts on second opinions in regard to health issues. Dr. Galati talks about the Nancy Guthrie situation and disuses whether older parents should be living by themselves. He also has a few articles of intertest on wight loss drugs and garlic supplements. 

Evelyn Kelly joins Business Builders for a powerful conversation about rare disease medicine, scaling a global consultancy, and what it really means to build a business with purpose.From starting at her kitchen table in 2017 with no formal plan, to growing Orphan Drug Consulting from €250,000 to €5 million in just four years, Evelyn shares how she built a specialist pharma consultancy that has helped over 70 companies launch medicines in more than 100 countries.But this isn't just a growth story.Evelyn works in the world of orphan drugs — treatments for rare diseases, many of which affect children. With over 7,000 rare diseases globally and fewer than 10% having approved treatments, she explains the regulatory, commercial and supply chain realities behind getting life-saving medicines to patients.The conversation explores what most people never see: clinical trial constraints, reimbursement battles across Europe, US pricing pressure, post-Brexit complexity, and the volatility currently hitting the biotech investment market.Alongside the technical depth, Evelyn reflects on leadership — absorbing hard feedback, building processes that allow scale, being responsible for other people's livelihoods, and why managing risk isn't about fear, but about stability.This episode is a grounded, high-level look at the intersection of purpose and process — and what it takes to build a resilient business in one of the most complex industries in the world.

What happens to consumers, and to the food and wellness industries, when millions of people come off GLP-1 medication?With GLP-1 drugs surging in popularity, the food industry is already grappling with something far more complex than simply weightloss: who is this consumer, what do they need while on the medication, and crucially, what do they need when they stop?In this episode of the Food Matters Live podcast, recorded at our Ascot event, our panel of experts dig into the physiology, the food innovation opportunity, and the gaps the industry is not yet filling. They explore how GLP-1 drugs alter taste and texture perception, why the craving for sweetness and alcohol diminishes whilst on the drugs, and what nutrient-dense, small-format product innovation looks like for a consumer eating far less.They also look to the future, when patients come off medication, as the critical, underleveraged opportunity for functional food, probiotics, and fibre innovation. 

Drugs are for humans

A former Chicago-area teacher is speaking out about what he witnessed inside America's public school system — and the stories are shocking.Geno Young, author of Sex, Drugs, and Illiteracy: The Death of Education in America, joins the show to reveal the lack of accountability, declining academic standards, classroom discipline breakdowns, and the funding incentives driving many of today's education policies.From grade manipulation and administrative pressure to sexual misconduct and falling literacy rates, this interview takes you inside the realities many teachers are afraid to discuss publicly.What's really happening in public schools? And what does it mean for the future of education in America?Watch now for a firsthand look at the growing education crisis.Get Geno's book HERE: Sex, Drugs, and Illiteracy: The Death of Education In AmericaSubscribe and stay tuned for new episodes every weekday!Follow us here for more daily clips, updates, and commentary:YoutubeFacebookInstagramTikTokXLocalsMore InfoWebsite

Jim McTague reports Lancaster County reflects the national 1.4 percent GDP slowdown with flat retail, consumer price fatigue, and plummeting restaurant traffic due to rising costs and weight-loss drugs, while Washington DC lobbying and local health and construction sectors remain strong. 51879 GRAND ARMY OF THE REPUBLIC

Jordan Carlos joins Ralph Sutton and Aaron Berg and they discuss Aaron getting cut out of the Couples' Therapy TV show, birth order and growing up as a middle child, studying art at Brown, writing jokes for other people, first acting gig was playing a dead guy, getting n the Colbert Report, filming Black Mirror in Brazil, Jordan Carlos' book Choreplay: The Marriage-Saving Magic of Getting Your Head Out of Your Ass, the low bar on pleasing women, wanting to cancel Green Eggs And Ham, the new game Dr. Seuss Marriage Advice where the guys try to resolve common marriage disputes with rhymes, Jordan Carlos' first concert, first drug and first sexual experience and so much more! Air Date: 2/14/2026Support our sponsors!Valor Sciences - Support us by shopping at https://valorsciences.com/amb/24/ and use code SDR to get 10% off any orderTo advertise your product or service on GaS Digital podcasts please go to TheADSide.com and click on "Advertisers" for more information!You can watch The SDR Show LIVE for FREE every Wednesday and Saturday at 9pm ET at GaSDigitalNetwork.com/LIVEOnce you're there you can sign up at GaSDigitalNetwork.com with promo code: SDR for discount on your subscription which will give you access to every SDR show ever recorded! On top of that you'll also have the same access to ALL the shows that GaS Digital Network has to offer!Follow the whole show on social media!Jordan CarlosTwitter: https://twitter.com/JordanCarlosInstagram: https://instagram.com/JordanCarlosOfficialRalph SuttonTwitter: https://twitter.com/iamralphsuttonInstagram: https://www.instagram.com/iamralphsutton/Shannon LeeTwitter: https://twitter.com/IMShannonLeeInstagram: https://instagram.com/ShannonLee6982The SDR ShowTwitter: https://twitter.com/theSDRshowSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

(Repeat episode) - SEASON 11 Coming FEB 27th! My website My Instagram

We are the Mother Aphid! Our experience with drugged out cinema in our theme “Rrrrrreal f*ckin' High on Drugs” takes us to the itchiest corner of cinema with master filmmaker William Friedkin's BUG! We have arguably one of our richest film discussions digging into this fever dream of meth-soaked cinema and along the way we talk more about Cody's Only Child Chair, Super Bowl nonsense, and some classic blindspots!   Go to patreon.com/SHUDcast where you can sign up for all kinds of extra goodies!   00:00 - 15:15ish - Intros - Super Bowl commercials + trailers, Cody's Only Child Chair   15:15ish - 39:00ish - The other stuff we watched this time!   Curtis - Hard Boiled, Hold the Dark, Goat, The Worst Person in the World   Austin - Train Dreams   Lucas - The Northman   Cody - Knight of the Seven Kingdoms, Jeopardy, Sisu: Road to Revenge   39:00ish - 1:15:30ish - BUG - SHUDdown and discussion!   1:15:30ish - End - The fourth and final film of “Rrrrreal f*cking High on Drugs” brought to you by Lucas!

Scott Deitche is a mob historian and bestselling author of Cigar City Mafia: A Complete History of the Tampa Underworld, The Silent Don: The Criminal Underworld of Santo Trafficante Jr., and Hitmen: The Mafia, Drugs, and the East Harlem Purple Gang. He has written dozens of articles on organized crime and has been featured on The Discovery Channel, The History Channel, A&E, C-SPAN, Oxygen, American Heroes Channel, and national news and radio programs. Scott is also a member of the Mob Museum Advisory Council and leads Tampa Mafia tours.He explains:◼️How Tampa became one of the most powerful Mafia cities in America◼️Why over 50 gangland murders and assassination attempts erupted during the Bolita wars◼️How the CIA secretly partnered with the Mafia to try to assassinate Fidel Castro◼️Why the JFK assassination conspiracy still points back to Tampa figures◼️What ultimately ended organized crime's grip on Tampa00:00 - Ybor Tunnels01:51 - Scott Deitche06:07 - Tampa Mafia10:14 - Bolita19:18 - Charlie Wall30:53 - Mafia Tours33:16 - JFK Assassination37:34 - Mafia Family Members

A report came out recently that stated that an abnormal amount of cocain found in the water in one very specific city in the United States. The crazy part is, it isn't a city that you would expect!It's Throwback Thrusday so we have to play our favorite game, Throwback Trivia! Things get a little wild tough when some over confidence in the room starts to backfire...A guy recently got back some unfavorable medical reports. The doctor said there wan't much to worry about but his wife thought differently... She decided to put him on a diet which got him thinking... what would happen if he did that to her...

Madeleine Finlay sits down with science editor Ian Sample and science correspondent Nicola Davis to discuss three eye-catching stories, including the impact of a powerful psychedelic on depression, answers on the death of Russian opposition leader Alexei Navalny, and an explanation to the mystery of why humans have chins. Help support our independent journalism at theguardian.com/sciencepod

Send me a question or story!Janus kinase (JAK) inhibitors have become a cornerstone in managing pruritic and allergic skin disease in dogs by targeting the JAK-STAT signaling pathway, which transmits itch and inflammatory cytokine signals. With so many medications hitting the market, it is important to understand the differences between all of the different JAK inhibitors in veterinary medicine.Apoquel (oclacitinib) has been in the veterinary field the longest with over a decade of use. However, Zenrelia (ilunocitinib) has been available in many countries for over a year. Additionally, Numelvi (atinvicitinib) has recently become available in Europe and will hit the market in the United States very soon (with others to follow). Learn about the differences in these medications and why it is important to become comfortable with all of them on this week's episode of The Derm Vet podcast.Timestamps00:00 Intro01:35 JAK Inhibitor Basics02:35 What are JAK Receptors03:31 Apoquel and Zenrelia 05:20 Numelvi 07:57 How To Tell If a Pet Is Atopic 09:12 Are JAK Inhibitors Safe with Neoplasia11:32 What Does JAK Selectivity Mean 13:47 Common Side-Effects of JAK Inhibitors 17:01 Using JAK Inhibitors Off-Label18:51 Outro

Retired agent Jerry Spurgers reviews his investigation of the mysterious disappearance of federal witness Susan Cooper from Malvern, Arkansas. The case involved drug conspiracy, witness intimidation, and murder. Jerry investigated the case with a team of local officers, sheriff's deputies, and an intelligence analyst by using traditional police skills and new technologies. As a former member of the Little Rock Division's Evidence Response Team and an experienced death investigator, he also reviews the steps taken to collect evidence at a murder or accidental death. Jerry is the author of Murder at Midnight: The FBI's Battle with Violence and Drugs in a Small Southern Town, a true crime book about the investigation. He served in the FBI for 24 years. Check out episode show notes, photos, and related articles: https://jerriwilliams.com/388-jerry-spurgers-disappearance-and-murder-of-federal-witness-death-crime-scenes/       Join my Reader Team to get the FBI Reading Resource - Books about the FBI, written by FBI agents, the 20 clichés about the FBI Reality Checklist, and keep up to date on the FBI in books, TV, and movies via my monthly email. Join here. http://eepurl.com/dzCCmL    Buy me a coffee - https://www.buymeacoffee.com/JerriWilliams   Check out my FBI books, non-fiction and crime fiction, available as audiobooks, ebooks and paperbacks wherever books are sold. https://jerriwilliams.com/books/e

Drugs up your butt!See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Caitlin V joins Ralph Sutton and Chris Faga and they discuss teaching masturbation meditation, Caitlin V's origin story, her viral squirting video and the truth about squirting, orgasms vs ejaculation, how many positions there really are, a game of Healthy, Red Flag or Serial Killer, Caitlin's book Harder, Better, Longer, Stronger, Caitlin V's first concert, first drug and first sexual experience and so much more!Air Date: 02/07/26Support our sponsors!YoKratom.com - Check out Yo Kratom (the home of the $60 kilo) for all your kratom needs!To advertise your product or service on GaS Digital podcasts please go to TheADSide.com and click on "Advertisers" for more information!You can watch The SDR Show LIVE for FREE every Wednesday and Saturday at 9pm ET at GaSDigitalNetwork.com/LIVEOnce you're there you can sign up at GaSDigitalNetwork.com with promo code: SDR for discount on your subscription which will give you access to every SDR show ever recorded! On top of that you'll also have the same access to ALL the shows that GaS Digital Network has to offer!Follow the whole show on social media!Caitlin VInstagram: https://instagram.com/caitlinvictoriousxLink Tree: https://linktr.ee/caitlinvictoriousxChris FagaInstagram: https://instagram.com/ChrisFromBKLYNRalph SuttonTwitter: https://twitter.com/iamralphsuttonInstagram: https://www.instagram.com/iamralphsutton/Shannon LeeTwitter: https://twitter.com/IMShannonLeeInstagram: https://instagram.com/ShannonLee6982The SDR ShowTwitter: https://twitter.com/theSDRshowSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.