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Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.07.06.547961v1?rss=1 Authors: Wetekam, J., Hechavarria, J. C., Lopez-Jury, L., Gonzalez-Palomares, E., Koessl, M. Abstract: Deviance detection describes an increase of neural response strength caused by a stimulus with a low probability of occurrence. This ubiquitous phenomenon has been reported for multiple species, from subthalamic areas to auditory cortex. While cortical deviance detection has been well characterised by a range of studies covering neural activity at population level (mismatch negativity, MMN) as well as at cellular level (stimulus-specific adaptation, SSA), subcortical deviance detection has been studied mainly on cellular level in the form of SSA. Here, we aim to bridge this gap by using noninvasively recorded auditory brainstem responses (ABRs) to investigate deviance detection at population level in the lower stations of the auditory system of a hearing specialist: the bat Carollia perspicillata. Our present approach uses behaviourally relevant vocalisation stimuli that are closer to the animals' natural soundscape than artificial stimuli used in previous studies that focussed on subcortical areas. We show that deviance detection in ABRs is significantly stronger for echolocation pulses than for social communication calls or artificial sounds, indicating that subthalamic deviance detection depends on the behavioural meaning of a stimulus. Additionally, complex physical sound features like frequency- and amplitude-modulation affected the strength of deviance detection in the ABR. In summary, our results suggest that at population level, the bat brain can detect different types of deviants already in the brainstem. This shows that subthalamic brain structures exhibit more advanced forms of deviance detection than previously known. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC
Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.07.03.547519v1?rss=1 Authors: Garcia-Rosales, F., Schaworonkow, N., Hechavarria, J. C. Abstract: Neural oscillations are associated with diverse computations in the mammalian brain. The waveform shape of oscillatory activity measured in cortex relates to local physiology, and can be informative about aberrant or dynamically changing states. However, how waveform shape differs across distant yet functionally and anatomically related cortical regions is largely unknown. In this study, we capitalize on simultaneous recordings of local field potentials (LFPs) in the auditory and frontal cortices of awake Carollia perspicillata bats to examine, on a cycle-by-cycle basis, waveform shape differences across cortical regions. We find that waveform shape differs markedly in the fronto-auditory circuit even for rhythmic activity in comparable frequency ranges (i.e. in the delta and gamma bands) during spontaneous activity. In addition, we report consistent differences between areas in the variability of waveform shape across individual cycles. A conceptual model predicts higher spike-spike and spike-LFP correlations in regions with more asymmetric shape, a phenomenon that was observed in the data: spike-spike and spike-LFP correlations were higher in frontal cortex. The model suggests a relationship between waveform shape differences and differences in spike correlations across cortical areas. Altogether, these results indicate that oscillatory activity in frontal and auditory possess distinct dynamics related to the anatomical and functional diversity of the fronto-auditory circuit. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC
Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2022.10.28.514155v1?rss=1 Authors: Deane, K. E., Garcia-Rosales, F., Klymentiev, R., Hechavarria, J. C., Happel, M. F. K. Abstract: The brains of black 6 mice (Mus musculus) and Seba's short-tailed bats (Carollia perspicillata) weigh roughly the same and share the mammalian neocortical laminar architecture. Bats have highly developed sonar calls and social communication and are an excellent neuroethological animal model for auditory research. Mice are olfactory and somatosensory specialists and are used frequently in auditory neuroscience, particularly for their advantage of standardization and genetic tools. Investigating their potentially different general auditory processing principles would advance our understanding of how the ecological needs of a species shape the development and function of the mammalian nervous system. We compared two existing datasets, recorded with linear multichannel electrodes down the depth of the primary auditory cortex (A1) while awake, across both species while presenting repetitive stimulus trains with different frequencies (~5 and ~40 Hz). We found that while there are similarities between cortical response profiles in bats and mice, there was a better signal to noise ratio in bats under these conditions, which allowed for a clearer following response to stimuli trains. This was most evident at higher frequency trains, where bats had stronger response amplitude suppression to consecutive stimuli. Phase coherence was far stronger in bats during stimulus response, indicating less phase variability in bats across individual trials. These results show that although both species share cortical laminar organization, there are structural differences in relative depth of layers. Better signal to noise ratio in bats could represent specialization for faster temporal processing shaped by their individual ecological niches. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC
#242 – On today's episode, Anthony & Bryan are joined by personal trainer, strength coach, nutritionist and owner of The Bond Miami, Waldo Hechavarria. Waldo shares his story on how he started his career studying in the medical field but once he graduated realized he didn't have a passion for it and decided to apply to be a trainer at Equinox, which had just opened at the time. There, he found his passion for health and fitness and loved working with people in a one on one setting. Waldo expresses how personal training allowed him to grow as an individual and helping others become the best versions of themselves motivated him to keep going. Later, they discuss the ups and downs of business relationships and how to be an opportunist when things go wrong and see how you can learn from each situation instead of letting it take you down.
Brenda came on and is the sweetest lady. We talked all about early marriage, the military, her being pregnant, what life is California is like and family. We also discussed businesses and time management. Tell us in the comments what your preferred work schedule is. Tune in and let me know what you think! --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app
Dr. Mike Crovetti chats with bilateral knee replacement patient Glen Hechavarria as he shares his ‘real deal' story of having both knees replaced within a 5 week period of time. Glen has been in the restaurant business since he was 15 and shares what it was like living with continuous knee pain including having to […] The post Crovetti Orthopaedics and Sports Medicine Podcast #8: THE REAL DEAL with Patient Glen Hechavarria appeared first on Crovetti Orthopaedics.
Extracto de la directa del 27 de octubre 2020
Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.05.05.078667v1?rss=1 Authors: Garcia-Rosales, F., Lopez-Jury, L., Gonzalez-Palomares, E., Cabral-Calderin, Y., Koessl, M., Hechavarria, J. C. Abstract: Neural oscillations are at the core of important computations in the mammalian brain. Interactions between oscillatory activities in different frequency bands, such as delta (1-4 Hz), theta (4-8 Hz), or gamma (>30 Hz), are a powerful mechanism for binding fundamentally distinct spatiotemporal scales of neural processing. Phase-amplitude coupling (PAC) is one such plausible and well-described interaction, but much is yet to be uncovered regarding how PAC dynamics contribute to sensory representations. In particular, although PAC appears to have a major role in audition, the characteristics of coupling profiles in sensory and integration (i.e. frontal) cortical areas remain obscure. Here, we address this question by studying PAC dynamics in the frontal-auditory field (FAF; an auditory area in the bat frontal cortex) and the auditory cortex (AC) of the bat Carollia perspicillata. By means of simultaneous electrophysiological recordings in frontal and auditory cortices examining local-field potentials (LFPs), we show that the amplitude of gamma-band activity couples with the phase of low-frequency LFPs in both structures. Our results demonstrate that the coupling in FAF occurs most prominently in delta/high-gamma frequencies (1-4/75-100 Hz), whereas in the AC the coupling is strongest in the theta/low-gamma (2-8/25-55 Hz) range. We argue that distinct PAC profiles may represent different mechanisms for neuronal processing in frontal and auditory cortices, and might complement oscillatory interactions for sensory processing in the frontal-auditory cortex network. Copy rights belong to original authors. Visit the link for more info
Rays VP of Baseball Operations, Chaim Bloom called the Ronnie & TKras Show today to discuss Hechavarria trade talks, Machado to L.A, & the future of the roster.
Marc Topkin of the Tampa Bay Times joined Ron Diaz and Jay Recher on Tuesday afternoon to talk all things Rays. Marc told the guys how cool it has been to see Blake Snell take in his first all star experience. Marc also told us how the Manny Machado trade could clear up the market for Adeiny Hechavarria.
ESPN MLB Analyst Tim Kurkjian shares his thoughts on the Rays pitching project & where he thinks Ramos and Hechavarria are being traded to! Hypothetically, of course...
The Rays lose 3 of 4 in New York as they can't figure out the Yankees pitching, the activated Adeiny Hechavarria on Sunday and moved Willy Adames to 2nd base for the day and Hechavarria was one of the stars in Sunday's win. Plus golf is outraged at Phil Mickelson at the US Open as he takes a 2-stroke penalty to avoid having his ball roll down the hill, the Bucs OJ Howard could be ready for a breakout season and some upsets at the World Cup. Today's episode is presented by Continental Wholesale Diamonds at http://continentalwholesalediamonds.com See acast.com/privacy for privacy and opt-out information.
Marc Topkin joined us to talk all things Rays. He recapped the heart breaking loss for the Rays yesterday. He also gave us an update on when Nathan Eovaldi could be back and gave us an update on the Hechavarria trade rumors.
Marc Topkin of the Tampa Bay Times joined us to talk all things Rays. Marc recapped the great start from Jake Faria last night. He also went in depth on Daniel Robertson's recent success. Marc also got into the rumors about if Corey Seager's injury could have the Rays dealing with the Dodgers again.
Steve Carney joined us to discuss the rumors that the Rays might not be done dealing.
Will Adeiny Hechavarria be a major contributor in 2018? MLB.com’s Tim McMaster and Rays reporter Bill Chastain discuss Hechavarria’s importance to the team and if Brendan McKay could be both a first baseman and a closer in the future.
Will Adeiny Hechavarria be a major contributor in 2018? MLB.com's Tim McMaster and Rays reporter Bill Chastain discuss Hechavarria's importance to the team and if Brendan McKay could be both a first baseman and a closer in the future.
Alex Cobb went eight scoreless innings while Adeiny Hechavarria drove in two runs in his Rays debut in a 4-2 win in extras. Hechavarria and Kevin Cash break down the extra-innings win after the game.
Kevin Cash talks about trading for Hechavarria, Beckham's spot, & the Pirates series
Hey Look! In a somewhat on time podcast Tom and Johnny sit down to discuss our beloved bluebirds. Topics range on the GM's comments on the LF battle, Hechavarria, Brett Cecil, Trade Rumours, the Rogers Center and the Jays Spring Training record. GO JAYS GO!
Welcome to another edition of the 500 Level Podcast. Aman and Ben start off the show discussing all the big news surrounding the Leafs - the firing of Ron Wilson and the hiring of Randy Caryle as the new coach, its playoff chances and the contract extension for Mikhail Grabovski. The talk shifts to the Blue Jays with the injury to Litsch, the emergence of prospect Hechavarria and the Jays chances of securing the new wildcard berth. They then talk about the Raptors options at the NBA trade deadline, the new injury to Amir Johnson and an update on Andrea Bargnani, and playing close games against teams above them in the standings but still coming up just short. For the first time this year they spend some time talking about Toronto FC and its biggest game in franchise history against defending MLS Champs - the LA Galaxy. And they talk about the poor quality of the artificial pitch the game will be played on at the Rogers Centre. In the Around the World segment they talk about the somewhat unexpected and impending decision of Peyton Manning being released from the Colts and Rory McIlroy's rise to being the number one ranked golfer in the world and Tiger Wood's great play in the final round on the weekend. So relax, sit back, and enjoy another great episode!