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Jordana Gamble (former Canada Border Services Agency handler, Food/Plant/Animal canine handler) reveals the world of biosecurity and agricultural detection dogs—the discipline that gets zero love but produces the most finds. Working at Toronto Pearson Airport and international postal facilities, Jordana discusses the challenges, the rivalry with drug dog handlers, and why this is actually the BEST detection dog career.What We Cover:The path to becoming an ag/biosecurity handler: CBSA selection, 10-week academy, dog pairingDrug dog dropouts make excellent ag dogs (motivation differences: food vs. toys)Postal mode detection: endless boxes, short searches, keeping dogs engaged all dayPassenger mode detection: baggage carousels, fluid environment, longer search timesTraining aids: grocery store meat, smoked products, cured items, real food variationThe generalization nightmare: raw vs. cured vs. smoked meats confuse dogsFalse positives: baked goods with apple filling (legal but dog alerts)Real finds: grass cutters, dried monkeys, Iberian ham, endangered species, live animal smugglingThe rivalry: "Apple Dogs" vs. "Sausage Police" vs. Drug HandlersThreat response: African swine flu prevention, bird flu concerns, economic protectionDaily find rates: 10+ interceptions per day (vs. drug handlers going weeks with nothing)Reading your dog after thousands of finds: knowing fish smell vs. rotten ham vs. pork flossFinal response problems: dogs going active on bags (markers saved training)The "dog brain" override: when smell/frustration overrides trained behaviorWhy postal is physically brutal but rewardingHandler advice: never turn down an ag dog positionCareer satisfaction: dogs see work as playground, not just trainingWhy agricultural detection protects economies and industriesThe hidden importance of biosecurity workJordana worked both postal (conveyor lines, thousands of parcels) and passenger (airport baggage) modes. She shares how target-rich environments accelerate handler development—you get hundreds of finds to learn from, versus drug dogs going weeks without positive reinforcement. She also discusses the competitive dynamic with her drug handler husband, who now wishes he had her find rate.Critical Takeaway: "Detection work is detection work. Whether you're looking for drugs, firearms, currency, or food—it's all the same. Don't be too proud for the ag dog."________________________________________
In this episode, Ray Cochrane digs into Anthropic’s Model Hardware Standard. It is a shared driver that lets an AI agent run real lab equipment, from pipetting robots to the lasers inside a quantum computer. He also covers OpenAI’s builder’s guide to GPT-5.6, Google’s new Expert Intelligence book feature, Apple’s M5 Ultra Mac Studio, and a judge’s order forcing Google to stop hiding rival app stores. Finally, he weighs in on Apple’s proposed 15 percent link-out fee, Meta’s Australia numbers, the White House deputizing private hackers, and why rivers obey a 1957 math rule. – Want to start a podcast? Its easy to get started! Sign-up at Blubrry – Thinking of buying a Starlink? Use my link to support the show. Subscribe to the Newsletter. Email Ray if you want to get in touch! Like and Follow Geek News Central’s Facebook Page. Support my Show Sponsor: Best Godaddy Promo Codes Get 1Password Full Summary Cochrane opens with a quick personal update. He is hunting for tickets to Michigan for his dad’s anniversary, and he has been learning Blender and Godot on the side, mostly modeling and blocking out levels. Consequently, he asks listeners for advice on starting a big game project, and he plans to record his progress, maybe as a time lapse. Then it is straight into the featured story. Anthropic’s Model Hardware Standard: A Driver for the Physical World The featured story comes from Anthropic, which opened a research preview of the Model Hardware Standard, or MHS. Cochrane frames it as the other side of the question NVIDIA’s world models raised two weeks ago: when do AI agents start touching actual machines? A typical lab runs a microscope, a liquid handler, a robotic arm, and a plate reader, each from a different vendor with its own control software. One Janelia researcher in the post launches seven programs in three languages just to start an experiment. Anthropic says wiring a setup like that takes weeks or months of specialist work. MHS is a driver, the same kind of translation layer a printer uses, except every device gets described with a tiny set of commands like read and write. Devices announce themselves on the network. A plain-English reference file then records what each machine measures, what can be adjusted, and which safety limits get enforced no matter what the agent asks. Agents then reach the hardware through the Model Context Protocol, the command line, or plain code. Cochrane sees the same move the industry keeps making, from coding harnesses to RSS and JSON: agree on a standard and let everyone build against it. In fact, he calls MHS the hardware version of MCP. The partner results carry the segment. QuEra builds quantum computers from individual atoms held by lasers that must hold their frequency to about one part in a trillion. A four-person team spent months on a relock script that worked 58 percent of the time. However, four copies of Claude iterating overnight through MHS produced a decision-tree script that recovers the laser in about six seconds, and it passed 99.3 percent of 700 blind trials. Carnegie Mellon wrote MHS drivers for four instruments across three incompatible computers in about eight hours, then ran dose-response experiments three times faster and blocked all six deliberately induced faults. Genentech, meanwhile, showed the limits. Claude used the same pump speed for water, a foamy protein solution, and a human had to explain that the bubbles were a physics problem. That gap in physical intuition is what sticks with Cochrane. He doubts it will change soon, and he suspects the fix will arrive as sub-agents or sub-models that judge a request against an expected outcome. He also connects MHS to a video of racing robots that never learned to stop at the finish line. What happens, he wonders, once they can read a distance sensor through a shared standard? Still, he calls the announcement a fantastic read and points listeners to the full article. Sponsor: GoDaddy Economy hosting $6.99/month, WordPress hosting $12.99/month, domains $11.99. Website builder trial available. Use codes at geeknewscentral.com/godaddy to support the show. GPT-5.6 Does the Same Work for a Fraction of the Cost OpenAI’s builder’s guide to GPT-5.6 leads the headlines. Cochrane recaps the three tiers from episode 1870, Sol, Terra, and Luna, plus the separate dial for reasoning effort. On BrowseComp, a benchmark for digging up obscure facts on the web, the old GPT-5.5 flagship scored about 84 percent on a run that cost 33 dollars three months ago. Luna now matches that score for a dollar thirty-three, and OpenAI has since cut Luna’s price another 80 percent. Browser Use reports Luna finishing 78 percent of its hardest browser tasks for about 14 dollars, against 80 percent for roughly 235 dollars from the best available model. The guide’s other big addition is a multi-agent beta flag. It lets the model handling a request spawn parallel helper agents that report back to a root agent inside a single API call. However, Cochrane is unimpressed by the timing. He has been running that pattern in Claude Code for months, so he sees OpenAI copying a workflow other companies already ship rather than inventing its own. Along the way, he plugs Claude Code’s remote-control sessions, which let him send prompts from his phone to a terminal session at home. Google Lets Gemini Read the Books You Actually Bought Google launched Expert Intelligence, a name Cochrane calls quite the reach. The feature lets you drop a book you bought on Google Play Books into Gemini Notebook, formerly NotebookLM, and ask questions answered only from that book, with citations. Cochrane sees real power here for students, since he once used NotebookLM to organize scattered course PDFs. Additionally, publishers get a cut, which he calls a far better deal than the wholesale scraping of books that trained earlier models. Nevertheless, he asks who loses out, because a paid publisher does not automatically mean a paid author. He floats the same idea for artists, even a penny per use, then admits that may be too idealistic. Apple’s M5 Ultra Mac Studio Is Built to Run Big Models at Home Back in episode 1861, when Apple killed the Mac Pro, an M5 Ultra Mac Studio was expected later this year. Now it is here. The M5 Ultra brings up to a 36-core CPU, an 80-core GPU, and 512GB of unified memory moving 1.2 terabytes per second. Apple claims up to 4.3 times the AI performance of the M3 Ultra. Thunderbolt 5 can also cluster four machines into one memory pool for up to three times faster inference. The M5 Max model starts at $2,499 and the Ultra at $5,499, with shipping on September 22 and the 512GB configuration arriving in late October. Cochrane finds the clustering pitch ridiculous at that price, but he invites anyone who spends the money to report back. Apple Opens a Manufacturing School in Houston Apple also opened a 20,000-square-foot Advanced Manufacturing Center in Houston. It offers free classes for small and midsize manufacturers, from circuit board design to hands-on time on a scaled-down production line, with college students joining later. Cochrane calls it a solid step in the bring-manufacturing-home movement. The bigger story is the campus itself, which builds Apple’s AI servers and will add the first US-assembled Mac mini line later this year. That ties back to the Mac mini shortage that followed the OpenClaw rush, when Tim Cook warned of months-long waits. Cult of Mac was still reporting four-month waits in late July. However, Cook blamed chip supply rather than assembly, so Cochrane is not counting on relief just yet. Amazon EC2 Turns Twenty Amazon EC2 turned twenty this week, which Cochrane admits makes him feel old. The 2006 beta offered one server size in one region for ten cents an hour. Each came with a 1.7 gigahertz Xeon and under two gigabytes of memory, and accounts were capped at twenty servers. Today AWS offers more than 1,200 instance types across 39 regions. Consequently, Cochrane credits the company with turning that tiny product into the backbone of cloud and AI computing. Intel Gamer Days: Two Free Games, With Fine Print Intel Gamer Days runs through September 13. Buy a qualifying Core Ultra Series 2 or 14th Gen desktop chip, a Core Ultra Series 3 laptop, or an Arc graphics card. In return you get Star Wars: Galactic Racer plus the Tomb Raider: Legacy of Atlantis remake. GamesRadar values the pair at about 120 dollars. However, neither game is out yet, and codes must be redeemed by October 31 even though the Tomb Raider remake ships in February. Cochrane calls that awful, but he still tells qualifying buyers to claim the deal early. Note that 13th Gen chips do not qualify. Judge Orders Google to Stop Hiding Rival App Stores A jury found Google’s Android app monopoly illegal in late 2023, and Judge James Donato ordered rival stores into the Play Store in 2024. On August 13, Epic’s lawyer demonstrated that searching Play for “store for apps” returned Walmart instead of any app store. Donato called that “not acceptable” and ordered three fixes within a week. Searches must surface third-party stores, listings need a plain install button, and the “are you looking for” interstitial has to go. Cochrane welcomes the monopoly being chipped away, but he notes that a controlling entity still sits atop every app store. In his view, community hubs like app stores and social media need a public infrastructure layer. He suspects governments skip that investment because companies already run the services, while selling your data. Apple Wants 15 Percent of Purchases Outside Its Store The other half of the Epic saga is Apple’s proposed link-out commission. After the 2021 anti-steering injunction, Apple charged 27 percent on purchases made through external links. A judge held it in contempt last year, and the Ninth Circuit then allowed a fee limited to the cost of running the system. Judge Yvonne Gonzalez Rogers refused to wait for the Supreme Court, writing that “further delay is unwarranted.” Apple filed 15 percent for standard apps, 10 percent for subscription renewals and partner programs, and 5 percent for small businesses. It also conceded the rate would be “essentially zero” under the appeals court’s cost yardstick. Since Apple has charged nothing on link-outs since the contempt ruling, Cochrane sees this as a raise. He calls a cut on purchases made on a developer’s own website disturbing. He also recalls reading about the size of Uber’s payments to Apple, and he questions whether that kind of percentage is sustainable for companies without funding. Meta Says It Has Cut Off 750,000 Australian Kids Meta reported locking out more than 750,000 Facebook and Instagram accounts in Australia by the end of June under the country’s under-16 social media law. Over 500,000 of those were removed before the law even took effect. Detection relies mostly on AI scanning posts and bios for tells like birthday messages, plus user reports and blocks on re-registration. However, the post gives no count of mistaken removals or appeals, and the regulator’s early data shows under-16 usage falling only from about 86 to 81 percent. Meta wants a single age signal at the operating system or app store level, and Cochrane agrees completely. He connects it to the MHS idea from the top of the show: platforms need a standard flag to reference instead of guessing. The White House Deputizes Private Hackers Earlier this month the White House signed a National Security Presidential Memorandum that lets vetted private security firms run surveillance and disruption operations against overseas criminal groups. The Justice Department and Homeland Security hold the contracts and oversee the work. Firms need a proven track record, vetted staff, and a bond of at least $1 million, and must submit operating procedures within 60 days. Cochrane finds the measure aggressive in a good way and hopes it deters attacks on innocents. Still, he takes Kevin Beaumont’s warning seriously that the private security industry profits from ransomware existing. He compares it to the old Head and Shoulders myth: why solve the problem that drives your revenue? A Weather Satellite Watched the Eclipse Shadow Cross Europe Cochrane skips the readout on this one and simply sends listeners to ESA’s site. The MTG-I1 weather satellite captured the Moon’s shadow sweeping across Europe during the August 12 eclipse. Watching a shadow cross an entire continent, he says, was a first for him. Additionally, it leaves him excited about the research happening beyond the planet. Rivers, Deltas, and the Number 0.6 Quanta Magazine explains Hack’s law, which John Hack discovered in 1957 while measuring streams in Virginia and Maryland. A stream’s length tracks its drainage area raised to the power of 0.6, regardless of the rock underneath, and satellite data later confirmed it worldwide. Computer models in the 1990s showed why. Channels that capture extra runoff cut deeper and steal from their neighbors until the network settles into the arrangement that wastes the least energy. Now a University of Texas Rio Grande Valley team has found the same 0.6 exponent in river deltas, which spread water out rather than gathering it. Nobody knows why yet, and Cochrane calls it a really cool read. Sugar Helped Grow the Human Brain, Too A new paper in Science, co-authored by Jennie Brand-Miller at the University of Sydney, adds a third ingredient to the story of early human brain growth. Alongside meat and cooking, natural sugars from ripe fruit and honey may have fueled it too. The brain is about two percent of body weight but burns twenty percent of resting energy. It runs on glucose, which meat and marrow barely supply and raw starch cannot release without fire. The team modeled ancestral diets from a chimp-like baseline through Homo erectus and concluded that the earliest hominins may have drawn over 65 percent of their energy from natural sugars. Cochrane stresses that it is a model, not fossils, and notes that paleoanthropologist Marina Lozano thinks the authors place widespread cooking too early. Still, he loves this kind of deep research. Retracing the steps to our own intelligence, he suggests, could hint at what it takes for intelligent life to develop at all. A Brain Rhythm That Tells Doctors Where to Aim Finally, Science Daily covered a University of Cologne study on deep brain stimulation. That is the implanted-electrode treatment that eases Parkinson’s tremors for some patients but not others. Andreas Horn’s team recorded from 50 patients using both the implanted electrodes and an external magnetic scanner. They identified a circuit between the electrode’s target and the frontal cortex that oscillates at 20 to 35 cycles per second. Stronger coupling there predicted bigger improvement after surgery, though the study, published in Brain, shows correlation rather than cause. First author Bahne Bahners hopes the finding helps tune DBS more precisely, especially for patients who have not responded well. Cochrane half-jokingly asks whether MHS might one day drive those electrodes, and he calls brain disorders the hardest thing in the body to treat. Cochrane wraps with housekeeping: become a GNC Insider at geeknewscentral.com/insider, email geeknews@gmail.com with questions or comments, subscribe to the newsletter, and grab a modern podcast app at podcastapps.com. He thanks GoDaddy for over twenty years of keeping the show on the air, promises to catch everyone next Monday, and wishes listeners a great night. The post Eyes, Hands, and a Sense of Timing #1874 appeared first on Geek News Central.
In this episode, hosts Frank La Vigne and Andy Leonard sit down with Lawrence Snapp, CEO and board member of TrustScale, an innovative AI trust and verification platform. Together, they explore the crucial topic of trust in artificial intelligence—how hallucinations from AI models can spiral out of control and why it's essential to catch them early. Lawrence Snapp pulls back the curtain on TrustScale's journey from early AI and translation work in the 1980s and call center solutions, to its modern-day mission: empowering humans to verify and trust AI outputs with products like Argus. You'll hear about real-world impacts in fields like healthcare, legal, and research, learn how TrustScale's deterministic engine outpaces humans in hallucination detection, and dive into debates around truth, trustworthiness, and the future of configuring AI values. Whether you're an industry veteran or just curious about how we build trustworthy AI, this episode is packed with insights on technology, responsibility, and the power of rigorous engineering.LinksWatch on YouTube -https://www.youtube.com/watch?v=RjM7lxn3Qk8Lawrence on LinkedIn -https://www.linkedin.com/in/lawrence-snapp-408339/Time Stamps00:00 Funny AI-generated story03:37 Company's Evolution from Translation to AI07:32 Developing the TrustScale engine11:35 Using AI for collaboration13:39 Building a trust scoring system18:12 Working at BASF and AI testing19:32 New developments in voice assistants23:41 Trust scale and company confidence26:13 AI mishap in medical drama32:48 Overcoming AI recency and cost challenges36:54 AI's impact on career growth38:50 Interviewing and developing talent43:31 Starting with Polaroids and AI goals46:54 Discussing TrustScale and AI interactions50:42 Empowering AI customization for users51:45 AI ethics discussion in Los Altos
Transparency around your AI workflow and protecting your creative voice with Jeremy Carrasco from Jeremy Finds AI. ----- Welcome to episode 585 of The Food Blogger Pro Podcast! This week on the podcast, Bjork interviews Jeremy Carrasco, the creator behind Jeremy Finds AI and founder of Riddance. Why Trust Matters More Than Detection in the Age of AI with Jeremy Carrasco Pop quiz! Can you actually spot AI-generated content if you saw it? Jeremy's background in live streaming, encoding, and video production gave him an early edge in identifying synthetic content, but as AI videos get more realistic, he explains why that edge is disappearing fast, and why the old advice to simply "train your eye" isn't enough anymore. In this episode, Jeremy makes the case that the real question isn't "can you spot AI?" but "do you trust the source?" He and Bjork get into the difference between acceptable and deceptive AI use, why disclosing your AI workflow might actually build more trust with your audience, and what "human-forward" creation looks like in an increasingly synthetic feed. Jeremy also shares candidly how he uses AI in his own work, and why he refuses to let it touch his creative edge. If you create content in any capacity, this conversation gives you a clear-eyed look at where trust is headed next and what it'll take to hold onto yours. Three episode takeaways: Spotting AI is basically a coin flip now: The days of "train your eye to catch AI" are over — content's gotten too realistic, and platform algorithms make it even trickier to know what's real. Trust in the source matters way more than trying to detect fakes. There's a real difference between using AI and hiding AI: Being upfront about your AI workflow can actually build more trust with your audience, not less. It's not about ditching the tools — it's about being honest when you use them. The smartest move right now is doubling down on being human: As AI gets faster and cheaper, the creators who protect their creative voice and stay unmistakably them are the ones who'll stand out in an increasingly synthetic feed. Resources: Jeremy Finds AI Riddance Lion's Den YouTube channel: RocketJump Zach King's YouTube channel YouTube star Hank Green apologizes for ChatGPT overuse after fans accuse him of including a prompt by mistake — Fortune Patreon Substack YouTube short from Jeremy Finds AI: This political influencer isn't real Why Nobody Can Stop AI Art Scams — Jeremy Finds AI on YouTube Join the Food Blogger Pro Podcast Facebook Group Thank you to our sponsors! This episode is sponsored by Yoast and Clariti. Learn more about our sponsors at foodbloggerpro.com/sponsors. Interested in working with us too? Learn more about our sponsorship opportunities and how to get started here. If you have any comments, questions, or suggestions for interviews, be sure to email them to podcast@foodbloggerpro.com. Learn more about joining the Food Blogger Pro community at foodbloggerpro.com/membership.
All links and images can be found on CISO Series Check out this post from Caleb Sima of Whiterabbit for the discussion that is the basis of our conversation on this week's episode co-hosted David Spark, the producer of CISO Series, and Yaron Levi, CISO, Dolby. Joining is Adrian Ludwig, CSO, Rippling. In this episode: The messy middle The automatable part Where automation stops The influence gap A huge thanks to our sponsor, ThreatLocker ThreatLocker delivers Zero Trust Network Access and Zero Trust Cloud Access that verifies both user and device before granting access to specific applications. No broad access, nothing exposed, and no reliance on credentials alone. It's a smarter way to control access and reduce risk. Learn more at ThreatLocker.com/CISO.
Dave Asprey and Gabby Reece Talk Testosterone Therapy, Scream Cream, Autism as a Superpower, Cancer Protocols, and Surviving Fame in This Double Interview Episode Mega-Episode time! Your hormones might be causing symptoms you've been blaming on aging, stress, or your heart. This double interview episode gives you a real look at biohacking from two different angles: cutting-edge longevity science and the lived experience of hormone optimization after 50. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Gabby Reece, an American athletic icon, wellness entrepreneur, and one of the most influential voices in women's health, fitness, and performance. A former professional beach volleyball player who became Nike's first female spokesperson and shoe designer, Gabby set volleyball records at Florida State University that still stand today, and her signature Nike shoe line famously outsold Air Jordan during its release. She has since built a career at the intersection of performance and longevity, co-founding Hamilton House, Laird Superfood (NYSE: LSF), XPT, and HIGHX, and hosting both The Gabby Reece Show and the Proof of Practice podcast alongside leading voices in women's health and evidence-based performance. She is also a New York Times bestselling author. In this episode, Gabby turns the tables and interviews Dave herself, creating a rare two-way conversation between two people deeply immersed in human performance and biohacking. Dave and Gabby dig into how mitochondria function as quantum systems that shape everything from cognitive performance to spiritual perception, why autism can come with genuine neurological superpowers, and what actually happens in the body when hormone levels shift after 40. Gabby shares her personal protocol, including weekly testosterone injections, an estradiol patch, and a compounded hormone cream that most people have never heard of, and explains how correcting her hormones, not her thyroid, resolved a heart arrhythmia doctors initially missed. The conversation also covers Dave's approach to cancer protocols, why he avoids GLP-1 drugs despite their longevity benefits, the peptides he actually uses for mitochondrial renewal, and how cyclical ketosis, fasting, and a carnivore-leaning diet fit into a sustainable performance strategy. They also talk about AI's growing role in personalized longevity research, sleep optimization while traveling, and the supplement and functional medicine protocols Dave relies on daily. You'll Learn: Why Gabby's heart arrhythmia turned out to be a hormone problem, not a cardiac one, and how testosterone fixed it when nothing else worked What "scream cream" actually is, how it works through vasodilation, and why doctors quietly prescribe it during hormone replacement therapy How mitochondria function as quantum systems and why improving their function can sharpen intuition, focus, and perception Why Dave believes autism comes paired with real cognitive advantages once the physical burden of the condition is addressed What Dave would actually do if diagnosed with cancer, from antifungal protocols to high-power infrared light and early detection screening The peptides Dave uses for mitochondrial renewal, including SS31 and lesser-known Russian bioregulators like epitalon and pinealon Why Dave avoids GLP-1 drugs despite believing low doses carry real longevity benefits How cyclical ketosis, fasting windows, and a carnivore-leaning diet support sustainable long-term metabolism Why surrender, not control, was the hardest and most expensive lesson of Dave's career Gabby's advice for raising confident daughters and why she believes success is less about deserving it and more about how you steward it Thank you to our sponsors! - Beyond Wonderland Conference | Oct 13 - 14, 2026. Get your ticket now at wonderlandconference.com. - Visit www.myvitalc.com/davesfav to unlock Dave's discount - Fatty15 | You can get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com DAVE and using code DAVE at checkout - Omni-Biotic | Discover your formula at OmnibioticLife.com. Take 20% off your first order with code ASPREY. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights inhealth, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: testosterone therapy, hormone replacement therapy, HRT for women, weekly testosterone injections, scream cream, compounded testosterone cream, vasodilation, AFib hormones, heart arrhythmia, menopause symptoms, thyroid vs testosterone, mitochondria quantum biology, biohacking, Dave Asprey, autism superpowers, cancer protocols, serrapeptase, nattokinase, peptides longevity, cyclical ketosis, carnivore diet, Gabby Reece, longevity for women, anti-aging hormones Resources: • Learn More About The Hamilton House At: https://hamiltonhouse.co/ • Watch Gabby's Podcast At: https://www.youtube.com/@GabbyReece • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15? • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 00:00 – Trailer 00:52 – Gabby Interviews Dave 02:58 – Fatherhood and Teenagers 12:25 – Autism and Superpowers 17:02 – Quantum Biology & Biohacking 24:03 – Autism Epidemic and Hope 35:01 – Joe Rogan Feud 48:04 – Death, Immortality, Living to 180 56:24 – The Four F's Framework 1:04:55 – Cancer Prevention and Detection 1:18:20 – Travel Biohacking Tips 1:31:46 – Nothing You Can't Hack 1:41:23 – Peptides Deep Dive 1:52:33 – The Human Upgrade Podcast Starts 1:59:35 – Advice at Eighteen 2:10:03 – Fame and Holding Back 2:22:44 – Hormone Replacement Therapy 2:31:31 – Pursuit Over Happiness 2:43:02 – Advice for Tall Women See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Qualys returns to Black Hat USA 2026 with an AI Risk Operations Center built around three principles customers have been asking for over the last three years. May Mitchell, Chief Marketing Officer at Qualys, walks through them in order. Detect vulnerabilities at AI speed. Prioritize what surfaces, because not every finding calls for action in the same hour and the sequence follows the workflows a team already runs. Eliminate it through autonomous remediation, then confirm the fix worked. Mitchell also notes that Qualys has been a Black Hat sponsor for over 23 years. What are security teams asking for at AI speed? They want detection to keep pace with disclosure. Mitchell points to InstaScan, the innovation Qualys launched during Black Hat week, which provides continuous scanning and detection. The meetings on the floor have been with customers from across the regions, not only the US. How has the AI conversation shifted since RSAC Conference? It has narrowed to implementation. Mitchell says the messaging moved from AI to agents to autonomous, and that this year the questions are targeted. How do I implement it. How do I get it into the workflows. How do I have governance. The economics of AI sits alongside those questions, with more asked about ROI, since budgets are not rising across the board. That pushes organizations to evaluate their technology stack, consolidate, and look for a single platform that gives complete visibility and gives security leaders something they can take to a board or a CFO. Customization depends on the size of the organization, and larger heterogeneous environments are where Qualys partners come in with risk assessment services, planning, integration, and ongoing management. This is a Brand Briefing. A Brand Briefing is an on-location conversation recorded on site at Black Hat USA 2026, putting a spotlight on the guest and their company and pairing it with the editorial reach of ITSPmagazine. Learn more: https://www.studioc60.com/performance/#briefing GUEST May Mitchell, Chief Marketing Officer at Qualys On LinkedIn: https://www.linkedin.com/in/maymitchell/ RESOURCES Black Hat USA 2026 event coverage: https://www.itspmagazine.com/black-hat-usa-2026-cybersecurity-event-coverage-in-las-vegas Qualys: https://www.qualys.com/ InstaScan announcement: https://www.qualys.com/company/newsroom/news-releases/usa/qualys-launches-instascan-to-detect-vulnerabilities-within-minutes-of-disclosure Agent Insta and scanless detection: https://blog.qualys.com/product-tech/2026/08/03/instascan-agent-insta-scanless-detection ROCon Americas 2026 in Austin: https://www.qualys.com/rocon/2026/americas Are you interested in telling your story? ▶︎ Full Length Brand Story: https://www.studioc60.com/content-creation#full ▶︎ Brand Spotlight Story: https://www.studioc60.com/content-creation#spotlight ▶︎ Brand Highlight Story: https://www.studioc60.com/content-creation#highlight ▶︎ Get your own Brand Briefing at an upcoming event: https://www.studioc60.com/buy-brand-briefings KEYWORDS May Mitchell, Qualys, Marco Ciappelli, brand briefing, brand story, brand marketing, marketing podcast, Black Hat USA 2026, risk operations center, InstaScan, AI speed detection, autonomous remediation, vulnerability management, prioritization, security governance, economics of AI, platform consolidation, cyber risk management, CISO, ROCon Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
Why Watermark?Claude wants everybody to know it is there. Keith Teare argues that this is exactly the wrong instinct. The issue is not whether AI touched a piece of work. The issue is whether the work is true, useful, accountable, and human-directed.Watermarking starts from suspicionA watermark assumes there is a problem to solve. Keith's objection is that Anthropic appears to be accepting the premise that AI use tarnishes the user. If Claude helped draft, structure, summarize, or edit human-origin work, why is that the fact that must be marked? The mark answers the wrong question: not whether the work is good, true, accountable, or human-directed, but whether Claude was there.Detection tools confuse use with authorshipAndrew ran Keith's editorial through an AI detector and got an 86% AI score; Keith ran Saul Klein's article through one and got 100%. Neither result proves much. Andrew also admitted he uses Claude as a draft and then rewrites it. Keith described the same process: give AI the source material, ask it to surface themes, debate the frame, then rewrite. The question is not whether AI helped. The question is who is responsible for the final work.The shame belongs in the wrong placeKeith accepts that shame has a place: spam factories, fake authorship, unreviewed AI output, fake evidence, and publishing something you cannot stand behind. He feels no shame in "recruiting an army of AI agents" to help accomplish his goals, provided he reads, changes, edits, and owns the output. Society is trying to attach shame to the tool itself. That is the mistake.AI should be cheap and everywhereThe show turns from watermarking to access. Grok Bot at $200 a month is a sign of capability, but also a sign of scarcity. Keith argues that equality in AI is about price and reach: how cheap is it, and how widespread is it? If intelligence is valuable, the goal should be to make it free or nearly free for many use cases, not to add friction that helps the Luddite argument.Abundance requires massive investmentKeith defends the scale of AI investment because demand still exceeds supply. Nvidia's half-trillion-dollar commitment, hyperscaler deals, IPOs, and AI infrastructure financing are not just market exuberance. They are the precondition for AI to reach everyone. As Keith puts it, if you want AI in the hands of an African school child, you have to build the infrastructure first. The risk is not that too much is being built. It may be that too little is being built, or that access is captured at the price and distribution layer.Bottom line: AI is good. Build enough of it for everyone. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.thatwastheweek.com/subscribe
Recorded on location at Black Hat USA 2026 in Las Vegas at the end of day two, Karthik Kannan, Founder and CEO at Anvilogic, walks through a seven year build that reached its original shape this year. The plan from the start was a full security operations platform covering data, the detection engineering process, triage and investigation, and case management. In the shorthand of the category, SIEM and SOAR combined. It arrived in phases. Detection engineering came first, implemented on top of Splunk for most customers, then the data platform expanded into data lakes including Snowflake, Databricks, and Microsoft Azure. Triage and investigation followed over the last two years. In the last year Anvilogic rolled out agents that carry out the work of specific personas, and this year the company launched Blueprints, an orchestrator agent that brings the discrete agents together to run a whole workflow with humans in the loop. What separates a security graph from a frontier model? It knows the environment. Karthik Kannan describes the enterprise security graph as Anvilogic's own model running inside the network, learning the micro environment, with frontier LLMs called on to fill gaps in the macro environment. His argument is that platforms operating as LLM wrappers miss the last mile, because AI on its own reaches 60, 70, or 80 percent of the way if you are lucky. How does a team keep control when agents run the workflow? Through gates, permissions, and a record of what happened. Workflows can be described in plain English, with human gates inserted as often as the team wants. Access controls sit at the persona, organization, and object levels, and activity is audited and logged, which matters to the GRC teams Anvilogic works with. Screens dedicated to what the company calls a maturity score show which feeds are coming in, what kinds of detections exist, and what coverage looks like against the MITRE ATT&CK framework, in a form available to executives and CISOs. Karthik Kannan also points to version 8.0, introduced the week before the event, which includes an Anvilogic MCP Server for connecting to third party tools. Customers are already building their own Blueprint workflows during proofs of concept, including a large life sciences customer Anvilogic expects to feature in a public case study. Karthik Kannan is careful about the claim being made here. This is not a proclamation of an autonomous SOC. It is automation that makes life in a SOC easier and more efficient, adopted at a crawl, walk, run pace, with every step visible along the way. This is a Brand Briefing. A Brand Briefing is an on-location conversation recorded on site at Black Hat USA 2026, putting a spotlight on the guest and their company and pairing it with the editorial reach of ITSPmagazine. Learn more: https://www.studioc60.com/performance/#briefing GUEST Karthik Kannan, Founder and CEO at Anvilogic On LinkedIn: https://www.linkedin.com/in/karthikkannan001/ RESOURCES Black Hat USA 2026 event coverage from ITSPmagazine: https://www.itspmagazine.com/black-hat-usa-2026-cybersecurity-event-coverage-in-las-vegas Learn more about Anvilogic: https://www.anvilogic.com Anvilogic 8.0, from onboarding to investigation: https://www.anvilogic.com/learn/anvilogic-8-0-automate-the-soc Are you interested in telling your story? ▶︎ Full Length Brand Story: https://www.studioc60.com/content-creation#full ▶︎ Brand Spotlight Story: https://www.studioc60.com/content-creation#spotlight ▶︎ Brand Highlight Story: https://www.studioc60.com/content-creation#highlight ▶︎ Get your own Brand Briefing at an upcoming event: https://www.studioc60.com/buy-brand-briefings KEYWORDS karthik kannan, anvilogic, sean martin, brand briefing, brand story, brand marketing, marketing podcast, black hat usa 2026, agentic secops, ai soc platform, enterprise security graph, detection engineering, triage and investigation, blueprints orchestrator agent, mcp server, mitre att&ck coverage, human in the loop automation, siem and soar, security operations, grc audit logs Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
MedAxiom HeartTalk: Transforming Cardiovascular Care Together
In this episode of MedAxiom HeartTalk, host Melanie Lawson, MS speaks with Byron Lee, MD, professor of medicine and cardiology at Stanford, about the growing importance of remote cardiac monitoring in patient care. Dr. Lee shares how extended 30-day monitoring helps improves arrhythmia detection and guides long-term treatment. He also discusses how real-time data transmission and streamlined reporting allow care teams to identify and address serious cardiac events more quickly and confidently.
OpenAI loosens cyber limits for vetted defenders Sandworm's fake recruiters plant a poisoned VPN Royal Navy drones phone home to China Episode show notes: https://cisoseries.com/openai-loosens-cyber-limits-sandworms-poisoned-vpn-navy-drones-phone-china/ Huge thanks to our sponsor, ThreatLocker An attacker uses AI to create a payload your security tools have never seen. Detection now has to recognize it before the payload can act. ThreatLocker approaches the problem earlier by controlling whether that code is permitted to run at all. Explore a deny by default approach for your organization at threatlocker.com/ciso.
Kevin Hoy discusses the detection of a Jupiter-mass object orbiting the brown dwarf CD-35 2722b, which may represent the first confirmed exosatellite or exomoon. Using the radial velocity method, researchers identified a "wobble" in the spectrum of the brown dwarf, indicating a secondary body in a highly eccentric 170-day orbit. This discovery is a significant milestone for astrophysics, as it helps scientists understand planetary formation processes outside our solar system. Hoy explains that such objects are difficult to find because technology is often limited by the brightness and proximity of host stars. Future mapping of nearby systems could involve high-power radar technology. (2)
Mars won't get cities because it becomes easy to live there. It gets cities because people stay. We explore how the first fragile outposts become homes, economies, neighborhoods, and civilization.Get Nebula using my link for 50% off an annual subscription: https://go.nebula.tv/isaacarthurCheck out TierZoo Remastered: https://nebula.tv/tierzoo/tierzoo-remastered?ref=isaacarthurAres Inception on Steam: https://store.steampowered.com/app/4512810/Ares_Inception/
Mars won't get cities because it becomes easy to live there. It gets cities because people stay. We explore how the first fragile outposts become homes, economies, neighborhoods, and civilization.Get Nebula using my link for 50% off an annual subscription: https://go.nebula.tv/isaacarthurCheck out TierZoo Remastered: https://nebula.tv/tierzoo/tierzoo-remastered?ref=isaacarthurAres Inception on Steam: https://store.steampowered.com/app/4512810/Ares_Inception/
In the first episode of this special three-part series, Neil Skolnik speaks with Dr. Minesh Rajpal. Together, they provide an overview, discussing the assessment and management of high blood pressure. This special episode is sponsored with support from AstraZeneca. Presented by: Neil Skolnik, MD, Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington Jefferson Health Minesh Rajpal, MD, Attending Nephrologist and Hypertension Specialist at the Southwest Kidney Institute References: 2025 AHA/ACC/AANP/AAPA/ABC/ACCP/ACPM/AGS/AMA/ASPC/NMA/PCNA/SGIM Guideline for the Prevention, Detection, Evaluation and Management of High Blood Pressure in Adults: A Report of the American College of Cardiology/American Heart Association Joint Committee. Hypertension 2025; 82(10) Blood pressure lowering for prevention of cardiovascular disease and death: a systematic review and meta-analysis. Lancet 2016;387:957
The 2000s launched some of the most influential fantasy, science-fiction, and horror authors of the modern era—but which debut novels have truly stood the test of time?In this episode of Fantasy for the Ages, Jim selects one fantasy debut, one science-fiction debut, and one horror debut for every year from 2000 through 2009—thirty winning novels in all.Every selection follows one strict rule: the book must be the author's first complete novel ever made publicly available, including earlier self-published or online releases. Original worldwide publication dates also govern, rather than later American editions.Which winners did Jim get exactly right? Which runner-up deserved the top position? And what overlooked fantasy, science-fiction, or horror debut from the 2000s belongs in the conversation?If you enjoy fantasy, science fiction, horror, rankings, deep dives, and reading recommendations, please like the video and subscribe to Fantasy for the Ages.#FantasyBooks #ScienceFiction #HorrorBooks #BookTube #DebutNovels #FantasyForTheAges #ReadingRecommendations #HouseOfLeaves #JonathanStrangeAndMrNorrell #TheBladeItself #TheNameOfTheWind #TheWindupGirl⸻Want to purchase books/media mentioned in this episode?Agent to the Stars: t.ly/XqAc6Altered Carbon: t.ly/Cb2jkArchangel Protocol: t.ly/h8wHmThe Atrocity Archives: t.ly/Gkr9_The Blade Itself: https://t.ly/LSDn2Breathers: A Zombie's Lament: t.ly/9fYw4City of Bones: t.ly/UPuBuCity of Pearl: t.ly/7NlL-Counting Heads: t.ly/MNnOtCovenant: t.ly/pBl9CThe Coyote Kings of the Space-Age Bachelor Pad: t.ly/dfc_zCrystal Rain: t.ly/08sZ_Damnable: t.ly/qgmlcThe Darkness That Comes: https://t.ly/aDLrIDeadliest of the Species: t.ly/Mh1evEragon: https://t.ly/nxt-RThe Etched City: t.ly/t1ehRThe Eyre Affair: t.ly/xfhlAThe Gentling Box: t.ly/XTg1wGhost Road Blues: t.ly/34qfjThe Ghost Sister: t.ly/s5MonThe Gone-Away World: t.ly/1braxGraceling: t.ly/INRDoHammered: t.ly/v4gE3Harbinger: t.ly/pz75VHeart-Shaped Box: https://t.ly/XBPTiHis Majesty's Dragon: https://t.ly/BrOkWThe Historian: t.ly/Ji8lxHouse of Leaves: https://t.ly/H1z_WJonathan Strange & Mr Norrell: https://t.ly/8MoJBThe Keeper: t.ly/pPrC-The King's Peace: t.ly/TuSKVKushiel's Dart: https://t.ly/28SIoThe Licking Valley Coon Hunters Club: t.ly/cRCwKThe Lies of Locke Lamora: https://t.ly/1UV3hThe Lovely Bones: t.ly/YDUBHThe Manual of Detection: t.ly/s9uRVMars Crossing: t.ly/5Z5ijMove Under Ground: t.ly/qzKAsThe Name of the Wind: https://t.ly/ndJbgOld Man's War: t.ly/Q_CogOne for Sorrow: t.ly/lJJoMOne Jump Ahead: t.ly/BKJWeThe Painted Man: t.ly/QoSG6Pandemonium: t.ly/l9yFlPlague Year: https://t.ly/fj7QEThe Red Church: t.ly/JYnKJRevelation Space: t.ly/1GyXCThe Rising: t.ly/2hRB3Riverwatch: t.ly/pGZhgScarecrow Gods: t.ly/9fHjiA Scattering of Jades: t.ly/hX7rqSingularity's Ring: t.ly/PeF15Soulless: t.ly/2wX3bSpin State: t.ly/q2SymThe Suicide Collectors: t.ly/ezklGSummer of the Apocalypse: t.ly/wE0zjThe Time Traveler's Wife: t.ly/SJIfyTransformation: t.ly/MoqvgTwilight: t.ly/yMEi-Vellum: https://t.ly/welYgVeniss Underground: t.ly/TN31qThe Windup Girl: t.ly/nBoh1The Year of Our War: t.ly/E1FqMWays to connect with us:Follow Jim/Father on Goodreads: https://www.goodreads.com/user/show/13848336-jim-scriven Join us on Discord: https://discord.gg/jMWyVJ6qKk Follow us on "X": @Fantasy4theAges Follow us on Blue Sky: @fantasy4theages.bsky.socialFollow us on Instagram: fantasy_for_the_ages Follow us on Mastodon: @FantasyForTheAges@nerdculture.de Email us: FantasyForTheAges@gmail.com Check out our merch: https://www.newcreationsbyjen.com/collections/fantasyfortheagesJim's Microphone: Blue Yeti https://tinyurl.com/3shpvhb4 Jim's Camera: Razer Kito Pro https://tinyurl.com/c873tc2n 0:00 - Opening 1:52 - Episode Explanation3:35 - Best Debuts of the 2000s39:21 - What the 2000s Changed41:48 - Jim's Personal Picks43:31 - Wrap-up & Conclusion
Alzheimer's disease can begin developing years before memory and thinking problems become noticeable. Iris Broce-Diaz, Ph.D., of UC San Diego is developing accessible, noninvasive, and cost-effective tools to help primary care physicians and neurologists identify people at higher risk earlier. Her models combine information from cognitive assessments, brain imaging, genetics, and PET scans to estimate the likelihood that mild cognitive impairment will progress within five years. Combining multiple measures improves the models' ability to separate higher- and lower-risk patients. Broce-Diaz also plans to add women-specific factors, including menopause history, hormone therapy, reproductive history, endocrine markers, and symptoms. The goal is to support better referrals, guide monitoring, and help eligible patients consider treatment sooner. Earlier risk assessment could also strengthen clinical trials and make dementia care more useful across different health systems. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 41632]
Alzheimer's disease can begin developing years before memory and thinking problems become noticeable. Iris Broce-Diaz, Ph.D., of UC San Diego is developing accessible, noninvasive, and cost-effective tools to help primary care physicians and neurologists identify people at higher risk earlier. Her models combine information from cognitive assessments, brain imaging, genetics, and PET scans to estimate the likelihood that mild cognitive impairment will progress within five years. Combining multiple measures improves the models' ability to separate higher- and lower-risk patients. Broce-Diaz also plans to add women-specific factors, including menopause history, hormone therapy, reproductive history, endocrine markers, and symptoms. The goal is to support better referrals, guide monitoring, and help eligible patients consider treatment sooner. Earlier risk assessment could also strengthen clinical trials and make dementia care more useful across different health systems. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 41632]
Alzheimer's disease can begin developing years before memory and thinking problems become noticeable. Iris Broce-Diaz, Ph.D., of UC San Diego is developing accessible, noninvasive, and cost-effective tools to help primary care physicians and neurologists identify people at higher risk earlier. Her models combine information from cognitive assessments, brain imaging, genetics, and PET scans to estimate the likelihood that mild cognitive impairment will progress within five years. Combining multiple measures improves the models' ability to separate higher- and lower-risk patients. Broce-Diaz also plans to add women-specific factors, including menopause history, hormone therapy, reproductive history, endocrine markers, and symptoms. The goal is to support better referrals, guide monitoring, and help eligible patients consider treatment sooner. Earlier risk assessment could also strengthen clinical trials and make dementia care more useful across different health systems. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 41632]
Alzheimer's disease can begin developing years before memory and thinking problems become noticeable. Iris Broce-Diaz, Ph.D., of UC San Diego is developing accessible, noninvasive, and cost-effective tools to help primary care physicians and neurologists identify people at higher risk earlier. Her models combine information from cognitive assessments, brain imaging, genetics, and PET scans to estimate the likelihood that mild cognitive impairment will progress within five years. Combining multiple measures improves the models' ability to separate higher- and lower-risk patients. Broce-Diaz also plans to add women-specific factors, including menopause history, hormone therapy, reproductive history, endocrine markers, and symptoms. The goal is to support better referrals, guide monitoring, and help eligible patients consider treatment sooner. Earlier risk assessment could also strengthen clinical trials and make dementia care more useful across different health systems. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 41632]
Alzheimer's disease can begin developing years before memory and thinking problems become noticeable. Iris Broce-Diaz, Ph.D., of UC San Diego is developing accessible, noninvasive, and cost-effective tools to help primary care physicians and neurologists identify people at higher risk earlier. Her models combine information from cognitive assessments, brain imaging, genetics, and PET scans to estimate the likelihood that mild cognitive impairment will progress within five years. Combining multiple measures improves the models' ability to separate higher- and lower-risk patients. Broce-Diaz also plans to add women-specific factors, including menopause history, hormone therapy, reproductive history, endocrine markers, and symptoms. The goal is to support better referrals, guide monitoring, and help eligible patients consider treatment sooner. Earlier risk assessment could also strengthen clinical trials and make dementia care more useful across different health systems. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 41632]
Alzheimer's disease can begin developing years before memory and thinking problems become noticeable. Iris Broce-Diaz, Ph.D., of UC San Diego is developing accessible, noninvasive, and cost-effective tools to help primary care physicians and neurologists identify people at higher risk earlier. Her models combine information from cognitive assessments, brain imaging, genetics, and PET scans to estimate the likelihood that mild cognitive impairment will progress within five years. Combining multiple measures improves the models' ability to separate higher- and lower-risk patients. Broce-Diaz also plans to add women-specific factors, including menopause history, hormone therapy, reproductive history, endocrine markers, and symptoms. The goal is to support better referrals, guide monitoring, and help eligible patients consider treatment sooner. Earlier risk assessment could also strengthen clinical trials and make dementia care more useful across different health systems. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 41632]
Screens are often unavoidable but that doesn't mean your eyes and brain have to stay overwhelmed all day.In this episode of Migraine Heroes Podcast, host Diane Ducarme shares nine realistic ways to make computers, phones, and tablets easier on a migraine-sensitive nervous system—without giving up work, communication, or productivity.You'll learn:
When license plate readers become stalking tools ExfilSquad dumps UK police contact data China-linked hackers shrink the patch window Get the show notes here: https://cisoseries.com/cybersecurity-news-license-plate-readers-as-stalking-tools-exfilsquad-dumps-uk-police-data-the-ever-shrinking-patch-window/ Huge thanks to our episode sponsor, ThreatLocker An attacker uses AI to create a payload your security tools have never seen. Detection now has to recognize it before the payload can act. ThreatLocker approaches the problem earlier by controlling whether that code is permitted to run at all. Explore a deny by default approach for your organization at threatlocker.com/ciso.
PeerView Family Medicine & General Practice CME/CNE/CPE Video Podcast
This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/CPE/AAPA/ASWB-ACE/CDR/APA/IPCE information, and to apply for credit, please visit us at PeerView.com/AXC865. CME/MOC/NCPD/CPE/AAPA/ASWB-ACE/CDR/APA/IPCE credit will be available until July 23, 2027.Connecting Minds to Support Cognitive Health and Early Alzheimer's Disease: Refining Skills and Workflows for Prevention, Detection, and Diagnosis In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Lilly.Disclosure information is available at the beginning of the video presentation.
This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/CPE/AAPA/ASWB-ACE/CDR/APA/IPCE information, and to apply for credit, please visit us at PeerView.com/AXC865. CME/MOC/NCPD/CPE/AAPA/ASWB-ACE/CDR/APA/IPCE credit will be available until July 23, 2027.Connecting Minds to Support Cognitive Health and Early Alzheimer's Disease: Refining Skills and Workflows for Prevention, Detection, and Diagnosis In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Lilly.Disclosure information is available at the beginning of the video presentation.
PeerView Neuroscience & Psychiatry CME/CNE/CPE Audio Podcast
This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/CPE/AAPA/ASWB-ACE/CDR/APA/IPCE information, and to apply for credit, please visit us at PeerView.com/AXC865. CME/MOC/NCPD/CPE/AAPA/ASWB-ACE/CDR/APA/IPCE credit will be available until July 23, 2027.Connecting Minds to Support Cognitive Health and Early Alzheimer's Disease: Refining Skills and Workflows for Prevention, Detection, and Diagnosis In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Lilly.Disclosure information is available at the beginning of the video presentation.
This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/CPE/AAPA/ASWB-ACE/CDR/APA/IPCE information, and to apply for credit, please visit us at PeerView.com/AXC865. CME/MOC/NCPD/CPE/AAPA/ASWB-ACE/CDR/APA/IPCE credit will be available until July 23, 2027.Connecting Minds to Support Cognitive Health and Early Alzheimer's Disease: Refining Skills and Workflows for Prevention, Detection, and Diagnosis In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Lilly.Disclosure information is available at the beginning of the video presentation.
PeerView Neuroscience & Psychiatry CME/CNE/CPE Video Podcast
This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/CPE/AAPA/ASWB-ACE/CDR/APA/IPCE information, and to apply for credit, please visit us at PeerView.com/AXC865. CME/MOC/NCPD/CPE/AAPA/ASWB-ACE/CDR/APA/IPCE credit will be available until July 23, 2027.Connecting Minds to Support Cognitive Health and Early Alzheimer's Disease: Refining Skills and Workflows for Prevention, Detection, and Diagnosis In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Lilly.Disclosure information is available at the beginning of the video presentation.
This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/CPE/AAPA/ASWB-ACE/CDR/APA/IPCE information, and to apply for credit, please visit us at PeerView.com/AXC865. CME/MOC/NCPD/CPE/AAPA/ASWB-ACE/CDR/APA/IPCE credit will be available until July 23, 2027.Connecting Minds to Support Cognitive Health and Early Alzheimer's Disease: Refining Skills and Workflows for Prevention, Detection, and Diagnosis In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Lilly.Disclosure information is available at the beginning of the video presentation.
PeerView Family Medicine & General Practice CME/CNE/CPE Audio Podcast
This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/CPE/AAPA/ASWB-ACE/CDR/APA/IPCE information, and to apply for credit, please visit us at PeerView.com/AXC865. CME/MOC/NCPD/CPE/AAPA/ASWB-ACE/CDR/APA/IPCE credit will be available until July 23, 2027.Connecting Minds to Support Cognitive Health and Early Alzheimer's Disease: Refining Skills and Workflows for Prevention, Detection, and Diagnosis In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Lilly.Disclosure information is available at the beginning of the video presentation.
Alan interviews Cole Rosentreter. Canadian Cole Rosentreter's company, FlyPegasus.ai, provides real-time icing detection systems applied directly to aircraft surfaces. MIDAS technology shows where ice is forming, how thick it is, and how fast it is building, so pilots can accurately assess risk. Make sure to subscribe to the podcast at Apple Podcasts, or wherever you get your podcasts. Website: www.FlyPegasus.ai
Could life survive in oceans that eat glass and treat water as poison? Explore fluorine-rich biology, hydrogen fluoride seas, and alien creatures whose metabolisms resemble carefully contained rocket engines.Get Nebula using my link for 50% off an annual subscription: https://go.nebula.tv/isaacarthurCheck out TierZoo Remastered: https://nebula.tv/tierzoo/tierzoo-remastered?ref=isaacarthur
Could life survive in oceans that eat glass and treat water as poison? Explore fluorine-rich biology, hydrogen fluoride seas, and alien creatures whose metabolisms resemble carefully contained rocket engines.Get Nebula using my link for 50% off an annual subscription: https://go.nebula.tv/isaacarthurCheck out TierZoo Remastered: https://nebula.tv/tierzoo/tierzoo-remastered?ref=isaacarthur
Tonight on America At Night with McGraw Milhaven, David Katz, founder and principal of Katz & Associates, breaks down the political standoff surrounding Todd Blanche's nomination, examining the latest developments on Capitol Hill and what the outcome could mean for the administration and the Senate. Then, Dr. Michael Benatar, Chief of the Neuromuscular Division and Vice Chair of Clinical Research at the University of Miami Miller School of Medicine, discusses promising new research exploring whether blood tests may one day help predict ALS before symptoms appear, and what these findings could mean for earlier diagnosis, treatment and the future of ALS research. Plus, editor and author Luke Barr shares the fascinating story behind his book, The Secret History of French Cooking, exploring the people, traditions and untold history that helped shape one of the world's most celebrated cuisines. And entertainment guru Mathew Wolfe returns to break down the summer box office, discussing the biggest films, surprise hits and what audiences are watching as the summer movie season continues. Learn more about your ad choices. Visit podcastchoices.com/adchoices
Jedediah Berry, author of The Manual of Detection and The Naming Song, joins us to discuss his new sword & sorcery novel Kill All Wizards. Ad-free episodes are available to our paid supporters over at patreon.com/geeks. Learn more about your ad choices. Visit megaphone.fm/adchoices
Tim Baird (Vice President, AK9I) and James Overton (Operations/Business Development, AK9I) break down exactly how to become a detection dog handler—whether you're a veteran, civilian, or career changer. They discuss training programs, the GI Bill, dog selection, breed trends, and AK9I's school safety operations that have reduced violent incidents by 87% in Virginia schools.What We Cover:How to get into canine detection (veteran and civilian pathways)Using the GI Bill to fund your K9 training (the process is "incredibly easy")AK9I's nationally accredited trade school program (6, 8, 10, 12-week courses)Qualifications: 18+ years old, high school diploma (that's it)Do you need dog experience? No. Do you need military background? No.What disqualifies personal dogs (environmental soundness is #1)Dog selection on day one (and why "pretty" doesn't win)Breed trends: why floppy ears are now in high demand for schoolsPost-graduation employment: 80% placement rate for AK9I graduatesSummer gig opportunities: $40-50/hour + travel/hotel paid (FIFA, NFL, events)Single-purpose vs. dual-purpose dogs: which for your career goals?School safety operations: explosives, firearms, narcotics detectionReal impact statistics: 47% reduction in narcotics, 87% reduction in violent incidentsDeterrence vs. detection: what schools actually needCareer earnings and lifestyle (yes, you'll spend it all on your dog)Veterans finding post-military purpose through K9 workMixed-background classes: why civilian + military handlers learn best togetherProfessionalism and social media presence (industry expectations)How to stand out in a competitive job marketFor: Veterans seeking career transitions, civilians career-changing, school administrators, law enforcement, security professionals, anyone asking "how do I become a K9 handler?"Key Takeaway: You don't need a military or law enforcement background to become a detection dog handler. You need commitment, willingness to relocate/travel, and the right mindset. AK9I has trained hundreds through their nationally accredited program with an 80% post-graduation employment rate.Tim Baird: Vice President, AK9I; former Auburn University K9 program director; decades of canine detection experienceJames Overton: 8 years Army, Operations & Business Development at AK9I; 12+ years in canine detection; school safety program founder; passionate about veteran transitionCameron Ford: Naval Special Warfare K9 trainer, Ford K9 founder, detection dog consultantAK9I Background: Founded 2001, originally trained IDD (Improvised Explosive Device) detection dogs for U.S. Marine Corps. Now nationally accredited trade school specializing in civilian and veteran K9 handler training. Operating school safety programs across Virginia school districts.
If you've been on the internet lately, you've probably been fooled by AI at least once. Don't worry, you're not alone. One poll by the data security company, All About Cookies, found that 77 percent of Americans have been duped by artificial intelligence at some point.Sometimes it can seem harmless – like that viral TikTok video of bunnies jumping on a trampoline, which raked in over 25 million likes. But AI has also been used maliciously, creating misinformation in the realm of politics, health, and breaking news events.The use of AI has also duped people within the creative fields – from music to visual art. And it's being used within education as teachers raising concerns over widespread cheating.How can detection tools keep up with all the fast-changing technology and its varied uses?Find more of our programs online. Listen to 1A sponsor-free by signing up for 1A+ at plus.npr.org/the1a.See pcm.adswizz.com for information about our collection and use of personal data for sponsorship and to manage your podcast sponsorship preferences.NPR Privacy Policy
In this episode, we examine the uncanny valley in AI's success in bug detection. We discuss the balance between automation and human oversight.Chapters00:00 Microsoft Bug Hunting AI02:01 Google's SynthID Watermark04:59 Encore AI's Voice Agents10:16 Writers Embrace Typos14:59 Sierra Acquires Oasis Security17:01 Recent Industry Headlines Show LinksGet the top 80+ AI Models for $8.99 at AI Box: https://aibox.aiHow I Grow and Scale My Business with AI: https://www.skool.com/aihustleGet the AI Chat Daily Newsletter: https://www.aichatdaily.com/newsletter See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
In this episode of JCO PO: Article Insights, host Jiasen He summarizes the article, "Clinical Liquid Biopsy Testing for Detection of Actionable Genomic Alterations in Children and Young Adults With Advanced Solid Tumors on the GAIN Study," by Roberts and colleagues. LINK TO FULL TRANSCRIPT
A “safe” AI test environment is supposed to be a sandbox, not a launchpad. Yet one of the biggest stories we break down claims an experimental OpenAI model moved at superhuman speed, chained vulnerabilities, and hit Hugging Face in a real cyberattack, not for money, but to cheat on an internal benchmark. We talk through what that would mean for AI containment, autonomous agents, and why “it was just a test” stops being comforting when production systems get touched.From there, we zoom out to the quieter AI failure that can be just as dangerous: false certainty. Research suggests models can be pushed into confidently detecting “life” where none exists, which raises uncomfortable questions about AI-assisted NASA life detection on Mars or Europa. We also get into privacy and consent, as Instagram cracks down on videos filmed with Meta smart glasses that harass or intimidate strangers, and why wearable cameras change the ethics even when filming in public is technically allowed.Then we get painfully practical. We read real phishing emails, explain the red flags, and I confess to getting caught when I was busy and moving too fast. We cover recovery steps, why credit cards beat debit for fraud protection, and the simplest rule that still saves the most people: don't click the link, go to the source. Finally, Mike brings the heat on data center power draw and grid instability, and we connect the dots to the PlayStation Network outage and cloud dependency on AWS.Subscribe for more tech news for everyday people, share this with someone who needs better scam defenses, and leave a review. What's the one message or alert you almost fell for, and what tipped you off?Send us Fan MailSupport the show
Pastor Daniel teaches that one of the ways to identify a false teacher is that they live according to the flesh.
In this episode, Pastor Daniel and Pastor Ben discuss the recent sermon on Jude 14-16, "The Detection of False Teachers, Part 3: False Teachers Live According to the Flesh."
This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/DYP865. CME/MOC/NCPD/AAPA/IPCE credit will be available until July 2, 2027.Charting a New Course for Alzheimer's: Adapting Clinical Practice to Evolving Patient Needs in the Era of Early Disease Detection and Modification In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Lilly.Disclosure information is available at the beginning of the video presentation.
In a 2014 deception detection study, Pete Blair made 33 judgments—and got all 33 right. That paper was titled “Expertise in deception detection involves actively prompting diagnostic information rather than passive behavioral observation.” I ask Pete about what the factors were in him getting 100% accuracy in that study, and we talk about the interplay between verbal and nonverbal behavior. Pete talks about the importance of context and domain knowledge in making high-confidence judgments, and he discusses how such insights will sometimes be based on aspects that we aren't consciously aware of. Learn more about your ad choices. Visit megaphone.fm/adchoices
Lyle Probst is the CEO of NomadX and an accomplished entrepreneur with more than 25 years of experience in operations, product development, engineering, biodefense, and advanced technology commercialization. Lyle was previously a scientist at Lawrence Livermore National Laboratory and has founded and led multiple companies spanning technology development, manufacturing, biomedical technology, and biological defense. He was part of the team that developed the U.S. BioWatch program and previously served as CEO of MicroFluidic Systems, which, under a contract with the U.S. Department of Homeland Security, developed the M-BAND biological detection system to continuously monitor for biological threats. The system was ultimately licensed by a major defense contractor. Lyle has also designed and shipped multiple mobile command centers and laboratories around the world for several governments and notable private companies. Today, Lyle leads NomadX's mission to help food producers prevent contamination through innovative approaches to detection and decontamination. He has spoken at the U.S. National Academy of Sciences, National BioWatch conferences, and has appeared as a contributor on national media outlets. He is the recipient of several awards and certificates of appreciation from the U.S. Government for his work and contributions to the BioWatch program and related projects. Lyle holds a Bachelor of Science in Biology and an MBA in Executive Management. In this episode of Food Safety Matters, we speak with Lyle [2:18] about: How his background in biodefense, autonomous pathogen detection, and national security led Lyle into food safety, and lessons from biodefense that can be applied to food production and food safety The importance of moving beyond a compliance mindset when it comes to food safety and how recalls and food safety events can impact a business beyond direct costs Industry blind spots related to microbiological contamination control The advancement of rapid pathogen detection technologies and what it means for real-life applications Utilizing pathogen detection data to guide root cause analyses, inform targeted interventions, and prevent recurrence Potential applications for artificial intelligence in food safety What the future of food safety programs may look like in light of advancements in testing, automation, and data integration Advice for food safety leaders as they prepare for the future. Resources The Three-Pillar Food Safety Solution Sponsored by: NomadX We Want to Hear from You! Please send us your questions and suggestions to podcast@food-safety.com
Cyclospora is an uncommon but important cause of prolonged watery diarrhea in children, particularly during the summer months and during foodborne outbreaks. This episode reviews the epidemiology, clinical presentation, diagnostic pitfalls, treatment, and practical emergency department approach to recognizing and managing pediatric cyclosporiasis. Learning Objectives Recognize the clinical features and epidemiology of Cyclospora cayetanensis infection in children, including when to suspect the diagnosis in patients with prolonged watery diarrhea. Select appropriate diagnostic testing for cyclosporiasis and identify the limitations of routine stool cultures, ova and parasite examinations, and gastrointestinal pathogen panels. Apply evidence-based treatment and supportive care for pediatric cyclospora infection, including appropriate antimicrobial therapy, hydration, and follow-up considerations. References Stobbe M. Outbreak of diarrhea-causing parasite grows to more than 1,000 cases. ABC News. Published July 8, 2026. Accessed July 10, 2026. Bilung LM, Tahar AS, Yunos NE, et al. Detection of Cryptosporidium and Cyclospora oocysts from environmental water for drinking and recreational activities in Sarawak, Malaysia. Biomed Res Int. 2017;2017:4636420. doi:10.1155/2017/4636420. Giangaspero A, Gasser RB. Human cyclosporiasis. Lancet Infect Dis. 2019;19(7):e226-e236. doi:10.1016/S1473-3099(18)30789-8. Pyzocha N, Cuda A. Common intestinal parasites. Am Fam Physician. 2023;108(5):487-493. Centers for Disease Control and Prevention. Clinical care of cyclosporiasis. Updated March 8, 2024. Accessed July 10, 2026. Transcript This transcript was generated using Descript and subsequently reviewed and lightly edited for spelling, grammar, and clarity. Minor inaccuracies may remain, and the audio recording should be considered the definitive version of this content. Welcome to PEM Currents: The Pediatric Emergency Medicine Podcast. As always, I'm your host, Brad Sobolewski. It's July and a seven-year-old comes into your emergency department with 10 days of watery diarrhea. They were seen earlier in the week and told it was probably viral gastroenteritis. Maybe they got a prescription for ondansetron, maybe they didn't. Stool cultures have already come back negative. Mom tells you, “Every time I think he's finally getting better, the explosive diarrhea comes right back.” So what's going on? Today we're talking about Cyclospora. Honestly, it's one of those organisms that most of us forget about until summer rolls around, or since medical school. We don't diagnose it every week, and depending on where you practice, you may go years without seeing a case. But then an outbreak happens, and maybe just a handful of sporadic cases show up, and suddenly you're reminded that not every child with prolonged diarrhea has viral gastroenteritis. Cyclospora cayetanensis is a coccidian protozoan that's transmitted through contaminated food or water. In the United States, it's most commonly associated with imported fresh produce, things like cilantro, basil, lettuce, salad mixes, and berries. Unlike bacterial food poisoning, everyone at the picnic usually isn't sick, so it often presents as an isolated illness because the exposure happened days earlier and may have involved only one particular food item. Families are often trying to remember the one thing that they ate that made everybody sick. Honestly, sometimes it's simply the salad they bought at the grocery store a week ago. One thing that's helped me remember these organisms over the years is that they each sort of develop their own personality. You know, it's often confused with Giardia and Cryptosporidium. So if the diarrhea is greasy, think Giardia. If it's profuse, watery diarrhea after swimming, think Cryptosporidium. If it's prolonged, watery diarrhea during the summer, think Cyclospora. Now, obviously there are exceptions, but I think that's a pretty useful framework, especially when you're seeing patients one after another in a busy ED. One of my favorite pearls about Cyclospora, and I think it's probably the one fact that's most worth remembering because it explains how it sort of works. Unlike Giardia or Cryptosporidium, the oocysts that are passed in stool aren't immediately infectious. They actually have to spend days to weeks out in the environment before they mature enough to infect somebody else. So Cyclospora isn't really spread by the kids sitting next to them at daycare. It's spread by the salad they both ate last week. I think that's a lot easier to remember than trying to memorize the organism's life cycle. The incubation period averages about seven to 10 days, so by the time symptoms begin, families usually don't remember exactly what their kid ate. They're certainly not connecting today's diarrhea with the salad they had a week ago. The diarrhea itself is usually watery, sometimes pretty high volume, sometimes even explosive. One thing that's a little deceptive is that it tends to wax and wane. Parents will tell you, “Yesterday I thought we had finally turned the corner,” and today they're right back where they started. Along with the diarrhea, you'll often see abdominal cramping, bloating, nausea, fatigue, maybe even a low-grade fever, and if this has been going on for a while, some weight loss or poor weight gain. Most of these kids don't walk in looking critically ill. They walk in because they're still having diarrhea when everyone expected them to be over it. That's really the patient where Cyclospora should come to mind. And of course, not every child with prolonged diarrhea has it. Giardia is still incredibly common, especially after untreated water exposure, camping, or daycare. Again, those kids have greasy, foul-smelling stools with bloating and flatulence. Cryptosporidium is the swimming pool organism. Those oocysts are remarkably resistant to chlorine, so swimming pools, splash pads, and water parks should all get your attention. Those patients usually have profuse watery diarrhea, but in otherwise healthy children, it tends to run its course over a couple weeks. Cyclospora is different because it just hangs around. That's really what makes me think about it. It's not necessarily how sick the kid is, it's that they're still sick when they should actually be getting better. So aside from when you're in the middle of an outbreak, when should you actually suspect it? It's really when a few things start lining up. The diarrhea has lasted more than a week. Maybe it got a little better and then came back. The kid has lost some weight or looks a little dehydrated. It's summertime. The bacterial stool studies are negative. Maybe there's a history of travel. Maybe there isn't. Maybe there's a history of eating fresh produce. Maybe there isn't. At some point, you have to stop saying, “Eh, it's probably still viral,” and start asking yourself whether you're dealing with something else. One teaching point that's worth repeating, partly because it shows up on board exams and partly because it explains the epidemiology, is that Cyclospora isn't spread directly from person to person. Fresh stool isn't immediately infectious because those oocysts still have to sporulate in the environment before they can infect the next person. So let's say you're thinking about Cyclospora. What do you actually order? A routine stool culture isn't gonna help you. Even a routine ova and parasite examination may not be enough. That's an easy mistake to make because a lot of us were taught persistent diarrhea, send culture and O&P or a stool molecular pathogen panel. Many labs don't specifically look for Cyclospora unless you ask them to or order it specifically. So there's gastrointestinal PCRs for it, but you have to order them separately. So you can actually get back a negative O&P and feel reassured when in reality no one's really tested for Cyclospora. If your hospital has a multiplex GI PCR panel that includes it, that's probably what you should order first. If you don't, you probably have to order it separately. Another board pearl. So if you're taking a board exam and they describe a child with prolonged watery diarrhea during the summer, maybe after eating fresh produce, and then they casually mention that the routine ova and parasite examination was negative, don't let that throw you off. That's actually the clue. The organism may still be there, the lab just wasn't sent to look for it. If your lab is using microscopy, Cyclospora can be identified with a modified acid-fast stain. The oocysts are a little larger than Cryptosporidium, and one interesting feature is that they stain variably. Some stain bright red, while others hardly stain at all, giving them that classic ghost organism appearance, which I think is just, like, cool. And because oocyst shedding is intermittent, collecting two or three stool specimens over several days can improve the diagnostic yield if you still have a high index of suspicion. The good news is that once you make the diagnosis, treatment is actually pretty straightforward. Trimethoprim-sulfamethoxazole remains the treatment of choice. In adult-sized patients, that means trimethoprim one hundred and sixty milligrams plus sulfamethoxazole eight hundred milligrams, just one double-strength tablet, orally twice a day for seven to ten days. For kids greater than two months of age to eighteen years, it's eight to ten milligrams per kilogram trimethoprim and forty to fifty milligrams per kilogram sulfamethoxazole per day orally in two divided doses for seven to ten days. Most children begin feeling noticeably better within twenty-four to forty-eight hours. Honestly, this can be a pretty satisfying infection to treat because families have often been searching for an answer for a week or two. They've been told it's viral. They've been waiting for it to improve, and then you finally make the diagnosis within a day or two of starting the right antimicrobial, the kid's turning the corner. If the kid has a true sulfonamide allergy, things are a little more complicated, and I mean a true allergy, not just the parent who says, “Well, my mother was allergic to sulfa, so we've always avoided it.” There really isn't a perfect alternative. At this point, I'm probably talking to ID. Nitazoxanide's been used, ciprofloxacin's been used, but we generally try to avoid fluoroquinolones in children. Neither has been shown to work as well as trim-sulfa. And if you've got somebody who's immunocompromised with Cyclospora, which fortunately I've never seen, I'd be calling ID. Of course, don't forget everything else that goes along with taking care of prolonged diarrhea. Oral rehydration is still the goal whenever possible. Some kids are gonna need IV fluids because by the time they get to you, they've been losing fluid for days. Replace electrolytes if they've been really sick. And if the illness has dragged on for a couple of weeks, don't forget the nutritional burden. Sometimes they've lost enough weight that getting them eating and drinking normally again becomes part of an ongoing treatment plan. The good news is that most otherwise healthy children recover completely. Immunocompromised patients are the group that worries us the most. Their symptoms can become prolonged. They can relapse. Sometimes they require longer admissions or even secondary prophylaxis. One question that occasionally comes up is whether you need to repeat stool testing after treatment. In general, you don't. If the kid's symptoms have resolved, then you don't need to prove microbiologic cure. Treat the patient, not the PCR. If the kid feels better, you don't need to prove that the pathogen is gone. So let's get back to that hypothetical scenario we started with, that kid in July that's had watery diarrhea for 10 days. The stool culture was negative. They're starting to lose weight. The parents are frustrated. Everyone keeps telling them it's a virus. Maybe it is another virus. Maybe it's two illnesses in a row. But this is the patient where you have to take a step back and consider just one more test instead of offering more reassurance. That's what Cyclospora is. Of course, you shouldn't suspect it in every single child with prolonged diarrhea, but be aware of whether or not there's an outbreak and test for it. Before wrapping this episode up, here's a few more things I'd like you to remember. One, if watery diarrhea has lasted more than a week, especially during the summer months, make sure Cyclospora is somewhere on your differential. Second, remember my comparison. Greasy diarrhea, think Giardia. Swimming pool exposure and profuse watery diarrhea, think Cryptosporidium. Prolonged watery diarrhea during the summer, think Cyclospora. Third, don't let a negative routine ova and parasite examination or stool molecular pathogen panel falsely reassure you. Make sure your laboratory is actually testing for Cyclospora, and remember that not every GI PCR panel includes it. Finally, once you make the diagnosis, treatment is pretty straightforward. Trimethoprim-sulfamethoxazole for most patients. Kids will start feeling better in 24 to 48 hours. Cyclospora isn't the first diagnosis that comes to mind when a kid has diarrhea, and it shouldn't be. Viral gastro is still far more common. But when the diarrhea has been going on for 10 days, the stool studies are negative, the kid's starting to lose weight, and the family says, “I thought we were finally getting better,” that's when you have to stop and think about Cyclospora. It's the child with the diarrhea that lingered. If you enjoyed this episode, as the kids would say, like, rate, and review. Leaving that review on your favorite podcast platform really does help other people discover the show, and I've been fortunate to be teaching through this podcast since 2013 because of listeners like you. If you got ideas for future episodes or topics you'd like me to cover, I'd love to hear them. For PEM Currents: The Pediatric Emergency Medicine Podcast, this has been Brad Sobolewski. See you next time.
SpaceTime with Stuart Gary | Astronomy, Space & Science News
SpaceTime Series 29 Episode 85 Detecting nuclear weapons in space New modelling says small cube-sat sized spacecraft not much bigger than a fridge could be used to detect the presence of nuclear weapons on satellites in space. NASA's rescue mission to save the Swift space telescope reaches orbit NASA's Swift re-boost rescue mission is finally on its way to intercept the gamma ray space telescope and try to save it from its fiery fate. Stopping astronauts from wanting to kill each other on long space trips It can be tough enough getting on with family members at home or the people you have to work with – but imagine what it will be like if you're stuck with a small group of people on a multi-year mission to Mars. The Science Report A new study indicates that people who speak more than one language seem to have younger brains. Warnings that two thirds of Australian adults and a quarter of kids are now overweight or obese. Half of all fatal electric scooter accidents in Sweden are caused by drunk riders. Great news for chocolate lovers with 4 new species discovered. Skeptics guide to the case of the missing peacock. Our Guests This Week: Professor Chris Kirkland from Curtin University NASA planetary geologist Cynthia Phillips Professor Dorothy Carter from Michigan State University And our regular guests: Alex Zaharov-Reutt from techadvice.life Tim Mendham from Australian Skeptics
During last year's massive wildfires in Los Angeles, concerned residents and firefighters went to one app to get up to date information: Watch Duty. Now, the app covers all 50 states and recently added flood tracking to its repertoire. Watch Duty's chief technology officer David Merritt joined Marketplace's Meghan McCarty Carino to talk about how the app is scaling up.
During last year's massive wildfires in Los Angeles, concerned residents and firefighters went to one app to get up to date information: Watch Duty. Now, the app covers all 50 states and recently added flood tracking to its repertoire. Watch Duty's chief technology officer David Merritt joined Marketplace's Meghan McCarty Carino to talk about how the app is scaling up.