Podcasts about Sports medicine

Discover all of the podcasts in our network, search for specific episodes, get the Optimal Living Daily workbook, and learn more at: OLDPodcast.com. Episode 3444: Dr. Neal Malik explains how to build muscle effectively through a combination of heavy compound lifts, proper recovery, and targeted nutrition. Drawing on exercise science and sports nutrition recommendations, he shares practical strategies for protein intake, carbohydrate consumption, and post-workout timing that can help support strength gains and muscle growth. Quotes to ponder: "After a workout the demand for protein is high which makes it the best time to replenish it." "When you lift heavy you also need a longer break in between sets to recover and regain your strength." "Carbohydrates can help our bodies absorb that leucine rich protein more efficiently." Episode references: Bastyr University California: https://bastyr.edu American College of Sports Medicine: https://www.acsm.org Learn more about your ad choices. Visit megaphone.fm/adchoices

All Home Care Matters and our host, Lance A. Slatton were honored to welcome the team from Rock Steady Boxing as guests to the show.   About Ryan Cotton, President/CEO:   Ryan Cotton currently serves as President & CEO for Rock Steady Boxing. His involvement with the organization started in 2009 when he served on the Board of Directors for a decade. Although he serves all RSB boxers around the world, his favorite RSB boxer was his father who was a Parkinson's fighter until his last days.   Ryan's education is in physical therapy where he had a 22-year clinical career before moving into his role at RSB. He holds a Masters in Physical Therapy from the University of Evansville, and a Doctorate in Health Science from the University of Indianapolis.   About Chris Timberlake, Director of Education & Training Rock Steady Boxing:   Chris has been with Rock Steady since 2006 and currently serves as the Director of Training and Education at RSB developing and delivering training in the RSB method to new coaches around the world. She is a caregiver to Tom, who was diagnosed with Parkinson's in 2000, and understands all too well the needs of people struggling with Parkinson's.   Having trained hundreds of people with Parkinson's as well as being immersed as a care partner has given Chris a uniquely intimate perspective on how to battle this disease. She is a Certified Personal Trainer through the American College of Sports Medicine and her personal experience is an instrumental part of Rock Steady's "Cornerman" support.   About Sandra Benton, RSB Boxer, Retired business owner and hairstylist:   Sandra Benton was a business owner for 48 years working as a hairstylist and retiring at age 67. She was diagnosed with PD in April of 2023 and started RSB in July of that year.   About Jim Lindgren, RSB Boxer, Retired reporter and editor:   Jim Lindgren had a career as a newspaper reporter and editor for 25 years before becoming an editor for a market research company and retiring 2 years ago at age 66. He was diagnosed with PD at the age of 61.   About Rock Steady Boxing (RSB):   Rock Steady Boxing (RSB) is a nonprofit organization dedicated to improving the lives of people with Parkinson disease through a specialized, non-contact boxing-based fitness program developed to specifically address the symptoms of Parkinson disease. Founded in Indianapolis in 2006, RSB is built on the belief that individuals with Parkinson's can fight back against the progression of their disease through rigorous, targeted exercise   The RSB program is multimodal and incorporates boxing techniques, strength training, balance work, and cognitive challenges to address the motor and non-motor symptoms of Parkinson's. Backed by growing evidence that high-intensity exercise can slow symptom progression, RSB has become a leader in exercise-based approaches to managing the disease.   Today, Rock Steady Boxing supports a global network of more than 800 affiliate programs that deliver its training in local communities, including gyms, rehabilitation centers, and community organizations. Through comprehensive coach training, ongoing education, and a strong support system, RSB ensures that its programs are accessible, adaptable, and effective for individuals at all stages of Parkinson's. Beyond physical improvements, the organization fosters a powerful sense of community and empowerment among participants, helping them build confidence, connection, and resilience.   As it continues to expand its reach, Rock Steady Boxing remains committed to its mission of enabling people with Parkinson's to live healthier, more active lives.

Host Lindsey Elizabeth Cortes interviews Brittany Miller, a certified sports nutritionist with SwimStrong Dryland who supports swimmers worldwide through a largely virtual program offering strength training, nutrition, wellness, mentorship, and mental skills for athletes from age group to Olympians. Miller shares her personal history of underfueling in softball, later developing restrictive and binge patterns before improving through Precision Nutrition and ASPDA connections, emphasizing scope and referrals to sports dietitians when needed. They discuss swimmer-specific challenges including hidden sweat/hydration, indoor training and low vitamin D, non-weight-bearing bone density risk, early morning two-a-days and underfueling, short recovery windows, nervous stomach at meets, and using interactive, competitive education activities to make nutrition engaging for youth athletes. Brittany Miller is a certified sports nutritionist through Precision Nutrition and the National Academy of Sports Medicine, and is an allied health professional through the American Sports and Performance Dietitians Association. She's been working with swim athletes for over 7 years, from age groupers to Olympians. She and her team at SwimStrong Dryland inspire and change the lives of competitive swimmers through strength training, nutrition & wellness, mentorship and care. As a lifelong athlete, she loves to equip young swimmers with practical knowledge and tools that lead to better performance, more fun, and lifelong habits. Brittany lives on the northside of Indianapolis with her amazing husband, two kids and maltese poodle. Episode Highlights: 01:22 Period Pain Sponsor 03:00 Meet Brittany Miller 04:39 Swim Strong Overview 08:15 Brittany Fueling Journey 15:28 Learning and Support 16:58 ASPD Association 24:34 Reds Resource Break 27:06 Swimmer Nutrition Needs 32:29 Hydration In The Pool 32:47 Tracking Sweat Loss 33:43 Open Water Hydration Challenges 35:36 Swim Culture Two A Days 36:33 Early Morning Fueling Fixes 38:54 Make Nutrition Fun 41:38 Interactive Nutrition Games 44:13 Gamify At Home 52:58 Female Cycle And Fueling 56:43 How To Work With Brittany 58:42 Final Wrap And Resources Resources and Links: SwimStrong Dryland Instagram - @swimstrongdryland SwimStrong Dryland Website - www.swimstrongdryland.com For more information about the show, head to work with Lindsey on improving your nutrition, head to: http://www.lindseycortes.com/ Join REDS Recovery Membership: http://www.lindseycortes.com/reds WaveBye Supplements – Menstrual cycle support code LindseyCortes for 15% off: http://wavebye.co Previnex Supplements – Joint Health Plus, Muscle Health Plus, plant-based protein, probiotics, and more; code CORTES15 for 15% off: previnex.com Female Athlete Nutrition Podcast Archive & Search Tool – Search by sport, condition, or topic: lindseycortes.com/podcast Female Athlete Nutrition Community – YouTube, Instagram @‌femaleathletenutrition, and private Facebook group Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

This episode recorded live at the Becker's 23rd Annual Spine, Orthopedic and Pain Management-Driven ASC + The Future of Spine Conference features Dr. William Levine, Frank E. Stinchfield Professor and Chair, Orthopedic Surgery Department, Chief, Shoulder Service, and Co-Director, Center for Shoulder, Elbow and Sports Medicine, NewYork-Presbyterian Columbia University Medical Center. He discusses navigating financial and operational pressures in academic medicine, expanding ambulatory care, and the leadership principles that help organizations adapt and thrive during times of constant change.

In December 2018 Gatwick Airport shut down. 109 eyewitnesses reported sighting 170 drone flights over the airport.  All flights were grounded, and the nation braced for a terrorist attack. But what if those sightings weren't real but instead an imagination caused by expectations?  In today's episode with award-winning science journalist David Robson, we explore the science of the expectation effect. Link to the bonus episode: https://nudge.kit.com/86d3e39845  Become an FSB member: https://get.fsb.org.uk/nudge/ Read the Expectation Effect: https://amzn.to/4dvkb3s  David's website: https://davidrobson.me/  David's Substack: https://davidarobson.substack.com/ ---  Today's sources:  Benedetti, F., Durando, J., & Vighetti, S. (2014). Nocebo and placebo modulation of hypobaric hypoxia headache involves the cyclooxygenase-prostaglandins pathway. Pain, 155(5), 921–928. Job, V., Dweck, C. S., & Walton, G. M. (2010). Ego depletion—Is it all in your head? Implicit theories about willpower affect self-regulation. Psychological Science, 21(11), 1686–1693. Langer, E., Djikic, M., Pirson, M., Madenci, A., & Donohue, R. (2010). Believing is seeing: Using mindlessness (mindfully) to improve visual acuity. Psychological Science, 21(5), 661–666. Merckelbach, H., & van de Ven, V. (2001). Another white Christmas: Fantasy proneness and reports of 'hallucinatory experiences' in undergraduate students. Journal of Behavior Therapy and Experimental Psychiatry, 32(3), 137–144. Montes, J., Wulf, G., & Navalta, J. W. (2018). Maximal aerobic capacity can be increased by enhancing performers' expectancies. Journal of Sports Medicine and Physical Fitness, 58(5), 744–749. Pirson, M., Ie, A., & Langer, E. (2012). Seeing what we know, knowing what we see: Challenging the limits of visual acuity. Journal of Adult Development, 19(2), 59–67. Robson, D. (2022). The expectation effect: How your mindset can transform your life. Canongate.

This episode recorded live at the Becker's 23rd Annual Spine, Orthopedic and Pain Management-Driven ASC + The Future of Spine Conference features Dr. William Levine, Frank E. Stinchfield Professor and Chair, Orthopedic Surgery Department, Chief, Shoulder Service, and Co-Director, Center for Shoulder, Elbow and Sports Medicine, NewYork-Presbyterian Columbia University Medical Center. He discusses navigating financial and operational pressures in academic medicine, expanding ambulatory care, and the leadership principles that help organizations adapt and thrive during times of constant change.

This episode recorded live at the Becker's 23rd Annual Spine, Orthopedic and Pain Management-Driven ASC + The Future of Spine Conference features Dr. William Levine, Frank E. Stinchfield Professor and Chair, Orthopedic Surgery Department, Chief, Shoulder Service, and Co-Director, Center for Shoulder, Elbow and Sports Medicine, NewYork-Presbyterian Columbia University Medical Center. He discusses navigating financial and operational pressures in academic medicine, expanding ambulatory care, and the leadership principles that help organizations adapt and thrive during times of constant change.

For patient referrals: call 480-733-7400What if one of the most common sports-related injuries was still being treated with outdated advice? In this episode of Beyond the Rounds, we explore two rapidly evolving areas of sports medicine: concussion management and orthobiologic therapies. Dr. Nolan Fisher sits down with sports medicine physician Dr. Evan Werk to discuss why strict rest is no longer considered best practice for concussion recovery, how multidisciplinary treatment is improving outcomes and where therapies such as platelet-rich plasma (PRP) fit into modern musculoskeletal care.For years, concussion management centered on prolonged rest and symptom avoidance. Today, evidence supports earlier return to activity, targeted rehabilitation and individualized treatment plans based on specific symptom patterns. Dr. Werk explains how clinicians can identify concussion subtypes, guide safe return-to-play decisions and address persistent symptoms through coordinated care.The conversation also examines the growing role of orthobiologics, including PRP and bone marrow aspirate therapies. As interest in regenerative medicine continues to grow, understanding what the evidence supports—and where limitations remain—is critical for helping patients make informed treatment decisions.This episode is designed for physicians, advanced practice providers and clinicians seeking practical insights into concussion care, sports medicine and evidence-based approaches to musculoskeletal treatment.What We Cover• Why the "dark room" approach to concussion recovery is outdated• The role of early activity and active rehabilitation after concussion• How concussion subtypes guide treatment decisions• Return-to-play protocols and objective concussion assessment• Persistent post-concussion symptoms and multidisciplinary management• Common misconceptions about regenerative medicine• What PRP is and when it may be appropriate for tendinopathy and osteoarthritis• Bone marrow aspirate therapy and current evidence• The risks of overpromising results from orthobiologic treatments• How sports medicine bridges primary care, rehabilitation and orthopedic surgeryKey Topics for Clinicians• Sports medicine• Concussion management• Return-to-play protocols• Vestibular rehabilitation• Post-concussion syndrome• Platelet-rich plasma (PRP)• Orthobiologics• Bone marrow aspirate therapy• Tendinopathy• Osteoarthritis• Musculoskeletal ultrasound• Exercise medicine• Active aging• Evidence-based sports medicineAbout Our GuestDr. Evan Werk is a board-certified sports medicine physician with Banner – University Medical Group. Trained in both family medicine and sports medicine, he specializes in concussion care, musculoskeletal injuries, ultrasound-guided procedures and orthobiologic therapies. His clinical practice focuses on helping athletes and active individuals safely return to the activities that matter most to them through evidence-based, patient-centered care.He sees patients at: Banner Sports Medicine Scottsdale 7400 N. Dobson Rd., Ste. 201, Scottsdale, AZ 85256Phone: 480-733-7400Fax: 480-207-2118How to Refer a Patient Banner Health providers: Use Cerner's Ambulatory Referral Management (ARM) tool. Community providers: Fax referrals to 480-207-2118 or call 480-733-7400 to schedule a patient for evaluation. Disclaimer This podcast is intended for educational purposes only and is designed for a clinical audience. Any patient scenarios discussed are modified and de-identified to protect privacy. No protected health information (PHI) is disclosed. The information presented should not replace independent medical judgment or individualized patient care decisions. Subscribe to Beyond the Rounds for physician-focused conversations on clinical innovation, specialty collaboration and evolving standards of care.

In this episode of Chewing It Over, Jack sits down with Dr Grainne Donnelly to discuss her newly published textbook on pelvic health in sport, the journey of becoming an editor, and the evolving role of physiotherapists in advancing evidence-based care.Grainne reflects on the enormous challenge of leading a first-edition textbook while simultaneously balancing clinical work, research, teaching, and a PhD. Although initially hesitant to take on such a significant project, she describes how a leap of faith—and encouragement from those around her—led to a resource designed to fill a major gap in sports medicine literature.The conversation explores the growing recognition of pelvic health as a critical component of athletic performance and participation. Grainne discusses the need for better education across professions and highlights the importance of multidisciplinary collaboration in addressing issues that have historically been under-recognised or poorly understood.A particularly interesting section focuses on her research into pelvic floor dysfunction, athletic performance, and the role of compression garments. While acknowledging the influence of confidence, perception, and reduced vulnerability on movement, Grainne also discusses emerging evidence suggesting measurable biomechanical effects, including improved shock attenuation and smoother running mechanics.Throughout the discussion, Jack highlights Grainne's rare ability to bridge clinical practice, research, education, and policy. The episode becomes a wider conversation about curiosity, scientific rigour, and the value of asking better questions rather than rushing to simple answers.Overall, this is an insightful discussion for clinicians interested in sports medicine, women's health, pelvic health, performance, and the future direction of physiotherapy research.

Sugar-Free Diets Disrupted Gut Microbiome and Metabolism A 16-week sucrose-free, low-fat diet study presented at ENDO 2026 found mice developed insulin resistance, impaired glucose tolerance, gut microbiome imbalance, intestinal inflammation, and fatty liver disease signs despite no weight gain or calorie difference. Host Dave Asprey breaks down why eliminating sugar entirely may be more detrimental than previously thought, the gut-bacteria-to-metabolism cascade that explains the metabolic damage, and why balanced nutrition matters more than simply removing sugar from your stack. Sources: https://www.sciencedaily.com/releases/2026/06/260614011843.htm https://www.medicalnewstoday.com/articles/how-eliminating-sugar-may-alter-the-gut-microbiome-mouse-study https://nypost.com/2026/06/13/health/going-sugar-free-can-mess-with-your-gut-and-metabolism/ ~~ Taurine Did Not Boost Acute Aerobic Performance A randomized, triple-blind, cross-over study of 16 physically active young adults found acute 1-gram taurine ingestion one hour before exercise produced no significant improvements in peak oxygen consumption, time to exhaustion, respiratory compensation point, or lipid/glycolytic metabolism variables. Host Dave Asprey explains why taurine remains popular in energy drinks and pre-workouts despite limited scientific evidence, what dosages and activity types future research should test, and why a reality check on a billion-dollar supplement category is exactly the kind of truth biohackers need. Sources: https://pubmed.ncbi.nlm.nih.gov/42268287/ https://www.sciencedaily.com/releases/2026/06/260611024609.htm ~~ Copper Therapy Improved Memory and Reduced Alzheimer's Proteins in Mice Lab trials from Monash University published in ACS Chemical Neuroscience found Cu(ATSM), a copper-delivery compound, increased P-glycoprotein abundance by 24.1 percent at the blood-brain barrier, reduced toxic amyloid-beta by 42 percent over 56 days, and improved spatial learning by nearly 44 percent in an Alzheimer's mouse model. Host Dave Asprey breaks down why repairing the brain's waste-clearing pump is a potential new therapeutic avenue for neurovascular dysfunction, why Cu(ATSM) has strong potential to fast-track into human clinics since it's already tested for Parkinson's and ALS, and why biometal therapies like this could be the next frontier in Alzheimer's treatment. Sources: https://www.news-medical.net/news/20260615/Lab-trials-prove-copper-therapy-enhances-cognitive-function-and-spatial-learning.aspx https://www.monash.edu/news/articles/copper-drug-restores-memory-and-clears-toxic-alzheimers-proteins https://pubs.acs.org/doi/10.1021/acschemneuro.6c00252 ~~ Socioeconomic Factors Biologically Embedded in Children's Brains A study of 2,300+ 9- and 10-year-olds published in Science found socioeconomic factors—household income, education, neighborhood quality—were the dominant variable affecting brain development, with MRI-visible differences in sensory processing and motor control regions linked to less sleep, more stress, and higher social media use in lower-income neighborhoods. Host Dave Asprey explains why socioeconomics became “biologically embedded” in preteen brains, how sleep-stress-screen circuits alter wakefulness and alertness, and why earlier studies focusing on IQ or mental health without accounting for environment may require reevaluation. Sources: https://www.npr.org/2026/06/11/nx-s1-5849937/child-brain-development-stress-sleep-neighborhood-economics https://abcdstudy.org/ ~~ Strength Training Sweet Spot for Longevity Is 90–120 Minutes Per Week A 30-year observational study of 147,374 participants published in the British Journal of Sports Medicine found 90–119 minutes per week of strength training delivered 13 percent lower all-cause mortality, 19 percent lower cardiovascular mortality, and 27 percent lower neurological mortality, with no additional benefit above 120 minutes. Host Dave Asprey breaks down why more isn't always better when it comes to resistance training, why combining strength with aerobic exercise dropped mortality risk by 45–58 percent at highest levels, and why 15–20 minutes a day or 30–40 minutes three times weekly is the minimum effective dose for longevity. Sources: https://www.sciencedaily.com/releases/2026/06/260611024609.htm https://academic.oup.com/sleep/article/48/8/zsaf127/8129074 https://www.bmj.com/content/bsjspor/early/2025/06/11/bjsports-2025-110503 ~~ This episode is designed for biohackers, longevity seekers, and high-performance listeners who want mechanism-level clarity on sugar-free diet metabolic risks, taurine supplement efficacy, copper-based Alzheimer's therapeutics, childhood environmental brain development, and strength training longevity dosing. Host Dave Asprey connects preclinical animal data, randomized human trials, observational cohort research, and population neuroscience into actionable frameworks for extending healthspan, optimizing metabolism, and staying ahead of the science. New episodes every Tuesday, Thursday, Friday, and Sunday. Keywords: sugar-free diet gut microbiome, insulin resistance sugar elimination, taurine aerobic performance, taurine supplement myths, Cu(ATSM) copper Alzheimer's therapy, blood-brain barrier P-glycoprotein, amyloid-beta reduction copper drug, spatial learning Alzheimer's mouse, socioeconomic brain development children, ABCD Study brain MRI, childhood biohacking environment, strength training longevity 90-120 minutes, British Journal Sports Medicine strength, weekly strength training dose, all-cause mortality resistance training, biohacking news 2026, longevity researchThank you to our sponsors! - Viome | Check it out at viome.com and use code 10DAVE for 10% off. It's time to stop guessing and start knowing your body. - Beyond Wonderland Conference | Oct 13 - 14, 2026. Get your ticket now at wonderlandconference.com. - iRestore | Reverse hair loss at www.irestore.com/DAVE and get exclusive savings on the iRestore Elite, use code DAVE Resources: • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Get My 2026 Biohacking Trends Report: https://daveasprey.com/2026-biohacking-trends-report/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 0:00 – Intro 0:20 – Story 1: Copper & Alzheimer's 2:42 – Story 2: Sugar-Free Diet 4:05 – Story 3: Strength Training Minimum Dose 5:48 – Story 4: Childhood Environment & Brain Development 7:42 – Story 5: Taurine 9:49 - Takeaways See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

If you've spent any time on social media or in many gyms lately, you've probably heard the buzz about BPC-157. Often called the "healing peptide," it's being touted as a miracle cure for everything from chronic tendinopathy to acute muscle tears. Patients are showing up in our clinics asking where they can get it, and some "wellness clinics" are already handing out injections like candy.But as sports physical therapists, we have to look past the "bio-hacker" headlines and look at the hard data. Is there actually any human evidence that this works? And more importantly, is it even legal for your athletes to use?A brand-new systematic review just hit the journals, and it's the most comprehensive look we've seen yet at the mechanism, the MSK outcomes, and the massive safety "gray areas" surrounding this compound. The results are fascinating, but they come with some major red flags that every clinician needs to hear before their next patient interaction.In this week's episode, I'm diving deep into the science of BPC-157. We're breaking down the pathways it uses to (potentially) speed up tissue repair, the truth about the current human research, and the legal warnings you must give your athletes to protect their careers.To see full show notes and more, head to: https://mikereinold.com/the-truth-about-bpc-157-peptide-in-sports-medicine-what-you-need-to-know/Learn our proven system for sports PTs who want to master ACL rehab, confidently progress patients, and guide athletes safely back to high-level sport.Click here to learn more Click Here to View My Online CoursesWant to learn more from me? I have a variety of online courses on my website!Disclaimer: This post contains affiliate links. If you make a purchase, I may receive a commission at no extra cost to you.Support the show_____Want to learn more?  Check out my blog, podcasts, and online coursesFollow me:  Instagram  |  Twitter  |  Facebook  |  Youtube

What does it actually take to diagnose REDs, and what happens after? If you've ever wondered what's going on behind the scenes when a sports medicine physician suspects REDs, this episode is your inside look. Host Heather Caplan, RDN, sits down with Dr. Rosa Pasculli, a non-operative sports medicine physician based in Atlanta, to walk through the full medical picture: how REDs gets diagnosed, what labs actually matter and why, and what treatment looks like in practice. It's a masterclass in multidisciplinary care, and a reminder of just how important it is to have a physician on your team who knows how to ask the right questions. Dr. Pasculli is a former competitive dancer turned sports medicine physician with a particular clinical interest in bone stress injuries and REDs. She is the head team physician for Emory University, overseeing 450+ varsity athletes, and serves as a consulting physician for the Atlanta Ballet, the Georgia Ballet, and the Atlanta Falcons Cheerleaders. She also sees runners, weekend warriors, and masters athletes, including, as she mentions in this episode, an 80-year-old woman doing an Ironman. 07:59- How Rosa got into sports medicine and the female athlete space 12:44- What she's seeing in the clinic: awareness of REDs and where education still falls short 14:47- REDs as a diagnosis of exclusion: what that means and why it takes a team 15:51- Lab work 101: CBC, CMP, ferritin, thyroid, and what Rosa is actually looking for 21:48- DEXA scans: who needs one and when, including the Female Athlete Triad Coalition's updated guidelines 24:22- Medical management of REDs: risk stratification, the REDs CAT2 tool, and keeping athletes in sport where possible 25:26- When it becomes dangerous: bradycardia, orthostatic changes, and the malnourished heart 28:34- Setting expectations with patients and parents around timeline and testing frequency 30:31- The Emory Women's Sports Medicine program and the cross-institutional community behind it Resources mentioned: IOC RED-S CAT2 Tool (2023)- free Excel-based risk stratification tool for clinicians Female Athlete Triad Coalition- updated DEXA scan guidelines for adolescent and adult athletes Emory Women's Sport and Wellness Conference- Saturday, August 15th, in-person and virtual; registration opening soon Connect with Dr. Pasculli through the Lane 9 Directory at lane9project.org/directory Connect + get support: Are you an athlete? Find a sports dietitian, DPT, therapist, or coach who understands athletes at lane9project.org/directory. Are you a clinician or coach? If this conversation resonated with you professionally, Lane 9 Membership was built for you. Join a community of dietitians, DPTs, psychologists, sports medicine providers, and coaches who are doing this work, and get listed in the Lane 9 Directory so athletes can find you. Future clinicians and coaches are welcome too. Follow us on Instagram and get in touch anytime!  

Unlocking the Power of Walking: Feet, Movement, and Health.  This episode dives deep into how something as simple as walking is a foundational pillar for health, longevity, and overall well-being. Dr. Karen Litzy welcomes expert insights from Dr. Courtney Conley and Dr. Melissa McDowell, you'll learn practical strategies to optimize foot health, rethink footwear choices, and incorporate walking into everyday life for maximum benefit.  In this episode: ·       Why walking is considered a sixth vital sign and what it means for health assessment ·       The evidence-based optimal step range and busting myths around 10,000 steps ·       How foot strength and proper footwear influence pain, injury, and longevity ·       The biochemistry of walking and its effects on hormones, brain health, and disease prevention ·       Strategies clinicians and individuals can use to operationalize walking as a therapeutic and preventive tool ·       Challenging misconceptions about shoes, orthotics, and barefoot walking Timestamps: 00:00 - Introduction: Rethinking walking as a vital sign and its importance 02:15 - Walking as a necessity: Beyond exercise, a core biological requirement 03:40 - The myth of 10,000 steps: Evidence-based step targets for different health outcomes 05:04 - Micro walks and ambient activity: How small moments add up 06:31 - Meeting people where they are: Tailoring step goals and activity levels 08:32 - Debunking the 10,000 steps myth and the influence of misinformation 09:56 - The impact of walking on mental health and chronic disease management 11:44 - Foot mechanics and gait: Insights into movement patterns and predicting systemic health 13:15 - The importance of foot strength and preserving foot biomechanics over time 14:32 - Foot health's relationship to fall risk and aging 16:54 - Biological impacts of walking on hormones, brain growth factors, and cognitive function 18:14 - Walking as an intervention for menopause symptoms, depression, and anxiety 19:41 - The power of specific step targets for reducing disease risk 21:01 - How walking should be integrated into chronic pain management 23:34 - The simplicity of behavior change: Making walking accessible for everyone 26:54 - Overcoming pain and fear: Starting with micro walks and building confidence 28:01 - Footwear essentials: Respectting anatomy and choosing proper shoes 30:46 - The influence of shoes on foot health, posture, and systemic health 33:33 - Identifying inappropriate footwear and the role of orthotics 35:45 - Addressing footwear for children and the importance of fit during growth 38:31 - The impact of heel-toe drop and shoe structure on gait and health 41:35 - How indoor shoes and surface changes affect foot and overall health 43:54 - Walking and longevity: Connecting foot strength, fall risk, and lifespan 46:22 - Practical tips for strengthening feet and the dark side of cushioned shoes 50:02 - Tips for clinicians to integrate foot health and walking into practice 53:38 - Business opportunities in community health, workshops, and education 56:23 - Final advice for practitioners interested in promoting walking and foot health 57:59 - The journey of publishing a health-focused book: Tips and encouragement 58:06 - The importance of passion and ongoing learning in health professions 66:35 - Resources, social media, and where to find expert guidance Resources & Links: ·       Walk: The Surprising Science of Walking and How It Can Improve Your Health and Happiness ·       Gait Happens - Foot and gait analysis training ·       Melissa McDowell - Instagram | Website ·       Courtney Conley Website| Instagram | YouTube More About Dr. Courtney Conley: Dr. Courtney Conley is the founder of Gait Happens, where she pursues her passion for helping as many people as possible reclaim their foot function. As an internationally renowned foot and gait specialist, Dr. Conley teaches both nationally and internationally. She is a chiropractic physician with a BA in Kinesiology, a BA in Human Biology, and a Doctorate in Chiropractic Medicine. Based in Lakewood, CO, Dr. Conley owns and operates Total Health Solutions clinic and Total Health Performance gym, where she leads patient care focused on restoring gait mechanics and resolving foot problems to help people move more easily and pain-free. She is also a founding member of the Healthy Foot Alliance, an international team of practitioners dedicated to promoting the benefits of natural footwear, preventing unnecessary surgeries, and improving foot function to create a stable foundation from the ground up. More about Dr. Milica McDowell: Dr. Milica McDowell holds two Bachelor of Science degrees (Exercise Physiology and Health Promotion, (Montana State University), a master's degree (Physical Therapy, University of Colorado Health Sciences Center), and a Doctorate degree (Physical Therapy, Idaho State University). She served as a university faculty member in Human Performance for nearly a decade, has developed numerous medical education curricula and has been an invited speaker on many national stages, including the American Physical Therapy Association and American College of Sports Medicine's conventions. She has been an invited presenter for numerous professional organizations, and she has delivered over 300 educational lectures at state, regional, and national levels. Dr. McDowell founded Clearwater Physical Therapy, Bluebird Medical Supply Company, and co-founded Epic Fitness, 4C Sports Injury Analytics, and CrossFit Send It. In 2023, Dr. McDowell was recognized as one of the Top 50 Women Leaders in Healthcare by the Women We Admire organization. She has edited textbooks, written several university science courses, and developed professional continuing education courses that are sold in a global marketplace. One of her present interests is the responsible use of AI technologies to produce multimedia learning experiences in professional education. Jane Sponsorship Information: Book a one-on-one demo here Mention the code LITZY1MO for a free month   Follow Dr. Karen Litzy on Social Media: Karen's Instagram Karen's LinkedIn Subscribe to Healthy, Wealthy & Smart: YouTube Website Apple Podcast Spotify SoundCloud Stitcher iHeart Radio

Dr. Matthew Ithurburn, Director of Clinical Research at the American Sports Medicine Institute (ASMI) in Birmingham, Alabama, joins us to talk about the research shaping the future of sports medicine. Dr. Ithurburn leads ASMI's clinical research team, working alongside Andrews Sports Medicine and Orthopaedic Center on outcomes studies, longitudinal research, and surgical and biologic clinical trials. We dig into what this research means for athletic trainers on the ground, how it's translating into better outcomes for athletes, and where the next breakthroughs in injury prevention and recovery might come from.For more information about PBATS and athletic training, visit pbats.com. 

Dr. Brad Bellard joins The Podfather to discuss the injury severity and recovery timelines for key fantasy football assets: Patrick Mahomes, Malik Nabers, Tank Dell, Chris Olave, Alec Pierce, and many more! Dr. Brad Bellard is a board-certified Sports Medicine physician at CommonSpirit's The Sports Center. He has served as a physician for multiple professional sports teams, including his current role as assistant team physician for the Denver Broncos and his prior role as assistant team physician for the Dallas Mavericks. Whether working with elite pros or everyday fitness enthusiasts, his goal is to help active individuals safely accelerate recovery, break performance plateaus, and optimize their physical health. In his clinical practice, he utilizes cutting-edge regenerative medicine and minimally invasive procedures that help patients avoid the burden of surgery and return to the lifestyle they enjoy. –

Resistance training is one of the most powerful interventions for preserving muscle, supporting metabolic health, and promoting healthy aging—but many patients still find it intimidating or confusing. In this episode, Dr. Kara Fitzgerald sits down with exercise physiologist Brad Currier, PhD, to unpack the newly updated ACSM resistance training guidelines and discuss practical approaches for prescribing exercise across the spectrum, from sedentary adults to elite athletes. In partnership with Timeline, they also review the latest clinical research on Urolithin A, mitochondrial function, muscle recovery, protein, and creatine, offering actionable insights for functional medicine practitioners. Full show notes + references: https://www.drkarafitzgerald.com/fxmed-podcast/ GUEST DETAILS Dr. Brad Currier is Manager of Clinical Trials at Timeline, a Swiss biotech company at the forefront of longevity science for over 15 years. With a background in elite athletics, he went on to earn a PhD in muscle physiology, where his research focused on how exercise and nutrition influence aging and performance. Brad has led numerous clinical trials conducted around the world and published extensively in peer-reviewed journals. He is also the lead author of the American College of Sports Medicine's new position stand on resistance training prescription, helping shape global guidelines for strength training and healthy aging. THANKS TO OUR SPONSOR TIMELINE: http://Pro.timeline.com At the core of Timeline is Mitopure®, a pure and patented form of Urolithin A, shown to improve mitochondrial dysfunction. Learn more & Sign up for a Healthcare Practitioner account at http://Pro.timeline.com Email: care@timeline.com CONNECT with DrKF Want more? Join our newsletter here: https://www.drkarafitzgerald.com/newsletter/ Or take our pop quiz and test your BioAge! https://www.drkarafitzgerald.com/bioagequiz YouTube: https://tinyurl.com/hjpc8daz Instagram: https://www.instagram.com/drkarafitzgerald/ Facebook: https://www.facebook.com/DrKaraFitzgerald/ DrKF Clinic: Patient consults with DrKF physicians including Younger You Concierge: https://tinyurl.com/yx4fjhkb Younger You Practitioner Training Program: https://www.drkarafitzgerald.com/trainingyyi/ Younger You book: https://tinyurl.com/mr4d9tym Better Broths and Healing Tonics book: https://tinyurl.com/3644mrfw

Doug discusses the hip joint, common injuries, treatment options, common hip surgeries, utilization of physical therapy to treat your pain, direct access, and more on the WRAM Morning Show.

What exactly is a traveling fellowship? What are the benefits of doing so? How is orthopedic surgery training in Europe different than the United States? Listen to our latest podcast as we hear about Dr. Lansdown's experience.

The FIFA World Cup and ACL injuries remain one of the most impactful injuries in professional soccer. While much of the discussion around ACL reconstruction focuses on graft choice, rehabilitation, and return-to-play timelines, a new study published in the American Journal of Sports Medicine highlights an often-overlooked challenge: secondary muscle injuries after athletes return to competition.In this episode of Overtime with The Sports Docs, Drs. Ashley Bassett and Catherine Logan review the newly published article, "Secondary Muscle Injuries and Performance Decline After Anterior Cruciate Ligament Reconstruction in Professional Soccer." The study examines the incidence, timing, and impact of muscle injuries following ACL reconstruction in elite soccer players and explores how these injuries affect performance, playing time, and even market value.The findings reinforce an important principle in sports medicine: return to play is not the finish line—it is only the next phase of recovery.Key Discussion PointsUnderstanding ACL Injuries in SoccerCommon mechanisms of ACL injury in soccerWhy cutting, pivoting, deceleration, and landing place soccer players at particularly high riskThe career implications of ACL injuries in professional athletesACL Reconstruction Graft OptionsBone-Patellar Tendon-Bone (BTB) autograftHamstring tendon autograftQuadriceps tendon autograftAdvantages and disadvantages of each graft choiceWhy allograft tissue is generally avoided in elite athletesModern Return-to-Play Decision MakingMoving beyond time-based return-to-play criteriaStrength testing and limb symmetryHop testing and movement analysisNeuromuscular control assessmentPsychological readiness for sportOngoing graft maturation and biologic healingStudy Review: Secondary Muscle Injuries After ACL ReconstructionThe authors evaluated professional male soccer players from Europe's top leagues who underwent ACL reconstruction between 2020 and 2023 and compared them with matched healthy controls.Key findings included:32.5% of ACL-reconstructed players sustained a secondary muscle injury within one year of return to playOnly 12.5% of matched controls experienced muscle injuriesACL-reconstructed athletes were more than twice as likely to sustain a muscle injury after returnMost Common Secondary InjuriesHamstring strains (42%)Quadriceps strains (32%)Calf injuries (16%)Adductor injuries (11%)Notably, nearly 70% of injuries occurred on the reconstructed side, suggesting persistent deficits may contribute to injury risk.The Highest-Risk WindowOne of the most important findings:Nearly 58% of all secondary muscle injuries occurred between 3 and 6 months after return to competitionThis period may represent a critical vulnerability window when athletes are increasing match exposure, training volume, and competition demands.The Importance of the 9-Month RuleThe strongest predictor of secondary muscle injury was early return to play:Athletes returning before 9 months after ACL reconstruction had nearly a fivefold increased risk of secondary muscle injuryThis study adds to the growing body of evidence supporting delayed, criteria-based return to sport rather than return based solely on time.Performance and Career ImpactPlayers who sustained secondary muscle injuries experienced:Reduced playing timeFewer minutes on the fieldDecreased participation metricsDeclines in overall performanceThe study also demonstrated significant reductions in player market value among athletes who experienced secondary injuries, highlighting the financial and career implications of incomplete recovery.Strengths and Limitations of the StudyStrengthsMatched-control designFocus on elite professional soccer playersInclusion of performance metrics and market value outcomesReal-world relevance for sports medicine clinicians and team physiciansLimitationsRetrospective study designRelatively small sample sizeNo objective rehabilitation data availableNo information on graft typeLack of strength testing, hop testing, or psychological readiness measuresNo workload or GPS tracking dataClinical TakeawaysACL recovery extends well beyond return to competition.Return to play should be viewed as a milestone, not the endpoint.The first 3–6 months after return may represent the highest-risk period for secondary injury.Continued strength training, neuromuscular training, and workload monitoring remain essential after athletes resume competition.Returning before 9 months after ACL reconstruction may substantially increase the risk of secondary muscle injury.Successful ACL recovery is not simply about returning to sport—it is about staying healthy and performing at a high level after return.Article Discussed"Secondary Muscle Injuries and Performance Decline After Anterior Cruciate Ligament Reconstruction in Professional Soccer"Published in the American Journal of Sports Medicine (AJSM), 2026.

Episódio sobre o último artigo que publiquei, sobre a promoção de atividade física e sugestões de mudança. Dominski et al. (2026). Human behavioral basis for recomending changes to the physical activity guidelines. Sports Medicine and Health ScienceArtigo disponível abaixo:Human behavioral basis for recommending changes to the physical activity guidelines - ScienceDirect

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The pros are reportedly fuelling with 120 grams of carbohydrate an hour. A new Sports Medicine paper, "Fuelled or Fooled?", asks whether the evidence supports it. For most riders, the short answer is no. We break down what the research actually shows, why anything past 90 grams an hour mostly just sits in your gut, and what to do with your own fuelling.Study: Plews DJ, Booth PD, Krieger T, Maunder E. Fuelled or Fooled? Examining the Evidence and Mechanisms Behind Ultra-High Carbohydrate Intake in Endurance Athletes. Sports Medicine. 2026. https://doi.org/10.1007/s40279-026-02462-zThis week's video - The Alcohol Trap: Why You Should Measure Your Own Limit After 40: https://youtu.be/4rXeEVf22poWant a coach reading the load that does not show up in your file? SEMIPRO Guided: https://go.semiprocycling.com/go/cce4nxDaily cycling intelligence from SEMIPRO CYCLING, produced with AI-assisted research, scripting, and synthetic voice.

  We are continuing our series of podcasts called “Pediatric Sport Medicine Profiles.” There have been some individuals who have been significantly influential in this pediatric sports medicine, whether it be training many of us, people who have completed critical research, those who have been […]

Have you been overcomplicating strength training after 40? If you've ever wondered whether you're doing the "right" workout, lifting heavy enough, following the perfect program, or spending enough time in the gym, this episode may be exactly what you need to hear. A major new research review from the American College of Sports Medicine looked at 137 studies involving more than 30,000 people and came to a surprisingly simple conclusion: the biggest difference isn't between workout program A and workout program B. The biggest difference is between doing nothing and doing something. In this episode, I'm breaking down what the latest science says about strength training, why consistency matters more than perfection, and how strength training to lose weight can be much simpler than you've been led to believe. We'll talk about the best approach to building muscle, supporting hormones, improving metabolism, and using strength training as one of the most effective belly fat loss exercises available to women in perimenopause and menopause. Friend, your body doesn't need perfection. It needs participation.   FULL BLOG + SHOW NOTES Read the full article and grab the resources mentioned in today's episode:

Send us Fan MailIn this episode, I'm joined by Gráinne Donnelly, an Advanced Practice Pelvic Health Physiotherapist and doctoral researcher. She is also the editor of the new textbook Sports Medicine and the Pelvic Floor: Science to Practice, which bridges the gap between research and clinical care for active women.We dive into the latest research on postpartum recovery, including the growing interest in external support garments and pelvic compression shorts. Gráinne shares what the evidence currently shows, where these garments may fit into rehabilitation, and why graded loading remains an important principle when returning to running and impact activities. We also discuss the challenges of translating research into practice, combating misinformation on social media, and staying open to changing recommendations as new evidence emerges.We talk about:-Graded loading when returning to running-Speed walking and grounded running-The effectiveness of pelvic compression garments-Collaboration between clinicians and researchers-Combating social media misinformation-Bridging the gap between research and clinical practiceTime Stamps1:00 introduction5:46 updates on the research11:40 external support garments20:24 clinical implications23:24 Sports Medicine and the Pelvic Floor - Science to Practice book33:13 planning for what is next41:50 storytelling as a form of health communication49:30 reexamining advice you give patients as you learn more CONNECT WITH CARRIEIG: https://www.instagram.com/carriepagliano/Website: https://carriepagliano.comCourse waitlist: https://course.carriepagliano.com/RSAWLCONNECT WITH GRÁINNE:Instagram: https://www.instagram.com/grainnedonnelly_absolutephysio/Website: www.absolute.physioThe Active Mom Podcast is A Real Moms' Guide to pregnancy, postpartum, perimenopause & beyond for active moms & the professionals who help them in their journey.  This show has been a long time in the making!   You can expect conversation with moms and professionals from all aspects of the industry.   If you're like me, you don't have a lot of free time (heck, you're probably listening at 1.5x speed), so theses interviews will be quick hits to get your the pertinent information FAST!  If you love what you hear, share the podcast with a friend and leave us a 5 ⭐⭐⭐⭐⭐ rating and review. It helps us become more visible in the search algorithm! (Helps us get seen by more moms that need to hear these stories!!!!)

I'm joined by Dr. Jeffrey Sankoff to talk about three exercise “rules” you may be allowed to break: you don't always need to spread workouts across the week, intensity doesn't have to come from a formal interval session, and most short workouts don't require a complicated hydration or fueling plan.The Exercise Rules You're Allowed to BreakHave you ever skipped a workout because you couldn't do the “right” one? Maybe you didn't have time for the gym, a long hike, or a structured bike ride. Today, we revisit Voltaire's reminder that “the great is the enemy of the good” and apply it to exercise. The evidence is reassuring: weekend workouts count, short bursts of effort during the day count, and for most workouts under an hour, hydration hype may matter far less than we've been led to believe.Dr. Jeffrey Sankoff, an ER physician, Ironman triathlete, triathlon coach, and host of the evidence-focused TriDoc Podcast, joins me for this conversation. While Jeff works with endurance athletes, today's discussion is for anyone who wants to live long and well while still managing the realities of work, family, travel, and everyday life.First, we break the calendar rule. Many people assume exercise has to be spread evenly throughout the week, but a 2024 Circulation study on “weekend warrior” physical activity found that people who concentrated their moderate-to-vigorous exercise into one or two days still had lower risk for many diseases compared with inactive people, especially cardiometabolic conditions such as hypertension, diabetes, obesity, and sleep apnea. The study was observational, so it does not prove weekend-only exercise is ideal, and injury risk still matters. But the practical message is clear: if weekdays are impossible, weekends still count. Next, we break the formal-interval rule. High intensity does not always have to mean a structured HIIT class, a bike trainer, or a carefully timed workout. A 2026 European Heart Journal study found that a higher percentage of vigorous physical activity was associated with lower risk across several chronic diseases and mortality outcomes. Even a small proportion of vigorous activity may matter, meaning short real-life bursts—taking the stairs quickly, walking briskly uphill, carrying groceries with purpose, or chasing a child or grandchild—can become meaningful movement when they raise your breathing and effort level. This study was also observational, so it cannot prove cause and effect, and anyone with medical concerns should check with their clinician before adding vigorous bursts. Finally, we break the bottle rule. For endurance races, long workouts, or hot-weather exercise, hydration, electrolytes, and carbohydrates can matter. But for many 30- to 60-minute workouts in ordinary conditions, a formal hydration or fueling plan may not be necessary. The American College of Sports Medicine's position stand emphasizes fluid replacement to support hydration during physical activity, but the need depends on duration, sweat loss, heat, and intensity. A practical “N of 1” approach is to weigh yourself before and after a typical workout to see how much fluid you actually lose. We also discuss electrolytes and carbohydrates. Electrolytes are mostly salts, and they become more relevant with long, hot, sweaty, or repeated sessions. Carbohydrate-containing drinks can help with longer endurance performance, but for a 35-minute walk or a short gym session, sugar in your bottle is usually not the bottleneck. A systematic review on carbohydrates and exercise performance found benefits in longer exercise contexts, but that does not mean every short workout needs sports drinks or gels. TakeawaysDon't let the perfect workout plan keep you from the good-enough workout you can actually do.If weekdays are packed, a weekend warrior approach may still provide meaningful health benefits.Look for small bursts of vigorous effort in daily life, and for most workouts under an hour, water when thirsty is usually enough.Send us Fan MailSupport the show

In this episode with Mitchell Selhorst, we discuss a recent paper in which he was lead author looking at standard care of spondylolysis. We explore:  ·       What is spondylolysis?·       Prevalence of spondylolysis·       Standard care of spondylolysis·       Evidence based care of spondylolysis e.g. “Immediate functional progression program”·       Role of education in this population

You're mid-combo, nailing your choreography, and suddenly—snap! The floor shifts beneath you, pain shoots up your leg, and your rehearsal dreams hit pause. This week on Performers Happiness in the Arts (PHARTS), Jenna Kantor, PT, DPT—dance medicine specialist and performer—dives deep into one of the most common and frustrating injuries for musical theatre artists: the ankle sprain. Whether you're a dancer landing from a tour jeté, a singer gliding across stage in character heels, or an actor pivoting during a quick scene change, your ankles are the unsung heroes of your performance. Learn how to spot the difference between a mild twist and a true sprain, why these injuries happen so often onstage, and what the science says about your recovery timeline. We'll also unpack research showing that up to 70% of dancers experience an ankle injury during their career (Steinberg et al., Tel Aviv University, 2011) and discuss how even minor sprains can affect balance, mobility, and confidence long after the swelling fades. This episode walks you through: The anatomy behind a sprain (why the ATFL is always in the spotlight) What the healing phases really look like for performers How to safely return to turns, jumps, and stage movement Evidence-based prevention tools that keep you performing pain-free ✨ Referenced Research: Steinberg, N., Hershkovitz, I., et al. (2011). Injuries in Dancers: Prevalence and Patterns. Tel Aviv University, Israel. Fong, D. T.-P., et al. (2009). A Systematic Review on Ankle Injury and Sprain in Sports. Sports Medicine, 39(1), 73–94. Garrick, J. G. (2017). Ankle Sprains and Chronic Instability in Athletes. Clinics in Sports Medicine, 36(1), 13–28.

What is weight-inclusive care? And why does it matter for *all* active women's health and performance?Dr. Erin Ayala sits down with Dr. Heather Bergeson, a sports‑medicine physician and co‑director of the TRIA Women's Sports Medicine program, to unpack five decades of fitness and diet fads. Past trends still shape today's wellness culture — and even if you think you're immune, you're not.Key TakeawaysFollow the evolution of fitness and diet fads from the 1970s thin‑ideal to today's protein-heavy, weighted‑vests—and understand how each era reinforces or challenges body‑image norms.Why BMI is an unreliable health metric and how weight‑inclusive care improves patient outcomes and satisfaction.Actionable steps for clinicians and coaches (e.g., avoid routine weighing, use neutral language, provide size‑accessible equipment)And practical tips for listeners to break free from diet culture: ditch diet apps, focus on intuitive eating, prioritize sleep, and limit comparison‑driven fitness tracking.Episode Resources:TRIA Women's Sports Medicine program: https://www.healthpartners.com/care/tria-orthopedics/services/womens-sports-medicine/Join us at Feisty Fest - September 18-20th, 2026: https://feisty.co/events/feisty-fest/Sign up to Receive The Feisty Women's Performance Newsletter:https://feisty.co/newsletters/feisty-womens-performance/Follow us on Instagram:@feisty_womens_performanceVisit the Feisty website at https://feisty.co/ for info on all of our events and podcastsSupport our Partners:Momentous: Head to https://www.livemomentous.com/ and use promo code PERFORMANCE for up to 35% off your first orderHettas: Use code STAYFEISTY for 20% off at https://hettas.com/ Wahoo: Learn more about Wahoo Fitness Products at: Wahoo: Learn more at https://shorturl.at/WVhdr Tifosi Optics: Use code FEISTY2026 for 20% off at https://tifosioptics.com/If you found this conversation valuable, hit subscribe so you never miss an episode, and leave a review on your favorite platform. Have questions or topics you'd like us to explore? DM us on Instagram.

What exactly is blood flow restriction therapy? How is it used in rehabilitation? Listen to our latest podcast as we sit down with BFR pioneer Johnny Owens.

This week on the Science for Sport podcast, Richard Graves welcomes Matt Parr back to the show for a deeper look at the work that really drives performance in elite sport. Matt is the Head of Athletic Performance at Leicester Tigers, a former professional rugby player, and the founder of High Performance Puzzle. Having worked across both rugby union and rugby league, including Leicester Tigers and Catalan Dragons, Matt brings a rare combination of playing experience, coaching insight, leadership responsibility, and high-performance strategy. In this episode, Richard and Matt explore the “invisible work” that sits behind successful performance environments. Not the gym programme. Not the GPS report. Not the testing data. But the conversations, decisions, relationships, standards, and judgement calls that determine whether the physical work actually lands. They discuss why data needs context, how performance teams can align with coaches under pressure, what good decision-making looks like when information is incomplete, and why trust remains one of the most important currencies in elite sport. For sports science, S&C, medical, coaching, and performance staff working in elite environments, this episode is a valuable reminder that high performance is not built by data alone. It is built through people, relationships, standards, and the ability to make good decisions when the pressure is on. In this episode you will learn Why the work that drives performance often sits outside the formal programme, session plan, or data report How conversations between coaches, medical staff, S&C, sports science, and players provide vital context What good alignment looks like in a high-performance environment How to manage differing opinions between technical and performance departments Why frameworks are essential when emotions and pressure start to influence decision-making How to make better decisions when you do not have the complete picture Why trust between the head coach, medical team, and performance staff is critical How to use data without becoming over-reliant on it Why standards often slip in small ways before they show up in performance outcomes How relationships can make or break the effectiveness of even the best performance systems Why gut feel still matters, provided it is shaped by experience and reflection How elite practitioners can reflect more effectively on their own decisions and behaviours Why discipline is a habit, not just a personal trait What Matt has learned from working across rugby union and rugby league Why the best players want honest feedback when standards start to slip About Matt Parr Matt Parr is Head of Athletic Performance at Leicester Tigers and founder of High Performance Puzzle. Before moving into strength and conditioning, Matt spent around 14 to 15 years as a professional rugby player, representing clubs including Sale Sharks, Saracens, London Irish, and Leicester Tigers. His transition into performance coaching began at Leicester Tigers, where he initially combined a player-coach role with S&C responsibilities before moving fully into the performance department. Matt has since built extensive experience across both rugby union and rugby league. After progressing through the performance setup at Leicester Tigers, he joined Catalan Dragons as Head of Performance, before returning to Leicester as Head of Athletic Performance. Alongside his role in professional rugby, Matt has launched High Performance Puzzle, a consultancy focused on high-performance strategy, systems, leadership, and integration. FREE 7d SCIENCE FOR SPORT ACADEMY TRIAL SIGN UP NOW: https://bit.ly/SFSepisode241 ​ Learn Quicker & More Effectively ​ Optimise Your Athletes' Recovery ​ Position Yourself As An Expert To Your Athletes And Naturally Improve Buy-In ​ Reduce Your Athletes' Injury Ratese ​ Save 100's Of Dollars A Year That Would Otherwise Be Spent On Books, Courses And More ​ Improve Your Athletes' Performance ​ Advance Forward In Your Career, Allowing You To Earn More Money And Work With Elite-Level Athletes ​ Save Yourself The Stress & Worry Of Constantly Trying To Stay Up-To-Date With Sports Science Research

Being overweight and being unfit are not the same thing. That's the central finding of a new meta-analysis published in the British Journal of Sports Medicine and it carries significant implications for how fitness operators communicate the value of exercise to members. Hosts Rachel Chonko and Luke Carlson break down the findings of the meta-analysis examining how cardiorespiratory fitness — not body weight — predicts mortality risk. The research synthesized 716 individual studies over 20 meta-analyses, making it one of the most comprehensive looks at this question to date. This Episode Covers: - Why the fitness industry has historically conflated weight loss with fitness, and how that messaging has done members a disservice - The "fit-fat paradigm" explained: why an overweight individual with strong cardiorespiratory fitness can carry the same mortality risk as a normal-weight fit person - Why clubs investing in longevity programming should anchor those offerings in evidence-based aerobic exercise rather than less-studied modalities like cold plunge or infrared therapy - How operators can reframe the member value proposition — shifting the conversation from how exercise changes your body to how it extends your life

Dr. Michael Skyhar is a board-certified orthopedic surgeon specializing in sports medicine. He provides expert care for a wide range of orthopedic conditions and injuries, with particular expertise in knee and shoulder arthroscopy, rotator cuff repair, joint aspiration and drainage procedures, and other advanced surgical treatments. Dr. Skyhar's treatment philosophy emphasizes comprehensive, patient-centered care, combining both operative and non-operative approaches to orthopedic injuries and disorders. He is committed to pursuing conservative treatment options whenever appropriate while delivering precise surgical intervention when necessary to achieve the best possible outcomes. In addition to his clinical practice, Dr. Skyhar has published and presented numerous articles on sports medicine injuries and advancements in orthopedic care. He is an active member of the American Academy of Orthopaedic Surgeons, the American Orthopaedic Society for Sports Medicine, and the California Medical Association. He also previously served as Chief of Staff at Scripps Memorial Hospital Encinitas. Dr. Skyhar is dedicated to helping patients return to an active, healthy lifestyle through personalized treatment plans, advanced surgical techniques, and compassionate care.

Doctor Mau Informa ®️ #drmauinforma Cuando discutimos la diabetes tipo 2 y la prediabetes, nuestro enfoque se centra casi exclusivamente en restringir los carbohidratos y perder peso. Sin embargo, los datos de los ensayos clínicos más recientes revelan un punto ciego enorme en nuestros paradigmas de atención: el músculo esquelético es nuestro órgano de eliminación de glucosa más grande, e ignorarlo acelera el envejecimiento metabólico. En este episodio, desglosamos las pautas clínicas y los datos de ensayos más recientes que demuestran por qué el entrenamiento de hipertrofia mecánica funciona como una poderosa intervención no farmacológica para el control del azúcar en sangre, incluso para personas con un peso normal. En este episodio aprenderás: → Por qué la diabetes tipo 2 actúa como un factor de riesgo independiente para la sarcopenia acelerada y el declive de la función muscular. → Los datos moleculares que demuestran que el entrenamiento de resistencia mejora la HbA1c en aproximadamente un 0.57% y la glucosa en ayunas en ~7 mg/dL. → Por qué el entrenamiento de hipertrofia es significativamente superior al entrenamiento de resistencia a la fatiga para la inflamación sistémica y la retención de masa magra. → Los sorprendentes resultados del ensayo Kobayashi: por qué el entrenamiento de fuerza venció al cardio en la diabetes tipo 2 de peso normal. → Los parámetros de programación exactos de la Asociación Americana de Diabetes y el ACSM necesarios para optimizar la eliminación metabólica en la práctica.

The Tommy John epidemic has become one of the most pressing issues in baseball and in this episode of The Research Rundown, we bring together five of the game's leading sports medicine minds to tackle it head on. Dr. Michael T. Freehill, Head Team Physician, and Brian Schulman, Director of Sports Medicine and Performance of the Athletics, join Dr. Steven B. Cohen, Head Team Physician, Paul Buchheit, Head Athletic Trainer, and Joe Rauch, Assistant Athletic Trainer of the Philadelphia Phillies for a wide-ranging roundtable on the data, the causes, and what baseball needs to do next.For more information about PBATS and athletic training, visit pbats.com. 

Save 20% on all Nuzest Products WORLDWIDE with the code MIKKIPEDIA at www.nuzest.co.nz, www.nuzest.com.au or www.nuzest.comThis week on the podcast, Mikki speaks to Brad Currier, Science Lead at Timeline Nutrition and lead author of the recent American College of Sports Medicine position stand on resistance training.In this episode, the conversation begins with Urolithin A and Mitopure, exploring what it is, what it does in the body, and why it has become an area of interest for mitochondrial health and muscle function. Brad explains the proposed mechanisms, the current human evidence, and what outcomes have actually been shown to improve, from cellular-level changes through to potential real-world benefits.Mikki and Brad also discuss who may be the best fit for a supplement like this, including older adults, athletes, and those already doing the fundamentals well, while also addressing the limitations of the current research and how to think about bias when science and industry intersect.The conversation then shifts to resistance training, where Brad shares key takeaways from the ACSM position stand he led, including what matters most for strength, hypertrophy, and health, and what people can probably stop overthinking.It's a balanced, evidence-informed conversation about mitochondrial health, supplementation, strength training, and the practical foundations that still matter most.Brad Currier is the Science Lead at Timeline Nutrition, where his work focuses on translating emerging research on mitochondrial health into practical, evidence-based applications. In particular, he has been closely involved in the science and communication around Urolithin A, the active ingredient in Mitopure, and its potential role in supporting muscle function, cellular energy, and healthy ageing.With a background in exercise science and resistance training research, Brad brings a dual lens to his work—combining performance-focused insights with a broader interest in longevity and metabolic health. He has contributed to large-scale evidence syntheses in resistance training, helping clarify what actually matters for strength, hypertrophy, and overall health, and where the field may have overcomplicated things.At Timeline, his role sits at the intersection of research, education, and application, helping bridge the gap between mechanistic science, clinical relevance, and real-world use—particularly as interest grows in interventions that support muscle and mitochondrial function across the lifespan.Brad Currier https://www.instagram.com/bradcurrier.phd/• ACSM Position Stand on Resistance Training (2026) - https://journals.lww.com/acsm-msse/fulltext/2026/04000/american_college_of_sports_medicine_position.21.aspx• Timeline Nutrition - https://www.timeline.com• Curranz Supplement: Use code MIKKIPEDIA to get 20% off your first order - go to www.curranz.co.nz  or www.curranz.co.uk to order yours NZ listeners - save 10% off Calocurb by using the code Mikkipedia10 at www.calocurb.co.nzContact Mikki:https://mikkiwilliden.com/https://www.facebook.com/mikkiwillidennutritionhttps://www.instagram.com/mikkiwilliden/https://linktr.ee/mikkiwilliden

On this episode of Inside Startup Investing, Chris Lustrino speaks with Dr. Michael Wyand, CEO of Oxeia Biopharma, a clinical-stage biotech company developing a potential breakthrough treatment for concussions and persistent concussion symptoms. Oxeia is leveraging ghrelin, a naturally occurring hormone involved in brain energy regulation and neural repair, to help heal the inflammation and cellular damage caused by traumatic brain injuries. With promising Phase 2a data showing an 85% responder rate among treated patients, the company is pursuing what could become the first FDA-approved pharmaceutical treatment specifically targeting concussion recovery. Chris and Michael discuss the science behind concussions, how brain damage occurs after impact, why “just rest” has remained the standard of care for decades, and how Oxeia's therapy could fundamentally change the treatment landscape for athletes, veterans, and millions of patients suffering from lingering neurological symptoms. They also dive into the company's clinical pathway, the business opportunity behind concussion therapeutics, the role of neurogenesis in recovery, and the broader future potential for treating conditions like CTE, Parkinson's disease, and ALS. If you want to understand the future of concussion recovery, brain health innovation, and biotech investing, this is an episode you won't want to miss.

Are your workouts actually building strength or just burning time? Amy Hudson and Dr. James Fisher break down the latest 2026 guidelines from the American College of Sports Medicine on how you should be training today. They unpack why consistency beats perfection, how minimal training can still deliver real results, and where most people waste time and effort. Tune in to simplify your approach and start training in a way that actually works.Dr. Fisher explains what the American College of Sports Medicine (ACSM) actually does. It's one of the main bodies shaping exercise science, from research journals to certifications that guide the industry.Dr. Fisher shares why resistance training is still massively underused. Around 60% of adults aren't doing any strength work, and only a small percentage hit the basic guideline of twice per week.Learn why consistency will always beat the “perfect program.” You don't need the smartest plan on paper if you're not showing up for it. What actually moves the needle is turning up regularly and putting in some effort, even on the days it feels basic.Amy covers how to choose a program you'll actually stick with. There's no shortage of “best” routines out there, but most of them fail because people don't follow through. The real win is picking something that fits your life so well that skipping it starts to feel uncomfortable.Dr. Fisher explains how to progress your training without overthinking it. If the weight, reps, or sets aren't gradually increasing, your body has no reason to adapt. Progress doesn't have to be dramatic, but it does need to be intentional.Amy covers why a personal trainer can quietly make all the difference. Most people fall into the habit of repeating the same weights and routines because it feels comfortable. A good personal trainer steps in to push progression just enough to keep you improving without burning out.Learn how working with a personal trainer improves more than just your results. You're not just getting guidance, you're also getting accountability, structure, and a reason to show up. That consistency alone is often what separates people who see change from those who stay stuck.Dr. Fisher explains why resistance training feels complicated (but isn't). Many people avoid it because they're unsure where to start or think it takes too much time. In reality, even two short 20-minute sessions a week can deliver meaningful results if done properly.Amy covers how to keep strength training simple and effective. Building strength is naturally repetitive. You don't need constant variety; you need consistency in doing what already works.Amy and Dr. Fisher agree that the basics will always outperform every “new hack.” Sleep well, eat decently, and challenge your muscles regularly is the foundation. Amy adds that it's easy to chase complexity, but most results come from doing simple things well over time.Dr. Fisher explains how eccentric overload can unlock more strength. Traditional weights give you the same resistance up and down, which limits how much you can challenge the muscle. With advanced tech like exerbotics devices, the lowering phase can match your strength more closely, creating a stronger stimulus and better results. Mentioned in This Episode:The Exercise Coach - Get 2 Free Sessions!Submit your questions at StrengthChangesEverything.com This podcast and blog are provided to you for entertainment and informational purposes only. By accessing either, you agree that neither constitute medical advice nor should they be substituted for professional medical advice or care. Use of this podcast or blog to treat any medical condition is strictly prohibited. Consult your physician for any medical condition you may be having. In no event will any podcast or blog hosts, guests, or contributors, Exercise Coach USA, LLC, Gymbot LLC, any subsidiaries or affiliates of same, or any of their respective directors, officers, employees, or agents, be responsible for any injury, loss, or damage to you or others due to any podcast or blog content.

Is more always better? Is there a dose response effect of exercise for musculoskeletal pain? Should exercise be just like a medication, where the dose has to be sufficient in order for it to elicit a therapeutic effect? These are the questions we contend with on this episode of The Shoulder Physio Podcast. Key resources Lawford BJ, Hinman RS, Spiers L, Kimp AJ, Dell'Isola A, Harmer AR, Van der Esch M, Hall M, Bennell KL. Does Higher Compliance With American College of Sports Medicine Exercise Prescription Guidelines Influence Exercise Outcomes in Knee Osteoarthritis? A Systematic Review With Meta-Analysis. Arthritis Care & Research. 2024. Liang X, et al. The Best Exercise Modality and Dose for Reducing Pain in Adults With Low Back Pain: A Systematic Review With Model-Based Bayesian Network Meta-analysis. JOSPT. 2024. Malliaras P, Johnston R, Street G, Littlewood C, Bennell K, Haines T, Buchbinder R. The efficacy of higher versus lower dose exercise in rotator cuff tendinopathy: A systematic review of randomised controlled trials. Archives of Physical Medicine and Rehabilitation. 2020. Powell JK, Lewis J, Schram B, Hing W. Is exercise therapy the right treatment for rotator cuff-related shoulder pain? Uncertainties, theory, and practice. Musculoskeletal Care. 2024. Powell JK, Lewis JS. It is not all about strength: rethinking mechanistic assumptions in exercise-based rehabilitation. British Journal of Sports Medicine. 2025. Register for the complete shoulder online course Register for my Brisbane workshop Connect with Jared and guests: Jared on Instagram: @‌shoulder_physio Jared on X: @‌jaredpowell12 See our Disclaimer here: The Shoulder Physio - Disclaimer

Listen to our latest podcast as Dr Brian Feeley and Dr Nirav Pandya breakdown the decision making that goes into treating ACL tear, meniscus injuries, and rotator cuff pathology in our latest podcast.

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In this episode of Bleav in Rams presented by Fanduel, Erin Coscarelli and Rams Super Bowl Champion Rob Havenstein have an insightful and impactful discussion with LA Rams Senior Vice President of Sports Medicine and Performance, Reggie Scott, on the ever-evolving world of NFL performance, recovery, and player development. What is the ONE trait that ultimately determines which players succeed in the NFL? What do the Rams do with rookies when they FIRST enter the building? Which stretch of the Rams' calendar is most physically demanding? Why is trust so important when it comes to the foundation of modern sports science...? Plus an interesting perspective on how veteran offensive lineman Rob Havenstein changed the way the organization evaluates talent... This conversation goes far beyond football. An INSIDE lens how the Rams use data, recovery, and individualized performance to gain an edge. The future of elite sports and why the Rams continue to lead the way... Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

In this episode of Bleav in Rams presented by Fanduel, Erin Coscarelli and Rams Super Bowl Champion Rob Havenstein have an insightful and impactful discussion with LA Rams Senior Vice President of Sports Medicine and Performance, Reggie Scott, on the ever-evolving world of NFL performance, recovery, and player development. What is the ONE trait that ultimately determines which players succeed in the NFL? What do the Rams do with rookies when they FIRST enter the building? Which stretch of the Rams' calendar is most physically demanding? Why is trust so important when it comes to the foundation of modern sports science...? Plus an interesting perspective on how veteran offensive lineman Rob Havenstein changed the way the organization evaluates talent... This conversation goes far beyond football. An INSIDE lens how the Rams use data, recovery, and individualized performance to gain an edge. The future of elite sports and why the Rams continue to lead the way... Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Dr. Deb Muth 00:04What if the future of healing isn’t about replacing cells, but about teaching your body how to heal itself again? We keep hearing the words stem cells and exoomes thrown around like they’re interchangeable, but they’re not. One is regulated, controversial, and often misunderstood. The other is rapidly emerging as one of the most exciting communication systems in human biology. Dr. Deb Muth 00:33And here’s the real question no one’s asking. Are we actually regenerating tissue or are we just stimulating the body to remember how it used to heal? Tired of being told your labs are normal, but you still feel terrible? At Serenity Healthcare Center, we don’t chase symptoms. We find the root cause. hormones, gut health, autoimmune conditions, chronic fatigue, brain fog. Dr. Deb Muth 01:02We use cuttingedge functional and regenerative medicine to get you real answers and a real path forward. This isn’t your average doctor’s office. This is medicine the way it was meant to be practiced. You deserve to feel like yourself again. Visit serenityhealthcarecenter.com to book your appointment today. Let us help you heal from the inside out. Dr. Deb Muth 01:28Welcome back to Let’s Talk Wellness Now. I’m Dr. Deb, your host. And if you’ve been following regenerative medicine, you’ve probably noticed the confusion. Patients are asking me every week, are exoomes stem cells? Are stem cells legal in the United States? I heard the FDA is shutting down all these clinics. Can I even get this therapy? Do I have to leave the country for treatment? Today, we’re cutting through the noise. This episode is not hype. Dr. Deb Muth 01:54It’s not sales. It’s education so you can understand the science, the regulatory reality, and the clinical difference between stem cell therapy and exoome therapy. And here’s what I want you to know right up front. Yes, these therapies are being used in the United States every single day. Yes, they’re being offered by highly trained physicians in integrative and regenerative medicine clinics across the country. Dr. Deb Muth 02:22Some are being used in FDA registered clinical trials. Some are being used in observational studies and some are being used in clinical practice under physician discretion. The landscape is nuanced and you deserve to understand it. So, grab your cup of coffee or tea and settle in for a deep dive into the most understood therapies in regenerative medicine. Dr. Deb Muth 02:43what they actually are, how they work, the regulatory landscape, and how they might support your body’s natural healing capacity. Let’s talk wellness now. So, let me start by asking you something. When you hear the word stem cell, what do you picture? Most people imagine damaged tissues magically regenerating or a torn meniscus growing back, cartilage reforming it into an arthritic joint or damaged brain tissue being replaced with healthy new beautiful cells. It’s a beautiful vision. Dr. Deb Muth 03:15And while it’s not quite that simple, the reality is actually more sophisticated and honestly more beautiful. Stem cells are powerful and they absolutely work, but the way they work and the mechanism by which they support healing is far more elegant and more so than most people really understand. And if you’re going to invest in regenerative therapy, you deserve to understand what you’re actually receiving. Dr. Deb Muth 03:44So, let’s start at the beginning. What are stem cells? At their core, stem cells are undifferentiated cells. That means they haven’t yet decided what they want to be when they grow up. Unlike a heart cell or a skin cell or a bone cell which have already committed to a specific function, stem cells exist in this beautiful state of potential. Dr. Deb Muth 04:05They have two remarkable abilities. First, they can self-renew. They can make copies of themselves, maintaining a reserve of these powerful cells throughout your lifetime. Second, they can differentiate under the right conditions. They can transform into specialized cell types. Bone cells, cartilage cells, nerve cells, muscle cells, even blood cells. Dr. Deb Muth 04:27This is why they’ve captured the imagination of the medical world. The potential is extraordinary. Now, there are several types of stem cells and understanding the differences matters tremendously for both understanding how they work and understanding how they’re regulated. Adult mezzenymal stem cells. We call these MSC’s are the most commonly used regenerative medicine. Dr. Deb Muth 04:54These come from bone marrow, atapost tissue, that’s fat, and other adult sources. They’re what we can call multi-potent, meaning they can become several types of cells, but not every type. A bone marrow stem cell isn’t going to become a brain cell, for instance. It has potential but it’s directed potential. Dr. Deb Muth 05:19Then we have perinatal stem cells. These come from umbilical cord blood cord tissue or something called Wharton’s jelly which is the gelatinous substance inside the umbilical cord. These cells are younger, more potent, and research by Weiss and colleagues published in stem cells back in 2006 showed that Wharton’s jelly derived MSC’s have superior proliferation and differentiation potential compared to bone marrow derived cells. Dr. Deb Muth 05:48They’re like comparing a 20-year-old athlete to a 50-year-old athlete. Both can perform, but one has more reserve capacity, more vigor, and more regenerative potential. And this isn’t this is very important because the perinatal sources umbilical cord tissue Wharton’s jelly amniotic tissue these are what many regenerative medicine clinics in the United States are using today and they’re using them because these tissues are incredibly rich in not just stem cells but growth factors cytoines and exoomes. Dr. Deb Muth 06:21Then there are embryionic stem cells. These are pur potent and they become any cell type in the body, but they’re highly regulated, ethically controversial, and honestly, they’re not being used in clinical practice in the United States outside of the very specific FDA approved research trials. Dr. Deb Muth 06:41So, when clinics talk about stem cell therapy, they’re almost never talking about embryionic stem cells. Now, here’s where it gets interesting and this is the part that changes everything about how we understand regenerative medicine. When you receive stem cell therapy, let’s say someone injects umbilical cord derived messenymal stem cells into your arthritic knee, those cells do not typically engraft or become new tissue in any permanent way. Dr. Deb Muth 07:12They don’t set up shop in your joint and start cracking out new cartilage cells for the rest of your life. So what are they actually doing then? Well, in 2011, researchers Arnold Arnold Kaplan and Dennis Korea published a landmark paper in stem cells translational medicine that fundamentally changed how we understand MSC therapy. Dr. Deb Muth 07:35They proposed that we should stop calling memal stem cells and start calling them medicinal signaling cells. Why? Well, because their primary therapeutic benefit doesn’t come from what they become. It comes from what they secrete. Think of stem cells as incredibly sophisticated biological pharmacies. When you inject them into damaged tissue, that arthritic knee, that inflamed autoimmune condition, that injured brain, that don’t just sit there passively, they sense the environment. Dr. Deb Muth 08:07They detect inflammation. They recognize the tissue damage and they understand that the immune dysregulation is present and they see that and respond. They start pumping out hundreds of bioactive molecules, growth factors that tell your cells to repair and rebuild, cytoines that modulate inflammation, chemocines that recruit your body’s own healing cells to the area. Dr. Deb Muth 08:32And these tiny membranes bound packages called extracellular vesicles, including exosomes, which we’re going to talk about extensively today as well. These secreted factors are giving instructions to your native cells. They’re saying, “Let’s reduce inflammation. Let’s modulate your immune response. Let’s promote angioenesis. Dr. Deb Muth 08:53” That’s the formation of new blood vessels, bringing nutrients and oxygen. Let’s stimulate your own resident stem cells to wake up and get to work. Reduce cell death in damaged tissue and restore normal cellular function. This is called paracrine signaling. It’s the cellto cell communication. And this is where the real therapeutic power lives. Dr. Deb Muth 09:14The stem cells themselves, many of them die within days to weeks, but the cascade of healing they trigger, the signals they send, the programs they activate in your own cells, those effects can last for months or even years. Now, this understanding is crucial because it explains why both stem cell therapy and exoo therapy can be effective. Dr. Deb Muth 09:38The stem cells are powerful not because they become new tissue but because of the signals they send and exoomes are those signals isolated and concentrated. The biggest misconception in regenerative medicine is that stem cells replace tissue and in reality they coach healing more than they become healing. They’re biological educators teaching your body to remember how it used to heal before chronic inflammation, toxicity, and disease turned off all those programs. Dr. Deb Muth 10:12So if stem cells don’t exactly end graft and become the new tissue, if their power is in their signaling and then next logical question is why do we need the cells at all? Well, if we could isolate the messengers themselves, what if we could deliver just the communication systems without any of the complexity of the living cells? Well, that’s exactly what exosomes are. Dr. Deb Muth 10:38And they represent the cutting edge of regenerative medicine. So, let me paint you a picture of how cells actually communicate. Because for most medical history, we had it wrong. For decades, textbooks taught us that cells talk to each other in two basic ways. through direct contact like shaking hands or releasing signaling molecules that floated through the extracellular space like messages in bottles, simple chemical messages. Dr. Deb Muth 11:09But in the 1980s and 90s, researchers started discovering something far more sophisticated. cells were releasing these tiny membrane bound packages like a biological FedEx envelope kind of you know it was filled with complex specific cargo and these packages could travel through the blood cross the barriers that normally keep things out like bloodb brain barrier and deliver their contents to distant cells with remarkable precision. Dr. Deb Muth 11:38These are called extracellular vesicles. And exoomes are one of the most therapeutic important types. So what exactly are exosomes? Well, they’re nanosized vesicles, typically 30 to 150 nanome in diameter. To put that into perspective, a human hair is about 100,000 nanometers wide. These are incredible and most impossibly tiny. Dr. Deb Muth 12:09They’re released by virtually all cells in the body, but the most therapeutically interesting exoomes come from mezenymal stem cells. And those medicinal signaling cells we just discussed. And according to a landmark review of Raposo and Stervogal, they published in the journal of cell biology in 2013, exoomes are not cellular debris. They’re not waste products. Dr. Deb Muth 12:35They are precisely engineered communication vesicles or vehicles. Think of them as sophisticated delivery systems carefully packed, carefully labeled, and sent to specific destinations. very specific instructions. Inside each of these exoomes, you’ll find an incredibly sophisticated payload. They are microRNAs. These are small RNA molecules that can literally turn genes off or on in the recipient cells. Dr. Deb Muth 13:06They can tell a cell to start making more collagen, to reduce inflammatory proteins, to activate repair programs that have been shut down by chronic disease for a very long time. There are messenger RNAs, actual templates for protein production. And exoome can deliver these instructions for making healing proteins. There are proteins themselves, growth factors, cytoines, enzymes, all the molecular tools a cell needs to heal. Dr. Deb Muth 13:34And there are lipids, specialized fats that help the exoome membrane fuse with targeted cells, delivering the cargo inside. When an exoome reaches its target cell, it can either fuse the cell membrane and deliver its contents directly inside like a Trojan horse, or it can bind to surface receptors and trigger signaling cascades, setting off a chain reaction of healing responses. Dr. Deb Muth 14:01Either way, it’s delivering very specific targeted instruction. And here’s what makes this so powerful. Those instructions are tailored to what this recipient cell actually needs. So, let me give you some concrete examples of what the research actually shows because this is where it really gets exciting. When researchers inject MSC derived exoomes into hearts that had experienced eskeeia, reprofusion, injury, that’s damaged blood flow being cut off and then being restored. Dr. Deb Muth 14:36Kind of like what happens during a heart attack. Something remarkable happened. A study by Lei and colleagues published in stem cell research in 2010 showed that exoomes significantly reduced the size of the damaged area, reduced inflammatory cytoines that drive tissue destruction and promoted tissue repair signaling. The exoomes were telling the heart cells stop the inflammatory cascade, activate your survival programs and repair the damage. Dr. Deb Muth 15:06In cartilage research, tow and colleagues published work in biioaterials in 2017 showing that exosomes derived from MSC’s could promote cartilage regeneration in osteoarthritis models. And the exoomes carried specific microRNAs that told condondroytes cartilage cells to proliferate and make more extracellular matrix, the structural framework of healthy cartilage. Dr. Deb Muth 15:30for autoimmune conditions. Research by Blazic and colleagues in Frontiers in Immunology in 2014 demonstrated that MSC derived exoomes could shift immune cell behavior from pro pro-inflammatory to regulatory. They could take an overactive self-attacking immune system and restore balance and promote tolerance. And perhaps most exciting brain research, a study by Zinn and colleagues published in the journal of extracellular vesicles in 2013 showed that MSC derived exoomes could cross the bloodb brain barrier. Dr. Deb Muth 16:07That protective shield around your brain that normally keep things out and promote neurological recovery in stroke models. They reduced brain inflammation, promoted neuroplasticity, supported the formation of neural connections, and for mitochondrial dysfunction, which underlies so many chronic conditions, Morrison and colleagues published research and scientific reports in 2017 showing that MSC derived exoomes can actually deliver functional mitochondria or mitochondrial components to damaged cells. They’re not Dr. Deb Muth 16:40just sending instructions, they’re sending spare parts. They’re restoring the cellular powerhouses to produce energy. So why are exoomes fundamentally different from stem cells? Well, exoomes contain no living cells. They can’t replicate. They can’t end graph. And they have virtually no risk of immune rejection or tumor formation. Dr. Deb Muth 17:03Concerns that exist elevate rarely with cellular therapies. They’re essentially biological software updates for your cells. As Fineian Pitiger wrote in their seinal review in stem cells in 2017, MSC derived exoomes represent the active ingredient of stem cell therapy delivered in a cellfree format. That’s the key insight in the in the therapeutic benefit of stem cells and it comes from what they excrete. Dr. Deb Muth 17:33Then exoomes are the secretion isolated, concentrated, and standardized. From a practical clinical standpoint, exoomes offer several compelling advantages. First, consistency. Because exoomes can be isolated, characterized, and standardized, each dose can be remarkably consistent. With living stem cells, there’s variability based on donor age, health status, processing methods, and one batch may be robust, but another might be weaker. Dr. Deb Muth 18:05With exoomes, you can measure the content, measure the potency, and ensure the quality control. Second is storage. Exoomes can be liophalized. They can be freeze-dried and stored at room temperature or refrigerated for extended periods. Stem cells require cryopreserv preservation, careful freezing, careful thawing. They’re fragile. Dr. Deb Muth 18:31Exoomes are remarkably stable. And third, their safety profile. Without living cells, the risk of adverse imunological reactions is dramatically lower. You’re not introducing foreign cells that your immune system might recognize and attack. You’re introducing molecular messages. Fourth is scalability. You can harvest millions, even billions of exoomes from stem cell cultures without ever injecting the cells themselves. Dr. Deb Muth 19:01And you can produce large quantities, standardize them, and make them available to patients. Now, there is a caution here in doing this. The scalability can produce rogue cells, and we want to be cautious of that. So, here’s what I need you to understand. Exoomes don’t force healing. They remind the body how healing works. Dr. Deb Muth 19:24They’re not replacing damaged cells. They’re re-educating the cells you already have. They’re turning back time on the biological programs that got turned off by inflammation, toxicity, trauma, time, and chronic disease. Your body knows how to heal. It’s done its entire life. Every cut that closed, every bone that mended, every infection you fought off, your body orchestrated that healing. Dr. Deb Muth 19:51The problem is that chronic disease, chronic inflammation, toxic exposures, poor nutrition, stress, all of these things disrupt the communication networks that coordinate healing. And exoomes restore that communication. They’re like rebooting a computer that’s frozen. They reset the system and remind it how it’s supposed to function. All right. Dr. Deb Muth 20:14So, this would not be complete if we didn’t talk about regulation because this is where a lot of confusion exists. And I want you to be given a real picture. Not fear-mongering, not pretending. There aren’t regulatory considerations, but the actual practical reality of how regenerative medicine is practiced in the United States today. Dr. Deb Muth 20:38Here’s what you need to understand. The FDA regulates these therapies and they have specific frameworks, but there’s important nuances between regulatory text enforcement priorities and actual clinical practice. And there are also state level regulations that provide additional pathways. The FDA regulates human cells, tissues, and cellular and tissue based products. Dr. Deb Muth 21:05We call them HCT/PPS under two main pathways. Section 361 products are those that meet specific criteria. They’re minimally manipulated, intended for homologous use, meaning these tissues perform the same basic function in the recipient as it did in the donor. They’re not combined with non-tissue components and they’re either autotogus, meaning they come from your own tissue, or they have had minimal systemic effect. Dr. Deb Muth 21:38An example of a clear 361 procedure, your doctor harvests your own bone marrow, we call this PRP, performs minimally processing to or uh perform Yeah. performs minimal processing to concentrate the stem cells through a centriuge and injects it into your arthritic knee the same day. That’s autogus same day but minimally manipulated. Dr. Deb Muth 22:04This is unquestionably legal and is being done in regenerative medicine clinics across the country every single day. So there’s section 351 where products are those that don’t meet all the section 361 criteria. They’re classified as drugs or biologic products and they require FDA approval through clinical trials. Dr. Deb Muth 22:27Now here’s where this gets more nuanced. There are regenerative medicine clinics across the United States using stem cell and exoome therapies in different contexts. First FDA registered clinical trials. These are formal research studies with investigational new drug applications. Patients enroll in trials. They sign informed consents. Dr. Deb Muth 22:48They receive therapies as part of their structured research protocols. And this is completely legal and represents the gold standard for gathering evidence. Second is observational studies and registry programs. Many clinics are collecting systemic data on patient outcomes using these therapies even outside the FDA trials. Dr. Deb Muth 23:12They’re documenting results, tracking safety, and contributing to the growing body of clinical evidence. Third, there’s clinical practice under physician discretion. There are physicians using these therapies based on their own clinical judgment informed consent from patients and their interpretation of the regulatory framework particularly around minimal manipulation and homologous use. Dr. Deb Muth 23:34Now there are also state regulations that provide additional legal frameworks. So, for example, Florida has enacted the Right to Try Act and specific regenerative medicine legislation that allows physicians to offer certain stem cell therapies under the state oversight. Utah has passed similar legislation creating pathways for regenerative medicine products. Dr. Deb Muth 23:57And these state laws recognize that patients should have access to potentially beneficial therapies, particularly when used by trained physicians with appropriate informed consent. The regulatory question often centers around are these products minimally manipulated. Some products clearly are not. They’ve been cultured. Dr. Deb Muth 24:20They’ve been expanded in laboratories and those require FDA approval that they don’t have. The FDA has appropriately shut down clinics using those products. But there are other products that undergo processing that many physicians and manufacturers argue constitutes minimal manipulation. And these tissues are cleared, potentially fragmented or particulated to make them more suitable for injection, preserved using methods like cryopreservation or liophalization and packaged. Dr. Deb Muth 24:54But the cells are not cultured or expanded in the laboratory. The FDA has issued guidance suggesting that many of these processing steps constitute more than manipul minimal manipulation. But many physicians, particularly those who specialized in regenerative medicine for years, disagree with that interpretation and they believe that the processing qualifies as minimal manipulation and that the product should fall under section 361 when used for homologous purposes. Dr. Deb Muth 25:24Is there regulatory debate? Absolutely. The FDA and some clinicians have different interpretations of what constitutes minimal manipulation. But here’s the practical reality. There are hundreds of well-trained, bore certified physicians across the United States offering these therapies every single day. Dr. Deb Muth 25:42They’re doing so based on their understanding of the regulations, their clinical experience, their commitment to patient safety, and their belief that these therapies can help people who have exhausted conventional options. The FDA’s enforcement priorities have focused primarily on the most problematic cases. Clin clinics making blatant disease cure claims, products with documented safety issues, clear cases of cellular expansion and culture, or clinics operating with no medical oversight. Dr. Deb Muth 26:15Reputable regenerative medicine physicians are using products from companies that provide comprehensive documentation of their processing methods. third-party sterility testing, certificates of analysis showing bioactive content, and quality control measures that meet or exceed industry standards. Now, let me be very clear about something. Dr. Deb Muth 26:36Quality matters enormously. Not all stem cells and exoome products are created equal. Research by Burger and colleagues published in the Orthopedic Journal of Sports Medicine in 2021 analyzed 12 commercially available stem cell products and found that many contained zero viable cells, high levels of bacteria, endotoxins and inconsistent growth factor concentrations. Dr. Deb Muth 27:01This is why the company providing these biologic matters tremendously. You want products from manufacturers who provide transport documentation in sourcing and processing. Conduct third-party testing and sterility and potency. Offer certificates of analysis for each batch. Use standardized validated processing protocols. Dr. Deb Muth 27:24Have quality control measures that ensure consistency and don’t make outrageous cure claims or promise. The best regenerative medicine physician carefully vet their suppliers. They don’t use products from companies making unrealistic promises. They use products from manufacturers who are transparent, scientifically rigorous, and committed to quality. Dr. Deb Muth 27:46Now, you specifically ask about homologous use and collagen defects. So, let me address this directly for you. Under the FDA guidance, homologous use means the tissue performs the same basic function in the recipient as in the donor. So for connective tissue, tendons, ligaments, cartilage, fascia, all of that which are collagenrich structures using MSC’s or their derivatives could be considered homologous use. Dr. Deb Muth 28:17MSC’s in their native environment provide structural support to produce extracellular matrix including collagen. Using them to support healing in damaged collagen rich tissues like arthritic joints, torn tendons or degenerative ligaments is arguably the same basic function. So using exoomes derived from MSC’s to support collagen synthesis reduce inflammation and promote tissue healing in the same structures. Dr. Deb Muth 28:46Many practitioners argue this also qualifies as homologous use because you’re supporting the structure and function that MSC’s would naturally support. So here’s the bottom line on the regulatory reality. Regenerative medicine is available in the United States. It’s being offered by highly trained physicians in integrative and regenerative medicine clinics across the country. Dr. Deb Muth 29:11Some therapies are offered in FDA registered clinics and some are offered in observational studies. Some are offered in clinical practice under physician discretion, informed consent, and careful attention to safety. The regulatory landscape is evolving. There are ongoing discussions both federally and state levels about creating clearer pathways for these therapies. Dr. Deb Muth 29:32So, if you choose to go down this road, you want to work with physicians who understand the regulations, who use quality products from reputable manufacturers with rigorous testing and documentation, who are transparent about what they’re using and why, who discuss the current regulatory landscape honestly with you, and who prioritize your safety and truly informed consent above all else. Dr. Deb Muth 29:55This is not a lawless wild wild west. But it is also not as simple as everything is legal and unavailable. It’s a nuanced landscape that requires ethical knowledge. And these practitioners that have this knowledge have got to provide informed patients who understand both the potential benefits and the current regulatory context. Dr. Deb Muth 30:17So let’s have some fun here. Let’s talk about what really matters to you that are listening and that’s what conditions are being supported with these therapies. What does the research show and what are clinicians seeing in actual practice with patients? Because here’s what’s really important. We have both published research evidence and extensive clinical experience. Dr. Deb Muth 30:38And when the two align, that’s when we can feel confident and comfortable about using these approaches. So, let’s start where we have the most substantial evidence. joint health and muscularkeeletal conditions. For arthritis, we have good data. A systemic review by Tan and colleagues published in arthritis research and therapy in 2021 analyzed 20 randomized controlled trials in MSC therapy for knee osteoarthritis. Dr. Deb Muth 31:05They found significant improvements in pain and function particularly in mild to moderate disease. What’s really interesting is when researchers start analyzing whether it was the cells themselves or their secreted factors doing the work. They found that exoomeenriched preparations showed similar benefits to whole cell therapy. Dr. Deb Muth 31:26Now towen colleagues in the biioaterials paper from 2017 demonstrated that MSC derived exoomes could promote cartilage matrix synthesize and reduce inflammation markers. The exoomes carried microarnas that told cartilage cells to make more collagen and proteoglycans, the building blocks of healthy cartilage. Dr. Deb Muth 31:49In clinical practice, physicians are seeing patients with knee, hip, shoulder, and spinal arthritis, experiencing reduced pain, improved function, better motility, and in some cases, measurable improvements in their tissue. I want to share a story here with you because back in 2006, my husband was injured at work. Some of you might have heard me tell this story before. Dr. Deb Muth 32:11Um, he broke two discs in his back and underwent surgery very early on when we started using stem cells. They had put cages and plates in and they used MSC’s to put inside the cage to create a hardened bone so that he could have a fusion and hopefully not have any pain. At the time, what the physician didn’t realize or mistakenly did was he did not put any human bone mixed with these dead cadaavver bone MSC’s. Dr. Deb Muth 32:42And so the MSC’s never grew. They didn’t have anything to grow by. So the plates and the screws just kind of went back and forth for six months before he could see another physician that would look at him differently and understand what actually happened. That was very early on. Today we know so much more than we did before. Dr. Deb Muth 33:01Fast forward to 2014 when my husband was having problems and he couldn’t feel his legs, he couldn’t feel his feet. We decided to undergo uh exoo and stem cell therapy again and we saw a physician in Florida who harvested cells from his bone marrow and his blood and his fat and mixed that all together and then put that back into the back. Dr. Deb Muth 33:27and he had tremendous benefit from it. So, I tell this story because I want you to see the trajectory of how long this has been going on that we’ve been using this and we’re learning as we’re going and things are changing rapidly in this in this world. And so, what we know today and what I’m teaching you today may very well change in a month or six months or a year from now, but we have the foundation at least to understand what is helpful, what is not right now. Dr. Deb Muth 33:54But just be aware that if you’re embarking on exoome or stem cell therapy or MSC’s that you understand that this terrain is going to change. So back to my conversation about what other things can we treat? Well, we can treat tendon and ligament injuries, chronic tennis elbow, Achilles tendonopathy, rotator cuff tears, chronic planter fasciitis. Dr. Deb Muth 34:17These were researched by PA and colleagues in the American Journal of Sports Medicine in 2017 and it showed that bone marrow concentrate injections resulted in improved pain and function compared to steroid injections. Now this mechanism appears to be enhanced collagen remodeling and reduced chronic inflammation. Dr. Deb Muth 34:39These are structural collagenrich tissues using MSC’s or their derivatives for structural support which makes biological sense. It’s homologous use. It’s similar. So clinically we’re seeing athletes, active adults and people with chronic pain who failed physically um failed physical therapy, failed conservative treatments finding relief in this functional uh improvement in this functional world that we live in today. Dr. Deb Muth 35:07So, I want to be clear about what we’re doing here for joint and muscularkeeletal issues. We’re not growing completely new cartilage from scratch or severely destroyed joints. We’re not magically regenerating tissues that’s been gone for decades. That’s not possible here. What you’re doing when you’re using MSSE’s and exoomes is supporting the body’s natural ability to repair, reducing inflam inflammation and damage, and we’re driving progressive degeneration uh or we’re stopping the progressive degeneration. By reducing the Dr. Deb Muth 35:41inflammatory damage, we’re stimulating resonant stem cells that have been dormant. We’re improving blood flow and uh uh oxygen to the tissues like cartilage and tendons. and we’re organizing the body to start creating its own quality collagen as it heals. So, it’s a regenerative support, not a tissue replacement. Dr. Deb Muth 36:07But for many people, this support is lifechanging. So, let’s talk about autoimmune disorders now because this is one of the most exciting and unrecognized applications. autoimmune conditions like rheumatoid arthritis, lupus, MS, Crohn’s disease, ulcerative colitis, Hashimoto’s, they all involve the immune system and the immune system is deregulated. Dr. Deb Muth 36:30And so basically your immune system is seeing this tissue as foreign and it’s attacking it. These MSC’s and their exoomes have profound immune modulatory properties. They don’t suppress the immune system like steroids or imunosuppressive drugs. They modulate it helping to restore balance. So for rheumatoid arthritis, research by Weang and colleagues in stem cells translational medicine in 2016 showed that MSC derived exoomes could shift the balance of immune cells, reducing pro-inflammatory TH7 cells that drive joint disruption uh and increase Dr. Deb Muth 37:08regulatory TE-C cells that maintain immune tolerance. So for MS, a clinical trial by Kasus and colleagues published in archives of neurology back in 2010 evaluated autotogus MSC therapy and MS patients and they found evidence of reduced disease activity, improved neurological function and decreased inflammatory uh lesions on MRI scans. Dr. Deb Muth 37:34The proposed mechanism is MSC’s and their exoomes reduce inflammatory cytoine production promote regulatory imu immune populations support remination of damaged nerves that is rebuilding the protective coating around the nerve fibers and it reduces bloodb brain barrier permeability which prevents immune cells from attacking their brain and spinal cord. Dr. Deb Muth 38:02And so for inflammatory bowel disease, the research by Barnholm uh sorry Barnhorn and colleagues in gut in 2020 showed that MS cell MSC derived extracellular vesicles could support mucosal healing and reduce inflammation in the gut lining. They appeared to restore intestinal barrier function, healing that leaky gut and modulating local immune responses. Dr. Deb Muth 38:30So in clinical practice, physicians are seeing patients with autoimmune conditions, experiencing reduced disease flares, decreasing the need for imunosuppressive medications, improving energy and quality of life, and in some cases extending periods of remission. But here’s what I want you to understand. Dr. Deb Muth 38:52When you see these therapies for autoimmune conditions, we are supporting immune regulation and reducing inflammatory damage. We are not treating or curing the disease in a conventional sense. These therapies work best as part of a comprehensive functional medicine approach that also addresses gut health because 70% of your immune system lives in your gut and environmental triggers like mold, heavy metals, chemical toxins that can drive autoimmune responses, chronic infections that can trigger immune disregulation, stress and nervous system imbalance. And Dr. Deb Muth 39:29these nutritional deficiencies are necessary to help improve the immune function. So regenerative therapy without addressing root causes is like bailing water out of your boat without plugging the hole. You might get temporary relief, but the underlying problem still remains. So let’s talk about neurological conditions. Dr. Deb Muth 39:52And this is where the science gets truly fascinating. for traumatic brain injury and concussion. Research by Zang and colleagues in the Journal of Neurot Trauma in 2015 showed that MSC derived exoomes could reduce brain inflammation, promote neuroplasticity, that’s the brain’s ability to rewire itself and improve cognitive outcomes in animal models. Dr. Deb Muth 40:17The exoomes crossed the bloodb brain barrier, delivered neuroprotective proteins and microRNAs. They reduced inflammation, supported mitochondrial function in injured neurons and promoted both new blood vessels from new blood formation and neurogenesis and the birth of new neurons occurred. Neurological recovery requires a multi-systematic approach. Dr. Deb Muth 40:42Exoomes may support neural repair, but they work best combined with hormone optimization, growth hormone, testosterone, thyroid, pregnnolone, mitochondrial support compounds like NAD, CoQ10, PQQ, carnitine, all of those things that we use traditionally in functional medicine. Now for stroke recovery, there was research by Zinn and colleagues in the journal of extracellular vesicles that showed MSC derived exoomes reduced the size of brain damage and improved neurological recovery in animal models. There was a Dr. Deb Muth 41:19Parkinson’s disease study done by Kimoji and colleagues in the movement disorders in 2018 that suggested that MSSE derived exoomes could support dopamineergic neuron survival and those are the cells that die in Parkinson’s and it can help to reduce neuroinflammation. Clinically, physicians are seeing improvements in patients with postconussion syndrome, chronic traumatic brain injury, early stage cognitive decline, and other neurodeenerative conditions. Dr. Deb Muth 41:52These are not cures, but meaningful improvements in cognitive function, mood, energy, and quality of life. Now, let’s talk about autism spectrum disorder very carefully here because this is a very sensitive but very important topic for families. There have been several clinical trials that have explored MSC therapy for autism. Dr. Deb Muth 42:16Liv and colleagues published research in stem cell translational medicine in 2013 showing improvements in social interaction, communication, and behavioral symptoms in children with ASD who received cord blood MSC’s. Dawson and colleagues in 2017 conducted randomized trial autotogus cord blood infusion and found modest improvements in social communication particularly in children with higher baseline immune dysregulation. Dr. Deb Muth 42:47The proposed mechanisms for modulation of neuroinflammation support the mitochondrial function because many children with autism show evidence of mitochondrial dysfunction, reduction of oxidative stress, improvement in gut brain access dysfunction and modulation of immune dysregulation. In clinical practice, some physicians are seeing improvements in some children, better eye contact, increased language development, reduced sensory sensitivities, improved social engagement, but responses vary significantly, and we cannot predict which children will benefit most. So for Dr. Deb Muth 43:26families considering regenerative approaches for autism, these therapies are supporting the body’s healing mechanisms, reducing neuroinflammation, supporting cellular energy production, modulating immune function. These should only be considered as part of a comprehensive biomedical approach that includes dietary interventions to address food sensitivities, support gut health, environmental toxin removal, particularly heavy metals and chemical exposures, gut healing protocols with targeted probiotics and nutrients, Dr. Deb Muth 44:00metabolic testing and targeted supplementation, and evidence-based on behavioral and developmental therapies. These therapies should only be pursued with practitioners who are honest about what we know and what we don’t know and who follow rigorous safety protocols who never promise cures and who view regenerative medicine as a tool in the comprehensive healing strategy, not a standalone miracle. Dr. Deb Muth 44:26Not only that, these therapies will most likely need to be given several times over the course of this person’s lifetime, possibly even on an annual basis. And this is really important because it is not a oneandone. It is not a one-sizefits-all, and it needs to be looked at as a long-term option for working with autism. So, since we’re looking at stem cells versus exoomes, living cells, with stem cell therapy, you’re receiving living cells that can survive in your body for days to weeks. Dr. Deb Muth 45:02With exoome therapy, there are no living cells, just biological messages they would have sent. So, replication stem cells can potentially replicate. Although therapeutically this happens minimally, exoomes cannot replicate. They deliver the cargo and then they are cleared by your body. With stem cells, it’s primarily paracrine signaling. Dr. Deb Muth 45:28They’re coaching your cells to heal. With exoomes, it’s pure signaling, pure reprogramming your cells without any cellular component. Stem cells as we talked about can be autotogus from your own bone fat, blood or um bone marrow or allergenic from umbilical cord tissue or Wharton’s jelly. Dr. Deb Muth 45:50Exoomes are typically derived from cultured MSC’s often from umbilical cord or bone marrow sources and both can be given by local injection for targeted treatment of joints and tissues and exoomes can be given intravenously for whole body systemic support. both have um low immun immunogicity. I can’t say that word today. Dr. Deb Muth 46:17But exoomes have even lower risk since they contain no cellular material. Now, it’s absolutely critical for you to understand that there are massive quality differences. We’ve talked about this earlier. I want you to be very aware of this and have a conversation with any of the practitioners that you’re considering undergoing this treatment with. Dr. Deb Muth 46:37Here is where it matters more than anything when you’re considering regenerative medicine, the quality of the products and the expertise of the practitioner. Because the reality is not all regenerative medicine products are created equal. We all know that when we take different supplements and not all practitioners understand these therapies at the same depth. Dr. Deb Muth 46:58You want to look for practitioners that are board certified or have some kind of specialized regenerative medicine training. You want to know their clinical experience. How much have they done these procedures? How long have they done this? You want honest communication about the evidence and the limitations in this. Dr. Deb Muth 47:17You want a comprehensive functional medicine approach to go along with these therapies. And you want somebody that’s transparent about their informed consent and their regulatory status. If you have people that are uh claiming that they can cure disease or giving you guarantees, that is not that is not a good practitioner to work with. Dr. Deb Muth 47:37If you have high pressure sales tactics, you need to decide today limited supply for a week. These are marketing manipulations. It’s not medical care. You want to be cautious of extremely low prices because quality regenerative products are expensive to source, process, and test. and store. And if somebody’s offering stem cells or exoomes for a few hundred dollars, seriously, you need to question the quality, the safety, and where they got this from. Dr. Deb Muth 48:09So before undergoing any regenerative therapy, make sure you’re having a very, very lengthy conversation with the person and so you truly understand exactly what you’re getting, how it’s going to be delivered, and what they’re going to do. If there’s one thing I want you to take away from today is that your body has remarkable capacity to heal when given the right biological signals and the right environment. Dr. Deb Muth 48:35Stem cells and exoomes are powerful tools for providing biological signaling that can reduce inflammation, modulate immune function, support tissue repair, and restore cellular communication that’s been disrupted by chronic disease and inflammation. These therapies are available in the United States through trained physicians working in FDA registered trials, observational studies, and clinical practice, and using quality products from manufacturers with rigorous testing and quality control. Dr. Deb Muth 49:04So before you invest in regenerative medicine, do your homework. Ask detailed questions about product quality and source. Verify the products come from reputable manufacturers with certificates of analysis, third-party testing. Work with experienced practitioners. And remember, no injection, no infusion, no biologic can overcome ongoing toxic exposure, chronic stress, poor nutrition, gut dysfunction, and inadequate sleep. Dr. Deb Muth 49:34True healing requires your body and you to actively participate in this healing. If you are unwilling to address the root causes and change the lifestyle factors that disrupted your health in the first place, the biologics can amplify your healing signals, but you have to create the internal environment where healing can actually happen. Dr. Deb Muth 49:56So, I hope this episode has helped you understand regenerative medicine more clearly. Share it with somebody who’s looking for healing beyond the conventional approaches. And until next time, this has been Let’s Talk Wellness Now. Have a blessed day. >> Welcome to Let’s Talk Wellness Now, where we bring expert insights directly to you. Dr. Deb Muth 50:16Please note that the views and information shared by our guests are their own and do not necessarily reflect those of Let’s Talk Wellness Now, its management, or our partners. Each affiliate, sponsor, and partner is an independent entity with its own perspectives. Today’s content is provided forformational and educational purposes only and should not be considered specific advice, whether financial, medical, or legal. Dr. Deb Muth 50:41While we strive to present accurate and useful information, we cannot guarantee its completeness or relevance to your unique circumstances. We encourage you to consult with a qualified professional to address your individual needs. Your use of information from this broadcast is entirely at your own risk. Dr. Deb Muth 51:00By continuing to listen, you agree to indemnify and hold Let’s Talk Wellness Now and its associates harmless from any claims or damages arising from the use of this content. We may update this disclaimer at any time, and changes will take effect immediately upon posting or broadcast. Thank you for tuning in. We hope you find this episode both insightful and thought-provoking. Listener discretion is advised.The post Episode 265 – The Future of Healing: How Exosomes Re-Educate Your Body to Heal Itself first appeared on Let's Talk Wellness Now.

There are many outstanding leaders in the sports medicine and musculoskeletal rehabilitation world. How did they get there? What decisions did they make that have got them to where they are today? In today's episode, Dr Amber Donaldson shares what she is looking for in the next generation of sports medicine leaders, how she has approached developing her own career, and her advice for early-career clinicians looking to establish themselves in elite sports medicine. Dr Donaldson is the Vice President - Sports Medicine at the United States Olympic and Paralympic Committee.

Bizeps-Curls schlagen Kurzhantel-Rudern beim Muskelwachstum – mit 11 Prozent gegen 5 Prozent. Eine Zahl aus dem Journal of Strength and Conditioning Research, die so ziemlich allem widerspricht, was Du in den vergangenen zehn Jahren über „echtes“ Krafttraining gehört hast.In dieser Folge räumt Mark mit einem der hartnäckigsten Dogmen der Fitness-Welt auf und zeigt Dir, warum reine Grundübungen Dich auf einem Plateau festkleben lassen können – und was Du stattdessen tun solltest. Du erfährst: Was die aktuelle Studienlage WIRKLICH zum Vergleich Grundübung vs. Isolation sagt – mit drei Ergebnissen, die selbst erfahrene Trainierende überraschen Wie die Wissenschaft zeigt, dass richtiges Krafttraining altersbedingte Muskelveränderungen nicht nur stoppt – sondern umkehrt Die Tischler-Formel: Wann Du den Hobel benötigst, wann Du zum Schleifpapier greifen solltest Die 80/20-Regel für effektives Krafttraining – und warum sie für die Ü40-Crew besonders wertvoll ist Drei Quick-Wins, die Du sofort umsetzen kannst Viel Spaß beim Reinhören!____________*WERBUNG: Infos zum Werbepartner dieser Folge und allen weiteren Werbepartnern findest Du hier.____________

Listen to our latest podcast as we break down our favorite orthopedic surgery and sports medicine movie movements from films such as Trainwreck, The Dark Knight Rises, Friday Night Lights, and Rookie of the Year (and more!)

In this episode, Eric welcomes Dr. Robby Sikka, who brings a wealth of sports medicine research experience across a variety of sports. Robby shares insights about the dramatic rise in injuries in professional tennis while also speaking to the broader landscape of sports medicine trends across high level sports.

Urolithin A (MitoPure)--Mitophagy, Muscle Recovery, Immunity, and Skin Health: Dr. Brad Currier, clinical trial manager at Timeline, a Swiss biotech company, details urolithin A (MitoPure), a postbiotic derived from pomegranate precursors that most people cannot produce due to microbiome differences. Currier explains MitoPure's mechanism—stimulating mitophagy to recycle dysfunctional mitochondria—and reviews evidence from multiple clinical trials. He reveals a Sports Medicine study in elite male distance runners showing reduced creatine kinase and lower perceived exertion, suggesting improved recovery, plus trials in middle-aged and older adults showing improvements in strength, six-minute walk test, and VO2 max at 500 mg–1 g doses. They also cover a Nature Aging immune study reporting rejuvenation of stem-like CD8 T cells with improved mitochondrial fatty acid oxidation, ongoing research directions, supplement quality/testing for athletes, and topical urolithin A skincare trials and partnerships, including L'Oréal Lancôme.

Dr. Courtney Conley holds a Doctorate in Chiropractic Medicine as well as two bachelor's degrees in Kinesiology and Human Biology. The founder and creator of Gait Happens, she has worked with professional athletic teams including the Phoenix Suns, New York Yankees, Cleveland Browns, New York Giants, San Francisco 49ers, and Minnesota Vikings. Dr. Conley is Head of Patient Care at Total Health Solutions and Total Health Performance, premier healthcare destinations renowned for their comprehensive and science-based approach to patient care. Dr. Milica McDowell holds two Bachelor of Science degrees (Exercise Physiology and Health Promotion, (Montana State University), a master's degree (Physical Therapy, University of Colorado Health Sciences Center), and a Doctorate degree (Physical Therapy, Idaho State University). She served as a university faculty member in Human Performance for nearly a decade, has developed numerous medical education curricula and has been an invited speaker on many national stages, including the American Physical Therapy Association and American College of Sports Medicine's conventions. Today on the show we discuss: why the 10,000 step rule is a myth rooted in marketing not science, how walking is a biological necessity that impacts your metabolism brain and mental health, why small “micro walks” can dramatically improve mood confidence and long-term consistency, the truth about fat loss and why walking works when you stack it with better sleep breathing and nutrition, how modern shoes are weakening your feet and what to do instead, and how to build a simple walking routine that actually improves longevity reduces depression and lowers your risk of disease and much more. Learn more about your ad choices. Visit megaphone.fm/adchoices