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On this episode of Inside Startup Investing, Chris Lustrino speaks with Dr. Michael Wyand, CEO of Oxeia Biopharma, a clinical-stage biotech company developing a potential breakthrough treatment for concussions and persistent concussion symptoms. Oxeia is leveraging ghrelin, a naturally occurring hormone involved in brain energy regulation and neural repair, to help heal the inflammation and cellular damage caused by traumatic brain injuries. With promising Phase 2a data showing an 85% responder rate among treated patients, the company is pursuing what could become the first FDA-approved pharmaceutical treatment specifically targeting concussion recovery. Chris and Michael discuss the science behind concussions, how brain damage occurs after impact, why “just rest” has remained the standard of care for decades, and how Oxeia's therapy could fundamentally change the treatment landscape for athletes, veterans, and millions of patients suffering from lingering neurological symptoms. They also dive into the company's clinical pathway, the business opportunity behind concussion therapeutics, the role of neurogenesis in recovery, and the broader future potential for treating conditions like CTE, Parkinson's disease, and ALS. If you want to understand the future of concussion recovery, brain health innovation, and biotech investing, this is an episode you won't want to miss.
Are your workouts actually building strength or just burning time? Amy Hudson and Dr. James Fisher break down the latest 2026 guidelines from the American College of Sports Medicine on how you should be training today. They unpack why consistency beats perfection, how minimal training can still deliver real results, and where most people waste time and effort. Tune in to simplify your approach and start training in a way that actually works.Dr. Fisher explains what the American College of Sports Medicine (ACSM) actually does. It's one of the main bodies shaping exercise science, from research journals to certifications that guide the industry.Dr. Fisher shares why resistance training is still massively underused. Around 60% of adults aren't doing any strength work, and only a small percentage hit the basic guideline of twice per week.Learn why consistency will always beat the “perfect program.” You don't need the smartest plan on paper if you're not showing up for it. What actually moves the needle is turning up regularly and putting in some effort, even on the days it feels basic.Amy covers how to choose a program you'll actually stick with. There's no shortage of “best” routines out there, but most of them fail because people don't follow through. The real win is picking something that fits your life so well that skipping it starts to feel uncomfortable.Dr. Fisher explains how to progress your training without overthinking it. If the weight, reps, or sets aren't gradually increasing, your body has no reason to adapt. Progress doesn't have to be dramatic, but it does need to be intentional.Amy covers why a personal trainer can quietly make all the difference. Most people fall into the habit of repeating the same weights and routines because it feels comfortable. A good personal trainer steps in to push progression just enough to keep you improving without burning out.Learn how working with a personal trainer improves more than just your results. You're not just getting guidance, you're also getting accountability, structure, and a reason to show up. That consistency alone is often what separates people who see change from those who stay stuck.Dr. Fisher explains why resistance training feels complicated (but isn't). Many people avoid it because they're unsure where to start or think it takes too much time. In reality, even two short 20-minute sessions a week can deliver meaningful results if done properly.Amy covers how to keep strength training simple and effective. Building strength is naturally repetitive. You don't need constant variety; you need consistency in doing what already works.Amy and Dr. Fisher agree that the basics will always outperform every “new hack.” Sleep well, eat decently, and challenge your muscles regularly is the foundation. Amy adds that it's easy to chase complexity, but most results come from doing simple things well over time.Dr. Fisher explains how eccentric overload can unlock more strength. Traditional weights give you the same resistance up and down, which limits how much you can challenge the muscle. With advanced tech like exerbotics devices, the lowering phase can match your strength more closely, creating a stronger stimulus and better results. Mentioned in This Episode:The Exercise Coach - Get 2 Free Sessions!Submit your questions at StrengthChangesEverything.com This podcast and blog are provided to you for entertainment and informational purposes only. By accessing either, you agree that neither constitute medical advice nor should they be substituted for professional medical advice or care. Use of this podcast or blog to treat any medical condition is strictly prohibited. Consult your physician for any medical condition you may be having. In no event will any podcast or blog hosts, guests, or contributors, Exercise Coach USA, LLC, Gymbot LLC, any subsidiaries or affiliates of same, or any of their respective directors, officers, employees, or agents, be responsible for any injury, loss, or damage to you or others due to any podcast or blog content.
In this episode of Bleav in Rams presented by Fanduel, Erin Coscarelli and Rams Super Bowl Champion Rob Havenstein have an insightful and impactful discussion with LA Rams Senior Vice President of Sports Medicine and Performance, Reggie Scott, on the ever-evolving world of NFL performance, recovery, and player development. What is the ONE trait that ultimately determines which players succeed in the NFL? What do the Rams do with rookies when they FIRST enter the building? Which stretch of the Rams' calendar is most physically demanding? Why is trust so important when it comes to the foundation of modern sports science...? Plus an interesting perspective on how veteran offensive lineman Rob Havenstein changed the way the organization evaluates talent... This conversation goes far beyond football. An INSIDE lens how the Rams use data, recovery, and individualized performance to gain an edge. The future of elite sports and why the Rams continue to lead the way... Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
In this episode of Bleav in Rams presented by Fanduel, Erin Coscarelli and Rams Super Bowl Champion Rob Havenstein have an insightful and impactful discussion with LA Rams Senior Vice President of Sports Medicine and Performance, Reggie Scott, on the ever-evolving world of NFL performance, recovery, and player development. What is the ONE trait that ultimately determines which players succeed in the NFL? What do the Rams do with rookies when they FIRST enter the building? Which stretch of the Rams' calendar is most physically demanding? Why is trust so important when it comes to the foundation of modern sports science...? Plus an interesting perspective on how veteran offensive lineman Rob Havenstein changed the way the organization evaluates talent... This conversation goes far beyond football. An INSIDE lens how the Rams use data, recovery, and individualized performance to gain an edge. The future of elite sports and why the Rams continue to lead the way... Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
Dr. Deb Muth 00:04What if the future of healing isn’t about replacing cells, but about teaching your body how to heal itself again? We keep hearing the words stem cells and exoomes thrown around like they’re interchangeable, but they’re not. One is regulated, controversial, and often misunderstood. The other is rapidly emerging as one of the most exciting communication systems in human biology. Dr. Deb Muth 00:33And here’s the real question no one’s asking. Are we actually regenerating tissue or are we just stimulating the body to remember how it used to heal? Tired of being told your labs are normal, but you still feel terrible? At Serenity Healthcare Center, we don’t chase symptoms. We find the root cause. hormones, gut health, autoimmune conditions, chronic fatigue, brain fog. Dr. Deb Muth 01:02We use cuttingedge functional and regenerative medicine to get you real answers and a real path forward. This isn’t your average doctor’s office. This is medicine the way it was meant to be practiced. You deserve to feel like yourself again. Visit serenityhealthcarecenter.com to book your appointment today. Let us help you heal from the inside out. Dr. Deb Muth 01:28Welcome back to Let’s Talk Wellness Now. I’m Dr. Deb, your host. And if you’ve been following regenerative medicine, you’ve probably noticed the confusion. Patients are asking me every week, are exoomes stem cells? Are stem cells legal in the United States? I heard the FDA is shutting down all these clinics. Can I even get this therapy? Do I have to leave the country for treatment? Today, we’re cutting through the noise. This episode is not hype. Dr. Deb Muth 01:54It’s not sales. It’s education so you can understand the science, the regulatory reality, and the clinical difference between stem cell therapy and exoome therapy. And here’s what I want you to know right up front. Yes, these therapies are being used in the United States every single day. Yes, they’re being offered by highly trained physicians in integrative and regenerative medicine clinics across the country. Dr. Deb Muth 02:22Some are being used in FDA registered clinical trials. Some are being used in observational studies and some are being used in clinical practice under physician discretion. The landscape is nuanced and you deserve to understand it. So, grab your cup of coffee or tea and settle in for a deep dive into the most understood therapies in regenerative medicine. Dr. Deb Muth 02:43what they actually are, how they work, the regulatory landscape, and how they might support your body’s natural healing capacity. Let’s talk wellness now. So, let me start by asking you something. When you hear the word stem cell, what do you picture? Most people imagine damaged tissues magically regenerating or a torn meniscus growing back, cartilage reforming it into an arthritic joint or damaged brain tissue being replaced with healthy new beautiful cells. It’s a beautiful vision. Dr. Deb Muth 03:15And while it’s not quite that simple, the reality is actually more sophisticated and honestly more beautiful. Stem cells are powerful and they absolutely work, but the way they work and the mechanism by which they support healing is far more elegant and more so than most people really understand. And if you’re going to invest in regenerative therapy, you deserve to understand what you’re actually receiving. Dr. Deb Muth 03:44So, let’s start at the beginning. What are stem cells? At their core, stem cells are undifferentiated cells. That means they haven’t yet decided what they want to be when they grow up. Unlike a heart cell or a skin cell or a bone cell which have already committed to a specific function, stem cells exist in this beautiful state of potential. Dr. Deb Muth 04:05They have two remarkable abilities. First, they can self-renew. They can make copies of themselves, maintaining a reserve of these powerful cells throughout your lifetime. Second, they can differentiate under the right conditions. They can transform into specialized cell types. Bone cells, cartilage cells, nerve cells, muscle cells, even blood cells. Dr. Deb Muth 04:27This is why they’ve captured the imagination of the medical world. The potential is extraordinary. Now, there are several types of stem cells and understanding the differences matters tremendously for both understanding how they work and understanding how they’re regulated. Adult mezzenymal stem cells. We call these MSC’s are the most commonly used regenerative medicine. Dr. Deb Muth 04:54These come from bone marrow, atapost tissue, that’s fat, and other adult sources. They’re what we can call multi-potent, meaning they can become several types of cells, but not every type. A bone marrow stem cell isn’t going to become a brain cell, for instance. It has potential but it’s directed potential. Dr. Deb Muth 05:19Then we have perinatal stem cells. These come from umbilical cord blood cord tissue or something called Wharton’s jelly which is the gelatinous substance inside the umbilical cord. These cells are younger, more potent, and research by Weiss and colleagues published in stem cells back in 2006 showed that Wharton’s jelly derived MSC’s have superior proliferation and differentiation potential compared to bone marrow derived cells. Dr. Deb Muth 05:48They’re like comparing a 20-year-old athlete to a 50-year-old athlete. Both can perform, but one has more reserve capacity, more vigor, and more regenerative potential. And this isn’t this is very important because the perinatal sources umbilical cord tissue Wharton’s jelly amniotic tissue these are what many regenerative medicine clinics in the United States are using today and they’re using them because these tissues are incredibly rich in not just stem cells but growth factors cytoines and exoomes. Dr. Deb Muth 06:21Then there are embryionic stem cells. These are pur potent and they become any cell type in the body, but they’re highly regulated, ethically controversial, and honestly, they’re not being used in clinical practice in the United States outside of the very specific FDA approved research trials. Dr. Deb Muth 06:41So, when clinics talk about stem cell therapy, they’re almost never talking about embryionic stem cells. Now, here’s where it gets interesting and this is the part that changes everything about how we understand regenerative medicine. When you receive stem cell therapy, let’s say someone injects umbilical cord derived messenymal stem cells into your arthritic knee, those cells do not typically engraft or become new tissue in any permanent way. Dr. Deb Muth 07:12They don’t set up shop in your joint and start cracking out new cartilage cells for the rest of your life. So what are they actually doing then? Well, in 2011, researchers Arnold Arnold Kaplan and Dennis Korea published a landmark paper in stem cells translational medicine that fundamentally changed how we understand MSC therapy. Dr. Deb Muth 07:35They proposed that we should stop calling memal stem cells and start calling them medicinal signaling cells. Why? Well, because their primary therapeutic benefit doesn’t come from what they become. It comes from what they secrete. Think of stem cells as incredibly sophisticated biological pharmacies. When you inject them into damaged tissue, that arthritic knee, that inflamed autoimmune condition, that injured brain, that don’t just sit there passively, they sense the environment. Dr. Deb Muth 08:07They detect inflammation. They recognize the tissue damage and they understand that the immune dysregulation is present and they see that and respond. They start pumping out hundreds of bioactive molecules, growth factors that tell your cells to repair and rebuild, cytoines that modulate inflammation, chemocines that recruit your body’s own healing cells to the area. Dr. Deb Muth 08:32And these tiny membranes bound packages called extracellular vesicles, including exosomes, which we’re going to talk about extensively today as well. These secreted factors are giving instructions to your native cells. They’re saying, “Let’s reduce inflammation. Let’s modulate your immune response. Let’s promote angioenesis. Dr. Deb Muth 08:53” That’s the formation of new blood vessels, bringing nutrients and oxygen. Let’s stimulate your own resident stem cells to wake up and get to work. Reduce cell death in damaged tissue and restore normal cellular function. This is called paracrine signaling. It’s the cellto cell communication. And this is where the real therapeutic power lives. Dr. Deb Muth 09:14The stem cells themselves, many of them die within days to weeks, but the cascade of healing they trigger, the signals they send, the programs they activate in your own cells, those effects can last for months or even years. Now, this understanding is crucial because it explains why both stem cell therapy and exoo therapy can be effective. Dr. Deb Muth 09:38The stem cells are powerful not because they become new tissue but because of the signals they send and exoomes are those signals isolated and concentrated. The biggest misconception in regenerative medicine is that stem cells replace tissue and in reality they coach healing more than they become healing. They’re biological educators teaching your body to remember how it used to heal before chronic inflammation, toxicity, and disease turned off all those programs. Dr. Deb Muth 10:12So if stem cells don’t exactly end graft and become the new tissue, if their power is in their signaling and then next logical question is why do we need the cells at all? Well, if we could isolate the messengers themselves, what if we could deliver just the communication systems without any of the complexity of the living cells? Well, that’s exactly what exosomes are. Dr. Deb Muth 10:38And they represent the cutting edge of regenerative medicine. So, let me paint you a picture of how cells actually communicate. Because for most medical history, we had it wrong. For decades, textbooks taught us that cells talk to each other in two basic ways. through direct contact like shaking hands or releasing signaling molecules that floated through the extracellular space like messages in bottles, simple chemical messages. Dr. Deb Muth 11:09But in the 1980s and 90s, researchers started discovering something far more sophisticated. cells were releasing these tiny membrane bound packages like a biological FedEx envelope kind of you know it was filled with complex specific cargo and these packages could travel through the blood cross the barriers that normally keep things out like bloodb brain barrier and deliver their contents to distant cells with remarkable precision. Dr. Deb Muth 11:38These are called extracellular vesicles. And exoomes are one of the most therapeutic important types. So what exactly are exosomes? Well, they’re nanosized vesicles, typically 30 to 150 nanome in diameter. To put that into perspective, a human hair is about 100,000 nanometers wide. These are incredible and most impossibly tiny. Dr. Deb Muth 12:09They’re released by virtually all cells in the body, but the most therapeutically interesting exoomes come from mezenymal stem cells. And those medicinal signaling cells we just discussed. And according to a landmark review of Raposo and Stervogal, they published in the journal of cell biology in 2013, exoomes are not cellular debris. They’re not waste products. Dr. Deb Muth 12:35They are precisely engineered communication vesicles or vehicles. Think of them as sophisticated delivery systems carefully packed, carefully labeled, and sent to specific destinations. very specific instructions. Inside each of these exoomes, you’ll find an incredibly sophisticated payload. They are microRNAs. These are small RNA molecules that can literally turn genes off or on in the recipient cells. Dr. Deb Muth 13:06They can tell a cell to start making more collagen, to reduce inflammatory proteins, to activate repair programs that have been shut down by chronic disease for a very long time. There are messenger RNAs, actual templates for protein production. And exoome can deliver these instructions for making healing proteins. There are proteins themselves, growth factors, cytoines, enzymes, all the molecular tools a cell needs to heal. Dr. Deb Muth 13:34And there are lipids, specialized fats that help the exoome membrane fuse with targeted cells, delivering the cargo inside. When an exoome reaches its target cell, it can either fuse the cell membrane and deliver its contents directly inside like a Trojan horse, or it can bind to surface receptors and trigger signaling cascades, setting off a chain reaction of healing responses. Dr. Deb Muth 14:01Either way, it’s delivering very specific targeted instruction. And here’s what makes this so powerful. Those instructions are tailored to what this recipient cell actually needs. So, let me give you some concrete examples of what the research actually shows because this is where it really gets exciting. When researchers inject MSC derived exoomes into hearts that had experienced eskeeia, reprofusion, injury, that’s damaged blood flow being cut off and then being restored. Dr. Deb Muth 14:36Kind of like what happens during a heart attack. Something remarkable happened. A study by Lei and colleagues published in stem cell research in 2010 showed that exoomes significantly reduced the size of the damaged area, reduced inflammatory cytoines that drive tissue destruction and promoted tissue repair signaling. The exoomes were telling the heart cells stop the inflammatory cascade, activate your survival programs and repair the damage. Dr. Deb Muth 15:06In cartilage research, tow and colleagues published work in biioaterials in 2017 showing that exosomes derived from MSC’s could promote cartilage regeneration in osteoarthritis models. And the exoomes carried specific microRNAs that told condondroytes cartilage cells to proliferate and make more extracellular matrix, the structural framework of healthy cartilage. Dr. Deb Muth 15:30for autoimmune conditions. Research by Blazic and colleagues in Frontiers in Immunology in 2014 demonstrated that MSC derived exoomes could shift immune cell behavior from pro pro-inflammatory to regulatory. They could take an overactive self-attacking immune system and restore balance and promote tolerance. And perhaps most exciting brain research, a study by Zinn and colleagues published in the journal of extracellular vesicles in 2013 showed that MSC derived exoomes could cross the bloodb brain barrier. Dr. Deb Muth 16:07That protective shield around your brain that normally keep things out and promote neurological recovery in stroke models. They reduced brain inflammation, promoted neuroplasticity, supported the formation of neural connections, and for mitochondrial dysfunction, which underlies so many chronic conditions, Morrison and colleagues published research and scientific reports in 2017 showing that MSC derived exoomes can actually deliver functional mitochondria or mitochondrial components to damaged cells. They’re not Dr. Deb Muth 16:40just sending instructions, they’re sending spare parts. They’re restoring the cellular powerhouses to produce energy. So why are exoomes fundamentally different from stem cells? Well, exoomes contain no living cells. They can’t replicate. They can’t end graph. And they have virtually no risk of immune rejection or tumor formation. Dr. Deb Muth 17:03Concerns that exist elevate rarely with cellular therapies. They’re essentially biological software updates for your cells. As Fineian Pitiger wrote in their seinal review in stem cells in 2017, MSC derived exoomes represent the active ingredient of stem cell therapy delivered in a cellfree format. That’s the key insight in the in the therapeutic benefit of stem cells and it comes from what they excrete. Dr. Deb Muth 17:33Then exoomes are the secretion isolated, concentrated, and standardized. From a practical clinical standpoint, exoomes offer several compelling advantages. First, consistency. Because exoomes can be isolated, characterized, and standardized, each dose can be remarkably consistent. With living stem cells, there’s variability based on donor age, health status, processing methods, and one batch may be robust, but another might be weaker. Dr. Deb Muth 18:05With exoomes, you can measure the content, measure the potency, and ensure the quality control. Second is storage. Exoomes can be liophalized. They can be freeze-dried and stored at room temperature or refrigerated for extended periods. Stem cells require cryopreserv preservation, careful freezing, careful thawing. They’re fragile. Dr. Deb Muth 18:31Exoomes are remarkably stable. And third, their safety profile. Without living cells, the risk of adverse imunological reactions is dramatically lower. You’re not introducing foreign cells that your immune system might recognize and attack. You’re introducing molecular messages. Fourth is scalability. You can harvest millions, even billions of exoomes from stem cell cultures without ever injecting the cells themselves. Dr. Deb Muth 19:01And you can produce large quantities, standardize them, and make them available to patients. Now, there is a caution here in doing this. The scalability can produce rogue cells, and we want to be cautious of that. So, here’s what I need you to understand. Exoomes don’t force healing. They remind the body how healing works. Dr. Deb Muth 19:24They’re not replacing damaged cells. They’re re-educating the cells you already have. They’re turning back time on the biological programs that got turned off by inflammation, toxicity, trauma, time, and chronic disease. Your body knows how to heal. It’s done its entire life. Every cut that closed, every bone that mended, every infection you fought off, your body orchestrated that healing. Dr. Deb Muth 19:51The problem is that chronic disease, chronic inflammation, toxic exposures, poor nutrition, stress, all of these things disrupt the communication networks that coordinate healing. And exoomes restore that communication. They’re like rebooting a computer that’s frozen. They reset the system and remind it how it’s supposed to function. All right. Dr. Deb Muth 20:14So, this would not be complete if we didn’t talk about regulation because this is where a lot of confusion exists. And I want you to be given a real picture. Not fear-mongering, not pretending. There aren’t regulatory considerations, but the actual practical reality of how regenerative medicine is practiced in the United States today. Dr. Deb Muth 20:38Here’s what you need to understand. The FDA regulates these therapies and they have specific frameworks, but there’s important nuances between regulatory text enforcement priorities and actual clinical practice. And there are also state level regulations that provide additional pathways. The FDA regulates human cells, tissues, and cellular and tissue based products. Dr. Deb Muth 21:05We call them HCT/PPS under two main pathways. Section 361 products are those that meet specific criteria. They’re minimally manipulated, intended for homologous use, meaning these tissues perform the same basic function in the recipient as it did in the donor. They’re not combined with non-tissue components and they’re either autotogus, meaning they come from your own tissue, or they have had minimal systemic effect. Dr. Deb Muth 21:38An example of a clear 361 procedure, your doctor harvests your own bone marrow, we call this PRP, performs minimally processing to or uh perform Yeah. performs minimal processing to concentrate the stem cells through a centriuge and injects it into your arthritic knee the same day. That’s autogus same day but minimally manipulated. Dr. Deb Muth 22:04This is unquestionably legal and is being done in regenerative medicine clinics across the country every single day. So there’s section 351 where products are those that don’t meet all the section 361 criteria. They’re classified as drugs or biologic products and they require FDA approval through clinical trials. Dr. Deb Muth 22:27Now here’s where this gets more nuanced. There are regenerative medicine clinics across the United States using stem cell and exoome therapies in different contexts. First FDA registered clinical trials. These are formal research studies with investigational new drug applications. Patients enroll in trials. They sign informed consents. Dr. Deb Muth 22:48They receive therapies as part of their structured research protocols. And this is completely legal and represents the gold standard for gathering evidence. Second is observational studies and registry programs. Many clinics are collecting systemic data on patient outcomes using these therapies even outside the FDA trials. Dr. Deb Muth 23:12They’re documenting results, tracking safety, and contributing to the growing body of clinical evidence. Third, there’s clinical practice under physician discretion. There are physicians using these therapies based on their own clinical judgment informed consent from patients and their interpretation of the regulatory framework particularly around minimal manipulation and homologous use. Dr. Deb Muth 23:34Now there are also state regulations that provide additional legal frameworks. So, for example, Florida has enacted the Right to Try Act and specific regenerative medicine legislation that allows physicians to offer certain stem cell therapies under the state oversight. Utah has passed similar legislation creating pathways for regenerative medicine products. Dr. Deb Muth 23:57And these state laws recognize that patients should have access to potentially beneficial therapies, particularly when used by trained physicians with appropriate informed consent. The regulatory question often centers around are these products minimally manipulated. Some products clearly are not. They’ve been cultured. Dr. Deb Muth 24:20They’ve been expanded in laboratories and those require FDA approval that they don’t have. The FDA has appropriately shut down clinics using those products. But there are other products that undergo processing that many physicians and manufacturers argue constitutes minimal manipulation. And these tissues are cleared, potentially fragmented or particulated to make them more suitable for injection, preserved using methods like cryopreservation or liophalization and packaged. Dr. Deb Muth 24:54But the cells are not cultured or expanded in the laboratory. The FDA has issued guidance suggesting that many of these processing steps constitute more than manipul minimal manipulation. But many physicians, particularly those who specialized in regenerative medicine for years, disagree with that interpretation and they believe that the processing qualifies as minimal manipulation and that the product should fall under section 361 when used for homologous purposes. Dr. Deb Muth 25:24Is there regulatory debate? Absolutely. The FDA and some clinicians have different interpretations of what constitutes minimal manipulation. But here’s the practical reality. There are hundreds of well-trained, bore certified physicians across the United States offering these therapies every single day. Dr. Deb Muth 25:42They’re doing so based on their understanding of the regulations, their clinical experience, their commitment to patient safety, and their belief that these therapies can help people who have exhausted conventional options. The FDA’s enforcement priorities have focused primarily on the most problematic cases. Clin clinics making blatant disease cure claims, products with documented safety issues, clear cases of cellular expansion and culture, or clinics operating with no medical oversight. Dr. Deb Muth 26:15Reputable regenerative medicine physicians are using products from companies that provide comprehensive documentation of their processing methods. third-party sterility testing, certificates of analysis showing bioactive content, and quality control measures that meet or exceed industry standards. Now, let me be very clear about something. Dr. Deb Muth 26:36Quality matters enormously. Not all stem cells and exoome products are created equal. Research by Burger and colleagues published in the Orthopedic Journal of Sports Medicine in 2021 analyzed 12 commercially available stem cell products and found that many contained zero viable cells, high levels of bacteria, endotoxins and inconsistent growth factor concentrations. Dr. Deb Muth 27:01This is why the company providing these biologic matters tremendously. You want products from manufacturers who provide transport documentation in sourcing and processing. Conduct third-party testing and sterility and potency. Offer certificates of analysis for each batch. Use standardized validated processing protocols. Dr. Deb Muth 27:24Have quality control measures that ensure consistency and don’t make outrageous cure claims or promise. The best regenerative medicine physician carefully vet their suppliers. They don’t use products from companies making unrealistic promises. They use products from manufacturers who are transparent, scientifically rigorous, and committed to quality. Dr. Deb Muth 27:46Now, you specifically ask about homologous use and collagen defects. So, let me address this directly for you. Under the FDA guidance, homologous use means the tissue performs the same basic function in the recipient as in the donor. So for connective tissue, tendons, ligaments, cartilage, fascia, all of that which are collagenrich structures using MSC’s or their derivatives could be considered homologous use. Dr. Deb Muth 28:17MSC’s in their native environment provide structural support to produce extracellular matrix including collagen. Using them to support healing in damaged collagen rich tissues like arthritic joints, torn tendons or degenerative ligaments is arguably the same basic function. So using exoomes derived from MSC’s to support collagen synthesis reduce inflammation and promote tissue healing in the same structures. Dr. Deb Muth 28:46Many practitioners argue this also qualifies as homologous use because you’re supporting the structure and function that MSC’s would naturally support. So here’s the bottom line on the regulatory reality. Regenerative medicine is available in the United States. It’s being offered by highly trained physicians in integrative and regenerative medicine clinics across the country. Dr. Deb Muth 29:11Some therapies are offered in FDA registered clinics and some are offered in observational studies. Some are offered in clinical practice under physician discretion, informed consent, and careful attention to safety. The regulatory landscape is evolving. There are ongoing discussions both federally and state levels about creating clearer pathways for these therapies. Dr. Deb Muth 29:32So, if you choose to go down this road, you want to work with physicians who understand the regulations, who use quality products from reputable manufacturers with rigorous testing and documentation, who are transparent about what they’re using and why, who discuss the current regulatory landscape honestly with you, and who prioritize your safety and truly informed consent above all else. Dr. Deb Muth 29:55This is not a lawless wild wild west. But it is also not as simple as everything is legal and unavailable. It’s a nuanced landscape that requires ethical knowledge. And these practitioners that have this knowledge have got to provide informed patients who understand both the potential benefits and the current regulatory context. Dr. Deb Muth 30:17So let’s have some fun here. Let’s talk about what really matters to you that are listening and that’s what conditions are being supported with these therapies. What does the research show and what are clinicians seeing in actual practice with patients? Because here’s what’s really important. We have both published research evidence and extensive clinical experience. Dr. Deb Muth 30:38And when the two align, that’s when we can feel confident and comfortable about using these approaches. So, let’s start where we have the most substantial evidence. joint health and muscularkeeletal conditions. For arthritis, we have good data. A systemic review by Tan and colleagues published in arthritis research and therapy in 2021 analyzed 20 randomized controlled trials in MSC therapy for knee osteoarthritis. Dr. Deb Muth 31:05They found significant improvements in pain and function particularly in mild to moderate disease. What’s really interesting is when researchers start analyzing whether it was the cells themselves or their secreted factors doing the work. They found that exoomeenriched preparations showed similar benefits to whole cell therapy. Dr. Deb Muth 31:26Now towen colleagues in the biioaterials paper from 2017 demonstrated that MSC derived exoomes could promote cartilage matrix synthesize and reduce inflammation markers. The exoomes carried microarnas that told cartilage cells to make more collagen and proteoglycans, the building blocks of healthy cartilage. Dr. Deb Muth 31:49In clinical practice, physicians are seeing patients with knee, hip, shoulder, and spinal arthritis, experiencing reduced pain, improved function, better motility, and in some cases, measurable improvements in their tissue. I want to share a story here with you because back in 2006, my husband was injured at work. Some of you might have heard me tell this story before. Dr. Deb Muth 32:11Um, he broke two discs in his back and underwent surgery very early on when we started using stem cells. They had put cages and plates in and they used MSC’s to put inside the cage to create a hardened bone so that he could have a fusion and hopefully not have any pain. At the time, what the physician didn’t realize or mistakenly did was he did not put any human bone mixed with these dead cadaavver bone MSC’s. Dr. Deb Muth 32:42And so the MSC’s never grew. They didn’t have anything to grow by. So the plates and the screws just kind of went back and forth for six months before he could see another physician that would look at him differently and understand what actually happened. That was very early on. Today we know so much more than we did before. Dr. Deb Muth 33:01Fast forward to 2014 when my husband was having problems and he couldn’t feel his legs, he couldn’t feel his feet. We decided to undergo uh exoo and stem cell therapy again and we saw a physician in Florida who harvested cells from his bone marrow and his blood and his fat and mixed that all together and then put that back into the back. Dr. Deb Muth 33:27and he had tremendous benefit from it. So, I tell this story because I want you to see the trajectory of how long this has been going on that we’ve been using this and we’re learning as we’re going and things are changing rapidly in this in this world. And so, what we know today and what I’m teaching you today may very well change in a month or six months or a year from now, but we have the foundation at least to understand what is helpful, what is not right now. Dr. Deb Muth 33:54But just be aware that if you’re embarking on exoome or stem cell therapy or MSC’s that you understand that this terrain is going to change. So back to my conversation about what other things can we treat? Well, we can treat tendon and ligament injuries, chronic tennis elbow, Achilles tendonopathy, rotator cuff tears, chronic planter fasciitis. Dr. Deb Muth 34:17These were researched by PA and colleagues in the American Journal of Sports Medicine in 2017 and it showed that bone marrow concentrate injections resulted in improved pain and function compared to steroid injections. Now this mechanism appears to be enhanced collagen remodeling and reduced chronic inflammation. Dr. Deb Muth 34:39These are structural collagenrich tissues using MSC’s or their derivatives for structural support which makes biological sense. It’s homologous use. It’s similar. So clinically we’re seeing athletes, active adults and people with chronic pain who failed physically um failed physical therapy, failed conservative treatments finding relief in this functional uh improvement in this functional world that we live in today. Dr. Deb Muth 35:07So, I want to be clear about what we’re doing here for joint and muscularkeeletal issues. We’re not growing completely new cartilage from scratch or severely destroyed joints. We’re not magically regenerating tissues that’s been gone for decades. That’s not possible here. What you’re doing when you’re using MSSE’s and exoomes is supporting the body’s natural ability to repair, reducing inflam inflammation and damage, and we’re driving progressive degeneration uh or we’re stopping the progressive degeneration. By reducing the Dr. Deb Muth 35:41inflammatory damage, we’re stimulating resonant stem cells that have been dormant. We’re improving blood flow and uh uh oxygen to the tissues like cartilage and tendons. and we’re organizing the body to start creating its own quality collagen as it heals. So, it’s a regenerative support, not a tissue replacement. Dr. Deb Muth 36:07But for many people, this support is lifechanging. So, let’s talk about autoimmune disorders now because this is one of the most exciting and unrecognized applications. autoimmune conditions like rheumatoid arthritis, lupus, MS, Crohn’s disease, ulcerative colitis, Hashimoto’s, they all involve the immune system and the immune system is deregulated. Dr. Deb Muth 36:30And so basically your immune system is seeing this tissue as foreign and it’s attacking it. These MSC’s and their exoomes have profound immune modulatory properties. They don’t suppress the immune system like steroids or imunosuppressive drugs. They modulate it helping to restore balance. So for rheumatoid arthritis, research by Weang and colleagues in stem cells translational medicine in 2016 showed that MSC derived exoomes could shift the balance of immune cells, reducing pro-inflammatory TH7 cells that drive joint disruption uh and increase Dr. Deb Muth 37:08regulatory TE-C cells that maintain immune tolerance. So for MS, a clinical trial by Kasus and colleagues published in archives of neurology back in 2010 evaluated autotogus MSC therapy and MS patients and they found evidence of reduced disease activity, improved neurological function and decreased inflammatory uh lesions on MRI scans. Dr. Deb Muth 37:34The proposed mechanism is MSC’s and their exoomes reduce inflammatory cytoine production promote regulatory imu immune populations support remination of damaged nerves that is rebuilding the protective coating around the nerve fibers and it reduces bloodb brain barrier permeability which prevents immune cells from attacking their brain and spinal cord. Dr. Deb Muth 38:02And so for inflammatory bowel disease, the research by Barnholm uh sorry Barnhorn and colleagues in gut in 2020 showed that MS cell MSC derived extracellular vesicles could support mucosal healing and reduce inflammation in the gut lining. They appeared to restore intestinal barrier function, healing that leaky gut and modulating local immune responses. Dr. Deb Muth 38:30So in clinical practice, physicians are seeing patients with autoimmune conditions, experiencing reduced disease flares, decreasing the need for imunosuppressive medications, improving energy and quality of life, and in some cases extending periods of remission. But here’s what I want you to understand. Dr. Deb Muth 38:52When you see these therapies for autoimmune conditions, we are supporting immune regulation and reducing inflammatory damage. We are not treating or curing the disease in a conventional sense. These therapies work best as part of a comprehensive functional medicine approach that also addresses gut health because 70% of your immune system lives in your gut and environmental triggers like mold, heavy metals, chemical toxins that can drive autoimmune responses, chronic infections that can trigger immune disregulation, stress and nervous system imbalance. And Dr. Deb Muth 39:29these nutritional deficiencies are necessary to help improve the immune function. So regenerative therapy without addressing root causes is like bailing water out of your boat without plugging the hole. You might get temporary relief, but the underlying problem still remains. So let’s talk about neurological conditions. Dr. Deb Muth 39:52And this is where the science gets truly fascinating. for traumatic brain injury and concussion. Research by Zang and colleagues in the Journal of Neurot Trauma in 2015 showed that MSC derived exoomes could reduce brain inflammation, promote neuroplasticity, that’s the brain’s ability to rewire itself and improve cognitive outcomes in animal models. Dr. Deb Muth 40:17The exoomes crossed the bloodb brain barrier, delivered neuroprotective proteins and microRNAs. They reduced inflammation, supported mitochondrial function in injured neurons and promoted both new blood vessels from new blood formation and neurogenesis and the birth of new neurons occurred. Neurological recovery requires a multi-systematic approach. Dr. Deb Muth 40:42Exoomes may support neural repair, but they work best combined with hormone optimization, growth hormone, testosterone, thyroid, pregnnolone, mitochondrial support compounds like NAD, CoQ10, PQQ, carnitine, all of those things that we use traditionally in functional medicine. Now for stroke recovery, there was research by Zinn and colleagues in the journal of extracellular vesicles that showed MSC derived exoomes reduced the size of brain damage and improved neurological recovery in animal models. There was a Dr. Deb Muth 41:19Parkinson’s disease study done by Kimoji and colleagues in the movement disorders in 2018 that suggested that MSSE derived exoomes could support dopamineergic neuron survival and those are the cells that die in Parkinson’s and it can help to reduce neuroinflammation. Clinically, physicians are seeing improvements in patients with postconussion syndrome, chronic traumatic brain injury, early stage cognitive decline, and other neurodeenerative conditions. Dr. Deb Muth 41:52These are not cures, but meaningful improvements in cognitive function, mood, energy, and quality of life. Now, let’s talk about autism spectrum disorder very carefully here because this is a very sensitive but very important topic for families. There have been several clinical trials that have explored MSC therapy for autism. Dr. Deb Muth 42:16Liv and colleagues published research in stem cell translational medicine in 2013 showing improvements in social interaction, communication, and behavioral symptoms in children with ASD who received cord blood MSC’s. Dawson and colleagues in 2017 conducted randomized trial autotogus cord blood infusion and found modest improvements in social communication particularly in children with higher baseline immune dysregulation. Dr. Deb Muth 42:47The proposed mechanisms for modulation of neuroinflammation support the mitochondrial function because many children with autism show evidence of mitochondrial dysfunction, reduction of oxidative stress, improvement in gut brain access dysfunction and modulation of immune dysregulation. In clinical practice, some physicians are seeing improvements in some children, better eye contact, increased language development, reduced sensory sensitivities, improved social engagement, but responses vary significantly, and we cannot predict which children will benefit most. So for Dr. Deb Muth 43:26families considering regenerative approaches for autism, these therapies are supporting the body’s healing mechanisms, reducing neuroinflammation, supporting cellular energy production, modulating immune function. These should only be considered as part of a comprehensive biomedical approach that includes dietary interventions to address food sensitivities, support gut health, environmental toxin removal, particularly heavy metals and chemical exposures, gut healing protocols with targeted probiotics and nutrients, Dr. Deb Muth 44:00metabolic testing and targeted supplementation, and evidence-based on behavioral and developmental therapies. These therapies should only be pursued with practitioners who are honest about what we know and what we don’t know and who follow rigorous safety protocols who never promise cures and who view regenerative medicine as a tool in the comprehensive healing strategy, not a standalone miracle. Dr. Deb Muth 44:26Not only that, these therapies will most likely need to be given several times over the course of this person’s lifetime, possibly even on an annual basis. And this is really important because it is not a oneandone. It is not a one-sizefits-all, and it needs to be looked at as a long-term option for working with autism. So, since we’re looking at stem cells versus exoomes, living cells, with stem cell therapy, you’re receiving living cells that can survive in your body for days to weeks. Dr. Deb Muth 45:02With exoome therapy, there are no living cells, just biological messages they would have sent. So, replication stem cells can potentially replicate. Although therapeutically this happens minimally, exoomes cannot replicate. They deliver the cargo and then they are cleared by your body. With stem cells, it’s primarily paracrine signaling. Dr. Deb Muth 45:28They’re coaching your cells to heal. With exoomes, it’s pure signaling, pure reprogramming your cells without any cellular component. Stem cells as we talked about can be autotogus from your own bone fat, blood or um bone marrow or allergenic from umbilical cord tissue or Wharton’s jelly. Dr. Deb Muth 45:50Exoomes are typically derived from cultured MSC’s often from umbilical cord or bone marrow sources and both can be given by local injection for targeted treatment of joints and tissues and exoomes can be given intravenously for whole body systemic support. both have um low immun immunogicity. I can’t say that word today. Dr. Deb Muth 46:17But exoomes have even lower risk since they contain no cellular material. Now, it’s absolutely critical for you to understand that there are massive quality differences. We’ve talked about this earlier. I want you to be very aware of this and have a conversation with any of the practitioners that you’re considering undergoing this treatment with. Dr. Deb Muth 46:37Here is where it matters more than anything when you’re considering regenerative medicine, the quality of the products and the expertise of the practitioner. Because the reality is not all regenerative medicine products are created equal. We all know that when we take different supplements and not all practitioners understand these therapies at the same depth. Dr. Deb Muth 46:58You want to look for practitioners that are board certified or have some kind of specialized regenerative medicine training. You want to know their clinical experience. How much have they done these procedures? How long have they done this? You want honest communication about the evidence and the limitations in this. Dr. Deb Muth 47:17You want a comprehensive functional medicine approach to go along with these therapies. And you want somebody that’s transparent about their informed consent and their regulatory status. If you have people that are uh claiming that they can cure disease or giving you guarantees, that is not that is not a good practitioner to work with. Dr. Deb Muth 47:37If you have high pressure sales tactics, you need to decide today limited supply for a week. These are marketing manipulations. It’s not medical care. You want to be cautious of extremely low prices because quality regenerative products are expensive to source, process, and test. and store. And if somebody’s offering stem cells or exoomes for a few hundred dollars, seriously, you need to question the quality, the safety, and where they got this from. Dr. Deb Muth 48:09So before undergoing any regenerative therapy, make sure you’re having a very, very lengthy conversation with the person and so you truly understand exactly what you’re getting, how it’s going to be delivered, and what they’re going to do. If there’s one thing I want you to take away from today is that your body has remarkable capacity to heal when given the right biological signals and the right environment. Dr. Deb Muth 48:35Stem cells and exoomes are powerful tools for providing biological signaling that can reduce inflammation, modulate immune function, support tissue repair, and restore cellular communication that’s been disrupted by chronic disease and inflammation. These therapies are available in the United States through trained physicians working in FDA registered trials, observational studies, and clinical practice, and using quality products from manufacturers with rigorous testing and quality control. Dr. Deb Muth 49:04So before you invest in regenerative medicine, do your homework. Ask detailed questions about product quality and source. Verify the products come from reputable manufacturers with certificates of analysis, third-party testing. Work with experienced practitioners. And remember, no injection, no infusion, no biologic can overcome ongoing toxic exposure, chronic stress, poor nutrition, gut dysfunction, and inadequate sleep. Dr. Deb Muth 49:34True healing requires your body and you to actively participate in this healing. If you are unwilling to address the root causes and change the lifestyle factors that disrupted your health in the first place, the biologics can amplify your healing signals, but you have to create the internal environment where healing can actually happen. Dr. Deb Muth 49:56So, I hope this episode has helped you understand regenerative medicine more clearly. Share it with somebody who’s looking for healing beyond the conventional approaches. And until next time, this has been Let’s Talk Wellness Now. Have a blessed day. >> Welcome to Let’s Talk Wellness Now, where we bring expert insights directly to you. Dr. Deb Muth 50:16Please note that the views and information shared by our guests are their own and do not necessarily reflect those of Let’s Talk Wellness Now, its management, or our partners. Each affiliate, sponsor, and partner is an independent entity with its own perspectives. Today’s content is provided forformational and educational purposes only and should not be considered specific advice, whether financial, medical, or legal. Dr. Deb Muth 50:41While we strive to present accurate and useful information, we cannot guarantee its completeness or relevance to your unique circumstances. We encourage you to consult with a qualified professional to address your individual needs. Your use of information from this broadcast is entirely at your own risk. Dr. Deb Muth 51:00By continuing to listen, you agree to indemnify and hold Let’s Talk Wellness Now and its associates harmless from any claims or damages arising from the use of this content. We may update this disclaimer at any time, and changes will take effect immediately upon posting or broadcast. Thank you for tuning in. We hope you find this episode both insightful and thought-provoking. Listener discretion is advised.The post Episode 265 – The Future of Healing: How Exosomes Re-Educate Your Body to Heal Itself first appeared on Let's Talk Wellness Now.
Doug talks shoulder pain, posture, rotator cuff tears, frozen shoulder, arthritis, treatment plans, and more on the WRAM Morning Show.
There are many outstanding leaders in the sports medicine and musculoskeletal rehabilitation world. How did they get there? What decisions did they make that have got them to where they are today? In today's episode, Dr Amber Donaldson shares what she is looking for in the next generation of sports medicine leaders, how she has approached developing her own career, and her advice for early-career clinicians looking to establish themselves in elite sports medicine. Dr Donaldson is the Vice President - Sports Medicine at the United States Olympic and Paralympic Committee.
Fitness mit M.A.R.K. — Dein Nackt Gut Aussehen Podcast übers Abnehmen, Muskelaufbau und Motivation
Bizeps-Curls schlagen Kurzhantel-Rudern beim Muskelwachstum – mit 11 Prozent gegen 5 Prozent. Eine Zahl aus dem Journal of Strength and Conditioning Research, die so ziemlich allem widerspricht, was Du in den vergangenen zehn Jahren über „echtes“ Krafttraining gehört hast.In dieser Folge räumt Mark mit einem der hartnäckigsten Dogmen der Fitness-Welt auf und zeigt Dir, warum reine Grundübungen Dich auf einem Plateau festkleben lassen können – und was Du stattdessen tun solltest. Du erfährst: Was die aktuelle Studienlage WIRKLICH zum Vergleich Grundübung vs. Isolation sagt – mit drei Ergebnissen, die selbst erfahrene Trainierende überraschen Wie die Wissenschaft zeigt, dass richtiges Krafttraining altersbedingte Muskelveränderungen nicht nur stoppt – sondern umkehrt Die Tischler-Formel: Wann Du den Hobel benötigst, wann Du zum Schleifpapier greifen solltest Die 80/20-Regel für effektives Krafttraining – und warum sie für die Ü40-Crew besonders wertvoll ist Drei Quick-Wins, die Du sofort umsetzen kannst Viel Spaß beim Reinhören!____________*WERBUNG: Infos zum Werbepartner dieser Folge und allen weiteren Werbepartnern findest Du hier.____________
Listen to our latest podcast as we break down our favorite orthopedic surgery and sports medicine movie movements from films such as Trainwreck, The Dark Knight Rises, Friday Night Lights, and Rookie of the Year (and more!)
LIVE from Ted's Shoe and Sport in Keene, New Hampshire. We welcome a PodFam favorite and running coach Karen Jordan (KJ) and Back in Action Chiropractor, Dr. Frank Abbate.In our conversation with KJ and Dr. Frank, we talk about injury prevention, KJ's recent hip replacements, and the importance of proactive health care for athletes. Discover insights on full-body assessments, recovery timelines, and how to invest in long-term wellness.Ted's Shoe and SportBack In Action Chiro WebsiteBack In Action InstagramKJ's InstagramKey TopicsFull-body assessment for injury preventionTiming and decision-making for hip replacementRehab strategies for athletes post-surgeryImportance of investing in long-term healthCollaborative approach between chiropractor and athleteChapters00:00 Introduction and Setting the Stage01:07 Meet Dr. Frank Abbate: A Journey into Chiropractic Care05:07 Understanding the Back to Action Plan09:19 KJ's Hip Journey: From Pain to Surgery19:01 The Surgery Experience and Recovery Insights22:19 Navigating Major Surgeries: Hysterectomy vs. Hip Replacement25:53 The Road to Recovery: Expectations and Realities27:38 Pre-Surgery Preparation: Strengthening for Recovery29:03 Aha Moments: Building Confidence in Recovery31:28 Investing in Health: The Importance of Self-Care34:41 Building Relationships: Coaching and Support Systems38:05 Looking Ahead: Future Goals and AspirationsMy Race Tatt's - Check out My Race Tatts and support the pod when you buy your next set by using our My Race Tatt's Link.Strava GroupLinktree - Find everything hereInstagram - Follow us on the gram YouTube - Subscribe to our channel Patreon - Support usThreadsEmail us at OnTheRunsPod@gmail.comDon't Fear The Code Brown and Don't Forget To Stretch!
What is cultural distress? It is a negative response rooted in a cultural conflict where the patient lacks control over their situation. It results in more physiologic effects on the body resulting in allostatic overload. To prevent this, healthcare practitioners must use strategies such as cultural humility to help patients navigate healthcare. Come find the best ways to deliver culturally sensitive care in any setting.
In this episode, Eric welcomes Dr. Robby Sikka, who brings a wealth of sports medicine research experience across a variety of sports. Robby shares insights about the dramatic rise in injuries in professional tennis while also speaking to the broader landscape of sports medicine trends across high level sports.
The number of surgical procedures for musculoskeletal diseases such as osteoarthritis has increased exponentially over the past years, some of which are unnecessary and leave patients no better off than they were before. Knee replacement surgery can be a wonderful and cost-effective treatment for end-stage osteoarthritis but only when less invasive treatments have failed. There are many factors driving the alarming rates of increased surgery ranging from system-level factors such as inadequate reimbursement for physiotherapy treatment to personal-level factors such as individual beliefs and education of patients and their health care providers. Frequently referrals are made to surgeons as primary care doctors feel there is nothing more they can do. If you are referred it is important to be prepared for what that consultation will involve and to consider whether you truly want/ need surgery.On this episode of Joint Action, we are joined by Dr Howard Luks to discuss this topic.Dr. Howard Luks is a Board-Certified Orthopaedic Surgeon and Sports Medicine specialist. Howard graduated from New York Medical College and completed his Orthopaedic Surgery residency in 1996 and a fellowship in Sports Medicine at the Hospital for Joint Diseases in NYC in 1997. His focus is on injuries that involve the shoulder, knee, and elbow. He is the Chief of Sports Medicine and Arthroscopy at New York Medical College and Advanced Physician Services.CONNECT WITH HOWARDWebsite: https://www.howardluksmd.com/Podcast: https://www.howardluksmd.com/podcast/the-paul-and-howard-show/CONNECT WITH USNaia Health: https://www.naiahealth.com.au/st-leonards-hubJoin one of our trials https://www.osteoarthritisresearch.com.au/current-trialsInstagram: @ProfDavidHunterEmail: hello@jointaction.infoWebsite: www.jointaction.info/podcastIf you enjoyed this episode, don't forget to subscribe to learn more about osteoarthritis from the world's leading experts! And please let us know what you thought by leaving us a review! Hosted on Acast. See acast.com/privacy for more information.
Durante años pensamos que bastaba con caminar para mantenerse bien. Pero las nuevas recomendaciones del American College of Sports Medicine dejan algo muy claro: el entrenamiento de fuerza ya no es solo para ganar músculo o verse mejor, sino una herramienta fundamental de salud y longevidad.En este episodio de Hablando en Plata, Adriana Valladares conversa con la entrenadora personal Noemí Pérez Núñez sobre por qué trabajar fuerza después de los 50 puede marcar una enorme diferencia en movilidad, equilibrio, prevención de caídas, autonomía y calidad de vida.Hablan también de algo muy importante: no se trata de vivir en el gimnasio ni de levantar enormes pesas. Lo que realmente importa es la constancia. Cómo empezar, cómo construir el hábito, qué ejercicios básicos funcionan y por qué nunca es tarde para comenzar.Además, Noemí comparte ejercicios sencillos para tren superior e inferior que pueden hacerse en casa.¡Cuéntanos qué te pareció este episodio y no olvides seguirnos en nuestras redes sociales!YouTube
On this week's edition of Inside Southern Miss Athletics, John Cox, The Voice of the Golden Eagles, visits with the Director of Athletics, Jeremy McClain, to talk about several topics regarding Golden Eagle Athletics. Cox also chats with Joe Bolden, the Defensive Coordinator and linebacker coach for Golden Eagle football, as well as Aaron Hill, the Assistant Athletic Director for Sports Medicine.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Urolithin A (MitoPure)--Mitophagy, Muscle Recovery, Immunity, and Skin Health: Dr. Brad Currier, clinical trial manager at Timeline, a Swiss biotech company, details urolithin A (MitoPure), a postbiotic derived from pomegranate precursors that most people cannot produce due to microbiome differences. Currier explains MitoPure's mechanism—stimulating mitophagy to recycle dysfunctional mitochondria—and reviews evidence from multiple clinical trials. He reveals a Sports Medicine study in elite male distance runners showing reduced creatine kinase and lower perceived exertion, suggesting improved recovery, plus trials in middle-aged and older adults showing improvements in strength, six-minute walk test, and VO2 max at 500 mg–1 g doses. They also cover a Nature Aging immune study reporting rejuvenation of stem-like CD8 T cells with improved mitochondrial fatty acid oxidation, ongoing research directions, supplement quality/testing for athletes, and topical urolithin A skincare trials and partnerships, including L'Oréal Lancôme.
Sports Medicine at the Highest Level with Dr. James Losito
Water: It's essential to life, but it can also cause devastation during severe weather. Brooke Gunderson, BSN, RN recounts the overwhelming flooding and infrastructure failure that she experienced as an emergency room nurse during Hurricane Helene in Boone, North Carolina. The extreme conditions, which included the loss of power and water, forced families and the health care providers to improvise just to meet basic needs. In the aftermath, the experience reshaped her perspective on preparedness, resilience, and the importance of community during disasters. Brooke Gunderson, BSN, RN is an emergency room nurse, mother of two daughters, and wife to a Sports Medicine physician. She now lives in Cookeville, Tennessee after recently relocating from Boone, North Carolina, where she witnessed the impact of Hurricane Helene as it moved through the Appalachian community. Related ResourcesHurricane Season is ComingHurricane season poses significant risks to children, families and healthcare systems. Explore curated resources to help clinicians, caregivers and communities prepare, respond and recover effectively. The Disaster Medicine Handbook: A Quick Reference This guide supports hurricane readiness by breaking down core disaster response concepts (preparedness, surge capacity, triage, crisis standards of care, reunification, and ICS) that hospitals and communities rely on before, during, and after major storms. Pediatrics & Obstetrics Module Collection - Weather Emergencies and DisastersEMS providers play a vital role in natural and manmade disaster response, from hurricanes and floods to nuclear incidents. North Carolina ranks among the most impacted states, with frequent severe weather and three active nuclear reactors posing additional risk. This course prepares EMS professionals to respond quickly, safely, and effectively during large-scale emergencies—enhancing readiness, coordination, and public safety. Strengthen your disaster response skills and be ready to serve your community when it matters most.
Dr. Courtney Conley holds a Doctorate in Chiropractic Medicine as well as two bachelor's degrees in Kinesiology and Human Biology. The founder and creator of Gait Happens, she has worked with professional athletic teams including the Phoenix Suns, New York Yankees, Cleveland Browns, New York Giants, San Francisco 49ers, and Minnesota Vikings. Dr. Conley is Head of Patient Care at Total Health Solutions and Total Health Performance, premier healthcare destinations renowned for their comprehensive and science-based approach to patient care. Dr. Milica McDowell holds two Bachelor of Science degrees (Exercise Physiology and Health Promotion, (Montana State University), a master's degree (Physical Therapy, University of Colorado Health Sciences Center), and a Doctorate degree (Physical Therapy, Idaho State University). She served as a university faculty member in Human Performance for nearly a decade, has developed numerous medical education curricula and has been an invited speaker on many national stages, including the American Physical Therapy Association and American College of Sports Medicine's conventions. Today on the show we discuss: why the 10,000 step rule is a myth rooted in marketing not science, how walking is a biological necessity that impacts your metabolism brain and mental health, why small “micro walks” can dramatically improve mood confidence and long-term consistency, the truth about fat loss and why walking works when you stack it with better sleep breathing and nutrition, how modern shoes are weakening your feet and what to do instead, and how to build a simple walking routine that actually improves longevity reduces depression and lowers your risk of disease and much more. Learn more about your ad choices. Visit megaphone.fm/adchoices
Listen to our latest podcast as orthopedic clinician scientists, Dr Brian Feeley and Dr Drew Lansdown, break down what you need to know about stem cells in 2026. What exactly are they? Are their applications in orthopedic surgery? Who is a candidate?
In Episode 4 of The Research Rundown, hosts Paul Buchheit (Head Athletic Trainer, Phillies) and Joe Rauch (Assistant Athletic Trainer, Phillies) are joined by Brad Pearson (VP of Sports Medicine, Red Sox) to break down the relationship between training load and injury risk. Using the paper “Training Load and Injury: Causal Pathways and Future Directions,” the group explores what the research actually says about causality, common misconceptions, and how athletic trainers can apply these insights in real-world settings.View the full paper here: https://pubmed.ncbi.nlm.nih.gov/33400216/For more information about PBATS and athletic training, visit pbats.com.
Episode Title: Act I: The Ache That Steals the Spotlight Low back pain can silence your artistry—but it doesn't have to steal your spotlight. In this episode of Performers Happiness in the Arts (PHARTS), Jenna Kantor, PT, DPT—dance medicine specialist, performer, and founder of Jenna Kantor Physical Therapy (JKPT)—dives into the world of low back pain for dancers, singers, and actors. You'll hear about: Why 67% of dancers, 54% of singers, and 52% of actors experience low back pain (Sweeney & McAuley, University of Hertfordshire, UK, 2016; Angadi et al., Ohio State University, 2019; Fryer, Australia, 2018) How technique habits, posture, and overuse lead to pain The role of performing arts physical therapy in recovery and prevention (Smith et al., Journal of Dance Medicine & Science, NYC, 2021) How guided movement can speed recovery by 30% (O'Sullivan et al., British Journal of Sports Medicine, 2020) Whether you're mastering Hamilton choreography, belting out Defying Gravity, or performing an intense monologue in Hadestown, this episode gives you the tools to stay strong, pain-free, and in the spotlight.
On this episode of the AMSSM Sports Medcast, host Dr. Jeremy Schroeder, DO, is joined by Dr. Amy West, MD, to discuss the hot topic of peptides in sports medicine. In their conversation, Dr. West and Dr. Schroeder discuss the following: Breaking down what peptides are, with a focus on compounds like BPC-157 and TB-500 that have gained traction among athletes Reviewing what the current – though limited – evidence actually shows, separating legitimate promise from overhyped claims Examining where patients are sourcing these compounds and the safety considerations clinicians need to be aware of How to provide a practical patient counseling framework: meet patients where they are, guide them toward safer sourcing and prioritize foundational health habits first Dr. West is a PM&R-trained sports medicine physician, an Assistant Professor at Northwest Health and a Team Physician at Hofstra University. Her clinical and research interests include the female athlete, adaptive sports, lifestyle medicine, transgender athletes and nutrition. She is active in the CrossFit community, serving on the CrossFit Games Medical Team and participating in various Crossfit functions and outreach events.
We've all seen it: the acute ACL patient who drags their leg into the clinic, unable to squeeze their quad to save their life. We call it Arthrogenic Muscle Inhibition (AMI), and for years, we've treated it as a stubborn, long-term enemy. But a fascinating new study from the American Journal of Sports Medicine suggests we might be overcomplicating it.Researchers analyzed 300 acute ACL patients and found that while AMI is incredibly common (affecting over half of patients), it's also surprisingly fragile. In fact, they found that nearly 80% of cases could be fully reversed in a single session with simple exercises. In this episode, we dive into the 'Red Flags' that predict quad shutdown—including one common sleeping habit you need to ban immediately—and how to flip the switch back on for your patients.To see full show notes and more, head to: https://mikereinold.com/risk-factors-of-arthrogenic-muscle-inhibition----------ACL Rehab MasterclassMy new course on the complete guide to criteria-based ACL rehab testing in return to sport is almost here. Sign up for the presale list for a huge VIP discount and to be notified first:https://mikereinold.com/acl Click Here to View My Online CoursesWant to learn more from me? I have a variety of online courses on my website!Disclaimer: This post contains affiliate links. If you make a purchase, I may receive a commission at no extra cost to you.Support the show_____Want to learn more? Check out my blog, podcasts, and online coursesFollow me: Instagram | Twitter | Facebook | Youtube
In this episode of Inside Athletic Training, we're joined by Dr. Cameron Roth and Andrew Rizza, co-hosts of the Behind the Sports Medicine Podcast, for a conversation on how they broke into podcasting, the standout guests and moments from their show, the evolution of athletic training, and where the sports medicine profession is headed next.Check out the Behind the Sports Medicine podcast hereMore about Dr. Roth: https://www.linkedin.com/in/cameron-roth-4160b91b0/More about Andrew Rizza: https://www.linkedin.com/in/andrew-rizza/ For more information about PBATS and athletic training, visit pbats.com.
Send us Fan MailIn episode #181 we unpack the latest research in cycling nutrition with Dr. Jamie Whitfield. Learn how these can impact athletic performance, recovery, and hydration strategies across various cycling disciplines.Key Topics Explored:The UCI Sports Nutrition Project and the evidence base for supplementsSodium citrate and bicarbonate, glycerol and ketonesStrategies for hyperhydrationJamie Whitfield earned his PhD in exercise physiology and muscle metabolism from the University of Guelph and is now a Senior Lecturer and researcher in the Centre for Human Metabolism & Performance at Australian Catholic University. His research utilizes a variety of research models to gain a better understanding of how nutrient availability alters skeletal muscle metabolism, and whether it can promote or inhibit training adaptation and, ultimately, human performance. He is currently an Associate Editor for the American College of Sports Medicine's flagship journal Medicine & Science in Sports & Exercise and is an Exercise and Sport Science Australia Accredited Sport Scientist.Please note that this podcast is created strictly for educational purposes and should never be used for medical diagnosis or treatment.RESOURCES:FREE RESOURCE: Supplements for Performance Free Guide DIVE DEEPER: Supplements that Improve Performance CourseFOLLOW JAMIE:X: @jwhitfieBluesky: jwhitfie.bsky.socialEuropean Sports Conference, July 2026MENTIONED:UCI Sports Nutrition Project: Considerations and Applications for the Use of Sports Food and Supplements to Improve Performance in CyclingEpisode 91 with Jamie Whitfield: Muscle Metabolism, High Carb vs High Fat, Supplements & Training AdaptationFullscript (for reputable supplements certified safe for sport)Supplements Mentioned:Sodium BicarbSodium CitrateGlycerolExogenous KetonesDietary Nitrates (Beetroot)MORE NRApply to work with Kyla → https://p.bttr.to/3ZrwzcFUse code NEWPOD10 for 10% off our meal plans → https://nutritional-revolution.com/products/CONNECT Instagram → www.instagram.com/nutritionalrevolutionSponsorship inquiries → kyla.c@nutritional-revolution.comInterested in having your biomarkers or nutrigenomics checked? Email us at nutritionalrev@gmail.com TRUSTED RESOURCES Supplements (save 20%) → https://us.fullscript.com/welcome/kchannellFeed Club ($20 off) → https://thefeed.com/teams/nutritional-revolutionKyla's top picks → https://shopmy.us/shop/nutrevFollow us @nutritionalrevolution
Welcome back to another episode of A Stride Above! In this episode, Dr. Colton Ramstrom sits down with extern Mia to discuss her path from Taiwan to hands-on clinical experience in Florida. Her journey reflects how passion for horses, combined with real-world exposure, shapes future leaders in equine veterinary care and equine sports medicine.In this episode, you'll learn:• How early experiences with horses can lead to a career in equine veterinary services.• Why hands-on work with hospital rounds, medications, and lameness exams builds strong clinical skills.• The impact of limited access to horse veterinarians and how it can inspire change in equine care.• How practical skills like horse handling and anatomy improve confidence in equine performance care.• Why curiosity and initiative are essential for growth in equine wellness and veterinary medicine.This episode highlights the value of experience, mentorship, and global perspective in horse care. Tune in now and share this episode with someone pursuing a future in equine veterinary medicine.Links For You:• Our Website • Facebook • Instagram • Youtube Dr. Alberto Rullan, VMD• Website• LinkedIn• Instagram
Talking about the summer programs at the University of Kansas Health System's Sports Medicine and Performance Center
Today, I'm excited to welcome Debra Atkinson back to the podcast for our third conversation. Debra holds both a BS and an MS in exercise science, with additional training in sports psychology, and served for many years as a senior lecturer in a university kinesiology program. She is a respected voice in the menopause space and an outstanding resource for personal training, coaching, and professional development for midlife women. In today's discussion, we explore key nuances and emerging trends in the fitness industry, including insights from recent surveys conducted by the American College of Sports Medicine. We unpack why many midlife women are drawn to the wrong types of workouts and the downstream consequences of those choices. We also examine what happens as estrogen levels decline, particularly its impact on muscle protein synthesis, and how this increases the risk of injury and tendon and ligament damage. We dive into strategies for avoiding frailty, the effects of chronic under-fueling, how nutritional choices- especially sugar, alcohol, and underlying food sensitivities can exacerbate hot flashes and other symptoms, and the importance of VO₂ max. To wrap up, Debra answers a series of rapid-fire questions, ranging from the one exercise every woman over 40 should master to conversations around zone two training, vibration plates, weighted vests, and more. This conversation with Debra Atkinson is truly invaluable, and I know you'll walk away with practical and empowering insights. IN THIS EPISODE, YOU WILL LEARN: Why social media exercise trends can often be misleading How habits, conditioning, and attachment to old exercise patterns impact women's exercise choices Why women's injury risk increases as estrogen levels decline How travel, jet lag, and holiday foods can amplify stress and compound the risk of muscle loss Practical and proactive steps you can take to avoid losing independence as you age How chronic under-fueling disrupts women's metabolism, recovery, and resilience in midlife The value of VO₂ max beyond cardiovascular fitness How grip strength functions as an early indicator of overall strength and neurological health The importance of daily, low-level movement for stabilizing blood sugar, cardiovascular health, and body weight How inadequate or disrupted sleep can negate the benefits of training programs Connect with Cynthia Thurlow Follow on X, Instagram & LinkedIn Check out Cynthia's website Submit your questions to support@cynthiathurlow.com Join other like-minded women in a supportive, nurturing community: The Midlife Pause/Cynthia Thurlow Cynthia's Menopause Gut Book is on presale now! Cynthia's Intermittent Fasting Transformation Book The Midlife Pause Supplement Line Connect with Debra Atkinson On her website The Flipping 50 Podcast On Social Media: @flipping50tv
Are your children suffering from sports injuries? Mark's guest is a pediatric sports medicine specialist who gives excellent advice in this episode. Middle School and High School injuries are due to overuse. Perhaps you as a parent can spot potential injuries before they occur. Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.
After 17 years, the American College of Sports Medicine has updated its strength training guidelines… and the truth is shocking:
Dentistry is full of big-ticket purchases, but many clinicians overlook the most expensive and valuable “equipment” they own: their body. In this episode, Kirk Behrendt sits down with Dr. Uche Odiatu to reframe the equipment conversation around physical health, and to lay out practical, sustainable habits that protect performance over a long career. You'll learn why sleep and light exposure are foundational, how consistency beats extremes, and which nutrition “bottlenecks” can quietly undermine energy, cognition, and longevity—so you can keep practicing (and living) well for decades. listen to Episode 1035 of The Best Practices Show!Main Takeaways:The most valuable and expensive piece of equipment in a dental practice is the dentist's physical body, and it requires intentional investment.By midlife, poor sleep and food habits stop being sustainable and begin to show up as chronic pain, fatigue, and reduced capacity to perform.Sleep is the bedrock habit because it impacts hormones, recovery, cognition, and long-term health outcomes.Getting outside shortly after waking (even briefly) supports circadian rhythm, daytime energy, and deeper sleep later that night.Consistency with simple habits beats “all-or-nothing” health plans that are hard to sustain long term.Nutrition basics matter more than supplements, and common nutrient shortfalls can impact decision-making and overall health.Clinicians can model wellness-based leadership by taking care of themselves and guiding patients with a broader view of health.Snippets:00:00 The “most valuable and expensive equipment” in dentistry.02:00 Why dentists invest in tech but not their physical health.04:10 The health cost of delaying self-care until “later.”05:30 Why the conversation should focus on solutions, not just problems.06:10 Sleep as the foundation habit.07:10 The “six doctors”: exercise, nutrition, sleep, stress, light, and hormesis.08:20 Morning light exposure and why going outside matters.11:00 Kirk's daily weighted-vest walking routine.14:20 Why consistency beats extreme routines.17:10 Nutrition bottlenecks: choline, omega-3s, vitamin D, and fiber.21:40 Practical fiber sources and simplifying food choices.23:10 A simple daily baseline: sleep, light, eggs, and avocado.26:00 What dentists can notice about health by observing faces and mouths.27:10 Kirk's “Nordstrom suit” moment and making a change.28:10 Dr. Uche's “gray face” moment and rethinking work habits.Guest Bio/Guest Resources:Dr. Uche Odiatu has a DMD (Doctor of Dental Medicine). He is a professional member of the ACSM (American College of Sports Medicine), a Certified Personal Trainer NSCA (National Strength & Conditioning Association), and the Canadian Association of Fitness Professionals (canfitpro). He is the co-author of The Miracle of Health and has lectured in Canada, the USA, the Caribbean, the UK, and Europe. He is an invited guest on over 400 TV and radio shows, from ABC 20/20, Canada CTV AM, Breakfast TV, to Magic Sunday Drum FM in Texas. This high-energy healthcare professional has done over 450 lectures in seven countries over the last 15 years.Instagram: https://www.instagram.com/fitspeakers/Website: https://www.druche.com/More Helpful Links for a Better Practice & a Better Life:The Best Practices Show: https://www.actdental.com/podcast/Best Practices Association: https://www.actdental.com/bpaUpcoming Events & Workshops: https://www.actdental.com/events/Smile Source: https://www.smilesource.com/Subscribe on Apple Podcasts: https://podcasts.apple.comSubscribe on Spotify: https://open.spotify.com
On this episode of the Sports Medicine Primer Series, host Dr. Zainab Shirazi, MD, is joined by Dr. Stan Herring, MD, FAMSSM, to discuss the treatment and management of an injured high school football player. The goal of this ongoing series is to provide an audio study aid for anyone pursuing a career as a sports medicine physician and to prepare them for a sports medicine fellowship. A Founder of AMSSM, Dr. Herring is a co-founder of the Sports Institute at UW Medicine, where he serves as senior medical advisor, and he also serves as co-medical director of the UW Medicine Sports Concussion Program. He is also co-medical director of UW Medicine Orthopedic Health and Sports Medicine and is a former team physician for the Seattle Mariners and the Seattle Seahawks. Dr. Herring's practice focuses on the diagnosis and management of neurological and musculoskeletal injuries, particularly focusing on spinal disorders in active people and athletes, as well as sports-related concussions. Dr. Shirazi is an Attending Physician at Women's Health, Sports & Performance (WHSP) Medical in Brighton, MA, and a dual board-certified physician in Sports Medicine and Physical Medicine & Rehabilitation. She has a passion for advancing the health and performance of female athletes and specializes in the non-operative management of musculoskeletal and sports-related injuries, providing comprehensive care for athletes of all ages and abilities. Resources: Sport Concussion Assessment Tool 6 (SCAT6): https://bjsm.bmj.com/content/57/11/622 Sport Concussion Office Assessment Tool 6 (SCOAT6): https://bjsm.bmj.com/content/57/11/651
The importance of the mind-body connection in Sports Medicine is well-established and continues to be a hot topic of study and conversation. This connection between psychological and physical is especially noted with ACL injuries, surgery, and rehabilitation. Dr. Brian M. Devitt, MD, PhD from UPMC Sports Surgery Clinic in Dublin, Ireland joins us to discuss his team's work examining psychological readiness and return to play rates in elite versus nonelite athletes. One might assume that the elite athlete, perhaps with more personal athletic identity and rehab resources would outperform the nonelite athlete, but does that actually play out?
Fitness mit M.A.R.K. — Dein Nackt Gut Aussehen Podcast übers Abnehmen, Muskelaufbau und Motivation
Die meisten Ratgeber beruhen auf Stress-Forschung aus den 90ern – und wurden für 30-Jährige geschrieben. Kein Wunder, dass die alte Cortisol-Formel ab 40 nicht mehr zu funktionieren scheint.In dieser Folge erfährst Du, wie chronischer Stress Dein Hormonsystem ab 40 aus dem Takt bringt, warum Östrogen und Testosteron als natürliche Stresspuffer schwächer werden – und warum die gleiche Belastung Dich mit 45 messbar härter trifft als mit 30.Dazu bekommst Du fünf evidenzbasierte Werkzeuge, die Du noch diese Woche umsetzen kannst. Eins davon kostet Dich fünf Minuten am Tag. Eins brauchst Du nur, wenn Du in der Mittagspause ohnehin essen willst. Und eins ist das am besten dokumentierte Anti-Stress-Werkzeug der letzten zehn Jahre – obwohl es fast nie in Stress-Ratgebern auftaucht.Diese Folge ist für Dich, wenn Du wissen willst, was sich an Deinem Körper ab 40 wirklich verändert – und was konkret dagegen hilft.____________*WERBUNG: Infos zum Werbepartner dieser Folge und allen weiteren Werbepartnern findest Du hier.____________
Police training is designed to push limits — physically, mentally and emotionally. But when the culture of grit outpaces medical awareness and safeguards, the consequences can be irreversible. In this episode of the Policing Matters podcast, host Jim Dudley and fitness expert Traci Tauferner examine the risks embedded in high-intensity academy training, the gaps in concussion recognition and the responsibility leaders carry to protect recruits without compromising readiness. From hydration and baseline testing to psychological support and instructor training, the episode delivers a practical look at how academies can better identify risk and intervene before a routine drill becomes a tragedy. About our guest Traci Tauferner is an athletic trainer and strength and conditioning specialist with extensive experience supporting law enforcement, military and public safety personnel. As the director of industrial and tactical medicine at Advanced Physical Therapy and Sports Medicine, she works with agencies and municipalities to design and implement programs focused on injury prevention, performance optimization and recovery. Her approach blends clinical expertise with real-world operational demands, helping departments build healthier, more resilient workforces. Connect with her: LinkedIn Instagram About our sponsor This episode of the Policing Matters podcast is sponsored by OfficerStore. Learn more about getting the gear you need at prices you can afford by visiting OfficerStore.com.
What exactly is runner's knee? How do athletes like Stephen Curry deal with patellofemoral syndrome? Listen to our latest podcast as Dr Brian Feeley and Dr Drew Lansdown break it all down.
The American College of Sports Medicine just published its first updated position stand on resistance training since 2009, and the findings challenge some the most widely held assumptions in the fitness industry. In Episode 13, hosts Rachel Chonko and Luke Carlson break down the ACSM's new paper which synthesized more than 30,000 studies published over the last 15 years. The conclusions are clarifying with direct implications for how health clubs program, communicate and coach. This Episode Covers: - What the science actually says drives muscle growth (and what doesn't — including some widely held assumptions about load and frequency). - Why progressive overload is the single most important variable in any strength training program. - The case for minimal effective dose: how three exercises, once or twice per week, can produce meaningful results. - What the safety data says about resistance training for older adults — and why the risk perception doesn't match the evidence.
In this episode, Vanessa breaks down the fasting mimicking diet (FMD) — including the exact calories, macros, and protein intake used in the research — and compares it to higher-protein fat loss approaches like protein-sparing modified fasting (PSMF) days.
Dr. Spencer Nadolsky and Dr. Karl Nadolsky sit down with Dr. Stuart Phillips, senior author on the newly updated American College of Sports Medicine position stand on resistance training, to break down what 137 systematic reviews and over 30,000 participants actually tell us about building muscle, getting stronger, and improving function across the lifespan. The last version of these guidelines was published in 2009 and the science has come a long way, even if the fundamentals have not. In this episode they cover why lifting weights twice a week is already getting most of the available benefit and three times is better but not by as much as you think, why the hypertrophy rep range is far broader than the classic 8 to 12 and what that actually means for your training, why getting stronger still requires lifting heavy things regardless of what anyone tells you, how power training is about moving with intentional velocity and why it matters more as you age than most people realize, why periodization showed no statistically significant advantage over non-periodized programs in the systematic review and what that means in practice, why eccentrically biased training produces slightly better muscle growth but is an optimization tool not a fundamental one, why time under tension does not have the evidence base people think it does, why blood flow restriction remains a niche tool rather than a strategic advantage, and why the best workout is simply the one you will actually show up and do consistently. The Docs Who Lift podcast distills and simplifies the complexities of exercise, medicine, and weight loss. Subscribe so you never miss an episode. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
Discover Leslie Bennett’s insights on being an exceptional athletic training preceptor, her passion for the profession, and advice for aspiring ATCs. Q: What makes you an exceptional preceptor, and why do students consistently choose to learn from you? A: I've been practicing since 2009, having graduated from TXST and then joining MHH. I became a preceptor in 2016 when I joined UST, where I now serve as the Director of Sports Medicine and Senior Woman Administrator. This allows students to experience both the hospital and university aspects of my work. I aim to teach them how to advocate for the athletic training profession. Q: What is your favorite aspect of being a preceptor? A: My favorite part is the daily interaction with students. I enjoy watching them grow throughout their athletic training careers, from start to finish. It keeps me active and engaged, always moving and lifting equipment alongside them. Q: What inspired you to become an athletic trainer (AT)? A: My journey began in high school; I was a student seeking an activity before basketball season. I’ve always wanted to work in healthcare as a “giver at heart,” specifically with an active and motivated population. What truly drives me is the opportunity to inspire athletes to become their best selves. I also focus on imparting life lessons and common sense, helping them mature into adults. Q: Amanii, what made Leslie a good preceptor for you? A: Amanii stated that my personality made me a good preceptor. I am very welcoming and provide a safe space for students to be hands-on and make mistakes. I added that I aim to give students ample opportunities to practice and learn before they are on their own, without overwhelming them. Q: Amanii, is there anything Leslie could have done better to help you? A: Amanii reflected that she is quiet and reserved and needs more one-on-one discussions to talk through things. She also acknowledged that she needs to be more verbal and proactive in asking for help when she needs it. Q: What is the most valuable lesson you’ve learned as a preceptor from students? A: Teaching and conducting skills checks with students is the best thing I’ve learned as a preceptor. This process keeps me fresh, on my toes, and ensures I stay current with the latest practices and information in the field. Q: Jackson, what are the differences in expectations between your first and second-year students? A: As Jackson, I believes in a hands-on approach from the start, as students might not get such opportunities at other sites. First-year students receive more guided practice; for example, I’d bring them along for a concussion evaluation to observe and ask questions. By their second year, I expect them to lead first-year students and attempt any evaluation, acting as mentors. Q: What are your general expectations for first-year and second-year students? A: For first-year students, my main expectation is willingness to work. If you’re comfortable with ankle evaluations, I’ll provide those opportunities, and we’ll build from there. For second-year students, I expect them to mentor first-years and be ready to attempt any evaluation. I added three expectations: be ready for anything, be a sponge, and be flexible. I also stressed not to complain about menial tasks, as students are paying to be prepared. Q: How do you balance your professional and personal life as an athletic trainer? A: As a single AT, my life is simpler, though my lifestyle might be a reason I’m single. Initially, it was challenging to advocate for myself, but now I set strict boundaries with athletes and coaches. My Athletic Director is supportive and helps enforce these boundaries. Jackson emphasizes communication with all parties, especially his wife, using a shared calendar to manage busier seasons and ensure understanding. Q: What are the unique aspects of navigating the athletic training profession as a Black woman? A: As a female AT, I must be prepared to stand my ground against those who doubt my capabilities. It’s important to demonstrate competence in all aspects of the job. Being a Black female AT also means representing diversity and understanding the unique challenges some athletes face, allowing me to advocate for those who cannot. A downside is that my directness can sometimes be perceived as abrasive. It was tougher initially, and challenging moments still occur, but it’s crucial to document incidents as perception is key. Q: What advice would you give to aspiring athletic trainers starting their first year as ATCs? A: I advise networking extensively, as your current professional pool is small. Seek out mentors and build relationships with people at different levels and settings. Attend medical timeouts and district meetings to connect with others. Never assume you know everything; it’s okay to say, “I don’t know, but I will find out.” Contact Us Jeremy Jackson Benjamin Stephenson Layci Harrison Mark Knoblauch Ashlyne Elliott Leslie Bennett Sponsor List Frio Hydration – Superior Hydration products. Xothrm – Best heating pad available – Use “SMB” or email info@xothrm.com and mention the Sports Medicine Broadcast. Donate and get some swag (like Patreon but for the school) HOIST – No matter your reason for dehydration, DRINK HOIST MedBridge Education – Use “TheSMB” to save some money, be entered in a drawing for a second year free, and support the podcast. Marc Pro – Use “THESMB” to recover better. Athletic Dry Needling – Save up to $100 when registering through our link.
Platelet-rich plasma (PRP) injections do not have formal FDA approval for specific clinical indications. PRP is regulated as an autologous blood product and is used "off-label" in clinical practice. However, there is substantial clinical evidence supporting its use for certain dental surgeries and musculoskeletal conditions, particularly lateral epicondylitis, knee osteoarthritis, and plantar fasciitis. The American Medical Society for Sports Medicine notes that PRP is primarily used to treat tendinopathies and osteoarthritis, though clinical efficacy results remain mixed due to variability in PRP formulations and preparation methods. As of now, there are no FDA approved uses for PRP for gynecologic use, although there has been some evidence of possible benefit in vulvar dermatoses and possiblt ovarian function enhancement. But what about its use in the vagina for sexual pleasure? Injecting into the anterior vaginal wall (around the famed G-Spot location) is nothing new. Over a decade ago, a TV show introduced the masses to the “G-Spot amplication” shot which injected collagen to that area. But there was no data for this. Well, we are back to this idea in a new RCT in the Green Journal. Can PRP light up the vaginal fires of pleasure? Listen in for details. 1. Clarke, Bayley MD; Gaddam, Neha MD; Garcia, Bobby MD; Iglesia, Cheryl B. MD; Podolsky, Robert PhD; Dieter, Alexis A. MD. Vaginal Injection of Platelet-Rich Plasma for Sexual Function: A Randomized Controlled Trial. Obstetrics & Gynecology ():10.1097/AOG.0000000000006256, March 19, 2026. | DOI: 10.1097/AOG.00000000000062562. Finnoff JT, Awan TM, Borg-Stein J, et a American Medical Society for Sports Medicine Position Statement: Principles for the Responsible Use of Regenerative Medicine in Sports Medicine. Clinical Journal of Sport Medicine : Official Journal of the Canadian Academy of Sport Medicine. 2021. 3. Alsousou J, Ali A, Willett K, Harrison P. The Role of Platelet-Rich Plasma in Tissue Regeneration.Platelets. 2012.
In this episode, we break down the newly updated 2026 strength training guidelines from the American College of Sports Medicine — the first major update in nearly two decades, backed by extensive research and real-world application.If you've ever felt confused by sets, reps, or conflicting advice online, this episode simplifies it all. We walk through what's actually changed, what matters most, and how to apply these guidelines whether you're a beginner, runner, busy parent, or just looking to get stronger in a sustainable way.You'll learn:Why consistency matters more than perfectionWhy you don't need to train to failure to see resultsHow 2–3 strength sessions per week can be enoughWhat “10+ sets per muscle group per week” really meansHow to tailor your training for strength, muscle growth, or powerWhy you don't need fancy equipment to build strengthThis episode is all about cutting through the noise and helping you train with more clarity, confidence, and purpose — using science-backed principles that actually fit into real life.Whether you're lifting at home, in the gym, or balancing strength work with running, you'll walk away with actionable takeaways you can start using immediately.
Dr. Christle Guevarra, DO, MS, specializes in Family Medicine, Sports Medicine, Obesity Medicine, Nutrition, and is a former powerlifting champion. Today on the show we discuss: the truth about GLP-1s and why weight loss isn't just willpower, how food noise works and what happens in your brain when it disappears, the right way to use GLP-1s without losing muscle or energy, why most people fail fat loss and how to fix it, how to build a sustainable routine with training, nutrition, and realistic expectations, and the deeper mindset work required to create lasting transformation beyond the scale and much more. Today's sponsor: Ax3 Get 20% off your first order of Ax3: https://ax3.life and use code "Doug" at checkout ⚠ WELLNESS DISCLAIMER ⚠ Please be advised; the topics related to health and mental health in my content are for informational, discussion, and entertainment purposes only. The content is not intended to be a substitute for professional advice, diagnosis, or treatment. Always seek the advice of your health or mental health professional or other qualified health provider with any questions you may have regarding your current condition. Never disregard professional advice or delay in seeking it because of something you have heard from your favorite creator, on social media, or shared within content you've consumed. If you are in crisis or you think you may have an emergency, call your doctor or 911 immediately. If you do not have a health professional who is able to assist you, use these resources to find help: Emergency Medical Services—911 If the situation is potentially life-threatening, get immediate emergency assistance by calling 911, available 24 hours a day. National Suicide Prevention Lifeline, 1-800-273-TALK (8255) or https://suicidepreventionlifeline.org. SAMHSA addiction and mental health treatment Referral Helpline, 1-877-SAMHSA7 (1-877-726-4727) and https://www.samhsa.gov Learn more about your ad choices. Visit megaphone.fm/adchoices
The Warriors have had bad luck this season with injuries with Moses Moody's patellar tendon rupture occurring this week. Listen to our podcast as Dr Brian Feeley break down patellar tendon ruptures with some ACL recovery thrown in as well.
Andrea breaks down the latest update from the American College of Sports Medicine, unpacking what the newest research actually says about strength training, muscle growth, and how to make fitness more effective and realistic for everyday life. She walks through the biggest changes, from rep ranges and training frequency to recovery and volume, and explains how these updated guidelines make building strength more accessible no matter your age, experience, or available equipment. Andrea helps cut through outdated fitness myths and focus on what truly works so they can train smarter, stay consistent, and see real results.Make Fit Simple Podcast is sponsored by KION. Go to Getkion.com/simple for 20% off. Join my newsletter! https://www.deliciouslyfitnhealthy.com/emlsFollow the Make Fit Simple Podcast@MakeFitSimplePodcastHave a suggestion for a topic click HEREHave a suggestion for a guest click HERENEW! Leave a question for Andrea HERE on SpeakPipe!Follow Andrea on Instagram@deliciouslyfitnhealthy@dfh.training.picsTraining & Coachinghttps://www.deliciouslyfitnhealthy.com/linksVisit Andrea's Websitewww.deliciouslyfitnhealthy.comProduced by Light On Creative Productions
Ready to take your home workouts to the next level? In this episode of “Random Fit,” hosts Wendy Batts, and Ken Miller, dive deep into the essentials for building YOUR perfect home fitness space—no gym membership required! Whether you're looking to optimize for limited space, tight budgets, or simply want to avoid equipment gathering dust, you'll get actionable advice from two industry experts with years of hands-on experience. What's Inside This Episode: · Real conversations about what actually belongs in a home gym—no more wasted money on unused gear! · Insider tips on selecting must-have items, from foam rollers and mini bands to cable machines, adjustable dumbbells, TRX, stability balls, and more. · Smart strategies for tailoring your home gym to YOUR needs, goals, budget, and space. · Pro advice for choosing equipment that lasts—not just what's trendy. · Why safety, organization, and floor choices matter for home workout success. · How to keep your fitness space clean, versatile, and motivating for everyone in your household. Key Takeaways: ✔️ The right equipment for mobility, strength, and recovery ✔️ How to shop smart whether you're a beginner or a pro✔️ Creative hacks for small spaces and busy lifestyles ✔️ Real stories from personal training clients (including pro athletes!) ✔️ Expert-approved brands and tools for lasting resultsIf you're tired of clutter and confusion—and want a fun, practical guide to home fitness—this episode is for you. Don't forget to LIKE, SUBSCRIBE, and hit the bell for more expert fitness talk, gear recommendations, and game-changing wellness tips! Episode References:National Academy of Sports Medicine. (n.d.). The ultimate guide to building a home gym. NASM Blog. Retrieved October 9, 2025, from https://blog.nasm.org/home-gym-essentials Sutton, B. (2022, September 12). Kettlebell basics: A beginner's guide. NASM Blog. https://blog.nasm.org/kettlebell-basics-a-beginners-guide If you like what you just consumed, leave us a 5-star review, and share this episode with a friend to help grow our NASM health and wellness community! The content shared in this podcast is solely for educational and entertainment purposes. It is not intended to be a substitute for professional advice, diagnosis, or treatment. Always seek out the guidance of your healthcare provider or other qualified professional. Any opinions expressed by guests and hosts are their own and do not necessarily reflect the views of NASM. Introducing NASM One, the membership for trainers and coaches. For just $35/mo., get unlimited access to over 300 continuing education courses, 50% off additional certifications and specializations, EDGE Trainer Pro all-in-one coaching app to grow your business, unlimited exam attempts and select waived fees. Stay on top of your game and ahead of the curve as a fitness professional with NASM One. Click here to learn more. https://bit.ly/4ddsgrm
March 17, 2026: Your daily rundown of health and wellness news, in under 5 minutes. Today's top stories: American College of Sports Medicine updates resistance training guidelines for first time in 17 years, emphasizing consistency over perfect programming Peloton introduces Commercial Series bike and treadmill for gyms, pairing Precor-engineered hardware with instructor-led classes shipping late 2026 Costco partners with Sesame and IVI RMA to offer fertility care with up to 80% savings on medications, addressing one in six Americans facing infertility Today's episode is brought to you by AIIR — a modern communications and experiential agency for health, wellness, fitness, and performance brands. From earned media to events and creator-led campaigns, AIIR helps companies sharpen their story, earn attention, and build trust that compounds. Visit https://aiir.agency to learn more. More from Fitt: Fitt Insider breaks down the convergence of fitness, wellness, and healthcare — and what it means for business, culture, and capital. Subscribe to our newsletter → insider.fitt.co/subscribe Work with our recruiting firm → https://talent.fitt.co/ Follow us on Instagram → https://www.instagram.com/fittinsider/ Follow us on LinkedIn → linkedin.com/company/fittinsider Reach out → insider@fitt.co
In most sports, men compete against men and women compete against women. That is generally considered fair, because men are faster, more powerful and have greater endurance.But there is an ongoing controversy about transgender women - people who were born male and now identify as women. Is it fair for them to compete in the women's sport category or do they have an advantage?A study in the British Journal of Sports Medicine recently added to the debate with an analysis that found the strength and fitness of transgender women is “comparable” with that of women.More or Less looks into the research to explain what it does, and does not, say.Contributors:Professor Alun Williams, Manchester Metropolitan UniversityCredits:Presenter: Charlotte McDonald Reporter: Tom Colls Production co-ordinator: Brenda Brown Sound Mix: Gareth Jones Editor: Richard Vadon
Real Men Connect with Dr. Joe Martin - Christian Men Podcast
Brad "Dr. Brad" Bellard is a faith-based purpose & performance strategist for men. He helps high-achieving professional men pivot from an unfulfilling career to pursue their calling, so they can live a life of significance and impact. Through his coaching program, best-selling book, and online show, he equips men with the clarity and confidence needed to go from stuck in their current work, to fulfilling their God-given purpose and greatest impact on the world. Dr. Brad is also a double-boarded Sports Medicine physician. He has worked with multiple professional teams including serving as an assistant team doctor for the NBA Dallas Mavericks. He's married to his beautiful high-school sweetheart, Cristina, and together they have 3 children. To find out more about Dr. Brad and the work he does with men, check out his website at http://www.DrBradMd.com ---------------------- Talk with Dr. Joe 1-on-1: Are you tired and stuck? Want to go to get your faith, marriage, family, career and finances back on track? Then maybe it's time you got a coach. Every CHAMPION has one. Schedule an appointment to chat with Dr. Joe. He takes on only a few Breakthrough Calls each week. The call is FREE, but slots are limited to ONE call only. NO RESCHEDULES. Just click on the link below and select the BREAKTHROUGH CALL option to set up an appointment: http://TalkwithDrJoe.com If no slots are available, please check back in a week. Also join us on: Online Podcast Community (on Station): https://station.page/realmen Facebook: @realdrjoemartin YouTube: http://www.RealMenTraining.com Instagram: @realdrjoemartin Twitter: @professormartin Website: https://RealMenConnect.com