Podcasts about Phase

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    Best podcasts about Phase

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    Latest podcast episodes about Phase

    Effortless English Podcast | Learn English with AJ Hoge

    You're in a meeting. Your manager asks, "What do you think?" Your heart races. You KNOW the answer — in your language. But in English? Your mind goes blank. You freeze. This is NOT a language problem. It's a brain problem. And I'm going to show you the exact 90-day system that fixes it permanently.

    Warburg Podcast
    Umschichten oder abwarten? So viel Risiko steckt aktuell im Portfolio

    Warburg Podcast

    Play Episode Listen Later Mar 12, 2026 22:12


    Auch bei YouTube.Der Krieg zwischen dem Iran und den USA sowie Israel sorgt für erhebliche Unruhe an den globalen Energiemärkten. Innerhalb kürzester Zeit kletterte der Preis für Öl der Sorte Brent von 60 auf 120 US-Dollar. Doch handelt es sich hierbei um einen kurzfristigen Schock oder müssen sich Anlegende auf eine dauerhafte Phase der Instabilität einstellen?"Das hängt davon ab, wie sich Amerika entscheidet, wie sich der Krieg entwickelt", meint Dr. Christian Jasperneite, Chief Investment Officer bei M.M.Warburg & CO. "Und ich bin mir nicht sicher, ob Trump da einen Masterplan hat, weil die Aussagen diesbezüglich ein bisschen inkonsistent sind."Wie er mit dieser Unsicherheit umgeht, welche Länder und Sektoren besonders vom Krieg betroffen sind und wie er auf Inflation und Geldpolitik blickt, berichtet er im Gespräch mit Carsten Klude, Chefvolkswirt bei M.M.Warburg & CO.Die Themen im Überblick:00:00 Krieg zwischen Iran, Israel & USA02:51 Ausblick auf die Energiemärkte05:36 Märkte in Deutschland & Europa07:51 Inflation & Geldpolitik in USA & Europa11:33 Aktienmärkte13:49 Sektoren: Energie & Rüstung16:35 Anleihen: Sicherer Hafen?17:49 Was gibt Sicherheit im Portfolio?20:29 Was hat Warburg gemacht?► LinkedIn► Instagram► WebsiteMusik: "Hard Boiled" Kevin MacLeod (incompetech.com)Licensed under Creative Commons: By Attribution 4.0 Licensehttp://creativecommons.org/licenses/by/4.0/

    BioSpace
    Prasad Out at FDA, Lawmaker Takes Action on Rare Disease Rejections and a Spate of Obesity Data

    BioSpace

    Play Episode Listen Later Mar 11, 2026 28:12


    After Friday's news that Center for Biologics Evaluation & Research Chief Vinay Prasad will leave the FDA—again—at the end of April, stocks for several rare disease drug developers popped. UniQure, in particular, was up 51% in premarket trading on Monday. Prasad in a meeting last Thursday with select journalists called the biotech's Huntington's treatment AMT-130 a “failed” therapy, according to STAT News. Shares of Replimune and REGENXBIO—which have suffered rejections during the past year—also rose.One person who is not impressed with the plethora of rare disease drug rejections of late—H.C. Wainwright said in a note Tuesday that there have been at least five cell and gene therapies they believe could have been approved under prior FDA officials—is Wisconsin Senator Ron Johnson. Tuesday, Bloomberg News reported that Johnson has launched an investigation into these recent denials.Johnson called the FDA's request that uniQure conduct a sham surgery-controlled trial of AMT-130 “bureaucratic idiocy,” according to the publication. Meanwhile, uniQure and the FDA appear to be on different pages regarding the design of this prospective trial, with uniQure Chief Medical Officer Walid Abi-Saab referring to a 10-12 hour surgery during which [burr] holes would be drilled in patients' skulls and Prasad claiming on a media call last week that it would require only “one to three nicks in the scalp.”In other news, no episode of The Weekly would be complete without our weekly weight loss segment. Roche and Zealand Pharma's amylin analog fell short of Eli Lilly's rival candidate eloralintide; AbbVie reported what analysts called “competitive” results, with its amylin analog eliciting nearly 10% weight loss at 13 weeks in a Phase 1 trial; and Regeneron touted a much-needed Phase 3 win for Hansoh-partnered dual GLP-1/GIPR agonist olatorepatide in China. Beyond data, Novo Nordisk and Hims & Hers are together again, with Novo striking a deal to sell its injectable and oral GLP-1 medicines through the telehealth provider.Elsewhere on the business side of biopharma, experts are reporting a cut-throat atmosphere behind doors on the M&A front as the supply of companies available to buy dwindles.

    ring frei!
    47 – mit Sarah Mohs von Berlin Werbefrei und Heinrich Strößenreuther vom Baumentscheid

    ring frei!

    Play Episode Listen Later Mar 11, 2026 57:50


    Allianzen für die Stadtgestaltung: Baumentscheid und Berlin Werbefrei zu GastWas passiert, wenn sich die Köpfe hinter drei der prägendsten Berliner Volksinitiativen an einen Tisch setzen?In dieser besonderen Folge von Ring frei! begrüßen wir zwei Schwergewichte der Berliner Zivilgesellschaft: Sarah Mohs von der Initiative Berlin Werbefrei und Heinrich Strößenreuther, den „Serien-Initiator“, der nach dem Fahrradentscheid 2015 zuletzt den Baumentscheid zum Erfolg geführt hat. Gemeinsam ziehen wir Bilanz: Während die Initiative Berlin autofrei mehr als drei Jahre auf den Sieg vor dem Landesverfassungsgericht aufgrund dessen Nichtbesetzung warten musste, haben Sarah und Heinrich ganz unterschiedliche Erfahrungen mit dem Berliner Senat gemacht: Der Werbeentscheid, bereits 2017 gegründet musste noch länger warten – der Baumentscheid hingegen war in Rekordzeit erfolgreich. Daher sind aktuell nur die ersten beiden Initiativen in der Phase der massiven Mobilisierung: Beide benötigen 240,000 Unterschriften bis zum 08. Mai. 2026.Die Schwerpunkte dieser Episode:Der „Baum-Frieden“: Heinrich Strößenreuther erklärt, wie es dem Baumentscheid durch eine radikal non-konfrontative Strategie gelang, die zweite Sammelphase zu überspringen und ein „120-Prozent-Gesetz“ direkt mit Schwarz-Rot auszuhandeln.Sieben Jahre im Wartesaal: Sarah Mohs schildert den steinigen Weg von Berlin Werbefrei. Seit 2017 kämpft die Initiative gegen juristische Sabotage, verschleppte Prüfungen und „Märchenrechnungen“ des Senats über entgangene Werbeeinnahmen.Die Kosten-Lüge: Wir vergleichen die Zahlen. Warum regt sich der Senat über 31-48 Millionen Euro Kosten für weniger Werbung auf, während er gleichzeitig vergleichbare Summen Steuergeld in ein ineffizientes und nicht kostendeckendes Anwohnerparken buttert?Mut zum „Verbot“: Heinrich Strößenreuther plädiert für eine offensive Rhetorik und ein kraftvolles Bekenntnis zu kluger Ordnungspolitik. Statt sich als „Verbotspartei“ abstempeln zu lassen, sollten wir klar benennen, was wir verbieten wollen: Den „Vorstadt-Schmarotzern“ das Recht zu nehmen, die Innenstadt mit Abgasen, Lärm, Verkehrsgewalt und Flächenfraß zu belasten.Endspurt 2026: Warum die kommenden sieben Wochen entscheidend sind und wir jede Hand brauchen, um die nötigen Unterschriften für ein lebenswerteres Berlin zu sammeln.Diese Folge ist ein Deep Dive in die Werkzeugkiste der direkten Demokratie. Wir diskutieren über Macht, strategisches Nicht-Gendern, die Psychologie von Wahlplakaten und die Vision einer Stadt, die wieder den Menschen gehört – ohne blinkende Screens und Blechlawinen.Hört rein, lasst euch inspirieren und ab auf die Straße zum Sammeln! Berlins Zukunft ist autofrei – und dit is ooch jut so!Neugierig geworden? Dann bitte hier einsteigen!  Ring frei! live im Radio: Ihr könnt uns ⁠⁠auf DAB+ und per Livestream⁠⁠⁠⁠ hören, wir senden immer am zweiten Dienstag im Monat um 18 Uhr live aus der Raumfahrtagentur in Berlin Wedding.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Jetzt Fördermitglied in unserem neuen Verein werden!⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Für alle, die uns finanziell unterstützen möchten, gibt es neben einmaligen Spenden ab sofort auch die Möglichkeit, Fördermitglied des Vereins zu werden.Mitmachen!Wir freuen uns jetzt besonders über neue motivierte Menschen, die beim Unterschriftensammeln unterstützen möchten!!! NEUE WEBSITE & CROWDFUNDING !!⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Website Verkehrsentscheid Berlin⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Bluesky⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Instagram⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Mastodon⁠Alle Infos zu den Initiativen und wie ihr helfen könnt:⁠https://www.verkehrsentscheid.de/https://berlin-werbefrei.de/https://www.baumentscheid.de/

    Der Itzehoe Eagles Podcast
    "... Ich höre auf" - Adlerschnack mit Luca Merkel

    Der Itzehoe Eagles Podcast

    Play Episode Listen Later Mar 11, 2026 60:25


    Was geht eigentlich in einem Basketballer vor, wenn der Körper plötzlich nicht mehr mitspielt?

    Haimspiel.de
    Sharkbite Ep 134 – Die letzten Prozente

    Haimspiel.de

    Play Episode Listen Later Mar 11, 2026 72:34


    Die letzten ProzenteBei den Haien fehlen aktuell die letzten Prozente. Die Hauptrunde ist für die Haie gelaufen, bevor Sie zu Ende ist – im positiven Sinne. Aber auch bei uns fehlen in einigen Momenten die letzten Prozent und man merkt das die Saison lang war und aktuell Kräfte für die Playoffs gesammelt werden.Kurz vor der Aufnahme gab es die Info der Vertragsverlängerung von Janne Juvonen. Logisch, dass wir damit den Sharkbite dann auch beginnen.Playoffs in denen die U20 und U17 schon mittendrin stecken. Die U20 braucht gegen die Eisbären alle drei Spiele, um den Einzug ins Halbfinale zu feiern. Dort geht es ab Samstag gegen Ligaprimus Mannheim im Best of 5 um den Platz im Finale.Der U17 reichten zwei Spiele gegen Kaufbeuren und auch dort beginnt ab Samstag das Halbfinale. Das kleine rheinische Derby gegen den KEV steht an.Bei den Damen gab es eine Niederlage im Derby gegen die DEG.Nur drei Punkte für die Haie in den Partien gegen Augsburg und Berlin, sowie in Mannheim. Man merkt dann eben doch, wenn man gegen Teams spielt, für die es um noch mehr geht als nur „drei weitere Punkte“, sondern eben auch um Platzierungen.Wobei die Niederlage in Mannheim nochmal eine andere „Qualität“ hatte. Wir empfehlen nochmal in die Pressekonferenz zu hören – oder auf Youtube zu schauen – wenn man sehen will, wie angefressen Jalonen war.Die Tabelle zwei Spieltage vor Ende hat noch nicht alle Entscheidungen preisgegeben und daher gucken wir genau auf diese neuralgischen Punkte. Freitag könnte schon alles entschieden sein, aber so ein letzter Spieltag ohne Spannung wäre doch auch nichts.Dazu gibt es News der letzten Woche, unter anderem mit der Verkündung der sehr guten Magenta-Zahlen der DEL.Da wir zu Beginn schon über Juvonen gesprochen haben, gab es in der letzten Woche nur noch das Fanvillage über das es sich zu reden lohnt. Auch da waren wir aktiv.Ergibt gibt es drei Spiele in den kommenden fünf Tagen. Mit den Panthern aus Augsburg und den Eisbären aus Berlin erwarten die Haie zwei Teams, für die es noch um einiges geht in der LANXESSarena. Das Auswärtsspiel in Mannheim ist dann der DEL-Klassiker und vermutlich so kurz vor den Playoffs ein Spiel, um nochmal dem Gegner zu zeigen, was man kann.Junge junge, auch das Tippspiel geht in die heiße Phase, vorne noch alles möglich und dann gibt es den Ausklang aus der Folge. Auch da irgendwie fehlen die letzten Prozente…Wo könnt ihr uns überall folgen und liken? Wie erreicht Ihr uns? Wo findet Ihr uns?Folgt dem Sharkbite gerne auf Bluesky⁠, ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Instagram⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠, ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Facebook ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ kommt in den WhatsApp Kanal und abonniert die Podcastfeeds beim Anbieter Eurer Wahl. 00:00 Einleitung & Juvonen05:30 Junghaie12:05 Das vergangene Wochenende35:20 Das 20. DEL-Wochenende56:50 Haie-News60:30 Vorschau68:40 Tippspiel & Ausleitung

    Thoughtful Money with Adam Taggart
    We're Entering The "Death Spiral" Phase Of Currency Collapse | John Rubino

    Thoughtful Money with Adam Taggart

    Play Episode Listen Later Mar 10, 2026 59:36


    REGISTER FOR THOUGHTFUL MONEY'S SPRING ONLINE CONFERENCE AT THE 'LAST CHANCE TO SAVE' DISCOUNT PRICE at https://www.thoughtfulmoney.com/conferenceHistory repeats. And we've seen time and time again over the ages how monetary systems collapse.Monetary analyst John Rubino thinks we're now entering the "death spiral" phase of the world's major fiat currencies, due to immense amount of debt obligations nations are now burdened with.What come next?Watch this video to find out.#money #fiatmoney #currencycollapse _____________________________________________ Thoughtful Money LLC is a Registered Investment Advisor Promoter.We produce educational content geared for the individual investor. It's important to note that this content is NOT investment advice, individual or otherwise, nor should be construed as such.We recommend that most investors, especially if inexperienced, should consider benefiting from the direction and guidance of a qualified financial advisor registered with the U.S. Securities and Exchange Commission (SEC) or state securities regulators who can develop & implement a personalized financial plan based on a customer's unique goals, needs & risk tolerance.IMPORTANT NOTE: There are risks associated with investing in securities.Investing in stocks, bonds, exchange traded funds, mutual funds, money market funds, and other types of securities involve risk of loss. Loss of principal is possible. Some high risk investments may use leverage, which will accentuate gains & losses. Foreign investing involves special risks, including a greater volatility and political, economic and currency risks and differences in accounting methods.A security's or a firm's past investment performance is not a guarantee or predictor of future investment performance.Thoughtful Money and the Thoughtful Money logo are trademarks of Thoughtful Money LLC.Copyright © 2026 Thoughtful Money LLC. All rights reserved.

    A Flair For VIP Events
    73. The Realities of Mid-Career in Events - The Most Misunderstood Phase in an Event Career Pt. 2

    A Flair For VIP Events

    Play Episode Listen Later Mar 10, 2026 29:33


    In Part Two, we get real about the stuff mid-career event professionals don't usually say out loud. The comparison spiral, the financial realities, the identity shift when you realize you don't want to be the person you were ten years ago anymore. And the quiet decision point where your career either drifts or becomes intentional. This is for anyone whose event industry ambition feels different lately.P.S. You may notice a small change to the podcast name in the coming months! Just to align with the three topics I now cover - major events, VIP management AND event careers!Get a copy of my FREEBIES:Where to Look for Olympics Jobs and WhenA clear breakdown of where Olympic-related roles are advertised, how far in advance hiring happens, and what to focus on at different stages of the Olympic cycle.⁠⁠⁠https://iconicevents.thrivecart.com/work-at-the-olympics⁠⁠⁠21 Places to Find Iconic Event OpportunitiesA super simple and straightforward resource to help you uncover where opportunities for your dream events exist⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://iconicevents.thrivecart.com/21-places-iconic-events-opportunities⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠The Iconic Events Career Change GuideGet this powerful, no fluff (and not so basic) guide for event pros craving more. Whether you're shifting sectors, re-entering after a break, or finally ready to go after big events, this guide will help you get started: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://iconicevents.thrivecart.com/the-iconic-events-career-evolution-guide/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠If you're serious about working at iconic events and you want to go deeper, Inside Iconic Events starts soon. It's my 8 week program designed to help you create a career in major events. Enrollment is open now!⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://lauralloydevents.com/inside-iconic-events⁠⁠⁠⁠⁠Support Laura:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.buymeacoffee.com/laurayarblloyd⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Connect with Laura:LinkedIn: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.linkedin.com/in/laurayarbroughlloyd⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Website: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.lauralloydevents.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Instagram: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.instagram.com/lauralloydevents⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ and ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.instagram.com/aflairforvipevents⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Youtube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.youtube.com/@laurayarbroughlloyd⁠⁠⁠⁠⁠Tiktok:⁠⁠⁠⁠ https://www.tiktok.com/@lauralloydevents

    Paul's Security Weekly
    Breaking in with CrashFix, supply chain security, and CMMC phase 1 - David Zendzian, Anna Pham, Jacob Horne - ESW #449

    Paul's Security Weekly

    Play Episode Listen Later Mar 9, 2026 94:33


    Interview with Anna Pham Breaking in with ClickFix: Anatomy of a modern endpoint attack Cybersecurity company Huntress just published a report on a new ClickFix variant they've discovered, which they've dubbed CrashFix. This technique was developed by KongTuke to serve as the primary lure within a new custom malicious browser extension also created by the group. In short, the team observed the threat actors using KongTuke's malicious browser extension to display a fake security warning, claiming the browser had “stopped abnormally” and prompting users to run a “scan” to remediate the threats. Upon “running the scan,” the user is presented with a fake “Security issues detected” alert and instructed to manually “fix” the issue by opening the Windows Run dialog, pasting from their clipboard, and pressing Enter. The malicious extension silently copies a PowerShell command to the clipboard, disguised as a legitimate repair command. From there, they execute the malicious command. Segment Resources: BLOG - Dissecting CrashFix: KongTuke's New Toy Interview with David Zendzian Continuous compliance and real security lifecycle management Supply chain attacks are not just on the rise; attackers are learning from the past, making these attacks even more effective and dangerous than before. It was just over a month ago when the Shai-Hulud attack first impacted NPM packages, forcing enterprises around the world into lockdown. While only 187 packages were compromised in that initial incident, it served as a wake-up call for many: an accurate inventory of systems is good, but a clear, real-time Software Bill of Materials (SBOM) for applications is non-negotiable. In this world of manifest based infrastructure and container based applications with (real) "devsecops", the dream of continuous upgrades of OS/Runtime/Stack/App and App Dependencies is very mature and there are solid examples of companies and federal entities managing this at scale without thousands of teams and people. Segment Resources: BLOG - Supply Chain Security: How accurate SBOMs can deliver proactive threat mitigation Interview with Jacob Horne CMMC Phase 1 Enforcement — What the November 10 Deadline Means for the Defense Supply Chain With the upcoming CMMC Phase 1 enforcement on November 10, cybersecurity teams across the defense and federal supply chain are facing new compliance requirements that directly affect contract eligibility and data-protection standards. Jacob Horne, Chief Cybersecurity Evangelist at Summit 7, can break down what this milestone means for enterprise security leaders, MSPs/MSSPs, and contractors preparing for audits. Visit https://www.securityweekly.com/esw for all the latest episodes! Show Notes: https://securityweekly.com/esw-449

    The Cool Fireman Podcast
    Firefighter Burnout: The Stress Nobody Talks About

    The Cool Fireman Podcast

    Play Episode Listen Later Mar 9, 2026 69:46


    In this episode of The Cool Fireman Podcast, the crew kicks things off with some big Patreon news: the Engineer Tier officially hit 10 subscribers, which means Phase 1 is live and the first Wheel of Names giveaway is underway. Congrats to Simon Gray, who takes home the first box of firefighter goodies.The guys also share a heartfelt Moment of Silence honoring firefighters recently lost, including Lt. Robert “Dean” Clary, who passed away from occupational cancer, along with other recent line-of-duty losses. It's a powerful reminder of the risks firefighters face both on and off the fireground.The main topic centers around burnout — what it looks like, how it builds, and how firefighters can recognize it before it takes a bigger toll. The conversation touches on stress at work, life at home, mental exhaustion, faith, family, and the importance of having healthy outlets and strong people in your corner.The episode wraps with snail mail, listener feedback, and more discussion around training, priorities, and the reality of balancing fire service life.In this episode:Patreon giveaway officially beginsSimon Gray wins the first Wheel of Names boxMoment of Silence for recent firefighter lossesBurnout in the fire serviceStress, mental fatigue, and healthy coping outletsListener comments and training discussionSupport the podcast:

    Enterprise Security Weekly (Audio)
    Breaking in with CrashFix, supply chain security, and CMMC phase 1 - David Zendzian, Anna Pham, Jacob Horne - ESW #449

    Enterprise Security Weekly (Audio)

    Play Episode Listen Later Mar 9, 2026 94:33


    Interview with Anna Pham Breaking in with ClickFix: Anatomy of a modern endpoint attack Cybersecurity company Huntress just published a report on a new ClickFix variant they've discovered, which they've dubbed CrashFix. This technique was developed by KongTuke to serve as the primary lure within a new custom malicious browser extension also created by the group. In short, the team observed the threat actors using KongTuke's malicious browser extension to display a fake security warning, claiming the browser had "stopped abnormally" and prompting users to run a "scan" to remediate the threats. Upon "running the scan," the user is presented with a fake "Security issues detected" alert and instructed to manually "fix" the issue by opening the Windows Run dialog, pasting from their clipboard, and pressing Enter. The malicious extension silently copies a PowerShell command to the clipboard, disguised as a legitimate repair command. From there, they execute the malicious command. Segment Resources: BLOG - Dissecting CrashFix: KongTuke's New Toy Interview with David Zendzian Continuous compliance and real security lifecycle management Supply chain attacks are not just on the rise; attackers are learning from the past, making these attacks even more effective and dangerous than before. It was just over a month ago when the Shai-Hulud attack first impacted NPM packages, forcing enterprises around the world into lockdown. While only 187 packages were compromised in that initial incident, it served as a wake-up call for many: an accurate inventory of systems is good, but a clear, real-time Software Bill of Materials (SBOM) for applications is non-negotiable. In this world of manifest based infrastructure and container based applications with (real) "devsecops", the dream of continuous upgrades of OS/Runtime/Stack/App and App Dependencies is very mature and there are solid examples of companies and federal entities managing this at scale without thousands of teams and people. Segment Resources: BLOG - Supply Chain Security: How accurate SBOMs can deliver proactive threat mitigation Interview with Jacob Horne CMMC Phase 1 Enforcement — What the November 10 Deadline Means for the Defense Supply Chain With the upcoming CMMC Phase 1 enforcement on November 10, cybersecurity teams across the defense and federal supply chain are facing new compliance requirements that directly affect contract eligibility and data-protection standards. Jacob Horne, Chief Cybersecurity Evangelist at Summit 7, can break down what this milestone means for enterprise security leaders, MSPs/MSSPs, and contractors preparing for audits. Visit https://www.securityweekly.com/esw for all the latest episodes! Show Notes: https://securityweekly.com/esw-449

    CruxCasts
    Chesapeake Gold (TSXV:CKG) - Imminent Tech Results Could Unlock Massive Precious Metal Project

    CruxCasts

    Play Episode Listen Later Mar 9, 2026 27:11


    Interview with Jean-Paul Tsotsos, CEO & Justin Black, CMO, Chesapeake GoldOur previous interview: https://www.cruxinvestor.com/posts/chesapeake-gold-tsxvckg-proprietary-oxidation-process-could-help-unlock-15t-in-stranded-gold-6963Recording date: 4th March 2026Chesapeake Gold Corp. is advancing Metates, one of the world's largest undeveloped precious metals deposits, through a proprietary oxidative leach technology that has solved a four-decade metallurgical challenge while slashing capital requirements by 90%.The Metates deposit in Mexico hosts over 500 million ounces of silver (ranked first globally) and 19 million ounces of gold (18th globally). Discovered in 1980, the project's refractory ore—where precious metals are locked within sulfide minerals resistant to conventional processing—prevented successful development by multiple major mining companies despite decades of attempts.Chesapeake's breakthrough came through acquiring and advancing oxidative leach technology originally developed at Hycroft over nearly a decade with $50 million in combined investment. The technology operates at ambient temperature in heap leach pads, eliminating the need for expensive autoclaves, extensive water infrastructure, and on-site power generation.The economic transformation is dramatic. Chesapeake's initial 2016 prefeasibility study using conventional pressure oxidation envisioned a $3.5 billion capital expenditure for a 90,000 ton-per-day operation requiring a desalination plant, water pipelines, and power plant. The oxidative leach approach reduces capex to $360 million for a 15,000 ton-per-day starter operation while improving gold recovery from 33% to 74% and silver recovery from 35% to 50%. Phase 3 testing shows further improvements, with results expected in Q1-Q2 2026.Beyond Metates, Chesapeake is pursuing a technology licensing strategy targeting 200+ identified refractory deposits globally. Three companies are currently conducting amenability testing, with results expected within two months. These third-party implementations serve dual purposes: validating the technology at operating sites ahead of Metates development while creating revenue potential through royalties or equity positions.Mexico's regulatory environment has improved significantly under President Sheinbaum, with two-thirds of 170 backlogged permits resolved. The prefeasibility study for Metates is underway, with completion dependent on regulatory progress rather than remaining technical uncertainties.Learn more: https://www.cruxinvestor.com/companies/chesapeake-goldSign up for Crux Investor: https://cruxinvestor.com

    CruxCasts
    Visionary Copper & Gold (TSXV:VCG) - 2026 Resource Growth & Confidence Plan at Point Leamington

    CruxCasts

    Play Episode Listen Later Mar 9, 2026 19:19


    Interview with Max Porterfield, President & CEO of Visionary Copper & Gold Inc.Our previous interview: https://www.cruxinvestor.com/posts/visionary-copper-gold-mines-tsxvvgc-pitch-perfect-9001Recording date: 4th March 2026Visionary Copper & Gold is focused on unlocking the value of Point Leamington, a polymetallic VMS deposit in Newfoundland, Canada, that holds over 20 million tonnes of gold, silver, copper, and zinc mineralisation and has seen no modern exploration since 2004. The company's current Phase 1 drilling programme is delivering early results that management believes confirm the deposit's potential to grow significantly from its existing resource base.The deposit's existing pit-constrained resource contains approximately 500,000 ounces of gold, 8 million ounces of silver, 170 million pounds of copper, and 700 million pounds of zinc. Gold currently accounts for approximately 55% of contained metal value. However, the most consequential development from recent drilling is not within the known resource but within the footwall beneath it.Visionary has confirmed a new copper zone, named Kraken, in the footwall to Point Leamington's main massive sulphide lens. This type of structure is a defining characteristic of the world's largest VMS deposits. At Ming in Newfoundland, a copper stringer zone sits below the main lens. At Flin Flon Bay in Manitoba, the copper-rich footwall accompanies a zinc-dominant main horizon. The first Kraken hole returned a 76-metre interval at 0.45% copper and a second intersection of 23 metres at 1.5% copper which are consistent with the early-stage definition of footwall zones that have materially expanded comparable systems.Alongside the Kraken results, the company has extended the confirmed strike length of Point Leamington to over one kilometre. This is an important structural distinction. Most large VMS systems — including Ming, Lalor, and 777 in Manitoba — have strike extents of 200 to 250 metres, with their tonnage coming primarily from depth. The small number of VMS systems with significantly longer strike extents, such as Kidd Creek and Flin Flon, have produced some of the largest total resource outcomes globally. Point Leamington's confirmed kilometre-plus strike places it in this rarer category.The development plan for 2026 is clear and sequenced. Phase 1 drilling will continue stepping out around the Kraken intersection. Phase 2 will follow after ground conditions improve, targeting resource upgrades and further Kraken delineation. A two-phase metallurgical programme will collect data to support economic studies, and the company is targeting an updated resource estimate and a preliminary economic assessment within the year.Beyond Newfoundland, Visionary holds the Rainbow/Pine Bay copper asset in Manitoba. An advanced exploration permit application is currently under review, and an Environmental Act licence for full-scale production is being prepared. The asset sits within trucking distance of three concentrators and approximately 30 minutes from a rail line linked to Canada's proposed Churchill port export corridor — a route that has attracted attention from federal and provincial governments in the context of critical mineral supply chain security.The entire Eastern Canada portfolio was assembled in 2016 for $1.1 million. With gold above $3,000 per ounce and structural copper deficits widening, Visionary is positioned at an early stage of what could be a significant resource expansion cycle at one of Canada's most overlooked large-scale VMS systems.View Visionary Copper & Gold's company profile: https://www.cruxinvestor.com/companies/visionary-copper-gold-minesSign up for Crux Investor: https://cruxinvestor.com

    Paul's Security Weekly TV
    Breaking in with CrashFix, supply chain security, and CMMC phase 1 - Anna Pham, David Zendzian, Jacob Horne - ESW #449

    Paul's Security Weekly TV

    Play Episode Listen Later Mar 9, 2026 94:33


    Interview with Anna Pham Breaking in with ClickFix: Anatomy of a modern endpoint attack Cybersecurity company Huntress just published a report on a new ClickFix variant they've discovered, which they've dubbed CrashFix. This technique was developed by KongTuke to serve as the primary lure within a new custom malicious browser extension also created by the group. In short, the team observed the threat actors using KongTuke's malicious browser extension to display a fake security warning, claiming the browser had "stopped abnormally" and prompting users to run a "scan" to remediate the threats. Upon "running the scan," the user is presented with a fake "Security issues detected" alert and instructed to manually "fix" the issue by opening the Windows Run dialog, pasting from their clipboard, and pressing Enter. The malicious extension silently copies a PowerShell command to the clipboard, disguised as a legitimate repair command. From there, they execute the malicious command. Segment Resources: BLOG - Dissecting CrashFix: KongTuke's New Toy Interview with David Zendzian Continuous compliance and real security lifecycle management Supply chain attacks are not just on the rise; attackers are learning from the past, making these attacks even more effective and dangerous than before. It was just over a month ago when the Shai-Hulud attack first impacted NPM packages, forcing enterprises around the world into lockdown. While only 187 packages were compromised in that initial incident, it served as a wake-up call for many: an accurate inventory of systems is good, but a clear, real-time Software Bill of Materials (SBOM) for applications is non-negotiable. In this world of manifest based infrastructure and container based applications with (real) "devsecops", the dream of continuous upgrades of OS/Runtime/Stack/App and App Dependencies is very mature and there are solid examples of companies and federal entities managing this at scale without thousands of teams and people. Segment Resources: BLOG - Supply Chain Security: How accurate SBOMs can deliver proactive threat mitigation Interview with Jacob Horne CMMC Phase 1 Enforcement — What the November 10 Deadline Means for the Defense Supply Chain With the upcoming CMMC Phase 1 enforcement on November 10, cybersecurity teams across the defense and federal supply chain are facing new compliance requirements that directly affect contract eligibility and data-protection standards. Jacob Horne, Chief Cybersecurity Evangelist at Summit 7, can break down what this milestone means for enterprise security leaders, MSPs/MSSPs, and contractors preparing for audits. Show Notes: https://securityweekly.com/esw-449

    Pharma and BioTech Daily
    Navigating Regulatory Shifts Amid Biotech Breakthroughs

    Pharma and BioTech Daily

    Play Episode Listen Later Mar 9, 2026 5:40


    Good morning from Pharma Daily: the podcast that brings you the most important developments in the pharmaceutical and biotech world. Today, we delve into a series of significant events and trends shaping the industry landscape, offering insight into the dynamic interplay between scientific innovation, regulatory challenges, and strategic growth.Starting with the recent departure of Vinay Prasad from the U.S. Food and Drug Administration, particularly from his role as director of the Center for Biologics Evaluation and Research (CBER). Prasad's tenure, though brief, left an indelible mark characterized by controversy and debate over regulatory decisions. His leadership coincided with significant advancements in biologics and gene editing technologies, like CRISPR, highlighting the complexities in balancing innovation with safety standards. Under Prasad's guidance, the FDA faced challenges in navigating these rapid advancements while maintaining rigorous oversight to ensure that new therapies are both effective and safe for public use. Prasad's resignation signals potential shifts in regulatory philosophy at CBER. The biotech industry is watching closely to see how new leadership will influence ongoing and future evaluations of biologics. The change presents an opportunity to reassess how regulatory bodies can better adapt to scientific advancements while ensuring that patient safety remains paramount. The issues faced during Prasad's tenure underscore the need for transparent decision-making and open communication with stakeholders, which are vital for maintaining trust in regulatory processes.Meanwhile, Pfizer has made a strategic entry into the Chinese obesity market with the approval of a GLP-1 drug developed alongside Sciwind Biosciences. This approval represents not only a significant step for Pfizer but also underscores a broader global focus on obesity management. The efficacy of GLP-1 receptor agonists in weight regulation has opened up new market opportunities, highlighting the growing importance of metabolic health solutions in addressing public health challenges.In other news, Johnson & Johnson's Tecvayli-Darzalex combination therapy has received its third national priority recognition from the FDA for treating multiple myeloma. This recognition reflects promising Phase 3 trial results and underscores the critical role of innovative combination therapies in improving outcomes for complex hematologic malignancies. The success of such therapies illustrates how targeted approaches can significantly enhance treatment efficacy and patient quality of life.Strategic acquisitions continue to reshape industry dynamics. Servier's $2.5 billion acquisition of Day One Biopharmaceuticals aims to strengthen its rare cancer portfolio, including a promising glioma drug, Ojemda. This move highlights Servier's commitment to addressing unmet needs in pediatric oncology and rare diseases, emphasizing a broader industry trend towards focusing on niche therapeutic areas with high potential impact.Regulatory activities are gaining momentum as well, with the FDA set to end a nine-month hiatus in advisory committee meetings by reviewing AstraZeneca's oral selective estrogen receptor degrader Truqa. As AstraZeneca seeks to enhance its oncology pipeline, this review signals ongoing innovation in hormone-based cancer therapies and reflects a renewed emphasis on bringing novel treatments to market efficiently.Additionally, Glenmark Pharmaceuticals has achieved a significant milestone with FDA approval for its generic version of GSK's asthma inhaler Flovent. This development exemplifies efforts to improve access to respiratory treatments by providing cost-effective alternatives to branded medications, potentially reducing healthcare costs while enhancing patient access.On an international scale, Taiwan has announced a substantial investment plan aimed at bolstering its drugSupport the show

    Enterprise Security Weekly (Video)
    Breaking in with CrashFix, supply chain security, and CMMC phase 1 - Anna Pham, David Zendzian, Jacob Horne - ESW #449

    Enterprise Security Weekly (Video)

    Play Episode Listen Later Mar 9, 2026 94:33


    Interview with Anna Pham Breaking in with ClickFix: Anatomy of a modern endpoint attack Cybersecurity company Huntress just published a report on a new ClickFix variant they've discovered, which they've dubbed CrashFix. This technique was developed by KongTuke to serve as the primary lure within a new custom malicious browser extension also created by the group. In short, the team observed the threat actors using KongTuke's malicious browser extension to display a fake security warning, claiming the browser had "stopped abnormally" and prompting users to run a "scan" to remediate the threats. Upon "running the scan," the user is presented with a fake "Security issues detected" alert and instructed to manually "fix" the issue by opening the Windows Run dialog, pasting from their clipboard, and pressing Enter. The malicious extension silently copies a PowerShell command to the clipboard, disguised as a legitimate repair command. From there, they execute the malicious command. Segment Resources: BLOG - Dissecting CrashFix: KongTuke's New Toy Interview with David Zendzian Continuous compliance and real security lifecycle management Supply chain attacks are not just on the rise; attackers are learning from the past, making these attacks even more effective and dangerous than before. It was just over a month ago when the Shai-Hulud attack first impacted NPM packages, forcing enterprises around the world into lockdown. While only 187 packages were compromised in that initial incident, it served as a wake-up call for many: an accurate inventory of systems is good, but a clear, real-time Software Bill of Materials (SBOM) for applications is non-negotiable. In this world of manifest based infrastructure and container based applications with (real) "devsecops", the dream of continuous upgrades of OS/Runtime/Stack/App and App Dependencies is very mature and there are solid examples of companies and federal entities managing this at scale without thousands of teams and people. Segment Resources: BLOG - Supply Chain Security: How accurate SBOMs can deliver proactive threat mitigation Interview with Jacob Horne CMMC Phase 1 Enforcement — What the November 10 Deadline Means for the Defense Supply Chain With the upcoming CMMC Phase 1 enforcement on November 10, cybersecurity teams across the defense and federal supply chain are facing new compliance requirements that directly affect contract eligibility and data-protection standards. Jacob Horne, Chief Cybersecurity Evangelist at Summit 7, can break down what this milestone means for enterprise security leaders, MSPs/MSSPs, and contractors preparing for audits. Show Notes: https://securityweekly.com/esw-449

    EV News Daily - Electric Car Podcast
    BRIEFLY: VW ID.Golf, EV Vans, 400-Stall Charger Site & more | 07 Mar 2026

    EV News Daily - Electric Car Podcast

    Play Episode Listen Later Mar 8, 2026 4:16


    It's EV News Briefly for Saturday 07 March 2026, everything you need to know in less than 5 minutes if you haven't got time for the full show.Patreon supporters fund this show, get the episodes ad free, as soon as they're ready and are part of the EV News Daily Community. You can be like them by clicking here: https://www.patreon.com/EVNewsDailyVW SHOWS WORKERS NINTH-GEN GOLF PLANVolkswagen has given Wolfsburg workers a first look at the ninth-generation Golf, expected to carry the ID Golf name and built on VW Group's new Scalable Systems Platform (SSP). From summer 2027, current combustion-engine Golf production shifts to Mexico, freeing Wolfsburg to retool for the ID Golf and an electric VW T-Roc successor.STELLANTIS CUTS ELECTRIC VAN PRICES TO DIESEL LEVELStellantis Pro One is running a European campaign until end of June that matches the purchase price of eight battery-electric vans to their diesel equivalents across compact and mid-size segments. The offer directly closes gaps such as the €7,150 difference between the Opel Combo Cargo Electric and its diesel counterpart, testing whether price parity alone will push fleets to commit.TESLA EYES 400-STALL SUPERCHARGER SITE IN YERMOTesla is planning a 400-stall V4 Supercharger station in Yermo, California on Interstate 15 between Los Angeles and Las Vegas, which would more than double the current record of 164 stalls. The site would be built in six phases as part of a wider retail hub called Eddie World 2, with Phase 1 delivering 72 stalls breaking ground in 2026.UBER BACKS POD HOME CHARGING SUBSCRIPTION FOR DRIVERSUber has partnered with Pod in the UK to offer drivers a home EV charger subscription for £25 per month over three years, with no upfront cost, a lifetime warranty, and potential cash rewards of up to £170 a year through smart charging. The offer arrives as Uber expands its Uber Electric category to eight new UK cities including Birmingham, Manchester, and Leeds.BYD SURGES IN GERMANY AND UKBYD registrations surged 1,550% year-on-year in Germany in February to 3,053 vehicles, while also rising 83% in the UK to 2,154 units and tripling in Spain to 3,003 registrations. The gains come as BYD ramps up its first European plant in Hungary, built partly to sidestep EU tariffs on Chinese-imported EVs imposed in October 2024.NIO SHIFTS EUROPE TO DISTRIBUTORSNio is overhauling its European operations by switching from direct sales to a distributor-led model in Germany, the Netherlands, and Sweden, while retaining direct sales only in Norway. The restructure, moving from a country-led to a function-led organisation, has already seen Nio Germany general manager David Sultzer step down.MILENCE OPENS 400 KW TRUCK CHARGING HUB IN GHENTMilence, backed by Volvo Group, Daimler Truck, and Traton, has opened a 400 kW HGV charging hub at the Volvo Trucks plant in Ghent, its fourth Belgian site, positioned on the TEN-T North Sea–Mediterranean freight corridor. A second phase will add Megawatt Charging System infrastructure, targeting charge times of 30 to 45 minutes for large HGV batteries.UK ADDED TO EU PLANS FOR EV PRODUCTION LIMITSThe European Commission's Industrial Accelerator Act (IAA) will open EU manufacturing subsidies to up to 40 "trusted partner" nations including the UK and Japan, following lobbying by UK business secretary Peter Kyle after fears that Nissan's Sunderland plant could close under earlier exclusionary proposals. The IAA also targets lifting manufacturing's share of EU GDP from 14.3% to 20% by 2035, though US firms are expected to be excluded due to American public procurement restrictions.ETHIOPIA'S EV IMPORT SHARE JUMPS AFTER ICE BANAfter Ethiopia banned ICE vehicle imports in 2024 and cut EV import duties, EVs rose from under 1% to around 6% of all vehicle imports, surpassing the reported global average of roughly 4%. The government is driving electrification as energy sovereignty, aided by low electricity costs of around $0.10 per kWh and a tiered tariff structure that exempts domestically assembled EV kits from import tax entirely.ORBÁN'S BATTERY BET HITS A DOWNTURNHungary has attracted approximately €26 billion in foreign EV battery investment, mainly from South Korean and Chinese manufacturers, but battery output has fallen during a prolonged sector downturn weeks before the April 12 national election. The strategy faces additional political pressure after a news investigation into health and safety violations at Samsung SDI's factory undermined the narrative around foreign-capital-led industrialisation.QUEENSLAND PUSHES UNDER-16 BAN FOR E-MOBILITYA Queensland parliamentary inquiry has tabled 28 recommendations including a ban on under-16s riding e-bikes and personal mobility devices, prompted by 12 e-mobility deaths and over 6,300 emergency department presentations in the state last year. Key proposals also include requiring at least a learner car licence to ride, cutting footpath speed limits to 10 km/h, and reclassifying any device capable of exceeding 25 km/h as a motorcycle.

    The U.S. Navy History Podcast
    U.S. Navy Involvement in Operation Epic Fury

    The U.S. Navy History Podcast

    Play Episode Listen Later Mar 8, 2026 106:54


    In this episode, Dale and Christophe break down the U.S. Navy's role in Operation Epic Fury — the massive American military campaign launched against Iran on February 28, 2026. From the decades of tension that set the stage, to the opening Tomahawk salvo, the systematic destruction of the Iranian Navy, and the debut of revolutionary new drone technology, this episode covers the full naval picture of one of the most significant military operations in a generation.Note: Everything discussed in this episode reflects what has been publicly reported as of early March 2026. Details may be updated or corrected as more information becomes available. Some cost figures are modeled estimates from think tanks, not confirmed Pentagon data. Operational details — including submarine deployments, munitions counts, and targeting specifics — reflect only what officials have chosen to disclose publicly.The episode opens with the 45-year history of U.S.-Iran tensions that made Operation Epic Fury inevitable — from the 1979 hostage crisis, to the IRGC's systematic harassment of commercial shipping in the Strait of Hormuz, to the 2019 tanker attacks, to Operation Midnight Hammer in June 2025, when the U.S. struck Iran's nuclear facilities using B-2 stealth bombers and submarine-launched Tomahawks.From there, Dale and Christophe walk through the full naval order of battle assembled for Epic Fury — the USS Abraham Lincoln and USS Gerald R. Ford carrier strike groups, fourteen Arleigh Burke-class destroyers, three littoral combat ships, and an undisclosed number of submarines operating across the Arabian Sea, the Persian Gulf, and the eastern Mediterranean — and explain why the geographic positioning of each asset was as strategic as the assets themselves.The episode then dives into the opening Tomahawk campaign, the systematic destruction of the Iranian Navy — including the first sinking of an enemy vessel by U.S. torpedo since World War II — and Iran's massive retaliatory barrage of 500+ ballistic missiles and 2,000+ drones in the first four days of the war. Dale and Christoph examine how the Navy's Aegis missile defense systems held the line, and why the sustainability of interceptor stockpiles is one of the most pressing strategic questions hanging over the operation.The second half of the episode covers the combat debut of LUCAS — the $35,000 drone reverse-engineered from Iran's own Shahed-136 — and the critical but largely invisible role of the EA-18G Growler in clearing the electronic path over Iranian airspace. The episode closes with a hard look at the economics of the operation, the shift to Phase 2 targeting Iran's missile production industrial base, and what Operation Epic Fury reveals about the future of American sea power — including the vulnerabilities it has exposed along the way.Email us at usnavyhistorypodcast@gmail.com, find us on X at @USNHistoryPod, and join the conversation on our Discord server — https://discord.gg/bJ9Q5vXE. If you enjoyed this episode, tell a friend. It really helps.Fair winds and following seas.

    Mind Pump: Raw Fitness Truth
    2809 : Is Cardio Ideal For Fat Loss?

    Mind Pump: Raw Fitness Truth

    Play Episode Listen Later Mar 7, 2026 122:03


    Mind Pump Fit Tip: Cardio is Good for Fat Loss for 2-3 weeks. After that, it is a Waste of Time! (2:00) 1-minute cardio strategy. (21:58) I do not want to work out with you. (31:05) An INSANE commercial for fat-loss. (33:26) The Hydro Layer from Caldera is voted BEST for anti-aging by Men's Health Magazine. (41:05) Makeup for men. (42:36) PSA: Close your toilet seat before flushing. (45:56) Experience the difference of liposomal technology. (50:32) Homeschooled vs public school. (52:16) #ListenerCoaching call #1 – Megan from Alberta: Can an injury/imbalance on one end of the body negatively affect the complete opposite end of the body? (59:32) #ListenerCoaching call #2 – Nicole from AZ: How to make changes to work smarter, not harder. (1:25:48) #ListenerCoaching call #3 – Elissa from CA: What program to start with when recovering from anorexia and very sarcopenic? (1:39:46) #ListenerCoaching call #4 – Sara from CO: Is there a meaningful added benefit to deliberately training VO₂ max for longevity? (1:54:29) Related Links/Products Mentioned Get Coached by Mind Pump, live! Visit https://www.mplivecaller.com Visit Caldera Lab for an exclusive offer for Mind Pump listeners! **Code MINDPUMP20 for 20% off your first order of their best products. ** Experience the difference of Liposomal Technology. Use code MINDPUMP for 20% OFF everything. Visit: https://www.rhonutrition.com/discount/MINDPUMP March Spring Sale: Symmetry ($187), Prime ($107), Advanced Training Techniques Guide ($47) all for $147! (Over 50% off!) Visit: www.mapsmarch.com  Mind Pump Store Mind Pump #2655: Ten Cardio Hacks for Fat Loss, Health & Endurance Dorian Yates IG clip – Cardio tip Lilly's next-gen obesity drug delivers major weight loss in Phase 3 trial, but with many discontinuations A new picture of modern homeschooling in America Visit Dose for the exclusive offer for Mind Pump listeners! ** Code MINDPUMP for 25% off your first month of subscription. ** Mind Pump #2337: Is Hidden Household Mold Making You Sick? Mind Pump #2272: The Dangers of Heavy Metals & How to Flush From Your Body With Dr. Stephen Cabral Mind Pump #2652: How Undereating is Making You Fat & Unhealthy Mind Pump #2560: How to Break Free from Destructive Body Image Issues Mind Pump #2320: Throw Away the Scale! Mind Pump Podcast – YouTube Mind Pump Free Resources People Mentioned Dorian Yates (@thedorianyates) Instagram  Andrew Huberman, Ph.D. (@hubermanlab) Instagram Michael Israetel (@drmikeisraetel) Instagram Scott Sherr (@drscottsherr) Instagram Dr. William Seeds (@williamseedsmd) Instagram Dr. Stephen Cabral (@stephencabral) Instagram  

    The Other Side of Weight Loss
    Am I in Perimenopause? How to Tell What Phase You're In

    The Other Side of Weight Loss

    Play Episode Listen Later Mar 7, 2026 61:41


    If you had told me at 40 that perimenopause would turn my world upside down, I would've laughed. As a nutritionist specializing in women's hormones, I thought I had it handled. So why did I gain 15 pounds, lose my sleep, and feel like a stranger in my own body? In this episode, I'm sharing what I wish someone had told me before the storm hit. Why are so many intelligent, health-conscious women still confused about where they are in perimenopause? Why are we being offered antidepressants, birth control, or told we're "too young" instead of getting real answers? I break down the three phases of perimenopause in a way that finally makes sense, and explain how to know which phase you're actually in. Is it just progesterone? Is it estrogen? Do you really need HRT—and if so, when? I walk you through what's happening hormonally in each phase, why symptoms can feel so chaotic, and how to stop guessing your way through this decade-long transition.You don't have to suffer, and you definitely don't have to do this blindly! In this episode, we uncover: How to identify which phase of perimenopause you're in. Why progesterone drops first and what that means for sleep. What estrogen swings really feel like in midlife. When HRT might be supportive, and why timing matters so much. How thyroid, cortisol, and insulin interact with your changing hormones. If you've been wondering what on earth is happening to your body, this episode is your starting point. Let's make sense of your hormones!     Not sure if this is perimenopause — or just stress, aging, or something else? Perimenopause isn't one phase. It unfolds in stages — and each stage requires a different approach. This quiz will help you identify where you are in the transition and what hormonal shifts are most likely driving your symptoms. Take the quiz: What Phase of Perimenopause Are You In?     Sponsors Timeline is offering 20% off your first order of Mitopure. Go to timeline.com/HORMONE20 use coupon HORMONE20 and get 20% off your order. Coupon KM20 to get 20% off your order of Vitali Skin Care!     Are you in perimenopause or postmenopause and struggling with symptoms—but not getting the support you deserve? At Midlife Solutions, we specialize in hormone optimization for women in midlife. Our all-female clinical team offers telehealth care across all 50 U.S. states, with the ability to prescribe bioidentical estrogen, progesterone, testosterone, and thyroid medication.   Book your FREE Hormone Discovery Call Find out what's really driving your symptoms and what your next best steps are.   Visit the website: https://karenmartel.com   Shop the Midlife Solutions Store Over-the-counter bioidentical hormone creams and oils — no prescription needed. Including: • Progesterone • Estrogen Face Cream • Vaginal Moisturizer and more!   Take the Hormone Quiz Discover hidden hormone imbalances that could be driving your symptoms. Get personalized results (and yes, they may surprise you).   Women's Peptide Weight Loss Program Clinically guided, hormone-aware weight loss for midlife women.   Midlife RESET HRT Program A complete, supportive approach to hormone replacement therapy in midlife.   Your host: Karen Martel Certified Hormone Specialist, Transformational Nutrition Coach, & Weight Loss Expert   Karen's Facebook Karen's Instagram

    women shop phase perimenopause hrt mitopure transformational nutrition coach
    Health Freedom for Humanity Podcast
    Ep 224: The New Frontier of Biology: Water, Fields & Consciousness with Carlos Millán

    Health Freedom for Humanity Podcast

    Play Episode Listen Later Mar 6, 2026 141:03


    This podcast is made possible by our listeners and viewers. If this show has brought you value, you can support it by becoming a member of The Way Forward, our platform designed to help you find the health and freedom community (people, practitioners, schools, farms, and more) near you. Your membership directly supports the podcast and the work we do.Our bodies don't work like we think they do…Carlos Millán, a biologist and a mystic, questions some of the most foundational assumptions in modern biology. He proposes a framework that connects water, electricity, and consciousness, challenging the way the human body is typically understood. If the dominant model is incomplete, the implications extend far beyond the lab.We explore the world of consciousness through the lens of biology. We also revisit a nearly forgotten medical therapy that once treated severe infections by altering only a small portion of the blood. The results were documented, yet the explanation never fully aligned with the prevailing scientific model.At the center is a different way of seeing the body as an energetic ecosystem rather than a mechanical structure, and what that shift could mean for health, education, and the future of science.You'll Learn:[00:00] Introduction[08:05] The 100-year-old treatment that structured blood, not killed bacteria[18:57] What a dissolving mollusk egg reveals about blood, consciousness, and the placebo effect[33:29] A terminal cancer patient's 50% tumor reduction in one week[46:23] What your immune system is doing instead of killing bacteria[59:37]  How the body sustains itself without food, and the kidney's real role in that[01:07:09] How fluorescent light collapses a cell's electromagnetic field within seconds[01:34:59]  How lidocaine resets trauma stored in nervous tissue [01:43:31] When physical pain is a message, not a malfunction[01:58:55] Why nerves are conscious decision-makers, not passive wiresRelated The Way Forward Episodes: Quinton Marine Plasma with Robert Slovak | PodcastEp 172: The 4th Phase of Water: The Blueprint for Biological Energy with Dr. Gerald Pollack | PodcastResources Mentioned:Ultraviolet blood irradiation: Is it time to remember “the cure that time forgot”? By Ximing Wu et al. | ArticleFind more from Carlos:Carlos | WebsiteFind more from Alec:Alec Zeck | InstagramAlec Zeck | XThe Way Forward | InstagramThe Way Forward is Sponsored By:RMDY Academy & Collective: Homeopathy Made AccessibleHigh-quality remedies and training to support natural healing.Enroll hereExplore hereDr. Cowan's Garden helps you boost daily nutrient density with vegetable powders and clean, pasture-raised essentials. Shop now and use code: THEWAYFORWARD for 15% off your first order.

    The Business Brew
    Current Events - uniQure and the FDA

    The Business Brew

    Play Episode Listen Later Mar 6, 2026 95:14


    uniQure is a business that develops gene therapies. uniQure's AMT-130 is currently in the headlines. This podcast episode attempts to present the Huntington's Disease community's arguments for why the FDA should work collaboratively to design a palatable drug trial. Last week the FDA told uniQure that AMT-130 would be subject to a double blind, Phase 3, randomized controlled study. While the scientific basis for that request is sound in most cases, the Huntington's Disease community argues that path is overly burdensome; perhaps impossible. This episode cites:Dr. Sung - https://www.youtube.com/watch?si=VhMQaFAZRvQA5NRj&t=62&v=mwEEJ91LeJY&feature=youtu.beSr. Sarah Tabrizi - https://www.youtube.com/watch?v=wKj1JRfJBRE&t=356sDr. Ed Wild - https://www.spreaker.com/episode/uniqure-update-with-dr-ed-wild--67900959FDA papers - External Control Guidance https://www.fda.gov/media/122425/downloadUse of Bayesian Statistics - https://www.fda.gov/regulatory-information/search-fda-guidance-documents/use-bayesian-methodology-clinical-trials-drug-and-biological-productsSenate Committee on Aging - https://www.youtube.com/watch?v=yLm1SltbRxw&t=2702sSponsorship InformationThank you to ⁠⁠⁠⁠⁠⁠Trata⁠⁠⁠⁠⁠⁠ for sponsoring the show.If you're listening to this podcast, you'll like Trata. Trata is buyside to buyside conversations on individual stocks. Trata makes finding a bull or bear on any stock as easy as clicking two buttons. Over 125 funds globally contribute that collectively cover 2000+ tickers. Trata raised over $3mm coming out of Y Combinator. Before you would track 13Fs, now you can understand what funds are actually thinking. You can join as a lurker or you can join as a contributor and Trata will pay you hundreds of dollars per call. For a free trial, go to ⁠⁠⁠⁠⁠⁠trytrata.com/brew⁠⁠⁠⁠⁠⁠ OG Sponsor Shoutout!Thank you to ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Fiscal.ai⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ for sponsoring the show. DISCOUNT INFO: If you use the affiliate link ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠fiscal.ai/brew⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠, you will automatically get 2 weeks of Fiscal Pro for Free and if you find that you want to upgrade, my link will get you 15% off any paid plans. About ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Fiscal.ai⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Fiscal.ai⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ is the complete modern data terminal for global equities.The ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Fiscal.ai⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ platform combines a powerful user experience with all the financial data capabilities that professional investors need. Users get up to 20 years of historical financials for all stocks globally that they can easily chart, compare, or export into their own models. And unlike legacy data terminals where it can take hours or even days, ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Fiscal.ai⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠'s data is updated within minutes of earnings reports. ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Fiscal.ai⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ also tracks all the company-specific Segment & KPI data so you don't have to. Like to track Amazon's Cloud Revenue? They've got it.How about Spotify's premium subscribers? Or Google's quarterly paid clicks?They've got all of it.

    Materialism
    Episode 115: Phase Field Modeling

    Materialism

    Play Episode Listen Later Mar 6, 2026 40:20


    Many digital models use hard boundaries to simulate how materials change, but the real world is rarely that clean. Phase field modeling takes a more natural approach, capturing the gradual, messy transitions that actually occur. This makes it ideal for simulating things like crack growth or dendrite formation. Taylor sits down with Dr. Jake Bair, an assistant professor at Oklahoma State University to discuss how it works and the history behind it. Link of NISTs Phase Field Hub [HERE] This episode was Sponsored by California Nanotechnologies. Check out their upcoming SPS/FAST Experts Workshop in beautiful San Diego at the link. [HERE] This episode of the Materialism Podcast is sponsored by Momentum Transfer. Visit their website for more details about their measurement services. [LINK] The Materialism Podcast is sponsored by Materials Today, an Elsevier community dedicated to the creation and sharing of materials science knowledge and experience through their peer-reviewed journals, academic conferences, educational webinars, and more. Thanks to Kolobyte and Alphabot for letting us use their music in the show! If you have questions or feedback please send us emails at materialism.podcast@gmail.com or connect with us on social media: Instagram, Twitter. Materialism Team: Taylor Sparks, Andrew Falkowski, & Jared Duffy.

    Latent Space: The AI Engineer Podcast — CodeGen, Agents, Computer Vision, Data Science, AI UX and all things Software 3.0

    All speakers are announced at AIE EU, schedule coming soon. Join us there or in Miami with the renowned organizers of React Miami! Singapore CFP also open!We've called this out a few times over in AINews, but the overwhelming consensus in the Valley is that “the IDE is Dead”. In November it was just a gut feeling, but now we actually have data: even at the canonical “VSCode Fork” company, people are officially using more agents than tab autocomplete (the first wave of AI coding):Cursor has launched cloud agents for a few months now, and this specific launch is around Computer Use, which has come a long way since we first talked with Anthropic about it in 2024, and which Jonas productized as Autotab:We also take the opportunity to do a live demo, talk about slash commands and subagents, and the future of continual learning and personalized coding models, something that Sam previously worked on at New Computer. (The fact that both of these folks are top tier CEOs of their own startups that have now joined the insane talent density gathering at Cursor should also not be overlooked).Full Episode on YouTube!please like and subscribe!Timestamps00:00 Agentic Code Experiments00:53 Why Cloud Agents Matter02:08 Testing First Pillar03:36 Video Reviews Second Pillar04:29 Remote Control Third Pillar06:17 Meta Demos and Bug Repro13:36 Slash Commands and MCPs18:19 From Tab to Team Workflow31:41 Minimal Web UI Philosophy32:40 Why No File Editor34:38 Full Stack Cursor Debate36:34 Model Choice and Auto Routing38:34 Parallel Agents and Best Of N41:41 Subagents and Context Management44:48 Grind Mode and Throughput Future01:00:24 Cloud Agent Onboarding and MemoryTranscriptEP 77 - CURSOR - Audio version[00:00:00]Agentic Code ExperimentsSamantha: This is another experiment that we ran last year and didn't decide to ship at that time, but may come back to LM Judge, but one that was also agentic and could write code. So it wasn't just picking but also taking the learnings from two models or and models that it was looking at and writing a new diff.And what we found was that there were strengths to using models from different model providers as the base level of this process. Basically you could get almost like a synergistic output that was better than having a very unified like bottom model tier.Jonas: We think that over the coming months, the big unlock is not going to be one person with a model getting more done, like the water flowing faster and we'll be making the pipe much wider and so paralyzing more, whether that's swarms of agents or parallel agents, both of those are things that contribute to getting much more done in the same amount of time.Why Cloud Agents Matterswyx: This week, one of the biggest launches that Cursor's ever done is cloud agents. I think you, you had [00:01:00] cloud agents before, but this was like, you give cursor a computer, right? Yeah. So it's just basically they bought auto tab and then they repackaged it. Is that what's going on, or,Jonas: that's a big part of it.Yeah. Cloud agents already ran in their own computers, but they were sort of site reading code. Yeah. And those computers were not, they were like blank VMs typically that were not set up for the Devrel X for whatever repo the agents working on. One of the things that we talk about is if you put yourself in the model shoes and you were seeing tokens stream by and all you could do was cite read code and spit out tokens and hope that you had done the right thing,swyx: no chanceJonas: I'd be so bad.Like you obviously you need to run the code. And so that I think also is probably not that contrarian of a take, but no one has done that yet. And so giving the model the tools to onboard itself and then use full computer use end-to-end pixels in coordinates out and have the cloud computer with different apps in it is the big unlock that we've seen internally in terms of use usage of this going from, oh, we use it for little copy changes [00:02:00] to no.We're really like driving new features with this kind of new type of entech workflow. Alright, let's see it. Cool.Live Demo TourJonas: So this is what it looks like in cursor.com/agents. So this is one I kicked off a while ago. So on the left hand side is the chat. Very classic sort of agentic thing. The big new thing here is that the agent will test its changes.So you can see here it worked for half an hour. That is because it not only took time to write the tokens of code, it also took time to test them end to end. So it started Devrel servers iterate when needed. And so that's one part of it is like model works for longer and doesn't come back with a, I tried some things pr, but a I tested at pr that's ready for your review.One of the other intuition pumps we use there is if a human gave you a PR asked you to review it and you hadn't, they hadn't tested it, you'd also be annoyed because you'd be like, only ask me for a review once it's actually ready. So that's what we've done withTesting Defaults and Controlsswyx: simple question I wanted to gather out front.Some prs are way smaller, [00:03:00] like just copy change. Does it always do the video or is it sometimes,Jonas: Sometimes.swyx: Okay. So what's the judgment?Jonas: The model does it? So we we do some default prompting with sort. What types of changes to test? There's a slash command that people can do called slash no test, where if you do that, the model will not test,swyx: but the default is test.Jonas: The default is to be calibrated. So we tell it don't test, very simple copy changes, but test like more complex things. And then users can also write their agents.md and specify like this type of, if you're editing this subpart of my mono repo, never tested ‘cause that won't work or whatever.Videos and Remote ControlJonas: So pillar one is the model actually testing Pillar two is the model coming back with a video of what it did.We have found that in this new world where agents can end-to-end, write much more code, reviewing the code is one of these new bottlenecks that crop up. And so reviewing a video is not a substitute for reviewing code, but it is an entry point that is much, much easier to start with than glancing at [00:04:00] some giant diff.And so typically you kick one off you, it's done you come back and the first thing that you would do is watch this video. So this is a, video of it. In this case I wanted a tool tip over this button. And so it went and showed me what that looks like in, in this video that I think here, it actually used a gallery.So sometimes it will build storybook type galleries where you can see like that component in action. And so that's pillar two is like these demo videos of what it built. And then pillar number three is I have full remote control access to this vm. So I can go heat in here. I can hover things, I can type, I have full control.And same thing for the terminal. I have full access. And so that is also really useful because sometimes the video is like all you need to see. And oftentimes by the way, the video's not perfect, the video will show you, is this worth either merging immediately or oftentimes is this worth iterating with to get it to that final stage where I am ready to merge in.So I can go through some other examples where the first video [00:05:00] wasn't perfect, but it gave me confidence that we were on the right track and two or three follow-ups later, it was good to go. And then I also have full access here where some things you just wanna play around with. You wanna get a feel for what is this and there's no substitute to a live preview.And the VNC kind of VM remote access gives you that.swyx: Amazing What, sorry? What is VN. AndJonas: just the remote desktop. Remote desktop. Yeah.swyx: Sam, any other details that you always wanna call out?Samantha: Yeah, for me the videos have been super helpful. I would say, especially in cases where a common problem for me with agents and cloud agents beforehand was almost like under specification in my requests where our plan mode and going really back and forth and getting detailed implementation spec is a way to reduce the risk of under specification, but then similar to how human communication breaks down over time, I feel like you have this risk where it's okay, when I pull down, go to the triple of pulling down and like running this branch locally, I'm gonna see that, like I said, this should be a toggle and you have a checkbox and like, why didn't you get that detail?And having the video up front just [00:06:00] has that makes that alignment like you're talking about a shared artifact with the agent. Very clear, which has been just super helpful for me.Jonas: I can quickly run through some other Yes. Examples.Meta Agents and More DemosJonas: So this is a very front end heavy one. So one question I wasswyx: gonna say, is this only for frontJonas: end?Exactly. One question you might have is this only for front end? So this is another example where the thing I wanted it to implement was a better error message for saving secrets. So the cloud agents support adding secrets, that's part of what it needs to access certain systems. Part of onboarding that is giving access.This is cloud is working onswyx: cloud agents. Yes.Jonas: So this is a fun thing isSamantha: it can get super meta. ItJonas: can get super meta, it can start its own cloud agents, it can talk to its own cloud agents. Sometimes it's hard to wrap your mind around that. We have disabled, it's cloud agents starting more cloud agents. So we currently disallow that.Someday you might. Someday we might. Someday we might. So this actually was mostly a backend change in terms of the error handling here, where if the [00:07:00] secret is far too large, it would oh, this is actually really cool. Wow. That's the Devrel tools. That's the Devrel tools. So if the secret is far too large, we.Allow secrets above a certain size. We have a size limit on them. And the error message there was really bad. It was just some generic failed to save message. So I was like, Hey, we wanted an error message. So first cool thing it did here, zero prompting on how to test this. Instead of typing out the, like a character 5,000 times to hit the limit, it opens Devrel tools, writes js, or to paste into the input 5,000 characters of the letter A and then hit save, closes the Devrel tools, hit save and gets this new gets the new error message.So that looks like the video actually cut off, but here you can see the, here you can see the screenshot of the of the error message. What, so that is like frontend backend end-to-end feature to, to get that,swyx: yeah.Jonas: Andswyx: And you just need a full vm, full computer run everything.Okay. Yeah.Jonas: Yeah. So we've had versions of this. This is one of the auto tab lessons where we started that in 2022. [00:08:00] No, in 2023. And at the time it was like browser use, DOM, like all these different things. And I think we ended up very sort of a GI pilled in the sense that just give the model pixels, give it a box, a brain in a box is what you want and you want to remove limitations around context and capabilities such that the bottleneck should be the intelligence.And given how smart models are today, that's a very far out bottleneck. And so giving it its full VM and having it be onboarded with Devrel X set up like a human would is just been for us internally a really big step change in capability.swyx: Yeah I would say, let's call it a year ago the models weren't even good enough to do any of this stuff.SoSamantha: even six months ago. Yeah.swyx: So yeah what people have told me is like round about Sonder four fire is when this started being good enough to just automate fully by pixel.Jonas: Yeah, I think it's always a question of when is good enough. I think we found in particular with Opus 4 5, 4, 6, and Codex five three, that those were additional step [00:09:00] changes in the autonomy grade capabilities of the model to just.Go off and figure out the details and come back when it's done.swyx: I wanna appreciate a couple details. One 10 Stack Router. I see it. Yeah. I'm a big fan. Do you know any, I have to name the 10 Stack.Jonas: No.swyx: This just a random lore. Some buddy Sue Tanner. My and then the other thing if you switch back to the video.Jonas: Yeah.swyx: I wanna shout out this thing. Probably Sam did it. I don't knowJonas: the chapters.swyx: What is this called? Yeah, this is called Chapters. Yeah. It's like a Vimeo thing. I don't know. But it's so nice the design details, like the, and obviously a company called Cursor has to have a beautiful cursorSamantha: and it isswyx: the cursor.Samantha: Cursor.swyx: You see it branded? It's the cursor. Cursor, yeah. Okay, cool. And then I was like, I complained to Evan. I was like, okay, but you guys branded everything but the wallpaper. And he was like, no, that's a cursor wallpaper. I was like, what?Samantha: Yeah. Rio picked the wallpaper, I think. Yeah. The video.That's probably Alexi and yeah, a few others on the team with the chapters on the video. Matthew Frederico. There's been a lot of teamwork on this. It's a huge effort.swyx: I just, I like design details.Samantha: Yeah.swyx: And and then when you download it adds like a little cursor. Kind of TikTok clip. [00:10:00] Yes. Yes.So it's to make it really obvious is from Cursor,Jonas: we did the TikTok branding at the end. This was actually in our launch video. Alexi demoed the cloud agent that built that feature. Which was funny because that was an instance where one of the things that's been a consequence of having these videos is we use best of event where you run head to head different models on the same prompt.We use that a lot more because one of the complications with doing that before was you'd run four models and they would come back with some giant diff, like 700 lines of code times four. It's what are you gonna do? You're gonna review all that's horrible. But if you come back with four 22nd videos, yeah, I'll watch four 22nd videos.And then even if none of them is perfect, you can figure out like, which one of those do you want to iterate with, to get it over the line. Yeah. And so that's really been really fun.Bug Repro WorkflowJonas: Here's another example. That's we found really cool, which is we've actually turned since into a slash command as well slash [00:11:00] repro, where for bugs in particular, the model of having full access to the to its own vm, it can first reproduce the bug, make a video of the bug reproducing, fix the bug, make a video of the bug being fixed, like doing the same pattern workflow with obviously the bug not reproducing.And that has been the single category that has gone from like these types of bugs, really hard to reproduce and pick two tons of time locally, even if you try a cloud agent on it. Are you confident it actually fixed it to when this happens? You'll merge it in 90 seconds or something like that.So this is an example where, let me see if this is the broken one or the, okay, this is the fixed one. Okay. So we had a bug on cursor.com/agents where if you would attach images where remove them. Then still submit your prompt. They would actually still get attached to the prompt. Okay. And so here you can see Cursor is using, its full desktop by the way.This is one of the cases where if you just do, browse [00:12:00] use type stuff, you'll have a bad time. ‘cause now it needs to upload files. Like it just uses its native file viewer to do that. And so you can see here it's uploading files. It's going to submit a prompt and then it will go and open up. So this is the meta, this is cursor agent, prompting cursor agent inside its own environment.And so you can see here bug, there's five images attached, whereas when it's submitted, it only had one image.swyx: I see. Yeah. But you gotta enable that if you're gonna use cur agent inside cur.Jonas: Exactly. And so here, this is then the after video where it went, it does the same thing. It attaches images, removes, some of them hit send.And you can see here, once this agent is up, only one of the images is left in the attachments. Yeah.swyx: Beautiful.Jonas: Okay. So easy merge.swyx: So yeah. When does it choose to do this? Because this is an extra step.Jonas: Yes. I think I've not done a great job yet of calibrating the model on when to reproduce these things.Yeah. Sometimes it will do it of its own accord. Yeah. We've been conservative where we try to have it only do it when it's [00:13:00] quite sure because it does add some amount of time to how long it takes it to work on it. But we also have added things like the slash repro command where you can just do, fix this bug slash repro and then it will know that it should first make you a video of it actually finding and making sure it can reproduce the bug.swyx: Yeah. Yeah. One sort of ML topic this ties into is reward hacking, where while you write test that you update only pass. So first write test, it shows me it fails, then make you test pass, which is a classic like red green.Jonas: Yep.swyx: LikeJonas: A-T-D-D-T-D-Dswyx: thing.No, very cool. Was that the last demo? Is thereJonas: Yeah.Anything I missed on the demos or points that you think? I think thatSamantha: covers it well. Yeah.swyx: Cool. Before we stop the screen share, can you gimme like a, just a tour of the slash commands ‘cause I so God ready. Huh, what? What are the good ones?Samantha: Yeah, we wanna increase discoverability around this too.I think that'll be like a future thing we work on. Yeah. But there's definitely a lot of good stuff nowJonas: we have a lot of internal ones that I think will not be that interesting. Here's an internal one that I've made. I don't know if anyone else at Cursor uses this one. Fix bb.Samantha: I've never heard of it.Jonas: Yeah.[00:14:00]Fix Bug Bot. So this is a thing that we want to integrate more tightly on. So you made it forswyx: yourself.Jonas: I made this for myself. It's actually available to everyone in the team, but yeah, no one knows about it. But yeah, there will be Bug bot comments and so Bug Bot has a lot of cool things. We actually just launched Bug Bot Auto Fix, where you can click a button and or change a setting and it will automatically fix its own things, and that works great in a bunch of cases.There are some cases where having the context of the original agent that created the PR is really helpful for fixing the bugs, because it might be like, oh, the bug here is that this, is a regression and actually you meant to do something more like that. And so having the original prompt and all of the context of the agent that worked on it, and so here I could just do, fix or we used to be able to do fixed PB and it would do that.No test is another one that we've had. Slash repro is in here. We mentioned that one.Samantha: One of my favorites is cloud agent diagnosis. This is one that makes heavy use of the Datadog MCP. Okay. And I [00:15:00] think Nick and David on our team wrote, and basically if there is a problem with a cloud agent we'll spin up a bunch of subs.Like a singleswyx: instance.Samantha: Yeah. We'll take the ideas and argument and spin up a bunch of subagents using the Datadog MCP to explore the logs and find like all of the problems that could have happened with that. It takes the debugging time, like from potentially you can do quick stuff quickly with the Datadog ui, but it takes it down to, again, like a single agent call as opposed to trolling through logs yourself.Jonas: You should also talk about the stuff we've done with transcripts.Samantha: Yes. Also so basically we've also done some things internally. There'll be some versions of this as we ship publicly soon, where you can spit up an agent and give it access to another agent's transcript to either basically debug something that happened.So act as an external debugger. I see. Or continue the conversation. Almost like forking it.swyx: A transcript includes all the chain of thought for the 11 minutes here. 45 minutes there.Samantha: Yeah. That way. Exactly. So basically acting as a like secondary agent that debugs the first, so we've started to push more andswyx: they're all the same [00:16:00] code.It is just the different prompts, but the sa the same.Samantha: Yeah. So basically same cloud agent infrastructure and then same harness. And then like when we do things like include, there's some extra infrastructure that goes into piping in like an external transcript if we include it as an attachment.But for things like the cloud agent diagnosis, that's mostly just using the Datadog MCP. ‘Cause we also launched CPS along with along with this cloud agent launch, launch support for cloud agent cps.swyx: Oh, that was drawn out.Jonas: We won't, we'll be doing a bigger marketing moment for it next week, but, and you can now use CPS andswyx: People will listen to it as well.Yeah,Jonas: they'llSamantha: be ahead of the third. They'll be ahead. And I would I actually don't know if the Datadog CP is like publicly available yet. I realize this not sure beta testing it, but it's been one of my favorites to use. Soswyx: I think that one's interesting for Datadog. ‘cause Datadog wants to own that site.Interesting with Bits. I don't know if you've tried bits.Samantha: I haven't tried bits.swyx: Yeah.Jonas: That's their cloud agentswyx: product. Yeah. Yeah. They want to be like we own your logs and give us our, some part of the, [00:17:00] self-healing software that everyone wants. Yeah. But obviously Cursor has a strong opinion on coding agents and you, you like taking away from the which like obviously you're going to do, and not every company's like Cursor, but it's interesting if you're a Datadog, like what do you do here?Do you expose your logs to FDP and let other people do it? Or do you try to own that it because it's extra business for you? Yeah. It's like an interesting one.Samantha: It's a good question. All I know is that I love the Datadog MCP,Jonas: And yeah, it is gonna be no, no surprise that people like will demand it, right?Samantha: Yeah.swyx: It's, it's like anysystemswyx: of record company like this, it's like how much do you give away? Cool. I think that's that for the sort of cloud agents tour. Cool. And we just talk about like cloud agents have been when did Kirsten loves cloud agents? Do you know, in JuneJonas: last year.swyx: June last year. So it's been slowly develop the thing you did, like a bunch of, like Michael did a post where himself, where he like showed this chart of like ages overtaking tap. And I'm like, wow, this is like the biggest transition in code.Jonas: Yeah.swyx: Like in, in [00:18:00] like the last,Jonas: yeah. I think that kind of got turned out.Yeah. I think it's a very interest,swyx: not at all. I think it's been highlighted by our friend Andre Kati today.Jonas: Okay.swyx: Talk more about it. What does it mean? Yeah. Is I just got given like the cursor tab key.Jonas: Yes. Yes.swyx: That's that'sSamantha: cool.swyx: I know, but it's gonna be like put in a museum.Jonas: It is.Samantha: I have to say I haven't used tab a little bit myself.Jonas: Yeah. I think that what it looks like to code with AI code generally creates software, even if you want to go higher level. Is changing very rapidly. No, not a hot take, but I think from our vendor's point at Cursor, I think one of the things that is probably underappreciated from the outside is that we are extremely self-aware about that fact and Kerscher, got its start in phase one, era one of like tab and auto complete.And that was really useful in its time. But a lot of people start looking at text files and editing code, like we call it hand coding. Now when you like type out the actual letters, it'sswyx: oh that's cute.Jonas: Yeah.swyx: Oh that's cute.Jonas: You're so boomer. So boomer. [00:19:00] And so that I think has been a slowly accelerating and now in the last few months, rapidly accelerating shift.And we think that's going to happen again with the next thing where the, I think some of the pains around tab of it's great, but I actually just want to give more to the agent and I don't want to do one tab at a time. I want to just give it a task and it goes off and does a larger unit of work and I can.Lean back a little bit more and operate at that higher level of abstraction that's going to happen again, where it goes from agents handing you back diffs and you're like in the weeds and giving it, 32nd to three minute tasks, to, you're giving it, three minute to 30 minute to three hour tasks and you're getting back videos and trying out previews rather than immediately looking at diffs every single time.swyx: Yeah. Anything to add?Samantha: One other shift that I've noticed as our cloud agents have really taken off internally has been a shift from primarily individually driven development to almost this collaborative nature of development for us, slack is actually almost like a development on [00:20:00] Id basically.So Iswyx: like maybe don't even build a custom ui, like maybe that's like a debugging thing, but actually it's that.Samantha: I feel like, yeah, there's still so much to left to explore there, but basically for us, like Slack is where a lot of development happens. Like we will have these issue channels or just like this product discussion channels where people are always at cursing and that kicks off a cloud agent.And for us at least, we have team follow-ups enabled. So if Jonas kicks off at Cursor in a thread, I can follow up with it and add more context. And so it turns into almost like a discussion service where people can like collaborate on ui. Oftentimes I will kick off an investigation and then sometimes I even ask it to get blame and then tag people who should be brought in. ‘cause it can tag people in Slack and then other people will comeswyx: in, can tag other people who are not involved in conversation. Yes. Can just do at Jonas if say, was talking to,Samantha: yeah.swyx: That's cool. You should, you guys should make a big good deal outta that.Samantha: I know. It's a lot to, I feel like there's a lot more to do with our slack surface area to show people externally. But yeah, basically like it [00:21:00] can bring other people in and then other people can also contribute to that thread and you can end up with a PR again, with the artifacts visible and then people can be like, okay, cool, we can merge this.So for us it's like the ID is almost like moving into Slack in some ways as well.swyx: I have the same experience with, but it's not developers, it's me. Designer salespeople.Samantha: Yeah.swyx: So me on like technical marketing, vision, designer on design and then salespeople on here's the legal source of what we agreed on.And then they all just collaborate and correct. The agents,Jonas: I think that we found when these threads is. The work that is left, that the humans are discussing in these threads is the nugget of what is actually interesting and relevant. It's not the boring details of where does this if statement go?It's do we wanna ship this? Is this the right ux? Is this the right form factor? Yeah. How do we make this more obvious to the user? It's like those really interesting kind of higher order questions that are so easy to collaborate with and leave the implementation to the cloud agent.Samantha: Totally. And no more discussion of am I gonna do this? Are you [00:22:00] gonna do this cursor's doing it? You just have to decide. You like it.swyx: Sometimes the, I don't know if there's a, this probably, you guys probably figured this out already, but since I, you need like a mute button. So like cursor, like we're going to take this offline, but still online.But like we need to talk among the humans first. Before you like could stop responding to everything.Jonas: Yeah. This is a design decision where currently cursor won't chime in unless you explicitly add Mention it. Yeah. Yeah.Samantha: So it's not always listening.Yeah.Jonas: I can see all the intermediate messages.swyx: Have you done the recursive, can cursor add another cursor or spawn another cursor?Samantha: Oh,Jonas: we've done some versions of this.swyx: Because, ‘cause it can add humans.Jonas: Yes. One of the other things we've been working on that's like an implication of generating the code is so easy is getting it to production is still harder than it should be.And broadly, you solve one bottleneck and three new ones pop up. Yeah. And so one of the new bottlenecks is getting into production and we have a like joke internally where you'll be talking about some feature and someone says, I have a PR for that. Which is it's so easy [00:23:00] to get to, I a PR for that, but it's hard still relatively to get from I a PR for that to, I'm confident and ready to merge this.And so I think that over the coming weeks and months, that's a thing that we think a lot about is how do we scale up compute to that pipeline of getting things from a first draft An agent did.swyx: Isn't that what Merge isn't know what graphite's for, likeJonas: graphite is a big part of that. The cloud agent testingswyx: Is it fully integrated or still different companiesJonas: working on I think we'll have more to share there in the future, but the goal is to have great end-to-end experience where Cursor doesn't just help you generate code tokens, it helps you create software end-to-end.And so review is a big part of that, that I think especially as models have gotten much better at writing code, generating code, we've felt that relatively crop up more,swyx: sorry this is completely unplanned, but like there I have people arguing one to you need ai. To review ai and then there is another approach, thought school of thought where it's no, [00:24:00] reviews are dead.Like just show me the video. It's it like,Samantha: yeah. I feel again, for me, the video is often like alignment and then I often still wanna go through a code review process.swyx: Like still look at the files andSamantha: everything. Yeah. There's a spectrum of course. Like the video, if it's really well done and it does like fully like test everything, you can feel pretty competent, but it's still helpful to, to look at the code.I make hep pay a lot of attention to bug bot. I feel like Bug Bot has been a great really highly adopted internally. We often like, won't we tell people like, don't leave bug bot comments unaddressed. ‘cause we have such high confidence in it. So people always address their bug bot comments.Jonas: Once you've had two cases where you merged something and then you went back later, there was a bug in it, you merged, you went back later and you were like, ah, bug Bot had found that I should have listened to Bug Bot.Once that happens two or three times, you learn to wait for bug bot.Samantha: Yeah. So I think for us there's like that code level review where like it's looking at the actual code and then there's like the like feature level review where you're looking at the features. There's like a whole number of different like areas.There'll probably eventually be things like performance level review, security [00:25:00] review, things like that where it's like more more different aspects of how this feature might affect your code base that you want to potentially leverage an agent to help with.Jonas: And some of those like bug bot will be synchronous and you'll typically want to wait on before you merge.But I think another thing that we're starting to see is. As with cloud agents, you scale up this parallelism and how much code you generate. 10 person startups become, need the Devrel X and pipelines that a 10,000 person company used to need. And that looks like a lot of the things I think that 10,000 person companies invented in order to get that volume of software to production safely.So that's things like, release frequently or release slowly, have different stages where you release, have checkpoints, automated ways of detecting regressions. And so I think we're gonna need stacks merg stack diffs merge queues. Exactly. A lot of those things are going to be importantswyx: forward with.I think the majority of people still don't know what stack stacks are. And I like, I have many friends in Facebook and like I, I'm pretty friendly with graphite. I've just, [00:26:00] I've never needed it ‘cause I don't work on that larger team and it's just like democratization of no, only here's what we've already worked out at very large scale and here's how you can, it benefits you too.Like I think to me, one of the beautiful things about GitHub is that. It's actually useful to me as an individual solo developer, even though it's like actually collaboration software.Jonas: Yep.swyx: And I don't think a lot of Devrel tools have figured that out yet. That transition from like large down to small.Jonas: Yeah. Kers is probably an inverse story.swyx: This is small down toJonas: Yeah. Where historically Kers share, part of why we grew so quickly was anyone on the team could pick it up and in fact people would pick it up, on the weekend for their side project and then bring it into work. ‘cause they loved using it so much.swyx: Yeah.Jonas: And I think a thing that we've started working on a lot more, not us specifically, but as a company and other folks at Cursor, is making it really great for teams and making it the, the 10th person that starts using Cursor in a team. Is immediately set up with things like, we launched Marketplace recently so other people can [00:27:00] configure what CPS and skills like plugins.So skills and cps, other people can configure that. So that my cursor is ready to go and set up. Sam loves the Datadog, MCP and Slack, MCP you've also been using a lot butSamantha: also pre-launch, but I feel like it's so good.Jonas: Yeah, my cursor should be configured if Sam feels strongly that's just amazing and required.swyx: Is it automatically shared or you have to go and.Jonas: It depends on the MCP. So some are obviously off per user. Yeah. And so Sam can't off my cursor with my Slack MCP, but some are team off and those can be set up by admins.swyx: Yeah. Yeah. That's cool. Yeah, I think, we had a man on the pod when cursor was five people, and like everyone was like, okay, what's the thing?And then it's usually something teams and org and enterprise, but it's actually working. But like usually at that stage when you're five, when you're just a vs. Code fork it's like how do you get there? Yeah. Will people pay for this? People do pay for it.Jonas: Yeah. And I think for cloud agents, we expect.[00:28:00]To have similar kind of PLG things where I think off the bat we've seen a lot of adoption with kind of smaller teams where the code bases are not quite as complex to set up. Yes. If you need some insane docker layer caching thing for builds not to take two hours, that's going to take a little bit longer for us to be able to support that kind of infrastructure.Whereas if you have front end backend, like one click agents can install everything that they need themselves.swyx: This is a good chance for me to just ask some technical sort of check the box questions. Can I choose the size of the vm?Jonas: Not yet. We are planning on adding that. Weswyx: have, this is obviously you want like LXXL, whatever, right?Like it's like the Amazon like sort menu.Jonas: Yes, exactly. We'll add that.swyx: Yeah. In some ways you have to basically become like a EC2, almost like you rent a box.Jonas: You rent a box. Yes. We talk a lot about brain in a box. Yeah. So cursor, we want to be a brain in a box,swyx: but is the mental model different? Is it more serverless?Is it more persistent? Is. Something else.Samantha: We want it to be a bit persistent. The desktop should be [00:29:00] something you can return to af even after some days. Like maybe you go back, they're like still thinking about a feature for some period of time. So theswyx: full like sus like suspend the memory and bring it back and then keep going.Samantha: Exactly.swyx: That's an interesting one because what I actually do want, like from a manna and open crawl, whatever, is like I want to be able to log in with my credentials to the thing, but not actually store it in any like secret store, whatever. ‘cause it's like this is the, my most sensitive stuff.Yeah. This is like my email, whatever. And just have it like, persist to the image. I don't know how it was hood, but like to rehydrate and then just keep going from there. But I don't think a lot of infra works that way. A lot of it's stateless where like you save it to a docker image and then it's only whatever you can describe in a Docker file and that's it.That's the only thing you can cl multiple times in parallel.Jonas: Yeah. We have a bunch of different ways of setting them up. So there's a dockerfile based approach. The main default way is actually snapshottingswyx: like a Linux vmJonas: like vm, right? You run a bunch of install commands and then you snapshot more or less the file system.And so that gets you set up for everything [00:30:00] that you would want to bring a new VM up from that template basically.swyx: Yeah.Jonas: And that's a bit distinct from what Sam was talking about with the hibernating and re rehydrating where that is a full memory snapshot as well. So there, if I had like the browser open to a specific page and we bring that back, that page will still be there.swyx: Was there any discussion internally and just building this stuff about every time you shoot a video it's actually you show a little bit of the desktop and the browser and it's not necessary if you just show the browser. If, if you know you're just demoing a front end application.Why not just show the browser, right? Like it Yeah,Samantha: we do have some panning and zooming. Yeah. Like it can decide that when it's actually recording and cutting the video to highlight different things. I think we've played around with different ways of segmenting it and yeah. There's been some different revs on it for sure.Jonas: Yeah. I think one of the interesting things is the version that you see now in cursor.com actually is like half of what we had at peak where we decided to unshift or unshipped quite a few things. So two of the interesting things to talk about, one is directly an answer to your [00:31:00] question where we had native browser that you would have locally, it was basically an iframe that via port forwarding could load the URL could talk to local host in the vm.So that gets you basically, so inswyx: your machine's browser,likeJonas: in your local browser? Yeah. You would go to local host 4,000 and that would get forwarded to local host 4,000 in the VM via port forward. We unshift that like atswyx: Eng Rock.Jonas: Like an Eng Rock. Exactly. We unshift that because we felt that the remote desktop was sufficiently low latency and more general purpose.So we build Cursor web, but we also build Cursor desktop. And so it's really useful to be able to have the full spectrum of things. And even for Cursor Web, as you saw in one of the examples, the agent was uploading files and like I couldn't upload files and open the file viewer if I only had access to the browser.And we've thought a lot about, this might seem funny coming from Cursor where we started as this, vs. Code Fork and I think inherited a lot of amazing things, but also a lot [00:32:00] of legacy UI from VS Code.Minimal Web UI SurfacesJonas: And so with the web UI we wanted to be very intentional about keeping that very minimal and exposing the right sum of set of primitive sort of app surfaces we call them, that are shared features of that cloud.Environment that you and the agent both use. So agent uses desktop and controls it. I can use desktop and controlled agent runs terminal commands. I can run terminal commands. So that's how our philosophy around it. The other thing that is maybe interesting to talk about that we unshipped is and we may, both of these things we may reship and decide at some point in the future that we've changed our minds on the trade offs or gotten it to a point where, putswyx: it out there.Let users tell you they want it. Exactly. Alright, fine.Why No File EditorJonas: So one of the other things is actually a files app. And so we used to have the ability at one point during the process of testing this internally to see next to, I had GID desktop and terminal on the right hand side of the tab there earlier to also have a files app where you could see and edit files.And we actually felt that in some [00:33:00] ways, by restricting and limiting what you could do there, people would naturally leave more to the agent and fall into this new pattern of delegating, which we thought was really valuable. And there's currently no way in Cursor web to edit these files.swyx: Yeah. Except you like open up the PR and go into GitHub and do the thing.Jonas: Yeah.swyx: Which is annoying.Jonas: Just tell the agent,swyx: I have criticized open AI for this. Because Open AI is Codex app doesn't have a file editor, like it has file viewer, but isn't a file editor.Jonas: Do you use the file viewer a lot?swyx: No. I understand, but like sometimes I want it, the one way to do it is like freaking going to no, they have a open in cursor button or open an antigravity or, opening whatever and people pointed that.So I was, I was part of the early testers group people pointed that and they were like, this is like a design smell. It's like you actually want a VS. Code fork that has all these things, but also a file editor. And they were like, no, just trust us.Jonas: Yeah. I think we as Cursor will want to, as a product, offer the [00:34:00] whole spectrum and so you want to be able to.Work at really high levels of abstraction and double click and see the lowest level. That's important. But I also think that like you won't be doing that in Slack. And so there are surfaces and ways of interacting where in some cases limiting the UX capabilities makes for a cleaner experience that's more simple and drives people into these new patterns where even locally we kicked off joking about this.People like don't really edit files, hand code anymore. And so we want to build for where that's going and not where it's beenswyx: a lot of cool stuff. And Okay. I have a couple more.Full Stack Hosting Debateswyx: So observations about the design elements about these things. One of the things that I'm always thinking about is cursor and other peers of cursor start from like the Devrel tools and work their way towards cloud agents.Other people, like the lovable and bolts of the world start with here's like the vibe code. Full cloud thing. They were already cloud edges before anyone else cloud edges and we will give you the full deploy platform. So we own the whole loop. We own all the infrastructure, we own, we, we have the logs, we have the the live site, [00:35:00] whatever.And you can do that cycle cursor doesn't own that cycle even today. You don't have the versal, you don't have the, you whatever deploy infrastructure that, that you're gonna have, which gives you powers because anyone can use it. And any enterprise who, whatever you infra, I don't care. But then also gives you limitations as to how much you can actually fully debug end to end.I guess I'm just putting out there that like is there a future where there's like full stack cursor where like cursor apps.com where like I host my cursor site this, which is basically a verse clone, right? I don't know.Jonas: I think that's a interesting question to be asking, and I think like the logic that you laid out for how you would get there is logic that I largely agree with.swyx: Yeah. Yeah.Jonas: I think right now we're really focused on what we see as the next big bottleneck and because things like the Datadog MCP exist, yeah. I don't think that the best way we can help our customers ship more software. Is by building a hosting solution right now,swyx: by the way, these are things I've actually discussed with some of the companies I just named.Jonas: Yeah, for sure. Right now, just this big bottleneck is getting the code out there and also [00:36:00] unlike a lovable in the bolt, we focus much more on existing software. And the zero to one greenfield is just a very different problem. Imagine going to a Shopify and convincing them to deploy on your deployment solution.That's very different and I think will take much longer to see how that works. May never happen relative to, oh, it's like a zero to one app.swyx: I'll say. It's tempting because look like 50% of your apps are versal, superb base tailwind react it's the stack. It's what everyone does.So I it's kinda interesting.Jonas: Yeah.Model Choice and Auto Routingswyx: The other thing is the model select dying. Right now in cloud agents, it's stuck down, bottom left. Sure it's Codex High today, but do I care if it's suddenly switched to Opus? Probably not.Samantha: We definitely wanna give people a choice across models because I feel like it, the meta change is very frequently.I was a big like Opus 4.5 Maximalist, and when codex 5.3 came out, I hard, hard switch. So that's all I use now.swyx: Yeah. Agreed. I don't know if, but basically like when I use it in Slack, [00:37:00] right? Cursor does a very good job of exposing yeah. Cursors. If people go use it, here's the model we're using.Yeah. Here's how you switch if you want. But otherwise it's like extracted away, which is like beautiful because then you actually, you should decide.Jonas: Yeah, I think we want to be doing more with defaults.swyx: Yeah.Jonas: Where we can suggest things to people. A thing that we have in the editor, the desktop app is auto, which will route your request and do things there.So I think we will want to do something like that for cloud agents as well. We haven't done it yet. And so I think. We have both people like Sam, who are very savvy and want know exactly what model they want, and we also have people that want us to pick the best model for them because we have amazing people like Sam and we, we are the experts.Yeah. We have both the traffic and the internal taste and experience to know what we think is best.swyx: Yeah. I have this ongoing pieces of agent lab versus model lab. And to me, cursor and other companies are example of an agent lab that is, building a new playbook that is different from a model lab where it's like very GP heavy Olo.So obviously has a research [00:38:00] team. And my thesis is like you just, every agent lab is going to have a router because you're going to be asked like, what's what. I don't keep up to every day. I'm not a Sam, I don't keep up every day for using you as sample the arm arbitrator of taste. Put me on CRI Auto.Is it free? It's not free.Jonas: Auto's not free, but there's different pricing tiers. Yeah.swyx: Put me on Chris. You decide from me based on all the other people you know better than me. And I think every agent lab should basically end up doing this because that actually gives you extra power because you like people stop carrying or having loyalty with one lab.Jonas: Yeah.Best Of N and Model CouncilsJonas: Two other maybe interesting things that I don't know how much they're on your radar are one the best event thing we mentioned where running different models head to head is actually quite interesting becauseswyx: which exists in cursor.Jonas: That exists in cur ID and web. So the problem is where do you run them?swyx: Okay.Jonas: And so I, I can share my screen if that's interesting. Yeahinteresting.swyx: Yeah. Yeah. Obviously parallel agents, very popal.Jonas: Yes, exactly. Parallel agentsswyx: in you mind. Are they the same thing? Best event and parallel agents? I don't want to [00:39:00] put words in your mouth.Jonas: Best event is a subset of parallel agents where they're running on the same prompt.That would be my answer. So this is what that looks like. And so here in this dropdown picker, I can just select multiple models.swyx: Yeah.Jonas: And now if I do a prompt, I'm going to do something silly. I am running these five models.swyx: Okay. This is this fake clone, of course. The 2.0 yeah.Jonas: Yes, exactly. But they're running so the cursor 2.0, you can do desktop or cloud.So this is cloud specifically where the benefit over work trees is that they have their own VMs and can run commands and won't try to kill ports that the other one is running. Which are some of the pains. These are allswyx: called work trees?Jonas: No, these are all cloud agents with their own VMs.swyx: Okay. ButJonas: When you do it locally, sometimes people do work trees and that's been the main way that people have set out parallel so far.I've gotta say.swyx: That's so confusing for folks.Jonas: Yeah.swyx: No one knows what work trees are.Jonas: Exactly. I think we're phasing out work trees.swyx: Really.Jonas: Yeah.swyx: Okay.Samantha: But yeah. And one other thing I would say though on the multimodel choice, [00:40:00] so this is another experiment that we ran last year and the decide to ship at that time but may come back to, and there was an interesting learning that's relevant for, these different model providers. It was something that would run a bunch of best of ends but then synthesize and basically run like a synthesizer layer of models. And that was other agents that would take LM Judge, but one that was also agentic and could write code. So it wasn't just picking but also taking the learnings from two models or, and models that it was looking at and writing a new diff.And what we found was that at the time at least, there were strengths to using models from different model providers as the base level of this process. Like basically you could get almost like a synergistic output that was better than having a very unified, like bottom model tier. So it was really interesting ‘cause it's like potentially, even though even in the future when you have like maybe one model as ahead of the other for a little bit, there could be some benefit from having like multiple top tier models involved in like a [00:41:00] model swarm or whatever agent Swarm that you're doing, that they each have strengths and weaknesses.Yeah.Jonas: Andre called this the council, right?Samantha: Yeah, exactly. We actually, oh, that's another internal command we have that Ian wrote slash council. Oh, and they some, yeah.swyx: Yes. This idea is in various forms everywhere. And I think for me, like for me, the productization of it, you guys have done yeah, like this is very flexible, but.If I were to add another Yeah, what your thing is on here it would be too much. I what, let's say,Samantha: Ideally it's all, it's something that the user can just choose and it all happens under the hood in a way where like you just get the benefit of that process at the end and better output basically, but don't have to get too lost in the complexity of judging along the way.Jonas: Okay.Subagents for ContextJonas: Another thing on the many agents, on different parallel agents that's interesting is an idea that's been around for a while as well that has started working recently is subagents. And so this is one other way to get agents of the different prompts and different goals and different models, [00:42:00] different vintages to work together.Collaborate and delegate.swyx: Yeah. I'm very like I like one of my, I always looking for this is the year of the blah, right? Yeah. I think one of the things on the blahs is subs. I think this is of but I haven't used them in cursor. Are they fully formed or how do I honestly like an intro because do I form them from new every time?Do I have fixed subagents? How are they different for slash commands? There's all these like really basic questions that no one stops to answer for people because everyone's just like too busy launching. We have toSamantha: honestly, you could, you can see them in cursor now if you just say spin up like 50 subagents to, so cursor definesswyx: what Subagents.Yeah.Samantha: Yeah. So basically I think I shouldn't speak for the whole subagents team. This is like a different team that's been working on this, but our thesis or thing that we saw internally is that like they're great for context management for kind of long running threads, or if you're trying to just throw more compute at something.We have strongly used, almost like a generic task interface where then the main agent can define [00:43:00] like what goes into the subagent. So if I say explore my code base, it might decide to spin up an explore subagent and or might decide to spin up five explore subagent.swyx: But I don't get to set what those subagent are, right?It's all defined by a model.Samantha: I think. I actually would have to refresh myself on the sub agent interface.Jonas: There are some built-in ones like the explore subagent is free pre-built. But you can also instruct the model to use other subagents and then it will. And one other example of a built-in subagent is I actually just kicked one off in cursor and I can show you what that looks like.swyx: Yes. Because I tried to do this in pure prompt space.Jonas: So this is the desktop app? Yeah. Yeah. And that'sswyx: all you need to do, right? Yeah.Jonas: That's all you need to do. So I said use a sub agent to explore and I think, yeah, so I can even click in and see what the subagent is working on here. It ran some fine command and this is a composer under the hood.Even though my main model is Opus, it does smart routing to take, like in this instance the explorer sort of requires reading a ton of things. And so a faster model is really useful to get an [00:44:00] answer quickly, but that this is what subagent look like. And I think we wanted to do a lot more to expose hooks and ways for people to configure these.Another example of a cus sort of builtin subagent is the computer use subagent in the cloud agents, where we found that those trajectories can be long and involve a lot of images obviously, and execution of some testing verification task. We wanted to use that models that are particularly good at that.So that's one reason to use subagents. And then the other reason to use subagents is we want contexts to be summarized reduced down at a subagent level. That's a really neat boundary at which to compress that rollout and testing into a final message that agent writes that then gets passed into the parent rather than having to do some global compaction or something like that.swyx: Awesome. Cool. While we're in the subagents conversation, I can't do a cursor conversation and not talk about listen stuff. What is that? What is what? He built a browser. He built an os. Yes. And he [00:45:00] experimented with a lot of different architectures and basically ended up reinventing the software engineer org chart.This is all cool, but what's your take? What's, is there any hole behind the side? The scenes stories about that kind of, that whole adventure.Samantha: Some of those experiments have found their way into a feature that's available in cloud agents now, the long running agent mode internally, we call it grind mode.And I think there's like some hint of grind mode accessible in the picker today. ‘cause you can do choose grind until done. And so that was really the result of experiments that Wilson started in this vein where he I think the Ralph Wigga loop was like floating around at the time, but it was something he also independently found and he was experimenting with.And that was what led to this product surface.swyx: And it is just simple idea of have criteria for completion and do not. Until you complete,Samantha: there's a bit more complexity as well in, in our implementation. Like there's a specific, you have to start out by aligning and there's like a planning stage where it will work with you and it will not get like start grind execution mode until it's decided that the [00:46:00] plan is amenable to both of you.Basically,swyx: I refuse to work until you make me happy.Jonas: We found that it's really important where people would give like very underspecified prompt and then expect it to come back with magic. And if it's gonna go off and work for three minutes, that's one thing. When it's gonna go off and work for three days, probably should spend like a few hours upfront making sure that you have communicated what you actually want.swyx: Yeah. And just to like really drive from the point. We really mean three days that No, noJonas: human. Oh yeah. We've had three day months innovation whatsoever.Samantha: I don't know what the record is, but there's been a long time with the grantsJonas: and so the thing that is available in cursor. The long running agent is if you wanna think about it, very abstractly that is like one worker node.Whereas what built the browser is a society of workers and planners and different agents collaborating. Because we started building the browser with one worker node at the time, that was just the agent. And it became one worker node when we realized that the throughput of the system was not where it needed to be [00:47:00] to get something as large of a scale as the browser done.swyx: Yeah.Jonas: And so this has also become a really big mental model for us with cloud, cloud agents is there's the classic engineering latency throughput trade-offs. And so you know, the code is water flowing through a pipe. The, we think that over the coming months, the big unlock is not going to be one person with a model getting more done, like the water flowing faster and we'll be making the pipe much wider and so ing more, whether that's swarms of agents or parallel agents, both of those are things that contribute to getting.Much more done in the same amount of time, but any one of those tasks doesn't necessarily need to get done that quickly. And throughput is this really big thing where if you see the system of a hundred concurrent agents outputting thousands of tokens a second, you can't go back like that.Just you see a glimpse of the future where obviously there are many caveats. Like no one is using this browser. IRL. There's like a bunch of things not quite right yet, but we are going to get to systems that produce real production [00:48:00] code at the scale much sooner than people think. And it forces you to think what even happens to production systems. Like we've broken our GitHub actions recently because we have so many agents like producing and pushing code that like CICD is just overloaded. ‘cause suddenly it's like effectively weg grew, cursor's growing very quickly anyway, but you grow head count, 10 x when people run 10 x as many agents.And so a lot of these systems, exactly, a lot of these systems will need to adapt.swyx: It also reminds me, we, we all, the three of us live in the app layer, but if you talk to the researchers who are doing RL infrastructure, it's the same thing. It's like all these parallel rollouts and scheduling them and making sure as much throughput as possible goes through them.Yeah, it's the same thing.Jonas: We were talking briefly before we started recording. You were mentioning memory chips and some of the shortages there. The other thing that I think is just like hard to wrap your head around the scale of the system that was building the browser, the concurrency there.If Sam and I both have a system like that running for us, [00:49:00] shipping our software. The amount of inference that we're going to need per developer is just really mind-boggling. And that makes, sometimes when I think about that, I think that even with, the most optimistic projections for what we're going to need in terms of buildout, our underestimating, the extent to which these swarm systems can like churn at scale to produce code that is valuable to the economy.And,swyx: yeah, you can cut this if it's sensitive, but I was just Do you have estimates of how much your token consumption is?Jonas: Like per developer?swyx: Yeah. Or yourself. I don't need like comfy average. I just curious. ISamantha: feel like I, for a while I wasn't an admin on the usage dashboard, so I like wasn't able to actually see, but it was a,swyx: mine has gone up.Samantha: Oh yeah.swyx: But I thinkSamantha: it's in terms of how much work I'm doing, it's more like I have no worries about developers losing their jobs, at least in the near term. ‘cause I feel like that's a more broad discussion.swyx: Yeah. Yeah. You went there. I didn't go, I wasn't going there.I was just like how much more are you using?Samantha: There's so much stuff to be built. And so I feel like I'm basically just [00:50:00] trying to constantly I have more ambitions than I did before. Yes. Personally. Yes. So can't speak to the broader thing. But for me it's like I'm busier than ever before.I'm using more tokens and I am also doing more things.Jonas: Yeah. Yeah. I don't have the stats for myself, but I think broadly a thing that we've seen, that we expect to continue is J'S paradox. Whereswyx: you can't do it in our podcast without seeingJonas: it. Exactly. We've done it. Now we can wrap. We've done, we said the words.Phase one tab auto complete people paid like 20 bucks a month. And that was great. Phase two where you were iterating with these local models. Today people pay like hundreds of dollars a month. I think as we think about these highly parallel kind of agents running off for a long times in their own VM system, we are already at that point where people will be spending thousands of dollars a month per human, and I think potentially tens of thousands and beyond, where it's not like we are greedy for like capturing more money, but what happens is just individuals get that much more leverage.And if one person can do as much as 10 people, yeah. That tool that allows ‘em to do that is going to be tremendously valuable [00:51:00] and worth investing in and taking the best thing that exists.swyx: One more question on just the cursor in general and then open-ended for you guys to plug whatever you wanna put.How is Cursor hiring these days?Samantha: What do you mean by how?swyx: So obviously lead code is dead. Oh,Samantha: okay.swyx: Everyone says work trial. Different people have different levels of adoption of agents. Some people can really adopt can be much more productive. But other people, you just need to give them a little bit of time.And sometimes they've never lived in a token rich place like cursor.And once you live in a token rich place, you're you just work differently. But you need to have done that. And a lot of people anyway, it was just open-ended. Like how has agentic engineering, agentic coding changed your opinions on hiring?Is there any like broad like insights? Yeah.Jonas: Basically I'm asking this for other people, right? Yeah, totally. Totally. To hear Sam's opinion, we haven't talked about this the two of us. I think that we don't see necessarily being great at the latest thing with AI coding as a prerequisite.I do think that's a sign that people are keeping up and [00:52:00] curious and willing to upscale themselves in what's happening because. As we were talking about the last three months, the game has completely changed. It's like what I do all day is very different.swyx: Like it's my job and I can't,Jonas: Yeah, totally.I do think that still as Sam was saying, the fundamentals remain important in the current age and being able to go and double click down. And models today do still have weaknesses where if you let them run for too long without cleaning up and refactoring, the coke will get sloppy and there'll be bad abstractions.And so you still do need humans that like have built systems before, no good patterns when they see them and know where to steer things.Samantha: I would agree with that. I would say again, cursor also operates very quickly and leveraging ag agentic engineering is probably one reason why that's possible in this current moment.I think in the past it was just like people coding quickly and now there's like people who use agents to move faster as well. So it's part of our process will always look for we'll select for kind of that ability to make good decisions quickly and move well in this environment.And so I think being able to [00:53:00] figure out how to use agents to help you do that is an important part of it too.swyx: Yeah. Okay. The fork in the road, either predictions for the end of the year, if you have any, or PUDs.Jonas: Evictions are not going to go well.Samantha: I know it's hard.swyx: They're so hard. Get it wrong.It's okay. Just, yeah.Jonas: One other plug that may be interesting that I feel like we touched on but haven't talked a ton about is a thing that the kind of these new interfaces and this parallelism enables is the ability to hop back and forth between threads really quickly. And so a thing that we have,swyx: you wanna show something or,Jonas: yeah, I can show something.A thing that we have felt with local agents is this pain around contact switching. And you have one agent that went off and did some work and another agent that, that did something else. And so here by having, I just have three tabs open, let's say, but I can very quickly, hop in here.This is an example I showed earlier, but the actual workflow here I think is really different in a way that may not be obvious, where, I start t

    Faculty Factory
    Navigating the Post-Career Phase of Faculty Life with Oscar W. “Skip” Brown, MD

    Faculty Factory

    Play Episode Listen Later Mar 6, 2026 27:43


    Despite all the opportunities it opens, retirement can be a hard road if you fail to engage in proper planning, as we explore in this week's episode of the Faculty Factory Podcast with returning guest Skip Brown, MD. As a clinical professor of pediatrics at UTMB in Galveston, Texas, Dr. Brown is a past vice chair for clinical affairs and a former chief medical officer at UTMB. A past president of the Texas Pediatric Society (TPS), he is a recipient of the TPS Charles W. Daeschner, Jr. Lifetime Achievement Award for his contributions to the health and welfare of Texas children. You can check out his first episode with us, “The Definitive Guide to a Fulfilling Retirement Journey,” here: https://facultyfactory.podbean.com/e/the-definitive-guide-to-a-fulfilling-retirement-journey-with-ow-skip-brown-md/ When you retire and reflect on how you want to spend your time, be mindful of the 90/10 rule: 90 percent of the work gets done by 10 percent of the people. “You can become much busier than you might want to be if you donate your time and skills,” he said. Dr. Brown's advice: guard your freedom, stay selective about your time, and resist the pull to take on everything just because you're capable. Equally important is learning to dial back perfectionism. Perhaps the most powerful theme of the conversation was identity. He reflected on colleagues who stayed in their roles not because they wanted to, but because they had no idea who they were outside of their work. The antidote isn't a rigid plan, but genuine reflection. As Dr. Brown put it simply: you're about to work for the most insightful boss you've ever had — yourself. It's worth getting to know them.

    CruxCasts
    Abcourt Mines (TSXV:ABI) - Scaling to 50Kozpa | Profitable Gold Mine with Mill Throughput Upside

    CruxCasts

    Play Episode Listen Later Mar 6, 2026 20:50


    Interview with Pascal Hamelin, President & CEO of Abcourt Mines Inc.Our previous interview: https://www.cruxinvestor.com/posts/abcourt-mines-tsxvabi-cash-flow-in-sight-with-sleeping-giant-ramp-flordin-drills-8693Recording date: 4th March 2026Abcourt Mines (TSXV:ABI) is one of the few junior mining companies to have made the full transition from developer to profitable gold producer in the current cycle. Operating the 100%-owned Sleeping Giant mine and mill in Quebec's Abitibi region, the company recorded its first gold sales in September 2025 and delivered 837 ounces in Q4 2025 which enough to generate a profit from operations. That alone sets Abcourt apart from the majority of junior miners at a comparable stage.The investment case is centred on a single, clearly quantifiable opportunity: the Sleeping Giant mill is running at less than 20% of its nameplate capacity of 800 tonnes per day. The infrastructure is built, commissioned, and performing at over 96% gold recovery. The constraint is not technology or capital, it is underground mining capacity, which is a workforce and development challenge the company is actively and systematically addressing.CEO Pascal Hamelin has set a near-term target of 10,000 tonnes per month by autumn 2026, representing approximately 2,500 ounces monthly and the threshold for strong free cash flow generation. Phase 1 of the production plan targets 30,000 ounces per year by late 2026 or early 2027. The ultimate vision is 800 tonnes per day and 50,000 ounces per year — achievable without any major new capital expenditure, given the mill is already sized for that output.To unlock that capacity, Abcourt is building an on-site sleep camp to resolve a longstanding workforce retention problem caused by long commutes in northern Quebec winters. Phase 2 of the camp (36 rooms) arrives by end of March 2026 and Phase 3 (37 rooms) is due by June 2026. Alongside this, a formal training programme with Val-d'Or's mining school is bringing new miners into the operation on a weekly basis. These are not peripheral initiatives — they are the direct operational enablers of the throughput ramp.The financial structure is also worth noting. Glencore refinanced Abcourt's start-up debt from 16% to 7%, providing a $30 million facility with interest-only payments in year one and principal repayments beginning February 2027. Glencore also holds the offtake on gold and silver production and a right of first participation in future financings. For a junior producer, this level of institutional backing is unusual and meaningful.Management credibility is underscored by insider ownership of approximately 37% — built through years of equity participation alongside external shareholders, not through compensation schemes. Officers and directors have genuine skin in the game.Beyond Sleeping Giant, the company holds 14 additional projects including a zinc-silver polymetallic asset at Abcourt-Barvue, a 5 g/t gold resource at Discovery, and multiple tailings assets being assessed for critical mineral content. These are not currently priced into the market's valuation of the company.For investors evaluating junior gold producers, Abcourt offers a rare combination: proven profitability, a clear and executable growth pathway, institutional validation, and a portfolio of assets that provide upside optionality without requiring additional capital deployment in the near term.View Abcourt Mines' company profile: https://www.cruxinvestor.com/companies/abcourt-mines-incSign up for Crux Investor: https://cruxinvestor.com

    CruxCasts
    ValOre Metals (TSXV:VO) - PGE Developer With Novel Process, Exclusive IP, Clear Path to PEA

    CruxCasts

    Play Episode Listen Later Mar 6, 2026 23:25


    Interview with Nick Smart, Director & CEO of ValOre MetalsOur previous interview: https://www.cruxinvestor.com/posts/valore-metals-tsxvvo-platinum-palladium-project-advances-to-economic-study-9203Recording date: 4th March 2026ValOre Metals is at a defining moment in its evolution from exploration company to project developer. The company's flagship asset, the Pedra Branca PGE project in Ceará state, Brazil, hosts a 2.2 million ounce inferred resource at 1.08 grams per tonne, a resource of genuine scale in a metal category that faces structural supply constraints and growing strategic demand. For the first time, ValOre is now putting the economic framework around that resource through a comprehensive PEA programme targeted for publication by year-end 2025.The project's most distinctive feature is its development approach to the shallow, weathered upper ore body. Rather than applying conventional flotation which performs poorly on oxidised material, ValOre is developing a bioleaching process in partnership with the University of Cape Town's Department of Chemical Engineering. This technique, in which microorganisms are used to extract metals from ore, is industrially proven in copper and increasingly used in refractory gold, but has not previously been applied to a PGE deposit. Phase 1 lab-scale trials have delivered metal recoveries consistently in the high 70s percentage range, and the company has secured exclusive global rights to the jointly developed intellectual property.The implications are significant. The weathered zone accounts for roughly one-third of the total resource ounce count and sits at surface, meaning it can be mined simply and cheaply. A low-cost processing route applied to near-surface material creates the possibility of a viable early-stage operation that generates revenue and validates the process without requiring the capital commitment of a full-scale mine build. Under Brazilian mining law, a trial mining permit enables exactly this kind of phased approach, allowing the company to construct a demonstration plant targeting 10,000 to 15,000 ounces of platinum and palladium per year as a precursor to industrial-scale production of 150,000 to 200,000 ounces annually.The PEA, with a budget of approximately $4 million, is the bridge between the current exploration narrative and an investment-grade development story. It will address mining method, processing economics, capital and operating costs, and route to market for both the weathered and fresh sulphide ore bodies. Engineering consultancy Lycopodium is leading the technical work. Until the PEA is published, investors have lacked a valuation framework for Pedra Branca. Publication changes that and represents a credible re-rating catalyst.Management has taken additional steps to sharpen the investment case. The divestiture of legacy Hatchet uranium properties to Future Fuels removes a non-core distraction and concentrates the company entirely on PGE development. CEO Nick Smart brings direct in-country experience, having spent approximately six years building the Barro Alto nickel mine in Brazil for Anglo American. Brazil itself is actively positioning as a destination for critical minerals investment, with strong government and industry representation at PDAC 2026 underscoring the macro tailwind.The near-term catalysts are clear: bioleaching column test results, PEA publication, and trial mining permit application progress. For investors willing to engage with early-stage development risk, ValOre offers a large resource, proprietary technology, and a credible pathway to production in a jurisdiction that is increasingly attractive to Western capital.View ValOre Metals' company profile: https://www.cruxinvestor.com/companies/valore-metalsSign up for Crux Investor: https://cruxinvestor.com

    NeurologyLive Mind Moments
    162: Breaking Down INFUSE Trial Data and Real-World Eptinezumab Use

    NeurologyLive Mind Moments

    Play Episode Listen Later Mar 6, 2026 20:37


    Welcome to the NeurologyLive® Mind Moments® podcast. Tune in to hear leaders in neurology sound off on topics that impact your clinical practice.In this Mind Moments episode, Amaal Starling, MD, FAHS, FAAN, joins the podcast to provide clinical perspective on the INFUSE real world study evaluating IV eptinezumab in adults with migraine who previously found one or more CGRP preventive options ineffective, based on data presented at the 2026 Headache Cooperative of the Pacific Annual Conference. Starling, an associate professor of neurology at Mayo Clinic College of Medicine and a study author on INFUSE, discusses how clinicians should interpret the magnitude of benefit in a high burden population and why IV delivery, including rapid and consistent bioavailability, may help explain early and sustained response. The conversation also explores what the findings suggest for real world care and treatment sequencing, how migraine trials can better capture patient experience through outcomes like good days and PGIC, and what precision medicine research could look like next as the field pushes toward predictive modeling and individualized treatment selection.Looking for more Headache & Migraine discussion? Check out the NeurologyLive® Headache & Migraine clinical focus page.Episode Breakdown: 1:20 – Interpreting real world response after prior CGRP preventive failure 4:25 – Mechanistic reasons IV eptinezumab may drive early sustained benefit 6:25 – Clinical implications for earlier, more robust treatment sequencing 8:50 – Neurology News Network  11:20 – Integrating good days and Patient Global Impression scales into migraine trial design 15:30 – Future studies needed to advance precision migraine care The stories featured in this week's Neurology News Minute, which will give you quick updates on the following developments in neurology, are further detailed here: Fenebrutinib Achieves Primary End Point in Phase 3 Head-to-Head Trial vs Teriflunomide in Relapsing MS Praxis Submits NDAs for Ulixacaltamide in Essential Tremor and Relutrigine in SCN2A/SCN8A Developmental Epileptic Encephalopathies Efgartigimod Meets Primary End Point in Phase 3 ADAPT OCULUS Study of Ocular Myasthenia Gravis Thanks for listening to the NeurologyLive® Mind Moments® podcast. To support the show, be sure to rate, review, and subscribe wherever you listen to podcasts. For more neurology news and expert-driven content, visit neurologylive.com.

    echtgeld.tv - Geldanlage, Börse, Altersvorsorge, Aktien, Fonds, ETF
    egtv #451 Krisen, Inflation, Zinsen: Update zum All-Weather-Portfolio von Ray Dalio – mit Christian W. Röhl

    echtgeld.tv - Geldanlage, Börse, Altersvorsorge, Aktien, Fonds, ETF

    Play Episode Listen Later Mar 6, 2026 86:31


    Die Märkte haben in den letzten Tagen wieder gezeigt, wie schnell „Risiko“ zurück auf die Agenda kommt: Geopolitik als Treiber, Energieabhängigkeiten in Asien, Europas strukturelle Schwächen und zugleich die Frage, wie Inflation, Zinsen und Staatsverschuldung in dieses Bild hineinspielen. Tobias Kramer und Christian W. Röhl (Chief Economist von Scalable Capital) ordnen das ein: Was davon ist fundamental? Was ist Momentum? Und warum sind exakte Prognosen bei Zinsen und Währungen in solchen Phasen oft eher Nebelwand als Orientierung? Im zweiten Teil geht es um Struktur, in der Analyse und fürs Vermögen: Tobias und Christian schauen auf Ray Dalios All-Weather-Portfolio als Framework, das Renditetreiber entlang von Wachstum und Inflation denkt. Was hat der Ansatz in den letzten Jahren geliefert? Wo kam die Stabilität her? Welche Bausteine müsste man heute pragmatischer aufsetzen? Ist Gold weiterhin ein Thema? Wie kann man Anleihen vernünftig und risikokonform abdecken? Zum Schluss wird es praktisch: eine verdichtete „Vier gewinnt“-Variante mit klarer und sehr kostengünstiger Rebalancing-Regel (Schwellen statt Kalender) – als Beispiel dafür, wie strategische Asset-Allokation über lange Zeiträume Volatilität und Drawdowns reduzieren kann, auch wenn man dadurch nicht in jeder Phase „optimal“ liegt. Ziel ist wie üblich Orientierung: Nicht unbedingt Recht behalten in fünf Tagen – sondern eine tragfähige Portfolio-Logik über Jahre einsetzen!

    Drama Carbonara
    #326 - DC feat. Sima Dhillon - Flintaxi Unternehmerin - Frauen gestehen: „Ich wollte eine Hexe werden!“

    Drama Carbonara

    Play Episode Listen Later Mar 6, 2026 72:18


    TRIGGERWARNUNG: Sexismus & Tieropfer Christine M. (24) steckt in einer Phase, in der in ihrem Leben scheinbar alles schiefgeht. Im Büro macht sie einen folgenschweren Fehler und wird von ihrem cholerischen Chef zusammengestaucht. Auf dem Heimweg wird sie in der U-Bahn von einem "Sexstrolch" begrapscht – und als wäre das nicht genug, macht ihr Freund Dirk am selben Abend auch noch per Anrufbeantworter Schluss. Ja, wir befinden uns im Jahr 2006 (oder irgendwann davor) Frustriert und verletzt stößt Christine im Fernsehen auf eine Dokumentation über moderne Hexen. Die Idee fasziniert sie: Als Hexe könnte sie stark, unabhängig und unangreifbar sein. Besessen von diesem Gedanken sucht sie im Internet nach Gleichgesinnten und gerät an eine selbsternannte Hexe namens Memra. Schritt für Schritt lässt Christine sich in eine dubiose Szene hineinziehen, zahlt hohe Geldbeträge für angebliche „Ausbildung“ und glaubt schließlich, kurz davor zu stehen, selbst zur Hexe geweiht zu werden. Doch bei einem geheimen Ritual erkennt sie plötzlich, dass sie in einen gefährlichen Betrug hineingeraten ist. Am Ende bleibt ihr eine bittere Erkenntnis: Keine Magie kann ihr Leben retten – nur sie selbst. Danke für diese abgefahrene Story an unseren lieben Fan Sven aus Dresden, der tatsächlich ein altes Heft aus dem Jahr 2006 für uns aufgestöbert hat und sagen wir mal so, it's a ride - more stories to come! ** Dieses Mal ist die tolle Sima Dhillon zu Gast, Taxiunternehmerin und Gründerin des Flintaxi Wien - ein Taxiangebot für FLINTA-Personen (Frauen, Lesben, inter, nicht-binäre, trans und agender Personen), das einen sicheren und respektvollen Fahrraum schaffen soll, insbesondere für Menschen, die sich in herkömmlichen Taxis oder nachts allein unsicher fühlen. Unsere Tatjana hat Sima bei der Kunstperformance „Taxi Tales“ kennengelernt, die die Geschichte der ersten Taxifahrerin Wiens erzählt.  Mehr Informationen zu Sima und dem Flintaxi gibt es auch auf Instagram! Und da es unbedingt mehr FLINTA-Personen braucht, die zukünftig den Taxilenker*innen Beruf ausüben, damit es auch ein breites Angebot geben kann - hier mehr zur Taxilenker*innenausbildung in Wien. ** **Euch hat diese Geschichte gefallen, aufgeregt oder ihr habt euch darin sogar wiedererkannt?** Das interessiert uns brennend! Schreibt uns in Kommentaren über Facebook und Instagram unter @drama_carbonara_podcast. Dort werdet ihr auch die in den Geschichten besprochenen Fotos finden und endlich sehen können, was wir sehen ... Falls ihr noch mehr fantastische Geschichten mit uns lesen wollt, können wir euch schon jetzt versprechen: das Repertoire ist unerschöpflich, wir staunen jedes Mal aufs Neue, was möglich ist. Abonniert Drama Carbonara auf allen gängigen Podcast Plattformen Über Sternchen, Bewertungen und Kommentare freuen wir uns natürlich auch extrem und feiern diese gern auch prominent in unserem Social Media Feed! Jede zweite Folge kommen ja großartige Gastlerser*innen zu uns ins Wiener Drama-Hauptquartier und unterstützt uns mit Interpretationen und Improvisationen. Wenn ihr einen Wunschgast für uns habt oder gern selbst mal vorbeischauen wollt, sagt Bescheid! Wir können nichts versprechen, aber wir freuen uns immer über Vorschläge. Wenn ihr Lust auf Extra-Content habt und euren Lieblingspodcasts auch finanziell unterstützen wollt , dann tut das herzlich gern mit einem Abonnement auf Steady und kommt in den Genuss des kompletten "Drama Carbonara"-Universums! Falls ihr daran interessiert seid, Werbung in unserem Podcast zu schalten, setzt euch bitte mit Stefan Lassnig von Missing Link in Verbindung. Verbindlichsten Dank! **Link zur Podcast Hörer:innen UMFRAGE!Danke für die Mitarbeit und euer wertvolles Feedback :) & hier zur legendären Spotify Drama Carbonara Soundtrack Playlist - folgen folgen folgen!! liebe Freund:innen des unberechenbaren Musik-Algorithmus!

    The Smart Buildings Academy Podcast | Teaching You Building Automation, Systems Integration, and Information Technology

    Power monitoring is no longer just an electrical concern. It directly impacts how your HVAC systems perform, how stable your BAS is, and how much your building costs to operate. As buildings electrify, add EV chargers, convert to heat pumps, and increase server loads, your electrical infrastructure becomes the backbone of performance. If power quality degrades, everything downstream feels it. In this episode, you will explore how electrical data connects to equipment life, demand charges, and system reliability. More importantly, you will see how your BAS can shift your facility from reactive troubleshooting to proactive control. Topics Covered Why power monitoring matters more as buildings electrify Real power, energy consumption, and demand charges explained How power factor and harmonics quietly impact equipment life Phase imbalance, voltage events, and hidden failure risks Using your BAS for demand limiting, load shedding, and peak shaving If you manage HVAC or building automation, understanding power data may be one of the most practical ways to reduce cost and extend equipment life this year.

    Der Tag - Deutschlandfunk
    Flächenbrand im Nahen Osten - Steht eine neue Phase des Krieges bevor?

    Der Tag - Deutschlandfunk

    Play Episode Listen Later Mar 5, 2026 22:30


    Der Bündnisfall ist unwahrscheinlich – auch nachdem die NATO iranische Raketen abgefangen hat. Aber es mehren sich Berichte, dass eine Bodenoffensive bevorstehen könnte. Und: Was kann der "Anti-AfD-Pakt" in Sachsen-Anhalt wirklich leisten? Philipp May

    Tech Disruptors
    Microsoft on Getting Beyond the Pilot Phase

    Tech Disruptors

    Play Episode Listen Later Mar 5, 2026 41:53


    “No great company became a great company because they saved a lot of money,” says Eric Boyd, president of Microsoft's AI platform. “They became a great company because they delivered amazing innovative experiences.” In this episode of Tech Disruptors, Boyd explains to Bloomberg Intelligence Senior Technology Analyst Anurag Rana how Azure OpenAI Service, Azure Machine Learning and Azure AI Foundry fit together. He also discusses what's required to move to broad usage from a pilot: securing enterprise data, retrieving the right context (including “IQ” tooling), evaluating prompts across models and managing costs with techniques like model routing.

    ai microsoft pilot phase iq boyd azure machine learning azure openai service eric boyd
    Happy Shooting - Der Foto-Podcast

    Hausmeisterei Video zur Episode Text-/Audio-/Videokommentar einreichen HS-Hörer:innen im Slack treffen Aus der Preshow Hier ist nämlich Phase, deshalb haben wir Prestrom… Morsen und CBFunk HS Workshops Workshops HS Workshop-Newsletter Statt Werbung DANKE an alle Spender HSFeedback von Thomas: RapidRaw kostenloser RAW Entwickler von Johannes: Ich habe auf jeder Kamera einen HotShoe-Schutz von Frank: Warum berichtet … „#933 – Hintertürchen“ weiterlesen

    Smart Biotech Scientist | Bioprocess CMC Development, Biologics Manufacturing & Scale-up for Busy Scientists
    232: From IND to BLA: The Biologics CMC Decisions That Determine Regulatory Success with Henri Kornmann - Part 2

    Smart Biotech Scientist | Bioprocess CMC Development, Biologics Manufacturing & Scale-up for Busy Scientists

    Play Episode Listen Later Mar 5, 2026 18:16


    How solid is your CMC foundation—and what happens if it cracks under pressure?David Brühlmann welcomes Henri Kornmann, former Head of Biologics Innovation Centre at Ferring Pharmaceuticals. From junior CMC scientist at Merck to leading Ferring Pharmaceuticals' first gene therapy approval for bladder cancer, Henri has moved repeatedly between CMC development, GMP manufacturing, and due diligence across some of the industry's most complex programs.His “house building” approach demystifies CMC's complexity, showing why early diligence paired with regulatory fluency and scientific insight pays dividends for years.Tune in to hear Henri's practical wisdom distilled through real-world analogies:Building a strong CMC foundation in early phases and why later fixes can be costly or impossible (02:45)Scaling up: supplying Phase 3 with the final commercial process, including robustness and supply chain strategies such as dual sourcing critical raw materials (03:23)Process validation explained: FDA's three stages, from control strategy justification to continued verification (05:15)Process Performance Qualification (PPQ): what it is, how many batches are needed, and optimizing timing (07:43)Handling lifecycle changes: maintaining process control, adapting to deviations, and improving systems after regulatory approval (09:34)Managing teams, stakeholders, and cross-functional collaboration in CMC programs (11:49)Importance of good project management, access to scientific expertise, and interpreting guidelines for your specific program (12:27)The “half scientist, half lawyer” analogy for mastering both technical and regulatory aspects (15:08)Smart insight:Never underestimate CMC. If you do, you will pay for it later.If this topic resonates with you, here are a few related episodes where we dive deeper into building strong CMC foundations and avoiding costly development mistakes:Episodes 199 - 200: Mastering Quality by Design: From Product Failures to Commercial Success in Biologics CMC DevelopmentEpisodes 189 - 190: Why Smart Biotech Founders Plan CMC First (While Competitors Burn Cash Later)Episodes 23 - 24: Strategies for Success: Master CMC Development with Gene LeeEpisodes 57 - 58: Crafting a Solid CMC Strategy: Key Factors and Common Pitfalls with Matthias MüllnerConnect with Henri Kornmann:LinkedIn: www.linkedin.com/in/henri-kornmann-9b6869Next step:Need fast CMC guidance? → Get rapid CMC decision support hereSupport the show

    The Essential Oil Scoop
    Ep. 284- 90 Day Reset Month 3: The Renew Phase Explained (How & When to Use the Products)

    The Essential Oil Scoop

    Play Episode Listen Later Mar 5, 2026 31:38


      We are back! p. 284- 90 Day Reset Month 3: The Renew Phase Explained (How & When to Use the Products) is exactly what we are talking about today. We told you we are seeing this through and giving you all that you need to make the best choices possible for your wellness.  So buckle up beautiful, and enjoy learning.  Also..... Get this Book! Link for Essential Emotions book. You need it.  https://aromatools.com/collections/frontpage/products/essential-emotions-14th-edition The Essential Life book here https://essentiallife.com/product/essential-life-10th-edition/ Are you ready to release emotions that have been weighing you down? Book a session today! Book with Vicki: https://vickilebrilla.com/coaching Book with Sarah: https://sarahsepos.com/coaching   Scoop of the Day Please add to your prayers to love yourself more and how you can have more self-care   Diffuser Blend 3 Grapefruit 3 Wild Orange 3 Green Mandarin 3 Tangerine   #90DayReset #RenewPhase #GutHealth #HormoneBalance #HolisticWellness #NaturalDetox #WellnessJourney #BodyRenewal #CleanLiving   Welcome into our little essential oil world where we talk about the physical and emotional support of our essential oils.   Hi friends, don't forget to leave us a review, your feedback is always welcome, and helps this podcast reach more ears. Join us in our New Facebook Community! Connect on Instagram  We upload a brand new episode every Tuesday and Thursday!   Want to learn more about us? theessentialoilscoop.com   Remember to like, share, and subscribe to our podcast so you will be notified every time we upload a brand new episode.  Leave us a review as well, your feedback is always welcome. Also opt-in to our newsletter at https://theessentialoilscoop.com/newsletter   If you have any questions or have subject ideas you would like us to cover please email us at theessentialoilscoop@gmail.com   Tag us on socials using #theessentialoilscoop #essentialoilpodcast #oilpodcast   Disclaimer:  Welcome to The Essential Oil Scoop Podcast. We want to remind our listeners that the information provided in this podcast is for educational purposes only and should not be considered as a substitute for professional medical advice, diagnosis, or treatment. The use of essential oils is a personal choice and should be done at your own risk. We are not medical professionals and cannot diagnose, treat, or prescribe any medical condition. Please consult with a qualified healthcare provider before using any essential oils or making changes to your healthcare routine. Any information or opinions expressed in this podcast are those of the hosts and guests and do not necessarily reflect the views of any particular organization. Thank you for listening.

    Bussin' With The Boys
    A Surprise Gender Reveal, The NO Phase + Dealing With Your Kids Sports Failure | For The Dads

    Bussin' With The Boys

    Play Episode Listen Later Mar 4, 2026 143:19 Transcription Available


    In this episode of For The Dads with Former NFL Linebacker Will Compton, hosts Will and Sherm discuss Rue going through the NO phase, talk through their favorite recommendations for dinner in Nashville, and break down a brutal voicemail from a Dad trying to help his son with being cut from his first sport — all while keeping the episode fun, fresh and of course, under an hour. The episode kicks off with an amazing gender reveal before they dive into some hilarious conversations, including: A potential suitor for our dating request Sherm talks about his date night with the Wifey PTFitto has taken over Other highlights include: Chef reminds Will we HAVE to keep it under an hour An email of maybe our most handy member of PT6

    The Midpacker Podcast
    MidPacker Pod Field Notes – Ep 002 | 9 Weeks to Hellbender: Finishing the Tempo Block and Starting the Endurance Phase

    The Midpacker Podcast

    Play Episode Listen Later Mar 4, 2026 41:29


    MidPacker Pod – Field Notes Ep 2Title: Nine Weeks to HellbenderWith nine weeks until the Hellbender 100, Troy Meadows checks in on his training as he finishes a tempo block and begins the endurance phase. In this episode of MidPacker Field Notes, Troy shares snow day miles in Asheville, plans for a mini training camp, trail work at Snooks Nose, fueling strategies, and a shoutout to a listener preparing for her first ultra.The MidPacker Pod is part of the Freetrail network of Podcasts.Join the Newsletter at: ⁠MidPack Musings SubStack⁠⁠Support the MidPacker Pod on ⁠Patreon⁠.⁠Check Out MPP Merch Make sure you leave us a rating and review wherever you get your pods.Looking for 1:1 Ultra Running Coaching? Check out Troy's Coaching PageSTOKED TO PARTNER WITH  HYPERLYTE LIQUID PERFORMANCE - 10% off your orderTRAINING PEAKS - 20% off a premium annual subscriptionPLAY ON RELIEF - 20% off your first orderVACATION RACES - 15% off any Ultra, Half Marathon, or TrailfestUSE PROMO CODE MIDPACKER FOR A SWEET DISCOUNTWAHOO FITNESS -  Use Code MIDPACK: When you pick up a Wahoo KICKR RUN get a free TRACKR Heart Rate Monitor chest strap. Remember to add the TRACKR to the cart and the code will apply to discount.“It's not about what you do on a daily basis, it's about how you're stacking and showing up consistently over a really long time horizon.”In Episode 2 of MidPacker Field Notes, Troy Meadows shares a quick update on his Hellbender 100 training. With nine weeks to race day, he reflects on finishing a tempo block and shifting into endurance-focused training.Troy previews an upcoming mini training camp designed to simulate race fatigue and dial in pacing, fueling, and gear. He also shares updates from a Snooks Nose trail work day and explains why the original Hellbender course may still be another year away from returning.Training HighlightsTempo block completeKey workout: 4 x 10 minute uphill intervalsNine weeks until Hellbender 100Mini training camp planned six weeks outTrainingPeaks used to structure trainingFueling with Hyperlyte Liquid PerformanceRecovery supported with PlayOn Relief PodsCommunity ShoutoutOlivia Farr – preparing for her first 55K and the Mount Mitchell Heartbreaker after returning to running following pregnancy.Relevant Linkshttps://hellbender100.comhttps://www.tanawhaadventures.com/mountmitchellheartbreakerhttps://www.g5trailcollective.org/oldfortPartner Links: Hyerlyte Liquid Performance - https://www.hyperlyteliquidperformance.comMade by the ultra-endurance athlete, for the ultra-endurance athlete.More Carbs, More Dirt, More Miles.Use the code MIDPACKER for 10% off your individual order and 10% off your first subscription order.“The Kid” Hans Troyer DocumentaryPlayOn Relief - https://playonrelief.com All Natural, Fast Acting, Long Lasting, Targeted ReliefUse MIDPACKER for 20% off your first orderTraining Peaks - https://www.trainingpeaks.com/midpackerA training app as versatile as you. Use MIDPACKER at checkout for 20% off an Annual Premium SubscriptionVacation Races - https://www.vacationraces.com/Epic Races on public lands near the most iconic National Park in the US.Use MIDPACKER at checkout for 15% the registration of any Ultra, Half, or TrailfestWahoo Fitness - https://www.wahoofitness.comKICKR RUN It's not running indoors. It's running, reimagined.Buy the Wahoo KICKR RUN use code MIDPACK to get a free TRACKR Heart Rate Monitor chest strap. ⁠Run Trail Life⁠ - https://runtraillife.com/Find Official MPP Merch on RTL!!.⁠Freetrail⁠ - https://freetrail.com/Visit Freetrail.com to sign up today.Hellbender 100, ultrarunning training, endurance block, tempo training, uphill intervals, trail running, winter running, TrainingPeaks, Hyperlyte Liquid Performance, PlayOn Relief Pods, Mount Mitchell Heartbreaker, ultra coaching, endurance training, trail stewardship, Snooks Nose Trail

    I Love Recruiting
    The One Sentence Every Group Coaching Offer Needs (And Most Coaches Skip)

    I Love Recruiting

    Play Episode Listen Later Mar 4, 2026 21:02 Transcription Available


    You don't need a better funnel to launch your group coaching program. You need one sentence. And if you can't say it clearly to a stranger at a dinner table, your offer isn't ready — no matter how good your coaching actually is. This is Part 1 of a 7-part series on scaling from one-on-one to one-to-many, and Adam and Jess are starting with the thing almost every coach skips.What You'll LearnWhat "payoff language" means and why vague, aspirational promises like "build a legacy" are costing you clientsThe one-sentence formula for a coaching offer that attracts buyers and filters out everyone elseWhy leading with your credentials is the fastest way to lose someone who actually needs you right nowThe difference between an attainable payoff and an aspirational one — and why only one of them convertsHow getting crystal clear on your offer transformation is the fastest cure for imposter syndromeEpisode SummaryThis is Part 1 of ILC's 7-step framework for transitioning your coaching business from one-on-one to a group or one-to-many model. And Adam and Jess are starting at the foundation most coaches never build: your payoff.Your payoff is the specific, one-sentence answer to: who do you help, what is their problem, and what is your solution? Think headache relief — not "become the best version of yourself." If someone is in pain and shopping for a solution, they need to hear plain, explicit language that tells them you have what they need. Flowery, idealized language doesn't land when someone's head hurts.Adam and Jess walk through a simple three-part payoff formula: start with your avatar (almost always a past version of yourself), name the exact problem they have, and articulate the solution you have already delivered — not one you aspire to deliver someday. That last distinction matters. A payoff rooted in your own lived experience is what gives you the competence and confidence to show up without constantly second-guessing yourself.They also bring in Donald Miller's StoryBrand framework here — the shift from being the hero of your own story to becoming the guide. When your payoff is grounded in empathy and proven experience, imposter syndrome loses its grip. You stop trying to prove yourself and start pointing people toward the outcome you already know how to deliver.Everything in a one-to-many offer is built from the payoff. This is where it starts.Key Quote"Everything is built from the payoff. It's not everything is built from the person." — JessResources + LinksBuilding a StoryBrand by Donald Miller (hero vs. guide framework, cognitive dissonance) amzn.to/3N9coPTREAL Coach Method Blueprint — ILC's Phase 2 Checklist: "My payoff is specific, realistic, and easy to explain in one sentence."Get Paid to Coach PDF ilovecoachingco.com/get-paid-to-coachILC Call to ActionIf your payoff isn't clear yet, start here. Grab the free Get Paid to Coach PDF at ilovecoachingco.com/get-paid-to-coach — it walks you through this exact process whether you're still in one-on-one or ready to build something bigger. Clear payoff, clear business. That's where everything starts.

    State Shifters
    SPP197: The 4-Phase Initiation That's Helped 1,000s of Men Love & Lead Better In Their Relationships

    State Shifters

    Play Episode Listen Later Mar 4, 2026 14:43


    Discover the four-phase initiation that's transforming how men lead in their relationships and life. In this video, I break down the roadmap I've used with clients and my own 10-year relationship to help men step into emotional clarity, build connection, and embody true masculine energy. From leading with direction, creating safety and connection, mastering embodiment practices, to communicating with clarity, you'll learn actionable steps to deepen intimacy, reduce conflict, and become the man you want to be.Whether you're struggling with emotional disconnection or ready to elevate your relationships and personal growth, this is the guide you've been looking for.WORK WITH ME

    Core EM Podcast
    Episode 220: Post-ROSC Care

    Core EM Podcast

    Play Episode Listen Later Mar 3, 2026


    We explore how to refine and optimize care in the vital minutes following ROSC. Hosts: Jonathan Elmer, MD, MS Brian Gilberti, MD https://media.blubrry.com/coreem/content.blubrry.com/coreem/Post-ROSC_care.mp3 Download Leave a Comment Show Notes Core EM Modular CME Course Maximize your commute with the new Core EM Modular CME Course, featuring the most essential content distilled from our top-rated podcast episodes. This course offers 12 audio-based modules packed with pearls! Information and link below.  Course Highlights: Credit: 12.5 AMA PRA Category 1 Credits™ Curriculum: Comprehensive coverage of Core Emergency Medicine,  with 12 modules spanning from Critical Care to Pediatrics. Cost: Free for NYU Learners $250 for Non-NYU Learners Click Here to Register and Begin Module 1 I. Phase 1: Stabilization (Minutes 0–10) The “Rearrest” Window & Pathophysiology High-Risk Period: Rearrest rates reach 30% within the first minutes post-ROSC. Shock Incidence: Two-thirds of patients develop profound hypotension/shock as initial resuscitative efforts subside. Catecholamine Washout: Super-physiologic “code-dose” epinephrine (1mg IV) typically wears off within ~3 minutes post-ROSC, leading to predictable hemodynamic collapse. Secondary Injuries: Evaluate for “CPR-induced trauma” (blunt thoracic trauma, rib fractures, pneumothorax, liver/splenic lacerations). Immediate Resuscitative Actions Vascular Access: Transition rapidly from IO to reliable IV access within 1–2 minutes. Prioritize Intraosseous (IO) placement within 5 minutes if IV attempts fail; intra-arrest data suggests no significant difference in early outcomes. Vasoactive “Bridge”: Maintain a “bolus-dose” pressor at the bedside for immediate push-dose titration. Options: Phenylephrine, dilute Epinephrine, or dilute Norepinephrine (titrated to effect rather than rigid dosing). Physician-Specific Task: Arterial Line: Goal: Placement within 5 minutes of ROSC. Preferred Site: Femoral (by landmarks/blind if necessary) for speed; should be a 80 mmHg. The BOX Trial Nuance: While the BOX trial showed no difference between MAP 63 vs. 77, its cohort (Denmark) had exceptionally high survival rates (70% back to work) and short response times, which may not generalize to North American populations with lower shockable rhythm incidence. Permissive Hypertension: If the patient is “self-driving” to higher pressures, do not aggressively lower them, as this may be a physiologic demand for cerebral blood flow. Ventilation and Oxygenation PaCO2 Management: Target: High-normal to slightly hypercarbic (45–55 mmHg). Rationale: Avoid accidental hyperventilation (PaCO2

    On The Pen: The Weekly Dose
    Gray Market GLP-1 Is Booming Branded Access is Broken

    On The Pen: The Weekly Dose

    Play Episode Listen Later Mar 3, 2026 26:23


    Send a textEpisode Summary (Short Version):This week on On The Pen, Dave breaks down the rapid changes reshaping GLP-1 access — from new federal reforms targeting PBMs and possible FDA limits on compounded semaglutide, to Walgreens and Amazon launching cash-pay weight loss clinics.As insurance denials continue and out-of-pocket costs rise, patients are stuck between a shifting policy landscape and a growing direct-to-consumer market. Plus, an AI-designed oral GLP-1 enters Phase 3 trials, signaling how fast obesity medicine is evolving.Visit TRYSHED.COM to learn more today! Use CODE OTP25 to save 25%!

    The Making of a Dental Startup
    A Walk, A Miracle, and a New Menu

    The Making of a Dental Startup

    Play Episode Listen Later Mar 3, 2026 40:00


    In this raw, "on-the-go" episode, Brian and Ashley take you on a Thursday afternoon walk in California to discuss the most intense season of their lives. Recorded just after receiving life-changing medical imaging results, this conversation bridges the gap between the clinical "battle" and the human "journey."From the "hangover" of chemotherapy to a radical shift in nutrition, this is a deep dive into what it means to "make" a life when the foundation is shaken.

    Heart Dive with Kanoe Gibson
    Flight Or Fight in 1 Samuel 13-14 | Real Conversations | Heart to Heart | Ep. 006

    Heart Dive with Kanoe Gibson

    Play Episode Listen Later Mar 3, 2026 44:12


    Welcome to Heart Dive's Heart to Heart Conversations, where we navigate modern-day issues with God's Word.Heart Work: https://drive.google.com/file/d/1rOtrlNZihVvv6IhacuYK3HPN8sXzMCEx/view?usp=drive_linkH2H: Episode 006Fight or Flight in Leadership | 1 Samuel 13-14 | Heart Dive PodcastSaul hid behind fear. Jonathan walked in faith. What's the difference? Peace.In this roundtable on 1 Samuel 13-14, Kanoe, Holly, and Wynter break down how a dysregulated heart leads to impulsive decisions, control tactics, and spiritual shortcuts while a God-trusting heart leads to patience, clarity, and obedience.Peace is not passive. Peace is evidence of trust.#HeartDive #BibleStudy #1Samuel #FaithOverFear #ChristianWomen #BiblStudyForWomen #ShortsKEY TOPICS:Saul's insecurity and hidingComparison between Saul and DavidHeart shifts in biblical charactersLessons on joy and peace from 1 Samuel 13-14Help keep our Bible study resources free by supporting as a Heartkeeper here: https://heartdive.org/give/Join us in our daily Bible study!PHASE 1: heartdive.org/startHEART DIVE LOBBY (Facebook Community): https://www.facebook.com/share/g/1BK2GvLZbo/?mibextid=wwXIfrVISIT OUR SHOP: heartdiveshop.comFREE RESOURCES: https://drive.google.com/drive/u/0/mobile/folders/1Tvms_gB-OWMum61DiCXvFV8R8jKXpIVIMy Bible Notes: https://heartdive.org/daily-notes-with-kanoe/Amazon Link: https://www.amazon.com/shop/kanoegibson/list/1ED3COSB79TAQ?ref_=aipsflistLOGOS Software affiliate link: http://www.logos.com/heartdiveFree Reading Plan and Daily Newsletter sign up: http://heartdive.org/newsletterLink to recommended Bibles: https://heartdive.org/recommendations/

    CruxCasts
    New Found Gold Corp. (TSXV:NFG) - Production Margins Support 100,000m Queensway Program

    CruxCasts

    Play Episode Listen Later Mar 3, 2026 14:10


    Interview with Keith Boyle, CEO, New Found GoldOur previous interview: https://www.cruxinvestor.com/posts/new-found-gold-tsxvnfg-permitted-infrastructure-accelerates-path-to-gold-production-9383Recording date: 2nd of March 2026New Found Gold is executing a calculated transformation from exploration company to near-term producer under CEO Keith Boyle, who joined the company one year ago with a clear mandate: convert five years of exploration work into cash flow generation.The cornerstone of this strategy was the acquisition of Maritime Resources, which delivered two critical assets—the producing Hammerdown mine and the permitted Pine Cove Mill. Hammerdown achieved first pour in November 2025 and is ramping to steady-state production, generating immediate cash flow at current gold prices. Meanwhile, the Pine Cove Mill, which restarted in March 2025, will be expanded from 700 to 1,400 tons per day capacity to process material from both Hammerdown and the flagship Queensway project.This acquisition-driven approach solves a fundamental challenge: accelerating Queensway production by 2-3 years. Building an on-site mill would require in-pit tailings deposition, significantly extending permitting timelines and forcing continuous dilutive financing. Instead, New Found Gold plans to ship Queensway material 270 kilometers along the Trans-Canada Highway to Pine Cove by the end of 2027.The economics prove compelling. Queensway's Phase 1 targets 700 tons per day at grades of 9-10 grams per ton gold, with all-in sustaining costs of $1,300 per ounce. Combined trucking and processing costs approximately one gram per ton, leaving substantial margins at current gold prices above $5,000 per ounce. The company projects over $250 million in free cash flow during the first four years, which will fund construction of an on-site mill for Phase 2 expansion.Recent grade control drilling on 5x5 meter centers addresses previous concerns about "nuggety" mineralization, revealing instead consistent gold distribution as fine flakes throughout high-grade shoots. This systematic de-risking, combined with visible gold at surface in the Iceberg zone, positions Queensway for low-capital-intensity production start-up while the company continues district-scale exploration with 100,000 meters of drilling planned for 2026.Learn more: https://www.cruxinvestor.com/companies/new-found-goldSign up for Crux Investor: https://cruxinvestor.com

    Learn to be the Healer in your Home
    Burnout, Hormones & Midlife Reset: Practical Support for Perimenopause

    Learn to be the Healer in your Home

    Play Episode Listen Later Mar 3, 2026 58:05


    In this episode of the Essential Wellness Podcast, we explored how to navigate burnout and perimenopause with practical, natural solutions. Hosted by Aisha Harley, the conversation featured Arin Fugate, Dr. Josie, Dr. Mica & Dianne DelReyes LA.c  who discussed early signs of burnout, hormonal shifts, genetic detox considerations, and supportive essential oil and supplement protocols. Arin shared her personal journey through midlife exhaustion, brain fog, sleep disruption, and weight gain — highlighting how chronic stress, caffeine reliance, post-COVID recovery, and genetic factors like MTHFR mutations compounded her symptoms. The discussion emphasized recognizing early warning signs and implementing simple, supportive habits before deeper depletion occurs.

    The Mortal Realms - A Warhammer: Age of Sigmar Podcast
    Ossiarch Bonereapers v2 - Story Phase - Ep 102

    The Mortal Realms - A Warhammer: Age of Sigmar Podcast

    Play Episode Listen Later Mar 2, 2026 177:01


    In this episode we cover the lore of the Ossiarch Bonereapers Battletome. Get ready for a whole lot of bureaucracy, bone-snapping, and the unholy fusion of disparate souls. And then if we have time, we'll talk all about those Ossiarchs!   ***Thanks to GW for providing this book for us to review on the show!*** Show Notes Time Stamps What we've been up to: 3:57 The Story Phase: 18:30 Links (some links may redirect to our affiliate partners)  The Ossiarch Bonereapers Battletome can be purchased at… Hardcover at Games Workshop Contact You want to get a hold of us? Of course you do - here's how: Website: themortalrealms.com It'd really help us help you to get a review on iTunes or wherever else you listen to podcasts. Find us in your app, or head over to themortalrealms.com/review and tell us what you think. Youtube: youtube.com/themortalrealms Patreon: patreon.com/themortalrealms Twitter: @themortalrealms Davy: @Red_Zeke Paul: @pjschard Eric: @stonemonkgamer Aaron @dosaceos Josh: @jearrington  Will: @ageofSevvir Facebook: facebook.com/themortalrealms Email: mortalrealms@gmail.com Discord: themortalrealms.com/discord Shirts: https://www.themortalrealms.com/shirts Goodreads Book Club: themortalrealms.com/bookclub

    Dark Side of Wikipedia | True Crime & Dark History
    Nick Reiner Case: Why "Not Guilty" Doesn't Mean What You Think—Legal Analysis

    Dark Side of Wikipedia | True Crime & Dark History

    Play Episode Listen Later Mar 1, 2026 29:33


    Nick Reiner pleaded not guilty to two counts of first-degree murder. The headlines wrote themselves. Most of them missed the point.In California criminal procedure, a not guilty plea at arraignment is a placeholder—not a declaration of innocence. If the defense intended to claim Nick didn't commit the killings, they'd say so. They didn't. What they're doing is preserving options while psychiatric evaluations continue and strategy crystallizes.Here's how California insanity defense works: if you want to claim you were legally insane at the time of the crime, you enter a dual plea—not guilty AND not guilty by reason of insanity. The court then bifurcates your trial. Phase one determines guilt. Phase two, if needed, determines sanity. The single not guilty plea suggests the defense hasn't committed to that path yet.Three doors remain open:M'Naghten insanity. Prove Nick didn't understand what he was doing or didn't know it was wrong. Legal experts are skeptical. He was reportedly arguing with his father at a party hours before the killings—suggesting awareness of conflict and context.Diminished actuality. Use his documented schizoaffective disorder and reported medication changes to argue he couldn't premeditate. This doesn't eliminate guilt—it reduces the charge. First-degree becomes second-degree or manslaughter.Incompetence to stand trial. Halt proceedings entirely until treatment restores Nick's ability to participate in his defense.Meanwhile, Jake, Romy, and Tracy Reiner face something the legal system has no category for: being mourners, crime victims, and the accused's family simultaneously. Sources say they've cut Nick off completely. Sources also say they oppose the death penalty. Whether prosecutors honor that preference remains to be seen.Join Our SubStack For AD-FREE ADVANCE EPISODES & EXTRAS!: https://hiddenkillers.substack.com/Want to comment and watch this podcast as a video? Check out our YouTube Channel. https://www.youtube.com/channel/UC8-vxmbhTxxG10sO1izODJg?sub_confirmation=1Instagram https://www.instagram.com/hiddenkillerspod/Facebook https://www.facebook.com/hiddenkillerspod/Tik-Tok https://www.tiktok.com/@hiddenkillerspodX Twitter https://x.com/TrueCrimePodThis publication contains commentary and opinion based on publicly available information. All individuals are presumed innocent until proven guilty in a court of law. Nothing published here should be taken as a statement of fact, health or legal advice.#NickReiner #RobReiner #MicheleReiner #TrueCrimeToday #NotGuiltyPlea #CaliforniaLaw #InsanityDefense #LegalAnalysis #Parricide #HiddenKillers

    Danny, Dave and Moore
    Hour 1: Can Mariners superstar Julio Rodriguez skip the slow start phase of his season? 

    Danny, Dave and Moore

    Play Episode Listen Later Feb 28, 2026 43:59


    Bob and Dave break down what they expect to see from Colt Emerson over the course of Mariners Spring Training, they look at why Julio might finally be able to skip the slow start phase of his season, they discuss which positions the Seahawks need to focus on in the 2026 NFL Draft, and they ask if they owe Sam Darnold an apology. 

    CNN News Briefing
    Bill Clinton Deposition, Federal Anthropic Phase Out, NASA's Moon Landing Changes and more

    CNN News Briefing

    Play Episode Listen Later Feb 27, 2026 6:44


    We start with details on former President Bill Clinton's testimony to lawmakers in their Jeffrey Epstein investigation. The US ambassador to Israel gave an urgent warning over a potential US military strike on Iran. President Donald Trump made a major move against an American AI company. The father of a teenage Georgia school shooter took the stand in his own defense. Plus, why NASA's plans to put man back on the moon will look differently. Learn more about your ad choices. Visit podcastchoices.com/adchoices