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Listener feedback on non-culprit PCI in STEMI, a major cardiac result in patients on hemodialysis, news on GLP-1 agonists, a dubious stroke trial, and an AHA preview are the topics John Mandrola, MD, discusses in this week's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I Listener Feedback Meta-analysis of MI as a surrogate https://pubmed.ncbi.nlm.nih.gov/34694318/ Compare Acute Trial https://www.nejm.org/doi/full/10.1056/NEJMoa1701067 DANAMI-3–PRIMULTI 10.1016/S0140-6736(15)60648-1 External Link CULPRIT-SHOCK https://www.nejm.org/doi/full/10.1056/NEJMoa1710261 II Huge Cardiac News for Patients with ESRD PISCES article EMBARGOED Till 1130 AM EST PISCES Trial www.nejm.org/doi/full/10.1056/NEJMoa2513032 REDUCE-IT Trial https://www.nejm.org/doi/full/10.1056/NEJMoa1812792 STRENGTH Trial https://jamanetwork.com/journals/jama/fullarticle/2773120 FISH trial https://jamanetwork.com/journals/jama/fullarticle/1150094 III Obesity Agents White House announces deal with Lilly and Novo on GLP-1 drugs https://www.reuters.com/business/healthcare-pharmaceuticals/novo-lilly-shares-rise-trump-obesity-drug-deal-nears-2025-11-06/ Amylin Agonists Amylin Analog Eloralintide Reduces Weight in Phase 2 Trial https://www.medscape.com/viewarticle/amylin-analog-eloralintide-reduces-weight-phase-2-trial-2025a1000uqf Eloralintide Phase 2 Study https://doi.org/10.1016/S0140-6736(25)02155-5 GLP-1 Comparisons SURMOUNT-5 Trial https://www.nejm.org/doi/10.1056/NEJMoa2416394 Tirzepatide vs Semaglutide in 10-year CVD Risk Reduction https://doi.org/10.1093/ehjopen/oeaf117 IV A Problematic Trial in Stroke Care LAMP trial https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2840370 V AHA Preview AHA 2025: Mandrola's Four Trials to Look For https://www.medscape.com/viewarticle/aha-2025-mandrolas-four-trials-look-2025a1000u80 You may also like: The Bob Harrington Show with the Stephen and Suzanne Weiss Dean of Weill Cornell Medicine, Robert A. Harrington, MD. https://www.medscape.com/author/bob-harrington Questions or feedback, please contact news@medscape.net
Show Features: Internet Is Undefeated, Blooper Reel and VoicemailsSocials: @DaveandMahoney Voice Mail: 833-Yo-Dummy https://www.twitch.tv/daveandmahoney Additional Content: daveandmahoney.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Are you wayy too competitive? We laugh so hard talking about our embarrassing phases! Are you a part of a social media group? Snitches get tickets .. Morgan Wallen tickets! We end the show playing the list! See omnystudio.com/listener for privacy information.
Are you wayy too competitive? We laugh so hard talking about our embarrassing phases! Are you a part of a social media group? Snitches get tickets .. Morgan Wallen tickets! We end the show playing the list! See omnystudio.com/listener for privacy information.
We present the eighteenth episode of Eatbrain Radio Season 2, your guide to the dark side of drum and bass! Grimey, dutty and disgusting all the way! Hosted by @5ha5h label// facebook.com/Eatbra1n twitter.com/eatbrain_now instagram.com/eatbrain eatbrain.net Tracklist // 1. Akov & TR Tactics – Reflections [Hanzom Music] 2. Pythius – Inquisition [Blackout Music] 3. Raido & Symplex – Evil Laugh [Eatbrain] 4. Receptor – Punks (Gydra Remix) [Evolution Chamber] 5. Redpill – Bass Infection [Darkshire Sound] 6. Agressor Bunx – Violence [Eatbrain] 7. Tantron & Wiguez feat. Moneo – Alas De Cera [DUB] 8. Osyrus – The Ceremony [Murmuration Records] 9. MNDSCP – We Are Your Friend [Eatbrain] 10. Mefjus & InsideInfo – Mythos [Virus Recordings] (Throwback) 11. Phase & Thread – Need This Shot [Overview Music] 12. Ray Volpe – See You Drop (Audio Remix) [Patreon Exclusive] 13. Burr Oak – Running Next To The Bison (Tesseracts Remix) [Eatbrain] 14. Meph & Karpa – Malice [Darkshire Sound] 15. MV & Deadfussion – The Collaboration [Kosenprod] 16. Mandidextrous & Matt Scratch – Telekinesis [Neuroheadz] 17. Akrom – Phoenix [Skamele Recordings] 18. Ill-Fated – Wicca [Stonx Music] 19. A-Cray – Keep Hiding VIP [Cray Tunes] 20. NOCASE – HARDCORE [Neurotic] (Free Download) 21. Ekwols & HRSPX – The Vigil Abyss [Evolution Chamber] 22. TRCD – The Vortex [VTO Records] 23. Bodrak – Atomic [Paperfunk Recordings] 24. Transforma – Shipwrecked [Warlock Audio] 25. Hoax – Genesis [Hospital Records]
Nach einer kurzen Phase, in der Klimaschutz eine zentrale Rolle in der politischen Debatte einnahm, gerät das Thema wieder ins Hintertreffen. Programme werden gestrichen, Gelder gekürzt. Kann Europa unter diesen Vorzeichen bei der bevorstehenden Weltklimakonferenz im brasilianischen Belém noch Vorreiter sein?Es diskutieren die Europaabgeordneten Lena Schilling (Grüne), Anna Stürgkh (NEOS) und Günther Sidl (SPÖ) mit der Leiterin des FALTER-Naturressorts, Katharina Kropshofer, und Raimund Löw. Hosted on Acast. See acast.com/privacy for more information.
Ever had a brilliant idea that never made it past your brain? Or watched a dream die because someone poked too many holes in it before you even had a chance to build it?In this episode of Ambitious, George Bryant is back to teach one of the most powerful frameworks I've ever learned. This is the Dream Storming model, originally created by Walt Disney to bring Disneyland to life. We're breaking down the three core buckets (Dreamer, Builder, and Protector), the exact rules for each state, and how to recognize which bucket you naturally live in versus which one you go to when triggered.But here's where it gets really good: this framework isn't just for your business. George and I get vulnerable about how we use this in our long-distance relationship, how it's transformed the way we communicate during conflict, and why understanding someone's dominant state can completely shift the dynamic in your partnerships, friendships, and even with your kids.00:00 Introduction12:25 The Walt Disney Dream Storming Story18:09 Applying the Dream Storming Model33:50 Understanding the Dreamer Bucket34:32 Transitioning to the Builder Bucket35:04 Entering the Protector Bucket35:22 Applying the Dream Storming Process36:02 Facilitating Dream Storming with Teams36:40 The Importance of Discipline in Dream Storming45:41 Interpersonal Applications of Dream Storming50:29 The Power of Divergent Thinking53:31 Recognizing Natural and Triggered States01:05:08 Understanding the Protector Mode01:05:50 Navigating Conversations with Awareness01:12:03 Applying the Framework in Personal and Professional LifeConnect with George: InstagramWebsite To join the Ambitious Network for free, click HERE. To connect with Kate on Instagram, click HERE. To apply for ITI, click HERE.To submit a question to be answered on the podcast, click HERE.
Kodal Minerals PLC's (AIM:KOD) CEO Bernard Aylward talked with Proactive's Stephen Gunnion about the officiall opening of the Bougouni Lithium Project by Mali's president, General Assimi Goïta. Aylward confirmed that Kodal is now transporting its first spodumene concentrate, with around 10,000 tonnes already at port and a first shipment of 30,000 tonnes expected by late November or early December. He noted that the company will receive 95% of the cargo value once it is loaded, putting first revenues on track for early December. He described the visit President Goïta and other dignitaries as a moment of pride. "It was a great reception by the community and our team, very justifiably proud with what we've done in Mali,” he said. Looking ahead, Kodal has several development plans, including further drilling at Boumou and Sogola-Baoulé, and completing a Phase 2 study for a flotation plant. Aylward emphasized that the Bougouni project has a projected life of more than 15 years. Visit Proactive's YouTube channel for more company interviews and updates. Don't forget to like the video, subscribe to our channel, and turn on notifications for future content. #KodalMinerals #LithiumMining #BougouniProject #BatteryMetals #MaliMining #Spodumene #LithiumStocks #MiningInvestment #ResourceDevelopment #ProactiveInvestors
Im Interview mit Eric M. Lang, einem der bekanntesten Brettspielautoren, wurden viele spannende Aspekte seines Lebens und seiner Karriere behandelt. Lang ist bekannt für seine erfolgreichen Spiele wie "Blood Rage", "Cthulhu: Death May Die" und "Marvel United". Er erzählt, dass seine Leidenschaft für Brettspiele bereits in seiner Kindheit begann, als er viel Zeit mit seiner Großmutter in Deutschland verbrachte, die ihm Spiele wie "Phase 10" und "Stratego" beibrachte. Obwohl seine Familie deutsche Wurzeln hat, wuchs er in Kanada auf und sprach zunächst Deutsch, bevor er Englisch lernte. Eric M. Lang schildert, wie er ursprünglich Musik machen wollte, insbesondere Rock-Gitarrist werden wollte, inspiriert von deutschem Thrash Metal. Diese Leidenschaft wandelte sich, als er mit 16 Jahren Dungeons & Dragons entdeckte, was seinen Weg als Spieleautor entscheidend beeinflusste. Er begann, eigene Rollenspiele zu gestalten und hatte schon früh ein starkes Bedürfnis, kreativ zu sein. Mit 19 Jahren kam er in Kontakt mit dem Bereich der Sammelkartenspiele und gründete bald darauf seinen eigenen Verlag. Sein Durchbruch kam 2002 mit der Zusammenarbeit mit Fantasy Flight Games, wo er das "Game of Thrones Collectible Card Game" entwarf. Die darauffolgende Erfolgsgeschichte des Unternehmens half ihm, seine kreativen Ambitionen zu verwirklichen. Eric sprach auch über sein erstes Spiel in Essen 1996, das den Grundstein für seine Karriere legte und ihm die Möglichkeit gab, von anderen Verlagen zu lernen. Das Gespräch wandte sich dann den Projekten zu, an denen Lang gearbeitet hat, einschließlich seiner Arbeit mit Cool Mini or Not, wo das Spiel Blood Rage entstand. Interessanterweise beschreibt Eric M. Lang die Entstehung von Blood Rage als einen glücklichen Zufall. Er wollte eine kreative und persönliche Verbindung zu dem Spiel schaffen, was sich letztendlich als einer seiner größten Erfolge herausstellte, als es auf Kickstarter große Unterstützung fand. In der zweiten Hälfte des Interviews sprach Eric M. Lang über seine aktuelle Position bei Hasbro, wo er verstärkt zusammenarbeiten möchte. Seine Ambitionen mit Hasbro betreffen nicht nur seine eigenen Spiele, sondern auch die Entwicklung anderer Titel, an denen er redaktionell mitwirkt. Eric verfolgt das Ziel, so viel Inhalt wie möglich in eine Box zu packen, was in seinem aktuellen Projekt "Leben in Retarra" und dessen Erweiterung "Moonrise" deutlich wird. Eric M. Lang legt großen Wert darauf, dass die Spiele, die er gestaltet, sowohl strategisch tiefgründig als auch zugänglich sind. Abschließend äußerte Eric M. Lang seine Zukunftspläne und die Wichtigkeit von Qualität über Quantität bei der Spieleentwicklung. Er möchte sich auf die Erstellung von weniger, aber dafür bedeutungsvolleren Spielen konzentrieren, während er weiterhin an neuen Projekten arbeitet, die er zuerst Hasbro präsentieren wird. Insgesamt hinterließ das Interview einen tiefen Eindruck von Eric M. Langs Werdegang und seinen Plänen für die Zukunft in der Brettspielbranche.Euer FeedbackIhr habt Feedback zu dem Podcast und Themen- oder Gastwünsche? Schreibt uns an podcast@brettspiel-news.de oder auf Facebook oder Instagram. Außerdem könnt ihr auf unserem Discord Server vorbeischauen und den Podcast auch auf Youtube anhören.
Thu, 06 Nov 2025 13:42:00 +0000 https://jungeanleger.podigee.io/2732-wiener-borse-party-1028-atx-etwas-fester-frequentis-uberholt-at-s-zuruck-verbund-mit-starker-phase-und-gelb-legt-gelb-zuruck 062c0eab66a16f2019654b67d14e304b Die Wiener Börse Party ist ein Podcastprojekt für Audio-CD.at von Christian Drastil Comm.. Unter dem Motto „Market & Me“ berichtet Christian Drastil über das Tagesgeschehen an der Wiener Börse. Inhalte der Folge #1028: - ATX etwas fester - Frequentis überholt AT&S zurück - O-Ton Hans Lang, jetzt bei Reploid, als Teaser für Dienstag - Zahlen von Addiko Bank - CPI Europe scheint zu drehen - Research zu Kontron, Verbund und AT&S - Vintage zu Verbund-Wanderpokal, Michael Tojner, Immoeast, RBI - Partytalk: Gelb legt Gelb zurück - DAX neutral, Zalando gesucht - mehr dazu im Podcast Links: - Börsepeople morgen: Heiko Thieme unter http://www.audio-cd.at/people - Hans Lang am 11.11. PIR: http://www.audio-cd.at/private-investor-relations - kapitalmarkt-stimme.at daily voice Playlist auf spotify: http://www.kapitalmarkt-stimme.at/spotify - Stockpicking Österreich: https://www.wikifolio.com/de/at/w/wfdrastil1? - beim Aktientag 2026 präsentieren (20 Slots, 11 frei): Strabag, Porr, Palfinger, Frequentis, FACC, VIG, Polytec, Semperit, UBM. ATX aktuell: https://www.wienerborse.at/indizes/aktuelle-indexwerte/preise-mitglieder/??ISIN=AT0000999982&ID_NOTATION=92866&cHash=49b7ab71e783b5ef2864ad3c8a5cdbc1 Die täglichen Folgen der Wiener Börse Party (Co-verantwortlich Script: Christine Petzwinkler) im Q4/2025 sind präsentiert von der Börse Frankfurt / Xetra https://www.boerse-frankfurt.de/xetraplus . Infos zum Jingle: https://audio-cd.at/page/podcast/7326 Risikohinweis: Die hier veröffentlichten Gedanken sind weder als Empfehlung noch als ein Angebot oder eine Aufforderung zum An- oder Verkauf von Finanzinstrumenten zu verstehen und sollen auch nicht so verstanden werden. Sie stellen lediglich die persönliche Meinung der Podcastmacher dar. Der Handel mit Finanzprodukten unterliegt einem Risiko. Sie können Ihr eingesetztes Kapital verlieren. Und: Bewertungen bei Apple (oder auch Spotify) machen mir Freude: http://www.audio-cd.at/spotify http://www.audio-cd.at/apple Du möchtest deine Werbung in diesem und vielen anderen Podcasts schalten? Kein Problem!Für deinen Zugang zu zielgerichteter Podcast-Werbung, klicke hier.Audiomarktplatz.de - Geschichten, die bleiben - überall und jederzeit! 2732 full no Christian Drastil Comm. (Agentur für Investor Relations und Podcasts)
339: Wenn du beginnst, dich mit dir selbst zu beschäftigen, wirklich hinzusehen, hinzufühlen, dich zu öffnen und Verantwortung für dein Inneres zu übernehmen – dann verstehen das nicht alle. Vor allem nicht die, die dich aus einer alten Version kennen. Manche sehen, dass du regelmäßig mit einem Coach arbeitest, dass du dich veränderst, dass du anders sprichst, anders fühlst, anders reagierst und sie verwechseln Begleitung mit Abhängigkeit.
DEAL: If you're looking for custom socks for your company, event, or sports team, go to hippyfeet.com, fill out the custom inquiry form, and mention the LABEL KING podcast. Michael will give you 15% OFF your first custom order! www.hippyfeet.com
Are you feeling "off" even though you're doing everything "right"? In this solo deep-dive, Coach Debbie maps the North-to-South flow of health—from brain and vagus nerve to stomach acid, bile, liver, gut, and mitochondria—so you can see how fatigue, belly fat, restless sleep, brain fog, and hormone chaos are often communication problems, not willpower problems. You'll learn how to restore safety signals, open drainage, support bile and choline, and retrain mitochondria from defense to performance. We connect the dots with real testing—PNOĒ RMR/AMR, GI-MAP, DUTCH, Total Tox, MRT, genetics, and Nutritional Therapy Analysis—so you can stop guessing and start rebuilding your Future You™. In this episode, you'll learn: The North-to-South Map: why vagal tone, stomach acid, and bile set the stage for metabolism. Mitochondrial intelligence & the Cell Danger Response (OAT and PNOĒ clues you can measure). Drainage before detox: Phase 1–2–3 in plain English—what to do first. Bile & choline: how to make/keep bile flowing (foods, nutrients, signs of stagnation). Cholesterol & bile: why bile is your main cholesterol exit route. The Brain–Bile–Barrier Loop: how gut/BBB permeability drives neuroinflammation. Muscle as metabolic medicine: training & protein targets that signal repair. Testing, Not Guessing: how your data becomes your roadmap. Ready to see what your metabolism is really doing? Book your PNOĒ Metabolic Test + Functional Health Review: www.DebbiePotts.net Resources mentioned: PNOĒ RMR & AMR testing GI-MAP stool test DUTCH hormone panel Total Tox (metals, environmental, mycotoxins) MRT food sensitivity test Genetics + Nutritional Therapy Assessment Who this is for: high-performers in midlife, peri/menopause, athletes and go-getters who feel overtrained, under-recovered, or stuck despite clean eating and supplements. Follow & connect: www.DebbiePotts.net | @coachdebbiepotts Share this episode with someone who needs a data-driven path from Metabolic Chaos® → Metabolic Harmony. Educational only. Partner with a qualified practitioner—especially if you're on medications, have gallbladder disease, significant anemia, active IBD, are pregnant, or have complex conditions.
Dr. Stacy Lindborg, President and CEO of IMUNON, has developed a DNA-based immunotherapy candidate for the treatment of ovarian cancer. This therapy works by administering the drug, which utilizes IL-12, a powerful anti-cancer cytokine, directly into the cavity where the cancer resides, thereby affecting the tumor microenvironment. Trials are showing that the drug can produce significant life extension when used in combination with standard chemotherapy. Stacy explains, "There are about 300,000 women who are newly diagnosed with advanced ovarian cancer every year, about 20,000 in the US, and the frontline standard of care hasn't seen a change in the treatment in about 25 years. So this is for newly diagnosed women. The very first treatment that they would have, which we call frontline treatment, is a platinum-based chemotherapy. So carboplatin and Paclitaxel are both administered through IV over an hour for carboplatin, about three hours for Paclitaxel. So most women go directly to chemotherapy and then surgery, and then chemotherapy. Some women will go straight to surgery and then have this chemotherapy afterwards." "Our approach is a DNA-based immunotherapy candidate that we have in Phase 3. We refer to the lead candidate as IMNN-001, and this is a non-viral nanoparticle that is administered directly into the cavity of interest. So, what we call the micro-tumor environment is the peritoneal cavity, where the cancer actually resides, and it's delivered through a catheter. And it basically has a very powerful anti-cancer fighting cytokine, IL-12, that is encoded in this immunotherapy. And it causes the cells that are within each woman's body, both cancer and non-cancer alike, to start producing activities that will help fight these complex cancer cells that exist." #IMUNON #OvarianCancer #DNABasedImmunotherapy #WomensHealth #CancerAwareness imunon.com Download the transcript here
Dr. Stacy Lindborg, President and CEO of IMUNON, has developed a DNA-based immunotherapy candidate for the treatment of ovarian cancer. This therapy works by administering the drug, which utilizes IL-12, a powerful anti-cancer cytokine, directly into the cavity where the cancer resides, thereby affecting the tumor microenvironment. Trials are showing that the drug can produce significant life extension when used in combination with standard chemotherapy. Stacy explains, "There are about 300,000 women who are newly diagnosed with advanced ovarian cancer every year, about 20,000 in the US, and the frontline standard of care hasn't seen a change in the treatment in about 25 years. So this is for newly diagnosed women. The very first treatment that they would have, which we call frontline treatment, is a platinum-based chemotherapy. So carboplatin and Paclitaxel are both administered through IV over an hour for carboplatin, about three hours for Paclitaxel. So most women go directly to chemotherapy and then surgery, and then chemotherapy. Some women will go straight to surgery and then have this chemotherapy afterwards." "Our approach is a DNA-based immunotherapy candidate that we have in Phase 3. We refer to the lead candidate as IMNN-001, and this is a non-viral nanoparticle that is administered directly into the cavity of interest. So, what we call the micro-tumor environment is the peritoneal cavity, where the cancer actually resides, and it's delivered through a catheter. And it basically has a very powerful anti-cancer fighting cytokine, IL-12, that is encoded in this immunotherapy. And it causes the cells that are within each woman's body, both cancer and non-cancer alike, to start producing activities that will help fight these complex cancer cells that exist." #IMUNON #OvarianCancer #DNABasedImmunotherapy #WomensHealth #CancerAwareness imunon.com Listen to the podcast here
Buy/Stream: https://overview.fanlink.tv/OVR118-Phase Widely acclaimed Belgian producer Phase steps forward for his Overview Music debut, the incredible ‘Blinded EP'. No stranger to heavy club orientated Drum & Bass, Phase embarks further into this territory, experimenting with new mid range led synth work, resulting in some of his most aggressive yet distinct music yet. Out 14.11 Phase Instagram → https://www.instagram.com/phasednb Facebook → https://www.facebook.com/phasednb Soundcloud → https://soundcloud.com/phasednb Overview Music Patreon → https://patreon.com/overview Facebook → https://facebook.com/overviewuk Instagram → https://instagram.com/overviewuk Soundcloud → https://soundcloud.com/overviewuk YouTube → https://youtube.com/@OverviewMusic
Bilaspur Train Accident Highlights News Updates: Overshooting red signal by passenger train likely cause, says Railway Board Barbs, bluster as rallies for Phase 1 of Bihar polls wind up Poll roll revision ph-2 begins amid protests Key Delhi air monitor went dark in peak farm fire week Amid rejig buzz, Cong high command treads carefully How Mamdani stunned New York - and what Democrats can learn from his win ‘They speak frequently': White House says Trump-Modi trade talks continue David Beckham knighted by King Charles III at Windsor Castle, England legend calls it ‘extra special' Learn more about your ad choices. Visit megaphone.fm/adchoices
In dieser Woche sprechen wir über die Therapie bei Leukämie – von der intensiven Chemotherapie über unterstützende Maßnahmen bis hin zur Stammzelltransplantation. Wir erklären dir, wie die Behandlung in Zyklen abläuft, warum Pausen so wichtig sind und welche Risiken durch das geschwächte Immunsystem entstehen. Außerdem tauchen wir tief in die Welt der Stammzelltransplantation ein: autolog vs. allogen, Chancen, Gefahren und die Rolle der Pflege in dieser sensiblen Phase. Und damit machen wir dich wieder fit für deine Prüfungen und die praktische Arbeit auf Station.
In den ersten 30 Tagen nach der Kalbung entscheidet sich, wie gesund und leistungsfähig eine Kuh bleibt – und die Ursache vieler Krankheiten liegt schon im Trockenstand. In dieser Folge spreche ich mit Anne-Marie Decker von Cowmanager darüber, wie du diese kritische Phase besser im Blick behältst – mithilfe von Daten, die zeigen, was im Stall wirklich passiert. Wir sprechen über:
In this episode of The Tree Planters Podcast, we return to St. Paul's Centre to explore Phase 2 of the Art of Reconciliation project — a stage shaped by the artists themselves as they asked, “Where are you now in your personal reconciliation process?” This round, created between 2015 and 2018, brought together Indigenous and non-Indigenous artists whose works reflect on truth, listening, and shared responsibility. Guided by the Seven Grandfather Teachings — wisdom, love, respect, bravery, honesty, humility, and truth — the installation invites reflection on how communities grow more aware, and how reconciliation can become a living, everyday practice. Our conversation considers how these pieces, and the process behind them, deepen local understanding of reconciliation within Simcoe County and beyond.Support the show
Teagasc advisor, Tom Coll, is on this week's OviCast with some practical management tips as the breeding season draws to a close. Tom highlights the importance of ram management at this stage — from identifying repeats to dealing with injured or lame rams. We also chat about why it's a good idea to group ewes in the latter half of the breeding period and the benefits of having a spare ram available. The discussion then turns to managing ram lambs, reducing the risk of fighting post-mating, and best practices for ram care once the breeding season ends. We finish up by talking about the importance of monitoring and managing ewe condition in the lead-up to housing. For more episodes from the OviCast podcast, visit the show page at:https://www.teagasc.ie/animals/sheep/ovicast-sheep-podcast
Michaela Grönnebaum, Fotografin mit einem einzigartigen Blick für Schönheit, kämpfte lange Zeit mit ihrem eigenen Selbstbild, da sie mit einem Blutschwamm im Gesicht zur Welt kam. In diesem berührenden Interview teilt sie ihren Weg voller Mut und Herz: Wie sie ihre Leidenschaft für die Fotografie zum Beruf machte, die vermeintliche Sicherheit eines festen Jobs aufgab und trotz großer Rückschläge – bis hin zu einer depressiven Phase – ihren Weg fand. Sie erzählt von ihrer spontanen Auswanderung nach Portugal, der schrittweisen Annahme ihrer äußeren und inneren Schönheit und warum es keine Umwege im Leben gibt. Michaela inspiriert dazu, die eigene Geschichte als Stärke anzunehmen, sich selbst unperfekt und wunderschön zu zeigen und dem Ruf der eigenen Berufung zu folgen. Freue dich auf eine wundervolle Folge mit einer wundervollen Gästin.Mehr zu Michaela: Website Instagram LinkedInWorkation Online-Kurs 'Time to Shine'Mehr zu mir: Hol dir den Newsletter kostenloser Traumjob-Workshop - wie du einen Job findest, der dich wirklich erfüllt.Schema Du® Traumjob Coaching - erfolgreich & erfüllt im Job, den du liebst.Schema Du® Confidence Coaching - selbstbewusst & überzeugend - ohne dich zu verbiegen oder aufzuspielen.Schema Du® Membership - Die Membership für mehr Leichtigkeit und Selbstvertrauen im Job.Du hast Fragen, wie ich dich unterstützen kann und möchtest wissen, ob mein Coaching jetzt das richtige für dich ist? Melde dich zu einem kostenfreien Klarheitsgespräch.Oder schreib mir eine DM bei Instagram. Ich freue mich von dir zu lesen! Hier geht's übrigens zu meiner Website.
Bei der Entwicklung von Arzneimitteln geht es nicht nur um viel Geld, sondern vor allem auch um Menschenleben. Wie kann uns KI hier helfen bessere Medikamente schneller oder sicherer an den Markt zu bringen? Darüber spricht Christian Krug, der Host des Podcasts „Unf*ck Your Data“ mit Christof Layher, selbständiger IT Stratege für Life Science und Host des Chaoshacker Podcasts.Die Zulassung neuer Medikamente ist nicht nur langwierig, sondern auch sehr teuer. Um das Ganze dann noch dramatischer zu machen stehen bei im schlimmsten Fall Menschenleben auf dem Spiel oder zumindest das Wohlbefinden.Aber genau hier gibt es spannende Anwendungspotentiale für KI. Einige lassen sich dabei aus anderen Bereichen ableiten andere sind hoch spezifisch.In der Administration und Regulation geht es um Texte, Gesetze und Verordnungen, gerne auch in mehreren Sprachen. Die Anwendung von Sprachmodellen drängt sich hier ja schon fast auf. Natürlich immer mit einem etwas sorgfältigerem Blick fürs Detail, aber oft gewinnt eben der erste am Markt und da können Tage entscheiden.Aber schon in der frühesten Phase, dem Finden von potentiellen Wirkstoffen kann KI helfen. So können Modelle der Moleküle helfen gute Kandidaten zu finden. Denn 90% aller Wirkstoffzulassungen scheitern irgendwo auf dem Weg. Wenn du früher aussortierst sparst du Zeit und Geld.Und so geht es weiter durch den ganzen Lebenszyklus des Medikaments. KI Systeme können helfen die Studien gut zu gestalten, geeignete Testzentren zu finden, Tierversuche zu reduzieren oder ganz abzuschaffen und sogar die Plazebogruppe kann zum Teil simuliert werden.Was viele außerhalb der Branche nicht wissen: Jedes Arzneimittel muss ständig überwacht und überprüft werden. Gerade hier können KI System helfen die Daten zu sammeln oder erfassten. Denn auch ein Blogeintrag oder die Diskussion in online Foren kann Hinweise auf seltene Nebenwirkungen geben. Und dann natürlich direkt in der Auswertung.Aber warum ist das alles oft nicht so einfach und was muss ich dabei beachten?Die Antworten geben wir in der Folge.▬▬▬▬▬▬ Profile: ▬▬▬▬Zum LinkedIn-Profil von Christof: https://www.linkedin.com/in/christoflayher/Zum Chaoshacker Podcast: https://open.spotify.com/show/6IyYylGFei1TiPNnJtnXJw?si=0f2568c3958f439c&nd=1&dlsi=2f0394f182ab450bZum LinkedIn-Profil von Christian: https://www.linkedin.com/in/christian-krug/Christians Wonderlink: https://wonderl.ink/@christiankrugUnf*ck Your Data auf Linkedin: https://www.linkedin.com/company/unfck-your-data▬▬▬▬▬▬ Buchempfehlung: ▬▬▬▬Buchempfehlung von Christof: Projekt Lightspeed – Joe MillerAlle Empfehlungen in Melenas Bücherladen: https://gunzenhausen.buchhandlung.de/unfuckyourdata▬▬▬▬▬▬ Hier findest Du Unf*ck Your Data: ▬▬▬▬Zum Podcast auf Spotify: https://open.spotify.com/show/6Ow7ySMbgnir27etMYkpxT?si=dc0fd2b3c6454bfaZum Podcast auf iTunes:
Text us a pool question!Swimming Pool Leak Suspection refers to the initial stage of identifying and investigating potential water loss in a swimming pool system when there is reason to believe a leak may exist.In practical terms, it means a pool owner or service technician has observed indicators suggesting abnormal water loss—such as a consistently dropping water level, air bubbles in the return lines, excessive chemical use, soggy areas around the pool, or unexplained increases in water bills—but has not yet confirmed the presence or location of a leak.Leak suspection triggers diagnostic testing, including visual inspections, the bucket test (to distinguish between evaporation and leakage), pressure testing, dye testing, or electronic leak detection. It's essentially the diagnostic hypothesis phase of leak detection—where symptoms point toward a problem, but confirmation requires controlled testing and data verification. Support the showThank you so much for listening! You can find us on social media: Facebook Instagram Tik Tok Email us: talkingpools@gmail.com
Good morning from Pharma Daily: the podcast that brings you the most important developments in the pharmaceutical and biotech world. Today, we're diving into a series of transformative events reshaping the landscape of healthcare, from strategic mergers and regulatory shifts to groundbreaking advancements in drug development.Let's begin with a monumental merger that signals a shift towards more integrated healthcare solutions. The $48.7 billion acquisition of Kenvue, a consumer health spinout from Johnson & Johnson, by Kimberly-Clark illustrates the growing convergence between consumer health products and traditional pharmaceuticals. This strategic move highlights a trend towards expanding product portfolios and enhancing distribution networks, aiming to better address comprehensive patient needs. Mergers like these could redefine how healthcare products are marketed and delivered, emphasizing holistic approaches to patient care.Turning to regulatory news, the resignation of Dr. George Tidmarsh from the FDA due to controversial communications has spotlighted the ongoing challenges within regulatory oversight. This incident underscores the delicate balance regulators must maintain in ensuring transparency while safeguarding sensitive information. Such developments are crucial as they directly affect public trust in drug approval processes and the industry's ability to navigate complex regulatory landscapes.In scientific advancements, Roche is making significant progress with its drug Gazyva for autoimmune diseases. Following FDA approval for lupus-related kidney disease, promising Phase 3 trial results for systemic lupus erythematosus (SLE) are propelling Roche closer to offering new hope for patients with this chronic condition, which currently has limited effective treatments. This success underscores the potential of targeted therapies in transforming treatment paradigms for autoimmune diseases.Eli Lilly's $3 billion investment in a new manufacturing facility in the Netherlands marks a strategic effort to bolster oral medicine production globally. This expansion not only reinforces Lilly's commitment to meeting global demand but also reflects an industry-wide trend towards investing in scalable manufacturing capabilities. Such moves are critical for ensuring supply chain resilience and addressing rising healthcare needs worldwide.In legal news, Pfizer's fierce competition with Metsera over Novo Nordisk's counteroffer highlights the high stakes involved in securing promising assets within the biotech sector—a sector particularly focused on obesity treatment due to its substantial market growth potential. The outcome of this legal battle could influence future strategic partnerships and acquisitions, demonstrating the intense competition among pharmaceutical giants.Meanwhile, UniQure faces challenges as its gene therapy for Huntington's disease encounters regulatory hurdles with the FDA. Despite initial expectations as a groundbreaking treatment, this setback emphasizes the rigorous scrutiny gene therapies undergo to ensure safety and efficacy. Such hurdles highlight the complexities of advancing novel therapies through regulatory pathways.Policy developments are also reshaping drug pricing structures as evidenced by HRSA's approval of eight drugmakers' plans for a 340B rebate model pilot program. This initiative aims at optimizing pricing structures while balancing cost containment with access to essential medications for underserved populations—a critical concern in today's healthcare landscape.International collaborations continue to play a pivotal role in accelerating drug discovery and development. Neurocrine Biosciences' $880 million deal with China's TransThera Sciences exemplifies such partnerships, focusing on emerging therapeutic areas like immunology. These collaborations are vital in leveraging global expertise and resources to drive innovatSupport the show
Explaining the “Implicit Phase” (months 1–5) of dating multiple women openly, continuing FB or MLTR dynamics while postponing labels and keeping communication clean. You'll learn how to signal non-exclusivity without lying, handle the “What are we?” question gracefully, and use evidence—not proof—to avoid drama and set up a smooth transition to Phase 3.
Meditation für jeden Tag | Der Podcast von Inhale Life | Kurz geführte Mini Meditationen auf deutsch
Manchmal gibt es Tage, an denen sich alles grau anfühlt. Nichts macht so richtig Sinn, die Energie fehlt – und man weiß vielleicht gar nicht so genau, warum. Diese Meditation möchte dir in solchen Momenten eine sanfte Begleitung sein. Sie hilft dir, wieder in Kontakt mit dir selbst zu kommen, die innere Schwere ein bisschen aufzulösen – und dich daran zu erinnern, dass auch diese Phase vorbeigeht.
There are plenty strategies for hunting the rut. But the ones Canyon talks about on this Full Draw Friday are tried and true ways to put your tag on a mature buck this November. He also talks about why the bucks are doing what they're doing, and how that helps you hunt them.Ridge Hunter Products and Merchandise:Ridgehunteroutdoors.comDiscount Code: RHOPOD for 10% off everything in your orderSupport our Partners:For any info on real estate available through Midwest Farm and Land, or anything that RG Outdoors has, contact Rodney Hawkins 618-925-3153.Check out Raks Big Game Supplements for all your mineral and protein needs! Go to Raksmineral.com and use code FULLDRAW for 15% off your entire order!Submit questions or comments to: Ridgehunteroutdoors@gmail.comFind us on Social:YouTube: https://www.youtube.com/channel/UC50IZ_HE2pnMBjRyPpmgvMg Facebook: https://www.facebook.com/RidgeHunterOutdoors Instagram: https://www.instagram.com/ridgehunteroutdoors/ Twitter: https://twitter.com/RidgeHunterOD
Phase V of The Change Leader's Roadmap: Analyze the Impact, takes a deep dive into the actual magnitude of change work that will be triggered by implementing the Desired State design determined in Phase IV. It compares all relevant aspects of the current state—organizational, behavioral, cultural and mindset—with the requirements of the Desired State. The questions and impacts needing further attention are identified, grouped, assigned, and assessed so they can be prioritized, resolved and planned for in the next phase. This work is essential to generate the Implementation Master Plan and identify a realistic timeline and resources.Hosted by Ausha. See ausha.co/privacy-policy for more information.
Following a fruitful European Society of Medical Oncology (ESMO) Congress 2025 for gastrointestinal malignancies, CancerNetwork® organized an X Spaces discussion hosted by 3 experts. They were Nicholas J. Hornstein, MD, an assistant professor at the Donald and Barbara Zucker School of Medicine of Hofstra University and Northwell Health; Timothy Brown, MD, an assistant professor in the Department of Internal Medicine and the associate program director of the Hematology & Oncology Fellowship at UT Southwestern Medical Center; and Udhayvir S. Grewal, MD, an assistant professor in the Department of Hematology and Medical Oncology at Emory University School of Medicine. Each doctor focused on a specific disease type, highlighting the most important abstracts in colorectal cancer, pancreatic neuroendocrine tumors (NETs), and upper gastrointestinal cancers. The Phase 3 MATTERHORN Trial (NCT04592913) Results from MATTERHORN demonstrated that adding durvalumab (Imfinzi) to 5-fluorouracil, leucovorin (folinic acid), oxaliplatin, and docetaxel (FLOT) improved overall survival (OS) compared with FLOT plus placebo in patients with resectable gastric/gastroesophageal junction (GEJ) adenocarcinoma, regardless of pathological status.1 In the intention-to-treat population, the median OS was not reached in either arm, and the hazard ratio (HR) was 0.78 (95% CI, 0.63-0.96; P = .021). Notably, the improvement was observed regardless of PD-L1 status; in patients with PD-L1–positive disease, the HR was 0.79 (95% CI, 0.63-0.99), and in patients with PD-L1–negative disease, the HR was 0.79 (95% CI, 0.41-1.50). “This, I believe, will seal durvalumab plus FLOT as the standard of care for resectable [gastric/GEJ] cancers,” said Brown. The Observational ASPEN Study (NCT03084770) The ASPEN study showed that active surveillance was a safe approach for patients with low-grade, asymptomatic, nonfunctioning pancreatic neuroendocrine tumors (NETs) fewer than 2 centimeters in size.2 Of the 1000 patients enrolled in the trial, 20 patients died, of whom 18 underwent active surveillance and 2 underwent surgery. Nineteen of the deaths were unrelated to pancreatic NETs; 1 death in the surgery arm was related to a pancreatic NET. After surgery, 5 patients had disease relapse or progression. With a median follow-up of 42 months (IQR, 25-60), the OS analysis showed a P value of 0.530. “This really settles the debate on whether or not to surgically operate on patients with a [pancreatic NET] size of [fewer] than 2 centimeters and shows that active surveillance is a safe option for these patients with pancreatic NETs [fewer] than 2 centimeters in size and non-functional NETs,” said Grewal. Data From the Phase 2/3 FOxTROT (NCT00647530) and Phase 2 NICHE-2 (NCT03026140) Trials Neoadjuvant nivolumab (Opdivo) plus ipilimumab (Yervoy) achieved a clinically meaningful and statistically significant improvement in long-term outcomes, including responses and survival, compared with chemotherapy strategies in patients with mismatch repair deficient (dMMR) or microsatellite instability–high (MSI-H) locally advanced colon cancer.3 In NICHE-2, neoadjuvant nivolumab plus ipilimumab achieved a 3-year disease-free survival (DFS) rate of 100% compared with 80% (95% CI, 73%-85%) with all chemotherapy strategies in FOxTROT (P
Das Wichtigste am Montag: In Berlin wird ein Zwischenbericht zur Suche nach einem Endlager für hochradiokativen Atommüll vorgestellt, in Istanbul diskutieren Außenminister aus Nahost über die zweite Phase des Gaza-Friedensplans – und in den Niederlanden wird das Briefwahlergebnis verkündet.
Du kennst es bestimmt: du bist so verliebt und denkst “endlich hab' ich den oder die Richtige gefunden!” Nur um ein paar Wochen/Monate später zu merken, dass dich dieser wundervolle Mensch ganz schön triggert. Warum es so kommen muss, ein neuer Partner nicht die Lösung ist und wie du aus der Dynamik aussteigst, in dieser neuen Folge. In dieser Podcastfolge erfährst du: • welche Phasen alle Liebesbeziehungen durchlaufen • wie du romatische Phase entsteht und warum sie enden muss • wie du deine Beziehung aus dem Power Struggle in eine bewusste Beziehung führst Du möchtest tief in das Thema Partnerschaft eintauchen und von uns lernen? Dann lerne unser großes 90-tägiges Beziehungsprogramm ,Relationships with Ease' kennen. Hier findest du mehr Infos: https://www.annalena-reimo.com/relationships-with-ease Du möchtest den Short-Cut & direkt starten? Trage dich ein für ein kostenfreies Erstgespräch für eine 1:1 Coaching Begleitung: https://www.annalena-reimo.com/erstgespraech Dir hat die Folge gefallen? Dann teile sie gerne mit Menschen, die sie auch unbedingt hören müssen, abonniere den Podcast, um keine Folge mehr zu verpassen und hinterlasse uns eine Bewertung. Damit unterstützt du uns dabei, noch mehr großartige Menschen da draußen zu erreichen und zu ihrem NEXT LEVEL in ihrer Beziehung und ihrem Leben zu begleiten. Von Herzen DANKE! Mehr zu uns: • Homepage: https://www.annalena-reimo.com • Instagram: https://www.instagram.com/annalena.reimo • YouTube: https://www.youtube.com/c/annalena-reimo • Facebook: https://www.facebook.com/annalenareimo Alles Liebe, Annalena & Reimo
John 11:1-7,Now a certain man was ill, Lazarus of Bethany, the village of Mary and her sister Martha. 2 It was Mary who anointed the Lord with ointment and wiped his feet with her hair, whose brother Lazarus was ill. 3 So the sisters sent to him, saying, “Lord, he whom you love is ill.” 4 But when Jesus heard it he said, “This illness does not lead to death. It is for the glory of God, so that the Son of God may be glorified through it.”5 Now Jesus loved Martha and her sister and Lazarus. 6 So, when he heard that Lazarus was ill, he stayed two days longer in the place where he was. 7 Then after this he said to the disciples, “Let us go to Judea again.”With John 10 behind us, we enter now into a new phase of Jesus' ministry. Phase one opened with John the Baptist baptizing in the wilderness east of the Jordan. That was back in chapter one. Nine chapters later — following a variety of Jesus' miracles and Jesus' teachings, crowds coming and crowds going, Pharisees questioning and Pharisees condemning — we ended up back in the very same place it all began. John 10:40,“Jesus went away again across the Jordan to the place where John had been baptizing at first.” So, phase one has come full circle. Jesus' public ministry has all about concluded. And at this point, life actually looks pretty good for Jesus. John 10:41 says of Jesus, having returned to this region of the Jordan,“And many came to him [so, he's got the crowds]. And many said, “John did no sign, but everything that John said about this man was true [he's got public testimony]. And many believed in him there [he's got ministry success].”Sounds pretty good, right? Jesus is at last away from the tension and death-threats he'd been experiencing in Jerusalem. He's not having to walk mile-after-mile from town-to-town like he did in Galilee. He's east of the Jordan. He's got his disciples all round him. He's got the crowds coming to him and believing him. Life, right now, looks pretty good for Jesus. Then, like a fly in the ointment, John 11 begins,“Now a certain man was ill, Lazarus of Bethany, the village of Mary and her sister Martha.”Hmm, now what might that mean for Jesus? What might that news of one, relatively unimportant person's illness, mean for Jesus — especially in light of crowd-sized, relatively comfortable success? In this morning's text, we're going to see Jesus' response to this one, relatively unimportant person's illness. It's a response that's going to give us a window into three truths about the heart and character of Jesus:Jesus personally loves his people.Jesus prizes his Father's glory.Jesus pursues our very best.Let's pray …. 1. Jesus Personally Loves His PeopleJesus personally loves his people. Let's begin at John 11:1.“Now a certain man was ill, Lazarus of Bethany, the village of Mary and her sister Martha. [and then there's little this parenthesis…] It was Mary who anointed the Lord with ointment and wiped his feet with her hair, whose brother Lazarus was ill.”Now, this is foreshadowing. We've not read about this event just yet, but we will see it in chapter 12. For now, John's just flagging it — saying, “Hey, keep your eye on this family; make note of the connection here: Lazarus, Mary, Martha — they're siblings. Siblings who are going to have some significant interaction with Jesus in the next few days.”So, imagine it with me, Mary and Martha are in their home. Their brother Lazarus gets sick. And sickness is a dangerous thing in the ancient world. Not many options for medicine or doctors. Then, the sickness worsens. Things are beginning to look bad. The sisters think: Let's send for Jesus. Verse 3:“So the sisters sent to him, saying, ‘Lord, he whom you love is ill.'” Again, remember where Jesus was at this time. This message concerning Lazarus gets delivered to Jesus at a time when he's living in relative security. In it comes — the message that Lazarus of Bethany is ill. And, you just gotta think, I mean — “Lazarus, I'm sorry, but the timing's just not great right now. Your location, a bit too close for comfort to Jerusalem. And you're just one person compared to the many who are coming my way.”And, look, let's get real, I mean: how many people had Jesus' interacted with throughout his three years of public ministry? We know he fed the 4,000. We know he fed the 5,000. We know, at times, he had crowds so large he had to get into a boat so as to not be trampled by them. Even now, he's got waves of people coming toward him. You think he even remembers Lazarus? You think he really has capacity — with all the other things he's doing and all the other people he's caring for — to show concern for this one single, relatively unimportant individual?Well, the sisters sure seem to think so. Just look how they describe their brother to Jesus. The message is not, “Lord, he whom you appreciate; he whom you might remember; nor is it even he who loves you. The message from the sisters is, “Lord, he whom you love is ill.”Now, why is it that these sisters believe Jesus loves their brother? Well, I imagine Jesus told them he did. And Jesus showed them he did. That his previous posture toward Lazarus had not been one of cold, detached indifference. Like, when Jesus had been around Lazarus, he had not been checking his watch, or rolling his eyes, or day-dreaming about all the other places he'd rather be. No, no, no, Jesus loved Lazarus and it showed. The sisters knew, Jesus loves our brother. And this, is stunning. Earlier in John — 3:16 — we read that God loves the world. It's an amazing truth, yes? It's also a broad truth — gloriously broad, but broad nonetheless. After all, you've gotta zoom out quite a bit to see the whole world, right? And when you zoom out, what happens to you? What happens to the individual? They fade into the crowd. That is, when humans who are merely humans look at the world. But see, here is where God is different. Here is where Jesus, the Son of God, is different. Jesus has capacity, boundless capacity, to love the world and love individuals within the world. It is not an either/or for Jesus. “Either, I'm a big, distant God. Or, I'm a small, personally involved God.” No, no, no — God loves the world, and God loves his people — collectively, and individually. Calls them by name, counts the number of hairs upon their heads, knows the exact number of days he's given them. Jesus did not love Lazarus generally. Jesus knew Lazarus: Knew what he looked like, knew what he sounded like, knew — even as we'll see in a moment — the details concerning Lazarus' sickness and where it was headed. Jesus knew Lazarus — and his sisters by the way (see that in verse 5) — he knew them personally, and loved them personally. How would you, this morning, describe Jesus' love for you? Do you believe Jesus knows what you look like? What you sound like? What difficulties and sorrows have befallen you? Do you believe that if you, like Lazarus, were to get sick. Get hurt. Need help, and send for Jesus — Do you think Jesus would need a reminder of who you were? Need to jog his memory: “now how exactly is it again that I know this person?” Do you think he'd not be the first to pause the messenger: “wait, wait, wait — I don't need you to describe who she is. I don't need you to tell me who he is. I love that man. I love that woman. And I have since before the foundation of the world.” Look, Jesus' just got done telling us:John 10:14,“I am the good shepherd. I know my own.”John 10:27,“My sheep hear my voice, and I know them.” Jesus, my brothers and sisters, personally loves his people. That's the first truth about Jesus: Jesus personally loves his people. 2. Jesus Prizes His Father's GloryVerse 4:“But when Jesus heard it [that is, heard that Lazarus was sick] he said, ‘This illness does not lead to death. It is for the glory of God, so that the Son of God may be glorified through it.'”Now, we've got to ask: what, exactly, is Jesus getting at here. He says, “This illness does not lead to death.” But, I mean, doesn't it? Lazarus does, in fact, end up dying, right? I mean, he'll be four days in the tomb by the time Jesus finally arrives in Bethany. Four days without a heart beating. Four days without lungs breathing. Four days without any activity in the brain. He dies. And so, when Jesus says, “This illness does not lead to death.” What's he mean? I think there's layers of meaning here, but at the top, is purpose. That is, the purpose of the illness is not death. Yes, his illness will lead to his death, but its purpose is “for the glory of God.”And now, we've seen something like this before in John already. Just two chapters earlier, John 9, the disciples ask Jesus concerning the blind man, “Who sinned, this man or his parents, that he was born blind?” Jesus answered in terms of purpose: “It was not that this man sinned, or his parents, but that the works of God might be displayed in him.”There's purpose to the suffering. Purpose to the plight. That blind man was not blind for nothing. Lazarus is not sick for nothing. The purpose of God is to display the glory of God through the blindness and the illness. So, that's shared ground between John 9 and John 11. Now, what's relatively new here, not only in John 11 but the book of John as a whole, is the complementary dynamic between the Father's glory and the Son's. And, you gotta see this with me. This is an amazing claim being made here by Jesus in verse 4. So, look there with me. Verse 4: Jesus does not just say: “It is for the glory of God.” But, “It is for the glory of God, so that the Son of God may be glorified through it.” The Son is clearly after the Father's glory, yes? And, the way that glory is revealed to the world is through him, through the Son. They are respective, in other words, function in tandem. Jesus magnifies the Father through his obedience to him. The Father magnifies Jesus through his honoring of him. Jesus goes to the cross, it glorifies the Father. The Father raises him from the grave to restore honor to the Son. The Father and the Son's relationship is one of mutual glorification.Now, remember, all of this is under the banner of “Jesus prizes his Father's glory.” Point one: Jesus personally loves his people. Point two: Jesus prizes his Father's Glory. And the fact that the second point follows the first is so important, so helpful, especially in our particular cultural moment. For we live in an age where it is common not just for the world, but for churches, ministries, writers of worship lyrics, to tout a view of Jesus that suggests we are supreme in his mind. We rank highest in his sight. We (and I want to say this as graciously as I can) are almost like God to him. The message is that he needs us, he's incomplete without us, he is unhappy unless we're with him — it's like we're god to Jesus.Now, look, church, Jesus loves us. Point one — he loves you personally. But he does not worship you or me. Jesus loves us, but he does not need us. Jesus loves us, and he's for us, but he's not only for us, as if we are the only thing in all of life that matters to Jesus. Listen, Jesus prizes his Father's glory, and does so supremely. His highest allegiance is not to us, but to his Father. And that is really, really good news, because if that were not true of Jesus, then he'd be a sinner in need of a Savior just like you and me. Jesus prizes his Father's glory, and, he loves us personally.So, Jesus personally loves his people. And Jesus prizes his Father's glory. Finally: Jesus pursues our very best.3. Jesus Pursues Our Very BestVerse 5:“Now Jesus loved Martha and her sister and Lazarus. So, when he heard that Lazarus was ill, he stayed two days longer in the place where he was.”Read that again. When he heard that Lazarus was ill — he'd become aware of the need, aware of Lazarus' suffering, aware of the sisters' anxiety concerning their brother, and then, he stayed two days longer in the place where he was.It's a contradiction, isn't it? Seems it should either read, “Since Jesus hadn't yet heard that Lazarus was ill, he stayed two days longer.” Or, “When he heard that Lazarus was ill, he decided not to stay two days longer, but to race on over to Bethany instead.” But, as it is, the text reads: So, when he heard that Lazarus was ill, he stayed two days longer in the place where he was.” What do we make of this? What's Jesus after? Well, that's precisely the point. What Jesus is after is our very best. See it with me. Watch how this thing unfolds. Verse 7:Then after this he said to the disciples, “Let us go to Judea again. The disciples said to him, “Rabbi, the Jews were just now seeking to stone you, and are you going there again?Simple question, right? Jesus, you mean to go right back to where there's a mob seeking to kill you? It's a simple question. But watch Jesus' answer. Verse 9:“Are there not twelve hours in the day? If anyone walks in the day, he does not stumble, because he sees the light of this world.” Who's the subject of that answer? Jesus had been the subject of the disciples' question, right? “Rabbi, the Jews were just now seeking to stone you, and are you going there again?” Who's the subject of Jesus' answer? Who is it that's walking in the day, seeing the light of the world (not being, but seeing the light of the world), and thereby not stumbling? It's not Jesus. Jesus is the light of the world. Who is it that's seeing the light of the world? It's the disciples. Jesus' answer is about them. Jesus is after what's best for them. And he knows they're frightened by the mob in Judea. Frightened by the danger awaiting them there. And so, he's telling them, “So long as you follow me there, keep me, the light of the world, in front of you, you're not going to stumble.” He's saying, “stay with me. You've got nothing to fear so long as you stay with me.” And now here's the warning. Verse 10:“But if anyone walks in the night, he stumbles, because the light is not in him.”This is the alternative for the disciples. Rather than love the light, and follow Jesus into Judea, they could love the world instead. They could remain in the comfort and safety offered them east of the Jordan. But since Jesus would then be gone, so too would the light. And there, cloaked in darkness, that's when their stumbling would occur. Those are the two options on the table: Light with Jesus as they head into danger. Or comfort without Jesus as they stumble in the dark. And Thomas is the first to get it. Verse 16, skip down there with me for a moment. Verse 16:“So Thomas, called the Twin, said to his fellow disciples, ‘Let us also go, that we may die with him.'”Thomas gets it. He gets it. “Brothers, it is better, better to go with Jesus to our deaths than live here in the dark. Let us go with him, lest we stumble.”Jesus is after our best, brothers and sisters. Not our convenience, not our safety, but our best. And he's willing to delay the miracle, willing to allow Lazarus to die, willing to have sorrow fill the hearts of Mary and Martha. He's willing to bring his disciples away from comfort east of the Jordan. He's willing to lead them right on into the danger of Judea.He's willing to do all this because he does not simply want what's good for Mary, Martha, and his disciples. But he wants what's very best. And what's very best is awaiting them in Judea — waiting for them at the tomb of Lazarus. Verse 14: “Then Jesus told them plainly, Lazarus has died, and for your sake I am glad that I was not there, so that you may believe.” Jesus could have gone to Lazarus sooner. Had he, he would have kept Lazarus from dying. Would've healed him. Would've restored him back to full health. And, oh, how glad that would have made the disciples. How relieved that would have made Lazarus' sisters. But it would have been a gladness and relief with a cost. Their reception of that good gift from Jesus would've meant their missing out on the greatest gift. And Jesus would not have that. Jesus aims to give us what's not merely good, but best — the gift of faith in him. “…for your sake I am glad that I was not there, so that you may believe.” What if suffering was a necessary ingredient for you to maintain your faith in Jesus? Discomfort? Loss and pain? What if, in order to keep you, Jesus needed to delay his help, let the bad news come, allow the tears to fall, and the sorrow to descend, and even stay for days?Could you trust in such a moment:“Jesus is after my best?”“Jesus is giving me what I most need?”“Jesus is taking care of me?”How do we hold onto our trust in Jesus when he's yet to stop the sorrow?We follow him.We follow him from the Jordan, to Bethany, to Judea, to Jerusalem, and up the hill of Golgotha to see him there hanging suffering there for you and for me. Can we trust the man upon the cross? Can we trust the man with scars in his hands? Can we trust the shepherd who lays down his life for the sheep. Jesus died to give us his very best. The TableNow, what leads us to the table this morning, is that death which Jesus willingly went toward, that he might purchase for you and for me a seat at his table. Forgiven by him, washed pure by his blood, restored to fellowship — this table is a foretaste of our future — sitting down at the table of fellowship with Jesus forever.
Der aktuelle Kinofilm "Deliver Me From Nowhere" zeigt Bruce Springsteen in einer entscheidenden Phase seiner Karriere. Musikradio360 liefert die musikalische Begleitung zum Film.
Today on Truth in Politics and Culture President Trump's Asian tour nets investment deals for the U.S. and trade agreements designed to blunt the impact of China's stranglehold on rate earth minerals, His meeting with President Xi garners mixed results. The government shutdown enters a critical phase, Erica Trump leads a Turning Point Rally at Ole Miss, VP Vance takes questions..
We're joined by Gatieh Nacario and Anna Caldwell, founders of the Kultura de Filipino Dance Company — a passionate, independent Filipino cultural dance company in Spokane dedicated to preserving and showcasing the beauty of their heritage through authentic performances. More than just a dance group, Kultura de Filipino is committed to artistic excellence, cultural education, and the personal growth of their dancers. Their performances celebrate the rich traditions of the Philippines through movement, storytelling, and traditional attire. Their dances include: Phase 1 - Dances of the Cordillera Region; Takiling, Ragragsakan, Salip and Uya-uy Phase 2 - Spanish-influence Dances; Jota Quirino, Sinakiki, Polkabal, Miligoy, Sinulog Phase 3 - Exotic Mindanao Dances; Pig-apir, Panghalay, Kapa Malong Malong, Sagayan, Dugso Phase 4 - Palawan and the Visayas Dances: Karatong, Kuradang, Itik-Itik Sibonga, Tinikling Their next performance is scheduled for Saturday, November 8 at the Spokane Folk Festival at Spokane Community College. For exact times and other performances visit spokanefolkfestival.org. To learn more about Kultura de Filipino Dance Company, visit kulturadefilipinodc.com or find them on Facebook or YouTube @KulturadeFilipinoDanceCompany.
Welcome to the NeurologyLive® Mind Moments® podcast. Tune in to hear leaders in neurology sound off on topics that impact your clinical practice. Following the 2025 Alzheimer's Association International Conference (AAIC), Rebecca Edelmayer, PhD, outlines the Alzheimer's Association's first clinical practice guidelines for using blood-based biomarkers (BBMs) in the diagnostic workup of suspected Alzheimer's disease within specialized care. She explains the guideline mission, how tests were evaluated for accuracy, and when BBMs should serve as triage versus confirmatory tools relative to CSF and PET. Edelmayer details current scope limits (cognitively impaired patients in specialty settings), cautions against overextending to primary care or unimpaired populations, and previews the education roll-out—executive summaries, micro-learning modules, and shared decision-making resources. She closes with research priorities: stronger peer-reviewed reporting, broader validation across diverse populations and settings, and building an equitable pathway that leverages BBMs to speed accurate diagnosis and treatment access. Looking for more Alzheimer & dementia discussion? Check out the NeurologyLive® Alzheimer & dementia clinical focus page. Episode Breakdown: 1:05 – Understanding the purpose and mission behind new blood-based biomarker guidelines 2:05 – Key recommendations and defining triage vs confirmatory blood-based biomarker use 3:15 – Clinical precautions and where blood-based biomarkers are appropriate today 5:30 – Neurology News Minute 7:45 – Educating clinicians on implementing BBMs in specialty care 10:15 – Research priorities to strengthen evidence and ensure equity The stories featured in this week's Neurology News Minute, which will give you quick updates on the following developments in neurology, are further detailed here: FDA Accepts New Drug Application for Tau PET Imaging Agent MK-6240 in Alzheimer Disease B-Cell Modulator Obexelimab Shows Pronounced Relapse Reduction in Phase 2 MoonStone Trial Subcutaneous Efgartigimod Shows Efficacy in Phase 2 ALKIVIA, Phase 3 ADAPT SERON Trials Thanks for listening to the NeurologyLive® Mind Moments® podcast. To support the show, be sure to rate, review, and subscribe wherever you listen to podcasts. For more neurology news and expert-driven content, visit neurologylive.com.
New Renter's rights - YouTube payout - PS5 goes flat - Masked Trio Haunting - Stupid Motorist Law - Back to the office failure - Lock Rosie O'Donnell's kid up - Talking AVs at intersections and so much more
"Als Kasernenumnutzung bezeichnet man die kurze Phase, in der eine Kaserne plötzlich als Spaßbad genutzt wird, bevor man sie wieder in eine Kaserne zurückverwandelt." Von Uli Winters.
Originally loaded October 13th, reloaded October 31st. Jeffrey Mosher welcomes back Pavan Muzumdar, Chief Operating Officer for Automation Alley & Project DIAMOnD CEO, Troy, MI, for a Project DIAMOnD Marketplace discussion. There were several questions Jeffrey wanted to find out from Pavan in this conversation: 1. The big picture: Pavan, for those who may not be familiar, in a few sentences can you explain what Project DIAMOnD is and how it's changing the way manufacturing happens here in Michigan? 2. From network to marketplace: Automation Alley recently launched the Project DIAMOnD Marketplace. Tell us what this new peer-to-peer platform does and why it's such a major milestone for distributed manufacturing. 3. Impact so far: The Project DIAMOnD network has already completed more than 50,000 3D print jobs. What kinds of parts are being produced, and what does that volume tell us about the potential of this model? 4. Empowering small manufacturers: A big part of Project DIAMOnD's mission is giving small and medium-sized manufacturers access to digital transformation technology. How does the marketplace make it easier for those smaller companies to compete, even if they don't own a 3D printer themselves? 5. Security and collaboration: You've emphasized that the marketplace protects intellectual property while enabling collaboration across hundreds of Michigan manufacturers. How does that balance work in practice? 6. Michigan's leadership role: Governor Whitmer and multiple county executives have endorsed Project DIAMOnD's statewide expansion. Why is Michigan uniquely positioned to lead the country in distributed manufacturing? 7. Call to action – getting involved: For the businesses listening, whether they want to have parts printed or join the network – how can they get involved with the Project DIAMOnD Marketplace, and what kind of opportunities does it open up for them? Automation Alley's Project DIAMOnD Launches Peer-to-Peer Marketplace for Distributed 3D Printing The marketplace builds on the success of 50,000+ 3D print jobs, showcasing the power of distributed manufacturing in Michigan TROY, Mich. – Sept. 25, 2025 – Project DIAMOnD, the nation's largest distributed 3D printing network led by Automation Alley and funded by Oakland County, has launched its new additive manufacturing marketplace – a secure, peer-to-peer platform where companies can submit 3D printing jobs at scale, and participating small manufacturers across Michigan can fulfill those jobs collaboratively. How it works: Companies that want to print at scale via the Project DIAMOnD Marketplace can reach out to contact@projectdiamond.org. Manufacturers interested in joining the network to receive a free 3D printer and training can apply through the “Join” form at www.projectdiamond.org. The marketplace is designed to protect the intellectual property of designers while giving them access to the full power of the distributed network. Jobs can be produced at higher volumes and faster speeds without requiring companies to purchase their own equipment. In fact, designers don't need to own a 3D printer at all to benefit from the network. They can simply submit their designs and have them securely manufactured at scale by participating Project DIAMOnD members. About Project DIAMOnD Project DIAMOnD (Distributed Independent and Agile Manufacturing on Demand) is creating the nation's largest connected 3D printing network, enabling small and medium-sized manufacturers and tech companies to access Industry 4.0 tools, diversify production capabilities, and respond rapidly to market demands. Funded by Oakland County in Phase 2 and powered by Automation Alley, the program provides participating businesses with grant-funded 3D printers, training, and access to a secure digital marketplace for on-demand production.
If you've ever wondered why healing can feel so hard—why it sometimes feels like one step forward and two steps back—you're not alone.For a long time, I thought I could heal by reading enough books, journaling more, or simply “being strong.” I believed that if I just worked hard enough on myself, I could finally move on from the past.But the truth is… you cannot heal alone. None of us can.Healing is not a straight line—it's a journey that unfolds in six essential phases.Each one asks something different of us: courage, surrender, curiosity, community, embodiment, and eventually, reinvention.And when we begin to see where we are in that journey, everything starts to make sense.In this week's episode of Heal Your Relationships, I'm walking you through:What each of these six phases looks likeWhy we get “stuck” in certain stages (and how to move through them)Why true healing requires community and belongingHow to make your healing journey a priority—without suffering through itThese six phases changed the way I see my own past, my relationships, and even my purpose—and I hope they'll do the same for you.Timestamps:0:00 Why healing feels so hard — and why you can't do it alone04:44 Phase 1: The emotionally reactive stage (and the moment that sparks change)07:28 Phase 2: Gathering information — why learning is only the beginning09:46 Phase 3: Finding community and belonging — the real key to lasting change14:04 Phase 4: Embodied healing — when your nervous system finally feels safe15:32 Phase 5: Practicing your true self in real life17:19 Phase 6: Reinvention — living as your healed, whole self19:22 Reflection prompts to help you see where you are in your own healing journeyOh—and if you have something you're navigating and would love my take on it... You can submit a question or situation for a future episode right here (totally anonymous!): Submit your questionP.S. Love the podcast? Reviews help us spread these life-changing tools far and wide. If you leave a 5-star review and submit a screenshot here, I'll send you my Rapid Relationship Repair mini-course—a short but powerful set of tools to reduce conflict and improve connection immediately.FREE tools:Get FREE access to my ‘Conflict Cure' mini-course, plus weekly relationship tools delivered straight to your inbox —> https://bit.ly/RelationalIQ-NewsletterNeed more customized support? Apply for a Relationship Breakthrough Call with Dr. Kavetha Sun —> https://go.oncehub.com/BreakthroughCallwithDrKavethaSun
Tara breaks down the explosive revelations from the Arctic Frost documents, exposing what she calls a “Soviet-style” surveillance campaign against the Republican Party. From Donald Trump's inner circle to every PAC, vendor, and donor, the FBI allegedly monitored phone calls, emails, bank accounts, and digital communications, all under the guise of investigation. Tara walks through the scope of the operation, the key figures involved, and the chilling implications for political freedom and party infrastructure in America. When helping Trump became a felony, no one in the Republican ecosystem was safe. In this episode, Tara examines the scope of the FBI's surveillance operation detailed in the Arctic Frost documents. She explains how every key figure in Donald Trump's 2016 and 2020 campaigns—including managers, PACs, vendors, and donors—was allegedly monitored through bank records, phone calls, emails, and websites. The surveillance reportedly expanded as campaign leadership changed from Brad Parscale to Bill Stepien, encompassing 400+ individuals and 163 organizations. Tara exposes the federal offices and agents she identifies as central to the operation, warns of the ongoing risks these officials pose, and frames the situation as a broader threat to political freedom, privacy, and the integrity of the Republican Party.
Welcome back for part 2 of our 4-part series on all things capital campaigns! Last week, Andrew and Rhen explored feasibility studies. This week, they're tackling the critical preparation phase—that crucial period between your feasibility study and your first campaign ask. As Andrew emphasizes throughout this episode, the preparation phase is about winning the game on paper. This is when your organization strategizes, prepares, and researches. Andrew and Rhen walk through every strategic and administrative thing that needs to happen before you make your first public campaign ask. Skip this phase, and you risk missing critical details, approaching donors unprepared, or worse! Like the feasibility study, this phase is an investment in your long-term success. Don't shortcut it—your campaign depends on getting this right.To access Petrus's campaign preparation guide that Rhen mentions in the episode, please click HERE.
Follow the Mister Benfica Podcast Channel on https://episodes.fm/1463340370Then select your favor podcasting platform!The Mister Benfica Podcast Channel and PTB Media Network present this fourth season of a spin-off Podcast taking you to small and medium sized towns and cities of Portugal each week with a rapid paced recap of the action in Portugal's third division. Liga3 em Inglês will keep Benfica Nation up to date with clubs big or small from our different hometowns and regions as they fight for the dream of promotion and against the nightmare of relegation. Jump in and come for a ride around the Liga 3 with the Mister @MikeAgostinho#Liga3 #PuroFutebolFollow the show on the platforms below:Twitter Instagram Facebook Apple Podcasts Spotify PodbeaniHeartRadio Amazon Music/AudibleFor more content check out www.parkingthebusmedia.comwww.misterbenfica.com
With all the democrat fixation on the Trump Ballroom being built, one democrat stands out above them all and is calling for something so crazy.... we hope it actually happens. The Ballroom Blitz appears doomed to backfire. At the same time, pride in America for democrat voters is at a 25 year low. Sounds like a win to me. Changes in some of our biggest cities are happening at the top of ICE. We have the deets on how the Border Patrol will now influence a change in procedure for mass deportations and Phase 2. Trump scores more deals in Asia as he gets ready to meet with Xi of China. The Chiefs have one stat this year that stands out above all others. A new defensive tackle signed by KC is very familiar to all of us. The Colts new female owner is changing the game on how to run a team... and she's got the top team in the AFC all of the sudden. KU's Darryn Peterson sits in an exhibition win, Toronto ties the World Series at two games a piece and our Final Final is a numbers game.
Guy Turner, Managing Director of Carbon Markets at MSCI and ICE's Gordon Bennett discuss the pricing dynamics around CORSIA-eligible credits for Phase 1 and look ahead to pricing by 2035.
In this episode of the Optimal Body Podcast, Dr. Jen and Dr. Dom, both Doctors of Physical Therapy, discuss the sacroiliac joint (SI Joint), addressing common concerns about clicking, popping, and pain—especially during pregnancy and postpartum. They explain the anatomy, debunk myths about SI joint displacement, and share practical strategies for managing discomfort, including breathwork, progressive exercise, and mobility. The hosts emphasize early intervention, movement over inactivity, and the importance of building stability through tailored exercises to help manage SI joint pain and other discomforts that can arise during pregnancy.Needed Discount:Jen trusted Needed Supplements for fertility, pregnancy, and beyond! Support men and women's health with vitamins, Omega-3, and more. Used by 6,000+ pros. Use code OPTIMAL for 20% off at checkout!Release and Recovery Challenge:Come join us starting November 3rd to Release and Recovery coming into the holiday season! We are aiming at tapping into that body and pain in ways you have likely never tried before! Grab an extra discount using code OPTIMAL10 at checkout.We think you'll love:Release and Recover ChallengeJen's InstagramDom's InstagramYouTube ChannelWhat You'll Learn:02:47 Jen shares her postpartum SI joint clunking experience and addresses a listener's question about ongoing symptoms.04:54 Discussion on whether clinicians can actually feel SI joint movement and the limitations of manual assessment.06:44 Explains causes of SI joint noises, including hormonal changes, connective tissue laxity, and hypermobility.10:12 Jen describes her postpartum experience with SI joint noises and how she managed them mentally and physically.12:55 Addresses common fears about movement with SI joint pain and emphasizes the need for progressive loading.14:50 Importance of early exercise intervention during pregnancy for SI joint pain management.16:53 Hands-on treatments provide short-term relief, but long-term improvement requires exercise and progressive overload.18:53 Instructions on using breathwork and ribcage expansion to improve core and pelvic floor coordination.20:18 Phase 1: Recommendation to start with slow, focused breathing to build pelvic and core stability.21:42 Phase 2...For full show notes and resources visit https://jen.health/podcast/432 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
Phase 2 of Trump's peace deal sputters; no order in Gaza. Tawfik Hamid joins Tony to discuss how to end Hamas's ideology of Israeli non-existence. Margot in Israel joins Tony to explain how the power vacuum in Gaza is being filled. Singapore's PM discusses the Trump Doctrine on the eve of the Trump-Xi trade meeting.
On Wednesday's Mark Levin Show, mass legal and illegal immigration without assimilation causes profound cultural and societal changes, leading to a dark period in Western societies where Marxist-Islamist ideology smothers Enlightenment values. You can see this in NYC where foreign-born voters overwhelmingly support socialist-Islamist immigrant candidate Zohran Mamdani in the mayoral race against Andrew Cuomo and Curtis Sliwa. The Democrat Party relies on Marxist-socialist beliefs for power, abandoning the American founding, Declaration, Constitution, separation of powers, and genuine elections, instead favoring unelected judges, bureaucracy and massive government spending to control the people. Later, Jeffrey Rosen calls in to discuss his new book, The Pursuit of Liberty: How Hamilton vs. Jefferson Ignited the Lasting Battle Over Power in America. Rosen explains the enduring clash between Hamilton's vision of a strong federal government and powerful executive, and Jefferson's emphasis on states' rights and individual liberties. Also, Phase two of the Gaza peace plan is highly complex involving numerous countries, governments, and figures like Trump, Kushner, Netanyahu, and Dermer, who deserve credit for their efforts. However, Hamas, a terrorist group per its 1988 charter calling for Israel's destruction via jihad, establishment of an Islamic state under Sharia, rejection of negotiations, and anti-Semitic rhetoric, refuses to disarm or surrender, instead centralizing power by torturing and killing challengers among Palestinians. The world, including the UN, universities, and Hamas supporters, remains silent on Hamas's slaughter of fellow Palestinians. Qatar's Emir condemns Israel as committing genocide in Gaza, reaffirms support for Palestine without denouncing Hamas, while Turkey's Erdogan blocks Netanyahu from a regional meeting. Israel previously surrounded and nearly destroyed Hamas but withdrew for peace and international pressure; now, hesitant Arab/Muslim nations refuse troops in Gaza, leaving Israel and the IDF to eliminate Hamas for lasting peace. Learn more about your ad choices. Visit podcastchoices.com/adchoices