Podcasts about tobramycin

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Best podcasts about tobramycin

Latest podcast episodes about tobramycin

JAMA Editors' Summary: On research in medicine, science, & clinical practice. For physicians, researchers, & clinicians.
Transcatheter Tricuspid Valve Replacement Outcomes, Tobramycin for Surgical Site Infection in Tibial Fracture, AI Drug Prescribing, and more

JAMA Editors' Summary: On research in medicine, science, & clinical practice. For physicians, researchers, & clinicians.

Play Episode Listen Later Apr 17, 2026 12:00


Editor's Summary by Linda Brubaker, MD, and Preeti Malani, MD, MSJ, Deputy Editors of JAMA, the Journal of the American Medical Association, for articles published from April 11-17, 2026.

Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Aminoglycosides Podcast – Pharmacology, Kinetics, Monitoring, and Adverse Effect

Real Life Pharmacology - Pharmacology Education for Health Care Professionals

Play Episode Listen Later Mar 26, 2026 22:20


Aminoglycosides are antibiotics used to treat serious Gram-negative infections, but they also come with important safety concerns and unique pharmacokinetic properties that healthcare professionals must understand. In this episode, we're going to break down the essential clinical pearls surrounding aminoglycosides and how pharmacists and clinicians can use them effectively while minimizing toxicity. We'll review the most common agents in this class, including Gentamicin, Tobramycin, and Amikacin, and discuss when these medications are typically used in clinical practice. From severe Gram-negative infections to synergy dosing in conditions like infective endocarditis, aminoglycosides still play a role in antimicrobial therapy. Another key focus of this episode will be the pharmacology that makes these drugs unique. Aminoglycosides demonstrate concentration-dependent killing and a post-antibiotic effect, which is why strategies like extended-interval dosing and tools such as the Hartford Nomogram are commonly used to guide therapy. We'll also cover the major adverse effects, including nephrotoxicity and ototoxicity, and highlight practical monitoring strategies to help reduce these risks. By the end of this episode, you'll have a clearer understanding of how aminoglycosides work, when they should be used, and the key dosing and monitoring principles that every clinician should know. Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE! Support The Podcast and Check Out These Amazing Resources! NAPLEX Study Materials BCPS Study Materials BCACP Study Materials BCGP Study Materials BCMTMS Study Materials Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated) Guide to Drug Food Interactions (Amazon Best Seller) Pharmacy Technician Study Guide by Meded101

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Australian Prescriber Podcast
E199 - Aminoglycosides: an update on indications, dosing and monitoring

Australian Prescriber Podcast

Play Episode Listen Later Oct 13, 2025 24:49


Dhineli Perera talks to infectious diseases physician and clinical microbiologist Carly Hughes about the latest recommendations for aminoglycoside use in Australia. They discuss indications for parenteral aminoglycosides, drug selection, dosing and therapeutic drug monitoring. Read the full article by Carly and her co-authors in Australian Prescriber.

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ER-Rx: An ER + ICU Podcast
Episode 80- One-time aminoglycosides for cystitis

ER-Rx: An ER + ICU Podcast

Play Episode Listen Later Oct 20, 2022 6:24 Transcription Available


Let's revive an old practice that may one day help you treat uncomplicated cystitis without having to admit your patient to the hospital Click HERE to leave a review of the podcast!Subscribe HERE!References:All references for Episode 80 are found on my Read by QxMD collectionDisclaimer: The information contained within the  ER-Rx podcast episodes, errxpodcast.com, and the @errxpodcast Instagram page is for informational/ educational purposes only, is not meant to replace professional medical judgement, and does not constitute a provider-patient relationship between you and the authors. Information contained herein may be accidentally inaccurate, incomplete, or outdated, and users are to use caution,  seek medical advice from a licensed physician, and consult available resources prior to any medical decision making. The contributors of the ER-Rx podcast are not affiliated with, nor do they speak on behalf of,  any medical institutions, educational facilities, or other healthcare programs.Support the show

infectious diseases one time uti urinary tract infections cystitis gentamicin references all amikacin tobramycin
The Elective Rotation: A Critical Care Hospital Pharmacy Podcast
738: Nebulized Tobramycin Vs Pseudomonas Gets an Evidence Boost

The Elective Rotation: A Critical Care Hospital Pharmacy Podcast

Play Episode Listen Later Aug 11, 2022 3:24


Show notes at pharmacyjoe.com/episode738. In this episode, I'll discuss nebulized tobramycin for bronchiectasis from pseuduomonas. The post 738: Nebulized Tobramycin Vs Pseudomonas Gets an Evidence Boost appeared first on Pharmacy Joe.

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The Elective Rotation: A Critical Care Hospital Pharmacy Podcast
738: Nebulized Tobramycin Vs Pseudomonas Gets an Evidence Boost

The Elective Rotation: A Critical Care Hospital Pharmacy Podcast

Play Episode Listen Later Aug 11, 2022 3:24


Show notes at pharmacyjoe.com/episode738. In this episode, I ll discuss nebulized tobramycin for bronchiectasis from pseuduomonas. The post 738: Nebulized Tobramycin Vs Pseudomonas Gets an Evidence Boost appeared first on Pharmacy Joe.

boost pseudomonas nebulized tobramycin
CCO Infectious Disease Podcast
HABP/VABP and Gram-Negative Resistance: Pathways to Early Effective Therapy

CCO Infectious Disease Podcast

Play Episode Listen Later Mar 15, 2022 101:43


In this episode, Keith S. Kaye, MD, MPH; Lilian Abbo, MD, FIDSA; and Jason M. Pogue, PharmD, discuss HABP/VABP and gram-negative resistance including:Epidemiology and burden of nosocomial bacterial pneumoniaPatient-specific risk factors for MDR pathogensImproving outcomes with the use of antibiogramsRecommended empiric therapy for clinically suspected VABPAntimicrobial resistance in HABP/VABPAlgorithms for gram-negative organism antibiotic-susceptibility testingUsing rapid diagnostic tests for HABP/VABPNew antimicrobial agents for MDR gram-negative infections with discussion of the 2021 IDSA guidance, and the following studies:ASPECT-NP: ceftolozane/tazobactam vs meropenemREPROVE: ceftazidime/avibactam vs meropenemRESTORE-IMI-1 imipenem/cilastatin/relebactam vs colistin + imipenemRESTORE-IMI-2: imipenem/cilastatin/relebactam vs piperacillin/tazobactamAPEKS-NP: cefiderocol vs meropenemCREDIBLE-CR: cefiderocol vs best available therapyProgram Director:Keith S. Kaye, MD, MPHChiefDivision of Allergy, Immunology and Infectious DiseasesProfessor of MedicineRutgers Robert Wood Johnson Medical SchoolNew Brunswick, New JerseyFaculty:Lilian Abbo, MD, FIDSAAssociate Chief Medical Officer in Infectious DiseasesJackson Health SystemProfessor of Infectious DiseasesDepartment of Medicine & Miami Transplant InstituteUniversity of Miami Miller School of MedicineMiami, FloridaJason M. Pogue, PharmDClinical ProfessorDepartment of Clinical PharmacyUniversity of Michigan College of PharmacyInfectious Diseases Clinical PharmacistMichigan MedicineAnn Arbor, MichiganContent based on a CME program supported by an educational grant from Merck Sharp & Dohme Corp.Follow along with a downloadable slideset at:https://bit.ly/3CEop6hLink to full program https://bit.ly/3i781lf

Cystic Fibrosis Review
Volume 6, Number 10

Cystic Fibrosis Review

Play Episode Listen Later Sep 15, 2016 24:29


Pseudomonas aeruginosa Eradication and Outcomes: Key Questions

Cystic Fibrosis Review
Volume 6, Number 6

Cystic Fibrosis Review

Play Episode Listen Later May 17, 2016 28:51


Trends in Inhaled Antibiotic Therapy

Medizinische Fakultät - Digitale Hochschulschriften der LMU - Teil 19/19
Untersuchungen zu Auftreten und Vermeidung der Anastomoseninsuffizienz nach tiefer anteriorer Rektumresektion durch eine lokale antimikrobielle Prophylaxe

Medizinische Fakultät - Digitale Hochschulschriften der LMU - Teil 19/19

Play Episode Listen Later Feb 22, 2016


In der Arbeit konnte gezeigt werden, dass mit einer topischen Dekontamination eine Reduktion der postoperativen Anastomoseninsuffizienzrate bei der tiefen anterioren Rektumresektion erreicht werden kann. Eine Vermeidung von nicht Anastomoseninsuffizienzassoziierten Infekten oder ein Einfluss auf die Mortalität konnte nicht beobachtet werden. Es zeigte sich ausserdem dass Patienten mit einer Anastomoseninsuffizienz ab dem 3. postoperativen Tag höhere CRP-Werte aufweisen und somit ein steigendes oder persistierend hohes CRP eventuell als Indiz für das Auftreten einer Insuffizienz gedeutet werden kann. Basierend auf den vorliegenden Daten sollte die topische Dekontamination mit Polymyxin B, Tobramycin, Vancomycin bei der tiefen anterioren Rektumresektion zur Vermeidung der Anastomoseninsuffizienz in Erwägung gezogen werden.

AHEAD OF THE CURVE: Cystic Fibrosis
Ahead of the Curve: The Diagnostic and Therapeutic Challenge

AHEAD OF THE CURVE: Cystic Fibrosis

Play Episode Listen Later Nov 29, 2013 81:57


Originally presented at the 2013 North American Cystic Fibrosis Conference, this program covers differentiation of CF classes and current/potential therapies and using the CFTR2 database.

Medizinische Fakultät - Digitale Hochschulschriften der LMU - Teil 03/19
Inhalative Antibiotikatherapie bei Cystischer Fibrose

Medizinische Fakultät - Digitale Hochschulschriften der LMU - Teil 03/19

Play Episode Listen Later Oct 14, 2004


Die vorliegende Arbeit beschäftigt sich mir der Frage nach der Effektivität von inhalativ appliziertem Colistin und Tobramycin bei Patienten mit Cystischer Fibrose. Es handelt sich um eine retrospektive Analyse von 308 Therapieepisoden bei 71 Patienten. Basis ist die Gegenüberstellung positiver und negativer Effekte. Als positiv werden die Eradikation oder die Konzentrationsabnahme der Erreger im Sputum gewertet, negativ sind Gleichbleiben und die Zunahme der Konzentration sowie die Superinfektion unter Therapie. Unter Tobramycin dominieren die positiven Effekte. Sie werden begünstigt, wenn Tobramycin bei jungen Patienten, in frühen Krankheitsstadien eingesetzt wird, sowie bei Besiedelung durch noch nicht mukoide Pseudomonas aeruginosa-Stämme, bei Tobramycin-sensitiven Erregern und hoher Dosierung bis zu 2x300 mg/d. Im Gegensatz dazu dominieren bei Inhalation von Colistin die negativen Effekte. In keinem Fall unterschied sich die Wirkung von derjenigen der Kontrollepisoden. Anders als bei Tobramycin ließ sich für Colistin keine Korrelation zwischen der Empfindlichkeit und dem Verlauf der Konzentration der Erreger feststellen. Dies deutet auf eine zu niedrige Dosierung von Colistin hin. Sie kann jedoch im Gegensatz zur Situation bei Tobramycin wegen der Nebenwirkungen nicht wesentlich erhöht werden. Bei der CF werden Antibiotika auch zur Prophylaxe, d.h. zum Verhindern einer Kolonisation mit P.aeruginosa eingesetzt. Weder bei Colistin- noch bei Tobramycin-Inhalation konnte ein prophylaktischer Effekt festgestellt werden.