Organ for breathing air
James Leman (@the_carnivorist) nearly died after following a strict vegetarian for decades and then vegan diet for 5 years before finding an animal-based carnivore diet and resolving a host of health issues. He's endured multiple hospitalizations, autoimmune issues, anxiety, depression, and many other health problems before coming to this way of eating. Instagram: https://www.instagram.com/the_carnivorist/ This episode is brought to you by Optimal Carnivore. Do you struggle to eat organ meat? Optimal Carnivore was created by Carnivores for Carnivores. They created a unique organ complex from grass-fed animals in New Zealand. It includes 9 different organs - Liver, Brain, Heart, Thymus, Kidney, Spleen, Pancreas, Lung etc. Taking 6 capsules is the same as eating an ounce of raw organ meat from the butcher. Get 10% off your order by going to https://amzn.to/3hSXXtu and using the code: carnivore10 at checkout! (currently only shipping within the US) LMNT is offering a free sample pack along with any regular purchase when you use my custom link drinklmnt.com/carnivorecast . The LMNT Sample Pack includes 1 packet of every flavor. This is the perfect offer for 1) anyone who is interested in trying all of our flavors or 2) wants to introduce a friend to LMNT. Go to drinklmnt.com/carnivorecast to claim this awesome deal! What questions would you like answered or who would you like to hear from in the carnivore or research community? Let me know on Twitter, Instagram, and Facebook.
What is involved in coming home and living after a lung transplant? Learn from this week's guest. Stevan shares his experience after a lung transplant: complex medication regimen, immunosuppression, increased risk for skin cancer, and vital caregiver help.
Indy Noir Punk-Dayton Buyout guitar God, and super duper friendly Duder, Nick Kizirnis is a Dayton Music scene juggernaut. His new single, "Way To Me" features the hauntingly melodious voice of Lung's Kate Wakefield, with help from Son Volt's own Mark Patterson, as well as co-producer Patrick Himes. Available streaming everywhere, as well as Bandcamp, where you can order this bad boy on clear, lathe cut, 7" vinyl. Dig it!
Cancer innovation has been a longstanding priority in the current administration. But sometimes overlooked is some of the nation's most sophisticated lung cancer research underway at the Department of Veterans Affairs. This includes applying capacities like modernized electronic health records and artificial intelligence to support groundbreaking innovation. Dr. Michael Kelley, director of the National Precision Oncology Program, and Kenute Myrie, portfolio manager at the VA Office of Research and Development, discuss how the agency is advancing understanding of cancer and improving long-term health outcomes for veterans.
Kỷ nguyên Elizabeth II đóng lại sau 70 năm, cánh cửa đến triều đại của tân quốc vương Charles III mở ra. Lên ngôi ở tuổi 73, vị tân vương phải đối mặt với nhiều thách thức không nhỏ, không chỉ bởi bối cảnh xã hội thay đổi và tình hình bất ổn của nền kinh tế tại Anh mà cả những bê bối khiến danh tiếng của Charles III bị tổn hại trong thời gian qua. Trong khi hàng trăm ngàn người tiếp tục khóc thương cho sự ra đi của Nữ hoàng Elizabeth II trước điện Buckingham tại Luân Đôn, thần dân Anh Quốc cũng như công luận thế giới dần chuyển sự chú ý sang người thừa kế ngai vàng - vua Charles III. Sau 73 năm chuẩn bị, Charles III chính thức đăng quang vào Thứ Bảy, 10/09. Quốc ca Anh, từ nay trở thành “God Save The King” – “Xin chúa phù hộ quốc vương”, thay vì (God save the Queen). Triều đại Charles Đệ Tam được mở ra trong thời đại mà tương lai của cả vương quyền lẫn đất nước mà ông cai trị đều không vững chắc. Charles III không phải là diện mạo mới của hoàng gia Anh Nếu như cố Nữ hoàng đại diện cho sự ổn định cho cả xã hội Anh Quốc và 14 quốc gia khác mà bà trị vì, thì những di sản bà để lại cho Charles III khá phức tạp, theo The Conversation. Vị tân vương phải đối mặt với nhiều thách thức : làm sao có thể duy trì chế độ quân chủ ở thời hiện đại, giống như cách mà Elizabeth II đã làm sau Thế Chiến Thứ Hai. Nhà sử học Anna Whitelock, chuyên nghiên cứu về nền quân chủ tại đại học Luân Đôn, cho rằng Charles III sẽ không có nhiều nhiệt huyết với tư cách là một tân vương khi lên ngôi ở tuổi 70. Ông cũng không phản ánh, hay đại diện cho một diện mạo mới của nền quân chủ. Theo nhà sử học, dù công luận vẫn đổ lỗi cho ông về số phận bi thảm của công nương Diana, nhưng giới trẻ dần dần cũng sẽ quên đi. Bà nói thêm : “Điều tốt nhất mà Charles có thể làm trong cương vị tân vương, đó là tính lãnh đạm và những cái nhún vai của ông ấy. Một điều chắc chắn là Charles III sẽ không thể nổi tiếng hay có sức ảnh hưởng như thân mẫu của mình”. Vị vua vận động hành lang ? Nếu như Elizabeth II cẩn thận, không đưa ra quan điểm chính trị thì Charles III khi còn là hoàng tử xứ Wales, lại thẳng thắn đưa ra ý kiến trong các cuộc tranh luận về kiến trúc, nông nghiệp, hay môi trường. Năm 2015, The Guardian đã công bố những lá thư của Charles, vận động chính phủ của Tony Blair về các vấn đề mà ông quan tâm. Theo ông Luc Bort, giảng viên danh dự về văn minh Anh tại đại học Paul Valéry ở Montpellier, trả lời trên RFI Pháp ngữ, việc Charles thiếu sự trung lập trong chính trị, có thể là một trở ngại lớn. “Tôi cho rằng ông ấy hiểu được là từ giờ phải học được cách giữ im lặng và phải làm được điều đó. Nhưng có lẽ Charles III sẽ gặp khó khăn trong các hồ sơ về môi trường (chủ đề mà ông đặc biệt quan tâm). Ví dụ như thủ tướng Liz Truss vừa thông qua văn bản cho phép sử dụng kỹ thuật khai thác mỏ bằng thuỷ lực. Chúng ta sẽ xem liệu ông ấy có đưa ra phát biểu công khai nào hay không. Nhưng điều này sẽ không được tiếp nhận tốt. Charles từ lâu đã được xem như là một nhà vận động hành lang trong nhiều lĩnh vực. Ông đã can thiệp vào các hồ sơ về chỉnh trang đô thị, để kiếm lợi cho câu lạc bộ golf của hoàng gia. Tuy nhiên, ông cũng có những hành động rất hào phóng, tích cực hoạt động trong các tổ chức từ thiện. Charles III đã từng ám chỉ muốn thay đổi chế độ quân chủ, theo hướng can thiệp nhiều hơn vào chính trị. Đó là những ý tưởng mà những người thân cận của ông đã loan truyền 15 năm trước. Liệu đó có phải chỉ là một quả bóng thăm dò hay không ? Tôi chưa có câu trả lời.” Theo Fabrice Rousselot, giám đốc ban biên tập của trang The Conversation ở Pháp, việc Charles III ít kín tiếng hơn cố Nữ hoàng về quan điểm chính trị, có thể đe dọa vai trò được quy định trong Hiến Pháp Anh : một vị quân vương trị vì nhưng không cai trị. Khối Thịnh Vượng Chung – quyền lực mềm của Anh Quốc dưới tay Charles III Elizabeth Đệ Nhị không chỉ là Nữ hoàng của Vương Quốc Anh mà cả 14 nước khác nữa, trong đó có Canada và New Zealand. Trong suốt thời gian trị vì, bà cũng đã chứng kiến nhiều nước rời khỏi bàn tay của vương quyền và trở thành một nước độc lập. Năm 2021, một năm trước khi Charles III kế vị, đảo Barbados đã trở thành nước cộng hoà độc lập. Vào đầu năm 2022, một số đảo ở vùng Caribe cũng đã bày tỏ mong muốn độc lập. Sự ra đi của nữ hoàng có thể là cơ hội cho một số quốc gia và lãnh thổ xem xét lại quan hệ với chế độ quân chủ Anh Quốc. Đây là một thách thức không nhỏ đối với tân vương : làm sao duy trì vương quyền bên ngoài lãnh thổ Anh Quốc cũng như mức độ ảnh hưởng trong khối Thịnh Vượng Chung - gồm hơn 50 nước, đa số từng là thuộc địa của Anh Quốc – công trình cả đời Nữ hoàng. Tác giả của cuốn “The Queen”, một cuốn tự truyện của hoàng gia, ông Matthew Dennison nói về tương lai của các vương quốc thuộc khối Thịnh Vượng Chung, được Reuters trích dẫn: “Vào năm 2018, khối Thịnh Vượng Chung đã nhất trí để hoàng tử xứ Wales, tức vua Charles III hiện nay, kế nhiệm vị trí đứng đầu của Elizabeth II, mặc dù đây không phải là vị trí “mẹ truyền con nối”. Bởi lãnh đạo khối Thịnh Vượng Chung, trên thực tế, không được tự động truyền lại cho người nối dõi giống như trong hoàng gia Anh. Thế nhưng thoả thuận này đã được thực hiện. Tôi cho rằng vị vua mới cũng được đánh giá cao trong khối. Triều đại Elizabeth kết thúc, tân vương thừa kế 14 vương quốc thuộc Khối thịnh vượng chung. Tôi nghĩ rằng chúng ta cũng sẽ sớm biết liệu các nước này có quyết định ở lại với hoàng gia Anh, hay trở thành các nước cộng hòa độc lập trong Khối thịnh vượng chung. Theo tôi, quan điểm của Charles III về việc này đó là để cho họ tự quyết định số phận của họ, giống như đối với Bardados.” Triều đại mới với những rủi ro suy thoái kinh tế Trong vòng chưa đầy một tuần, người dân Anh Quốc có tân thủ tướng Liz Truss, có tân vương Charles III và chịu quốc tang nữ hoàng Elizabeth II. Một trang sử mới được mở ra, cho tân lãnh đạo về chính trị cũng như cho vị quân vương - biểu tượng quyền lực mềm của hoàng gia Anh. Trang sử đó sẽ được viết như thế nào khi mà Anh Quốc đang phải đối mặt với nhiều vấn đề xã hội. Có những thời điểm, lạm phát lên đến 10%, cao nhất từ năm 1981. Mối đe doạ suy thoái kinh tế rình rập. Ngoài những tác động của Brexit, Anh Quốc, cũng như nhiều nước trên thế giới, cũng đang phải chịu hậu quả từ cuộc chiến ở Ukraina. Giá nhiên liệu, giá nhà, giá thực phẩm tăng phi mã, ảnh hưởng nghiêm trọng đến sức mua của người dân. Phong trào không thanh toán tiền điện - “Dont pay” được phát động từ tháng 8 vẫn thu hút sự tham gia đông đảo của hàng trăm ngàn người Anh. Một phóng sự của tờ Le Parisien chỉ ra rằng nhiều người Anh lo ngại về tương lai của họ. Một số quan tâm đến hiện thực - sức mua giảm, không đủ tiền chi trả phí sinh hoạt hơn là đám tang của cố Nữ hoàng cũng như lễ đăng quang của Charles III. Những sự kiện này có thể phải chi đến hàng triệu bảng Anh. Theo nhà sử học Anna Whitelock, được AP trích dẫn, hiện tại tân vương vẫn được dân Anh đón nhận một cách nồng nhiệt, nhưng cũng cần phải chờ qua giai đoạn tang tóc này. Bà đặt câu hỏi : “Liệu lễ đăng quang của tân vương có được tổ chức một cách xa hoa hay không, vào thời điểm mà nước Anh đang phải đối mặt với cuộc khủng hoảng năng lượng, khủng hoảng chi phí sinh hoạt. Nếu vậy thì điều này sẽ trở thành một nỗi ám ảnh về đặc quyền của một người đàn ông da trắng trở thành vua. Các chi phí khổng lồ để tổ chức của buổi lễ, sẽ trở thành tiếng xấu của hoàng gia đối với công chúng ở Vương Quốc Anh. Điều này có lẽ sẽ làm lu mờ đi sự khởi đầu triều đại của tân vương.” Quân vương mới có hiện đại hóa chế độ quân chủ ? Charles III cũng là vị vua lên ngôi ở tuổi già nhất trong lịch sử hoàng gia Anh, 73 tuổi. Một câu hỏi khác được đặt ra là liệu ông chỉ là một vị vua chuyển tiếp triều đại, rồi sau đó thoái vị truyền ngôi cho hoàng tử xứ Wales – Wiliam, con trai cả của mình hay ông sẽ đảm nhận trách nhiệm, tiếp tục con đường hiện đại hoá chế độ quân chủ trong thời gian trị vì, ngắn hơn mẹ mình rất nhiều. Giảng viên về văn minh Anh Quốc Luc Bort, trả lời trên RFI Pháp ngữ : “Hiện đại hoá chế độ quân chủ có thể được làm theo nhiều cách khác nhau. Tôi cho rằng Charles III có thể thu hút những thần dân còn nhiều nghi hoặc về khả năng của tân vương nếu ông xoá bỏ đi những đặc quyền của hoàng gia. Bởi vì hiện tại, cuộc sống hoàng tộc được chi trả bằng tiền thuế của người dân. Ngay cả những người rất quý mến nữ hoàng Elizabeth II cũng thấy đây là điều không đúng. Hiện đại hóa chế độ quân chủ cũng có nghĩa là đến gần hơn với cách sống của toàn bộ xã hội Anh. Tôi nghĩ Charles III sẽ giống như cố Nữ hoàng, muốn tránh thoái vị. Vì ông chú quá cố Edward, người thoái vị (nhường ngôi cho cha Elizabeth để theo đuổi tình yêu cá nhân) không phải là một kỷ niệm đẹp đối với cả hoàng tộc và cả người Anh.” Trách nhiệm đặt lên vai tân vương Charles Đệ Tam không nhỏ, làm sao để duy trì và không phá hỏng những di sản mà Nữ hoàng để lại. Trong khi Anh Quốc và 14 quốc gia khác công bố tân vương mới, thì phong trào #notmyking – không phải vua của tôi, bùng phát trên mạng xã hội Twitter, lên đến hơn 50 ngàn lượt chia sẻ. Mọi người dùng thẻ gắn này để phản đối triều đại mới. Nhiều ý kiến cho rằng, chế độ quân chủ nên kết thúc cùng với sự ra đi của Elizabeth II. Cho đến nay, vẫn chưa rõ thế nào là “thành công” đối với nền quân chủ Anh ở thế kỷ 21. Phải chăng là ảnh hưởng, sự dung hoà, làm tấm gương tốt, hay chỉ đơn giản là làm sao để có thể tồn tại ?
Lung cancer is one of the most commonly diagnosed type of cancer and so it is fitting that we start the first of our disease-specific oncology series with this diagnosis. This week, we round out our discussion of early stage lung cancer treatment!* When deciding if a patient can get surgery upfront or not, remember the three “Fellow on Call” criteria for early stage lung cancer: - Mass invading other structures or mediastinum- Central lymph nodes (single digit)- Tumor >7 cm* If surgery is NOT an option at this time, where do we go from here?- Treat with upfront concurrent definitive chemoradiation- Treat with “induction” chemotherapy or induction concurrent chemoradiation**If surgery is/may be possible***What are the goals of “induction” treatments? - Eradicate microscopic disease- Improved local control, possibly shrinkage- Adding radiation may allow you to downstage tumor or lymph nodes to have a possible improvement in surgical outcomes* What sorts of discussions are being had a thoracic tumor board in patients with newly diagnosed early stage NSCLC? - Is the patient a surgical candidate?- If the patient is not a surgical candidate, then what are the options:--Definitive concurrent chemoradiation (usually) followed by immunotherapy---Pearl 1: Always choose this if surgeon thinks the patient is unresectable in general even with an induction approach---Pearl 2: Always choose this if 2 out of 3 criteria we discussed above are met---Pearl 3: Always choose this if N3 disease- “Induction” regimen with either chemotherapy alone or concurrent chemoradiation followed by surgery * What's the idea behind “induction” chemo or chemoradiation? - There is a chance that patients with these high risk features may already have micrometastatic disease, so treatment upfront can help address that- There is a chance that after surgery, patient may suffer deconditioning, which may preclude the use of chemo +/- radiation (up to 90% of patients are often eligible for chemoradiation before surgery; this drops to ~60% after surgery)- Local disease control to achieve the best possible surgical outcome (R0 resection) and also prevent any microscopic residual disease from then having the opportunity to spread systemically, especially in areas where the mass may be adjacent to many blood vessels or lymph nodes* What to treat with in the neoadjuvant setting?- Platinum containing regimens (“platinum doublets”):-- Carboplatin + paclitaxel-- Cisplatin + etoposide-- Cisplatin + gemcitable-- Cistplain + pemetrexed- Can combine this with radiation* How does the data about chemotherapy+IO in the neoadjuvant setting fit in here (CHECKMATE 816)?- In patients with Stage IIB to IIIA (8th edition) WITHOUT EGFR or ALK mutation, treatment with NEOADJUVANT chemotherapy q3w x3 cycles (most got cisplatin based therapy) + nivolumab 360mg q3w x3 cycles resulted in improved event free survival (31.6 months vs. 20.8 months) AND pathological complete response was 24.0% vs. 2.2%- Current NCCN guidelines state that if nivolumab is used in neoadjuvant setting, it should not be used in adjuvant setting- There is still uncertainty about how this fits into treatment compared to “traditional” neoadjuvant approaches with chemo+/-radiation*So after neoadjuvant treatment, does everyone go to surgery?- Always re-assess the status of the disease; if there is progression of disease, then will go to definitive chemoradiation- Discuss with surgeons to confirm if the patient is still a surgery candidate* If patient undergoes surgery, then what?- If patient got neoadjuvant therapy and an R0, then they are done with treatment- If R0 resection was not able to achieved, then either radiation “boost” to the area (if they previously got radiation), a course of radiation (if they just got induction chemo) or re-resection- We discuss the adjuvant setting in more detail in Episode 026 (https://www.thefellowoncall.com/tfocpodcast/episode-001disclaimer-wfhgf-ml3b6-9m66a-8rrc4-k8w87-x7xdd-wrzye-4xg8x-t73gt-cxc5s-nmg8f-cfyd6-hgs35-5pcwx-tf6dh-trggt-xzkt7-923gg-rpjzx-6s36p-hk27n-bbpgx-jymml-9lfam-76m4s)** If surgery is not possible*** If patient cannot go through to surgery Definitive chemoradiation:- Same chemotherapy agents as above, but treatment course is longer.- For instance, for NSCLC, total 60Gy in 2Gy divided fractions (5 days/week, 6 weeks of treatment) with chemotherapy* Additional therapy after chemoradiation (PACIFIC Trial) - Found that “consolidation” durvalumab 44% PFS 18 months vs 20% 5year survival benefit 40% vs. ~30% without treatmentReferences:https://www.nccn.org/guidelines/guidelines-detail?category=1&id=1450 - NCCN Lung Cancer guidelines https://www.nejm.org/doi/full/10.1056/nejmoa1709937 - PACIFIC Trial (NEJM 2017)https://www.nejm.org/doi/10.1056/NEJMoa2202170 - CHECKMATE 816 (NEJM 2022) Please visit our website (TheFellowOnCall.com) for more information Twitter: @TheFellowOnCallInstagram: @TheFellowOnCallListen in on: Apple Podcast, Spotify, and Google Podcast
When talking soybean harvest losses, all the focus is on the header. But for canola, losses add up at the header and through the combine. Understanding how to manage those losses is a mix of agronomy, mechanical know-how, and patience. To break down the process, this episode of The Agronomists features Mike Staton, soybean expert... Read More
When talking soybean harvest losses, all the focus is on the header. But for canola, losses add up at the header and through the combine. Understanding how to manage those losses is a mix of agronomy, mechanical know-how, and patience. To break down the process, this episode of The Agronomists features Mike Staton, soybean expert... Read More
In this episode of Microbe Talk, Charlie talks to Dr Jonathan Cox about his team's newly published research on a surprising use for Manuka honey. Music: Leatherbound by Blue Dot Sessions (www.sessions.blue)
The lungs are the gateway to our breath. Often in life we allow things and people to "take our breath away" and suffer with respiratory issues that can go on for the duration of our lives. Who and what needs to be removed from your life so that you can finally catch your breath?
Ryan Talbot (https://www.instagram.com/_ryan_talbot_/) is an All-American Decathlete for Michigan State University. After several injuries and health issues, Ryan began a carnivore diet in the midst of his decathlete season as an NCAA Div 1 athlete. He went on to win the Big Ten Championships on carnivore, break the school record, and compete in the NCAA National Championship. He's recently appeared on Boundless Body Radio with Casey Ryan Ruff and the Plant Free MD podcast with Dr. Anthony Chaffee. This episode is brought to you by Optimal Carnivore. Do you struggle to eat organ meat? Optimal Carnivore was created by Carnivores for Carnivores. They created a unique organ complex from grass-fed animals in New Zealand. It includes 9 different organs - Liver, Brain, Heart, Thymus, Kidney, Spleen, Pancreas, Lung etc. Taking 6 capsules is the same as eating an ounce of raw organ meat from the butcher. Get 10% off your order by going to https://amzn.to/3hSXXtu and using the code: carnivore10 at checkout! (currently only shipping within the US) LMNT is offering a free sample pack along with any regular purchase when you use my custom link drinklmnt.com/carnivorecast . The LMNT Sample Pack includes 1 packet of every flavor. This is the perfect offer for 1) anyone who is interested in trying all of our flavors or 2) wants to introduce a friend to LMNT. Go to drinklmnt.com/carnivorecast to claim this awesome deal! What questions would you like answered or who would you like to hear from in the carnivore or research community? Let me know on Twitter, Instagram, and Facebook.
Si talks about the lung operation he's been eagerly awaiting and why now is the right time. Godwin says Si has always been full of hot air. Si wonders who invented the very first alphabet. What's the most unusual thing the boys have seen in the woods? Si wishes he could be a flying squirrel, but he will NOT join John-David on any roller coasters. Godwin relives his first roller coaster ride on Space Mountain. Plus, the boys give some advice to a fan who's worried about his wife & her family not being Christians. https://athleticgreens.com/duck — Get a FREE 1-year supply of Vitamin D & 5 FREE travel packs with your first purchase! https://rocketmoney.com/duck — Save up to $700 a year with Rocket Money! https://www.mypillow.com/duck — Get up to 66% OFF with promo code DUCK! -- Learn more about your ad choices. Visit megaphone.fm/adchoices
This month—two studies on COVID-19! Daniel R. Goldstein, MD, Editor-in-Chief of JHLT, is taking a short break, so the episode is hosted by Digital Media Editor Erika Lease, MD. Both COVID-19 studies come from the September issue of The Journal of Heart and Lung Transplantation, and in the episode, you'll learn more about each study and their authors. First, the editors speak with Yael Peled, MD, Medical Director of the Heart Transplant Service at the Sheba Medical Center in Ramat Gan, Israel. She's the first author on a paper entitled “Fourth BNT162b2 vaccination neutralization of omicron infection after heart transplantation.” Dr. Lease and Marty Tam, MD, interview Dr. Peled about the study, which examples how IgG and neutralizing antibodies responded to a fourth BNT162b2 dose in heart transplant recipients against the omicron and delta variants versus the wild-type virus. Next, we hear from C.T. Gan, MD, PhD, Consultant in Respiratory Medicine and Lung Transplantation at University Medical Center Groningen, on his study, “The effect of COVID-19 on transplant function and development of CLAD in lung transplant patients: a multicenter experience.” Dr. Lease and Van-Khue Ton, MD, discuss the study with Dr. Gan, including questions on management strategies for COVID-19 in lung transplant patients, lung function improvements after COVID-19 recovery, and potential follow up studies. Follow along in the September issue at www.jhltonline.org/current, or, if you're an ISHLT member, log in at ishlt.org/journal-of-heart-lung-transplantation. Don't already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at www.ishlt.org for a free subscription, or subscribe today at www.jhltonline.org. This episode of JHLT: The Podcast, but not the studies within, is sponsored by Bayer Pharmaceuticals.
Lung cancer is one of the most commonly diagnosed type of cancer and so it is fitting that we start the first of our disease-specific oncology series with this diagnosis. An important component of treatment in lung cancer (and many other cancers) is the use of radiation. This week, we continue our discussion about the fundamentals of Radiation Oncology with our guest, Dr. Evan Osmundson. *We hear the terms “hypo-fractioned” and “hyper-fractionated” radiation. What do those mean?- Fractionation, that is breaking up the total dose of radiation into smaller ones, has allowed patients to tolerate the radiation better. The repeat exposure allows the healthy tissue to repair, whereas the tumor is not able to heal as well- Standard fractionation involves keeping the maximum dose per session at 1.8-2Gy/fraction. - Hyper-fractionation is when a patient gets multiple doses per day, each less than 2Gy. This is important in small cell lung cancer, where the standard dose of radiation is 1.5Gy twice daily- Hypo-fractionation os when larger doses are given in each session, typically larger than 2.5-3Gy, often 4-5Gy per fraction. This is analogous to SBRT. *With regards to SBRT, how do you determine the number of sessions? - Typically 3-5 sessions, and this is based on data run through their computer algorithm that allows the dose to be tumoricidal. - More sessions (more likely 5 sessions) if central tumor (
Video animation by: Big Flowers Intro/Outro beat by: BLOODBLIXING The Hook (0:21). Main Body of Discussion (2:00). Few albums build an entirely fresh and distinct musical universe quite like ShrapKnel's Metal Lung. Within seconds, the duo of PremRock and Curly Castro bring you on a 40+ minute journey that features a combination of A1 lyricism, and production that is wildly psychedelic and atmospheric. Coming off the heels of two great solo albums respectively, and the debut ShrapKnel record that was great in its own right, my expectations couldn't have been higher for Metal Lung... and I am very happy to say that these expectations were blown out of the water. The dynamic duo of Curly Castro and PremRock joined the show to deep-dive into the creation of Metal Lung, in the 3rd installment of the Album Alchemy series. Listen on to hear how one of the best albums of 2022 was conceived. Buy Metal Lung here: https://shrapknel.bandcamp.com/album/metal-lung Follow PremRock on Twitter here: https://twitter.com/PlanetPremRock?s=20&t=Y_WTB0pKsxoDf4YvG4pItg Follow Curly Castro on Twitter here: https://twitter.com/Curly_Castro?s=20&t=Y_WTB0pKsxoDf4YvG4pItg Follow PremRock on Instagram here: https://www.instagram.com/premrock/?hl=en Follow Curly Castro on Instagram here: https://www.instagram.com/curlycastro/?hl=en -- Fiending for some more quality rap content? Visit the RMPP website: https://rmpp.squarespace.com/ Want to support and help us grow? Become a RMPP Patron, and gain access to exclusive content: https://www.patreon.com/therapmusicplugpodcast Looking to connect? DM me @rapmusicplugpod on Twitter and Instagram, or shoot me an email at firstname.lastname@example.org
The lungs represent our ability to take in life, to breathe life force energy, the essential energetic substance required to maintain vitality.In this human experience of life, we have the opportunity to also take in and feel the full rainbow of emotions. Joy, sorrow, peace, compassion, anger, love, greed, grief, envy, anxiety, and absolutely everything in between...We are designed to fully feel these emotions - energy in motion through the body and mind.When faced with difficult feelings, emotional energy can become stuck. Conscious or not, the stagnant energy can cause or exacerbate any number of physiologic conditions.It just so happens that grief is the emotion most associated with chronic lung conditions. Most adults who suffer with asthma, chronic bronchitis, emphysema, or other lung and breathing issues can identify with this grief...Lung problems involve depression, tiredness, fear of taking in life, or not feeling worthy of living.Tune in as we explore these deep topics in this week's Wisdom Wednesday.Join the conversations live on YouTube every Wednesday: https://www.youtube.com/alterhealthSome highlights from today's WW episode on HEART ENERGY...The brain-lung connection and the lung brain connection - how to navigate this two-way street between lungs and the autonomic nervous systemThe emotional/energetic patterns that may contribute to lung issues, including grief, depression, feeling unworthy, and the the suppression on these feelings. How we find freedom in fully feeling, embracing, integrating, and transcending stuck emotionsOur emotions are like weather patterns - nothing to control or manage but rather understand and acceptThe psychological immune system empowers us to relate to our emotions in a healthy way, trusting that alllll thoughts and emotions passLinks to some more good stuff- Get weekly Meal Guides: https://www.alter.health/meal-guides- Stay connected on Telegram: https://t.me/alterhealth - Cleanse with Us during the next Alter Health Cleanse: https://www.alter.health/cleanse- Work with us in the Thrive on Plants program: https://www.alter.health/thrive-on-plants- ATTN Health Practitioners! Learn more and apply to the Plant Based Mind Body Practitioner Program: https://www.alter.health/pbmb-practitionerPeace and Love.
When suffering with chronic lung conditions, it's not so common to consider food choices and nutritional status as important factors in prevention and healing.Air quality/pollution, smoking, and environmental toxin exposure are the much more traditional risk factors for lung conditions like lung cancers, COPD, and asthma.BUT, nutritional status is SO huge for so many reasons.Today we overview some of the empowering nutritional science that demonstrates the role whole food plant based eating has in both preventing and reversing the most common chronic lung conditions.When we understand the mechanisms of the diseases like COPD, asthma, and of course cancer, it's plain to see how optimizing nutritional status can play a huge part in reducing oxidative stress, eliminating chronic inflammation, and balancing immune status to defend against both acute respiratory illness (like pneumonia, which is actually responsible for a large number of deaths annually, especially amongst elderly) as well as the chronic and debilitating conditions.As always, you can join us live each Monday at 12 PT / 3 ET on the Alter Health YouTube Channel! https://www.youtube.com/alterhealthSome highlights from today's episode on Heart Health...How hidden toxins in air can irritate lungs and cause oxidative damage to set the stage for more chronic conditionsHow COPD (chronic bronchitis and emphysema) causes airway destruction overtime and clear ways to stop the progression of diseaseThe common immune imbalance that is associated with asthma - airflow obstruction and the inability to properly ventilate lungsSpecific constituents in foods that either promote healing or exacerbate dis-ease in lungsAn inspiring testimonial of asthma reversal in an adult from whole food plant based eating and lifestyle healingLinks to some more good stuff- Get the Alter Health weekly WFPB Meal Guides: https://www.alter.health/meal-guides- Cleanse with Us during the next Alter Health Cleanse: https://www.alter.health/cleanse- Work with us in the Thrive on Plants program: https://www.alter.health/thrive-on-plants- ATTN Health Practitioners! Learn more and apply to the Plant Based Mind Body Practitioner Program: https://www.alter.health/pbmb-practitionerPeace and Love.
Vaping seems to have taken over the world in the past few years - one minute it doesn't exist, the next every teenager and their mum is sucking on an e-cig. It seems that vapes are safer than smoking, but that's not a very high bar... At least one major question remains to be answered: Is it safe to vape, or is vaping dangerous for your health? Grab our merch now: http://normalcitizen.store You can WATCH the podcast over on our YouTube channel: http://youtube.com/SciGuys Help keep the show running by supporting us on Patreon! http://patreon.com/sciguys If you'd like to see more of us, follow our socials! Website sciguys.co.uk TikTok https://www.tiktok.com/@sciguys Twitter http://twitter.com/SciGuysPod Instagram http://instagram.com/SciGuysPod Facebook http://facebook.com/SciGuysPod Follow the SCI GUYS @notcorry / @lukecutforth References & Further Reading What is Vaping? https://www.nhs.uk/live-well/quit-smoking/using-e-cigarettes-to-stop-smoking/ https://nida.nih.gov/publications/drugfacts/vaping-devices-electronic-cigarettes https://www.bbc.co.uk/news/business-61914166 https://okvape.co.uk/blog/vaping-beginners/brief-history-of-e-cigarettes/ Vaping & Nicotine Safety https://www.cdc.gov/tobacco/basic_information/e-cigarettes/Quick-Facts-on-the-Risks-of-E-cigarettes-for-Kids-Teens-and-Young-Adults.html https://www.ccjm.org/content/86/12/789.long https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7274878/ https://www.sciencedirect.com/science/article/pii/S0163725821000395?via%3Dihub https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7285995/ https://www.cancerresearchuk.org/about-cancer/causes-of-cancer/smoking-and-cancer/is-vaping-harmful https://www.bhf.org.uk/informationsupport/heart-matters-magazine/news/e-cigarettes https://www.health.harvard.edu/blog/can-vaping-damage-your-lungs-what-we-do-and-dont-know-2019090417734 https://www.lung.ca/lung-health/vaping-what-you-need-know#:~:text=Lung%20disease%3A%20Vaping%20can%20make,%2C%20in%20some%20cases%2C%20death. https://ukhsa.blog.gov.uk/2018/02/20/clearing-up-some-myths-around-e-cigarettes/ https://www.bupa.co.uk/newsroom/ourviews/is-vaping-harmful https://www.hopkinsmedicine.org/health/wellness-and-prevention/5-truths-you-need-to-know-about-vaping#:~:text=1%3A%20Vaping%20is%20less%20harmful,many%20of%20which%20are%20toxic. https://www.cdc.gov/tobacco/basic_information/e-cigarettes/severe-lung-disease.html Nicotine https://www.britannica.com/science/nicotine https://www.bat.com/nicotine
An article came out in The Lancet, one of the most respected medical journals, saying that cancer deaths from metabolic risk grew the most over the last 10 years. Dr. Martin says it's an astonishing headline but unfortunately the mainstream media won't be picking it up. We live in a different world now with some cancers occurring so rapidly. Lung cancer is still the number one killer, but not because of smoking. It's because of aldehydes! Join Dr. Martin as he explains why cancer is on the rise and how it's linked to metabolic disease. It's now being reported that 9 out of every 10 people are metabolically unwell!
Dr. Scott Solomons (@drscottsolomons) has been a dentist since 1989 and is a functional medicine practitioner. He combines dentistry, nutrition, and general health concepts to enable his patients to heal better and stay healthy longer. He received his DDS from Colombia University and is a member of several dental associations as well as paleo and primal societies such as the Ancestral Health Society and the Weston A Price Foundation. He is also on the Medical Advisory Board of the Kresser Institute for Functional and Evolutionary Medicine. Instagram: https://www.instagram.com/drscottsolomons/ This episode is brought to you by Optimal Carnivore. Do you struggle to eat organ meat? Optimal Carnivore was created by Carnivores for Carnivores. They created a unique organ complex from grass-fed animals in New Zealand. It includes 9 different organs - Liver, Brain, Heart, Thymus, Kidney, Spleen, Pancreas, Lung etc. Taking 6 capsules is the same as eating an ounce of raw organ meat from the butcher. Get 10% off your order by going to https://amzn.to/3hSXXtu and using the code: carnivore10 at checkout! (currently only shipping within the US) LMNT is offering a free sample pack along with any regular purchase when you use my custom link drinklmnt.com/carnivorecast . The LMNT Sample Pack includes 1 packet of every flavor. This is the perfect offer for 1) anyone who is interested in trying all of our flavors or 2) wants to introduce a friend to LMNT. Go to drinklmnt.com/carnivorecast to claim this awesome deal! What questions would you like answered or who would you like to hear from in the carnivore or research community? Let me know on Twitter, Instagram, and Facebook.
Lung cancer is one of the most commonly diagnosed type of cancer and so it is fitting that we start the first of our disease-specific oncology series with this diagnosis. An important component of treatment in lung cancer (and many other cancers) is the use of radiation. Here, we discuss the fundamentals of Radiation Oncology with our guest, Dr. Evan Osmundson. Basic vocabulary: - Fraction/Fractionation: The total dose of radiation divided into smaller doses - Grey: Unit of measure of radiation being delivered in each session - Bragg-Peak effect: Specific to proton therapy (as opposed to photon therapy). It describes the sharp increase in concentration of the energy when hitting the tumor, while minimizing the effects to surrounding tissue. - Radiosensitizing chemotherapy: small doses of chemotherapy used to make the cells more responsive to the deleterious effects of radiation Fundamentals of radiation oncology: *When we make a referral to RadOnc, what happens then? - Send over any available imaging that is available - Team reviews the imaging to ensure that staging is completed - Simulation scan: Uses a CT scan to “simulate” the treatment; specifically map out the tumor and the surrounding organs/structures. Multidisciplinary team reviews the scan to maximize the dose to the tumor and minimizes damage to surrounding structures. - Based on the scans, they test run the treatment on a model to ensure that the simulation on the computer is able to be replicated on a model. - The above is why it can take a while for treatment planning to take place*What sorts of imaging modalities are important to have for patients prior to getting to Rad Onc? - Send prior CT imaging - If planning for radiation to the brain, should get thin-sliced MRI w/ and w/o contrast - If prostate cancer, also consider getting MRI*Many patients express concern about the “mask fitting” - what is that? - To ensure that the same dose of radiation is administered each time, it is important for the patient to remain very still and/or the same position every session. The mask is custom fit to ensure patient is in the correct position. *How do you determine the “maximum dose” of radiation in the mediastinal area is? - The maximum dose tolerance is dependent on the structure in question. A structure “in series” such as the bronchial tree would have profound effects if tissue is injured compared to lung parenchymal tissue (If you damage some, there is plenty more that is able to compensate) - Always concern for spinal cord when radiating the mediastinum *What are side effects you counsel patients on, specifically in thoracic radiation? - Fatigue (usually not debilitating), radiation esophagitis, pericarditis (rare) - Radiation pneumonitis (usually 6-8 weeks, but can be up to one year), presents with cough, shortness of breath; likelihood of this is dependent on duration of treatment, dose of radiation, location A special thank you to our guest, Evan Osmundson, MD, PhD, Associate Professor in the Department of Radiation Oncology and serves as the Medical Director of Radiation Oncology at Vanderbilt University Medical Center in Nashville, TN!Please visit our website (TheFellowOnCall.com) for more information Twitter: @TheFellowOnCallInstagram: @TheFellowOnCallListen in on: Apple Podcast, Spotify, and Google Podcast
references Am J Physiol Regul Integr Comp Physiol2018. 314: R909–R915. Obesity (Silver Spring). 2008 Jun; 16(6): 1284–1288 Front. Immunol., 26 April 2019 Sec. NK and Innate Lymphoid Cell Biology Journal of Biological Chemistry 2018. 293: 2422-2437 --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
Lung cancer does not just happen to people who smoke.Meet Jill Atcheson, a healthy, vibrant young mom who was diagnosed with Stage 4 lung cancer at the age of 37. And guess what? She NEVER smoked a cigarette in her life. Her story is a profound example of what can happen when you partner conventional medicine with a holistic approach. Jill has a phenomenal outlook and that also plays into her health and well-being. Listen in today as I talk with her about that diagnosis, her treatment choices and the biggest surprise of all while she was on this journey!Connect with Jill at Luv Your Life Naturally:https://luvyourlifenaturally.com/Suggested Resource Links:Luv Your Life NaturallyBOOK: Metabolic Approach to Cancer
This week we are joined by ShrapKnel (Curly Castro and PremRock) along with producer Steel Tipped Dove to discuss their new album Metal Lung. You can find Metal Lung and all ShrapKnel related merch here: https://shrapknel.bandcamp.com/album/metal-lung For early access to episodes and exclusive content you can join our patreon: https://www.patreon.com/calloutculturepodcast --- Support this podcast: https://anchor.fm/calloutculture/support
We have a great show for you which will provide all of the answers you have come to expect from The Word on Medicine. On Saturday, we will discuss Lung Transplantation: medical experts and a patient discuss lung transplantation, a life-saving operation. Our expert panelists include Dr. Nilto De Oliveira, Dr. Alan Bentensley, Dr. Samir Sultan, and Lindsay Morris (APNP). You will want to hear the inspirational story from our patient guest and his wife - he received the ultimate gift, the gift of a lung transplant which saved his life!
#RafiFarber: Low #Silver Prices Forcing Drain from #Comex and #LBMA Low silver prices sure don't feel good, but they're hitting the Comex and the LBMA in London much harder than they're hitting the stackers. As of this week, 100 MILLION ounces of silver have been drained from the Comex registry, and silver stockpiles are at a new record low at LBMA in London since statistics began. Meanwhile, the August physical #gold drain rivals the all time record July drain, and could overtake it for a new record by the end of the month. Someone, something, is buying all this silver and gold. It doesn't feel like it yet, but the reinforcements have already arrived. The longer silver stays depressed, the faster these stocks must drain, as the hourglass on the dollar creeps lower and lower. Hang in there silverbacks. Take a breath. Lung capacity is key. To find out more, click to watch the video now! - To get a free 2 week trial to Rafi's 'The End Game Investor Report go to: https://seekingalpha.com/mp/1347-the-end-game-investor/articles - To find out more about Fortuna Silver go to: https://fortunasilver.com/ - To get Arcadia silver videos delivered straight to your email inbox click here: https://arcadiaeconomics.com/email-signup/ - To get on the waiting list for your very own ´Silver Chopper Ben´sterling silver figurine click here: https://arcadiaeconomics.com/get-a-chopper-ben/ - To get your paperback or audio copy of The Big Silver Short go to: https://arcadiaeconomics.com/thebigsilvershort/ - To see the evidence of manipulative behavior in the silver market (as well as how you can send it to your local regulators and Congressional representatives) click here: https://arcadiaeconomics.com/cftc-complaint/ - To sign the petition to ban JP Morgan from having any involvement in the silver industry click here: https://www.ipetitions.com/petition/ban-jp-morgan-from-trading-gold-and-silver - Follow Arcadia Economics on Twitter: https://twitter.com/ArcadiaEconomic - To receive updates about Arcadia option trading events: https://arcadiaeconomics.com/options/ - #silver #silverprice And remember to get outside and have some fun every once in a while!:) (URL0VD)Subscribe to Arcadia Economics on Soundwise
Some leaders are humble and have a high level of tolerance, others stand out for their charisma and social skills and others are recognized for their great commitment and responsibility. But to be a great leader you have to be an effective communicator. However, effective communication doesn't always require the exchange of words. Sometimes, it's best to simply be present, listen and try to establish a better connection. It takes a passionate leader to create that connection, which paves the way for learning and growth. In this episode of Fifth Dimensional Leadership, I interview Matt Abrahams. Matt is a passionate, collaborative, and innovative educator and coach. He teaches Effective Virtual Communication and Essentials of Strategic Communication at Stanford University's Graduate School of Business. In our conversation, Matt talks about how communication creates connections that unlock opportunities to learn, grow, and be challenged. Matt is also Founder and Principal at Think Fast Talk Smart LLC, a presentation and communication skills company based in Silicon Valley that helps people improve their presentation skills. Matt is writing his second book, Think Fast Talk Smart: How to think and speak brilliantly in impromptu situations, and the third edition of his book Speaking Up Without Freaking Out, a book written to help the millions of people who want to present more confidently and convincingly. He also hosts the GSB podcast called Think Fast Talk Smart, and he curates the NoFreakingSpeaking.com website. Matt received his undergraduate degree in psychology from Stanford University, his graduate degree in communication studies from the University of California at Davis, and his secondary education teaching credential from San Francisco State University. Things you will also learn in this episode: What the “Rule of Lung” is and how to manage anxiety How to master “spontaneous speaking” Why “Yes/And” is a helpful framework and mindset How introverted leaders can help organizations The impact of Diversity, Equity & Inclusion on communication. Why feedback is an invitation to problem solve Quotes “We do need to have some level of judgment and evaluation, but we evaluate and judge so much that we actually inhibit ourselves from doing anything.” - Matt Abrahams “‘Yes/And' leads to building opportunity and collaboration; ‘No' shuts that down.” - Matt Abrahams “Our communication follows from our mindset. The mindset we have dictates the way we communicate.” - Matt Abrahams “The things that we can do as coaches, mentors, and friends is focus on the effort and help people realize the improvement that they're making.” - Matt Abrahams “The most important thing you can do in communication is listen.” - Matt Abrahams “Find things in your life that are scary-fun! You get to decide how scary and how fun you want to have, but both of those are good guides.” - Matt Abrahams “Communication is more than just transactional exchange of information, there's a human connection that has to happen.”- Matt Abrahams
Jayne Rees Buxton is an accomplished and award-winning author and journalist. She is the author of The Great Plant Based Con- Why Eating a Plants-Only Diet Won't Improve Your Health or Save the Planet, an excellent piece focused on how plant-based diets can harm your health, how pharma companies and food companies profit from people eating this way, and more!. Book: https://thegreatplantbasedcon.com/ Twitter: https://twitter.com/JayneReesBuxton This episode is brought to you by Optimal Carnivore. Do you struggle to eat organ meat? Optimal Carnivore was created by Carnivores for Carnivores. They created a unique organ complex from grass-fed animals in New Zealand. It includes 9 different organs - Liver, Brain, Heart, Thymus, Kidney, Spleen, Pancreas, Lung etc. Taking 6 capsules is the same as eating an ounce of raw organ meat from the butcher. Get 10% off your order by going to https://amzn.to/3hSXXtu and using the code: carnivore10 at checkout! (currently only shipping within the US) LMNT is offering a free sample pack along with any regular purchase when you use my custom link drinklmnt.com/carnivorecast . The LMNT Sample Pack includes 1 packet of every flavor. This is the perfect offer for 1) anyone who is interested in trying all of our flavors or 2) wants to introduce a friend to LMNT. Go to drinklmnt.com/carnivorecast to claim this awesome deal! What questions would you like answered or who would you like to hear from in the carnivore or research community? Let me know on Twitter, Instagram, and Facebook.
In this episode, we review the high-yield topic of Lung Development from the Embryology section. Follow Medbullets on social media: Facebook: www.facebook.com/medbullets Instagram: www.instagram.com/medbulletsofficial Twitter: www.twitter.com/medbulletsIn this episode --- Send in a voice message: https://anchor.fm/medbulletsstep1/message
Go online to PeerView.com/PUE860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. Gene fusions and other key alterations (NTRK, RET, and others) represent actionable targets in a substantial proportion of patients with solid tumors. Appropriate biomarker testing is crucial to identify all alterations that are treatable with current or investigational targeted therapies. Multikinase tyrosine kinase inhibitors (TKIs) have been used to treat such alterations, but they have limited efficacy. Therefore, next-generation TKIs with greater selectivity have been developed and approved for tumor-agnostic indications (such as NTRK alterations) and for specific tumor types (such as RET alterations in lung and thyroid cancers). These newer therapies have demonstrated impressive efficacy with favorable safety profiles, and their use can significantly improve patient outcomes and quality of life. The tumor-agnostic indications are anticipated to expand further, and novel options are also emerging for patients who have developed resistance to standard RET- and TRK-targeted therapies. In this PeerView educational offering, experts on gene fusion-positive solid tumors provide a cutting-edge update on the role and relevance of gene fusions and other key alterations in solid tumors. These KOLs offer guidance on how to best identify patients with gene alterations and discuss accumulating clinical evidence for the best use of targeted therapies, while also providing practical guidance for optimizing multidisciplinary and interprofessional strategies for biomarker testing and use of targeted therapy across solid tumors harboring NTRK and RET fusions and other actionable alterations. Upon completion of this activity, participants should be better able to: Describe the role of NTRK, RET, ALK, and other key genomic alterations in the oncogenesis of solid tumors, the importance of appropriate biomarker testing to identify patients with these alterations, and clinical evidence supporting the use of matched targeted therapies to optimize patient outcomes; Collaborate with the broader cancer care team to identify patients for biomarker testing, select appropriate tests to capture all relevant genomic alterations, including gene fusions, and interpret testing results to guide treatment selection; Apply the latest evidence and guidelines to individualize targeted therapy for patients with cancers harboring NTRK, RET, ALK, and other targetable genomic alterations; and Educate patients about the role of biomarker testing, risks and benefits of targeted therapies, and importance of selecting optimal therapy based on biomarker testing results and patient needs, values, and preferences.
Tanya Doan, 45, lung cancer, Braintree, with husband, Mark Rudolph, daughter, Rebecca, and Dr. David Jackman, Medical Director for Clinical Pathways, Dana-Farber ● Tanya was diagnosed with 4 EGFR adenocarcinoma of the lower lobe of right lung atthe beginning of 2021. After experiencing migraines, Tanya had an MRI and CT scanwhich showed the cancer.● Her father had been diagnosed with the same cancer the previous year.● EGFR lung cancer commonly affects non-smoking young Asians.● Tanya had surgery to remove two tumors, followed by radiation and immunotherapy.She is still on the immunotherapy and gets an infusion every three months for herbone metastases.● Tanya enjoys reading, exercising with her Peloton, cooking, travelling, and raising herHavanese puppy. She loves spending time with her family, including daughtersRebecca and Zoe.● Tanya feels Dana-Farber is special because every single person who works there --from the people who work in the coffee shop to the radiology techs, MAs and RNs --are kind and friendly.● She says that the physicians, PAs and NPs are phenomenal and that the nutritionistsand social workers have been especially helpful. For her, Dana Farber has become ahome away from home. ● She likes knowing her treatment is on the cutting edge and not having to worryabout researching treatment on her own. Lung cancer facts● Lung cancer is the uncontrolled growth of abnormal cells in one or both lungs.● These abnormal cells do not carry out the functions of normal lung cells and do notdevelop into healthy lung tissue. As they grow, the abnormal cells can form tumorsand interfere with the functioning of the lung, which provides oxygen to the body viathe blood.● Lung cancer is the second most common cancer (not counting skin cancer) in bothmen and women.● According to the American Cancer Society, there will be an estimated 236,740 newcases of lung cancer in the United States for 2022.● Lung cancer is the leading cause of cancer death in the United States, among bothmen and women. Lung cancer claims more lives each year than do colon, prostate,ovarian and breast cancers combined.● Overall, the chance that a man will develop lung cancer in his lifetime is about 1 in15; for a woman, the risk is about 1 in 1.7● People who smoke have the greatest risk of lung cancer, and about 80% of lungcancer deaths are thought to result from smoking, though lung cancer can also occurin people who have never smoked. The risk of lung cancer increases with the lengthof time and number of cigarettes you've smoked.● Lung cancer is divided into primary or secondary lung cancer.-Primary lung cancer starts in the lungs. The cancer cells are abnormal lung cells.-Secondary lung cancer is when people who have cancer travel from another part oftheir body or metastasize to their lungs. This is called secondary lung cancer because thelungs are a secondary site compared to the original primary location of the cancer.Dr. David Jackman● Dr. Jackman is a Senior Physician in the Thoracic Oncology Program at Dana-Farber,where he cares for patients with lung cancer, mesothelioma, and thymoma. He also serves as the Medical Director for Clinical Pathways, helping to create and oversee aweb-based platform in which doctors across the country and the world, can seekcare recommendations for their patients based on the expertise of Dana-Farber'sphysicians and researchers, extending the expertise of Dana-Farber physicians.
This week's guest is someone who we originally followed on YouTube & over the past 7-8 months has become a great friend. Jon Pounders is the owner & founder of one of our favorite channels Now You See TV. He has dedicated the last 15 years of his life to educating himself and others in Biblical, historical, and survival research and training. He's also a host on the Midnight Ride, Breaking Babylon and Pounders Live. Jon has had an amazing transformation, losing over 70 lbs. But today we're gonna go deeper into how far reaching this transformation has been.www.nystv.orghttps://www.youtube.com/c/NowYouSeeTV Our sponsor this week is Optimal Carnivore. Optimal carnivore sources 100% grass-fed organ meats from New Zealand, freeze-drying the organs & encapsulating them into convenient bovine gelatin capsules. Unlike a lot of areas in the US, NZ still has rich soil, lush greenery & one of the cleanest environments on earth. They currently have a Grass Fed Organ Complex that contains 9 different Organs including Beef Liver, Brain, Thymus, Heart, Kidney, Spleen, Pancreas, Lung and Gallbladder, and a Grass Fed Liver product. These products are perfect for people who are traveling or still trying to develop an appreciation for organ meats. Optimal carnivore covers your bases at home or while traveling, and their products are 100% grass-fed and grass-finished and free of hormones, pesticides, antibiotics and GMOs.The mission over at Optimal Carnivore is to make it easy for people to consume the most nutrient-dense foods on the planet. They also plant 1 tree for every product sold which helps the environment! Head to amazon.com/optimalcarnivore and use the code: “vegasave10” to receive 10% off all products!https://www.amazon.com/optimalcarnivoreDiscount code: vegasave10 for 10% off your order.Also sponsored by Regenerative Pastures providing grass-fed meat directly to your door from ranchers who practice regenerative agriculture. This means it's healthier for the environment because of the way the land and animals are managed to sequester carbon, reverse desertification, promote healthy soil biology and in turn create healthier meat for us to consume with higher Omega 3's.They have an incredible selection of grass-fed beef boxes, organ meats and organ jerky that are all regeneratively raised. Supporting Regenerative Pastures directly supports ranchers financially, helps the environment, and ensures high quality, delicious protein for us to eat.https://regenerativepastures.comMake sure to check them out & use FATFUELED to save 30% on your subscription box! Follow us!http://www.instagram.com/fatfueledmomhttp://www.instagram.com/dannyvega.mshttp://www.instagram.com/fatfueledkidsYouTubehttp://www.youtube.com/fatfueledfamilyPlease make sure to SUBSCRIBE and leave us a 5-STAR RATING & REVIEW if you like our content!Please visit our blog:http://www.fatfueled.familyCarnivore Keto Cut:https://carnivoreketocut.com/sales-pagePRODUCT CODES and LINKSAmazon Store - http://www.amazon.com/shop/fatfueledmomOptimal Carnivore: amazon.com/optimalcarnivore Discount code: vegasave10KetoLogic 10% discount code: FATFUELEDFAMKetoLogic KETO 30: http://bit.ly/2EaqQRGKetoLogic BHB gummies: http://bit.ly/2DhgvkHFBOMB 20% discount code: FATFUELEDFAMFBOMB nut butters: http://bit.ly/2PySREs1Up Nutrition Supplements: Use code FFM20 for 20% off your order at https://1upnutrition.comCarnivore Crisps! - http://www.carnivorecrisps.com Code: FFF to save.Spiral Band Fitness: Use code MAURA to save 10% at https://www.spiralbandfitness.comPili Nuts: FATFUELEDMOM saves you 10% at http://www.eatpilinuts.comNeuroroast Coffee: KETOCC saves you 10% at http://www.neuroast.comSelect CBD: https://bit.ly/2AesxgyBeautycounter Safe Non-Toxic Beauty Products: http://www.beautycounter.com/mauravegaSanta Cruz Medicinals: Save $5 with code fatfueledmomFat Fueled Family bundle from eBar Cattle Company:https://ebarcattlecompany.com/collections/packages/products/fat-fueled-family-bundleMake sure to use FATFUELEDFAM to save 10% on your entire order!
Lung cancer specialized testing in NSCLC: What do we do if we biopsy a suspected metastatic lesion?* Immunohistochemistry (IHC): **Confirm if it is metastatic NSCLC **Confirms the histology of the NSCLC (such as adenocarcinoma vs. squamous cell)**Used to determine the type of chemotherapy that can be administered for treatment *PDL1 testing: **PDL1 is a protein expressed by certain cancer cells allowing them to evade the immune system (“fake mustache analogy”).**Also confirmed by IHC**This protein is targetable!**Often measured as:***Total protein expression (TPS): The number of positive tumor cells divided by the total number of viable tumor cells multiplied by 100%***Composite protein expression (CPS): The number of positive tumor cells, lymphocytes and macrophages, divided by the total number of viable tumor cells multiplied by 100%*Molecular testing: **We discuss this in detail in Episode 005**Genetic information from the tissue sample**Always better to get sample from soft tissue than from bone**Why is this important?***To be able to identify “driver mutations”****What is it? Important mutations that may be “driving” oncogenesis****Many of these have drugs that directly target these mutationsPrognostic vs. predictive biomarkers:*Prognostic biomarkers: Mutations or changes that give information about the cancer's overall outcome regardless of therapy*Predictive biomarkers: Mutations that provide information about how a cancer may respond to a particular drug Cell-free DNA (AKA “liquid biopsy”):*Special tests that can detect microscopic amounts of cancer cell DNA within the patient's blood which may also be used to find prognostic/predictive biomarkers*Ongoing studies to see if this can be used to find relapse of diseasePlease visit our website (TheFellowOnCall.com) for more information Twitter: @TheFellowOnCallInstagram: @TheFellowOnCallListen in on: Apple Podcast, Spotify, and Google Podcast
Dr Steve, Dr Scott, and Tacie discuss: 1. Selective Attention 2. Acupuncture and pre-diabetes 3. Muscle spasms with injections 4. Championship wrestling 5. Benign Vertigo and The Epley Maneuver 6. Ol' Starfighter From the Past calls in 7. Covid antibodies and autoimmune disorders Radio frequency treatment for stress incontinence Here's the video we discussed: https://youtu.be/vJG698U2Mvo Please visit: stuff.doctorsteve.com (for all your online shopping needs!) simplyherbals.net (now with NO !vermect!n!) (JUST KIDDING, Podcast app overlords! Sheesh!) roadie.doctorsteve.com (the greatest gift for a guitarist or bassist! The robotic tuner!) And our sponsor: BetterHelp.com/medicine (we all need a little help right now!) Also don't forget: Cameo.com/weirdmedicine (Book your old pal right now while he's still cheap! "FLUID!") noom.doctorsteve.com (the link still works! Lose weight now before swimsuit season is over!) CHECK US OUT ON PATREON! ALL NEW CONTENT! Robert Kelly, Mark Normand, mystery guests! Stuff you will never hear on the main show ;-) Learn more about your ad choices. Visit podcastchoices.com/adchoices
Dr. Sarah Zaldivar, @dr.sarah.zaldivar, is a Nutrition Professor at Miami Dade College, holds a PhD in Exercise Physiology and Nutrition, and has an incredible YouTube channel with amazing interviews with carnivores and more! Instagram: https://www.instagram.com/dr.sarah.zaldivar YouTube: https://www.youtube.com/channel/UCBXm-oCTN-dJdbD65gK5lEQ This episode is brought to you by Optimal Carnivore. Do you struggle to eat organ meat? Optimal Carnivore was created by Carnivores for Carnivores. They created a unique organ complex from grass-fed animals in New Zealand. It includes 9 different organs - Liver, Brain, Heart, Thymus, Kidney, Spleen, Pancreas, Lung etc. Taking 6 capsules is the same as eating an ounce of raw organ meat from the butcher. Get 10% off your order by going to https://amzn.to/3hSXXtu and using the code: carnivore10 at checkout! (currently only shipping within the US) LMNT is offering a free sample pack along with any regular purchase when you use my custom link drinklmnt.com/carnivorecast . The LMNT Sample Pack includes 1 packet of every flavor. This is the perfect offer for 1) anyone who is interested in trying all of our flavors or 2) wants to introduce a friend to LMNT. Go to drinklmnt.com/carnivorecast to claim this awesome deal! What questions would you like answered or who would you like to hear from in the carnivore or research community? Let me know on Twitter, Instagram, and Facebook.
In Episode #220, Dr MeiLan Han joins me to discuss the lungs and respiratory system. Despite being an incredibly important factor of our overall health, the respiratory system is often overlooked. Most people's knowledge is surface level, and we aren't educated on the importance of the lungs or how to best support respiratory health. Dr MeiLan Han joins me in this episode to explain what the respiratory system is, how it works, and what we can do to optimise it. In this episode, Dr Han establishes what the respiratory system is and how it works. We discuss the prevalence of lung conditions, Covid-19 and its impact on the respiratory system, and air quality. We also discuss healthy habits for pregnancy, the effects of smoking and vaping on lung health, diet, and how to reduce exposure to toxic compounds. Specifically, we cover: Intro [0:00] Breathing Lessons: The Book [2:09] Meilan's Story [5:59] Importance of Lung Awareness [11:07] Lung Tests [24:25] Impact of Covid [29:57] How the Lungs Work [33:32] Childhood Lung Health [44:52] Air Quality [53:55] Cleansing the Lungs [1:15:20] COPD [1:19:47] Final Thoughts [1:27:32] Outro [1:29:35] If you are interested in learning more about lung health, Dr Han's book is the perfect resource. You can find her book, Breathing Lessons: A Doctor's Guide to Lung Health, here. You can also connect with Dr Han on Instagram, Twitter, Facebook, YouTube, and LinkedIn. Her website, www.drmeilanhan.com/, contains more information and trusted resources. The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. Make sure to head to theproof.com/podcast for the full show notes. Enjoy, friends. Simon Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. Simon Hill, Msc, Bsc (Hons) Creator of Theproof.com and host of The Proof with Simon Hill Author of The Proof is in the Plants Watch the episodes on YouTube, or Listen on Apple/Spotify Connect with me on Instagram, Twitter and Facebook Download my complimentary two week meal plan and plant performance Learn more about your ad choices. Visit megaphone.fm/adchoices