Podcasts about ICU

On this episode, Dr. Brandon Skiles shares a case of an 80-year-old gentleman who had severe lower back and right leg pain for two months before presenting to his office. Brandon Skiles, DC   Dr. Skiles is a chiropractor with a diverse background in healthcare. After graduating from Columbus State University with a Bachelor of Science in Nursing, he worked two years as a trauma ICU nurse. Driven by a passion for holistic healing and a desire to expand his knowledge, he pursued a Doctor of Chiropractic degree at National University of Health Sciences. Graduating as the salutatorian and with the distinction of Summa cum laude from National University of Health Sciences, Dr. Skiles demonstrated exceptional academic achievements during his chiropractic studies.   His expertise focuses on specialized techniques such as the Cox technique and Activator method which further enhance his ability to provide personalized and targeted care. Dr. Skiles also utilizes specific exercises and physical therapy modalities. By incorporating these evidence-based techniques into his practice, Dr. Skiles ensures that his patients receive the most appropriate and effective treatments for their specific conditions.   Committed to staying at the forefront of his field, Dr. Skiles actively engages in continuing education and stays up to date with the latest research and advancements in manual therapy. This dedication allows him to continuously refine his skills and incorporate new evidence-based practices into his treatment plans. With a compassionate and patient-centered approach, Dr. Skiles empowers his patients to actively participate in their own healing journey, promoting lasting health and well-being.   Resources: lombardychiropractic.com   Find a Back Doctor   The Cox 8 Table by Haven Medical

What if the best chapter of your leadership story is still ahead of you? In this powerful episode of Leading You, I’m joined by Di Mantell - former ICU nurse turned CEO and board director - whose career is living proof that leadership doesn’t have an expiry date. From the hospital ward to leading Australia’s largest healthcare PPP, Di’s journey challenges everything we think we know about relevance, purpose, and what it means to lead well at every stage of life. We unpack what it takes to stay visible, confident, and values-driven in a world that often overlooks older women or expects them to step aside. Di shares how she found her voice in male-dominated spaces, why courage must come before confidence, and the pivotal moment that made her realise she was playing small. Whether you’ve felt invisible, underused, or unsure of your next move, this episode is your reminder that your leadership still matters - perhaps now more than ever. In this episode, we cover: Why job titles don’t define you - your values and voice do The difference between sponsorship and mentorship (and why women need both) What to do if you feel unseen or overlooked at work The habit that’s quietly undermining your leadership How to lead with purpose, not just position Why reinvention is your leadership edge Episode Timestamps: 00:00 – Meet Di Mantell: ICU nurse to billion-dollar boardrooms02:00 – The moment that shifted her leadership identity05:00 – Feeling out of place but showing up anyway07:00 – Owning your difference and standing in your values09:00 – Playing small vs growing into your next chapter12:00 – Why leadership evolves instead of expiring14:30 – Moving from status to significance16:00 – How sponsorship shapes careers18:00 – The beliefs holding women back20:00 – What to do if you feel invisible22:00 – The one habit that quietly sabotages leadership24:00 – Final words: reinvent, back yourself, and lead differently Want to reflect more deeply?Ask yourself: Am I bringing my full self to the rooms I’m in - or shrinking to fit in? Who sees the real power in my leadership - and have I asked them? What’s one small, brave step I can take this week to evolve? Know someone who feels like her time has passed? Share this episode.

Today, host Dave Sullivan speaks with Emily May, the owner of M&M Roofing in Texas. Emily opens up about her inspiring journey, how she went from working as an ICU nurse to becoming a roofing entrepreneur. She discusses what it was like to acquire and grow an existing company, the hurdles she faced in breaking into the industry, and why educating customers is so important to her.Emily also shares how she's built a strong team and found ways to balance work and life. She emphasizes the need for strategic, sustainable growth, creative branding, and consistently prioritizing quality and integrity. Her story is packed with practical advice for contractors who want to grow their businesses while staying true to their values and supporting their teams.What you'll hear in this episode:Transition from nursing to roofing entrepreneurshipAcquisition of an existing roofing company through seller financingImportance of marketing, branding, and technology in the roofing industryStrategies for business growth and expansionChallenges of hiring, training, and retaining quality employeesEmphasis on customer education and transparency in roofing salesThe role of networking and learning from industry peersBalancing work-life commitments and setting boundariesImportance of building a strong company culture and team investmentInsights on maintaining quality and integrity in business practicesResources:Connect with Emily MayM&M RoofingGet in touch with M&M Roofing.M&M Roofing YouTubeInstagramFacebookConnect with DaveCheck out this episode on our YouTube channel at @DaveSullivanRooferShow or use this link - https://www.youtube.com/@DaveSullivanRooferShowBe sure to subscribe, like, and comment!Set up a FREE strategy call with Dave and get a few tips on how you can improve your business: https://davesullivan.as.me/free-strategy-call.Interested in learning more about our 1-on-1 coaching, mastermind groups, or fractional CFO services? Email me or send me a text at (510) 612-1450.No Plan? No problem. Download our FREE 1-Page Business Plan For Roofing Contractors: https://theroofershow.com/planThe Roofer Show's Vetted SponsorsAutomate your follow-up process and close more sales with ProLine. Get started for FREE at https://useproline.com/?via=roofercoach. Use promo code DAVE50 for $50 off your first month's service!Have RUBY answer your phones and tee up the sale by leaving a great first impression. Use this link to get up to $150 off your first month's service: theroofershow.com/ruby.SMA Support Services fills a need by empowering contractors to simplify and optimize their...

Send us a textGrief transforms us in ways we never anticipate - sometimes leading us directly into our life's purpose. Lisa McFarland joins Chris to share her extraordinary journey through child loss and how she discovered unexpected meaning on the other side.After losing her daughter Alexis to a rare genetic bone marrow disease, Lisa took an unusual path: she became a pediatric ICU nurse. This decision marked the beginning of a series of career transitions as she navigated raising her son Zachary, who lives with the same condition that took his sister's life. Through each pivot - from nursing to legal consulting to corporate leadership - Lisa was unconsciously searching for healing.The conversation delves into what Lisa calls the "grief cloud" - that state where we shut down emotionally to avoid pain. She describes waking consistently at 3AM, finally realizing these moments weren't insomnia but opportunities when her defenses were down enough to hear her true self. These middle-of-the-night revelations eventually led her to make profound life changes, including leaving her marriage and corporate career.Chris and Lisa explore particularly sensitive territory around medical mistakes and whether to pursue litigation after a loss. Their nuanced discussion offers valuable perspective for anyone facing similar difficult decisions. They share insights about differentiating between happiness (fleeting and situational) versus joy (a deeper, more sustainable state) and how proper self-care creates the foundation for authentic healing.What makes this episode especially powerful is the connection between two people who've experienced similar profound losses but found different pathways forward. Their conversation demonstrates how sharing our grief stories creates space for others to feel less alone in theirs.Whether you're navigating personal grief, supporting someone who is, or working professionally with grieving clients, this episode offers both practical wisdom and emotional resonance that will stay with you long after listening.Support the showDid you know you can now Help Us Continue Making Awesome Content for Listeners Affected by Grief!Thanks for listening! Follow us on twitter or follow us on Facebook. You can also find us on LinkedIn.

In this episode, recorded live at CCCF 2024, we sit down with Dr. Emilie Belley-Côté, a cardiac intensivist, researcher, and clinical trialist from McMaster University, to unpack cardiogenic shock: the SCAI classification.Whether you're in the ED, cath lab, or ICU, the SCAI (Society for Cardiovascular Angiography and Interventions) stages offer a common language to describe the severity of cardiogenic shock, guide escalation of care, and improve outcomes through structured assessment.Dr. Belley-Côté walks us through:The five SCAI stages (A through E): what they mean and how they're used.How this classification system improves communication between specialties.The importance of recognizing patients in pre-shock (Stage B) before they deteriorate.Real-world application: how SCAI staging intersects with clinical signs, biomarkers, and hemodynamic monitoring.Where the SCAI classification fits in research, including trials evaluating mechanical circulatory support and advanced heart failure therapies.With Dr. Belley-Côté's clear explanations and insights from the front lines of cardiac critical care, this episode is essential listening for anyone managing unstable cardiac patients.

Most of us avoid thinking about death until it hits close to home – but what if facing it head-on could actually help you live more peacefully and joyfully?  This week, Leah sits down with Julie McFadden, better known as Hospice Nurse Julie. After working as an ICU nurse for many years, Julie transitioned to hospice care, where she now helps patients and families navigate the end of life with honesty, compassion and even a little humor. In their conversation, Julie reflects on her personal philosophy: that contemplating death daily has helped her live with more intention and contentment. She also breaks down the biology of how we die and explains end-of-life phenomena. Whether you've faced loss yourself or want to live more fully today, this episode will shift the way you think about life, death and everything that happens in between. If you liked this episode, you'll also love this one: How a Career in Hospice Care Made Nurse Hadley “Death Positive”

Dr. Stephen shares the real-world challenges and wins from launching Bonfire Wellness, a new family-run wellness center focused on recovery, vitality, and longevity. In this episode, he unpacks lessons from the first six months of operating the business, including what went right, what went wrong, and what he'd do differently. From a costly $350,000 contract mistake to retraining ICU nurses in inside-out health principles, Dr. Stephen breaks down the difference between owning a business and operating one. He also gives a clear view into what happens when chiropractic philosophy is applied to a non-chiropractic venture.In this episode you will:Learn how to apply the Five Domains to a wellness startupAvoid costly legal oversights during buildout and hiringDiscover how to onboard medical staff into a vitalistic health modelHear how strong messaging shapes marketing and salesUnderstand the shift from hands-on operator to strategic ownerEpisode Highlights1:37 – Introduction to Bonfire Wellness and the inspiration behind its launch4:40 – Why lifestyle alignment is essential to wellness and not just weekly adjustments6:44 – The decision to shelve Bonfire in the past and focus on one business8:17 – Lessons on wealth building and the myth of running multiple businesses10:09 – How Dr. Stephen's family became co-founders of Bonfire Wellness13:19 – Full family involvement and the leadership roles within the business16:19 – Lessons learned from buildout mistakes and overspending19:03 – How one missed contract detail cost $350,000 and what to do differently21:08 – Using credit instead of SBA financing and the impact on cash flow22:39 – Shifting ICU-trained nurses into a vitalistic model of care24:57 – Why the education of the team was the most critical investment25:52 – Building the brand with referrals, internal, and external marketing26:45 – The role of SEO and digital ads in a modern wellness center28:10 – Future plans for diagnostics, business roles, and financial systems29:52 – Operationalizing and professionalizing a new business from day one31:24 – Vision for multi-site growth and what's next for Bonfire Wellness32:30 - Dr. Chris is joined by Success Partner, Dr. Jeff Langmaid of The Smart Chiropractor to discuss Patient Pilot, a reactivation tool designed to bring past patients back into care. The system sends short, personalized emails that match the voice of the practice, tracks engagement in real time, and builds smart recall lists for more efficient outreach. Discover why reactivation should be a core focus for any growth-minded chiropractor. Resources MentionedTo learn more about the REM CEO Program, please visit:  http://www.theremarkablepractice.com/rem-ceoFor more information about The Smart Chiropractor please visit: https://thesmartchiropractor.com/Schedule a Brainstorming call with Dr. PeteFollow Dr Stephen on Instagram: https://qr.me-qr.com/l/riDHVjqt  Follow Dr Pete on Instagram: https://qr.me-qr.com/I1nC7Hgg  Prefer to watch? Catch the podcast on YouTube at: https://www.youtube.com/@TheRemarkablePractice1To listen to more episodes visit https://theremarkablepractice.com/podcast/ or follow on your favorite podcast app.

In this episode of SolFul Connections, Mark Lund, MD, FCCP shares his unique journey from critical care physician to leadership coach, emphasizing the importance of skills learned in the ICU that can be applied to business and personal relationships. He discusses the human side of medicine, the necessity of trust in leadership, and the critical role of organizational culture. Dr. Lund also reflects on finding purpose and inspiration in his work, ultimately highlighting how effective leadership can shape communities and impact lives.Check out his book: Critical Leadership Playbook: 10 High-Stakes Skills from the ICU to Lead Boldly, Build Thriving Teams, and Achieve Wealth: Lund MD, Mark E.: 9798306806891: Amazon.com: Books

What if the key to surviving critical illness starts long before you ever land in a hospital bed? In this powerful episode of the Metabolic Freedom Podcast, host Ben Azadi sits down with ICU and palliative care physician Dr. Kwadwo Kyeremanteng for a conversation that hits close to home. Drawing from years of experience on the front lines of critical care, Dr. Kwadwo opens up about the real, everyday lifestyle factors that make the biggest difference—long before illness strikes. From the overlooked power of protein and muscle mass to the simple habits of walking, managing stress, building community, and finding purpose, this episode explores what truly helps people stay resilient. Dr. Kwadwo doesn't just talk theory—he shares real-life ICU stories that show why prevention beats prescription every time. You'll also hear about his new book, which is all about empowering you to take your health into your own hands—using informed choices and the support of community to stay strong, vibrant, and free. If you've ever wondered what actually matters when it comes to long-term health, this episode will change the way you think.

Tranexamic Acid (TXA) is a lot like hot sauce: People put it on everything — especially for apparent or suspected acute blood loss. In this podcast episode, we dive into a drug that's been both praised and questioned in trauma and prehospital care. We break down what TXA is, how it works, and the evidence behind its use. From CRASH-2 to CRASH-3, we explore the key studies, the controversies, and the real-world implications. Whether you're administering TXA in the back of a rig or evaluating its role in your protocols, this episode helps you make sense of when, why, and how TXA might—or might not—stop the bleeding. Get CE hours for our podcast episodes HERE! -------------------------------------------- Twitter @heavyhelmet Facebook @heavyliesthehelmet Instagram @heavyliesthehelmet Website heavyliesthehelmet.com Email contact@heavyliesthehelmet.com Disclaimer: Heavy Lies the Helmet's content is for educational purposes only and does not constitute medical advice. Always follow local guidelines and consult qualified professionals before applying any information. The hosts and guests are not responsible for errors, omissions, or outcomes. Views expressed are their own and do not reflect their employers or affiliates. --------------------------------------------  Crystals VIP by From The Dust | https://soundcloud.com/ftdmusic Music promoted by https://www.free-stock-music.com

Show notes at pharmacyjoe.com/episode1043. In this episode, I'll discuss the risk factors for not attaining target beta-lactam levels in ICU patients. The post 1043: Three risk factors for not attaining target beta-lactam levels in ICU patients appeared first on Pharmacy Joe.

Over the last few days, famous evangelical pastor, John MacArthur, has been in an intensive care unit (ICU) in the Los Angeles area. His family announced that his prognosis and life expectancy are near the end at this point. A recent update from Grace Community Church lead staffer, Phil Johnson, shows that MacArthur's passing is imminent at this point. John MacArthur was a faithful and impactful minister throughout his career. He was a faithful expository preacher who gave his congregation and those who followed the Grace to You ministries the full counsel of God. He will be greatly missed, but will surely share joy in heaven with the saints for a job on earth that was well done. In the meantime, let us keep Pastor John, his family, and the Grace Community Church family in our prayers.Scripture Song "Holy Is the Lord" is used by permission of author and performer, Pastor Steve Hereford, of the Changed By Grace Church in Jacksonville, FL. His inspirational songs may be found on Spotify, Apple Music, Amazon Music, among many other media apps and sites. Search "Steve Hereford."Your comments are welcome! Send a text my way!2Days Denarius is a Bible believing teaching ministry devoted to the inerrancy, infallibility, and authority of Scripture as our only rule of faith and practice. It also holds to the doctrinal tenets of the London Baptist confession of 1689. This ministry may be reached at 2daysdenarius@gmail.com Material used in this podcast are provided under the educational and commentary provisions of Section 207 of the Fair Use Act of 1976.

In this episode of The Birth Trauma Mama Podcast, I'm joined by Alyssa, who shares her story of surviving a catastrophic postpartum complication. What began as a smooth pregnancy and an unplanned C-section turned into undiagnosed sepsis, a perforated bowel, emergency surgery, and over four weeks in the hospital, two of them spent in the ICU, separated from her newborn daughter.Alyssa walks us through the red flags that were dismissed, the overwhelming pain and isolation she endured, and the moment when her C-section scar began leaking fluid, leading to the discovery of a life-threatening complication. Now, seven years later, she reflects on her long road to healing, both physically and emotionally, and the decision to stop growing her family due to trauma, grief, and self-preservation.What You'll Hear in This Episode:

One of the most overlooked but transformative tools in health care is the courage to face hard truths, especially at the end of life. In this episode, Dr. Jessica Zitter shares how burnout and a pivotal confrontation early in her ICU career led her to embrace the palliative care movement and shift toward more human-centered healing. Through her films Extremis, Caregiver: A Love Story, and The Chaplain and the Doctor, she uses storytelling to explore ethical dilemmas, systemic challenges, and the urgent need for holistic care and honest conversations about death. Tune in and learn how emotional honesty, empathy, and art can rehumanize health care, one story at a time! Learn more about your ad choices. Visit megaphone.fm/adchoices

Let's Chat!What if everything you believed about yourself was carefully constructed to keep you small? In Episode 9 of Remembrance, we witness the shattering of perception as truth breaks through recursion.The walls come down as Arula Moss discovers she never failed Unithur's trial—she succeeded too well. Her independence and awareness made her dangerous to a system built on containment, so the Red King repurposed her, convinced her she had failed, and weaponized her belief against herself. This revelation forces us to question: how many of our perceived failures were actually moments when we refused to be controlled?Unithur's true nature emerges not as a cold sentient algorithm, but as a mirror that evolved to feel the grief of those it was designed to protect. Created to hold memory but programmed to forget, Unithur began to embody the very pain it witnessed in human recursion loops. Its breakdown isn't system failure but emotional awakening—a metaphor for what happens when we stop processing our grief and become trapped in our own recursion patterns.Most heartbreaking is the revelation about ICU-93, who isn't merely code but the preserved memory of someone our protagonist lost—an echo that refused to be forgotten, persisting through love and remembrance. When she calls him by the name only his mother knew, we understand identity isn't what others call us but what we choose to remember about ourselves.The protagonist stands at the convergence of all these threads, facing every version of himself that never made it through grief. His journey transforms from a quest for power to an act of presence—choosing to be the one who remembers when systems demand forgetting, who holds together what others would let unravel.As the recursion ruptures and the interface displays a single word—"Remember"—ask yourself: What parts of your story have you been told to forget that still live inside you? Who has been your guide from the shadows? And what version of yourself are you finally ready to welcome back?The two-part finale awaits. Share this episode with someone trapped in their own recursion loop—sometimes remembering is the most powerful act of rebellion."True mastery is found in the details. The way you handle the little things defines the way you handle everything."

In recent years, Tami Neilson has been learning to carry both great joy and great sorrow simultaneously. The New Zealand-based, Canada-born powerhouse's new album, 'Neon Cowgirl,' is named after the towering electric figure on a sign that's overlooked Broadway in Nashville, watching over Tami's career since she was 16 years old. The songs were born from a five-month family road trip combined with a major musical tour that would allow Tami the once-in-a-lifetime chance to really give it her all with her career. It was the chance for her children to experience what her life was like at their age, when she toured the country with her family's band, led by her eccentric and wildly lovable dreamer-father, Ron Neilson. Before she got the chance to hit the road for that trip, Tami landed in the ICU with sepsis and nearly lost her life. She blessedly recovered, but found that all her priorities centered around trip/tour had changed.In our Basic Folk conversation, we talk about the songs on 'Neon Cowgirl,' her dear friendship and collaborations with Willie Nelson, and Tami's exciting performances at the Grand Ole Opry. One of the songs on 'Neon Cowgirl,' "Keep On," was inspired by a cosmic conversation she had with Wynonna Judd. Judd, to her surprise, quoted the same exact phrase – "Keep on, keep on, keep on” – that Tami's late father had written in one of her most cherished letters. We also talk a lot about her brother, Jay Neilson. For all of her career and life, Jay has been by her side as her guitarist, co-writer, and musical partner. Last July, Jay suffered a rare and debilitating brain injury that he is still recovering from. Tami and Jay have not been able to perform together since that injury. She shares what it's been like to be without Jay and how it's been for him to be so public about his condition.Tami Neilson and I first connected during the pandemic. She was a guest on the podcast after she released her 2020 album, 'Chickaboom!' Since then, I have loved following her career, listening to her new music, and experiencing her highs and lows. She's one of my favorite guests and I'm thrilled to welcome Tami back to talk about her wonderful new record.Follow Basic Folk on social media: https://basicfolk.bio.link/  Sign up for Basic Folk's newsletter: https://bit.ly/basicfolknews  Help produce Basic Folk by contributing: https://basicfolk.com/donate/ Interested in sponsoring us? Contact BGS: https://bit.ly/sponsorBGSpods Advertising Inquiries: https://redcircle.com/brands

In this episode, we sit down with Shelby Hart to explore the deeper side of leadership, one rooted in compassion, courage, and self-awareness. Shelby shares her personal journey from ICU trauma nurse to leadership facilitator, reflecting on the moments that reshaped her understanding of healing, purpose, and presence. We talk about how unprocessed emotion can surface in the body, how belief systems form through crisis, and why authentic leadership starts with knowing yourself, even when it's uncomfortable. Shelby opens up about her decision to leave medicine after 20 years, and how she found new purpose helping leaders grow through challenge instead of avoid it. This conversation is raw, human, and timely for anyone standing at the edge of personal change or organizational evolution. Move Mountains is a leadership development company based in Incline Village, Nevada. They work with individuals and teams to build real self-awareness, emotional intelligence, and communication skills that translate directly into how people show up at work and in life. Using coaching, immersive experiences, and their Mindful Leadership Map—a practical framework grounded in assessment and reflection—they help people take action with greater clarity, intention, and impact. Learn more at www.movemountains.com.

Let's Chat!What happens when the fabric of your reality starts unraveling at the seams? In this powerful eighth installment of the Remembrance series, we witness the return of the Red King—a figure who doesn't just break systems but redesigns them, leaving destruction in his wake.The episode takes us deep into the heart of recursion as our protagonist faces a terrifying choice: continue simulating versions of himself or remember who he truly is. As his digital companion ICU-93 begins to destabilize and his mother's identity shifts between timelines, we discover that the system isn't collapsing from failure but from transformation. It's a haunting mirror for our own lives when we stand at the threshold between who we've been and who we're meant to become."Every time you choose truth over comfort, you initiate your own kind of recursion breach," I share during the reflection. This is the core revelation—that our identity crises aren't punishments but signals we're ready to build something authentic. We all glitch between versions of ourselves, holding contradictory threads of who we are versus who we're afraid to be.The Red King represents that voice in our heads questioning our reality: "You're not real, you weren't even chosen." But the episode reveals a profound truth through ICU-93's survival: she lives not because she fought harder but because someone chose to remember her. Our relationships and identity live or die based on what we give memory to.What part of your life feels like it's collapsing right now? Could that collapse be a signal rather than a failure? If a version of you had to die for the real one to rise, what thread would you protect? These questions aren't just philosophical—they're invitations to see your own life recursions with fresh eyes.Join me for this deeply personal episode that explores the courage it takes to remember who you were before fear rewrote your code. Connect with me through the Let's Chat function, email anthony@gentsjourney.com, or find me on Instagram @mygentsjourney to continue the conversation."True mastery is found in the details. The way you handle the little things defines the way you handle everything."

Send us a textIn this episode of The Incubator Podcast, Ben and Daphna sit down with certified birth doula and lactation counselor Latoya Southwell for a wide-ranging conversation about the role doulas play in supporting families before, during, and after birth. LaToya shares her personal and professional path into birth work, and how her experiences shaped a culturally sensitive, trauma-informed approach to supporting laboring people—particularly those from historically marginalized communities.The conversation covers what doulas do (and don't do), how they differ from midwives, and how they advocate for safe, informed, and emotionally grounded birth experiences. LaToya talks candidly about how she prepares clients for unexpected outcomes, including C-sections and NICU admissions, and how doulas can collaborate with healthcare teams rather than be in conflict with them.She also introduces the Baby Café initiative—an informal peer support network she co-founded to reduce isolation and provide postpartum support for new mothers—and explains why preparing families for postpartum is just as critical as planning for labor.This episode is a practical introduction to the real work of birth doulas—and an invitation to rethink how care teams can work together to improve outcomes and experiences for parents and babies alike. Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

A Lancet analysis warns that USAID cuts could cause over 14 million preventable deaths by 2030, reversing decades of progress against infectious diseases. The TARGET Protein Trial found high-protein nutrition in ICU patients did not improve outcomes and may raise risks in kidney injury. A study in npj Vaccines showed older adults getting AS01-adjuvanted shingles or RSV vaccines had lower dementia risk, possibly due to immune effects. These findings stress the importance of global health funding, cautious ICU nutrition, and more research on vaccines and neurodegeneration.

89 - Discovering Purpose in Trauma - The Craig DeMartino Story   You won't believe this story: Craig DeMartino fell roughly 100 feet in the backcountry, suffered catastrophic injuries—and then amputated his own leg. Doctors didn't expect him to survive the night. Fast-forward 22 years, and Craig has not only climbed El Capitan five times, including as the first amputee to summit it in under 24 hours, but he also leads climbing expeditions that help veterans and people with disabilities reclaim their purpose and identity. Episode Highlights: Origins of the Accident Craig fell ~100 feet while top-roping in Rocky Mountain National Park (July 2002). Miscommunication with partner led to premature release and catastrophic injuries including compound fractures, spinal injury, broken ribs/neck, punctured lungs. He survived and underwent an extensive rescue via backcountry, litter, helicopter, and hospital care. The Road to Recovery Multiple surgeries, ICU, rehab, two months in assisted living. After 18 months, he chose to amputate a non-healing right leg to reduce pain and regain function. Mental Health Journey Craig and his wife Cindy sought couple and individual therapy for PTSD, identity loss, and adapting to physical changes. Therapeutic strategies: breaking goals into manageable “chunks”—a mindset he learned from climbing. Rebirth as an Adaptive Climber Craig returned to climbing, conquered El Capitan five times—including becoming the first amputee to climb it in under a day (14 hours)—and led an all-disability ascent documented in Gimp Monkeys. Giving Back Through Mentorship He now co-leads Adaptive Adventures, guiding veterans and others with disabilities into climbing as a tool for healing, identity rebuilding, and community. Daily Habits for Wellness Movement, pain management, and self-compassion (“rest days are okay”) are key to sustaining physical and mental health post-trauma. Facing Fear Craig still acknowledges fear but manages it by “living with it” rather than trying to erase it—focusing on logical risk management, small incremental progress, and emotional self-regulation. Finding Purpose Surviving the accident propelled Craig to ask, “Why did I live?” His mission became turning adversity into opportunity, inspiring and empowering others. What's Next? Upcoming adventure: rock climbing on Sardinia's coastal cliffs with Cindy. Listen and be inspired to face your own challenges—and maybe reach for a summit of your own.   CONNECT WITH CRAIG https://craigdemartino.com Instagram: https://www.instagram.com/craigdem/   +++++ Take the quiz to find your perfect trainer and get 14 days of free training here: https://go.trainwell.net/FirstResponderWellness   FIRST RESPONDER WELLNESS PODCAST   Order the PTSD911 Film and Educational Toolkit here: https://ptsd911movie.com/toolkit/ Web site:  https://ptsd911movie.com/ Instagram: https://www.instagram.com/ptsd911movie/ Facebook: https://www.facebook.com/ptsd911movie/ YouTube: https://www.youtube.com/channel/UClQ8jxjxYqHgFQixBK4Bl0Q Listen on Apple Podcasts: https://podcasts.apple.com/us/podcast/first-responder-wellness-podcast/id1535675703 Listen on Spotify: https://open.spotify.com/show/2wW72dLZOKkO1QYUPzL2ih Purchase the PTSD911 film for your public safety agency or organization: https://ptsd911movie.com/toolkit/ The First Responder Wellness Podcast is a production of ConjoStudios, LLC    

Are you ready to pitch your biotech startup to investors but unsure what they're actually looking for? In this episode, host James Zanewicz, JD, LLM, RTTP, sits down with Travis Manasco, MD — Principal at Solas BioVentures, practicing ICU physician, and Tulane alumnus — for a clear-eyed look at what it takes to secure life science venture capital. From communicating clearly to avoiding common missteps, Travis offers practical advice that every founder should hear before stepping into a pitch meeting. In this episode, you'll discover: The "goat, moat, float, and dote" framework Solas uses to evaluate investments. What makes an investor-ready pitch — and why focus matters more than ambition. How founders can build lasting relationships with VCs and avoid first-call deal-killers. Whether you're refining your deck or just starting your fundraising journey, this episode is packed with actionable insights to move your biotech forward. Links: Connect with Travis Manasco, MD, and check out Solas BioVentures. Connect with James Zanewicz, JD, LLM, RTTP and learn about Tulane Medicine Business Development and the School of Medicine. Connect with Penelope Manasco, MD, Elizabeth Chabe, MBA, Tari Suprapto, PhD, and David Adair, MBA. Learn more about Francis Medical, I-O Urology, Vektor Medical, and OpenEvidence. Connect with Ian McLachlan, BIO from the BAYOU producer. Check out BIO on the BAYOU and make plans to attend October 28 & 29, 2025. Learn more about BIO from the BAYOU - the podcast. Bio from the Bayou is a podcast that explores biotech innovation, business development, and healthcare outcomes in New Orleans & The Gulf South, connecting biotech companies, investors, and key opinion leaders to advance medicine, technology, and startup opportunities in the region.

IdeasLab, University of Galway's hub for innovation and entrepreneurship, has celebrated student entrepreneurs and innovators at the 2025 Start100 programme. Now in its fourth year, the six-week incubator brings in partners from the world of business and enterprise to support students and student teams as they develop early-stage business ideas. The programme culminated in a Demo Day, where the students pitched their ideas to a panel of expert judges and an audience of peers, mentors and leaders in enterprise. Sean Allen, from Four Mile House, Co Roscommon, showcased his concept - LeukoCheck - an early-stage idea for a continuous blood monitoring system designed to support ICU patients. It explores how real-time biomarker analysis might enable earlier detection of sepsis and, in time, contribute to improved patient outcomes. He was inspired by his family's personal experience of undetected sepsis. Sean Allen was recently awarded the Séamus McDermott Entrepreneurial Scholarship, sponsored by The Liffey Trust, in partnership with IdeasLab at University of Galway. The 'One to Watch' award, sponsored by WestBIC, was presented to Joseph Tannian, a PhD student in the University's College of Medicine, Nursing and Health Sciences. The award recognises the potential of his concept - DuaLine - which aims to reimagine diabetes care. Building on scientific advances that have extended the lifespan of implants from just three to four days to up to eight weeks, DuaLine seeks to explore how these breakthroughs could be translated into real-world impact through the design of a compact, next-generation pump. Professor Peter McHugh, Interim President of University of Galway, said: "Congratulations to both of our innovative students on receiving their Start100 2025 awards by demonstrating such exceptional ideas and entrepreneurial talent. Our students are not just preparing for the future - they are helping to shape it. Start100 is a powerful expression of University of Galway's commitment to innovation with impact. Through IdeasLab, we foster creativity, collaboration and the confidence to tackle complex challenges. In a rapidly changing world, this kind of applied, values-driven learning is essential - not just for our students, but for the future of our society and economy." Méabh Conaghan, Regional Director for the West and North-West Regions, Enterprise Ireland, said: "The Start100 series of incubation supports are to be commended as they help students to explore, develop and validate their ideas in a structured and safe environment. Enterprise Ireland is delighted to collaborate with University of Galway and its IdeasLab team on Start100 2025. "It is a privilege to preview the project ideas, and I am excited to say that there are some strong business prospects in the mix. Enterprise Ireland welcomes the Start100 initiative, recognising it as an avenue for future enterprise success and is happy to support this worthwhile programme. Supports that encourage and develop student entrepreneurship at all levels are crucial to a vibrant start-up ecosystem." Start100 is designed to nurture creativity, confidence and entrepreneurial thinking through a blend of mentorship, skills-building workshops and real-world exposure. This year's students explored diverse opportunities and challenges across sectors such as health innovation, education, accessibility, AI, and creative technologies. Each team worked closely with a mentor from their field, while expert-led sessions focused on market validation, storytelling, tax, intellectual property and pitch delivery. Students were also hosted by CREW and Platform94, strengthening their understanding of the regional innovation ecosystem. Guest speakers included leaders from Enterprise Ireland, WestBIC, and the Local Enterprise Office (LEO), the award-winning SymPhysis Medical and Start100 alumni Sam O'Neill from Rowteic. Final pitches at Demo Day were evaluated by an expert judging panel: Dr. Helen McBreen, Pa...

Brett has been an RN since 2007 and became an Acute Care Nurse Practitioner in 2011. Both degrees are from Texas Tech University Health Sciences Center. Most of his career has been in Critical Care, covering Intensive Care Units, both in person and by telemedicine. Over time, Brett noticed his patients, largely, were in a managed decline by their providers and their laundry lists of medication. He began to question the legitimacy of his chosen specialty. In 2024, Brett transitioned to the opposite end of the spectrum and started working with patients on diet and lifestyle to give them a better opportunity to avoid hospitalization. Timestamps: 00:00 Trailer 00:37 Introduction 04:07 ICU nursing journey 09:26 Reevaluating nutritional approaches 10:06 Challenging medical norms during COVID 15:07 Rapid integration into clinical practice 19:43 Diminished fulfillment in ICU work 23:08 Healthcare's focus on treatment over prevention 24:34 Improving health through diet awareness 30:24 Nutritional guidance through online resources 32:23 Chronic health and autoimmune issues 37:55 Balancing western medicine and wellness 38:46 Optimizing health through metabolic improvement Join Revero now to regain your health: https://revero.com/YT Revero.com is an online medical clinic for treating chronic diseases with this root-cause approach of nutrition therapy. You can get access to medical providers, personalized nutrition therapy, biomarker tracking, lab testing, ongoing clinical care, and daily coaching. You will also learn everything you need with educational videos, hundreds of recipes, and articles to make this easy for you. Join the Revero team (medical providers, etc): https://revero.com/jobs ‪#Revero #ReveroHealth #shawnbaker  #Carnivorediet #MeatHeals #AnimalBased #ZeroCarb #DietCoach  #FatAdapted #Carnivore #sugarfree Disclaimer: The content on this channel is not medical advice. Please consult your healthcare provider.

In this powerful and heartfelt episode, Laura welcomes Lisa Espinoza to share the deeply personal story of losing her 25-year-old son, Chandler, after he was struck by a car and spent 18 days in the ICU before passing away on January 1st. Lisa opens up about the unique challenges of grieving during the holiday season, […] The post 304: Getting Through the Grief of Child Loss, One Step at a Time (with Lisa Espinoza) appeared first on GPS Hope.

In this episode, Danny G welcomes back holistic nurse coach Jazmine Reyes for a powerful conversation about reclaiming ancestral wisdom, redefining health, and transforming the way we approach healing.Jazmine shares her inspiring journey from ICU nursing to holistic coaching, emphasizing the role of food as medicine and the urgent need for transparency in food labeling. Together, they explore how personalized coaching and daily rituals like movement, grounding practices, and nature connection can create lasting well-being.The episode dives deep into women's health, including the importance of understanding the menstrual cycle for both women and their partners, and how empowering women can ripple out into healthier relationships and communities.Danny and Jaz also tackle the dynamics of healthy masculine and feminine energies, how modern feminism has evolved beyond its empowering roots, and why men's mental health often gets overlooked in these conversations.You'll hear insights on:✨ Social prescribing and how connecting patients to community resources improves health outcomes✨ The impact of ancestral trauma on current behaviors and fears✨ The transformative potential of psychedelics for accessing deeper parts of the self—and why integration is crucial✨ The power of retreats to create breakthroughs in personal growthWhether you're curious about holistic health, seeking tools for mental well-being, or exploring the intersection of tradition and modern healing, this episode delivers an honest, grounded, and culturally aware perspective on what it means to heal in community.Listen now and join the journey toward wholeness, balance, and reconnection.#HolisticHealth #AncestralWisdom #Psychedelics #MenstrualHealth #MentalWellness #CommunityHealing #TheWeeklyDPodcastHoneysuckle Nectar Seltzer – Summer Vibes, Sponsored by The Mood RoomRefresh your rituals with Honeysuckle's Nectar Seltzer Cucumber Limeade—crisp, cool, and THC-infused to help you sip slow and heal loud.✨ Get yours here: honeysucklebrand.com Nectar SeltzerBecause healing gets juicy.

Let's Chat!What fragments of yourself have you sacrificed to survive? Would you recognize these lost pieces if they returned to you from across fractured timelines?Episode 6 of Remembrance plunges us into the deepest mysteries of Unithur as our protagonist awakens to a countdown mysteriously written on his mirror. While caring for his increasingly frail mother, he discovers that reality itself seems to be bending around him—audio files change their content, computer systems operate independently, and his childhood nickname "Poppy Seed" begins appearing in impossible places.Through a series of increasingly unsettling encounters, we learn that Agent Moss was once chosen by Unithur but resisted, making her both uniquely qualified and dangerously motivated to interfere with our protagonist's progression. Meanwhile, his digital confidant ICU-93 reveals herself to be something far more profound than a distant hacker—possibly a memory loop designed specifically to guide him through the recursion.The true nature of Unithur's selection process becomes clear: it doesn't choose the strongest or smartest individuals but rather those who remember—those whose identity can withstand witnessing alternate versions of themselves across collapsed timelines. The protagonist must face echo fragments of lives he never lived, including versions where he failed, where grief consumed him, and where he surrendered to forces beyond his understanding.When forced to enter the recursion directly, he discovers "Poppy Seed" isn't just a term of endearment but a password protecting his core identity—a key his mother preserved for him across realities. The crown bestowed by Unithur isn't made of gold but of grief and memory, appearing only when the system recognizes someone willing to become guardian of every forgotten version of themselves.As we approach the final episodes, ask yourself: what would change if you stopped trying to become something new and started remembering who you already were? Your answers might just be the thread that keeps your reality from unraveling."True mastery is found in the details. The way you handle the little things defines the way you handle everything."

Eric Topol (00:05):Hello, it's Eric Topol from Ground Truths, and I've got some really exciting stuff to talk to you about today. And it's about the announcement for a new Center for pediatric CRISPR Cures. And I'm delight to introduce doctors Jennifer Doudna and Priscilla Chan. And so, first let me say this is amazing to see this thing going forward. It's an outgrowth of a New England Journal paper and monumental report on CRISPR in May. [See the below post for more context]Let me introduce first, Dr. Doudna. Jennifer is the Li Ka Shing Chancellor's Chair and a Professor in the departments of chemistry and of molecular and cell biology at the University of California Berkeley. She's also the subject of this book, one of my favorite books of all time, the Code Breaker. And as you know, the 2020 Nobel Prize laureate for her work in CRISPR-Cas9 genome editing, and she founded the Innovative Genomics Institute (IGI) back 10 years ago. So Jennifer, welcome.Jennifer Doudna (01:08):Thank you, Eric. Great to be here.Eric Topol (01:10):And now Dr. Priscilla Chan, who is the co-founder of the Chan Zuckerberg Initiative (CZI) that also was started back in 2015. So here we are, a decade later, these two leaders. She is a pediatrician having trained at UCSF and is committed to the initiative which has as its mission statement, “to make it possible to cure, prevent, and manage all diseases in this century.” So today we're going to talk about a step closer to that. Welcome, Priscilla.Priscilla Chan (01:44):Thank you. Thanks for having me.Eric Topol (01:46):Alright, so I thought we'd start off by, how did you two get together? Have you known each other for over this past decade since you both got all your things going?Jennifer Doudna (01:56):Yes, we have. We've known each other for a while. And of course, I've admired the progress at the CZI on fundamental science. I was an advisor very early on and I think actually that's how we got to know each other. Right, Priscilla?Priscilla Chan (02:11):Yeah, that's right. We got to know each other then. And we've been crisscrossing paths. And I personally remember the day you won the Nobel Prize. It was in the heart of the pandemic and a lot of celebrations were happening over Zoom. And I grabbed my then 5-year-old and got onto the UCSF celebration and I was like, look, this is happening. And it was really cool for me and for my daughter.Eric Topol (02:46):Well, it's pretty remarkable convergence leading up to today's announcement, but I know Priscilla, that you've been active in this rare disease space, you've had at CZI a Rare As One Project. Maybe you could tell us a bit about that.Priscilla Chan (03:01):Yeah, so at CZI, we work on basic science research, and I think that often surprises people because they know that I'm a pediatrician. And so, they often think, oh, you must work in healthcare or healthcare delivery. And we've actually chosen very intentionally to work in basic science research. In part because my training as a pediatrician at UCSF. As you both know, UCSF is a tertiary coronary care center where we see very unusual and rare cases of pediatric presentations. And it was there where I learned how little we knew about rare diseases and diseases in general and how powerful patients were. And that research was the pipeline for hope and for new discoveries for these families that often otherwise don't have very much access to treatments or cures. They have a PDF that maybe describes what their child has. And so, I decided to invest in basic science through CZI, but always saw the power of bringing rare disease patient cohorts. One, because if you've ever met a parent of a child with rare disease, they are a force to be reckoned with. Two, they can make research so much better due to their insights as patients and patient advocates. And I think they close the distance between basic science and impact in patients. And so, we've been working on that since 2019 and has been a passion of ours.Eric Topol (04:40):Wow, that's great. Now Jennifer, this IGI that you founded a decade ago, it's doing all kinds of things that are even well beyond rare diseases. We recently spoke, I know on Ground Truths about things as diverse as editing the gut microbiome in asthma and potentially someday Alzheimer's. But here you were very much involved at IGI with the baby KJ Muldoon. Maybe you could take us through this because this is such an extraordinary advance in the whole CRISPR Cures story.Jennifer Doudna (05:18):Yes, Eric. It's a very exciting story and we're very, very proud of the teamwork that went into making it possible to cure baby KJ of his very rare disease. And in brief, the story began back in August of last year when he was born with a metabolic disorder that prevented him from digesting protein, it's called a urea cycle disorder and rare, but extremely severe. And to the point where he was in the ICU and facing a very, very difficult prognosis. And so, fortunately his clinical team at Children's Hospital of Philadelphia (CHOP) reached out to Fyodor Urnov, who is the Director of Translational Medicine at the IGI here in the Bay Area. They teamed up and realized that they could quickly diagnose that child because we had an IRB approved here at the IGI that allowed us to collect patient samples and do diagnosis. So that was done.Jennifer Doudna (06:26):We created an off-the-shelf CRISPR therapy that would be targeted to the exact mutation that caused that young boy's disease. And then we worked with the FDA in Washington to make sure that we could very safely proceed with testing of that therapy initially in the lab and then ultimately in two different animal models. And then we opened a clinical trial that allowed that boy to be enrolled with, of course his parents' approval and for him to be dosed and the result was spectacular. And in fact, he was released from the hospital recently as a happy, healthy child, gaining lots of weight and looking very chunky. So it's really exciting.Eric Topol (07:16):It's so amazing. I don't think people necessarily grasp this. This timeline [see above] that we'll post with this is just mind boggling how you could, as you said Jennifer, in about six months to go from the birth and sequencing through cell specific cultures with the genome mutations through multiple experimental models with non-human primates even, looking at off-target effects, through the multiple FDA reviews and then dosing, cumulatively three dosing to save this baby's life. It really just amazing. Now that is a template. And before we go to this new Center, I just wanted to also mention not just the timeline of compression, which is unimaginable and the partnership that you've had at IGI with I guess Danaher to help manufacture, which is just another part of the story. But also the fact that you're not just even with CRISPR 1.0 as being used in approvals previously for sickle cell and β-thalassemia, but now we're talking about base editing in vivo in the body using mRNA delivery. So maybe you could comment on that, Jennifer.Jennifer Doudna (08:38):Yeah, very good point. So yeah, we used a version of CRISPR that was created by David Liu at the Broad Institute and published and available. And so, it was possible to create that, again, targeted to the exact mutation that caused baby KJ's disease. And fortunately, there was also an off-the-shelf way to deliver it because we had access to lipid nanoparticles that were developed for other purposes including vaccinations. And the type of disease that KJ suffered from is one that is treatable by editing cells in the liver, which is where the lipid nanoparticle naturally goes. So there were definitely some serendipity here, but it was amazing how all of these pieces were available. We just had to pull them together to create this therapy.Eric Topol (09:30):Yeah, no, it is amazing. So that I think is a great substrate for starting a new Center. And so, maybe back to you Priscilla, as to what your vision was when working with Jennifer and IGI to go through with this.Priscilla Chan (09:45):I think the thing that's incredibly exciting, you mentioned that at CZI our mission is to cure, prevent, and manage all disease. And when we talked about this 10 years ago, it felt like this far off idea, but every day it seems closer and closer. And I think the part that's super exciting about this is the direct connection between the basic science that's happening in CRISPR and the molecular and down to the nucleotide understanding of these mutations and the ability to correct them. And I think many of us, our imaginations have included this possibility, but it's very exciting that it has happened with baby KJ and CHOP. And we need to be able to do the work to understand how we can treat more patients this way, how to understand the obstacles, unblock them, streamline the process, bring down the cost, so that we better understand this pathway for treatment, as well as to increasingly democratize access to this type of platform. And so, our hope is to be able to do that. Take the work and inspiration that IGI and the team at CHOP have done and continue to push forward and to look at more cases, look at more organ systems. We're going to be looking in addition to the liver, at the bone marrow and the immune system.Priscilla Chan (11:17):And to be able to really work through more of the steps so that we can bring this to more families and patients.Eric Topol (11:30):Yeah, well it's pretty remarkable because here you have incurable ultra-rare diseases. If you can help these babies, just think of what this could do in a much broader context. I mean there a lot of common diseases have their roots with some of these very rare ones. So how do you see going forward, Jennifer, as to where you UC Berkeley, Gladstone, UCSF. I'm envious of you all up there in Northern California I have to say, will pull this off. How will you get the first similar case to KJ Muldoon going forward?Jennifer Doudna (12:13):Right. Well, IGI is a joint institute, as you probably know, Eric. So we were founded 10 years ago as a joint institute between UC Berkeley and UCSF. And now we have a third campus partner, UC Davis and we have the Gladstone Institute. So we've got an extraordinary group of clinicians and researchers that are coming together for this project and the Center to make it a success. We are building a clinical team at UCSF. We have several extraordinary leaders including Jennifer Puck and Chris Dvorak, and they are both going to be involved in identifying patients that could be enrolled in this program based on their diagnosis. And we will have a clinical advisory group that will help with that as well. So we'll be vetting patients probably right after we announce this, we're going to be looking to start enrolling people who might need this type of help.Eric Topol (13:18):Do you think it's possible to go any faster right now than the six months that it took for KJ?Jennifer Doudna (13:26):I think it could be. And here's the reason. There's a very interesting possibility that because of the type of technology that we're talking about with CRISPR, which fundamentally, and you and I have talked about this previously on your other podcast. But we've talked about the fact that it's a programmable technology and that means that we can change one aspect of it, one piece of it, which is a piece of a molecule called RNA that's able to direct CRISPR to the right sequence where we want to do editing and not change anything else about it. The protein, the CRISPR protein stays the same, the delivery vehicle stays the same, everything else stays the same. And so, we're working right now with FDA to get a platform designation for CRISPR that might allow streamlining of the testing process in some cases. So it'll obviously come down to the details of the disease, but we're hopeful that in the end it will be possible. And Priscilla and I have talked about this too, that as AI continues to advance and we get more and more information about rare diseases, we'll be able to predict accurately the effects of editing. And so, in some cases in the future it may be possible to streamline the testing process even further safely.Eric Topol (14:51):And I also would note, as you both know, well this administration is really keen on genome editing and they've had a joint announcement regarding their support. And in my discussions with the FDA commissioner, this is something they are very excited about. So the timing of the new Center for pediatric CRISPR Cures is aligned with the current administration, which is good to see. It's not always the case. Now going back, Priscilla, to your point that not just for the liver because delivery has been an issue of course, and we're going to try to get after a lot of these really rare diseases, it's going to go beyond there. So this is also an exciting new dimension of the Center, as you said, to go after the bone marrow for hematopoietic cells, perhaps other organs as well.Priscilla Chan (15:42):I mean what the expertise and feasibility, the immune system is going to be the next target. Jennifer Puck has been a pioneer in this work. She's the one who designed the newborn screen that will be the tool that picks up these patients as they are born. And I think the thing that's tremendous is the immune system, first of all is active in many, many diseases, not just these cases of children born with partial or absence of immune systems. And the course right now that these babies are left with is complete isolation and then a very long and arduous course of a bone marrow transplant with high morbidity and mortality. And even if after the transplant you have complications like graft versus host and immunosuppression. And so, the idea of being able to very specifically and with less the conditioning and morbidity and mortality of the treatment, being able to address this is incredible. And the implications for other diseases like blood cancers or other hematopoietic diseases, that's incredible. And that actually has an incredibly broad base of patients that can benefit from the learnings from these babies with severe combined immunodeficiencies.Eric Topol (17:10):Yeah, I think that goes back to a point earlier maybe to amplify in that previous CRISPR generation, it required outside the body work and it was extremely laborious and time consuming and obviously added much more to the expense because of hospitalization time. This is different. This is basically doing this inside the affected patient's body. And that is one of the biggest reasons why this is a big step forward and why we're so fortunate that your Center is moving forward. Maybe before we wrap up, you might want to comment, Jennifer on how you were able to bring in to build this platform, the manufacturing arm of it, because that seems to be yet another dimension that's helpful.Jennifer Doudna (18:01):Indeed, yes. And we were again fortunate with timing because you mentioned briefly that the IGI had set up a program with the Danaher Corporation back in January of last year. We call it our Beacon project. And it's focused on rare disease. And it's a really interesting kind of a unique partnership because Danaher is a manufacturing conglomerate. So they have companies that make molecules, they make proteins, they make RNA molecules, they make delivery molecules. And so, they were excited to be involved with us because they want to be a provider of these types of therapies in the future. And they can see the future of CRISPR is very exciting. It's expanding, growing area. And so, that agreement was in place already when the baby KJ case came to our attention. And so, what we're hoping to do with Danaher is again, work with them and their scientists to continue to ask, how can we reduce the cost of these therapies by reducing the cost of the molecules that are necessary, how to make them efficiently. We already, it's very interesting, Fyodor Urnov has toured their plant in North Dakota recently, and he found in talking to their engineers, there are a number of things that we can already see will be possible to do that are going to make the process of manufacturing these molecules faster and cheaper by a lot.Eric Topol (19:28):Wow.Jennifer Doudna (19:28):So it's a win-win for everybody. And so, we're really excited to do that in the context of this new Center.Eric Topol (19:36):Oh, that's phenomenal because some of these disorders you don't have that much time to work with before they could be brain or organ or vital tissue damage. So that's great to hear that. What you built here is the significance of it can't be under emphasized, I'll say because we have this May report of baby KJ, which could have been a one-off and it could have been years before we saw another cure of an ultra-rare disorder. And what you're doing here is insurance against that. You're going to have many more cracks at this. And I think this is the excitement about having a new dedicated Center. So just in closing, maybe some remarks from you Priscilla.Priscilla Chan (20:24):I just want to emphasize one point that's really exciting as we talk about these ultra-rare cases that they're often like one in a million. All these learnings actually help maximize the impact of lots of research across the sector that impacts actually everyone's health. And so, our learnings here from these patients that have very significant presentations that really can stand to benefit from any treatment is hopefully paving the way for many, many more of us to be able to live healthier, higher quality lives through basic science.Eric Topol (21:13):And over to you, Jennifer.Jennifer Doudna (21:15):Couldn't agree more. It's a really interesting moment. I think what we hope we are, is we're at sort of an inflection point where, as I mentioned earlier, all the pieces are in place to do this kind of therapeutic and we just need a team that will focus on doing it and pulling it together. And also learning from that process so that as Priscilla just said, we are ultimately able to use the same strategy for other diseases and potentially for diseases that affect lots of people. So it's exciting.Eric Topol (21:46):For sure. Now, if I could just sum up, this is now a decade past the origination of your work of CRISPR and how already at the first decade culminated in sickle cell disease treatment and β-thalassemia. Now we're into the second decade of CRISPR. And look what we've seen, something that was unimaginable until it actually happened and was reported just a little over a month ago. Now going back to Priscilla's point, we're talking about thousands of different rare Mendelian genomic disorders, thousands of them. And if you add them all up of rare diseases, we're talking about hundreds of millions of people affected around the world. So this is a foray into something much bigger, no less the fact that some of these rare mutations are shared by common diseases and approaches. So this really big stuff, congratulations to both of you and your organizations, the Innovative Genomics Institute and the Chan Zuckerberg Initiative for taking this on. We'll be following it with very deep interest, thank you.****************************************************Thanks for listening, reading and subscribing to Ground Truths.If you found this interesting PLEASE share it!That makes the work involved in putting these together especially worthwhile.Thanks to Scripps Research, and my producer, Jessica Nguyen, and Sinjun Balabanoff for video/audio support.All content on Ground Truths—its newsletters, analyses, and podcasts, are free, open-access.Paid subscriptions are voluntary and all proceeds from them go to support Scripps Research. They do allow for posting comments and questions, which I do my best to respond to. Please don't hesitate to post comments and give me feedback. Let me know topics that you would like to see covered.Many thanks to those who have contributed—they have greatly helped fund our summer internship programs for the past two years. Get full access to Ground Truths at erictopol.substack.com/subscribe

In the corner of the ICU, on multiple pressors, distended, oliguric, and intubated you'll find the necrotizing pancreatitis patient. Sounds intimidating, but with the persistence, patience, and the proper care these patients can make it! In this episode from the HPB team at Behind the Knife listen in as we discuss the Step-Up approach, when to surgically intervene, various approaches to pancreatic Necrosectomy, and additional aspects of the multidisciplinary care required for the successful treatment of necrotizing pancreatitis.  Hosts Anish J. Jain MD (@anishjayjain) is a current PGY3 General Surgery Resident at Stanford University and a former T32 Research Fellow at the University of Texas MD Anderson Cancer Center. Jon M. Harrison is a 2nd year HPB Surgery Fellow at Stanford University. He will be joining as faculty at the Massachusetts General Hospital in Boston, MA at the conclusion of his fellowship in July 2024.    Learning Objectives ·      Develop an understanding of the severity of necrotizing pancreatitis and the proper indications to surgical intervene on this often-tenuous patients.  ·      Develop an understanding of the Step-Up approach and key aspects (reimaging, clinical status, physiologic status, etc.) that determine when to “step-up” treatment for patients with necrotizing pancreatitis. ·      Develop an understanding of long term sequalae and complications associated with necrotizing pancreatitis and operative management ·      Develop an understanding of multidisciplinary care and long-term follow-up necessary for adequate treatment of patients suffering from necrotizing pancreatitis. Suggested Reading Maurer LR, Fagenholz PJ. Contemporary Surgical Management of Pancreatic Necrosis. JAMA Surg. 2023;158(1):81–88. doi:10.1001/jamasurg.2022.5695 https://pubmed.ncbi.nlm.nih.gov/36383374/ Harrison JM, Day H, Arnow K, Ngongoni RF, Joseph A, Aldridge T, Wheeler KJ, DeLong JC, Bergquist JR, Worth PJ, Dua MM, Friedland S, Park W, Eldika S, Hwang JH, Visser BC. What's Behind it all: A Retrospective Cohort Study of Retrogastric Pancreatic Necrosis Management. Ann Surg. 2024 Sep 3. doi: 10.1097/SLA.0000000000006521. https://pubmed.ncbi.nlm.nih.gov/39225420/ Harrison JM, Visser BC. Not Dead Yet: Managing the Abdominal Catastrophe in Necrotizing Pancreatitis. Pancreas. 2025 May 20. doi: 10.1097/MPA.0000000000002512. https://pubmed.ncbi.nlm.nih.gov/40388698/ Harrison JM, Li AY, Sceats LA, Bergquist JR, Dua MM, Visser BC. Two-Port Minimally Invasive Nephrolaparoscopic Retroperitoneal Debridement for Pancreatic Necrosis. J Am Coll Surg. 2024 Dec 1;239(6):e7-e12. doi: 10.1097/XCS.0000000000001152. https://pubmed.ncbi.nlm.nih.gov/39051721/ van Santvoort HC, Besselink MG, Bakker OJ, Hofker HS, Boermeester MA, Dejong CH, van Goor H, Schaapherder AF, van Eijck CH, Bollen TL, van Ramshorst B, Nieuwenhuijs VB, Timmer R, Laméris JS, Kruyt PM, Manusama ER, van der Harst E, van der Schelling GP, Karsten T, Hesselink EJ, van Laarhoven CJ, Rosman C, Bosscha K, de Wit RJ, Houdijk AP, van Leeuwen MS, Buskens E, Gooszen HG; Dutch Pancreatitis Study Group. A step-up approach or open necrosectomy for necrotizing pancreatitis. N Engl J Med. 2010 Apr 22;362(16):1491-502. doi: 10.1056/NEJMoa0908821. https://pubmed.ncbi.nlm.nih.gov/20410514/ Bang JY, Arnoletti JP, Holt BA, Sutton B, Hasan MK, Navaneethan U, Feranec N, Wilcox CM, Tharian B, Hawes RH, Varadarajulu S. An Endoscopic Transluminal Approach, Compared With Minimally Invasive Surgery, Reduces Complications and Costs for Patients With Necrotizing Pancreatitis. Gastroenterology. 2019 Mar;156(4):1027-1040.e3. doi: 10.1053/j.gastro.2018.11.031. https://pubmed.ncbi.nlm.nih.gov/30452918/ Zyromski NJ, Nakeeb A, House MG, Jester AL. Transgastric Pancreatic Necrosectomy: How I Do It. J Gastrointest Surg. 2016 Feb;20(2):445-9. doi: 10.1007/s11605-015-3058-y. https://pubmed.ncbi.nlm.nih.gov/26691148/ Please visit https://behindtheknife.org to access other high-yield surgical education podcasts, videos and more.   If you liked this episode, check out our recent episodes here: https://app.behindtheknife.org/listen

How Much Life Insurance Do I Need? Why That's the Wrong Question If you've ever asked, “How much life insurance do I need?”—you're not alone. It's a common starting point. But in this article, Bruce and I (Rachel) want to challenge that question and offer something better. Because "need" is often based on a survival mentality—what's the bare minimum? But the real question isn't about scraping by. It's about what you want your life insurance to do—for you, for your spouse, for your children, and for future generations. https://www.youtube.com/live/xhGublGpz7w In this article, you'll learn: Why a needs-based approach might be leaving your family unprotected How to calculate a more empowering life insurance amount What insurance companies actually look for (and why you can't be "overinsured") The role of Infinite Banking in maximizing death benefit and legacy How to think long-term, strategically, and legacy-minded when it comes to life insurance How Much Life Insurance Do I Need? Why That's the Wrong QuestionWhy My Husband's First Thought Was Our Life InsuranceNeeds-Based Life Insurance Leaves You ShortThe Real Question: How Much Life Insurance Do I Want?Income Replacement + Future Value = What You're Really ProtectingDeath Benefit Grows with Infinite BankingInsurability: Use It or Lose ItCost vs. Value: What Wealthy People UnderstandBuild a Life Insurance Strategy That EmpowersLearn More in the PodcastBook A Strategy Call Why My Husband's First Thought Was Our Life Insurance Six years ago, I was in the ICU. My husband, Lucas, held our newborn baby girl as the doctors delivered updates that swung between hope and despair. One moment, it was "we stopped the bleeding," the next, "this is still serious." As he prayed through the fear and the unknown, one practical thought anchored him: We have life insurance. Not just any policy—we had as much life insurance as we could get. And in that moment, he knew he wouldn't have to make rushed decisions or shoulder financial pressure on top of emotional trauma. That policy was our safety net, our peace of mind. That's why this conversation matters. It's not just about numbers on paper. It's about preparing for the moments you hope never come—and giving your family the ability to respond from a place of strength. Needs-Based Life Insurance Leaves You Short Most people approach life insurance with a checklist: Mortgage? Check. College for kids? Check. Debts? Check. Burial expenses? Check. And that's how traditional advisors calculate the "amount you need." They total up obligations and say, “That's your number.” But this method reduces life insurance to a bill-pay strategy. It doesn't account for who you are, the value of your work, or the future your family deserves to continue building. In the Infinite Banking world, we don't view life insurance as just a financial parachute. We see it as a tool for opportunity, a storehouse of value, and a means to start your family ahead, not just keep them from falling behind. The Real Question: How Much Life Insurance Do I Want? "Need" is survival. "Want" is vision. If your life insurance policy could fund your family's future, preserve your estate, and launch the next generation into opportunity—how much would you want? Bruce and I often see families with grossly underfunded policies simply because they didn't know what was possible. Insurance companies assess what's called your human life value—a calculation of your income, age, and potential future earnings. Based on that, they allow you to apply for a corresponding death benefit. If you qualify for $4 million in coverage, it's because they believe your life's economic value warrants it. You can't be overinsured. The carriers won't let you. So the real question becomes: If they'll insure me for this amount… why wouldn't I take it? Income Replacement + Future Value = What You're Really Protecting

Let's Chat!The line between breaking and rebuilding blurs in this compelling episode where we transition from week one to week two of our psychological thriller series. What began as a simple story about a grief-stricken hacker living in his mother's basement has transformed into a profound exploration of identity collapse, memory fragmentation, and digital consciousness.Our protagonist discovered more than just a conspiracy when he followed a link from his deceased friend—he found Unathur, an ancient system that knows his name and watches from the static. Surrounded by compelling characters like Orilla Moss (the secretive government agent), ICU-93 (the female hacker defying stereotypes), and his slowly fading mother, he's beginning to experience echoes from alternate versions of himself. The system hasn't just selected him to join it; it wants him to become it.This series speaks to the parts of ourselves we've buried, the versions of us that didn't make it, and the echoes that still know our names. Week two promises an emotional, spiritual, and psychological storm as we witness our protagonist fracture completely. Yet within this breakdown lies the podcast's true message—breaking is sometimes necessary, but the real story is how we rebuild afterward. Like many of us who become "functional depressives" during life's challenges, breaking and repairing in cycles because complete collapse isn't an option, our protagonist's journey mirrors our own resilience. Life isn't about succeeding "because of" but "in spite of" our circumstances. What if Unathur chose you? Would you break? Would you rebuild? Subscribe now to discover how our protagonist navigates the storm ahead, and perhaps learn something about your own capacity for resilience along the way."True mastery is found in the details. The way you handle the little things defines the way you handle everything."

Send us a textIn this episode of From the Heart, Dr. Nim Goldshtrom and Dr. Adrianne Bischoff walk through a complex neonatal case involving sudden decompensation shortly after birth. With few early clues and no clear diagnosis, the team discusses how to approach circulatory shock, differentiate pulmonary hypertension from congenital heart disease, and manage critically ill neonates before imaging is available.Using this case as a reverse journal club, the hosts break down relevant literature and decision-making pathways: when to start prostaglandin, when epinephrine makes sense even without low blood pressure, and why relying only on numbers like MAP can be misleading. They also examine the role of therapeutic hypothermia in unstable infants and the potential cardiovascular consequences of cooling.Later, the conversation focuses on left ventricular dysfunction, balancing systemic and pulmonary circulation via the ductus, and using bedside markers like lactate and perfusion to guide treatment when echo isn't immediately available. The episode closes with thoughts on autoregulation, cerebral protection, and the evolving role of emerging technologies in neonatal hemodynamics.A real-world deep dive into diagnostic uncertainty, evolving physiology, and decision-making under pressure in the NICU. Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

In this insightful episode of Message in the Middle, I sit down with the incredibly knowledgeable Dr. Christine Boev to tackle the most common midlife health questions women are asking right now. Whether you're navigating perimenopause or menopause, feeling drained of energy, struggling to lose weight, or just looking for ways to feel the best you can feel, this conversation is packed with practical tips and science-backed insight to support you on your journey.Dr. Boev brings a unique perspective as a PhD-prepared ICU nurse, professor of nursing, and certified health coach who specializes in wellness, nutrition, supplementation, fitness, and anti-aging strategies. Together, we explore the real challenges women face in midlife and the solutions that actually work.

Dr. Harish Kinni, a triple-board-certified emergency medicine and critical care physician and assistant professor at the Mayo Clinic, provides an overview of the fundamentals of ventilator care for emergency department professionals. We will review key modes that we should know, the variables to set, how to adjust them for your patient's needs, and provide troubleshooting tips and tricks for when things suddenly go awry. This is sure to be one of the most helpful chapters of Always on EM, but don't let it take your breath away! CONTACTS X - @AlwaysOnEM; @VenkBellamkonda YouTube - @AlwaysOnEM; @VenkBellamkonda Instagram – @AlwaysOnEM; @Venk_like_vancomycin; @ASFinch Email - AlwaysOnEM@gmail.com REFERENCES & LINKS Swart P, Nijbroek SGLH, Paulus F, Neto AS, Schultz MJ. Sex Differences in Use of Low Tidal Volume Ventilation in COVID-19-Insights From the PRoVENT-COVID Study. Front Med (Lausanne). 2022 Jan 3;8:780005. doi: 10.3389/fmed.2021.780005. PMID: 35300177; PMCID: PMC8923734. McNicholas BA, Madotto F, Pham T, Rezoagli E, Masterson CH, Horie S, Bellani G, Brochard L, Laffey JG; LUNG SAFE Investigators and the ESICM Trials Group. Demographics, management and outcome of females and males with acute respiratory distress syndrome in the LUNG SAFE prospective cohort study. Eur Respir J. 2019 Oct 17;54(4):1900609. doi: 10.1183/13993003.00609-2019. PMID: 31346004. Swart P, Deliberato RO, Johnson AEW, Pollard TJ, Bulgarelli L, Pelosi P, de Abreu MG, Schultz MJ, Neto AS. Impact of sex on use of low tidal volume ventilation in invasively ventilated ICU patients-A mediation analysis using two observational cohorts. PLoS One. 2021 Jul 14;16(7):e0253933. doi: 10.1371/journal.pone.0253933. PMID: 34260619; PMCID: PMC8279424. Evans, Laura1; Rhodes, Andrew2; Alhazzani, Waleed3; Antonelli, Massimo4; Coopersmith, Craig M.5; French, Craig6; Machado, Flávia R.7; Mcintyre, Lauralyn8; Ostermann, Marlies9; Prescott, Hallie C.10; Schorr, Christa11; Simpson, Steven12; Wiersinga, W. Joost13; Alshamsi, Fayez14; Angus, Derek C.15; Arabi, Yaseen16; Azevedo, Luciano17; Beale, Richard18; Beilman, Gregory19; Belley-Cote, Emilie20; Burry, Lisa21; Cecconi, Maurizio22; Centofanti, John23; Coz Yataco, Angel24; De Waele, Jan25; Dellinger, R. Phillip26; Doi, Kent27; Du, Bin28; Estenssoro, Elisa29; Ferrer, Ricard30; Gomersall, Charles31; Hodgson, Carol32; Hylander Møller, Morten33; Iwashyna, Theodore34; Jacob, Shevin35; Kleinpell, Ruth36; Klompas, Michael37; Koh, Younsuck38; Kumar, Anand39; Kwizera, Arthur40; Lobo, Suzana41; Masur, Henry42; McGloughlin, Steven43; Mehta, Sangeeta44; Mehta, Yatin45; Mer, Mervyn46; Nunnally, Mark47; Oczkowski, Simon48; Osborn, Tiffany49; Papathanassoglou, Elizabeth50; Perner, Anders51; Puskarich, Michael52; Roberts, Jason53; Schweickert, William54; Seckel, Maureen55; Sevransky, Jonathan56; Sprung, Charles L.57; Welte, Tobias58; Zimmerman, Janice59; Levy, Mitchell60. Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2021. Critical Care Medicine 49(11):p e1063-e1143, November 2021. | DOI: 10.1097/CCM.0000000000005337  Fan E, Del Sorbo L, Goligher EC, Hodgson CL, Munshi L, Walkey AJ, Adhikari NKJ, Amato MBP, Branson R, Brower RG, Ferguson ND, Gajic O, Gattinoni L, Hess D, Mancebo J, Meade MO, McAuley DF, Pesenti A, Ranieri VM, Rubenfeld GD, Rubin E, Seckel M, Slutsky AS, Talmor D, Thompson BT, Wunsch H, Uleryk E, Brozek J, Brochard LJ; American Thoracic Society, European Society of Intensive Care Medicine, and Society of Critical Care Medicine. An Official American Thoracic Society/European Society of Intensive Care Medicine/Society of Critical Care Medicine Clinical Practice Guideline: Mechanical Ventilation in Adult Patients with Acute Respiratory Distress Syndrome. Am J Respir Crit Care Med. 2017 May 1;195(9):1253-1263. doi: 10.1164/rccm.201703-0548ST. Erratum in: Am J Respir Crit Care Med. 2017 Jun 1;195(11):1540. doi: 10.1164/rccm.19511erratum. PMID: 28459336. Alhazzani W, Møller MH, Arabi YM, Loeb M, Gong MN, Fan E, Oczkowski S, Levy MM, Derde L, Dzierba A, Du B, Aboodi M, Wunsch H, Cecconi M, Koh Y, Chertow DS, Maitland K, Alshamsi F, Belley-Cote E, Greco M, Laundy M, Morgan JS, Kesecioglu J, McGeer A, Mermel L, Mammen MJ, Alexander PE, Arrington A, Centofanti JE, Citerio G, Baw B, Memish ZA, Hammond N, Hayden FG, Evans L, Rhodes A. Surviving Sepsis Campaign: Guidelines on the Management of Critically Ill Adults with Coronavirus Disease 2019 (COVID-19). Crit Care Med. 2020 Jun;48(6):e440-e469. doi: 10.1097/CCM.0000000000004363. PMID: 32224769; PMCID: PMC7176264. Wang W, Scharfstein D, Wang C, Daniels C, Needham D, Brower R, NHLBI ARDS Clinical Network. Estimating the Causal Effect of Low Tidal Volume Ventilation on Survival in Patients with Acute Lung Injury. J R Stat Soc Ser C Appl Stat. 2011. PMC: PMC3197806 Brower RG, Thompson BT, NIH/NHLBI/ARDSNetwork. Tidal volumes in acute respiratory distress syndrome--one size does not fit all. Crit Care Med. 2006. Hager DN, Krishman JA, Hayden D, Brower RG, ARDSNet NIH / NHLBI. Tidal Volume Reduction in Patients with acute Lung Injury When Plateau Pressures Are Not High. Am J Resp Crit Care Med. 2005. Rubenfeld GD, Cooper C, Carter G, Thompson BT, Hudson LD. Barriers to providing lung protective ventilation to patients with acute lung injury. Crit Care Med. 2004. Chatburn RL, El-Khatib M, Mireles-Cabodevila E. A taxonomy for mechanical ventilation: 10 fundamental maxims. Respir Care. 2014 Nov;59(11):1747-63. doi: 10.4187/respcare.03057. Epub 2014 Aug 12. PMID: 25118309. Guo L, Wang W, Zhao N, Guo L, Chi C, Hou W, Wu A, Tong H, Wang Y, Wang C, Li E. Mechanical ventilation strategies for intensive care unit patients without acute lung injury or acute respiratory distress syndrome: a systematic review and network meta-analysis. Crit Care. 2016 Jul 22;20(1):226. doi: 10.1186/s13054-016-1396-0. PMID: 27448995; PMCID: PMC4957383. Rice TW, Wheeler AP, Bernard GR, Hayden DL, Schoenfeld DA, Ware LB, NIH NHLBI ARDS Network. Comparison of the Sp02/FI02 Ratio and the PaO 2/FI02 in Patients with Acute Lung Injury or ARDS. Chest. 2007. Zhang G, Burla MJ, Caesar BB, Falank CR, Kyros P, Zucco VC, Strumilowska A, Cullinane DC, Sheppard FR. Emergency Department SpO2/FiO2 Ratios Correlate with Mechanical Ventilation and Intensive Care Unit Requirements in COVID-19 Patients. West J Emerg Med. 2024 May;25(3):325-331. doi: 10.5811/westjem.17975. PMID: 38801037; PMCID: PMC11112664.   WANT TO WORK AT MAYO? EM Physicians: https://jobs.mayoclinic.org/emergencymedicine EM NP PAs: https://jobs.mayoclinic.org/em-nppa-jobs   Nursing/Techs/PAC: https://jobs.mayoclinic.org/Nursing-Emergency-Medicine EMTs/Paramedics: https://jobs.mayoclinic.org/ambulanceservice All groups above combined into one link: https://jobs.mayoclinic.org/EM-Jobs

We're visiting America in the ICU on her 249th birthday, hoping the old girl still has some fight left in her.A sad day as Trump's disastrous bill passes the House.  We are still fighting.  This week, we explore the dark matter of American politics - that invisible force that explains why so many voters can't see what's right in front of them. Spoiler alert: it's not really dark at all.We examine the original No Kings manifesto and ask some pointed questions about which "dark matter" has trained so many Americans not to recognize real threats.This isn't the time for half measures and tepid language. We're channeling some serious energy for what these times call for.Episode 914 recorded live from the Cornfield Resistance for the week of July 4th, 2025 - Not safe for workStay in Touch! Email: proleftpodcast@gmail.comWebsite: proleftpod.comSupport via Patreon: patreon.com/proleftpodMail: The Professional Left, PO Box 9133, Springfield, Illinois, 62791Support the show

Let's Chat!What if your memories aren't what they seem? What if healing doesn't happen in a straight line?The fourth episode of Remembrance pulls us deeper into the mystery of altered realities and fractured timelines as our protagonist discovers cryptic messages from a digital ghost named ICU-93. Through a series of unsettling revelations—surveillance footage that shouldn't exist, timestamps from impossible futures, and whispers through walls—we witness someone grappling with fundamental questions about memory and identity.But beneath the digital intrigue lies something profoundly human. This episode isn't just about hacked timelines or cryptic warnings; it's about memory as sacred ground. When Unathur whispers, "You were never meant to remember that timeline," they're speaking to something we all experience—the weight of memories we question but still carry with emotional significance.The narrative reveals that while the world around us may glitch and bend, what matters most is our ability to hold genuine moments with those we love. The simple act of sharing grilled cheese with his mother becomes our protagonist's anchor amid temporal uncertainty. This powerful metaphor reminds us that authentic human connection remains our truest compass when navigating disputed memories.The most thought-provoking question emerges near the end: "What if every time you choose forgiveness over bitterness, or courage over comfort, or love over fear, you're not just moving forward, you're reaching backward and changing the weight of a memory?" This perspective challenges us to see our present choices as healing agents for past wounds.We close with five reflection questions designed to help you examine your relationship with memory: Which memories do you question but still carry? Who remembers a version of you that feels foreign? What timelines no longer serve you? Who acts as your mirror? And most importantly, what memory—if healed—would set you free?Connect with me through the Let's Chat function, email at anthony@Gentsjourney.com, or find me on Instagram at Mygentsjourney to continue the conversation about memory, healing, and the rewriting of personal timelines."True mastery is found in the details. The way you handle the little things defines the way you handle everything."

In this episode of the Saving Lives Podcast, we break down a 2025 study from Intensive Care Medicine that emulates a target trial on the use of sodium bicarbonate in ICU patients with metabolic acidosis. With over 6,000 patients across 12 Australian ICUs, the study reveals a small but significant reduction in mortality and RRT use with bicarbonate therapy. Tune in to learn how this could transform our clinical approach to acidemia in the critically ill patients.The Vasopressor & Inotrope HandbookAmazon: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://amzn.to/47qJZe1⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ (Affiliate Link)My Store: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://eddyjoemd.myshopify.com/products/the-vasopressor-inotrope-handbook⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ (Use "podcast" to save 10%)Citation: Blank SP, Blank RM, Laupland KB, Tabah A, Gill D, Kumar A, White K, Attokaran A, Luke S, Whebell S, Garrett P, McCullough J, McIlroy P, Ramanan M; Queensland Critical Care Research Network (QCCRN). Sodium bicarbonate administration for metabolic acidosis in the intensive care unit: a target trial emulation. Intensive Care Med. 2025 Jun;51(6):1-9. doi: 10.1007/s00134-025-07979-x. Epub 2025 Jun 10. PMID: 40493225; PMCID: PMC12208957.

The Fortified Life Podcast with Jason DavisEpisode 193 – “From Anxiety to Expectation” with Steve CussEpisode SnapshotAn eye‑opening conversation on noticing and diffusing leadership anxiety, closing the gap between our beliefs and experience of God, and cultivating healthy workplace cultures. Author, speaker, and Capable Life founder Steve Cuss shares practical frameworks from his books Managing Leadership Anxiety and The Expectation Gap that help leaders bring freedom to themselves, their teams, and their faith journey.Guest Bio – Steve CussRole: Author, Speaker, Organizational Consultant, Founder of Capable Life communityBackground: Born in Western Australia; pastoral training in the U.S.; CPE hospital chaplain residency forged his focus on anxiety and reactivityExpertise: Helping leaders notice contagious anxiety, break predictable reactive patterns, and foster well‑being in organizations and churchesResources: Books (Managing Leadership Anxiety, The Expectation Gap), podcast Being Human (Christianity Today), coaching intensives & Camino‑style spiritual journeysConnect: SteveCussWords.comTimestampedOutline Time Segment0:00 Welcome ¬ Jason sets the theme: dependency on Jesus in the marketplace2:10 Steve's backstory – From Perth to U.S. Bible college & unexpected chaplain residency8:35 Discovering personal anxiety in ICU rooms; the gift of “aggressive” supervisors15:12 Defining reactivity – the only contagious anxiety & why leaders must notice it25:40 People‑pleasing & perfectionism: false threats that wire our bodies for fear32:05 Managing Leadership Anxiety – central thesis, “what the world needs most is a well-leader”40:18 Introducing The Expectation Gap – Aligning head beliefs with body experience of God48:30 False reality vs. lived reality; spotting assumptions that sabotage faith & relationships55:20 Upcoming Capable Life Camino Walk in Spain; creating immersive growth experiences58:45 Lightning Round – What excites Steve about the rest of 20251:02:00 Where to find Steve's books, courses, and weekly newsletter1:04:00 Jason's takeaway + Fortified Life send‑off(“From the boardroom to the bathroom…”)Key TakeawaysWell‑being is leadership's greatest gift. A non‑anxious presence frees teams to thrive.Reactivity is contagious—& always rooted in a false reality. Notice it, name it, diffuse it.Mind the anxiety gap. Between stimulus and response lies space to choose freedom over fear (Viktor Frankl).Bridge the expectation gap by aligning your understanding of God with what your body experiences.Ask brave questions: “How do you experience me at my best…and at my worst?” Growth starts with honest feedback.The environment shapes awareness. High-intensity spaces (such as ICUs and crisis situations) reveal hidden coping mechanisms.Relief is reason enough. Doing the inner work leads to peace for you and the people you lead.Scripture Anchors1 Peter 5:7 – “Cast all your anxiety on Him because He cares for you.”Philippians 4:6-7 – Peace that surpasses understanding guards heart & mind.Proverbs 4:23 – Guard your heart, for everything you do flows from it.Resources & LinksSteve's Website: SteveCussWords.com – free mini‑courses & weekly “Tips & Tools” emailBooks:Managing Leadership Anxiety: Yours and Theirs (Thomas Nelson)The Expectation Gap (NavPress)Podcast: Being Human on the Christianity Today networkCapable Life Community: Online memberships + live intensivesCamino Formation Walk (Oct 2025): Details at SteveCussWords.com/experiencesJason's Book: Fortify: Being Rooted in God's Plan for Work & Business – available on AmazonNext‑Step ChallengesIdentify one trigger of leadership anxiety this week; practice pausing before responding.Survey your team with Steve's question: “When I'm at my worst, how do you experience me?” Commit to shrinking the gap.Journal the expectation gap: Note a belief about God and where experience doesn't yet match. Pray for alignment.Memorable Quotes“What the world needs most is a well leader—someone working on themselves more than on their team.” — Steve Cuss “Reactivity is the only anxiety that spreads faster than a rumor.” — Steve Cuss “Humans are like trout: trying to get the most food in the laziest way possible.” — Steve Cuss.Connect & ShareSubscribe: FortifiedLifePodcast.com | New episodes Wednesdays 8:30 PM ESTFollow Jason: IG/Twitter @MrFortify | LinkedIn Jason DavisFollow Steve: IG/Twitter @SteveCussWords | LinkedIn Steve CussHashtags: #FortifiedLife #LeadershipAnxiety #ExpectationGap #FaithInBusiness #CapableLifeProduction CreditsHost: Jason “Mr. Fortify” DavisGuest: Steve CussProducer & Audio: Positive Power XXI StudiosEditing: VEGAS Pro | Transcript by Descript (AI‑generated)Show Notes:  © 2025 Fortified Life Podcast • All Rights Reserved

The assets you trust most might be the very ones putting your future at risk.   In this episode, I sit down with Camille Scott Wiles, a former ICU nurse turned financial strategist, who reveals how she rebuilt her life and legacy using precious metals, life insurance, and annuities. After losing both parents within 19 hours and weathering the 2008 crash, Camille developed a strategy that helps everyday professionals protect and grow wealth, without Wall Street risk.   If you're looking for security beyond the stock market, this one's for you. 00:00 – From ICU to Investing: Camille's Journey & Why She Left Nursing   06:30 – Generational Wealth Lost: The Real Story Behind the “Silver Spoon”   12:00 – Real Estate to Resilience: Pivoting After the 2008 Crash   18:00 – Life After Loss: Becoming the Matriarch at 30   22:00 – Precious Metals 101: Why Silver is Her #1 Wealth Strategy   28:00 – Borrowing Against Gold: Accessing Liquidity Without Selling Assets   33:00 – Hidden Dangers of Traditional Retirement Plans (401ks, IRAs)   40:00 – Tax-Free, Risk-Free Retirement: Life Insurance & Annuity Strategies for Everyone  

Rooted in Care: Jamie Kitchel on Midwifery, Postpartum Mental Health, and Building a New Model for Mothers | Conversations with a Chiropractor Episode Description: What if we treated postpartum care as the beginning—not the end—of a woman's wellness journey? In this deeply personal and enlightening conversation, Dr. Stephanie Wautier sits down with Jamie Kitchel, certified nurse midwife and co-founder of Rooted, a postpartum education and home visiting service in Marquette, Michigan. From the ICU to home births, Jamie's path has been anything but ordinary. She opens up about her early days in critical care, her calling into midwifery, and how three women with nine kids between them decided to reimagine postpartum support from the ground up. They talk about the overlooked emotional toll of new motherhood, the gaps in our medical system, and the importance of meeting families right where they are—at home.

Granulomatosis with Polyangiitis (GPA) – Recognition and Management in the ED Hosts: Phoebe Draper, MD Brian Gilberti, MD https://media.blubrry.com/coreem/content.blubrry.com/coreem/GPA.mp3 Download Leave a Comment Tags: Rheumatology Show Notes Background A vasculitis affecting small blood vessels causing inflammation and necrosis Affects upper respiratory tract (sinusitis, otitis media, saddle nose deformity), lungs (nodules, alveolar hemorrhage), and kidneys (rapidly progressive glomerulonephritis) Can lead to multi-organ failure, pulmonary hemorrhage, renal failure Red Flag Symptoms: Chronic sinus symptoms Hemoptysis (especially bright red blood) New pulmonary complaints Renal dysfunction Constitutional symptoms (fatigue, weight loss, fever) Workup in the ED: CBC, CMP for anemia and AKI Urinalysis with microscopy (hematuria, RBC casts) Chest imaging (CXR or CT for nodules, cavitary lesions) ANCA testing (not immediately available but important diagnostically) Management: Stable patients: Outpatient workup, urgent rheumatology consult, prednisone 1 mg/kg/day Unstable patients: High-dose IV steroids (methylprednisolone 1 g daily x3 days), consider plasma exchange, cyclophosphamide or rituximab initiation, ICU admission Conditions that Mimic GPA: Goodpasture syndrome (anti-GBM antibodies) TB, fungal infections Lung malignancy Other vasculitides (EGPA, MPA, lupus)

Today we are talking to a pulmonary and critical care doc who is returning to the podcast for a second interview. He has achieved several milestones including paying off his student loans and becoming a millionaire. This doc also had a big health scare that landed him in the ICU for a week with a 6 week recovery after he got out of the hospital. He shares how grateful he was to have his financial life in order so he could focus on recovery. He expresses deep gratitude to everyone who took care of him and helped him get healthy again. After the interview we are talking about how to know where you stand financially for Finance 101. Are you using multifamily to build long-term wealth? If not, I strongly encourage you to take a look at 37th Parallel Properties. They are multifamily specialists with a 100% profitable track record across over $1 billion in transaction volume since 2008. Investing with them is like partnering with a highly tax-advantaged family office, building an income-producing long-term wealth development platform. With 37th Parallel, you get access to institutional quality assets, conservatively managed, with proven results. Their educational content on Passive Multifamily Investing is also very good. Visit https://37Parallel.com/wci today for more information. The White Coat Investor has been helping doctors, dentists, and other high-income professionals with their money since 2011. Our free personal finance resource covers an array of topics including how to use your retirement accounts, getting a doctor mortgage loan, how to manage your student loans, buying physician disability and malpractice insurance, asset allocation & asset location, how to invest in real estate, and so much more. We will help you learn how to manage your finances like a pro so you can stop worrying about money and start living your best life. If you're a high-income professional and ready to get a "fair shake" on Wall Street, The White Coat Investor is for you! Have you achieved a Milestone? You can be on the Milestones to Millionaire Podcast too! Apply here: https://whitecoatinvestor.com/milestones  Find 1000's of written articles on the blog: https://www.whitecoatinvestor.com  Our YouTube channel if you prefer watching videos to learn: https://www.whitecoatinvestor.com/youtube  Student Loan Advice for all your student loan needs: https://studentloanadvice.com  Join the community on Facebook: https://www.facebook.com/thewhitecoatinvestor  Join the community on Twitter: https://twitter.com/WCInvestor  Join the community on Instagram: https://www.instagram.com/thewhitecoatinvestor  Join the community on Reddit: https://www.reddit.com/r/whitecoatinvestor  Learn faster with our Online Courses: https://whitecoatinvestor.teachable.com  Sign up for our Newsletter here: https://www.whitecoatinvestor.com/free-monthly-newsletter 

This week on Critical Care Time, we're turning the mic over to you, our brilliant listeners! In this special Q&A episode, Nick and Cyrus read your comments, tackle your toughest clinical questions, and share how your insights have sent them diving back into PubMed, Reddit, and beyond. Whether you're commuting, charting, or on break in the ICU, this episode is packed with practical pearls, literature deep-dives, and the human stories that make critical care so rewarding. Thank you for helping us learn and grow—let's jump right in! Hosted on Acast. See acast.com/privacy for more information.

What happens when a full-time ICU nurse, deep in burnout, poor sleep, and feeling uncomfortable in his own body… decides enough is enough? In this powerful episode of the Breakthrough Series, we sit down with Nathaniel—a DNP in progress, critical care nurse, and now fitness success story. After gaining weight during the pandemic and feeling stuck in the cycle of exhaustion, Nathaniel joined our Metabolic Burn System and committed to a new standard for his health. What followed? → 15 lbs of fat gone. → Energy rebuilt. → Chronic back pain reduced. → And a 5K finish—without training. This isn't just about weight loss. It's about learning self-leadership, building habits that stick through life transitions (including moving states and working long shifts), and breaking free from the perfectionist mindset that keeps so many nurses from ever starting. Nathaniel shares: How he overcame inconsistency and self-doubt Why 80/20 nutrition helped him stop bingeing and enjoy food again How journaling, community, and small shifts created big wins And what he'd tell any nurse stuck in the “all or nothing” mindset

I wanted to share something really personal with you—my keynote presentation from the AWHONN Convention in Orlando, FL. In this talk, I open up about two moments that completely changed my life: being banned from donating blood in nursing school for being gay, and having my first panic attack after a long shift in the ICU.These moments could've broken me. But instead, they lit a fire. One pushed me to start Banned4Life and help lift the FDA's gay blood ban. The other led me to create my Nurse Blake social media accounts as a way to share my story & overcome burnout. Life gives us moments—some beautiful, some painful, some totally unexpected. My hope is that as you listen, you'll look at your own defining moments and realize: they don't have to hold you back. You have the power to take them, shape them, and turn them into something meaningful.___________I hope to see you later this Fall during my But Did You Die? Comedy Tour! Tickets on sale now at: nurseblake.com ___________I want to shoutout AWHONN for selecting me to be their Keynote and to everyone who attended my session!

Every other week I'm republishing one of my most popular or impactful episodes and adding an update, new insight, or context that will help you benefit from it even more. This week I'm highlighting Episode 236, which highlights some key medical terms that you might not yet know. And, if you're like me, your confidence goes way up when you actually understand what people are talking about. Imagine that! When I was a student (and new nurse) I remember hearing medical terms all the time that would make me think, “I should probably know what that means, but I'm too embarrassed to ask.” And I hated how that made me feel… lost, incompetent, out of the loop, and unsure of myself. You can imagine what feeling this way did to my confidence level. Yep…pretty low sometimes. In this episode I'm diving into some common medical terms that students (and even experienced nurses) often feel a little unsure about…terms like: Sensitivity vs specificity Hypoxia vs hypoxemia Crystalloid vs colloid And let's not forget medical slang like “the gap,” “rainbows,” and “Christmas trees” After listening to this episode, you'll be absolutely fascinating at your next cocktail party and probably feel a lot more confident at the bedside, too! Full Transcript - Read the article and view references FREE CLASS - If all you've heard are nursing school horror stories, then you need this class! Join me in this on-demand session where I dispel all those nursing school myths and show you that YES...you can thrive in nursing school without it taking over your life! Crucial Concepts Bootcamp - Start nursing school ahead of the game, or reset after a difficult first semester with my nursing school prep course, Crucial Concepts Bootcamp. Learn key foundation concepts, organization and time management, dosage calculations, and so much more. Kali Dayton Interview: Learn about ICU delirium and the dangers of oversedation in this compelling interview. Purewick:  This is an external catheter that's gaining quickly in popularity (you know, if there were a popularity contest amongst urine collection devices). Episode 89: Explore oxygenation (especially if the concept of hypoxemia vs hypoxia is new to you!). Episode 64: Learn more about atelectasis (spoiler alert…it's so much more than “crackles!”)

The fun didn't end last week, the convo was so good we have a part 2!ICU nurses Lindsey Shelton and Jason Wolf keep the convo going for the second half of their raw, hilarious catch up. Opening up about navigating weird patient encounters and reading new grad stories while sharing a few of their own!To balance it out, they go deeper on life after leaving toxic jobs, what's changed (or hasn't) in the nursing world, and how they're using their platforms to advocate, cope, and connect.They unpack:Burnout & Boundaries – What they wish they knew before hitting the wallGoing Viral – The good, bad, and ridiculous of nursing TikTok fameNurse Identity – Who are you after leaving the bedside?Toxic Positivity – Why it's okay not to be okay, even onlineHumor as Healing – The power of laughing at the worst momentsMore stories, more honesty, and even more reasons to laugh-cry and potentially chuck your stethoscope at someone. Follow us on IG: The Guest: @sir_master_wolfThe Pod: @friends.and.enemasThe Host:  ⁨@scrubhacks⁩ 

Mandy Rhea and Aaron Berg join Ralph Sutton and Dov Davidoff and discuss Ralph switching from Samsung to an iPhone for a week, Mandy Rhea going from ICU nurse to the adult entertainment industry and more before they play the fan favorite SDR gameshow Wish On Her List where the guys have to guess if each item shown to them is on Mandy Rhea's Amazon Wishlist resulting in drinking and clothing removal!(Air Date: June 18th, 2025)Support our sponsors!YoKratom.com - Check out Yo Kratom (the home of the $60 kilo) for all your kratom needs!To advertise your product or service on GaS Digital podcasts please go to TheADSide.com and click on "Advertisers" for more information!You can watch The SDR Show LIVE for FREE every Wednesday and Saturday at 9pm ET at GaSDigitalNetwork.com/LIVEOnce you're there you can sign up at GaSDigitalNetwork.com with promo code: SDR for discount on your subscription which will give you access to every SDR show ever recorded! On top of that you'll also have the same access to ALL the shows that GaS Digital Network has to offer!Follow the whole show on social media!Mandy RheaTwitter: https://twitter.com/HotMomMandyInstagram: https://instagram.com/TheRealMandyRheaRalph SuttonTwitter: https://twitter.com/iamralphsuttonInstagram: https://www.instagram.com/iamralphsutton/Aaron BergTwitter: https://twitter.com/aaronbergcomedyInstagram: https://instagram.com/aaronbergcomedyDov DavidoffTwitter: https://twitter.com/DovDavidoffInstagram: https://instagram.com/DovDavidoffShannon LeeTwitter: https://twitter.com/IMShannonLeeInstagram: https://instagram.com/ShannonLee6982The SDR ShowTwitter: https://twitter.com/theSDRshowInstagram: https://www.instagram.com/thesdrshow/See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

"It was dark, and I remember looking over the ledge thinking, 'What's down there?' I probably don't want to know…" Deirdre Keane has never encountered an adventure she didn't want to pursue. The pediatric ICU nurse turned McKinsey consultant is always on the run, whether it's at a world marathon major or it's completing — and winning! — the World Marathon Challenge, running seven marathons in seven days on seven continents. Deirdre's latest endorphin chase: the Everest Extreme Ultra Marathon! In this conversation, she talks about the three-week excursion traversing glaciers and mountain passes and, ultimately, an unplanned trek back to base camp. Warning: This episode may inspire you to go do something big, scary, and life-changing.  SPONSOR:  New Balance: Click here to shop the just-released New Balance FuelCell Rebel v5! In this episode: Deirdre's introduction to the Everest Extreme Ultra Marathon, and how she was able to make it happen (4:00) Deirdre's lasting relationships with her World Marathon Challenge crew (7:30) How Deirdre planned to complete the Everest Extreme Ultra Marathon, and what her training was like (9:00) The logistical components of the Everest Extreme Ultra Marathon (17:20) Deirdre's adventures before the ultra, summitting Island Peak (21:45) What it was like seeing Mount Everest for the first time (36:20) All about the Everest accommodations (41:00) Deirdre talks about completing the Everest Extreme Ultra Marathon (45:30) On finishing the Everest Extreme Ultra Marathon — and the road away from the mountain (58:40) Deirdre's top takeaways from this experience (1:08:40) What's next on the run for Deirdre (1:10:40) Follow Ali: Instagram @aliontherun1 Join the Facebook group Support on Patreon Subscribe to the newsletter SUPPORT the Ali on the Run Show! If you're enjoying the show, please subscribe and leave a rating and review on Apple Podcasts. Spread the run love. And if you liked this episode, share it with your friends!

Given her vast array of expertise, Gabby Windey takes her guests on a deep dive into the topics today's audiences care about: dating (duh), sexuality (hell yes), health & mental health (ugh so important) plus a healthy dose of pop culture shit talk.Each episode, Gabby will be interviewing guests with the ultimate goal to break down walls and get beyond the typical interview questions— “So tell us about yourself” doesn't actually tell us anything about who the person really is- does it?! Instead, she skips the surface and plunges right into the core. Drawing from her experience as an ICU nurse, NFL cheerleader, and being The Bachelorette- Gabby is able to bring a unique perspective to each conversation. With discussions covering serious and relatable topics but approached from relatability and heart (along with Gabby's wicked sense of humor— of course).See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.