Podcasts about Dosing

Send us a textHere is a supplement company Move Daily Fitness supports and where we get our product: Legion Athletics Supplements *This is an affiliate link. Discount code is MoveDaily Dr. Allan Bacon discusses the efficacy of supplements, how to source reputable companies, emphasizing the importance of reading labels and avoiding redundant products.00:01 Understanding dietary supplements, particularly for menopausal women.07:36 Reading supplement labels, and warning labels15:15 Is collagen worth the hype?22:53 Protein powders30:30 BCAA's and EAA's38:10 Creatine monohydrate and creatine hydrochloride45:48 Dosing creatine53:25 ProbioticsFollow Dr Allan Bacon:https://mauiathletics.com/Instagram: @drallanbacon Indemnity** All information provided by Move Daily Fitness and Tracy Steen is of a general nature and is furnished for educational/entertainment purposes only. No information is to be taken as medical or other health advice pertaining to any individual's specific health conditions. Move Daily is not engaged in rendering any medical services. Move Daily makes no guarantee regarding the accuracy, timeliness or relevance of any text, video or audio content. Any content provided is not a diagnosis, treatment plan or recommendation for a particular course of action regarding your health and it is not intended to provide specific medical advice. Do not delay in seeking the advice and diagnosis of a medical professional because of anything you may have read or interpreted from Move Daily Fitness content.  Consult your health care professional before participating in or acting on any recommendations found on Move Daily Fitness.  You agree, at your exposure, to indemnify and hold Move Daily Fitness and Tracy Steen harmless from any and all losses, liabilities and injuries, or damages resulting from and all claims, cause of action, suits, proceedings and demands against Move Daily Fitness and Tracy Steen, arising from or related to decisions or recommendations you make using Move Daily Fitness content. You agree that use of this information is at your own risk.Shop Legion Supplements and use discount code: MoveDailyThis is an affiliate link. The Move Daily Membership is a paid monthly subscription for women, which gives you access to a huge amount of resources to help support you in reaching your health goals. Whether you're looking to lose fat, gain lean muscle, focus on your nutrition, give time to wellness or simply wish to dial in your overall health, we can support you in achieving your objectives. Join today!Support the showThanks for moving daily with us in your fitness, wellness and nutrition! Be sure to follow us here:YouTube: https://www.youtube.com/@TracySteenMoveDailyInstagram: https://www.instagram.com/movedailyfitness/Facebook: https://www.facebook.com/tracy.steen1TikTok: https://www.tiktok.com/@tracysteenSubscribe to my podcast! https://www.buzzsprout.com/2375873/support

In this episode of the PFC Podcast, the discussion revolves around patient positioning during procedural sedation, the pharmacology and application of Versed (Midazolam), and the nuances of dosing in various clinical scenarios. The speakers emphasize the importance of having a plan for airway management, the physiological implications of patient positioning, and the amnestic effects of Versed in trauma and surgical settings. They share insights from their experiences in austere environments, highlighting the need for adaptability and careful consideration of patient responses to sedation. In this conversation, the speakers delve into the complexities of IV amnestics, particularly focusing on Propofol and Midazolam, and the challenges faced during sedation in anesthesia. They discuss the importance of monitoring patient comfort, the nuances of sedation versus analgesia, and the implications of using drugs like Ketamine and Versed. The conversation highlights the critical nature of assessing patient responses and the difficulties in managing sedation effectively, emphasizing that sedation is often more challenging than general anesthesia.TakeawaysPatient positioning is crucial during procedural sedation.Recovery position may enhance airway protection during sedation.Always have a plan for airway management in different positions.Versed is a GABA agonist that promotes sedation and amnesia.Dosing of Versed varies significantly based on patient condition.In trauma cases, lower doses of sedatives may be necessary.Communication with the patient is key when administering sedatives.Understanding the pharmacodynamics of Versed aids in effective use.Amnestic effects of Versed can be dose-dependent.Clinical experience plays a significant role in medication administration. IV amnestics like Propofol and Midazolam do not have a guaranteed amnestic dose.Sedation is one of the most challenging aspects of anesthesia.Monitoring vital signs is crucial during sedation to assess patient comfort.The physiological state of the patient significantly affects drug dosing.Ketamine is not considered an amnestic drug by some providers.Patient comfort is paramount, and sedation must be carefully managed.The use of narcotics can help manage discomfort during sedation.Understanding the patient's history, such as alcohol use, is important for dosing.Sedation requires constant assessment and adjustment of medications.The complexities of sedation often make it more difficult than general anesthesia.Chapters00:00 Introduction to Patient Positioning in Procedural Sedation09:57 Understanding Versed: Mechanism and Usage19:54 Dosing Strategies for Versed in Different Patient Scenarios29:54 Amnestic Effects and Clinical Considerations of Versed35:05 Understanding IV Amnestics: Propofol and Midazolam39:01 The Challenges of Sedation in Anesthesia45:26 Monitoring and Assessing Patient Comfort During Sedation51:27 Navigating the Complexities of Sedation and Analgesia57:55 The Role of Versed and Ketamine in Anesthesia01:01:39 Final Thoughts on Sedation Practices and Patient SafetyThank you to Delta Development Team for in part, sponsoring this podcast.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠deltadevteam.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠For more content, go to ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠www.prolongedfieldcare.org⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Consider supporting us: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠patreon.com/ProlongedFieldCareCollective⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ or ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠www.lobocoffeeco.com/product-page/prolonged-field-care⁠

I'm excited to share my conversation with Dr. Scott Sherr, where we dive deep into methylene blue - a compound you've probably seen all over social media lately (those blue tongues!). As someone whose primary research focuses on Alzheimer's disease, I was fascinated to explore the science behind this molecule that dates back to the 1870s and was actually the first drug registered with the FDA in 1897.  The most fascinating insight for me was learning how methylene blue can serve as an electron acceptor in our mitochondria - essentially functioning as a substitute for oxygen when our cells are under stress. This explains why it shows promise for everything from traumatic brain injury to cognitive enhancement and even as a potential alternative to stimulant medications.   If you're interested in optimizing brain performance, understanding mitochondrial health, or simply curious about this blue compound that's suddenly everywhere, this episode provides both the scientific foundation and practical applications you need. Subscribe to The Neuroscience Experience for more conversations at the intersection of brain science and performance. I'm committed to bringing you evidence-based insights that you can apply to your own health journey.  SponsorsA huge thank you to my sponsors for supporting this episode. Check them out and enjoy exclusive discounts:Hone Health – Take control of your hormones with at-home testing designed specifically for men. Get personalized insights and expert guidance to optimize your health and performance. Learn more at: https://honehealth.com/Momentous – Science-backed supplements trusted by elite athletes and experts. Whether you're looking to improve recovery, performance, or overall wellness, Momentous has you covered. Use code NEURO for 20% off your order: https://www.livemomentous.com/neuroTroscriptions – Unlock your cognitive potential with precision-dosed nootropics developed by medical experts. Whether you need more focus, clarity, or energy, Troscriptions offers innovative solutions.- Get 10% off: https://troscriptions.com/NEURO- https://troscriptions.com/discount/NEUROMAIL?utm_source=affiliate&utm_medium=email&utm_campaign=NeuroMailTimestamps 00:00 Introduction 02:30 Methylene Blue's Role in Neurotransmitter Regulation 07:54 Mitochondrial Health and Methylene Blue 17:02 Methylene Blue and Modern Health Challenges 25:27 Methylene Blue in Hypobaric and Hyperbaric Environments 29:47 Understanding Hyperbaric Oxygen Therapy 32:27 Methylene Blue: A Mitochondrial Rescue 36:52 Bioavailability of Methylene Blue 42:17 Dosing and Applications of Methylene Blue 47:46 Combining Methylene Blue with Other Treatments 54:02 Conclusion and Further ResourcesThe Neuro Athletics Newsletter Instagram: @louisanicola_Twitter : @louisanicola_YouTube: @Louisa NicolaThe Neuro Experience Podcast is proud to have hosted: Dr Andrew Huberman, Dr Gabrielle Lyon, Dr Layne Norton, Thomas DeLauer, Shawn Stevenson, Dr. Rocio Salas-Whalen, Saad Alam, Uma Naidoo, Dr. Lanna Cheuck, Angela Lee Pucci, Jillian Turecki, Dr. Jordan Feigenbaum, Dr. Darren Candow, Dr. Sue Varma, Evy Poumpouras, Dr Casey Means, Renee Deehan, Dr Chris Palmer, Dr Charles Brenner, Dr Joe Zundell, Dr Ray Dorsy, Dr Dale Bredeson, Dr. Ben Bikman

Episode Highlights with McCall McPhersonHow GLPs were developed and how they became popular for weight lossWhat GLPs actually are and how they work The inflammatory pieces related to GLP use and her theory that they may reduce inflammationInflammation is a common factor in chronic disease but tough to pinpoint and affect, though easy to testShe measures HS-CRP on labs to check inflammation How she is seeing a consistent reduction in autoimmune antibodies with GLPsWhat to know about muscle loss with GLPs and how to maintain muscle mass if you take them: eat enough protein and strength-building activity Heart disease kills more people than all cancers combined A couple of important studies looking at cardiovascular death risk for diabetics on GLPs - 51% risk reduction with GLP useThe select trial in non-diabetics found a 21% reduction in heart attack and stroke risk with GLPsHow being undernourished and underhydrated can impact metrics like HRV and resting heart rate if people don't drink enough water on thisThe real data about thyroid risk and why this is really important to understand Dosing is so important and overdosing is responsible for the majority of issuesResources MentionedModern Weight Loss's: GLP-1's Decoded Guide McCall McPherson's website

Send us a message with this link, we would love to hear from you. Standard message rates may apply.The meteoric rise in demand for weight loss drugs has created widespread shortages, leading to the emergence of compounding pharmacies as an alternative source for these medications.• Compounding pharmacies create custom medications by combining, mixing, or altering ingredients to meet specific needs• Unlike FDA-approved medications, compounded drugs don't undergo the same rigorous safety and effectiveness reviews• Dosing errors with compounded weight loss medications have led to serious adverse events requiring hospitalization• Confusion between units, milliliters, and milligrams contributes to potentially dangerous dosing mistakes• Some compounding pharmacies add unproven ingredients like vitamins, L-carnitine, and NAD to their formulations• The long half-life of these medications (about one week) means overdose symptoms can persist for extended periods• Pharmaceutical companies have responded with direct-to-consumer models offering FDA-approved versions at reduced prices• Eli Lilly now offers Zepbound in vial form for approximately $499/month versus $1000+ for pen versions• Novo Nordisk's NovaCare pharmacy provides direct-to-patient delivery of Wegovy single-dose pens at similar price pointsPlease talk to your healthcare provider about what option might be right for you, as these medications require careful consideration and proper dosing is essential for safety.Support the showProduction and Content: Edward Delesky, MD & Nicole Aruffo, RNArtwork: Olivia Pawlowski

Adenosine is the first IV medication given to stable patients with sustained supraventricular tachycardia (SVT) refractory to vagal maneuvers. Symptoms indicating a stable vs unstable patient. Common causes of tachycardia. Cardiac effects of Adenosine. Indications for use in the ACLS Tachycardia algorithm.Considerations and contraindications. Adenosine as a diagnostic for patients in A-Fib or A-Flutter with RVR.Dosing and administration.Other podcasts that cover common ACLS antiarrhythmics in more detail and another covering Brugata Criteria used to differentiate V-Tach from SVT with an aberrancy, can be found on the Pod Resources page at passacls.com.Connect with me:Website: https://passacls.com@Pass-ACLS-Podcast on LinkedInOther Links: Buy Me a Coffee at https://buymeacoffee.com/paultaylor Practice ECG rhythms at Dialed Medics - https://dialedmedics.com/Save money on prescription medications for you and your pets: https://nationaldrugcard.com/ndc3506*Commissions may be earned from the above links.Good luck with your ACLS class!

In this episode of the Smarter Not Harder Podcast, Bracha Banayan, a seasoned healthcare professional and innovator in weight management, uncovers the untold truths behind GLP-1 drugs like Ozempic, Wegovy, and their competitors. Bracha shares her personal journey from battling unexpected weight gain to discovering how these medications can not only help with weight loss but also transform overall health by reducing inflammation, moderating blood sugar spikes, and even rewiring behavior through what she calls the “pause factor.” She also dives into the science, the art of proper dosing, potential side effects, and the critical role of lifestyle modifications and supportive ecosystems in achieving long-term success. Join us as we delve into: How GLP‑1 drugs work to slow gastrointestinal transit, moderate blood sugar spikes, and influence our brain's reward system The concept of the “pause factor” and how a delay in instant gratification can transform eating habits Dosing strategies—from starting low and titrating gradually to minimizing side effects while achieving sustainable weight loss The critical role of lifestyle modifications, including nutrition, exercise, and behavioral coaching, in complementing GLP‑1 therapy This episode is for you if: You're curious about innovative, medication-assisted approaches to weight management You want to understand the science behind GLP‑1 drugs beyond appetite suppression You're interested in learning how proper dosing and lifestyle changes can lead to long-term health benefits You're a healthcare professional or patient seeking a holistic and informed approach to obesity management You can also find this episode on… YouTube: https://youtu.be/edjn6024DGc Find more from Bracha Banayan: IVDRIPS: https://ivdrips.com/ HastyMeds: https://ivdrips.com/hastymeds Instagram: https://www.instagram.com/bracha_banayan/ LinkedIn: https://www.linkedin.com/in/bracha-banayan/ Find more from Smarter Not Harder: Website: https://troscriptions.com/blogs/podcast | https://homehope.org Instagram: @troscriptions | @homehopeorg Get 10% Off your purchase of the Metabolomics Module by using PODCAST10 at https://www.homehope.org Get 10% Off your Troscriptions purchase by using POD10 at https://www.troscriptions.com Get daily content from the hosts of Smarter Not Harder by following @troscriptions on Instagram.

⚠️ Disclaimer: This episode contains discussions about cannabis use, consumption methods, and its relationship with mental health and motherhood. This content is for educational and informational purposes only and is not intended as medical advice. Please consult a healthcare professional before making any health or lifestyle changes.In this fascinating and educational conversation, Mary Hendricks and Riley Kirk, a cannabis educator and scientist, dive deep into the realities, myths, and stigmas surrounding cannabis use, particularly in the context of motherhood, mental health, and wellness.They explore the differences between edibles, vaporization, and smoking, the importance of terpenes in cannabis effects, and how dosing plays a crucial role in having a positive experience. Mary and Riley also discuss the stigma surrounding cannabis use, the challenges of discussing it with medical professionals, and why education is the key to responsible and informed consumption.The episode also covers legal considerations, product safety, and common misconceptions about Delta-8, THCA, and other cannabis products that have gained popularity. If you're curious about how cannabis fits into motherhood, mental health management, or everyday wellness, this episode provides a judgment-free, research-backed conversation to help break down the barriers of stigma.

In this episode of the Longevity Podcast, I'm thrilled to be joined by industry innovator Michael Antonelli, Founder & CEO of Healthgevity. Together, we dive deep into cutting-edge strategies for optimizing metabolism, muscle health, and immunity.  Try Healthgevity and use promo code: NAT10.   What We discuss: Michael Antonelli's background and journey ... 00:07:41 The inspiration behind Healthgevity ... 00:10:24 Introduction to metabolic health ... 00:19:16 Discussion on Ignite 2.0 formulation ... 00:20:16 Dosing flexibility of Ignite 2.0 ... 00:23:48 DNF10 and its role in Ignite 2.0 ... 00:30:10 Building muscle with longevity supplements ... 00:31:09 Introduction to PeptiStrong and its benefits ... 00:32:33 The importance of gut health and immunity ... 00:41:43 Prime Gut Health formula details ... 00:42:15 Discussion on Biorepair ... 00:55:56 Introduction to Immuno Reboot ... 01:00:37 Importance of sleep and Serenity product ... 01:02:26 Details on Serenity formulation ... 01:05:00 Conclusion and where to find Healthgevity products ... 01:11:37   Our Amazing Sponsors: Young Goose L.A.D.R. Serum -  Powered by light-activated DNA repair enzymes, NAD+, and collagen peptides, it reverses damage while you go about your life. Sunlight? Red light therapy? It all helps this serum work smarter, not harder. Visit YoungGoose.com—use code NAT10 to get started, or 5NAT if you're an existing customer. Future-proof your face.   Quantum Upgrade - Imagine plugging yourself into a limitless power source. It's been rigorously tested and shown to improve blood flow, reduce stress, and boost cellular energy by up to 29%. Try it today at quantumupgrade.io/NAT and start running life, instead of life running you. Use code NAT10 to get a 15-day free trial on the All-in-One Frequency Bundle. Good through June 1st, 2025.   Wizard Sciences (Neural Rx) - Neural Rx isn't just about a quick boost. It's designed to protect your brain long-term. With C60 (an antioxidant) and anti-inflammatory benefits, it combats oxidative stress and helps keep those brain cells healthy and happy. Plus, it supports mitochondrial efficiency, meaning more energy and focus for the long haul. Use code NAT15 at checkout to get 15% off your purchase. Visit wizardsciences.com.   Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

I have been practicing regenerative medicine for nearly two decades, and I don't know why it hasn't taken off like I expected. I asked that question to Dr David Karli why he believes that is the case, and what he is doing to pioneer new techniques that produce better outcomes. This is a deep-dive, technical episode about the art and science of regenerative medicine, and in which situations it is the most appropriate model of care.Dr. David Karli is a renowned leader in the field of Regenerative Medicine. He is an internationally known physician entrepreneur and respected author and lecturer in the field, having dedicated over twenty years of his life to perfecting life altering orthobiologic procedures for his patients. Many of his patients are long standing and travel thousands of miles to seek his care. He opened the Karli Center in March 2023 in Miami to create a focused resource, specifically devoted to advancing and delivering biological therapies, easily accessible to both national and international patients.Join us as we explore:Clearing up the confusion around regenerative medicine - what it is, what's the goal, why it hasn't taken off like I believe it should and Dr Karli's practice of the art.Cellular dosing - what is is, how it works and why it is at the center of the Karli Center.Why it is misguided to to spend thousands and thousands on biohacking and therapies but you are not putting your OWN cells to work for you.Whether the meniscus can be regenerated.How functional medicine and regenerative medicine are going to intersect.Contact: Website - https://www.karlicenter.comSupport the showFollow Steve's socials: Instagram | LinkedIn | YouTube | Facebook | Twitter | TikTokSupport the show on Patreon:As much as we love doing it, there are costs involved and any contribution will allow us to keep going and keep finding the best guests in the world to share their health expertise with you. I'd be grateful and feel so blessed by your support: https://www.patreon.com/MadeToThriveShowSend me a WhatsApp to +27 64 871 0308. Disclaimer: Please see the link for our disclaimer policy for all of our content: https://madetothrive.co.za/terms-and-conditions-and-privacy-policy/

In the second edition of a special podcast series, CancerNetwork® spoke with Daniel Morgensztern, MD; Mary Ellen Flanagan, NP; and Janelle Mann, PharmD, BCOP, about the best practices for incorporating recently approved bispecific antibodies into cancer care. This discussion focused on clinical trial results, administration protocols, and adverse effect (AE) management strategies related to the use of tarlatamab-dlle (Imdelltra) for patients with small cell lung cancer (SCLC). Morgensztern is a professor of Medicine and the clinical director of Thoracic Oncology in the Division of Oncology at Washington University School of Medicine in St. Louis. Flanagan is a nurse practitioner in the Division of Thoracic Oncology at Washington University. Mann is a clinical oncology pharmacist at Siteman Cancer Center of Washington University School of Medicine and manager of Clinical Pharmacy Services at Barnes-Jewish Hospital. The conversation opened with Morgensztern highlighting tarlatamab's mechanism of action as an agent that targets DLL3. He then reviewed prior efficacy data that the therapy demonstrated in the phase 1 DeLLphi-300 trial (NCT03319940) and the phase 2 DeLLphi-301 trial (NCT05060016). Of note, the FDA approved tarlatamab as the first available T-cell engager immunotherapy for patients with extensive-stage SCLC who have progressed on prior platinum-containing chemotherapy in May 2024 based on data from the DeLLphi-301 trial. Additionally, Flanagan detailed strategies for monitoring and mitigating the most common AEs associated with tarlatamab in this patient population, which include cytokine release syndrome and immune effector cell–associated neurotoxicity syndrome. Mann then outlined considerations for properly dosing and administering the agent, highlighting factors that clinicians should keep in mind when continuing treatment in an inpatient or outpatient setting. The group also spoke about clinical decision-making related to patients who have brain metastases, which included processes for adjusting the dose of tarlatamab and sequencing the bispecific agent with radiotherapy. Reference FDA grants accelerated approval to tarlatamab-dlle for extensive stage small cell lung cancer. News release. FDA. May 16, 2024. Accessed March 14, 2025. https://tinyurl.com/48k34rw5

Get My Book On Amazon: https://a.co/d/avbaV48Download The Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/In this Q&A video, I dive deep into your peptides questions—from dosage comparisons and injection techniques to protocol stacks for endurance, recovery, muscle growth, and even hormone optimization.Below are the exact timestamps with each question I answered:0:00 – [Music Introduction]0:10 – Introduction & overview of the Q&A session1:59 – Five Amino 1 MQ: Liquid vs Pills Dosage Comparison3:02 – Peptide and Supplement Protocol for Endurance Events (50k, 50 mile, 100 mile)5:01 – SLU PP332: Injectable vs Oral – Which Is Better?5:20 – Best Peptides for Jiu-Jitsu Performance, Endurance, and Recovery6:22 – SLU PP332 Dosage for Endurance: When to Take It?7:16 – Best Stack for Pre and Post Training for Endurance and Performance8:14 – Best Way to Inject: Intramuscular vs Subcutaneous for Different Peptides9:01 – How to Inject If You Have Very Little Body Fat Left9:51 – Mixing Instructions for Pinealon10:15 – Reconstituting and Dosing a Blend of GHK, TB500, and BPC 15710:54 – Is Pre-loading Multiple Peptides in the Same Syringe Safe?11:29 – How to Use and Convert Doses with the Autopens12:34 – Which Blood Tests Should You Monitor While Using Peptides?13:12 – Peptides for Injury and Pain Relief14:01 – Best Peptides for Lower Back Pain and Localized Injections15:05 – Best Peptides for Tendon and Ligament Injuries15:18 – Peptides for Nerve Pain/Neuropathy15:58 – Is a BPC 157 Cream Effective for Sports Injuries?17:38 – Are GH Peptides Safe for a 20-Year-Old Baseball Pitcher?18:05 – Peptides for Muscle Growth at Age 20 (Tesmelone, CHC, etc.)18:36 – How to Cycle Off and What's the Best Replacement?19:00 – Optimal Micro Dosing for Matsi with Reatutide19:57 – Best Stack for Muscle Gain in a 45-Year-Old Woman on Tzapatide20:04 – Peptides for Building Muscle in Adults 55+24:03 – Should You Cycle Off GLP-1s or Stay on Them Long Term?26:44 – Why Do GLP-1s Stop Working and How Can You Restart Results?30:14 – Cervodide vs Trptide Ratutide: Similarities and Differences31:34 – Testosterone and High Hematocrit: Is TRT Safe?32:29 – Optimal Testosterone Levels for a 59-Year-Old Man34:02 – Can Adding Low-Dose Estradiol to TRT Improve Libido?34:18 – How Do I Manage RBC Levels on TRT?35:45 – What Can Post-Menopausal Women Take Instead of HGH and Test Cyp?36:00 – Peptides for Hair Regrowth in Women with Male Pattern Hair Loss49:30 – What's the Best Fat Loss Stack for Fasted Cardio?51:05 – How Does Cagrilintide Tide Fit Into Fat Loss Protocols?51:52 – Does BPC 157 in Angiogenesis Increase Cancer Risk?52:46 – Can MOTS-c and L-Carnitine Raise Heart Rate?52:54 – Injectable vs Oral L-carintiine: Which Is Better?53:07 – How to Adjust Dosing for a BPC and TB500 Blend53:44 – What Is SB01 for Degenerative Disc Disease?54:14 – Best Peptides for Lung Health (COPD, Flem, etc.)54:59 – Should You Take Peptides With Food or Before Meals?55:30 – How Can I Make Peptide Injections Less Painful?55:58 – Can BPC 157/TB500 Be Used as a Nasal Spray or an Eye Drop?56:38 – VIP: Nasal Spray vs Subcutaneous Injection – Which Is Better?

Ever wondered why you still feel sluggish despite a "healthy" lifestyle? In this episode, Jeff Hoyt breaks down how environmental toxins silently accumulate in the body & how zeolite acts as a powerful detox magnet. You'll learn the key differences between binders & chelators, common detox mistakes, & how to safely eliminate harmful substances without depleting essential minerals. Find out how & more in today's episode on “The Smarter Way to Detox” Meet our guest Jeff is a wellness enthusiast with the goal of helping people live healthier & happier lives through detox & smart living strategies. His current focus is on helping people effectively & efficiently remove toxic elements from their bodies using natural detox solutions like zeolite Jeff believes that zeolite is one of the most powerful, yet misunderstood & misused supplements on the market, & his goal is to provide education on how to effectively use this amazing tool for health recovery & improvement Thank you to our partners Outliyr Biohacker's Peak Performance Shop: get exclusive discounts on cutting-edge health, wellness, & performance gear Ultimate Health Optimization Deals: a roundup article of all the best current deals on technology, supplements, systems and more Gain mental clarity, energy, motivation, and focus with the FREE Outliyr Nootropics Mini-Course The simple, guided, and actionable Outliyr Longevity Challenge helps you unlock your longevity potential, slow biological aging, and maximize your healthspan Key takeaways Zeolite is a powerful detox agent, but it's often misused Prioritize sleep & use various detox methods like chlorine dioxide to aid recovery & maintain health Oxidative therapies, once avoided, are now seen as beneficial when used responsibly, contrasting with long-term antioxidant use Zeolite works through a swap mechanism, selectively binding toxins while leaving essential nutrients intact Detoxing efficiently involves addressing daily toxins first, allowing the body to naturally release stored toxins Toxins might either cause or result from chronic illness, making efficient detox crucial for health recovery Episode Highlights 5:13 Oxidative vs. Antioxidant Therapies 10:48 Challenges of Detoxing 11:59 The Magic of Zeolite (ZeoCharge) 33:38 Dosing the Detox Magnet Links Watch it on YouTube:  https://youtu.be/Mv4Tg7CwwDg  Full episode show notes: mindbodypeak.com/199 Connect with Nick on social media Instagram Twitter YouTube LinkedIn Easy ways to support Subscribe Leave an Apple Podcast review Suggest a guest Do you have questions, thoughts, or feedback for us? Let me know in the show notes above and one of us will get back to you! Be an Outliyr, Nick

(For Entertainment Purposes only, always seek a qualified professional.) Support: PositiveSarcasm.com/Donate Segment 1: Try Fork-Lyft, not regular Lyft. Segment 2: Is landing safely now an additional fee? Just askin... Segment 3: The world has always conspired, please dose me slowly. FREE STOCKS, IRA, CASH MANAGEMENT: https://a.webull.com/S4xAPPzv9rXFMdF8Q4 Sign up via my referral link now and claim up to 15 FREE stocks! https://j.moomoo.com/00EoSC Trade Stocks and Crypto Reward when you sign up: https://etoro.tw/47OmXMl PositiveSarcasm.com - 2014 Therapy for yourself, for couples, for teens: https://www.betterhelp.com/ If you are completely out of options: https://988lifeline.org/ Wellness guides: Mel Robbins: https://www.youtube.com/@melrobbins Dr. Jordan B Peterson https://www.youtube.com/@JordanBPeterson

In this episode, Sharmeen Roy, PharmD, BCPS, Chief Strategy & Science Officer at DoseMeRx, discusses the power of precision dosing technology in optimizing pharmacy operations and improving patient outcomes. Learn how validated, EHR-integrated software is enhancing clinical efficiency, reducing errors, and personalizing medication management.

Hemogenyx Pharmaceuticals PLC (LSE:HEMO, OTC:HOPHF) CEO Dr Vladislav Sandler talked with Proactive's Stephen Gunnion about the company's recent milestone—the first human dose of its proprietary CAR-T cell therapy, HG-CT-1, for treating relapsed refractory acute myeloid leukemia (AML) in adults. This is a significant development in tackling one of the deadliest blood cancers, which has a low remission rate with current frontline therapies. Sandler explained, “We are trying to cure a very deadly disease which is called acute myeloid leukemia... This is one of the worst blood cancers in existence.” He highlighted that only 30% of newly diagnosed patients respond to frontline therapies, leaving a significant need for more effective treatments. The therapy uses third-generation chimeric antigen receptor (CAR) technology, which, according to Sandler, offers the same efficacy as the current second-generation CARs but with enhanced safety. The company is poised to accelerate its clinical trials, pending resource availability, with the potential to infuse patients every 14 days after the fourth patient. With the first patient showing no adverse effects so far, Hemogenyx is hopeful about the progress of HG-CT-1 and is ready to scale up manufacturing as new patients are identified. For more insightful interviews and the latest updates, visit Proactive's YouTube channel. Don't forget to like the video, subscribe to the channel, and enable notifications for future content. #Hemogenyx #CAR_Therapy #HGCT1 #AML #CancerTreatment #Biotechnology #HealthcareInnovation #ClinicalTrials #BloodCancer #Investing

In this episode of 'The Sleep Edit', we dig into the topic of sleep supplements for children, specifically focusing on melatonin and magnesium. Melatonin and magnesium (and "calm" and "sleep" gummies in general) have become very popular among tired parents, but what is the actual evidence for these supplements? Are they safe? What do parents need to know? Timestamps 00:00 Introduction and Disclaimer 01:09 Welcome Back to the Sleep Edit 01:21 Melatonin and Magnesium: The Two Big Ms 04:24 Understanding Melatonin 06:14 Melatonin's Effects and Usage 09:45 Melatonin for Children: Considerations and Concerns 21:16 Dosing and Safety of Melatonin 28:15 Melatonin Concerns and Parental Thoughts 29:37 Safety and Alternatives to Melatonin 31:28 Introduction to Magnesium for Sleep 34:49 Magnesium's Role and Benefits 36:39 Challenges in Diagnosing Magnesium Deficiency 38:49 Magnesium Supplementation Studies 39:54 Magnesium for Children: Evidence and Recommendations 47:25 Magnesium Lotions and Creams: Fact or Fiction? 53:33 Final Thoughts and Practical Advice 55:44 Conclusion and Additional Resources Links

“Is melatonin bad for you?” is the most common question I get whenever I suggest melatonin.They've heard on a podcast (or read on a blog) the dangers of melatonin.And how you can become addicted to melatonin, wrecking your own body's ability to produce it if you take melatonin supplements.I totally understand the concern – no one wants to shut down their own melatonin production.If you've been convinced that this melatonin side effect is real – you've been duped.And in today's episode, you'll discover WHY this claim is not only false, but physically impossible.For everyone wondering “is melatonin bad for you?,” you're about to discover why melatonin is so powerful and much more than just a sleep aid. Its potential for regulating your body goes far beyond sleep given that it's produced in your skin and your gut.My guest today – Dr. Deanna Minich – has extensively studied melatonin to uncover its hidden potential to transform your health.Deanna Minich, PhD, is a nutrition scientist, educator, and author, with over twenty years of experience in academia and in the natural product industries, currently serving as Chief Science Officer at Symphony Natural Health. She has been active as a functional medicine clinician in clinical trials and in her own practice (Food & Spirit™).She is the author of six books on wellness topics, four book chapters, and over fifty scientific publications. Through her talks, workshops, groups, and in-person retreats, she helps people to transform their lives practically and artfully through nutrition and lifestyle.Today we'll cover a lot of ground so you can get the full picture of melatonin benefits!Let's dive in!In This Episode:What melatonin is and how it's produced in the bodySurprising discovery of melatonin in 1958Melatonin as a potent antioxidantHow melatonin supports brain detox during sleep (impacting neurodegenerative diseases risk)Melatonin role in gut health, immune function, and mitochondria healthIs melatonin bad for you and can melatonin supplements be addictive?Is melatonin in pregnancy safe?Melatonin dosing tipsWhat foods naturally contain melatonin?Quotes“Melatonin is not just a sleep molecule—it's an antioxidant, anti-inflammatory, and neuroprotective powerhouse.” – Dr. Deanna Minich“One molecule of melatonin can quench up to 10 free radicals, making it more potent than vitamin C as an antioxidant.” – Dr. Deanna MinichLinksFind Dr. Minich online | Instagram | FacebookHealthy Skin Show ep. 105: Can Melatonin Help Itchy Skin (So You Can Sleep)?Melatonin and brain barriers: The protection conferred by melatonin to the blood-brain barrier and blood-cerebrospinal fluid barrierMelatonin as a master regulator of cell death and inflammation: molecular mechanisms and clinical implications for newborn careMelatoninMelatonin – RxList

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It is finally time for our long awaited second Q&A episode! We throw questions at each other, though honestly Debbie does answer most of them. Huge thanks to everyone who submitted a question - don't hesitate to send any more you may have to our email address!  Remember, you can get in touch with us via clinical.research.intro@gmail.com. Please feel free to send questions, comments and compliments for Elyse to read out on the pod. It's fun to make Debbie squirm! Credit to our friend Sam Winnie for their awesome and cute music. Check out their work at https://www.samwinnie.com/ Resources: Revolutionizing healthcare: the role of artificial intelligence in clinical practice -https://bmcmededuc.biomedcentral.com/articles/10.1186/s12909-023-04698-z Dosing by weight and the morning after pill - https://pmc.ncbi.nlm.nih.gov/articles/PMC4500687/  https://accpjournals.onlinelibrary.wiley.com/doi/abs/10.1002/j.1875-9114.2012.01108.x#:~:text=Dosing%20based%20on%20body%20weight,not%20increase%20with%20body%20size.

Please note: This episode was recorded before the LA WildfiresThe guys sit down with comedian, podcaster, and expert skier Chelsea Handler to discuss her new book I’ll Have What She’s Having and whether men’s volleyball exists. Plus, does Gavin have a weird morning routine? See omnystudio.com/listener for privacy information.

Drs. Henry “Chip” Chambers and Warren Rose join Dr. Megan Klatt to tackle rifampin dosing for gram-positive infections. In this episode, they break down rifampin synergy studies and discuss what is the optimal dosing of rifampin for challenging gram-positive bacterial cases, in particular Staphylococcus aureus infections with or without retained hardware/devices.   Listen to Breakpoints on iTunes, Overcast, Spotify, Listen Notes, Player FM, Pocket Casts, TuneIn, Blubrry, RadioPublic, or by using our RSS feed: https://sidp.pinecast.co/ References: Deconstructing the Dogma: Systematic Literature Review and Meta-analysis of Adjunctive Gentamicin and Rifampin in Staphylococcal Prosthetic Valve Endocarditis. Open Forum Infect Dis. 2022 Oct 31;9(11):ofac583. doi: 10.1093/ofid/ofac583. PMID: 36408468. Effectiveness of adjunctive rifampicin for treatment of Staphylococcus aureus bacteraemia: a systematic review and meta-analysis of randomized controlled trials. J Antimicrob Chemother. 2023 Oct 3;78(10):2419-2427. doi: 10.1093/jac/dkad214. PMID: 37583062. Adjunctive Rifampin Following Debridement and Implant Retention for Staphylococcal Prosthetic Joint Infection: Is it Effective if not Combined With a Fluoroquinolone? Open Forum Infect Dis. 2022 Oct 31;9(12):ofac582. doi: 10.1093/ofid/ofac582. PMID: 36504699.

Long Head of the Tricep Exercises, Breaking Diet Plateau, Generic GH dose and timing for Hyperplasia - Blood Sweat & Gear Coaching Podcast 287 Coaches Skip Hill, Andrew Berry, Scott McNally CHAPTERS BELOW

OCD, or Obsessive Compulsive Disorder, is a debilitating condition that involves intrusive thoughts and time-consuming, repetitive behaviors. It impacts 80 million worldwide, 2-4% of the US population or 1 in 100 people here in the US.It can be difficult to overstate the suffering caused by OCD, not only for those with this condition but also for their family members. In addition to the distress caused by the obsessional thoughts and compulsions, there can be shame and loss - loss of more meaningful, purposeful, or pleasant thoughts and behaviors. and loss of time connecting with others or engaging in purposeful or enjoyable activities.Other conditions associated with obsessive-compulsive disorder include:* Body dysmorphic disorder* Skin picking* Trichotillomania (hair pulling)* Hoarding* Hypochondria* Olfactory reference syndrome (an irrational feeling or belief that one emits a foul smell and often attempts to remove the odor).It´s not unusual for someone with OCD to have other conditions, such as:* Other forms of anxiety* Depression* ADHD* Autism spectrum disorder* Eating disorders* TourettesResearch suggests that having OCD raises one´s vulnerability to developing dementia. Many other brain conditions, however, also appear to increase this vulnerability similarly.Treatment ChallengesOCD is particularly challenging to treat. Of those with OCD, 60% do not respond to typical therapies (often medication in combination with psychotherapy involving gradual exposure to that which is being avoided). Typical medications include:* SSRI´s (Selective Serotonin Reuptake Inhibitors) -e.g., sertraline, fluoxetine, fluvoxamine, citalopram, paroxetine* Tricyclic antidepressant - clomipramine* SNRI - (Serotonin and Norepinephrine Reuptake Inhibitor) - venlafaxine* Atypical antipsychotic medications are sometimes addedMedication is combined with CBT (Cognitive Behavioral Therapy), which involves exposure and response prevention, or CBT is used alone.As you can see, most medication approaches aim to increase serotonin activity. Serotonin, however, is just one of the neurotransmitters involved. What has become increasingly clear from the research is that OCD involves abnormal activity at the NMDA receptor - a glutamate receptor.NMDA & GlutamateThe NMDA receptor is found throughout the brain. Glutamate, the primary excitatory neurotransmitter in the central nervous system, binds to the NMDA receptor. NMDA and glutamate are involved in synaptic plasticity (creating neuronal connections), learning, memory, and motor function.The synapse is the space between communicating neurons. Presynaptic neurons release glutamate, which binds to the NMDA receptor on postsynaptic neurons. This results in a cascade of signaling events that lead to “neuronal excitation.” The problem arises when this receptor has too much (or too little) activity. In the case of OCD, there is too much activity.Implications* Dysregulation at the NMDA receptor appears to play a role in OCD, depression, PTSD, schizophrenia, bipolar disorder, and substance use disorders.* Weak memory extinction can result from high activity at the NMDA receptor. While memory is a good thing, we can have problems with too much memory - or rather, problems putting our memories aside. This can look like thoughts getting stuck, for example:* Intrusive thoughts in OCD* Flashbacks in PTSD* Delusions in psychotic disorders* Cravings in addiction.* Neurodegenerative disorders, such as Alzheimer's, Parkinson's, and ALS, have also been linked to NMDA receptor malfunction.Methylation & NMDAThose who are undermethylated, especially those with OCD or addictions, have high activity at the NMDA receptor. To remind you, undermethylation is a biochemical process with many functions, including the breakdown of histamine, support of detoxification, and support of serotonin activity. When someone is undermethylated, they can tend to have allergies (from high histamine), be perfectionistic, competitive, strong-willed, have obsessive-compulsive tendencies, be ritualistic, have dietary inflexibility, and have high accomplishment or have family members with high accomplishment. Undermethylation can contribute to the low serotonin activity seen in OCD. Simply addressing undermethylation, like merely addressing serotonin, will only bring partial benefit. To address undermethylation, those of us trained by the Walsh Research Institute, use SAMe and/or methionine, B12, B6, magnesium, and antioxidants. We address this before starting methylation treatment for those with high homocysteine. But how can we also decrease activity at the NMDA receptor?Blocking NMDA & Normalizing Glutamate ActivityEsketamine or Ketamine, which has been getting much attention in recent years, can impact the brain in various ways; however, its primary mechanism is as an NMDA blocker or antagonist. For some, it can serve as a rapid-acting and highly effective antidepressant. It can also decrease OCD symptoms. Other NMDA-blocking drugs include memantine and dextromethorphan (combined with bupropion). Lamotrigine can decrease glutamate release and has been used as an adjunct medication for OCD.Nutrients, however, play an important role in the NMDA receptor. NAC or N-acetyl cysteine is a precursor to glutathione and, thus, an antioxidant. It is also anti-inflammatory and a binder for a particular toxin made by candida and mold. But, it is also a potent NMDA antagonist (decreases activity at NMDA) and has been shown to reduce obsessions and compulsions of OCD. It has also been studied in alcoholism, opiate addiction, cocaine abuse, gambling disorder, shopping disorder, cigarette addiction, and trichotillomania. It has been used by itself and as an adjunct to medication therapy. NAC has become part of the Walsh undermethylation nutrient protocols for those with OCD and/or addiction.Zinc also plays an important role in regulating functioning at the NMDA receptor. The Walsh Research Institute found that 90% of those with brain symptoms had relatively low zinc. Dosing of zinc is determined after testing plasma zinc levels using a narrow range (the Walsh/Pheiffer range differs from typical lab ranges). Zinc is checked in conjunction with copper. Zinc has been found to improve treatment response in those with OCD treated with SSRIs. Zinc can be depleted because of very high oxidative stress and/or high pyrroles, which also cause low B6. Because B6 is needed to make serotonin, pyrroles are also important to address if elevated.Inositol is a nutrient involved in the serotonin and glutamate signaling systems. It, too, is beneficial for OCD symptoms; however, it can require very high doses.The challenge of research, as you can see, is that these approaches are all looked at in isolation, as opposed to, for example, addressing undermethylation, optimizing zinc, decreasing activity at the NMDA and addressing sources of oxidative stress.Candida & MoldAside from undermethylation, low serotonin activity, and high activity at the NMDA receptor, those with OCD appear to have high oxidative stress, as is the case with most brain-related conditions. One of the more common sources of oxidative stress I see in my practice is candida overgrowth in the GI tract, which often follows antibiotic exposure and /or mold toxicity due to water damage causing seen or unseen toxic mold. Because mold and candida (yeast) thrive on sugar and a high-carb diet, symptoms can fluctuate with sugar or carb intake. How might candida and mold intersect with the NMDA receptor? Mold and yeast can contribute to high histamine states. Histamine can increase activity at the NMDA receptor. EstrogenFor women and teen girls that I see with OCD, there is often a fluctuation in their OCD symptoms with their cycle. Typically, their symptoms worsen during the times of the month when estrogen is the highest. This may be because estrogen can increase activity at the NMDA receptor.PANDAS & PANSWhen a child has an abrupt onset of OCD symptoms, PANDAS and PANS should be considered.* PANDAS = Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections* PANS = Pediatric Acute-Onset Neuropsychiatric SyndromePANDAS and PANS are autoimmune conditions, meaning the immune system is acting on the body, in this case, a part of the brain called the basal ganglia, that involves an acute onset of OCD symptoms. Other symptoms can include restricted eating, mood symptoms, regression in academic or social skills, and motor tics. While triggers are often viral, bacterial (strep in the case of PANDAS), candida,or other microbial source, what is underlying the dysregulated immune response to such microbes, in my experience, is mold toxicity. SummaryBecause OCD can be difficult to treat, my hope in sharing this information is to raise awareness that effective OCD treatments can require a multifaceted approach that includes:* addressing methylation (and high pyrroles if present) to improve serotonin activity* decreasing activity at the NMDA receptor* by optimizing zinc* using supplements or medication* addressing sources of inflammation and high histamine* address sources of oxidative stress - trauma, stress, toxins, inflammation If you find this information helpful and would like to help me get this out into the world, please consider sharing:As always, I welcome your comments, questions, and experience.Until next time,CourtneyP.S. To learn more about non-patient consultations, treatment, and monthly mentorship groups, please visit my website at:CourtneySnyderMD.comMedical Disclaimer:This newsletter and podcast episode is for educational purposes and not intended or implied to be a substitute for professional medical advice, diagnosis, or treatment for yourself or others, including but not limited to patients you are treating (if you are a practitioner). Consult your physician for any medical issues that you may be having. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit courtneysnydermd.substack.com/subscribe

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In the first edition of a special 3-part podcast series, CancerNetwork® spoke with Daniel Morgensztern, MD; Mary Ellen Flanagan, NP; and Janelle Mann, PharmD, BCOP, about best practices for implementing recently approved bispecific antibodies into cancer care. Their initial discussion focused on the clinical trial results, administration protocols, and toxicity management strategies related to the use of amivantamab-vmjw (Rybrevant) for patients with EGFR-mutated non–small cell lung cancer (NSCLC). Morgensztern is a professor of Medicine and clinical director of Thoracic Oncology in the Division of Oncology at Washington University School of Medicine in St. Louis. Flanagan is a nurse practitioner in the Division of Thoracic Oncology at Washington University in St. Louis. Mann is a clinical oncology pharmacist at Siteman Cancer Center of Washington University School of Medicine in St. Louis and manager of Clinical Pharmacy Services at Barnes-Jewish Hospital. Morgensztern began by giving an overview of amivantamab's mechanism of action and highlighting supporting data for the agent when administered alone or in combination with other agents.  The FDA initially approved amivantamab monotherapy for patients with EGFR exon 20 insertion–mutant NSCLC in May 2021 based on data from the phase 1 CHRYSALIS trial (NCT02609776). Furthermore, the agency approved amivantamab/chemotherapy as frontline treatment for patients with NSCLC harboring EGFR exon 20 insertion mutations in March 2024 based on data from the phase 3 PAPILLON trial (NCT04538664). Findings from the phase 3 MARIPOSA trial (NCT04487080) also supported the FDA approval of amivantamab plus lazertinib (Lazcluze) for those with EGFR-mutant NSCLC in August 2024. Additionally, Mann reviewed key dosing considerations as patients receive amivantamab via intravenous infusion. She detailed the use of premedication such as diphenhydramine (Benadryl) to supplement amivantamab while monitoring for toxicities during the initial infusion period, which may necessitate additional dosing adjustments. Flanagan added to the conversation surrounding infusion-related reactions by describing strategies for mitigating the risk of venous thromboembolism, cutaneous toxicities, and other adverse effects. References 1. RYBREVANTTM (amivantamab-vmjw) receives FDA approval as the first targeted treatment for patients with non-small cell lung cancer with EGFR exon 20 insertion mutations. News release. The Janssen Pharmaceutical Companies of Johnson & Johnson. May 21, 2021. Accessed January 29, 2025. https://tinyurl.com/3d8wtu4m 2. FDA approves amivantamab-vmjw for EGFR exon 20 insertion-mutated non-small cell lung cancer indications. News release. FDA. March 1, 2024. Accessed January 29, 2025. https://tinyurl.com/msw4u5yk 3. RYBREVANT® (amivantamab-vmjw) plus LAZCLUZE™ (lazertinib) approved in the U.S. as a first-line chemotherapy-free treatment for patients with EGFR-mutated advanced lung cancer. News release. Johnson & Johnson. August 20, 2024. Accessed January 29, 2025. https://tinyurl.com/yxc8u8t4

Unfortunately, today's world is filled with misinformation about hormone replacement therapies (HRTs).  And often, our primary care docs don't have the expert knowledge to explore menopause symptoms, hormone testing, and HRT options with their patients. That's why Dr. Masghati joins me today, to dive deep into tons of research-backed hormone replacement therapies to aid you in smoother perimenopause and menopause transitions.  Because we all deserve to feel our best today, and every day from here on out.  Tired of getting your symptoms brushed off by your doctor? Or done with bandaid solutions that aren't a long-term fix?  Check out this podcast for all you need to know about navigating perimenopause and menopause symptoms with the right HRT options for you!  Salome Masghati, MD, FACOG Dr. Salome Masghati is a gynecologist with specialized training in minimally invasive surgery. After dealing with multiple symptoms and hormonal imbalances, she reclaimed her health and shifted her practice to a holistic, root-cause approach to care. Inspired by her experience, she now helps women address underlying hormonal issues to achieve optimal health and improved quality of life. IN THIS EPISODE Navigating early menopause & menopause  Hormones & effective Hormone Replacement Therapies  Hormone testing & staying on top of your levels  Debunking myths around HRTs  Hormone testing in early perimenopause  Dosing hormone replacement based on your symptoms  Hormonal changes and risks for chronic diseases  QUOTES “With the hormones, get them checked no matter what age you are, then you have a baseline. When you start feeling symptomatic, it's a matter of understanding what range you're at at your baseline”  “Whatever changes are happening, there are things going on with your hormones… don't wait until hot flashes to look [into HRT].”  “When the receptors recognize it, it will have the similar function in your body, which is why we're doing it to begin with. We're not trying to just cover symptoms to cover them up.”  RESOURCES MENTIONED Dr. Masghati's Instagram Dr. Masghati's Website Book a Consultation with Dr. Masghati HERE    RELATED EPISODES  #618: Bringing Awareness to Primary Ovarian Insufficiency, Early Menopause, Hrt and Metabolic Changes With Jessica Jones 579: Hormone Replacement Options and Hormone Testing for Women In Midlife + Self Advocacy for Optimal Health with Esther Blum #572: How To Know You Are in Perimenopause Including The 40+ Symptoms Associated with Declining Hormones #558: The Science Behind Ozempic and Important Facts About Glp-1 Agonists + Hormone Replacement for Women 40+ With Dr. Tyna Moore

Two world-leading experts in photobiology join me to discuss the negative health effects indoor lighting, what we currently know about how light interacts with biological systems and what this means for your health.Watch my previous episodes with Scott and Andrew:Scott Zimmerman I - Near Infrared Light & Melatonin https://www.youtube.com/watch?v=qYqT7i8teGsScott Zimmerman II - Problem of Indoor Lighting & NIR deficiency https://www.youtube.com/watch?v=JXiOEGuIDfMAndrew LaTour I - Introduction to Photobiomodulation & Red Light Therapy https://www.youtube.com/watch?v=alntrkUDq8EAndrew LaTour II - Best Lighting for Optimal Health & Circadian Rhythms  https://www.youtube.com/watch?v=fR1GMyFETuUTIMESTAMPS00:00 Introduction to Indoor Lighting and Health05:04 Government Regulations and LED Lighting Challenges07:10 Addressing Near-Infrared Deficiency12:23 The Importance of Wavelengths and Dosing in Light Therapy16:02 Circadian Rhythms and Light Exposure21:06 Melatonin Production and Its Implications24:06 The Role of Dimming and Spectrum in Lighting28:54 The Need for Bright Light During the Day35:02 The Body as a Solar Collector40:47 The Evolution of Human Light Exposure49:17 Exploring Systemic Effects of Light Therapy52:40 The Historical Context of Light and Health54:22 Understanding the Impact of Sunlight on Health59:59 Dosing and Indoor Lighting: A Historical Perspective01:06:15 Photobiomodulation vs. Ambient Light Exposure01:17:49 Mechanisms of Light Interaction with the Body01:35:50 The Importance of Near Infrared in Photobiology01:36:35 Understanding Energy at the Molecular Level01:39:12 The Role of Light in Biological Evolution01:40:28 Photon Behavior and Biological Implications01:46:28 Criteria for Human-Friendly Lighting01:58:42 The Importance of Balanced Blue Light02:01:41 Integrating Light into the Health MovementFollow SCOTT ZIMMERMANTwitter - https://twitter.com/SZimmZooLinkedin - https://www.linkedin.com/in/scott-zimmerman-29b7b59?trk=public_post_feed-actor-nameFollow ANDREW LATOURGembaRed YouTube: https://www.youtube.com/@gembaredllc9115Website: https://gembared.com/Instagram: https://www.instagram.com/gembared/Follow DR MAXWebsite: https://drmaxgulhane.com/Private Group: https://www.skool.com/dr-maxs-circadian-resetCourses: https://drmaxgulhane.com/collections/coursesTwitter: https://twitter.com/MaxGulhaneMDInstagram: https://www.instagram.com/dr_max_gulhane/Apple Podcasts:  https://podcasts.apple.com/podcast/id1661751206Spotify:  https://open.spotify.com/show/6edRmG3IFafTYnwQiJjhwRLinktree: https://linktr.ee/maxgulhanemdDISCLAIMER: The content in this podcast is purely for informational purposes and is not a substitute for professional medical advice, diagnosis, or treatment. Never disregard professional medical advice or delay in seeking it because of something you have heard on this podcast or YouTube channel.#indoorlighting #humanhealth #nearinfrared #melatonin #circadianrhythm #LEDlighting, #photobiomodulation #lighttherapy #exclusionzone #humanfriendlylighting #circadianrhythms #circadianrhythmSend us a textPurchase tickets to Regenerate here - https://regenerateaus.com/ Support the show

In this IronOverload for IO for iTunes podcast your hosts Stevesmi and Da Mobster discuss - TB500 with Ostarine for recovery • Why recovery is so important • Combining TB500 and MK2866/Ostarine • Recovery logs discussed • Why we see more successful results in those with logs • Dosing, cycling and stacking options Link to articles: https://www.evolutionary.org/mk-2866-ostarine-sarms-exposed Link to IO threads: 1. https://www.ironoverload.io/threads/using-ostarine-gw-for-lean-gains.3409/post-64017 2. https://www.ironoverload.io/threads/sr9009-ostarine-mk2866-for-15-weeks.3391/post-63845 3. https://www.ironoverload.io/threads/going-with-a-power-stack-of-sarms.3347/post-62853 4. https://www.ironoverload.io/threads/nutrobal-and-ostarine-for-better-sleep-appetite-gains.3295/post-62100 5. https://www.ironoverload.io/threads/crossfit-and-sarms.3273/post-6150 For 1-on-1 coaching/consultation/source help start conversation by contacting Stevesmi at: https://www.elitefitness.com/forum/members/stevesmi.219851/ or https://www.evolutionary.org/forums/members/stevesmi.85/ Where to get blood tests: https://www.evolutionary.org/forums/source-talk/bloodwork-private-md-5695.html Please note we're not doctors and the opinions are ours. It's our view and is based on our experience and views on the topic. Our Podcasts are for informational purposes and entertainment only. The Freedom of speech and the 1st amendment applies

An in depth look at Dr Dean St Marts experience with SLU-PP-332. Will mitochondrial support make Bodybuilding "too easy"? Then Hair Transplants in 2025 and Dean's recent experience. Learn all about the process today on BSG Coaching Podcast with Coaches Andrew Berry and Scott McNally wit guest Dr Dean St Mart TIME STAMPS BELOW 0:00 Teaser 0:30 Welcome Dr Dean St Mart 1:30 What is SLU-PP-332 3:00 SLU-PP-332 animal research 5:20 Getting bigger AND leaner 8:40 Cognitive Benefits 10:00 Optimizing Mitochondria in Prep 12:30 Scott is getting leaner without scale drop 16:00 Negative side effects? 19:40 Dosing experience 21:20 Does our knowledge make bodybuilding “too easy”? 25:40 Training strategies to not destroy yourself on diet 31:00 MOT C - what do you get from it? 36:20 Oral vs Injectable SLU-PP-332 38:30 SLU-PP-332 half life? 42:20 SLU-PP-332 onset after dosing 43:30 GLP-1 Meds : Going hypo but NOT hungry 45:00 Hair Transplants 48:00 5 mechanisms of hair loss 50:45 How Dean Picked a clinic 51:35 2 techniques of hair transplants 53:45 Creating a hairline 56:00 what to expect in the procedure 1:02:00 Recovery from the surgery 1:10:00 Logistics of getting to the Turkish Clinic 1:19:45 The Hair Restoring Podcast with Dean Peptide Affiliates : ✅ https://parabolicpeptides.com Code THINK10 for 10% off ✅ https://aminoasylum.shop/ref/122/ Code THINK for 20% off

Of all the topics covered during interventional radiology training, dosimetry education is often delayed until after IRs enter clinical practice. In this episode, Drs. Tyler Sandow and Sabeen Dhand host a roundtable discussion with experts on the dosimetry fundamentals that all Y90 operators should understand. They are joined by interventional radiologists Drs. Zachary Berman, Kirema Garcia-Reyes, and Siddharth Padia, who provide their expert insights. Physicians, nurses, nurse practitioners, and physician assistants can follow this link to earn CME / CE credits for completing an accredited learning activity related to this discussion: https://www.cmeuniversity.com/course/take/125736 --- This podcast is supported by an educational grant from: AstraZeneca https://www.astrazeneca.com/our-therapy-areas/oncology.html With additional support from: Boston Scientific https://www.bostonscientific.com/en-US/medical-specialties/interventional-radiology/interventional-oncology.html --- SYNPOSIS The group agrees that dosimetry is not a one-size-fits-all approach. Dosing strategies depend on factors such as tumor size, perfusion territory, underlying liver function, the choice between glass versus resin spheres, and treatment intent. These considerations are illustrated with real-life case examples. The doctors also explore voxel-based dosimetry, a method for calculating the amount of radiation absorbed by different parts of the tumor. They stress the importance of learning how to perform accurate dosage calculations. Finally, the conversation touches on data from major Y90 trials, current guidelines, and the evolving perspective on Y90 as a potential curative treatment, rather than merely a bridging therapy. --- TIMESTAMPS 00:00 - Introduction 01:59 - Dosimetry Education During Training 05:46 - Benefit of Individualized Dosing 11:01 - Complications from High Doses 15:19 - Dosage Calculation Cases 22:51 - Duration of Response to Y90 25:00 - Dosing Based on Treatment Intent 29:11 - Challenging Case Example 42:31 - Voxel-Based Dosimetry 45:15 - Using Dosimetry Software --- RESOURCES LEGACY Trial (Salem et al, 2021): https://pmc.ncbi.nlm.nih.gov/articles/PMC8596669/ Voxel-based tumor dose correlates to complete pathologic necrosis after transarterial radioembolization for hepatocellular carcinoma (Pianka et al, 2024): https://pubmed.ncbi.nlm.nih.gov/38913189/ RAPY90D Trial (Kappadath et al, 2023): https://jnm.snmjournals.org/content/64/supplement_1/P268 Clinical, dosimetric, and reporting considerations for Y-90 glass microspheres in hepatocellular carcinoma: updated 2022 recommendations from an international multidisciplinary working group (Salem et al, 2023): https://pubmed.ncbi.nlm.nih.gov/36114872/ International recommendations for personalised selective internal radiation therapy of primary and metastatic liver diseases with yttrium-90 resin microspheres (Levillain, 2021): https://link.springer.com/article/10.1007/s00259-020-05163-5)

Adenosine is the first IV medication given to stable patients with sustained supraventricular tachycardia (SVT) refractory to vagal maneuvers.Symptoms indicating a stable vs unstable patient. Common causes of tachycardia. Cardiac effects of Adenosine. Indications for use in the ACLS Tachycardia algorithm. Considerations and contraindications. Adenosine as a diagnostic for patients in A-Fib or A-Flutter with RVR. Dosing and administration. Other podcasts that cover common ACLS antiarrhythmics in more detail and another covering Brugata Criteria used to differentiate V-Tach from SVT with an aberrancy, can be found on the Pod Resources page at passacls.com.Connect with me:Website: https://passacls.com@Pass-ACLS-Podcast on LinkedInGive Back & Help Others: Your support helps cover the monthly cost of software and podcast & website hosting so that others can benefit from these ACLS tips as well. Donations via Buy Me a Coffee at https://buymeacoffee.com/paultaylor are appreciated.Good luck with your ACLS class!

Send us a textBemiparin in neonatal thrombosis: therapeutic dosing and safety.Sanchez-Holgado M, Sampedro M, Zozaya C, Permuy Romero C, Alvarez-Garcia P, La Banda-Montalvo L, Nieto C, Pellicer A.J Perinatol. 2024 Dec 16. doi: 10.1038/s41372-024-02200-1. Online ahead of print.PMID: 39681735As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

In this Evolutionary.org Underground Podcast for iTunes episode your hosts Stevesmi and Da Mobster from the UK Iron Den discuss – How to utilize Testosterone in a cycle by Pharmaqo • A brief history of Testosterone • Why is testosterone so popular with users of PEDs • Choosing between TRT or performance enhancement? • Dosing, esters, cycles and more using PharmaQo products • Why we love PharmaQo Link to articles: https://www.evolutionary.org/testosterone-esters-101 Link to the Evolutionary threads discussing testosterone on cycle 1. https://www.evolutionary.org/forums/threads/1st-testosterone-enanthate-cycle-log.102013/ 2. https://www.evolutionary.org/forums/threads/im-in-love-with-testosterone-and-dbol-together.101822/ 3. https://www.evolutionary.org/forums/threads/using-testosterone-and-primo-together.102064/ 4. https://www.evolutionary.org/forums/threads/using-some-primo-and-testosterone.101802/ 5. https://www.evolutionary.org/forums/threads/low-energy-cycle-with-testosterone-only.99812/ For 1-on-1 coaching/consultation/source help start a conversation by contacting Stevesmi at: https://www.elitefitness.com/forum/members/stevesmi.219851/ or https://www.evolutionary.org/forums/members/stevesmi.85/ Where to get blood tests: https://www.evolutionary.org/forums/source-talk/bloodwork-private-md-5695.html Please note we're not doctors and the opinions are ours. It's our view and is based on our experience and views on the topic. Our Podcasts are for informational purposes and entertainment only. The Freedom of speech and 1st amendment applies.

HOPA Pharmacy Outcomes & Practice-Based Collaboration Survey: https://www.surveymonkey.com/r/MXNVRBR Dexamethasone Dosing Intensity in Multiple Myeloma: https://doi.org/10.1182/blood.2024025939 Talquetamab + Teclistamab: https://doi.org/10.1182/blood.2024025939 postMONARCH: https://doi.org/10.1200/JCO-24-02086

HAPPY NEW YEAR!!!!! First Off We at LOE would like to apologize to Nancy Reagan and her family. These alleged alligations of Nancy Reagans supposed passed should be left to the internet to discuss. NOW WITH THAT SAID. WHAT'S UP WITH ALL THE WOMEN GETTING PROMOTED FOR THEIR LOOKS AND THEN SUING FOR SEXUAL HARASSMENT? Listen up As the Crew begins 2025.......THE LOE WAY! Logikovereverything@gmail.com

Get My Book On Amazon: https://a.co/d/avbaV48Download The Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/

Felice Gersh, M.D. is a multi-award winning physician with dual board certifications in OB-GYN and Integrative Medicine. She is the founder and director of the Integrative Medical Group of Irvine, which provides comprehensive health care for women by combining the best evidence-based therapies from conventional, naturopathic, and holistic medicine. For 12 years, she taught obstetrics and gynecology as an Assistant Clinical Professor at Keck USC School of Medicine, where she was honored with the Outstanding Volunteer Clinical Faculty Award. She now serves as an Affiliate Faculty Member at the Fellowship in Integrative Medicine through the University of Arizona School of Medicine, where she lectures and regularly grades the case presentations written by the Fellowship students for their final exams. Additionally, she is a sought after medical forensic expert and has worked on numerous high profile legal cases. Dr. Felice loves writing and lecturing. She has been around the world presenting on women's health issues and she regularly publishes in peer-reviewed medical journals.    You may have already heard Dr. Felice on the podcasting circuit or in popular media like Cosmopolitan, Shape and Health magazines talking about her specialty - PCOS (Polycystic Ovarian Syndrome), menopause and other issues related to women's health.  Books: Menopause SOS https://integrativemgi.com/lp/menopause-sos/ (free) Menopause: 50 Things You Need To Know   Episode 129: ⁠Hormone Therapy for Menopause – Good or Bad?⁠ Episode 178: ⁠Mammograms – Safe or Dangerous? Episode 210: A Different Approach to Menopause Hormone Dosing. Is There Any Benefit To Cycling HRT?     Contact Dr. Felice Gersh Website: https://integrativemgi.com/ Telephone: (949) 753-7475 Facebook: @IntegrativeMGI https://www.facebook.com/IntegrativeMGI/ Facebook:  @felicegershmd  https://www.facebook.com/felicegershmd/ Twitter: https://twitter.com/DrFeliceGersh Instagram: https://www.instagram.com/dr.felicegersh/ LinkedIn: https://www.linkedin.com/in/felice-gersh-md-b0422b13/ Youtube: https://www.youtube.com/c/FeliceGershMD   Get Primeadine by Oxford Healthspan. 15% discount with code ZORA ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠. Get Mitopure by Timeline. 10% discount with code ZORA at timeline.com/zora Visit getkion.com/zora for 20% off Kion Essential Amino Acids Try OneSkin skincare for with code ZORA at https://www.oneskin.co/zora Join ⁠⁠⁠Biohacking Menopause⁠⁠⁠ before February 1, 2025 to win Kion Essential Amino Acids. 20% off at getkion.com/zora. Join the Hack My Age community on: Facebook Page : ⁠⁠⁠⁠⁠@⁠Hack My Age⁠  Facebook Group: ⁠⁠⁠⁠⁠⁠@⁠Biohacking Menopause⁠⁠⁠⁠⁠⁠ ⁠   Instagram: ⁠⁠⁠⁠⁠@⁠HackMyAge⁠  Website: ⁠⁠⁠⁠⁠⁠HackMyAge.com⁠   ⁠Biohacking Menopause⁠ Membership Group Email: zora@hackmyage.com This podcast is edited by ⁠⁠⁠⁠⁠jonathanjk@gmail.com   We cover: Rhythmic, cyclic and static dosing differences, pros and cons What are optimal levels of estradiol? The dos and don'ts of hormone dosing Bodily signs of optimal dosing How to educate yourself with rhythmic dosing A new concern about oral progesterone Dr. Gersh's personal HRT regime

Dave Crosland & Scott McNally Drugs n Stuff Podcast 252 00:00 Testosterone vs. EQ: A Comparative Analysis 10:50 Phlebotomy and Its Impact on Anabolic Dosing 14:24 First Cycle Considerations: Compounds and Dosing 22:09 Understanding TRT: Dosing and Management 25:20 The Stress of Anabolic Use: Management and Implications 27:36 The Impact of High TRT on Health 30:01 Understanding Cycle Management and Natural Testosterone 32:24 Navigating Anabolic Use and Recovery 35:43 The Role of PCT in TRT 37:58 Short vs Long Esters in Anabolic Cycles 39:25 Cruising and Cycling: Dosage Considerations 42:02 The Long Game in Bodybuilding 43:52 Goals and Aspirations for 2025 46:39 Exploring Logotherapy and Purpose 50:32 The Difference Between Happiness and Enjoyment

In this episode, we explore the RADAR trial's findings on antipsychotic dose reduction in schizophrenia. Can patients with chronic schizophrenia safely reduce or discontinue their antipsychotic medications without increasing relapse risk? The trial's results challenge common assumptions about medication reduction and provide crucial guidance for clinical practice. Faculty: Oliver Freudenreich, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.5 CME: Quick Take Vol. 62 Antipsychotic Dose Reduction in Schizophrenia: Insights From the RADAR Trial  

In this week's episode, we'll learn about the prevalence and impact of dexamethasone dose reductions during triple or quadruple therapy for newly diagnosed multiple myeloma, a conditional knockout mouse model for testing gene therapy in X-linked sideroblastic anemia, and real-world efficacy and safety of ciltacabtagene autoleucel in patients with relapsed/refractory multiple myeloma.Featured Articles:Dexamethasone dose intensity does not impact outcomes in newly diagnosed multiple myeloma: a secondary SWOG analysisAn erythroid-specific lentiviral vector improves anemia and iron metabolism in a new model of XLSASafety and efficacy of standard-of-care ciltacabtagene autoleucel for relapsed/refractory multiple myeloma

Injectable Yohimbine dosing, What does high dose T3 look like? Maltodextrin Intraworkout? Side to look out for on 1000mg Test Cycle TIME STAMPS BELOW - DNS Podcast Dave Crosland & Scott McNally

Dr Robert-Jan de Vos, sports physician and associate professor at Erasmus Medical Centre in Rotterdam, The Netherlands, dives deep into all things Achilles tendinopathy. In part 2 of this series, Dr de Vos covers the multitude of options for treatment, outside of exercise therapy. Should you and the patient consider corticosteroid injections, PRP injections, heel lifts, shockwave, NSAIDs, or surgery? And when? What are the important clinical considerations when patients choose these options? Part 2 has it all! ------------------------------ RESOURCES Terminating corticosteroid injection in tendinopathy? https://www.jospt.org/doi/10.2519/jospt.2023.11875/ Dutch multidisciplinary guideline on Achilles tendinopathy: (https://pubmed.ncbi.nlm.nih.gov/34187784/ Platelet-rich plasma injection for chronic Achilles tendinopathy: https://pubmed.ncbi.nlm.nih.gov/20068208/ Time to put down the scalpel when treating tendinopathy? https://pubmed.ncbi.nlm.nih.gov/31653777/ Why tendons like load: https://pubmed.ncbi.nlm.nih.gov/29920664/ Clinical diagnosis of Achilles tendinopathy: https://pubmed.ncbi.nlm.nih.gov/34692248/ Clinical tool for identifying spondyloarthropathy: http://tinyurl.com/3my87hma More on the pain monitoring model: https://pubmed.ncbi.nlm.nih.gov/17307888/ Dosing your resistance training in tendinopathy: https://pubmed.ncbi.nlm.nih.gov/37169370/ Best treatment for Achilles tendinopathy (living systematic review): https://pubmed.ncbi.nlm.nih.gov/32522732/ Achilles Pain, Stiffness, and Muscle Power Deficits - 2024 updated clinical practice guideline: https://www.jospt.org/doi/10.2519/jospt.2024.0302

JW and Skinny welcome in author Benjy Eisen for Episode 2 of Season 6, and the conversation was so extensive it had to be broken up into two parts! Benjy gets things started by discussing his relationship with Bill Kreutzmann, spending time with Trey Anastasio during Fare Thee Well, and the passing of Phil Lesh. Amazing stories, incredible energy, and kindness that shines through- part one with Benjy is like eating an oreo cookie. And find out where Skinny and JW go with song two of Theme From the Bottom! Thanks for listening, and Season's Greetings from all of us here at Stub Me Down Podcast! 

Dr Robert-Jan de Vos, sports physician and associate professor at Erasmus Medical Centre in Rotterdam, The Netherlands, dives deep into all things Achilles tendinopathy. As lead author of the Dutch Multidisciplinary Guideline on Achilles Tendinopathy (https://pubmed.ncbi.nlm.nih.gov/34187784/), he shares the key messages from this in-depth review. In today's episode, Dr de Vos covers the important tendon anatomy to guide your differential diagnosis, what information he is most focused on communicating to patients, and the key factors that can affect your choices when managing Achilles tendinopathy. ------------------------------ RESOURCES Why tendons like load: https://pubmed.ncbi.nlm.nih.gov/29920664/ Clinical diagnosis of Achilles tendinopathy: https://pubmed.ncbi.nlm.nih.gov/34692248/ Clinical tool for identifying spondyloarthropathy: https://www.researchgate.net/profile/Paul-Kirwan/publication/332275130_D18_SCREEND%27EM_BEFORE_YOU_TREAT%27EM_A_CLINICAL_TOOL_TO_HELP_IDENTIFY_SPONDYLOARTHROPATHY_IN_PATIENTS_WITH_TENDINOPATHY/links/5cab530da6fdcca26d06aaf1/D18-SCREENDEM-BEFORE-YOU-TREATEM-A-CLINICAL-TOOL-TO-HELP-IDENTIFY-SPONDYLOARTHROPATHY-IN-PATIENTS-WITH-TENDINOPATHY.pdf More on the pain monitoring model: https://pubmed.ncbi.nlm.nih.gov/17307888/ Dosing your resistance training in tendinopathy: https://pubmed.ncbi.nlm.nih.gov/37169370/ Best treatment for Achilles tendinopathy (living systematic review): https://pubmed.ncbi.nlm.nih.gov/32522732/ Achilles Pain, Stiffness, and Muscle Power Deficits - updated clinical practice guideline from AOPT: https://www.jospt.org/doi/10.2519/jospt.2024.0302

In this episode of the Gladden Longevity Podcast, Dr. Mike Van Thielen shares his extensive journey in health and wellness, focusing on the benefits of molecular hydrogen. He discusses his background in physical therapy, acupuncture, and holistic nutrition, leading to his interest in longevity and anti-aging. The conversation delves into the science behind molecular hydrogen, its role as a selective antioxidant, and its adaptogenic properties. Dr. Van Thielen also explains various methods of hydrogen delivery and its applications for gut health, emphasizing the importance of balance in health interventions.    For the audience:     * Use the code 'Podcast10' to get 10% OFF your order at our supplement store → https://gladdenlongevityshop.com/   * Get Mike Van Thielen's book, the Hydrogen of your choice and access to ALL the research → https://mvtonline.com/molecular-hydrogen       Takeaways    * Molecular hydrogen is gaining recognition for its therapeutic benefits.  * Hydrogen acts as a selective antioxidant, neutralizing harmful free radicals.  * It functions as an adaptogen, helping to balance bodily functions.  * Hydrogen promotes autophagy, aiding in cellular recycling.  * Hydrogen can cross the blood-brain barrier, offering neuroprotective effects.  * It is cytoprotective, benefiting mitochondrial health and energy production.  * Hydrogen is effective for gut health, improving conditions like leaky gut.  * Different delivery methods for hydrogen can be combined for optimal results.    Chapters    00:00 Introduction to Dr. Mike Van Thielen  05:51 Journey into Health and Longevity  13:46 Exploring Molecular Hydrogen  24:56 The Science Behind Hydrogen's Benefits  30:27 Hydrogen Delivery Methods and Dosing  41:08 Hydrogen for Gut Health and Conclusion  42:59 Goodbye    To learn more about Mike, get his help, his books or contact him:  Website: https://drmike.dna.clinic/  Website: https://mvtonline.com/   Instagram: https://www.instagram.com/drmike_health4life/?hl=en   Facebook: https://www.facebook.com/drmikeinspires/    Reach out to us!     Website: https://gladdenlongevity.com/      Email: podcast@gladdenlongevity.com      Facebook: https://www.facebook.com/Gladdenlongevity/     Instagram: https://www.instagram.com/gladdenlongevity/?hl=en      LinkedIn: https://www.linkedin.com/company/gladdenlongevity     YouTube: https://www.youtube.com/channel/UC5_q8nexY4K5ilgFnKm7naw 

Featuring perspectives from Dr Priyanka Sharma and Dr Sara M Tolaney, including the following topics: Introduction: Metastatic Triple-Negative Breast Cancer (mTNBC) — The Patient Perspective (0:00) Selection and Sequencing of Antibody-Drug Conjugates (5:09) Dosing and Tolerability of Sacituzumab Govitecan; Use of Anthracyclines (14:39) Case: A woman in her early 60s with relapsed TNBC (HER2 2+) who experiences disease progression on T-DXd (Grade 2 interstitial lung disease) and receives sacituzumab govitecan — Shaachi Gupta, MD, MPH (22:04) Discussing Palliative and End-of-Life Care (32:40) PARP Inhibitors for TNBC with Somatic versus Germline Mutations; Cytopenias with PARP Inhibitors (37:53) The “Art of Oncology” — Building Trust with Patients and Family Members (45:05) Case: A woman in her mid 60s with recurrent TNBC with extensive chest wall involvement — Dr Gupta (48:44) Case: A man in his mid 40s with multiregimen-refractory AR-positive TNBC with an ERBB2 exon 20 insertion mutation — Dr Gupta (52:53) CME information and select publications

Drs. Anne-Grete Märtson, Megan Wimmer, and Evan Clemens join Dr. Erin McCreary to tackle the one of the hottest debates among providers taking care of immunocompromised patients, valganciclovir dosing! Learn all about the history of valganciclovir dosing, what is valganciclovir's PK/PD target, and even valganciclovir therapeutic drug monitoring. References: Märtson AG, Edwina AE, Kim HY, Knoester M, Touw DJ, Sturkenboom MGG, Alffenaar JC. Therapeutic Drug Monitoring of Ganciclovir: Where Are We? Ther Drug Monit. 2022 Feb 1;44(1):138-147. doi: 10.1097/FTD.0000000000000925. PMID: 34610621; PMCID: PMC8746890. Wiltshire H, Paya CV, Pescovitz MD, Humar A, Dominguez E, Washburn K, Blumberg E, Alexander B, Freeman R, Heaton N, Zuideveld KP; Valganciclovir Solid Organ Transplant Study Group. Pharmacodynamics of oral ganciclovir and valganciclovir in solid organ transplant recipients. Transplantation. 2005 Jun 15;79(11):1477-83. doi: 10.1097/01.tp.0000164512.99703.ad. PMID: 15940035. This podcast is powered by Pinecast.

This episode is part two of my in-depth discussion with Dr. Praveen Arany, a world-renowned light therapy (photobiomodulation) researcher and expert who's been working in the field for over two decades. If you missed part one, I highly recommend you go back and listen to that episode. We delve into some very deep and specific science around light therapy that will prepare you for everything you hear in part two. In this episode, we get into the minutiae of light therapy dosing and also talk about a few others topics like systemic vs local effects. Similarly to part one, this is not well-suited for beginners! If you're really interested in the topic of light therapy/photobiomodulation, you'll appreciate this discussion. But if you're looking for a high-level overview, this is not for you.  If you're ready to learn more, listen in for a truly comprehensive and research-based take on light therapy dosing.   

Get ready to discover the true superfoods that can transform your health—starting with spirulina and chlorella. In this dynamic and thought-provoking episode, Dave Asprey welcomes Catharine Arnston, founder of ENERGYbits, to dive deep into the world of algae and its incredible potential to boost energy, detox the body, and support longevity. First, we challenge the myths around trendy “superfoods” and reveal why algae, particularly spirulina and chlorella, reign supreme for mitochondrial health and cellular energy. Catharine shares her 15 years of research on algae, explaining how it protects your cells, enhances brain function, and even supports cancer prevention. Next, we explore cutting-edge science on how algae supercharge mitochondrial performance, with Catharine revealing new clinical trial data that shows a 20% boost in mitochondrial function in just seven days. Finally, we break down the real-life impacts—improved brainpower, glowing skin, and detoxified cells—showing how this powerhouse algae can revolutionize the way you think about your health. This episode will change the way you approach superfoods and biohacking forever. Resources: ENERGYBits: Visit energybits.com and use code UPGRADE for 20% off your order. ENERGYbits Instagram: https://www.instagram.com/energybits/ Dave Asprey's Linktree: https://linktr.ee/daveasprey Dave Asprey's Book Smarter Not Harder: https://daveasprey.com/books Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/ Join The Human Upgrade Podcast Live – Upgrade Collective: https://www.ourupgradecollective.com Own an Upgrade Labs: https://ownanupgradelabs.com Timestamps: • 00:00 – You Won't Believe This • 00:39 – Introduction to Superfoods • 01:24 – The Benefits of Algae • 02:20 – Guest Introduction: Catharine Arnston • 03:19 – Catharine's Journey to Algae • 04:16 – The Science Behind Algae • 05:22 – Mitochondria and Algae • 05:53 – The Role of Superoxide Dismutase (SOD) • 06:24 – Alkaline Diets and Health • 22:20 – Phycocyanin: The Cancer-Fighting Pigment • 29:52 – Clinical Trials and Future Research • 31:31 – Spirulina Efficacy Study • 32:12 – Mitochondrial Health Insights • 32:56 – Intermittent Fasting vs. Spirulina • 35:27 – Testimonials and Real-Life Benefits • 39:52 – Quality Control and Safety • 43:31 – Skin Health and Algae • 47:34 – Dosing and Usage Tips • 48:18 – Brain Health and Recovery • 50:57 – Aging and Biohacking • 53:39 – Final Thoughts and Offers See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.