Podcasts about Dosing

How much is enough? How do you know when to push and when to back off? When does consistency matter more than novelty? And when do you stop? In this episode, Bart van Buchem and Tim Beames explore the clinical judgment behind dosing in persistent pain; from exercise to enrichment to life itself. Tim shares his cost-benefit framework and a walking case study that illustrates why erring on the side of caution builds more momentum than pushing too hard. Bart introduces the tides metaphor from a patient whose fluctuating symptoms needed flexible dosing, not a fixed protocol. They also discuss preparation and recovery (the Usain Bolt principle), widening the dosing lens beyond reps and sets, using embodied cues as guides, and why the last rep should never be the worst. This is the fourth instalment in a series covering agency, affordances, playfulness, and now dosing — together forming a practical framework for persistent pain rehabilitation.

How do you build a business that lasts a lifetime while making sure you do, too? Cymbiotika co-founders Shahab and Durana Elmi share the secrets behind their entrepreneurial success, from prioritizing quality over cheap production to redefining the standards for wellness products. They open up about taking risks, embracing the pain that comes with growth, and building a business rooted in passion, wellness, and the pursuit of a healthier future. Learn more about your ad choices. Visit podcastchoices.com/adchoices

Almost everything that changes the human body works best in cycles. Training. Hormones. Recovery. And potentially some of the most powerful compounds in the peptide space. In this episode of The Architect of Resilience, Anthony Castor and I sit down with Jean Francois Tremblay, founder of CanLab and a peptide researcher with more than two decades of experience, alongside Dustin Lavigne. https://chrisduffin.com/ Coaching, Peptides, Supplements, eBooks & Merch, Education, and my Free Community! A deeper dive on coaching, peptides, and regenerative amplification method at https://www.enhancedexecutive.com/

In this episode of Neph 2 America, David Lee Corbo and Matt Heppner dig into a wide-ranging mix of Biblical history, Donald Trump, Israel, predictive programming, end-times speculation, and modern health trends—all through the show's Christian worldview and conspiracy-research lens.The conversation begins with Matthew 12:21 and a debate over the word “Goyim,” before moving into reports about the possible tomb of Jesus, the Shroud of Turin, Noah's Ark, the Flood, animal kinds, and how Biblical artifacts fit into faith. From there, the episode shifts into current political and cultural controversy, including a Trump rally attendee removed after anti-Israel remarks, rising political division, antisemitism, and the growing fracture inside conservative politics and public Christianity.The hosts also react to Target's controversial Halloween costume, revisit an old Justin Bieber clip, and discuss a reported $10 million bounty involving Barron Trump, Iran, Israel, and the possibility of wider war. That leads into one of the episode's biggest threads: Donald Trump's relationship to Israel, claims about a King David bloodline, the Jewish concept of Moshiach, the Trump–King Cyrus temple coin, Israeli support for Trump, and recurring questions about whether Trump fits an Antichrist-style pattern.The discussion then goes deep into predictive programming and strange historical parallels. Topics include the 1958 Trackdown episode featuring a character named Trump who promises to build a wall, Nikola Tesla, John Trump, the Ingersoll Lockwood “Baron Trump” books, alleged time-travel connections, Trump/Israel number synchronicities, a cartoon scene featuring a demonic political figure grazed in the ear during an assassination attempt, The Simpsons, and Project Looking Glass.The final portion explores GLP-1 drugs, impulse control, violent crime, Retatrutide, peptides, appetite suppression, fitness, diet, recovery, testosterone, and the broader debate over modern health interventions.What do you think: predictive programming, coincidence, spiritual influence, or something else? Drop your take in the comments.► Subscribe for more Biblical analysis, Christian worldview discussions, and conspiracy research through a Biblical lens.Listen on Spotify, Apple Podcasts, and everywhere podcasts are available.00:00 Intro04:00 Matthew 12:21 & the Goyim Debate06:20 Tomb of Jesus, Shroud of Turin & Noah's Ark20:10 Trump Rally, Israel & Political Fracturing30:09 Target Halloween Costume Controversy39:14 Justin Bieber, Celebrity Culture & Exploitation41:36 Barron Trump Bounty, Iran & Israel45:10 Trump, King David, Moshiach & King Cyrus50:51 Trump Antichrist Pattern & Butler Shooting56:20 Trackdown's Trump, the Wall & Predictive Programming57:30 Nikola Tesla, John Trump & Time Travel59:30 Baron Trump Books & Ingersoll Lockwood61:11 Demonic Cartoon & Trump Ear-Shot Parallel63:06 Trump, Israel & 777 Number Synchronicities67:26 The Omen, Damien Thorne & Trump Parallels73:12 The Simpsons & Project Looking Glass78:18 GLP-1 Drugs, Impulse Control & Violent Crime87:44 Retatrutide Risks, Dosing & Side Effects91:31 Peptides, Recovery & Fitness99:05 Gallbladder, Testosterone & Health Talk105:33 ClosingBecome a supporter of this podcast: https://www.spreaker.com/podcast/nephilim-death-squad--6389018/support.☠️ Nephilim Death Squad — New episodes 5x/week.Join our Patreon for early access, bonus shows & the private Telegram hive.Subscribe on YouTube & Rumble, follow @NephilimDSquad on X/Instagram, grab merch at toplobsta.com. Questions/bookings: chroniclesnds@gmail.com — Stay dangerous.

Welcome to this week's Midlife Minute episode. Today, we're diving into listener questions about HRT dosing and the confusion surrounding administration. We explore several key themes, including absorption issues, lab draws, and cycling versus daily continuous dosing. I also compare oral progesterone with vaginal and transdermal progesterone. Stay tuned for more! IN THIS EPISODE, YOU WILL LEARN: The estradiol dosage range I prefer, for bone protection How heart disease risk can influence the route you select for HRT I clarify the “start low and slow” approach to HRT dosing Why women with uteruses need progesterone when taking estrogen  Why HRT dosing can become more complicated during perimenopause How FDA-approved bioidentical hormones differ from compounded preparations Various factors to consider when using an estradiol patch Alternative routes of administration for women who feel unwell when taking progesterone orally How providers can safely transition women from transdermal estradiol patches to other options Connect with Cynthia Thurlow   Follow on X, Instagram & LinkedIn Check out Cynthia's website. Submit your questions to support@cynthiathurlow.com  Join other like-minded women in a supportive, nurturing community: The Midlife Pause/Cynthia Thurlow.  Purchase Cynthia's book, The Menopause Gut. Cynthia's Intermittent Fasting Transformation Book The Midlife Pause Supplement Line Research: Please visit https://www.cynthiathurlow.com/podcast for research.

Send us Fan MailVideo Version of the Episode: https://youtu.be/JBoJCCl8W18In this episode, Adam Braus, Scot Maupin, and guest Mo Hafez explore the provocative idea of adding lithium to the water supply. They discuss potential health benefits, risks, public opinion, and the societal implications of such a bold public health measure. In this episode, Scot Maupin, Mo Hafez, and Adam Braus explore the potential of lithium in water to improve mental health, the implications of social media lawsuits, and the future of AI and societal safety measures. They discuss innovative ideas, dystopian scenarios, and the importance of democratizing technology.Keywordslithium, water supply, public health, mental health, dementia, Alzheimer's, AI psychosis, societal impact, neuroprotection, mental health treatment Lithium water, social media lawsuit, AI future, mental health, dystopian society, public safety, technology ethicsKey TopicsPotential health benefits of lithium in water, including reduction in dementia, Alzheimer's, suicidality, and violent crimeRisks and public opinion challenges of adding lithium to the water supplyThe science behind lithium's neuroprotective effects and safety at microdose levelsSocietal implications, conspiracy theories, and ethical considerations of water fluoridation and lithiumThe logistics of sourcing, distributing, and regulating lithium for public health use. Potential of lithium in water to improve mental healthLegal and societal implications of social media lawsuitsFuture scenarios of AI development and regulationDystopian vs utopian visions of technologyThe importance of democratizing AI and technologyGuest Name:Mo Hafez:Mo's Socials:YouTube - BeyondtheBytePodcastInstagram - beyond.the.byteX - bytewisepodcastLinkedIn - bytewise-aiSound Bites"Small amounts of lithium can protect against dementia.""Lithium in water could lower suicide rates by 58 percent.""Lithium in water reduces depression, suicidality, and violent crime."Chapters(00:00)Introduction to the Lithium Water Idea(03:01)Historical Context of Art and Madness(03:59)Scientific Evidence Linking Lithium to Reduced Dementia and Crime(06:00)Public Opinion and Ethical Concerns of Water Additives(06:59)The Role of Technology in Van Gogh's Life(08:03)AI Psychosis and the Role of Lithium in Society(09:56)Risks, Dosing, and Safety of Lithium in Water(11:53)Feasibility, Sourcing, and Public Acceptance(12:11)Social Media Lawsuit and Its Implications(14:05)Potential Societal and Conspiracy Theories(15:59)Practical Steps and Future Research(17:02)Potential Benefits of Lithium Water for Public Health(18:05)Cultural and Historical Perspectives on Water Additives(20:00)Conclusion: Balancing Benefits and Risks(21:59)Dystopian Scenarios: Equilibrium and Control(27:00)Future Regulations on Social Media Usage(31:59)The Ethics of Water Additives and Public Safety(37:00)The Future of AI: Risks and Opportunities(41:59)Power Dynamics in AI Development(47:03)Innovative Ideas and Closing RemarksSupport the showHelp these new solutions spread by ...Subscribing wherever you listen to podcastsLeaving a 5-star review Sharing your favorite solution with your friends and network (this makes a BIG difference)Comments? Feedback? Questions? Solutions? Message us! We will do a mailbag episode.Email: solutionsfromthemultiverse@gmail.comAdam: @ajbraus - braus@hey.comScot: @scotmaupinadambraus.com (Link to Adam's projects and books)The Perfect Show (Scot's solo podcast)Thanks to Jonah Burns for the SFM music.

The 3 "Longevity Drugs" That Fail the Data, and 4 Repurposed Ones Worth Considering Back with another solo episode, this one on Big Pharma! Metformin, rapamycin, and statins are three of the most trusted names in longevity, and none of them hold up the way you've been told. This episode breaks down the human data behind the drugs everyone assumes are safe, and reveals four lesser-known repurposed pharmaceuticals that might do more for your metabolism, mitochondria, and lifespan. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Dave walks through why metformin blunts the muscle-building signal your body needs from exercise, why rapamycin's stunning mouse studies fell apart in the 2025 PEARL trial, and why statins help one person in a hundred while draining the CoQ10 your mitochondria depend on. Then he lays out the yes list: tadalafil for vascular and brain health, SGLT2 inhibitors for metabolic and kidney protection, acarbose for gut and longevity markers, and low dose naltrexone for calming an overactive immune system. Host Dave Asprey is the father of biohacking, founder of Danger Coffee and Smarter Not Harder, and a New York Times bestselling author who has spent decades studying human performance, functional medicine, and the science of not aging. As co-founder of Unlimited.Life, a concierge longevity practice that runs over $50,000 in lab work per client, he pulls back the curtain on what the data actually shows once you strip away the marketing. This is essential listening for anyone serious about biohacking, longevity, anti-aging, human performance, brain optimization, and hacking their own biology with real supplements and functional medicine tools instead of guesswork. You'll Learn: Why metformin can cancel out the muscle gains from resistance training and drain your B12 for years What the 2025 PEARL trial actually found when rapamycin was tested in healthy adults Why statins carry a 100-to-1 harm-to-benefit ratio and quietly starve your mitochondria of CoQ10 How tadalafil supports nitric oxide, vascular health, and neuroplasticity at low daily doses Why SGLT2 inhibitors trigger ketosis-like metabolic effects and protect kidney function How acarbose changes gut bacteria and shows some of the strongest longevity data in mouse studies How low dose naltrexone modulates the immune system and reduces neuroinflammation How to talk to your doctor about using these drugs off-label for longevity instead of disease treatment Thank you to our sponsors! - ALP | Go to alppouch.com, code DAVE for 10% off. - Timeline | Visit timeline.com/dave and get up to 20% off when you subscribe and save. - Kinetic | Instead of pushing your system harder, Kenetik feeds your brain the ketones it craves to fuel calm clarity and steady focus. Go to drinkkenetik.com/DAVE and use code DAVE for a discount. - Visit www.myvitalc.com/davesfav to unlock Dave's discount Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights inhealth, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: Metformin, Rapamycin, Statins, Tadalafil, Cialis, SGLT2 inhibitors, Jardiance, Acarbose, low dose naltrexone, longevity drugs, anti-aging medication, repurposed pharmaceuticals, off-label drugs, mTOR inhibitor, AMPK, autophagy, endothelial dysfunction, CoQ10, insulin resistance, mitochondrial efficiency, senescent cells, nitric oxide, neuroinflammation, vascular health, PEARL trial, Unlimited.Life Resources: • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15? • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 00:00 – Trailer 01:01 – Intro 03:48 – Metformin 09:18 – Rapamycin 12:55 – Statins 17:28 – Statins & CoQ10 19:38 – Tadalafil 23:43 – SGLT2 Inhibitors 26:12 – Acarbose 28:40 – Low-Dose Naltrexone (LDN) 31:44 – Dosing & Recap See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

What questions do you have about GLP-1 medications and weight loss? In this episode of Back on Track: Achieving Healthy Weight Loss, I'm doing something a little different. I'm answering five real questions that viewers have left on my YouTube videos and social media about weight loss medications. I'll talk about whether you can take Contrave with a GLP-1, whether GLP-1 medications are an option if you have hypothyroidism or Hashimoto's disease, and whether it's safe to increase your dose faster if you aren't experiencing side effects. I'll also explain what to do if you need to change your injection day or miss a dose, and how to think about calorie intake when you're trying to lose weight. These are questions I hear frequently, and I want to give you a better understanding of the issues to discuss with your own healthcare provider. This podcast is for education only, and because I don't know your individual medical history, it's important to talk with your own doctor about what's right for you. Episode Highlights: Can Contrave can be taken with a GLP-1 How Contrave may help with hunger, cravings, and food noise GLP-1 medications and hypothyroidism or Hashimoto's disease Which thyroid conditions are contraindications for GLP-1 medications Why I recommend starting at a low dose and increasing slowly How I decide when it may be time for a patient to increase their dose What to do if you need to change your GLP-1 injection day What happens if you miss a GLP-1 dose Why eating too little can work against your weight-loss efforts How the NIH Body Weight Planner can help you determine your calorie needs Why fueling your body with balanced meals is important during weight loss And this is just Part 1. In Part 2 of Ask the Obesity Doctor, I'll answer more questions about GLP-1 safety, compounded and counterfeit medications, black-market peptides, medication interactions, side effects, and "Ozempic face." If you're using a GLP-1 medication, considering one, or simply have questions about weight loss medications, I hope these answers help you have a more informed conversation with your healthcare provider. Connect with Dr. Alicia Shelly Website | drshellymd.com Facebook | www.facebook.com/drshellymd Instagram | @drshellymd Linked In | www.linkedin.com/in/drshellymd Twitter | @drshellymd About Dr. Alicia Shelly Dr. Alicia Shelly was raised in Atlanta, GA. She received her Doctorate of Medicine from Case Western Reserve University School of Medicine in Cleveland, OH.  Dr. Shelly has been practicing Primary Care and Obesity medicine since 2014.  In 2017, she became a Diplomat of the American Board of Obesity Medicine. She is the lead physician at the Wellstar Medical Center Douglasville. She started a weekly podcast & Youtube channel entitled Back on Track: Achieving Healthy Weight loss,  where she discusses how to get on track and stay on track with your weight loss journey. She has spoken for numerous local and national organizations, including the Obesity Medicine Association, and the Georgia Chapter of the American Society of Metabolic and Bariatric Surgeons. She has been featured on CNN, Fox 5 News, Bruce St. James Radio show, Upscale magazine, and Shape.com. She was named an honoree of the 2021 Atlanta Business Chronicle's 40 under 40 award. She also is a collaborating author for the, "Made for More: Physician Entrepreneurs who Live Life and Practice Medicine on their own terms''. Resources: FREE! Discover the 5 Reasons Your Weight-Loss Journey Has Gotten Derailed (And How To Get Back On Track!)

Kristen Greene, Nicholas Piccicacco, and Mel O’Neal, ID Clinical Pharmacists at Tampa General Hospital, present an overview of antimicrobial dosing strategies to optimize efficacy and effectiveness of these therapies. Topics covered include pharmacokinetics, pharmacodynamics, vancomycin dosing, the importance of drug binding, dosing in renal insufficiency, and Beta-lactam allergies.

What if the key to a more effective detox isn't taking less—but taking the right amount? In this episode of the Health Fix Podcast, Dr. Jannine Krause sits down with Jeff Hoyt, founder of Zeolite Labs, to take a deep dive into zeolite, detoxification, binders, and why the way you dose a binder may dramatically affect how you feel. Jeff explains how natural clinoptilolite zeolite works as a selective "smart binder," the differences between powdered, liquid, nano, and synthetic zeolite, and why quality and particle size matter. He also shares his controversial "dosing paradox"—the idea that, for some people, microdosing zeolite may actually trigger more detox reactions than a higher dose. They also explore detox reactions, nervous system sensitivity, gut health, EMFs, heavy metals, testing, and how supporting the body's overall health may be more important than aggressively targeting a single toxin. In This Episode, You'll Learn: What zeolite is and how it supports detoxification The "swap and drop" mechanism and why zeolite is considered a selective binder Natural vs. liquid, nano, and synthetic zeolite Why purity, particle size, and quality matter The surprising "dosing paradox" and why more may sometimes be better than microdosing Detox reactions, nervous system sensitivity, and how to minimize them Zeolite's potential role in gut health, heavy metals, and EMF sensitivity How to approach testing and support your body's natural detox pathways Key Takeaway Detoxification isn't necessarily about pushing harder or tolerating more symptoms. As Jeff explains, the goal is to support the body's ability to move unwanted compounds out without overwhelming the system in the process. If you're curious about zeolite or have struggled with detox reactions in the past, this conversation offers a deeper look at how binders work—and why the dose, quality, and form of the product matter. Note: This episode discusses information and experiences shared by the guest and is intended for educational purposes. Detox protocols and supplements should be considered in the context of your individual health needs and, when appropriate, with guidance from a qualified healthcare professional. Connect with Jeff Hoyt Jeff Hoyt is a wellness educator and the founder and President of Zeolite Labs LLC . Transitioning from a background running alternative wellness clinics, he now focuses on mineral-based detoxification and is the creator of the dietary supplement ZeoCharge™. As host of The Detox Experience Podcast, Hoyt is best known for pioneering his "Higher Dose Theory," which advocates for unconventional zeolite dosing protocols to help people target heavy metals, mold, and environmental toxicants. https://www.thezeolitecoach.com/ Instagram: @ZeoliteLabs Connect with Dr. Jannine Krause Check out Dr. Krause's Website for more resources and subscribe for more conversations on functional medicine, longevity, brain health, hormones, nutrition, and natural strategies to optimize your health. Be sure to Like, Subscribe, and Share this episode with someone who wants to protect their brain and age with vitality.    

The article referenced in this episode, “Clinical Approaches to Managing Glycemia with the iLet Dosing Decision Software,” can be found here. Listen to more episodes of Diabetes Care Conversations at https://www.adces.org/practice/the-huddle-podcastLearn more about ADCES and the many benefits of membership at adces.org/join.The Diabetes Care Conversations Podcast is edited by JAG Podcast Productions: https://jagpodcastproductions.com/ Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

If you already ran BPC-157 and TB-500 and still have a nagging injury, this one is for you.MGF stands for mechano growth factor. It is a 24 amino acid fragment of IGF-1. That is the growth factor your body makes in response to training and damage. It came out of the bodybuilding world as a site injection peptide. That never panned out.What it actually does is more interesting to me. It does not raise your IGF-1 levels. It seems to make your tissue more sensitive to the IGF-1 you already have. More bang for your buck out of what is already there.I want to be straight about the evidence. Novartis and GlaxoSmithKline both tried to reproduce the original findings and failed. Human data is thin. Most of what we have is animal work on bone healing, cardiac recovery, and tissue quality.I cover what MGF is and how PEG-MGF differs. Dosing tiers, cycling, injection technique, and troubleshooting. Plus how to stack it with BPC-157, TB-500, GHK, and growth hormone peptides.Think of this one as a supporting actor. It makes everything else you are doing work better. It is not going to grow your glutes on its own.⚠️ For research and entertainment purposes only. ⚠️

Apply to work with the MI team → https://muscleintelligence.com/apply Ryan Smith co-founded the first pharmacy in the United States to offer an extensive list of peptides — and he ran the synthesis floor himself. Preparative HPLC, mass spec, chemical synthesis, the lot. Which means he spent years watching the same two failures from the inside: the molecule that works beautifully at a small dose and stops working when someone doubles it, and the vial that looks identical to the real thing and isn't. He is not a peptide evangelist. Ask him about the compound he calls ten million times more potent than BDNF and he'll tell you why he doesn't take it. His argument here is quieter than most of what gets said about peptides, and harder to unhear afterward: the body is already a competent system, and nearly everything that goes wrong with these compounds comes from handing it more input than it needed. Why exogenous growth hormone removes a brake the secretagogues leave in place. Why ipamorelin became the standard despite releasing less growth hormone than the compounds it replaced. Why two vials of the same peptide, at the same purity, can behave completely differently. He would rather talk about what he refuses to make than what he's excited about — and by the end of the hour it's clear those are the same conversation. 5 Key Takeaways Why exogenous growth hormone removes a brake your body doesn't get back — and what CJC-1295, ipamorelin and tesamorelin do instead The reason ipamorelin became the clinical standard despite releasing less growth hormone than the compounds it replaced Why the same 500-microgram dose of oral BPC-157 works in one form and barely at all in another Why the peptide he calls 10 million times more potent than BDNF is the one he leaves out of his own stack What a clean HPLC mass spec report still can't tell you about what's in the vial — and why that one blind spot lands on your liver Chapters 0:00 Why Peptides Took a Century to Arrive 4:54 Specificity, Growth Hormone & the Scalpel Argument 16:22 Thymosin Alpha-1, Epitalon & Natural Testosterone 25:25 Mitochondrial Peptides & the Fat Loss Compounds 32:27 BPC-157: Repair, Dosing & the Salt Form Problem 35:46 Peptides for the Brain: FGL, Dihexa & Cerebrolysin 47:05 What He Takes, What He Refuses & Why 52:36 Side Effects, Purity & What's Really in the Vial Connect with Ryan X – https://x.com/ryansmithepiage LinkedIn – https://www.linkedin.com/in/ryan-smith-lexington-ky/ TruDiagnostic – https://www.trudiagnostic.com

A Podcast from Obstetrics & Gynecology highlighting the latest research and practice updates in the field. This episode features interviews with Dr. Ethan A. Litman, author of the article, "A Quality-Improvement Study Evaluating Three Postpartum Prophylactic Oxytocin Rates and Blood Loss After Vaginal Birth," and Dr. Moeun Son, author of the related editorial, "Moving Toward Standardization of Prophylactic Oxytocin Dosing in the Third Stage of Labor." This episode is sponsored by ModMed. Eliminate after-hours charting and get your life back with the AI-Powered Practice and software built exclusively by OBGYNs, for OBGYNs. For more information, visit modmed.com/obgynfirst This session and the information presented is designed as an educational resource to aid clinicians when providing obstetric and gynecologic care and for information purposes only. The use of this information is voluntary, and clinicians should be familiar with and comply with all applicable laws and regulations. This information is not intended to be used as a substitute for your independent judgment, is not medical advice and should not be considered as inclusive of all proper treatments or methods of care or as a statement of the standard of care. The information provided reflects the views of the presenters and not necessarily the views of ACOG, and is provided "as is" without any warranty of accuracy, reliability or otherwise, either express or implied. Neither ACOG Foundation, the American College of Obstetricians and Gynecologists, nor its officers, directors, members, employees, and agents, will not be liable for any loss, damage, or claim with respect to any liabilities, including direct, special, indirect, or consequential damages, incurred in connection with this session or the information presented. ACOG does not guarantee, warrant, or endorse the products or services of any firm, organization, or person.

After a five-year hiatus, Dan Go returns to break down a sustainable approach to fat loss for busy people who do not have hours to spend in the gym. He explains why identifying the main physiological or psychological bottleneck—such as late-night eating, stress, grazing, or weekend overeating—can matter more than simply handing someone a meal plan. The conversation covers calorie tracking for awareness, protein and fiber for satiety, meal timing, restaurant strategies, preserving muscle with low-volume strength training, FFMI as an alternative to BMI, and a balanced view of GLP-1 medications that considers both their benefits and trade-offs. Dan Go is a fitness coach and entrepreneur whose work focuses on helping busy professionals, founders, and entrepreneurs improve their body composition, health, and performance through sustainable nutrition, behavior change, and efficient training. His coaching approach emphasizes identifying the specific habits, beliefs, and environmental factors that make fat loss difficult, then building practical systems and guardrails that clients can maintain long term. Rather than relying on extreme diets or high-volume workouts, he focuses on awareness, consistency, adequate protein, structured eating, and time-efficient strength training to help clients lose fat while preserving muscle. [Dan Go Official Website] — Dan Go (Dan Go) https://www.dango.co/ [The High Performance Journal] — Dan Go (Dan Go) https://www.dango.co/newsletter [Dan Go on X] — Dan Go (X (formerly Twitter)) https://x.com/CoachDanGo [Dan Go on Instagram] — Dan Go (Instagram) https://www.instagram.com/coachdango/ [Dan Go Private Coaching] — High Performance Founder / Dan Go (High Performance Founder) https://highperformancefounder.com/private-coaching [Why I Quit Drinking Alcohol] — Mark Manson (Mark Manson) https://markmanson.net/why-i-quit-drinking-alcohol [A Satiety Index of Common Foods] — S. H. Holt, J. C. Miller, P. Petocz & E. Farmakalidis (PubMed) https://pubmed.ncbi.nlm.nih.gov/7498104/ [Fat-Free Mass Index (FFMI) Research] — Loenneke et al. (PubMed Central (PMC)) https://pmc.ncbi.nlm.nih.gov/articles/PMC3445648/ [ChatGPT] — OpenAI (ChatGPT) https://chatgpt.com/ [Claude] — Anthropic (Claude) https://claude.com/ [Mounjaro (tirzepatide)] — Eli Lilly and Company (Mounjaro) https://mounjaro.lilly.com/ [Ozempic (semaglutide)] — Novo Nordisk (Ozempic) https://www.ozempic.com/   Show Notes   00:00 Welcome to the Hart2Heart Podcast 00:49 Rapid Fat Loss Setup 01:11 Find The Bottleneck 02:38 Late Night Eating Roots 04:21 Mark Manson Case Study 05:55 Metabolic Reset Phase 06:38 After Weight Loss Plan 09:29 Remove Obstacles First 10:59 Sustainable Diet Rules 13:03 No Cheat Meals 13:15 90 10 Ratio Diet 15:27 Tracking For Awareness 18:12 Calorie Blind Spots 19:45 Guardrails Not Counting 21:43 Satiety And Fiber 24:24 GLOP Protein Breakfast 28:36 Why Eat Breakfast 30:14 Breakfast Beats Stress 31:22 Night Eating Guardrails 32:53 Sleep and Late Meals 34:15 Restaurant Ordering Hacks 38:49 Keep Muscle While Cutting 45:30 FFMI Over BMI 47:31 GLP-1s Balanced Take 54:25 Dosing and Nutrition Guardrails 57:50 Men vs Women Fat Loss 59:58 Where to Find Dan Go   The Hart2Heart podcast is hosted by family physician Dr. Michael Hart, who is dedicated to cutting through the noise and uncovering the most effective strategies for optimizing health, longevity, and peak performance. This podcast dives deep into evidence-based approaches to hormone balance, peptides, sleep optimization, nutrition, psychedelics, supplements, exercise protocols, leveraging sunlight, and de-prescribing pharmaceuticals — using medications only when absolutely necessary. Beyond health science, we explore the intersection of public health and politics, exposing how policy decisions shape our health landscape and what actionable steps people can take to reclaim control over their well-being. Guests range from out-of-the-box thinking physicians such as Dr. Casey Means (author of "Good Energy") and Dr. Roger Sehult (Medcram lectures) to public health experts such as Dr. Jay Bhattacharya (Director of the National Institutes of Health (NIH) and Dr. Marty Mckary  (Commissioner of the Food and Drug Administration (FDA) and high-profile names such as  Zuby and Mark Sisson (Primal Blueprint and Primal Kitchen). If you're ready to take control of your health and performance, this podcast is for you.We cut through the jargon and deliver practical, no-BS advice that you can implement in your daily life, empowering you to make positive changes for your well-being.   Connect with Dr. Mike Hart Instagram: @drmikehart Twitter: @drmikehart Facebook: @drmikehart

In this episode, Dr. Rena Malik is joined by Dr. Rachel Rubin to unpack the complexities of menopause management, hormone therapy, and sexual health. They discuss the major gaps in medical training around menopause, the challenges patients face in getting evidence-based care, and the importance of individualized treatment. Listeners will gain vital insights into hormonal changes, how to advocate for better care, and why sexual health should be considered a key aspect of overall wellness. Become a Member to Receive Exclusive Content: ⁠renamalik.supercast.com⁠ Schedule an appointment with me: https://www.renamalikmd.com/appointments ▶️Chapters: 00:00 Why Menopause Care Falls Through the Cracks 03:40 The Need for Better Hormone Prescribing 04:24 Menopause, Testosterone, and Quality of Life 07:37 What Happens When Estrogen Drops 10:26 Finding the Right Hormone Toolbox 13:40 Dosing, Absorption, and Hormone Levels 22:05 IUDs, Perimenopause, and Treatment Decisions 23:28 Brain, Heart, and Whole-Body Health 30:41 Changing the Conversation Around Sexual Medicine Let's Connect!: WEBSITE: ⁠http://www.renamalikmd.com⁠ YOUTUBE: ⁠https://www.youtube.com/@RenaMalikMD⁠ INSTAGRAM: ⁠http://www.instagram.com/RenaMalikMD⁠ TWITTER: ⁠http://twitter.com/RenaMalikMD⁠ FACEBOOK: ⁠https://www.facebook.com/RenaMalikMD/⁠ LINKEDIN: ⁠https://www.linkedin.com/in/renadmalik⁠ PINTEREST: ⁠https://www.pinterest.com/renamalikmd/⁠ TIKTOK: ⁠https://www.tiktok.com/RenaMalikMD⁠ ------------------------------------------------------ DISCLAIMER: This podcast is purely educational and does not constitute medical advice. The content of this podcast is my personal opinion, and not that of my employer(s). Use of this information is at your own risk. Rena Malik, M.D. will not assume any liability for any direct or indirect losses or damages that may result from the use of information contained in this podcast including but not limited to economic loss, injury, illness or death. Learn more about your ad choices. Visit megaphone.fm/adchoices

Cameron is joined by Dr. Sean Arora, doctor, and they discuss the evolving landscape of obesity treatment, particularly focusing on GLP-1 medications and peptides. They explore the significant changes in medical approaches to obesity, the role of telehealth, and the importance of compliance and safety in the use of these medications. The conversation also delves into the complexities of compounding pharmacies and the current regulatory environment surrounding these treatments, emphasizing the need for diligence and caution in sourcing medications. In this conversation,Cameron and Dr. Arora talk about the evolving landscape of healthcare, particularly focusing on the use of peptides and GLP-1 medications. They explore the need for more clinical trials, the importance of compliance in marketing, and the misconceptions patients have about these medications. They also highlight the challenges of navigating pharmacy classifications and the necessity of a robust infrastructure for clinics to ensure long-term success in a rapidly changing regulatory environment.Listen In!Thank you for listening to this episode of Medical Millionaire!Takeaways:The healthcare infrastructure is struggling to keep up with rapid advancements in obesity treatment.GLP-1 medications represent a significant shift in how obesity is treated, moving beyond traditional methods.Pharmacological tools are now capable of producing meaningful weight loss at scale.The evolution of GLP-1 medications is just the beginning of a broader transformation in modern medicine.Patient safety and compliance are critical in the use of GLP-1 medications and peptides.Compounding pharmacies must adhere to strict regulations to ensure patient safety.The demand for effective obesity treatments is driving innovation in the pharmaceutical industry.Healthcare providers must vet their pharmacy partners to ensure compliance and safety.The regulatory landscape for peptides is evolving, with positive news on the horizon.Awareness and education are essential for both providers and patients in navigating the peptide market. There's a lot of human use cases and anecdotal data.The right type of oversight is crucial for progress.Compliance is essential when launching new wellness programs.Marketing regulations can hinder the promotion of peptides.Patients often misunderstand how GLP-1 medications work.Dosing errors can lead to serious health issues.Understanding pharmacy classifications is vital for clinics.Long-term strategies should focus on compliance and education.Collaboration among industry players is necessary for change.The regulatory landscape is complex and constantly evolving.Medical Millionaire: The Blueprint for Scaling a World-Class Medical Aesthetics PracticeWelcome to Medical Millionaire, the go-to podcast for forward-thinking Medspa owners, Medical Aesthetics leaders, Plastic Surgery & Dermatology practices, Concierge Wellness clinics, and Elective Healthcare entrepreneurs who are ready to scale with intention and operate like a true, high-performing business.If you're building, growing, optimizing, or preparing to exit your aesthetics or wellness practice, this show is your competitive advantage.Hosted by Cameron Hemphill Your Guide to Sustainable, Scalable Growth Your host, Cameron Hemphill, is one of the most trusted growth strategists in Medical Aesthetics and Elective Wellness.With over 10 years in the industry, Cameron has helped scale 1,000+ practices and more than 2,300 providers, working alongside the most recognized KOLs, national brands, EMRs, tech companies, and private equity groups, shaping the future of aesthetics. From marketing to operations, from finance to leadership, Cameron brings a real-world, data-driven perspective on what it takes to turn a practice into a powerful business engine.What This Podcast Is All About: Each episode takes you behind the scenes of the fastest-growing practices in the country, revealing the systems, strategies, and mindset required to win in today's Medical Aesthetics landscape.Expect tactical insights, step-by-step frameworks, and conversations with:Industry thought leadersTop injectors & medical directorsEMR & tech innovatorsOperations expertsMarketing strategistsPrivate equity & M&A advisorsWellness and longevity pioneersThis is where aesthetics, business, technology, and wellness converge. What You'll Learn on Medical Millionaire Every week, you'll access expert guidance to help you scale profitably and predictably, including:Marketing & Brand PositioningCRM + Lead Management SystemsPatient Acquisition & ConversionEMR Optimization & Tech Stack ArchitectureSales Psychology & Consultation MasteryFinance, KPIs, and Practice EconomicsOperational Workflows & AutomationIndustry Trends Backed by Real Benchmark DataPatient Retention & Lifetime Value ExpansionMindset, Leadership & Team DevelopmentWhether you're opening your first location or running a multi-million-dollar enterprise, you'll gain the clarity and direction to grow with confidence. A Show Designed for Every Stage of Practice Growth Medical Millionaire breaks down the journey into four essential stages, showing you exactly how to move from one to the next:Startup – Build the foundation and attract your first wave of patientsGrowth – Scale revenue, expand services, and strengthen operationsOptimize – Increase efficiency, margins, and customer experienceExit – Prepare your practice for maximum valuation and acquisitionIf You're Ready to Grow, This Is Where You Start. Tune in weekly for actionable insights, expert interviews, and the exact playbooks high-performing practices use to dominate their markets. This is the podcast for Medspa owners who want more than a job; they want a scalable, profitable, industry-leading business. Welcome to Medical Millionaire.Let's build your practice into the empire it deserves to be.

Send us Fan MailJoin the conversation as Dr. Tori Hudson and host Dr. Jaclyn Smeaton discuss the evolution of menopause hormone therapy through the eras: pre-2002, post-Women's Health Initiative, and the current state of menopause hormone therapy, with a particular focus on testosterone therapy. This episode also covers: Testosterone usage and dosing and the correlation with libido, mood, energy, and muscle mass Dr. Hudson's dosing protocols and concerns about supraphysiological dosing Methods of delivery for estrogen therapy Cardiovascular disease as an underappreciated priority in menopause care The importance of individualized care over following hormone therapy trends Show Notes Check out The American Heart Association's PREVENTä Online Calculator mentioned in this episode.Read Dr. Hudson's DUTCH Article on testosterone prescribing in postmenopausal women, and check out the testosterone guidelines discussed in this episode. Learn more about Dr. Tori Hudson and her practice, A Woman's Time! Explore easy at-home collection for patients with DUTCH Direct. Become a DUTCH Provider to get access to peer-reviewed and validated research, comprehensive patient reports, and expert clinical support. 

Could the way Ozempic is being dosed be putting people in the emergency room? Ozempic and other GLP-1 medications have transformed weight loss and blood sugar management—but dosing mistakes, incorrect measurements, rapid dose increases, and improper use can lead to serious complications.In this episode of Accelerated Health with Sara Banta, I break down Ozempic dosing mistakes that may send people to the ER, what can go wrong, warning signs you should never ignore, and why following proper dosing instructions matters.If you're using Ozempic, Wegovy, or another GLP-1 medication—or considering one—this information could help you recognize potential risks before they become an emergency.Listen until the end and share this video with someone using a GLP-1 medication.Supplements Featured In This Episode:• Acceleradine® Iodine https://www.acceleratedhealthproducts.com/products/acceleradine-iodine-supplement • Accelerated Thyroid® https://www.acceleratedhealthproducts.com/products/accelerated-thyroid-supplement • Accelerated Liver Care® https://www.acceleratedhealthproducts.com/products/accelerated-liver-care • Accelerated AMINOS® https://www.acceleratedhealthproducts.com/products/accelerated-aminos Not sure what food to eat and avoid? This guide is for you.⬇️

Piracetam, Racetams & Nootropics: Dave Asprey on the Original Smart Drug, Brain Optimization and How to Biohack Memory, Focus and Cognitive Decline We're excited to bring you another Dave solo education masterclass, this one breaking down the molecule that started the entire nootropics industry: Racetams Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey pulls back the curtain on piracetam and the racetam family, the original nootropics that quietly built the foundation for modern human performance and brain optimization. As the father of biohacking and someone who has taken racetams almost every single day for 25 years, Dave brings firsthand experience most experts simply don't have. He built two Bulletproof-era companies and led the biohacking movement while running this stack daily, and in this episode, he shares exactly how it worked for him. Dave traces the strange 1964 Belgian lab discovery that forced scientists to invent the word "nootropic" in the first place, then breaks down how these compounds shift acetylcholine, glutamate, and AMPA signaling to improve memory, focus, and neuroplasticity without touching dopamine or spiking your heart rate. He covers the mitochondria and membrane fluidity mechanisms behind the anti-aging and longevity effects, walks through dosing for all five major racetams, and explains who actually benefits versus who's wasting their money. This is essential listening for anyone serious about biohacking, human performance, functional medicine, and brain optimization. Whether you're stacking supplements for sleep optimization, exploring fasting and ketosis for metabolism, or just trying to think clearer without sacrificing your health, this episode hands you a real framework for hacking cognitive decline before it starts. You'll Learn: Why piracetam forced scientists to invent the term "nootropic" and what actually qualifies as one How racetams change acetylcholine, glutamate, and AMPA signaling without acting like a stimulant The link between racetams, mitochondria, and neuroplasticity, and why it matters for anti-aging Dosing breakdowns for piracetam, aniracetam, oxiracetam, pramiracetam, and phenylpiracetam Who benefits most: aging brains, stroke recovery, athletes, and anyone flying frequently How to stack racetams with choline, Danger Coffee, and other supplements the smarter not harder way The regulatory mess keeping safe, tested nootropics out of reach in the US Thank you to our sponsors! - ALP | Head to http://alppouch.com/ and use code DAVE for 20% off your first order. - Pique | Head over to Piquelife.com/Dave to get 20% off your order. - OneSkin | Get 15% off OneSkin with the code DAVE at https://www.oneskin.co/DAVE #oneskinpod Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights inhealth, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: piracetam, racetam, nootropics, smart drugs, aniracetam, oxiracetam, pramiracetam, phenylpiracetam, cognitive enhancement, brain optimization, memory improvement, neuroplasticity, mitochondrial function, acetylcholine, glutamate AMPA receptors, choline supplements, CDP-choline citicoline, alpha-GPC, brain fog remedy, stroke recovery cognitive, dementia prevention, biohacking supplements, Dave Asprey nootropics, longevity brain health, focus and concentration, memory recall, cognitive decline aging Resources: • Download Dave's Free Peptide Guide at daveasprey.com/peptide-guide. • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15? • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 00:00 – Trailer 01:10 – Intro 04:30 – Birth of the Nootropic 08:55 – How Racetams Work 12:51 – Membranes & Blood Flow 15:55 – Piracetam: The Original 19:30 – Aniracetam & Others 22:00 – Phenylpiracetam Power 26:37 – Who Benefits & Stacking 32:25 – Safety & Regulation 36:41 – Starter Protocol & Takeaways See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Elle Russ chats about some of the biggest misconceptions around thyroid hormone dosing. From T4-only and T4/T3 combinations to NDT, direct T3, slow-release T3, dose splitting, timing, and sublingual dosing, Elle breaks down why there is no one-size-fits-all protocol—and why people often mistakenly apply T3-only dosing rules to completely different thyroid hormone protocols. She also shares her own experience having used T3-only, T4/T3 combinations, and navigating reverse T3 issues over the years. If you've ever wondered whether you need to dose multiple times a day, whether your thyroid medication should be split, or why a dosing strategy that works beautifully for one person makes absolutely no sense for another, this episode clears up the confusion. Learn more about Elle Russ HERE

We are backkk, I have survived the plague and it's time for a big Q&A to get us back in the groove!I hope you enjoy, and don't forget to share and tag me on insta @emma.currivan xoxo⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠CHAT TO ME ABOUT COACHING ON WHATSAPP⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠JOIN MY PATREON HERE⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ - just 5.99 a month hehe xTo submit a question for a Q&A episode⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠click here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Don't forget to subscribe to my YouTube channel!⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Catch you in the next one xoChapters00:00 Emma's birthday and recent travel reflections01:47 Health scare and recovery from food poisoning03:57 Rome trip highlights and food experiences07:02 Review of a viral Rome rooftop bar09:49 Post-travel illness and recovery process13:00 Handling nutrition around major surgery16:06 Growing a coaching business and industry saturation20:05 The importance of personal branding in coaching24:10 Client communication and check-in timing30:06 Advice on nutrition, supplements, and training35:12 Balancing lifestyle and bodybuilding coaching39:58 Reflections on family, personal life, and future plans44:50 Q&A on various fitness and coaching topics

Emily Werner, PhD, RD, CSSD, IFNCP is Team Dietitian for the Philadelphia 76ers (NBA) and Philadelphia Flyers (NHL), and Nutrition Affairs Sport Lead at Timeline. Dr. Emily joins Dr. Mike to unpack postbiotics, urolithin A, and why mitochondrial health matters for pro athletes and everyday people alike, digging into the real research behind Timeline's Mitopure and why chasing $200K gadgets rarely beats getting the fundamentals right. Expect to learn what a postbiotic actually is and how urolithin A differs from other supplements, why old-school and new-school sports dietitians disagree on peptides and supplement fads, how chronic undereating quietly undermines performance in women's sports, what the current human performance research on urolithin A actually shows, how Mitopure is dosed and why urolithin A can't be reliably food-sourced, and why product quality and manufacturing integrity matter more than marketing claims, and much more. Connect with Emily: Website: https://www.eateliteperform.com/ Instagram: @emilywerner34 LinkedIn: https://www.linkedin.com/in/emily-n-werner-phd-rd-cssd-ifncp-4a820a97/ Episodes you'll enjoy next: #377 — Methylene Blue for Mitochondria & Performance: Benefits, Dosing & Risks with Dr. Scott Sherr: Listen here #382 — Creatine for Muscle, Bone, Brain & Longevity (Plus Caffeine, Dosing, and Safety) with Dr. Darren Candow: Listen here Episode Timestamps: 2:21 Welcome & introductions 6:09 What is a postbiotic? Pre-, pro-, and postbiotics explained 7:09 Urolithin A: the postbiotic behind Mitopure 8:19 How Emily started consulting for Timeline 10:11 Old-school vs. new-school sports dietitians on supplements 13:53 Peptides, anecdata, and why athletes ignore the data 20:05 The hardest lesson: letting go when clients won't listen 21:15 Money, ego, and athletes chasing $200K wellness gadgets 24:53 Chronic undereating in women's sports 30:48 Nutrition's real job: keeping athletes available to play 33:19 Inside Mitopure: Timeline's flagship urolithin A product 35:06 Mitochondria, mitophagy, and why they matter as we age 38:16 Diet, fasting, and exercise as natural mitophagy triggers 43:36 What the performance research on urolithin A actually shows 53:19 Aging, aerobic capacity, and Emily's 101-year-old grandma 55:40 Mitopure dosing: how much urolithin A and when to take it 57:14 Why urolithin A can't be food-sourced (and can't be faked) 1:03:19 Why product quality and integrity matter in supplements Get the Daily Fitness Insider newsletter (free): https://www.miketnelson.com/newsletter

CJC-1295 is one of the most purchased peptides in the research space. It is also one of the least understood.Most people pick it up because a friend told them to. Then they run into side effects nobody warned them about. Around 70% get injection site reactions. Plenty get flushing, hives, or headaches. That does not make it a bad peptide. It just means you should know what you are walking into.In this one I cover both versions, DAC and no DAC, and where I land on each. We get into how GHRH analogs signal the pituitary to release growth hormone. I explain the four amino acid swaps and why they matter. We also talk about the halted 2006 trial and the death that still follows this compound around.Then we get practical. Dosing tiers, why fasting is not optional here, cycle length, and the order I would introduce ipamorelin. I also cover who should skip CJC entirely and what to track while you run it.Human data on CJC is thin compared to tesamorelin. I say so where it matters.If you are running it already or thinking about it, this is the full picture.⚠️ For research and entertainment purposes only. ⚠️

Is Medication Right for Your OCD? A Psychiatrist Breaks Down SSRIs, Dosing, and What Actually WorksIf you've ever wondered whether medication could help your OCD or anxiety, or you've tried an SSRI and felt like "nothing worked," this episode is for you. Matt Codde, LCSW sits down with Dr. Melissa Quinn, a triple board certified psychiatrist who specializes in OCD treatment, for a full breakdown of how medication actually works, why so many people are underdosed, and how medication and therapy work together rather than against each other.Dr. Quinn walks through SSRIs, clomipramine, augmentation strategies, and common myths (including the cannabis conversation you don't want to miss), while Matt reframes ERP through the Restored Minds lens of emotional integration rather than symptom elimination.

In this episode of the Habit-Based Lifestyle Podcast, host Jesse Ewell welcomes Dr. Solomon Jon, a board-certified family medicine physician and expert in peptides. Dr. Jon shares his personal journey from traditional medicine to exploring the world of peptides and wellness. He discusses the challenges he faced in the medical community regarding the acceptance of peptides, the common mistakes people make when using them, and the importance of understanding dosing and sourcing. The conversation emphasizes the need for a balanced approach to health, integrating both traditional and innovative methods for optimal wellness. In this conversation, Jesse and Solomon dive into the complexities of weight loss, the importance of support systems, and the evolving landscape of peptide therapies.  They discuss the potential future of peptides in healthcare, the challenges posed by big pharma, and the need for more regulations. The conversation also touches on personal health habits and the impact of various peptides on health and wellness. Takeaways: • Dr. Solomon Jon transitioned from traditional medicine to wellness after personal health challenges. • Peptides can offer significant benefits for health and wellness, but they require proper understanding and application. • The medical community is often skeptical about peptides due to a lack of evidence and education. • Common mistakes in using peptides include not understanding dosing and sourcing. • It's essential to identify personal health goals before using peptides. • Dosing for peptides is not standardized, making it crucial to work with knowledgeable providers. • The future of peptides in medicine may involve more regulation and acceptance in the medical community. • Personal experience in health can enhance a provider's credibility and effectiveness. • Education and open-mindedness are vital in the evolving landscape of health and wellness. • The conversation around peptides is just beginning, and more professionals need to engage with this topic. Weight loss requires more than just a quick fix; habits matter. • Support systems are crucial for successful weight management. • Peptides can be life-changing when used correctly. • The FDA's role will shape the future of peptide therapies. • Big pharma faces challenges in patenting natural compounds. • The health industry resembles a 'Wild West' scenario. • Foundational health practices are essential for effective treatment. • GLPs show promise in metabolic health and weight loss. • Oral delivery of peptides could revolutionize their use. • Education and awareness about peptides are vital for practitioners. Reach out to Solomon Jon on Instagram Learn more about Jesse though the following links: HBL Lifestyle Secrets Group on Facebook Personal Website HBL Website Instagram Email

What if the GLP-1 conversation is bigger than weight loss? In this episode, I sit down with McCall McPherson, PA-C, thyroid expert and founder of Modern Thyroid Clinic. We have a candid, nuanced discussion about GLP-1 receptor agonists, the clinical questions that extend beyond the scale, and why safety, nutrition, medication sourcing, and individualized follow-up must stay at the center of the conversation. McCall shares the clinical observations that led her team to explore low-dose approaches with some thyroid patients, including questions around inflammation and autoimmune symptoms. We also discuss what is established, what remains under study, and why an episode conversation should never replace a personal discussion with a licensed clinician. Important clinical note: The episode includes discussion of microdosing and possible anti-inflammatory applications. These ideas may be outside FDA-approved uses and are not a plan for self-treatment. Do not start, stop, split, or change a prescription medicine without guidance from a qualified prescriber.

Most men would rather suffer in silence than admit they have a problem in the bedroom —Let's change that. On this episode of Taboo To Truth, I sat down with Jeff Abraham, CEO of Promescent, to talk about one of the most common yet least discussed issues in men's sexual health: premature ejaculation. We get into the real clinical definition of PE, why the "arousal gap" between men and women makes this a near-universal issue, and why anxiety — not selfishness — is usually driving the problem. Jeff breaks down the physiological and psychological causes of PE, why shame keeps so many men from seeking help, and why over 4,000 doctors recommend Promescent's Delay Spray. We also cover how the product actually works, how to use it correctly, dosing and titration, safety data from 3 million bottles sold, and how it compares to Viagra. Jeff gets personal too, sharing his own story of turning 69, how porn distorts expectations for young men, and the reality of the refractory period as we age. We close out talking about female pleasure, non-ejaculatory orgasms, and why using every tool available in the bedroom is nothing to be ashamed of. This is a candid, funny, and genuinely useful conversation for any man — or any partner of a man — who wants better sex and less anxiety about it.Use this link for 15% off Delay Spray: https://promescent.sjv.io/QY44bYIn This Episode:00:00 — The Silent Struggle Millions of Men Face 00:33 — Podcast Intro & Meet Your Host 01:05 — Welcome Jeff Abraham, CEO of Promescent 02:10 — What Really Counts as Premature Ejaculation 04:15 — The Arousal Gap & Why Anxiety Kills Intimacy 06:45 — Physical vs. Psychological Causes of PE 09:00 — Breaking the Stigma Around Men's Sexual Health 11:00 — Kegels, Combo Therapy & Why Urologists Trust Promescent 14:00 — The Old (Bad) Solutions: SSRIs and Numbing Creams 16:30 — Treating PE Step by Step & Weaning Off 19:30 — How Jeff Discovered Promescent (Origin Story) 22:30 — The Eutectic Formula That Changes Everything 25:00 — How to Use the Delay Spray: Application & Timing 27:30 — Dosing, Titration & Finding Your Sweet Spot 29:30 — Is It Safe? 3 Million Bottles, Zero Red Flags 31:00 — Promescent vs. Viagra & Doctors' Favorite Combo 33:30 — Does Age or Ethnicity Affect PE Rates? 35:15 — The PE-ED Connection & the Fragile Male Ego 37:00 — Jeff's Personal Story: Aging, Porn & Regret 38:30 — Where to Find Promescent, Discount CodeTo watch the video version of this episode, head over to YouTube!About the Guest:Jeff Abraham is the CEO of Promescent, a leading sexual wellness brand focused on making intimacy solutions more accessible and effective. After discovering a groundbreaking treatment for premature ejaculation developed by urologist Dr. Ronald Gilbert, Jeff invested in the product and became the majority owner, launching the company's flagship Delay Spray.Connect with Jeff Abraham:Website: https://www.promescent.comInstagram: https://www.facebook.com/Promescent/Delay Spray: https://promescent.sjv.io/QY44bYAbout the host: Karen Bigman, a Sexual Health Alliance Certified Sex Educator, Life, and Menopause Coach, tackles the often-taboo subject of sexuality with a straightforward and candid approach. We explore the intricacies of sex during perimenopause, post-menopause, and andropause, offering insights and support for all those experiencing these transformative phases.This podcast is not intended to give medical advice. Karen Bigman is not a medical professional. For any medical questions or issues, please visit your licensed medical provider.Looking for some fresh perspective on sex in midlife? You can find me here:Email: karen@taboototruth.comWebsite: https://www.taboototruth.com/Instagram: https://www.instagram.com/taboototruthYouTube: https://www.youtube.com/@taboototruthpodcastSubstack: https://karenbigman.substack.comWant more Taboo To Truth? Join the community HERELINKS, RESOURCES, EXCLUSIVE VIP DISCOUNTS & FREEBIES

Hosts: Ed Jones (Owner – Nutrition World) & Clint Powell A variety of topics all related to living a healthy life Presented by: Nutrition World www.nutritionw.com  Broadcasting from the Nooga Dentistry Studio www.noogadentistry.com Production of: Whitfield Media Group www.vitalhealthradio.com Title: Oral Peptides for Appetite & Weight Loss, What Your Phase Angle Means for Your Cellular Health [0:00:00] Intro, Events Tease of the episode's themes: Segment 2: peptides and weight loss. Segment 3: phase angle and cellular health. Lung Coach event at Nutrition World – August 22 Mobile screening for early lung cancer detection. Emphasis that stage 1–2 lung cancer is often curable, stage 4 is not. Calcium score used to estimate plaque burden in arteries. Ed notes ~12 reasons for plaque formation, while most physicians focus on ~3. Mentions Dr. Kurt Dearing's book “Beyond Cholesterol”, covering broader causes of plaque. Financial health talk – August 22 (~11 AM) Michael E, financial planner, giving a free lecture on financial stability. Ed's point: two major life disruptors are declining health and declining finances, and they influence each other. Health Fair – October 24 Described as possibly the biggest health fair in the region. Features reps, free samples, circus‑like but “happy” atmosphere. [0:04:10] Restaurant Talk Light banter about Ed being a restaurant connoisseur and creature of habit. Restaurant recommendations via Ed's employee Fallon: Second Amendment / Second American (downtown). Hello Monty (special but reasonably priced menu). Ed's oxalate/joint pain story: Eating Purely Elizabeth cereal (high in oxalates: chia and other ingredients) triggered severe return of joint pain Discussion that some “healthy” foods can be nutritious but not healthy for everyone, especially for those sensitive to oxalates. Ed references his free oxalate ebook at theholisticnavigator.com and believes oxalates contributed to: His double hip replacement. Feeling old from age 50–65. Mentions OxyGuard supplement (recently restocked) and using 4 capsules/day to help clear excess oxalates (not as a license to keep eating high‑oxalate foods). Quick shout‑out to local farmers from Virginia End Farm selling at Nutrition World on Wednesdays (12–4), and that they've listened to every show. [0:8:55] Tease: Phase Angle & Seca Machine Ed previews Dr. Kurt Dearing's later segment on phase angle: A single number reflecting resilience and proximity to optimal health.. Mention of Be Well Labs / BeginwithLabs.com – Body Blueprint: Advanced lab panel: 50+ predictive health indicators. Pitch: more than a standard physical, actionable results. Price example: $275 vs typical $500, highlighting savings. [0:13:35] Segment Intro: Peptides & Weight Loss Framing: Peptides as one of the hottest trends in 47 years of Ed's experience. Shift from grey‑market injectables to safe, effective oral peptide powders. Ed has seen impressive feedback on an oral peptide powder for weight loss in early customers. [0:13:47] What Are Peptides? Protein basics: Proteins are long chains of amino acids essential for structure, function, and regulation. Peptide defined: A shorter chain of amino acids broken off from a larger protein. Lego analogy: Individual Legos = amino acids. Tall tower of Legos = full protein. Kid knocks tower over; a small intact stack (~8 Legos) that falls off = peptide. Each peptide has a “fingerprint” determined by: Length (how many amino acids/Legos). Sequence (order: e.g., red–red–blue–blue vs red–blue–red–blue). Processing (how it was broken off or created). Clarified: peptides are not primarily for fixing protein deficiency, but more for targeted signaling effects in the body. [0:20:52] Yeast‑Derived Oral Peptide for Metabolism & Drug Comparisons Endogenous peptides: made naturally inside the body. Exogenous peptides: introduced from outside (drug injections, supplements). Ozempic / GLP‑1 drugs: Yes, Ozempic is a peptide. These drugs are lab‑made peptides made to mimic natural body peptides. Peptides are not synthetic drugs in concept; they are peptide structures the body uses, though drugs are engineered. Focus on Ancient Nutrition “Active Peptide for Metabolism”: Contains a yeast peptide derived from Saccharomyces cerevisiae (brewer's yeast), broken from a larger yeast protein. Mechanism & effects: Influences hunger and satiety signaling: Increases leptin (satiety hormone). Decreases ghrelin (hunger hormone). Reported benefits: Reduced hunger and cravings (including boredom eating). Weight loss primarily from fat mass, not muscle mass. Comparison with GLP‑1 injections (semaglutide, etc.): Injections often cause muscle loss (e.g., “Ozempic face,” loss of facial muscle/fat). Yeast peptide research shows fat‑centric weight loss. Clinical results quoted: After 2 months, average daily caloric intake decreased by ~600 calories. Leads to meaningful weight loss, depending on baseline intake and muscle mass. [0:24:25] Dosing, Timing, Stacking & Safety Considerations How to take it: Once daily, typically in the morning to curb cravings throughout the day. Users report: easier recognition of fullness during meals. Stacking with cortisol peptide product: Ancient Nutrition also has a cortisol‑active peptide capsule for stress support. Same amount of yeast peptide per serving; research supports doubling the yeast peptide dose, so: You can use the metabolism powder + cortisol peptide together. Stress, cortisol, and weight: Chronic stress and high cortisol promote fat gain. Stacking stress support + appetite control may help body composition. Onset of effect: Reagan reports she personally noticed benefits around 2 weeks (quicker than many supplements that take 60–90 days). Cost & practicality: Approx cost around $50 for 30 days. Positioned as a cost‑effective alternative or complement to expensive injections. Side effects vs injectables: Reagan's hospital experience with GLP‑1 side effects (e.g., gastroparesis, impaired gastric motility, some requiring tube feeds or IV nutrition). Oral yeast peptide described as gentler, working with natural processes, not “forcing” the system. [0:30:09] Yeast Source, Candida Concerns & Usage Notes Yeast strain: Saccharomyces cerevisiae (not S. boulardii, and not pathogenic/candida). Clarifications: Will not cause yeast infections. Will not feed candida overgrowth. Taste & preparation: Chocolate flavor described as surprisingly good, even for those picky about chocolate. Temperature-sensitive: Must be mixed with cool liquid (NOT hot coffee/tea or hot beverages). Leaving it in high heat (e.g., hot car) can degrade activity. [0:36:03] Segment Intro: Phase Angle & Seca Scan with Dr. Kurt Dearing Discussion of: Seca medical‑grade bioelectrical impedance analysis (BIA) machine (~$12,000). It's commonly in hospitals/clinics, but rarely publicly accessible; Nutrition World and Be Well Labs both have one. Dr. Dearing's consult package: Includes consult + Seca scan + follow‑up visit + follow‑up Seca scan (~$195, promo if listeners mention the show). [0:37:35] What Is Phase Angle? (Deep Dive into Measurement & Meaning) What the Seca scan measures: Total body fat and visceral fat. Muscle mass (overall and by body segment). Phase angle (key focus). Phase angle basics: BIA sends low‑level alternating electrical currents through the body. The phase shift (time/angle difference) between current and voltage is measured. That phase shift = phase angle. Higher phase angle → healthier cell membranes, better cellular integrity, more muscle mass, better hydration. Lower phase angle → often malnutrition, chronic disease, frailty; can be used in dialysis, cancer patients, etc., to predict outcomes. Used as a longevity biomarker: Akin to an “EKG of your cells”. Can function as an early indicator for overall health trajectory, barring accidents Dr. Dearing's personal story: First scan categorized him as “bronze” on Seca's scale: Levels: None → Bronze → Silver → Gold → Platinum. Motivated him to increase strength training and eating healthy. Subsequent scan: improved from bronze → gold. Ed's anecdote: Friend and gym member Fred now tests as platinum, after sustained gym and nutrition efforts. Phase angle as a guide: If results are poor, that's a signal to upgrade the plan (diet, exercise, supplements). If phase angle improves (e.g., 4 → 5), it proves the plan is working, beyond just “feeling” better. [0:43:47] How to Improve Phase Angle (Practical Protocols) Key drivers and interventions: 1. Strength Training & Exercise Primary recommendation: resistance/strength training to build muscle mass. 2. Adequate Protein Ed's guideline: ~1 gram of protein per pound of body weight (men; women can often target ~¾ g per pound). Protein shakes often needed to hit targets. 3. Hydration & Electrolytes Proper cellular hydration improves phase angle. Maintain consistent fluid intake and electrolyte balance (sodium, potassium, magnesium). Avoid excessive diuretics/water pills. Dehydration causes phase angle to drop sharply. 4. Inflammation Control Systemic inflammation lowers phase angle and contributes to chronic disease. Tools: Anti‑inflammatory diet (Mediterranean‑style, high in omega‑3s). Omega‑3 fatty acids. Curcumin. Vitamin D optimization. Also includes sleep quality and stress management. 5. Foundational “Core Four” Supplements (Nutrition World concept) Covering: magnesium, zinc, vitamin D, B vitamins, etc., as baseline. 6. Targeted Add‑ons Creatine (supports muscle and cell energy). HMB (beta‑hydroxy beta‑methylbutyrate) – often paired with creatine. CoQ10 (mitochondrial and cellular energy). Phosphatidylcholine / BodyBio PC – to improve cell membrane integrity. [0:52:45] Closing Reflections Ed reads and comments on an article by Dr. Sircus about: Many doctors being “misaligned”: intellectually capable but no longer listening. Critique of: Over‑reliance on credentials. Under‑reliance on open‑mindedness and corrections. Emphasis that many clinicians are excellent listeners and deeply caring, but that institutional habits can discourage listening.  The post Radio Show / Podcast – July 26, 2026 first appeared on Vital Health Radio.

In this video, I explain what AMPK is and its central role in metabolism and aging. Discover how AMPK activation can lead to significant fat loss and improved metabolic function. We also explore the extensive AMPK benefits, including enhanced cellular respiration and reduced oxidative stress, offering valuable longevity tips.CHAPTERS00:00 Why ATX-304 Matters for Energy & Longevity00:48 What AMPK Is and Why It Controls Metabolism01:48 What ATX-304 Actually Does02:58 The Potential Health Benefits04:24 ATX-304 vs PQQ and CoQ1005:18 Safety, Dosing, and What We Don't Know06:13 Final Thoughts on ATX-304Connect with Dr. Greg JonesGet 10% off your first order at Dr. Jones Supplement Store when you join the email list. https://drjonessupplements.com/Instagram: @doctorjones_doctorjones Enovative Wellness Center: https://enovativewellness.com/

How do you build stronger, more powerful footballers when there is barely enough time to recover between matches?In this episode, Nick Grantham shares how his approach to strength and conditioning has evolved after years working in elite Olympic sport and the English Premier League. The conversation explores why strength remains a cornerstone of elite football performance, how to individualize training across a congested season, and why chasing the "perfect" gym session may no longer be the answer.Nick also explains the concept of nano dosing, using small but meaningful strength exposures throughout the week, while discussing minimum effective dose, player monitoring, injury mitigation, and balancing long term athletic development with match readiness.Interested in learning more about the latest developments in endurance performance and sports science? Subscribe to the HIIT Science email list for updates on new research, courses, and educational opportunities.Today's speakers:Dr Martin Buchheit https://martin-buchheit.net/    Nick Graham https://www.linkedin.com/in/nickgranthamconsultancyltd/Athletica Uhttps://youtube.com/playlist?list=PLu7L8NU083obOOZnkl9qd1lxr5zfVKTkL&si=YkGXTSQsJcYBUPiD

All Links Here: https://hunterwilliamshealth.com/linksIpamorelin might be the best peptide to start with if you have never touched growth hormone.In this masterclass I break down why. It pushes out your own growth hormone without dragging cortisol, prolactin, or hunger along with it. That clean profile is the whole reason it is still around.I go through what it actually does in the body. It starts at the ghrelin receptor and ends with IGF-1, which carries the real benefits. Better sleep, better recovery, better skin and hair over time.I cover who this is for. Anyone over 35, and especially women in their 40s and 50s who have never tried a growth hormone peptide.Then I get practical. Dosing tiers, the threshold where more stops helping, and how to cycle it. Plus how to stack it with CJC-1295 NoDAC the right way. I also explain why I have people run ipamorelin alone before adding anything.If you are on a GLP-1, this pairs really well and helps protect your muscle.We do not have a mountain of human trial data here. I am honest about that. But the safety record is mature and the anecdotal results are strong.If you are curious about growth hormone, start here.

How have 3 years of real-world experience with complement inhibition changed when and how retina specialists treat GA? In episode 2 of the GA in Practice miniseries on New Retina Radio, moderator Geeta Lalwani, MD, and panelists Murtaza Adam, MD, and Carl Danzig, MD, examine how referral patterns, safety data, and extension study findings have shifted their approach to early treatment. The group then works through a hypothetical case of an active 73-year-old patient with extrafoveal GA and intermediate AMD in the fellow eye, exploring how lesion characteristics, CNV risk counseling, and months-long travel schedules factor into the treatment decision.

S-Ketamine is now part of the TCCC pharmacopeia; you'd better understand how to use it. Dennis sits down with Pat — a veteran military anesthetist, former Danish Special Operations medical leader, and decades-long ketamine expert — for a deep dive into S-Ketamine. From its development and real-world use in austere environments (including Afghan war wounded and British Field Hospital MERT ops) to practical dosing, side effect management, and why it outperforms morphine in many trauma scenarios, this conversation delivers battle-tested wisdom for medics, PAs, nurses, and SOF operators.Pat shares hands-on lessons from hospital, military, and austere settings: achieving the "thousand-yard stare," managing emergence phenomena, combining with regional anesthesia, IM/IN/rectal routes, and why ketamine shines for hemodynamically unstable patients, refractory asthma, and more. They also discuss training pitfalls, the value of hands-on experience (including vet collaboration ideas), and cultural differences in patient responses.Key Takeaways:S-Ketamine is roughly twice as potent as racemic ketamine — use ~half the dose, but expect the same onset, duration, and side-effect profile (with potentially milder psych effects at mid-doses).Excellent for analgesia and procedural sedation in austere settings; superior hemodynamic stability compared to opioids in hypovolemic trauma patients.S-Ketamine is now included in the 2026 TCCC updates — critical knowledge for every combat medic and austere provider.Practical tips: titrate slowly IV, watch for nystagmus/thousand-yard stare, prepare for emergence with low-dose midazolam + patience, consider regional blocks to reduce opioid needs.Training emphasis: objective endpoints, patient monitoring, planning for side effects, and real-world experience over rote memorization.Whether you're running a prolonged field care scenario, managing a screaming femur fracture, or preparing for the next deployment, this episode arms you with actionable strategies.Subscribe, share with your team, and visit prolongedfieldcare.org for free resources, downloads, and more. PFC Coffee links in the description — fuel for the fight.#ProlongedFieldCare #Ketamine #AustereMedicine #TCCC #SOFMedicineChapters:00:00 Intro & Sponsors + Guest Welcome (Pat's Background)03:30 S-Ketamine vs Racemic Ketamine: Potency, Dosing, and Myths08:45 Early Experiences – Afghan War Wounded & Mass Casualty Ketamine Sedation14:20 Sedation Technique: Thousand-Yard Stare, Nystagmus, Airway Management, Atropine20:10 Emergence Phenomena, Cultural Differences, and Midazolam Management25:50 Battlefield Analgesia – Ketamine Superiority Over Morphine (Bastion Study)30:40 Dosing Strategies: IV Titration, IM/IN/Rectal Routes, Bioavailability37:15 Training Realities – Avoiding the “Middle Zone,” Objective Endpoints, Vet Collaboration43:30 Regional Anesthesia + Ketamine Synergy (Chester Buckenmaier Influence)47:20 Special Populations: Kids, Hemodynamically Unstable, Asthma, Head Trauma, Seizures53:10 Practical Tips for New Providers, Mission Planning, and Austere Pearls58:40 Closing Thoughts & ResourcesFor more content, go to ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠www.prolongedfieldcare.org⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Consider supporting us: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠patreon.com/ProlongedFieldCareCollective⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ or ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠www.lobocoffeeco.com/product-page/prolonged-field-care⁠⁠

Urolithin A (Mitopure) and Mitochondrial Renewal--Muscle, Immune, and Skin Benefits: Jen Scheinman, MS, RDN, CDN, Director of Science Communications at Timeline details urolithin A and Timeline's branded supplement Mitopure. She describes urolithin A's discovery through pomegranate research and worm studies showing a 45% lifespan increase. She discusses human research including improved walking distance and clinical outcomes in muscle endurance and strength. Urolithin A is presented as supporting mitochondrial health by promoting mitophagy—recycling damaged mitochondria—distinct from other mitochondrial supports like CoQ10 and NAD precursors. They explain most people cannot produce enough urolithin A from foods because only 30–40% convert precursors via the microbiome and it would require about six cups of pomegranate juice daily. Dosing discussed is 500–1,000 mg/day via gummies, capsules, or powder, with effects developing over months. She reviews emerging research on immune aging, preclinical work on brain and neurodegenerative conditions, and topical urolithin A for skin.

Sarah Kennedy of Calocurb explains why food noise spikes in perimenopause: falling estrogen raises cravings while the hindbrain overrides forebrain willpower under stress or poor sleep. She contrasts natural appetite hormones (GLP-1, GIP, CCK, PYY) with pharmaceutical GLP-1 agonists, which run at roughly 3,000% physiological levels versus the body's natural 300% rise - explaining rebound hunger after stopping injectables. Calocurb, a hops-derived bitter compound, stimulates a 600% natural hormone rise for an 18% average calorie reduction. WHAT YOU'LL LEARN Why food noise isn't a willpower problem, and what's actually happening in your hindbrain versus your forebrain when cravings take over How declining estrogen in perimenopause changes your calorie needs even as cravings increase What GLP-1, GIP, CCK, and PYY actually do in your body, and how they differ from each other How pharmaceutical GLP-1 agonists compare to your body's own natural hormone levels, and what that gap means for nutrient intake Why coming off a GLP-1 medication can trigger intense rebound hunger, and what's happening hormonally during that transition How bitter taste receptors throughout your gut influence appetite signaling, and why this evolutionary mechanism matters What role the luteal phase, travel, and sleep deprivation play in cravings, and how timing strategies can offset them TIMESTAMPS 00:00 - Intro  00:58 - Willpower vs. Biology: The Hindbrain-Forebrain Battle Driving Cravings  04:58 - GLP-1 Explained: How Natural Appetite Hormones Actually Work 10:21 – Supraphysiological Dosing on GLP-1 Drugs and Nutrient Sufficiency Risks  14:03 – Bitter Taste Receptors: The Gut-Brain Mechanism Behind Appetite Suppression  16:58 – Managing Mindless Snacking, Grazing, and the "Licks, Sips, and Dips" Problem  22:06 – Using Appetite Support Strategically During Weight Loss Plateaus  26:26 – Onboarding, Dosing, and Managing Digestive Side Effects  28:13 – Blood Sugar Regulation and New Clinical Research on Weight Loss Outcomes  30:51 – Why You Must Transition Off GLP-1s Strategically to Avoid Rebound Weight Gain  36:53 – Mood, Motivation, and the Liberating Effect of Quieting Food Noise  39:44 – Closing Thoughts VALUABLE RESOURCES• Take the BioSyncing Quiz to help you understand what's actually happening in your body — and how to fix it.

In this episode of the TCOYD Podcast, Dr. Steve Edelman is joined by pediatric endocrinologist Dr. Anna Cymbaluk, along with Philip and his father Jim, to discuss the recent FDA approval of Afrezza inhaled insulin for children and adolescents living with type 1 diabetes. Dr. Cymbaluk served as an investigator on the INHALE-1 trial, while Philip participated in the study himself, providing a unique real-world perspective on what it is like to transition from injections to inhaled insulin, and Philip's dad, Jim provided the parent perspective as well as addressed parental concerns that might have arisen.The conversation focuses on the INHALE-1 study and the unmet challenges that continue to exist around mealtime insulin dosing in pediatric diabetes care. Dr. Cymbaluk reviews the trial design, glucose outcomes, safety data, patient satisfaction findings, and the practical realities of introducing inhaled insulin into everyday diabetes management. Philip and Jim share how Afrezza impacted school, sports, social situations, and the day-to-day burden of diabetes, particularly around pre-bolusing, corrections, and avoiding multiple injections throughout the day.Dr. Edelman and Dr. Cymbaluk also explore how Afrezza is dosed, how inhaled insulin differs from injected insulin, who may be a good candidate, and where it may fit alongside pumps and automated insulin delivery (AID) systems. For families looking for more flexibility, fewer mealtime barriers, and another option in the diabetes toolbox, this episode provides an honest look at the benefits, limitations, and real-world experience of inhaled insulin in children and teens.Key Topics• The FDA approval of Afrezza for children and adolescents living with type 1 diabetes• The design and results of the INHALE-1 pediatric clinical trial• Patient satisfaction and quality-of-life outcomes from the study• The challenges of pre-bolusing and mealtime insulin management in children and teens• How inhaled insulin compares to traditional mealtime injections• Dosing strategies, cartridge sizes, and insulin conversion considerations• Using Afrezza for corrections, meals, and post-meal dosing• The role of continuous glucose monitoring (CGM) when using inhaled insulin• Safety findings, lung-function monitoring, and cough management• Who may be a good candidate for Afrezza—and who may not be• Benefits for active children, athletes, and those participating in sports• Social situations, injection avoidance, and reducing the burden of diabetes management• Using Afrezza alongside insulin pumps and automated insulin delivery (AID) systems• The importance of having more treatment options to individualize diabetes careSupported by an unrestricted educational grant from MannKind CorporationSubscribe for practical diabetes management tips, technology updates, and treatment breakthroughs that help people with diabetes live healthier, more flexible lives.More diabetes resources:Website: tcoyd.orgBlog: tcoyd.org/blogPodcast: tcoydthepodcast.transistor.fmInstagram: / tcoydFacebook: / tcoydStay connected! Sign up for our monthly newsletter here!Support TCOYD's educational programs: tcoyd.org/donate ★ Support this podcast ★

Curious whether peptide therapy is the missing piece in your wellness routine, or just another overhyped trend? This episode breaks down what these powerful chemical messengers do in the body, from healing injuries to balancing brain chemistry, cellular energy and more, plus why sourcing and dosing make all the difference.Host Jenn Trepeck sits down with Dr. Aleksandra Gajer to explore BPC 157, brain-supporting peptides, and mitochondrial function, while tackling how to use peptides safely, who should avoid them, and why they work best as a tool rather than a magic fix-all.What You Will Learn in This Episode:✅ How peptide therapy acts as a chemical messenger system that supports the body's own healing pathways rather than overriding them✅ Why BPC 157 has become one of the most talked about peptides for tendon repair, gut healing, and recovery✅ How neuroinflammation, not just neurotransmitter imbalance, may be driving anxiety, depression, and brain fog✅ The role of mitochondrial function and insulin sensitivity in body composition, energy, and long-term metabolic healthThe Salad With a Side of Fries podcast, hosted by Jenn Trepeck, explores real-life wellness and weight-loss topics, debunking myths, misinformation, and flawed science surrounding nutrition and the food industry. Let's dive into wellness and weight loss for real life, including drinking, eating out, and skipping the grocery store.TIMESTAMPS:00:00 Dr. Aleksandra Gajer's path from emergency medicine to proactive, personalized healthcare08:04 Defining peptides and their relationship to inflammation and healing10:04 Exploring BPC 157 for tendon injury, gut healing, and tissue recovery12:31 How peptides support autoimmune conditions by regulating immune balance15:35 Brain peptides Selank and Semax and the truth behind the neuroinflammation link to anxiety18:57 Understanding mitochondrial function, fatigue, and brain fog as cellular energy issues20:35 MOTS-c, insulin sensitivity, and the connection to body composition22:18 Why peptides work best as a tool, not a replacement for healthy habits26:03 Safe peptide sourcing, endotoxins, and who should avoid peptide therapy33:54 Hormone health, dosing strategy, and cycling peptides for sustainable resultsKEY TAKEAWAYS:

In this episode, we explore how the future of wellness is shifting away from endless optimization and toward a more personalized, less-is-more approach to health. We share our current favorite biohacks, discuss the benefits of an alcohol-free lifestyle, cycle syncing, peptides, and emerging technologies like the Ohm Lamp and stem cell therapies. We also unpack the growing backlash against "over-optimization" and why the next era of biohacking will prioritize precision, simplicity, and long-term resilience. Tune in for an inspiring conversation about aging well, supporting future generations, and why 2026 may be the most exciting time yet to take charge of your health.SHOW NOTES:0:40 Welcome to the podcast!2:15 Lauren's favorite biohack right now5:50 Foundational travel hacks6:40 Renee's rescue8:52 Renee's favorite biohack right now9:58 Benefits of no alcohol11:48 PhaseApp for cycle syncing15:31 The Ohm Lamp17:05 Revisiting peptides18:49 Comparison to microdosing23:29 RFK & new regulations24:43 Solving the problem of aging29:35 Excitement for the future of health32:15 Stem cells34:45 Supporting the senior population37:17 The era of ‘less' supplements44:35 Backlash trend of “over-optimization” 49:03 Major/minor signs on OURA50:33 Wellness centers53:26 Final advice & recap55:32 Thanks for tuning in!RESOURCES:Phase App - code: BIOHACKERBABESOhm Lamp - code: BIOHACKERBABESEllie MD PeptidesPeptide QuizEp 346: Addiction & Peptides with Samantha LanderEp 339: GLP-1 Dosing with Jay CampbellBiolongevity Labs - Discount code: BIOHACKERBABESEp 331: GP1 Biology & Calacurb with Sarah KennedyCalocurb - Discount code: RENEE10Dr. Vincent GiampapaBeam Minerals - Discount code: BIOHACKERBABES for 20% offKion Essential Amino Acids - Discount code: BIOBABES for 15% offEp 349: Airway Health & Snoring with Dr. Gene SambataroSupport this podcast at — https://redcircle.com/biohacker-babes-podcast/donationsAdvertising Inquiries: https://redcircle.com/brands

Ketamine Therapy, MDMA, Psilocybin, and the Science of Psychedelic Assisted Healing Most people struggling with depression, anxiety, and trauma have never felt safe in their nervous system, and the treatments they have been prescribed are making that worse. This episode breaks down the neuroscience of psychedelic therapy, why ketamine is the safest and most accessible starting point, how MDMA triggers a BDNF dependent pathway that repairs trauma all the way down to the epigenetic code, and why your antidepressant may be blocking the very brain states required for real healing. -Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR -Order Dr. Rabin's Book ‘A Simple Guide to Being Alive': https://apolloneuro.com/pages/a-simple-guide-to-being-alive Host Dave Asprey sits down with Dr. Dave Rabin, MD, PhD, a senior research scientist at the Florida Institute for Human and Machine Cognition, Executive Director of The Board of Medicine, and co-founder and Chief Medical Officer of Apollo Neuroscience. Dr. Rabin received his MD and PhD in neuroscience from Albany Medical College and specialized in psychiatry at the University of Pittsburgh Medical Center. He has spent 20 years studying chronic stress and non-invasive therapies for treatment-resistant illness, and his primary research on MDMA assisted therapy for severe PTSD has demonstrated that trauma can be reversed at the epigenetic level, offering a genuine path to a cure. His upcoming book A Simple Guide to Being Alive publishes June 1, 2026 and is a science-backed manual for anyone who has ever felt overwhelmed by the modern world. Dave and Dr. Rabin break down why nearly 50% of people prescribed psychiatric medication never achieve remission, why SSRIs and SNRIs physically block the brain states required for emotional healing, and why the FDA rejected MDMA therapy after three trials showed an 88% response rate. They dig into the exact BDNF pathway that makes MDMA and ketamine so transformative, how psychedelics amplify safety learning in the amygdala at the molecular level, and why trauma passes down up to 14 generations through epigenetic code that can now be measured and repaired. They also cover why your breathing rate at the doctor's office is already a stress signal nobody is reading, how your smartphone puts your nervous system into a chronic fear state before you even get out of bed, and why ketamine is the right starting point for anyone curious about psychedelic therapy right now. You'll Learn: Why nearly 50% of psychiatric patients never get better and what treatment-resistant actually means How ketamine therapy works, why it is legal in every state, and why it is the safest place to start The exact BDNF pathway through which MDMA repairs fear extinction in the amygdala How MDMA assisted therapy produces measurable epigenetic repair of the cortisol receptor gene damaged by trauma Why SSRIs and SNRIs block the insula mediated brain states required for real emotional healing Why combining serotonergic psychedelics with SSRIs puts you at risk of life-threatening serotonin syndrome Why trauma passes down up to 14 generations and what you can do to stop the cycle now Why smartphones put your nervous system into a toxic overstimulation state before the day even starts How the FDA rejected MDMA therapy after 88% of patients responded and who paid to make that happen Thank you to our sponsors! - Qualia | If you want to take the guesswork out of maintaining high NAD+ levels as you age, go to www.qualialife.com/daveNAD to get clinically proven Qualia NAD+ backed by a 100 day money back guarantee and code DAVENAD at checkout gets you an extra 15% off. - iRestore | Reverse hair loss at www.irestore.com/DAVE and get exclusive savings on the iRestore Elite, use code DAVE - OneSkin | For a limited time, try OneSkin with 15% off at oneskin.co/DAVE. - LMNT | Right now you can get a free 8-count Sample Pack of LMNT's most popular drink mix flavors with any purchase at drinkLMNT.com/dave Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights inhealth, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: Dave Rabin, Dr. Dave Rabin, Apollo Neuroscience, A Simple Guide to Being Alive, ketamine therapy, MDMA assisted therapy, psilocybin therapy, psychedelic assisted therapy, treatment-resistant depression, treatment-resistant mental illness, BDNF pathway, fear extinction amygdala, vagus nerve activation, trauma epigenetics, cortisol receptor gene, epigenetic repair, serotonin syndrome, SSRI alternatives, MDMA BDNF, ketamine BDNF, nervous system safety, autonomic nervous system, parasympathetic nervous system, generational trauma, trauma self-trust, MAPS MDMA trial, FDA MDMA rejection, pharmaceutical interference MDMA, breathing rate stress, smartphone nervous system, Apollo Neuro wearable, Board of Medicine, theboardofmedicine.org, insula cortex, psychedelic safety protocol, ketamine legal therapy, MDMA 88 percent, bottom-up learning psychedelics, trauma fractured self-trust, 14 generations trauma, stress breathing range Resources: • Order Dr. Rabin's Book ‘A Simple Guide to Being Alive': https://apolloneuro.com/pages/a-simple-guide-to-being-alive • Purchase Dr. Fotuhi's New Book The Invincible Brain: https://a.co/d/0iHCgPpL • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 00:00 – Trailer 01:34 – Dave Rabin Introduction 05:01 – Psychedelics and Psychiatry 08:35 – Psychedelic Safety and Dosing 14:53 – Serotonin Syndrome Warning 21:17 – Vagus Nerve and Safety 27:36 – Smartphones and Chronic Stress 34:18 – Defining Trauma 38:00 – Trauma and Epigenetics 40:23 – MDMA Cortisol Gene Repair 44:44 – Therapy vs. Medicine Alone 49:15 – FDA MDMA Rejection 55:35 – Ketamine Personal Experience 59:15 – Closing and Book Recommendation See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Most men think erectile dysfunction is a bedroom problem and low testosterone is just a fact of getting older. This roundtable makes the case that both are early warning lights for your heart, your metabolism, and your long-term health and that ignoring them can cost you a decade.In this episode, Dr. Gabrielle Lyon sits down with urologists and men's health specialists Dr. Mohit Khera, Dr. Larry Lipshultz, and Dr. Tobias Köhler to discuss:Why a 35-year-old with ED carries a ~15% risk of heart attack or stroke within 7 years, ~3.5x the risk of depression, and ~30% odds of diabetes or prediabetes and why a prescription alone misses all of itWhy "age-related" testosterone decline is largely a misnomer: a healthy man shouldn't drop significantly with age, so falling T usually signals something reversible underneathHow testosterone became the single best blood marker of a man's overall health, and the case for annual screening that almost no man getsWhat the TRAVERSE trial changed when the FDA removed testosterone's cardiovascular warning in 2025, debunking the prostate-cancer and heart-attack fearsThe 2-minute monthly self-exam every man should do to catch testicular cancer early, when it's ~99% curableIf you've been told your symptoms are "just aging" or you love a man who refuses to see a doctor. This conversation shows you how to read the signals your body gives long before a crisis hits.Thank you to our sponsors:Body Health - Use the code LYON20 to get 20% off your first order https://bit.ly/4efgBuMTimeline - Get 20% off your Mitopure order at https://bit.ly/49LSbYzBranch Basics - Save 15% at https://bit.ly/4uuw4x3 with code DRLYONExplore More from Dr. Gabrielle LyonPremium Podcast Subscription: Ad-free episodes, key takeaway summaries, exclusive Q&A, and behind-the-scenes content https://foreverstrong.supercast.comWeekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon's clinical team https://drgabriellelyon.com/new-patient-inquiry/Find Dr. Larry Lipshultz at:Instagram: https://www.instagram.com/lipshultzmd?igsh=NTc4MTIwNjQ2YQ==Website: https://www.larrylipshultz.com/YouTube: https://www.youtube.com/@DrsAmyandLarryFind Dr. Tobias KohlerInstagram: https://www.instagram.com/tobiaskohlermd?igsh=NTc4MTIwNjQ2YQ==X: https://x.com/sexhealthmd?s=11Find Dr. Mohit KheraInstagram: https://www.instagram.com/drmohitkhera?igsh=NTc4MTIwNjQ2YQ%3D%3DX: https://x.com/DrMohitKheraWebsite: https://drmohitkhera.com/Connect with Dr. Gabrielle Lyon:Instagram: https://www.instagram.com/drgabriellelyon/TikTok: @drgabriellelyonX (Twitter): https://x.com/drgabriellelyonFacebook: https://www.facebook.com/doctorgabriellelyonChapters00:00 - Introduction01:30 - What doctors got wrong about testosterone05:05 - The prostate cancer myth, debunked07:12 - The best marker of a man's health11:51 - Is age-related decline actually real?14:15 - How obesity crushes testosterone18:11 - Testosterone and reversing diabetes20:06 - GLP-1 versus testosterone25:20 - What "low testosterone" really means29:05 - Dosing, CAG repeats, and microdosing42:34 - The TRAVERSE trial and FDA reversal47:10 - The prostate saturation point56:49 - Peptides, explained01:03:00 - Why ED is a check engine light01:08:26 - The desert of men's health care01:11:06 - The case for annual screening01:16:45 - Varicoceles and male fertility01:20:03 - How to check for testicular cancer01:26:44 - Final advice for menIf you found this episode valuable, share it with someone who would benefit from it.Disclaimers: This episode includes paid sponsorships.The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.

In this episode: Mark creates DOSsier, a system for retro PC gaming. Martin replaces his editor (again), this time with Fresh Alan creates a new app for event attendance. You can send your feedback via show@linuxmatters.sh or the Contact Form. If you’d like to hang out with other listeners and share your feedback with the community, you can join us on: The Linux Matters Chatters on Telegram. The Linux Matters Subreddit. If you enjoy the show, please consider supporting us.

Red light therapy is now at Target. It's on Amazon by the thousands. And with that explosion comes a mountain of marketing claims, spec sheet arguments, and consumer confusion that has Freddie and Scott Kennedy — founder of Light Path LED and one of the most science-grounded voices in photobiomodulation — more motivated than ever to cut through the noise. In this fifth conversation across seven years together, they break down exactly what happens at the cellular level when red and near-infrared light hits your body: how cytochrome C oxidase absorbs photons, why that turbine in your mitochondria spins faster, how nitric oxide release drives vasodilation and blood flow, and why the gap between 700 and 800 nanometers is essentially a dead zone. They also get real about power, irradiance, pulsing frequencies, and why the best panel in the world won't save a business model built on charging $100 a session for red light alone. The second half of this episode is a full product walkthrough of what Scott has been building — including the new Titan, a six-foot full-body panel with an electric adjustable stand designed to deliver what $60,000 red light beds do at a fraction of the cost, and the TLC dork cap — three years in development, covering the full head, jaw, cervical lymph nodes, and occipital region with red, near-infrared, and blue light at 10 and 40Hz pulsing. Freddie and Scott also explore the torch, intranasal red light delivery, dental and gum applications, stacking red light with peptides for injection site activation, and the honest conversation about what a sustainable red light business model actually looks like in 2026. Use code BEAUTIFULLYBROKEN at lightpathled.com for a discount.   Episode Highlights   [00:00] – Red light therapy goes mainstream and why consumer confusion is exploding [02:10] – Scott's dental laser background and how he discovered photobiomodulation [04:32] – Why red light supports the body instead of directly “treating” conditions [06:22] – How light increases ATP, blood flow, oxygenation, and downstream cellular benefits [10:00] – The difference between red light and near infrared light [12:11] – What happens at the cellular level with mitochondria, cytochrome C oxidase, and nitric oxide [18:45] – Why irradiance and power claims can be misleading for consumers [24:32] – Therapeutic dose, joules, timing, and why more is not always better [30:53] – The problem with too many wavelengths and marketing-based panel design [36:05] – Lightpath LED's wavelength choices, pulsing features, and near infrared focus [44:11] – The Titan panel and why Scott designed a simpler full-body red light option [45:51] – The Dork Cap, blue blockers, torch attachments, and practical red light tools for daily use   Upgrade Your Health   LightPathLED: https://lightpathled.pxf.io/c/3438432/2059835/25794 Code: beautifullybroken   MaxGen Labs: https://maxgenlabs.com/BEAUTIFULLYBROKEN Code: beautifullybroken   The Biological Blueprint Course: https://www.beautifullybroken.world/biological-blueprint Earn 200 in BitCoin + Change your health   BEAM Minerals: http://beamminerals.com/beautifullybroken Code: BEAUTIFULLYBROKEN   Silver Biotics Wound Healing Gel: https://bit.ly/3JnxyDD 30% off with Code: BEAUTIFULLYBROKEN   StemRegen: https://www.stemregen.co/products/stemregen?_ef_transaction_id=&oid=1&affid=52 Code: beautifullybroken CONNECT WITH FREDDIEWork with Me: https://www.beautifullybroken.world/biological-blueprintWebsite and Store: (http://www.beautifullybroken.world) Instagram: (https://www.instagram.com/freddie.kimmelYouTube: https://www.youtube.com/@beautifullybrokenworld Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

With so many supplements marketed to runners, it's easy to wonder what's actually worth taking. In this episode, we cut through the noise and focus on a few supplements that have strong research behind them—while emphasizing that no supplement can replace consistent training, good nutrition, quality sleep, and proper recovery.We break down the Three Cs: Carbohydrates, Creatine, and Caffeine.First, we discuss why many runners are underfueling and how carbohydrates play a critical role in performance, recovery, and endurance. Next, we explore creatine monohydrate, one of the most researched supplements available, and its benefits for strength, recovery, and overall health. Finally, we cover caffeine, including how it can improve performance, common dosing guidelines, and why personal tolerance matters.We also briefly touch on vitamin D, magnesium, omega-3s, and collagen, and discuss when they may be worth considering.In This Episode:Why supplements should never replace the fundamentalsHow carbohydrates support performance and recoveryThe benefits of creatine for runnersHow caffeine can enhance enduranceWhen other supplements may be helpfulAvoiding the optimization trap and keeping things simple03:53 The Three Cs 09:59 Fueling During Runs14:29 Carb Targets And Gut Training20:16 Women Over 40 And Carbs25:03 Adjusting Fuel To Effort28:31 Creatine Explained41:14 Monohydrate and Daily Dose43:25 Caffeine Performance Basics46:23 Dosing and GI Timing47:33 Metabolism and Jitters50:29 Sleep and Tolerance Tradeoffs54:12 Race Day Caffeine Rules56:54 Vitamin D Testing59:34 Magnesium for Cramps01:03:38 Omega 3 Benefits01:05:26 Collagen Versus ProteinGain access to my new secret podcast, Unbreakable: The Runner's Guide To Injury-Proofing Your Body After 40. Click here: https://www.realliferunners.com/secretJoin the Team! -->  https://www.realliferunners.com/team Thanks for Listening!!Be sure to hit FOLLOW on Apple Podcasts, Spotify, or your favorite podcast player Leave a review on Apple Podcasts. Your ratings and reviews really help and we read each one!Come find us on Instagram and say hi! Don't forget: The information on this website is not intended to treat or diagnose any medical condition or to provide medical advice. It is intended for general education in the areas of health and wellness. All information contained in this site is intended to be educational in nature. Nothing should be considered medical advice for your specific situation.

Most herbal dosing strategies fail during acute infections, not because the herbs are wrong, but because the dosage, frequency, and timing are wrong. In this video, Sajah Popham from the School of Evolutionary Herbalism walks you through the four biggest mistakes herbalists make when treating infections, and how to create protocols that lead to better outcomes. Here's what you'll learn: Why herbal dosing for acute infections is different from chronic care The four most common mistakes people make when taking herbs during illness Why low-dose strategies often fail in the treatment of acute infections Suggested dosage and frequency guidelines for acute herbal protocols Why herbs need time and consistency to build up and be effective How to think about various herb classes as part of your treatment protocol The importance of organ-system specificity and tissue state energetics Why herbs don't work the same way antibiotics do, and how to manage client expectations Treating lingering symptoms  Supportive lifestyle practices that improve recovery outcomes Warning signs that indicate it may be time to seek medical attention   If you want to dive even deeper into this kind of information, you might really like our FREE Vitalist Herbalism Mini-course.  Join the waitlist to get the FREE workshop when it starts on June 15, 2026: http://www.evolutionaryherbalism.com/vitalist-herbalism-mini-course/waitlist/   ———————————— CONNECT WITH SAJAH AND WHITNEY ———————————— To get free in depth mini-courses and videos, visit our blog at:  http://www.evolutionaryherbalism.com   Get daily inspiration and plant wisdom on our Facebook and Instagram channels: http://www.facebook.com/EvolutionaryHerbalism https://www.instagram.com/evolutionary_herbalism/   Be sure to subscribe to our YouTube Channel: https://www.youtube.com/channel/UCyP63opAmcpIAQg1M9ShNSQ   Get a free 5-week course when you buy a copy of the book, Evolutionary Herbalism: https://www.evolutionaryherbalism.com/evolutionary-herbalism-book/   Shop our herbal products:  https://naturasophiaspagyrics.com/   ———————————— ABOUT THE PLANT PATH ———————————— The Plant Path is a window into the world of herbal medicine. With perspectives gleaned from traditional Western herbalism, Ayurveda, Chinese Medicine, Alchemy, Medical Astrology, and traditional cultures from around the world, The Plant Path provides unique insights, skills and strategies for the practice of true holistic herbalism. From clinical to spiritual perspectives, we don't just focus on what herbs are "good for," but rather who they are as intelligent beings, and how we can work with them to heal us physically and consciously evolve.   ———————————— ABOUT SAJAH ———————————— Sajah Popham is the author of Evolutionary Herbalism and the founder of the School of Evolutionary Herbalism, where he trains herbalists in a holistic system of plant medicine that encompasses clinical Western herbalism, medical astrology, Ayurveda, and spagyric alchemy. His mission is to develop a comprehensive approach that balances the science and spirituality of plant medicine, focusing on using plants to heal and rejuvenate the body, clarify the mind, open the heart, and support the development of the soul. This is only achieved through understanding and working with the chemical, energetic, and spiritual properties of the plants. His teachings embody a heartfelt respect, honor and reverence for the vast intelligence of plants in a way that empowers us to look deeper into the nature of our medicines and ourselves. He lives on a homestead in the foothills of Mt. Baker Washington with his wife Whitney where he teaches, consults clients, and prepares spagyric herbal medicines.    ———————————— WANT TO FEATURE US ON YOUR PODCAST? ———————————— If you'd like to interview Sajah or Whitney to be on your podcast, click here to fill out an interview request form. If Whitney is facilitating an interview:   ———————————— ABOUT WHITNEY ———————————— Whitney Popham is an herbal practitioner and the co-founder of The School of Evolutionary Herbalism and Organic Unity. Her calling to plant medicine began from a deep passion for activism and a vision for creating healing and positive change in the world. She has devoted her life to that vision by being a humble vessel for the plants to touch people's lives and bring more healing and beauty into the world.   Through her own health challenges and struggles, she experienced the profound healing gifts of plant medicines and then committed her life to helping others reach vibrant levels of health. She specializes in digestive health in her clinical practice through working with herbal medicine, nutrition and lifestyle coaching. Her true gift is in listening to the plants through intuition and vision, which she uses to help her clients with healing on the emotional, psychological, spiritual, as well as physical levels of health.  

Needle-Free Peptides, US Manufacturing, BPC-157, Thymosin Alpha-1, GLP-1s, Microneedle Patches, and How to Avoid Contaminated Peptides Peptides are one of the most powerful tools in biohacking and anti-aging medicine, and until now, most people couldn't access them safely, legally, or without a needle. This episode changes that. -Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR -Go to Aminoinnovations.com and use “asprey20” for a discount through the next 7 days Host Dave Asprey sits down with Justin Kirkland, a longevity medicine expert with over 30 years in drug development and pharmaceutical innovation. Kirkland holds multiple drug synthesis and formulation patents, has founded multiple pharmaceutical companies, and is one of the few people in the world manufacturing peptides entirely on US soil, controlling every step of the synthesis process from raw amino acids to finished product. If you want to understand what is really inside your peptides and why it matters for your longevity and human performance, he is the person to listen to. Dave and Justin go deep on why most peptides on the gray market contain dangerous residual compounds that can spike liver enzymes and cause real harm, why Chinese-sourced APIs are not always what they claim to be, and how a new generation of needle-free delivery systems including microneedle patches and auto-injectors is making peptide therapy accessible to anyone serious about longevity and human performance. They also cover how AI and functional medicine are converging to make peptide protocols personalized based on genetics and microbiome status, why the thymus gland is one of the most overlooked anti-aging targets in the body, and what the suppression of peptide research reveals about who really controls your access to health tools. You Will Learn: Why many gray market peptides contain toxic residual acids that damage the liver and how to identify clean products How microneedle patches and auto-injectors are replacing traditional injections for peptide delivery Which peptides are most effective for longevity, immune system repair, and human performance including BPC-157, Thymosin Alpha-1, and growth hormone secretagogues Why your genetics and gut microbiome determine whether a peptide will work for you at all How the thymus gland controls your immune system and why it disappears by your mid-20s What the suppression of peptide research tells you about Big Pharma's control over your supplement and nootropics access Why US-manufactured peptides represent a new standard for safety and quality in biohacking How AI is transforming personalized peptide protocols in functional medicine Which peptides are overhyped and which ones actually move the needle on anti-aging and recovery How to store, mix, and dose peptides correctly to avoid the mistakes most people using them are making right now Thank you to our sponsors! - Danger Coffee | Grab yours at DangerCoffee.comand use code DAVEPOD at checkout for 15% off. - The One Device | Use code DAVE for $10 off at theonedevice.com/dave - Fatty15 is on a mission to support Healthy Aging for All, including all ages and stages of life. You can get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com DAVE and using code DAVE at checkout. - ENERGYbits | If you want a simpler, smarter way to support your body… this is it. Head to ENERGYbits.com and use code ASPREY for 20% off your order. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights inhealth, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: Justin Kirkland, peptides, needle-free peptides, microneedle patch, BPC-157, Thymosin Alpha-1, ipamorelin, CJC-1295, PT-141, KPV peptide, Dihexa, growth hormone secretagogue, peptide purity, TFA contamination, gray market peptides, US manufactured peptides, oral peptides, transdermal delivery, thymus gland, anti-aging, biohacking, longevity, functional medicine, peptide auto-injector, compounding pharmacy Resources: • Go to Aminoinnovations.com and use “asprey20” for a discount through the next 7 days • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 00:00 – Intro & Guest Welcome 01:55 – Censorship & Platform Bans 06:20 – Peptide Science & Bioavailability 07:20 – Delivery Methods 14:30 – Supply Chain & US Manufacturing 17:01 – Manufacturing Risks & Contamination 24:43 – Peptide Stacks 28:41 – Immune Peptides & Thymus 30:57 – Overhyped Peptides 41:00 – Alternative Delivery (Patches, Nasal, Rectal) 47:25 – Side Effects & Risk 50:30 – Mixing & Storage Tips 54:05 – Wrap-Up & Where to Buy See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

You do the work. You train, you sleep, you eat well, you manage stress. And yet your joints still ache, recovery takes longer, and something just feels harder than it used to.I sit down with David Watumull, co-founder and CEO of AX3, to talk about astaxanthin, a naturally occurring antioxidant he has spent his entire career studying, one that most people have never heard of despite having more than 4,000 peer-reviewed papers and 100 human clinical trials behind it.This is not a conversation about the latest wellness trend. It's a deep look at the science of oxidative stress, chronic inflammation, and what actually happens inside your cells when the damage accumulates faster than your body can repair it.What we explore:- Why astaxanthin is categorically different from vitamins C and E, and how it works at every layer of the cell without ever becoming pro-oxidant.- How chronic inflammation starts with oxidative stress upstream, and why blocking it at the source is safer than suppressing the immune response after the fact.- Why this ingredient was one of only five agents in a 20-year NIH-funded program to extend mammalian lifespan by over 10 percent while also showing health span benefits.- How astaxanthin protects joints, muscles, and mitochondrial energy production, and what the data on competitive cyclists actually demonstrates.- What to look for in a supplement, why bioavailability determines whether you absorb anything at all, and how to build astaxanthin into a foundational daily stack.Chapters: 00:00 Intro03:30 Why Astaxanthin Isn't Like Other Antioxidants07:14 The Algae Origins of Astaxanthin11:22 Salmon, the Food Chain, and Nature's Design15:00 From Pharma Research to Supplement18:21 The NIH Longevity Study Explained23:15 mTOR, FOXO3, and the Aging Pathways29:10 Safe Anti-Inflammatory for Joints and Athletes35:15 Brain Protection and the Blood-Brain Barrier38:02 Skin Health and Sun Damage from the Inside45:00 Redox Balance and Liver Protection48:35 Mitochondria, Energy, and Endurance Performance53:00 How to Stack Astaxanthin with Other Supplements57:10 Dosing, Bioavailability, and What Sets AX3 Apart01:07:00 Why David Watumull Went All-In on One IngredientAbout David Watumull:David Watumull is the co-founder and CEO of AX3, a supplement company built on more than two decades of astaxanthin research. He was introduced to the ingredient as a teenager working on algae ponds on the Big Island of Hawaii, and has spent his career advancing its science through pharmaceutical-grade manufacturing, NIH-funded longevity studies, and peer-reviewed cardiovascular research. His work sits at the intersection of rigorous science and practical supplementation, and it shows.Connect with David Watumull:Instagram: https://www.instagram.com/davewatumull–This episode is sponsored by:AX3: Visit ax3.life and use code GABBY for 20% OFF your first orderWebsite: https://www.ax3.lifeInstagram: https://www.instagram.com/ax3.life–The Gabby Reece ShowThis is where I have real conversations with the people I find most worth listening to: scientists, athletes, coaches, parents, and thinkers who are doing the hard work of building a life that holds up over time. No hacks. No quick fixes. Just honest, practical conversations about performance, longevity, relationships, and what it actually takes to show up well at every age.If you are here, you probably already know that health is not a destination. It is how you live. I am glad you are along for it.Connect with Gabby Reece:Instagram: https://www.instagram.com/gabbyreece/TikTok: https://www.tiktok.com/@gabbyreeceofficialWebsite: https://gabriellereece.comPlease note that this episode may contain paid endorsements and advertisements for products and services. Individuals on the show may have a direct or indirect financial interest in products or services referred to in this episode.Produced by Dear Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Most people think tracking their protein is enough. The science says what your body actually craves is something far more specific and the person making that argument spent 23 years inside legacy media watching the wellness industry sell women everything from "bikini body in two weeks" to canned protein soda. In this episode, I sit down with Liz Plosser, former Editor in Chief of Women's Health, where she oversaw brands reaching 44 million women. We break down why the nine essential amino acids are what your body is really after when you chase protein, why BCAAs are only a fraction of the picture, and why a study found four of the top six creatine gummies on Amazon contained zero creatine. Liz also opens up about her own supplement stack, her shift from endurance running to heavy lifting, and makes the case that testing instead of guessing is one of the most empowering moves you can make for your health. Then we go deep on the science most people get wrong: why aging women struggle to pull amino acids from food, how essential aminos protect lean muscle even on rest days and for those on GLP-1s, the new research on high-dose creatine for sleep deprivation and Alzheimer's, and why collagen may not deserve the hype. We also cover the menopause misinformation epidemic, the 2002 hormone study that terrified the world, and what Liz puts in her own morning protocol. This conversation will completely change how you think about protein, what you supplement, and how you fuel your brain and body. *Reduce your risk of Alzheimer's with my science-backed protocol for women 30+:*https://go.neuroathletics.com.au/youtube-sales-page Subscribe to The Neuro Experience for evidence-based conversations at the intersection of brain science, longevity, and performance. _____ *TOPICS DISCUSSED*(00:00:00) Intro: The Protein Myth and Why Amino Acids Are What Your Body Really Wants (00:00:56) Protein, Amino Acids, and How Much You Actually Need (00:03:23) The Nine Essential Amino Acids: The Real Building Blocks (00:06:03) BCAAs vs EAAs: Why a Subset Isn't Enough (00:11:50) 23 Years in Wellness Media: What Liz Saw Change (00:14:18) The Menopause Conversation and Why It Exploded (00:23:17) Kion Aminos, Timing, and Whether It Counts Toward Your 100g (00:26:46) Liz's Daily Routine: Aminos, Creatine, and the Morning Glass of Water (00:27:42) Can You Take Aminos While Fasting? (00:29:50) Do Aminos Preserve Lean Mass on Rest Days and on GLP-1s? (00:36:19) Leaving Legacy Media and Finding a New Mission (00:39:14) The New Creatine Research: Sleep, Dosing, and Alzheimer's (00:43:24) How Creatine Reaches the Brain and the Case for 10 Grams (00:44:48) Creatine for Mood and Depression (00:46:12) Collagen: Does It Actually Deserve the Hype? (00:49:40) The Creatine Gummy Scandal: Four of Six With Zero Creatine (00:51:27) Coffee, Cans, and Why Bioavailability Matters (00:54:50) Creatine, Electrolytes, and the 1990s Bodybuilding Hack (00:57:54) Liz's Morning Protocol and Owning Your AM _______ *Thank you to our sponsors*Function Health: https://www.functionhealth.com/louisanicolaTimeline: https://www.timeline.com/partners/neuro-athleticsAirDoctor: https://www.AirDoctorPro.com use promo code NEURO for up to $300 offQualia Life: https://www.qualialife.com/Neuro for an additional 15% off on top of the 50%BASED Bodyworks: https://basedbodyworks.com/ and use code NEURO for 20% off _______ I'm Louisa Nicola - clinical neurophysiologist - Alzheimer's prevention specialist - founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention.If you're committed to optimizing your brain- reducing Alzheimer's risk - and staying mentally sharp for life, you're in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0Instagram: https://www.in... Learn more about your ad choices. Visit megaphone.fm/adchoices

Most people think tracking their protein is enough. The science says what your body actually craves is something far more specific and the person making that argument spent 23 years inside legacy media watching the wellness industry sell women everything from "bikini body in two weeks" to canned protein soda. In this episode, I sit down with Liz Plosser, former Editor in Chief of Women's Health, where she oversaw brands reaching 44 million women. We break down why the nine essential amino acids are what your body is really after when you chase protein, why BCAAs are only a fraction of the picture, and why a study found four of the top six creatine gummies on Amazon contained zero creatine. Liz also opens up about her own supplement stack, her shift from endurance running to heavy lifting, and makes the case that testing instead of guessing is one of the most empowering moves you can make for your health. Then we go deep on the science most people get wrong: why aging women struggle to pull amino acids from food, how essential aminos protect lean muscle even on rest days and for those on GLP-1s, the new research on high-dose creatine for sleep deprivation and Alzheimer's, and why collagen may not deserve the hype. We also cover the menopause misinformation epidemic, the 2002 hormone study that terrified the world, and what Liz puts in her own morning protocol. This conversation will completely change how you think about protein, what you supplement, and how you fuel your brain and body. Reduce your risk of Alzheimer's with my science-backed protocol for women 30+: https://go.neuroathletics.com.au/youtube-sales-page Subscribe to The Neuro Experience for evidence-based conversations at the intersection of brain science, longevity, and performance. _____ TOPICS DISCUSSED 00:00 Intro: The Protein Myth and Why Amino Acids Are What Your Body Really Wants 00:56 Protein, Amino Acids, and How Much You Actually Need 03:23 The Nine Essential Amino Acids: The Real Building Blocks 06:03 BCAAs vs EAAs: Why a Subset Isn't Enough 11:50 23 Years in Wellness Media: What Liz Saw Change 14:18 The Menopause Conversation and Why It Exploded 23:17 Kion Aminos, Timing, and Whether It Counts Toward Your 100g 26:46 Liz's Daily Routine: Aminos, Creatine, and the Morning Glass of Water 27:42 Can You Take Aminos While Fasting? 29:50 Do Aminos Preserve Lean Mass on Rest Days and on GLP-1s? 36:19 Leaving Legacy Media and Finding a New Mission 39:14 The New Creatine Research: Sleep, Dosing, and Alzheimer's 43:24 How Creatine Reaches the Brain and the Case for 10 Grams 44:48 Creatine for Mood and Depression 46:12 Collagen: Does It Actually Deserve the Hype? 49:40 The Creatine Gummy Scandal: Four of Six With Zero Creatine 51:27 Coffee, Cans, and Why Bioavailability Matters 54:50 Creatine, Electrolytes, and the 1990s Bodybuilding Hack 57:54 Liz's Morning Protocol and Owning Your AM _______ Thank you to our sponsors Function Health: https://www.functionhealth.com/louisanicola Timeline: https://www.timeline.com/partners/neuro-athletics AirDoctor: https://www.AirDoctorPro.com use promo code NEURO for up to $300 off Qualia Life: https://www.qualialife.com/Neuro for an additional 15% off on top of the 50% BASED Bodyworks: https://basedbodyworks.com/ and use code NEURO for 20% off _______ I'm Louisa Nicola - clinical neurophysiologist - Alzheimer's prevention specialist - founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain- reducing Alzheimer's risk - and staying mentally sharp for life, you're in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Learn more about your ad choices. Visit megaphone.fm/adchoices

The ancient fruit sitting in your grocery store right now outperforms rapamycin, rivals caloric restriction, and triggers a cellular cleanup process that most longevity scientists did not even know existed until a lab changed everything 18 years ago. -Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR -Go to timeline.com/Dave or just use code ‘Dave' to get 20% off your next order. Host Dave Asprey sits down with Chris Rinsch, co-founder and President of Timeline Longevity and a PhD cell biologist who has spent nearly two decades doing pharmaceutical quality clinical research on one of the most underrated longevity molecules on earth. Before founding Timeline in 2007, Rinsch worked in venture capital investing in pioneering life sciences companies and in biotechnology developing cell-based therapies at Swiss biotech company ISOTIS SA. He has authored original publications in Nature Medicine, Nature Metabolism, JAMA Open, and Cell Reports Medicine, and holds internationally filed and granted patents on urolithin A. This is the first time a Timeline co-founder has appeared on the show. Together, Dave and Chris break down the full science of urolithin A, the postbiotic compound unlocked from pomegranate by gut bacteria, and why it triggers mitophagy to clear out damaged mitochondria and replace them with high-functioning ones. They cover why only 30 to 40 percent of people can produce urolithin A from food alone, how one month of supplementation measurably improved immune cell populations in people aged 50 to 70, and why Dave has stacked this into his daily longevity protocol alongside NAD precursors and nootropics for years. If you are serious about biohacking your mitochondria, extending healthspan, and doing smarter not harder longevity work, this episode delivers the deep science to back it up. You'll Learn: Why urolithin A outperforms rapamycin in worm lifespan studies and rivals caloric restriction at 45 percent life extension How mitophagy works, why it declines with age, and why it is one of the most important anti-aging mechanisms in the body Why eating pomegranates or taking cheap pomegranate extract does not work for most people and what to take instead How one month of MitoPure improved natural killer cells, CD8 T naive cells, and reduced inflammation in adults aged 50 to 70 Why mitochondria are central to metabolism, brain optimization, immune function, cardiovascular health, and skin aging How Timeline's topical urolithin A produced statistically significant reductions in fine lines and wrinkles after eight weeks Why Dave considers this one of the most clinically validated supplements in his longevity stack alongside NAD and fasting protocols How L'Oreal became a Timeline investor after confirming the mitochondrial science was unlike anything in their existing ingredient library What the XPRIZE Healthspan competition is targeting and why Timeline is competing to reverse biological aging by 10 to 20 years Why the future of functional medicine will require a mitochondrial blood test and how close we are to having one Thank you to our sponsors! - EMR-Tek | https://www.emr-tek.com/DAVE and use code DAVE - Calroy | Go to Calroy.com/DAVE for exclusive discounts on Arterosil HP, Vascanox HP and all Calroy products. - Neuronic | Go to www.neuronic.online Code DAVE for $100 off - ENERGYbits | If you want a simpler, smarter way to support your body… this is it. Head to ENERGYbits.com and use code ASPREY for 20% off your order. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights inhealth, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: Chris Rinsch, Timeline Longevity, MitoPure, urolithin A, mitochondria, mitophagy, pomegranate, elagitannins, postbiotic, gut microbiome, longevity, anti-aging, healthspan, biohacking, supplements, human performance, metabolism, mitochondrial health, cellular health, autophagy, natural killer cells, immune health, inflammation, NAD, rapamycin, caloric restriction, muscle endurance, collagen, skin aging, fine lines, wrinkles, topical skincare, L'Oreal, XPRIZE Healthspan, Nature Aging, clinical trials, longevity stack, brain optimization, cardiovascular health, biological age, aging clock, fasting, nootropics, functional medicine, Dave Asprey, polyphenols, microbiome diversity Resources: • Go to timeline.com/Dave or just use code ‘Dave' to get 20% off your next order. • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 00:00 – Trailer 00:37 – Intro 03:57 – Pomegranates 10:03 – Discovering Urolithin A & Mitophagy 20:50 – Science vs. Pomegranate Supplements 25:24 – Topical Skincare Science 26:09 – L'Oreal Partnership & Skin Results 33:38 – 15 Clinical Studies & XPRIZE 43:50 – Nature Aging Immune Study 49:22 – Dosing & Daily Routine 51:29 – Future of Mitochondrial Health See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.