Podcasts about Dosing

Charley Wininger returns to Adventures Through The Mind to discuss How To Host An MDMA Group Roll Our discussions starts with a quick general overview of MDMA before shifting into a thorough exploration of group rolls—what they are, what they can offer us individually and collectively, who to invite, who not to invite, where to do it, what to include, what to exclude, safety protocols, and just a whole number of things. Enjoy!  

In today's episode, Vanessa reveals the shocking new human research on two of the most powerful and science-backed supplements for women's fat loss, muscle tone, metabolic health, skin rejuvenation, and longevity: creatine and collagen. You'll discover why creatine is no longer just a gym supplement, and how groundbreaking new data shows collagen may actually influence biological age. This episode is packed with cutting-edge insights every woman needs to hear. Timeline Mitopure Gummies — The #1 Urolithin A supplement for energy and healthy aging, now in delicious strawberry gummies. Get 20% off at timeline.com/vanessa In this episode, you'll learn: ✨ The shocking results from new human studies on creatine and collagen ✨ Why creatine is one of the most underrated supplements for women, especially in perimenopause and post-menopause ✨ How creatine enhances fat loss, muscle tone, metabolic rate, cognition, and sleep-deprivation resilience ✨ The simple, evidence-based dose of creatine that works for women — and why Vanessa uses Puori creatine ✨ The brand new 2025 human trial showing collagen's key amino acids reduced biological age by an average of 1.4 years ✨ How collagen improves skin elasticity, hydration, wrinkles, nails, hair, joints, and connective tissue strength ✨ Why stacking creatine + collagen is a powerful strategy for fat loss, lean muscle retention, skin health, and healthy aging If you want a clear, science-backed guide to creatine and collagen — including exactly how to dose and use them for optimal results — this episode is for you.

In this episode of the PFC Podcast, Dr. Van Wyk discusses the latest updates in traumatic brain injury (TBI) management, focusing on insights from the CRASH-3 trial, the use of TXA, hypertonic saline, and sodium bicarbonate. He emphasizes the importance of monitoring intracranial pressure and the potential for surgical interventions in austere environments. The conversation also touches on the controversial topic of seizure prophylaxis and end-of-life considerations in TBI care.TakeawaysDr. Van Wyk is a neurologist with extensive experience in TBI management.The CRASH-3 trial provides insights into TXA's effectiveness in TBI patients.Moderate TBI patients may benefit more from TXA than severe cases.Dosing protocols for TXA are still under discussion, with traditional methods being preferred.Hypertonic saline is recommended for TBI management, but higher concentrations may be beneficial.Sodium bicarbonate can be an effective alternative for managing ICP.Prophylactic use of hypertonic saline is debated but may be reasonable in certain cases.Seizure prophylaxis is not universally recommended but can prevent complications in TBI patients.Monitoring ICP through optic nerve sheath diameter is evolving, with trends being more useful than absolute values.Surgical interventions for TBI may be necessary in austere environments, but should be approached with caution.Chapters00:00 Introduction to Traumatic Brain Injury Management02:00 Insights from the CRASH-3 Trial06:43 Dosing Protocols for TXA in TBI11:28 Hypertonic Saline: Concentration and Administration17:21 Alternative Treatments for Increased ICP22:58 Prophylactic Sodium Management in TBI25:17 Seizure Prophylaxis in Traumatic Brain Injury30:04 Monitoring Intracranial Pressure Non-Invasively35:17 Surgical Interventions for Elevated ICP42:10 End-of-Life Decisions in Severe TBIFor more content, go to ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠www.prolongedfieldcare.org⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Consider supporting us: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠patreon.com/ProlongedFieldCareCollective⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ or ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠www.lobocoffeeco.com/product-page/prolonged-field-care⁠

Very Low Nicotine Content Cigarettes for Smoking Cessation: Examining a Facilitated Extinction Approach and Dosing Schedule Drug and Alcohol Dependence Very low nicotine cigarettes (VLNC, 0.4 mg nicotine/g tobacco) have been shown to reduce smoking behavior when compared to normal nicotine cigarettes (NNC,17 mg nicotine/g tobacco). Participants (n=208) were randomly assigned to 4 experimental groups, immediate versus gradual (over 5 weeks) transition to VLNC, and standard counseling versus facilitated extinction counseling (weekly for 5 weeks). Facilitated extinction had participants smoke only in relevant contexts (e.g., places, affects, triggers). The immediate nicotine reduction group reported less smoking satisfaction and lower completion rates (72% immediate reduction versus 88% gradual reduction, p=.02). Abstinence (biochemically verified) at 2 months post study was 29%. There were no significant differences between the 4 study groups. VLNC were beneficial in smoking cessation.   Read this issue of the ASAM Weekly Subscribe to the ASAM Weekly Visit ASAM

Supplement audit and tracking apps like Subtract AI, Sepco, and other supplement ranking tools are everywhere right now — but are they actually helping your health… or giving you false confidence?   In this episode, I break down the 3 major flaws with supplement auditing apps that most people (and even doctors) overlook — especially if you're dealing with fat loss resistance, hormone imbalance, thyroid issues, HRT, or birth control.   You'll learn: • Why these apps often miss dangerous drug–supplement interactions • How they ignore your diet, nutrient intake, and deficiencies • Why they don't account for dosing, form, or timing (which completely changes how supplements work) • How they oversimplify complex hormonal health • Why your "high score" may mean absolutely nothing • When supplement apps CAN be useful vs when they become harmful • Why supplements must be personalized to your labs, diet, stress, and hormones   If you're taking a large supplement stack, using HRT or thyroid meds, or trying to lose stubborn fat — this is a MUST-listen before trusting any supplement-tracking app.

Discover the latest science behind fasting and innovative fasting alternatives in this episode with Dr. Chris Rhodes, nutritional biochemist. Learn about the anti-inflammatory and longevity benefits of a 36-hour fast, and how Mimio, a fasting supplement, can help you access fasting's advantages without skipping meals. With special insights on women's health—including hormones, muscle preservation, and metabolic changes—this is essential listening for anyone interested in optimizing wellness, especially women navigating midlife.Curious to try Mimio for yourself? Visit https://drstephanieestima.com/mimio and use code ESTIMA for 20% off. Episode Overview (timestamps are approximate):(0:00) Intro/Teaser(4:00) The Biology of Fasting: What's Actually Happening(12:00) Fasting Timelines: 16:8 vs 24hr vs 36hr(16:00) The 36-Hour Metabolic Signature(21:00) NAD, Estrogen, and Women in Midlife(26:00) Cortisol, HPA Axis, and Female Sensitivity(30:00) Thyroid Suppression During Fasting(34:00) Muscle and Bone Preservation Strategies(43:00) The Four Fasting-Mimetic Molecules(54:00) Fasting Benefits Without Fasting(1:03:00) Clinical Study Results: 2.5 Years Younger(1:07:00) Dosing and Best Practices(1:12:00) BONUS: After-Party with Dr. StephanieResources mentioned in this episode can be found at https://drstephanieestima.com/podcasts/ep445/We couldn't do it without our sponsors:BON CHARGE - Achieve glowing skin, gain more energy, and uplevel your recovery practice with a suite of red light products. Get 15% off at https://boncharge.com/better with code BETTER.TROSCRIPTIONS - There's a completely new way to optimize your health. Give it a try at https://troscriptions.com/BETTER or enter BETTER at checkout for 10% off your first order.BIOPTIMIZERS - Your digestion can take a hit in midlife, but you don't have to suffer. Learn how enzymes can help at https://bioptimizers.com/better and use code BETTER to get 10% off your order.MASA - MASA's chips contain just three ingredients: organic nixtamalized corn, sea salt, and 100% grass-fed beef tallow. That's it. Ready to give MASA (or Vandy) a try? Use code BETTER for 25% off your first order at https://masachips.com/BETTERLMNT - Rehydrate with the perfect mix of sodium, potassium, and magnesium. Get a free sample pack at https://drinklmnt.com/drestima. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Presbyopia is finally meeting its match in-clinic with Qlosi™ presbyopia eye drops (pilocarpine 0.4%), offering a practical, performance-based option alongside glasses, contact lenses, and surgery. In this episode, Dr. Jennifer Lyerly and Dr. Derek Cunningham discuss how to position presbyopia drops for success, including who to treat, how to dose, what to say chairside, and why athletes appreciate the functional freedom.

In this episode, Linda Nurra returns to discuss the practical role of flower essences and how they complement homeopathy. She explains why flower essences are accessible tools for both practitioners and home prescribers, especially when supporting emotional well-being. Linda highlights how these remedies can help homeopathy students manage common challenges such as overwhelm, insecurity, and perfectionism. She also describes how flower essences can support clients during homeopathic aggravations without interfering with remedies. Throughout the conversation, Linda emphasizes self-care, emotional intelligence, and the importance of empowering individuals with gentle, supportive tools. Episode Highlights: 05:35 - Flower essences and homeopathy as sister healing arts 07:29 - A bridge for people not yet ready for homeopathy 09:58 - Whole-person focus over diagnoses 13:30 - Flower essences extending support beyond acute care 18:12 - Ideal gift for pregnant friends or midwives 21:35 - Supportive remedies for each stage of learning 24:31 - Flower Essences for Guilt and Boundaries 27:30 - Remedy that can help students return to the present moment 30:27 - Dosing and Application of Flower Essences 40:14 - How Flower Essences Encourage Self-Reflection in Children 46:46 - Managing Remedy Aggravations with Flower Essences 47:56 - Using Rock Rose for Panic and Anxiety 50:14 - When Theory Meets Reality About my Guests: Linda Nurra, PhD, CCH, RSHom(NA), is a dedicated teacher whose work bridges homeopathy, flower essence therapy, and the deeper study of human meaning and consciousness. With a background in humanities, linguistics, and semiotics, she spent years in higher education as an instructor, curriculum designer, trainer, and leader. Her healing path began nearly three decades ago with an encounter with flower essences—a moment that opened the door to exploring human emotion, the wisdom of plants, and the transformative capacity of nature. That journey eventually expanded into studies of spiritual and healing traditions, culminating in a profound experience with a homeopathic remedy that set her on a new professional course. Linda earned her advanced practitioner diploma from the School of Homeopathy (UK) and has since trained with leading teachers around the world. Her career has focused on teaching, writing, community-building, and supporting both students and practitioners in deepening their understanding of holistic healing. She has served as curriculum director and lead faculty at the Prometheus Homeopathic Institute, taught for the Los Angeles School of Homeopathy and the Veterinary Homeopathy Institute, and contributed to multiple publications. A former board member of the California Homeopathic Medical Society, Linda also leads several study groups that foster collaboration, learning, and a vibrant sense of community within the homeopathic field. Find out more about Linda Website: https://www.insighthomeopathy.com/ Instagram: https://www.instagram.com/linda_nurra/ Facebook: https://www.facebook.com/BachforHomeopaths YouTube: https://www.youtube.com/@lindanurra/shorts If you would like to support the Homeopathy Hangout Podcast, please consider making a donation by visiting www.EugenieKruger.com and click the DONATE button at the top of the site. Every donation about $10 will receive a shout-out on a future episode. Join my Homeopathy Hangout Podcast Facebook community here: https://www.facebook.com/groups/HelloHomies Follow me on Instagram https://www.instagram.com/eugeniekrugerhomeopathy/ Here is the link to my free 30-minute Homeopathy@Home online course: https://www.youtube.com/watch?v=vqBUpxO4pZQ&t=438s Upon completion of the course - and if you live in Australia - you can join my Facebook group for free acute advice (you'll need to answer a couple of questions about the course upon request to join): www.facebook.com/groups/eughom  

Today, I am delighted to be joined by a friend and colleague, Mike Mutzel.  Mike has a master's in Clinical Nutrition from the University of Bridgeport. He is a graduate of the IFM, applies functional medicine in clinical practice, and is a consultant lecturer who teaches leading-edge science in a concise format for progressive clinicians to prevent chronic diseases.  In our discussion, Mike and I unpack the benefits of creatine monohydrate, highlighting the importance of ensuring the products we use are free of impurities. We explain how creatine monohydrate gets created, answer many listener questions, and describe current research specific to creatine monohydrate, discussing ways to support bone health, navigate dosing, and how to troubleshoot.  This conversation with Mike Mutzel is truly invaluable, and I look forward to having him back on the podcast to dive a little deeper into the science.  IN THIS EPISODE, YOU WILL LEARN: How creatine supports energy production across muscles, the brain, and other organ systems Why vegetarians and vegans should take creatine What to consider when choosing high-quality creatine supplements Dosing strategies based on diet, exercise, sleep, and individual needs How taking creatine with electrolytes while exercising can improve absorption Benefits of supplementing with amino acids alongside creatine for illness, recovery, or when protein intake is low Adjusting your creatine dosage for sleep, travel, or exercise demands How creatine supports bone and muscle health  The value of creatine for the eyes and ears Connect with Cynthia Thurlow   Follow on X, Instagram & LinkedIn Check out Cynthia's website Submit your questions to support@cynthiathurlow.com Connect with Mike Mutzel On his website YouTube Instagram High Intensity Health Podcast Creatine Research: Creatine in Women's Health: Bridging the Gap From Menstruation Through Pregnancy to Menopause Effects of Creatine and Resistance Training on Bone Health in Postmenopausal Women Creatine Supplementation (3 g/d) and Bone Health in Older Women: A 2-Year, Randomized, Placebo-Controlled Trial Creatine Supplementation in Depression: A Review of Mechanisms, Efficacy, Clinical Outcomes, and Future Directions The Effects of 8-Week Creatine Hydrochloride and Creatine Ethyl Ester Supplementation on Cognition, Clinical Outcomes, and Brain Creatine Levels in Perimenopausal and Menopausal Women (CONCRET-MENOPA): A Randomized Controlled Trial

Another powerful episode is live here on IVPN-Voice!

I'm joined today by Edmarie Guzman-Velez & Rudy Tanzi as we dig into a clinical trial of nicotinamide riboside for Long Covid, why NAD matters for cellular energy, and where the results show promise for fatigue, sleep, mood, and executive function. We share what worked, what did not, and the next steps.• Overview of NAD, mitochondria, and energy in brain and immune cells• Why Covid may deplete NAD and how NR restores it• Trial design using intra-individual crossover with placebo run-in• Dosing at 2,000 mg NR daily under IRB oversight• Serial NAD blood measurements confirming a threefold rise• Outcomes on fatigue, sleep quality, depressive symptoms, executive function• Limits of small samples and reinfection attrition• Safety, label guidance, and medical supervision for supplements• Plans for biomarkers of inflammation and activity data from wearables• Future research on symptom clusters, sex differences, and combinationsLinks:Full paper available HEREMore about Niagen Bioscience Dr. Tanzi is paid consultant for, and equity holder in Niagen Biosciences.Message the podcast! - questions will be answered on my youtube channel :) For more information about Long Covid Breathing courses & workshops, please check out LongCovidBreathing.com (music credit - Brock Hewitt, Rule of Life) Support the show~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~The Long Covid Podcast is self-produced & self funded. If you enjoy what you hear and are able to, please Buy me a coffee or purchase a mug to help cover costsTranscripts available on individual episodes herewww.LongCovidPodcast.comFacebook Instagram Twitter Facebook Creativity GroupSubscribe to mailing listI love to hear from you, via socials or LongCovidPodcast@gmail.com**Disclaimer - you should not rely on any medical information contained in this Podcast and related materials in making medical, health-related or other decisions. Please consult a doctor or other health professional**

Reality Hub Podcast – Episode 81 with Rixt Botello Low Dose Herbal Medicine, Plant Consciousness & Person-Specific Dosing In this episode we sit down with herbalist, teacher and author Rixt Botello from Rixt's Herbals to explore her lifelong journey with herbal medicine and her unique low dose / low drop dosage philosophy. Rixt shares how getting sick as a young horticulturist (bare feet, Roundup, heavy smoking and all) led her to completely change her lifestyle, clean up her body before having children, and eventually train as a medical herbalist. With around 37 years of practice behind her, she talks about why less herbal material can often do more – for people, and for the planet. We dig into the difference between low dose herbalism and homeopathy, why some traditions moved toward “heroic doses”, and what Rixt calls a “person specific dose” – tailoring the amount to the individual, their life situation, stress, environment and even ethnicity. She also explains how low dose approaches can help protect endangered plant species and save people money, without losing effectiveness. From there, the conversation opens up into the “web of life”: plant consciousness, roots and mycelium as the original internet, Emoto's water crystal experiments, and how the plants you need often literally grow right outside your window. Rixt's Book & Online Course Rixt has poured 23 years of research into her book: Low Dosage Methodology in Herbal Medicine – a story-style herbal text with case studies and academic depth woven through it. She now teaches this material in an 8-module online course, starting January 11th, where she personally interacts with students. The course is suitable for: People with a genuine interest in herbs and herbal medicine, Existing practitioners and health professionals wanting to understand low / drop dosage and dosing methodologies (posology) in more depth. The course is delivered online (via Mighty Networks) with resource materials, glossary and clear explanations so you can revisit and apply the ideas in your own context. Links from the Episode Rixt's Herbals website - https://rixtsherbals.co.nz Book – Low Dosage Methodology in Herbal Medicinehttps://rixtsherbals.co.nz/shop/rixts-books/low-dosage-methodology-in-herbal-medicine-book/Course – Low/Drop Dosage in Herbal Medicine Certificate Level 1 (Online course, 8 modules, starts January 11 – enrolments open now)https://rixtsherbals.co.nz/low-drop-dosage-in-herbal-medicine-certificate-level-1/

Donate (no account necessary) | Subscribe (account required) Join Bryan Dean Wright, former CIA Operations Officer, as he dives into today's top stories shaping America and the world. In this Monday Headline Brief of The Wright Report, Bryan examines the rising risk of war with Venezuela, secret peace talks over Ukraine, the abduction of Christian schoolchildren in Nigeria, Israel's shifting posture in Gaza and Lebanon, and the domestic political fight over sedition and extremist rhetoric inside the United States government. U.S. and Venezuela Move Closer to War: President Trump authorized covert CIA operations inside Venezuela, prompting the FAA to warn airlines about dangerous conditions in Venezuelan airspace. Reports from Bloomberg, Reuters, and the New York Times confirm GPS jamming and rising military activity. A Russian oil tanker headed for Caracas was turned away twice by the USS Stockdale and is now anchored off Cuba. Bryan notes that the White House still hopes for a peaceful exit by President Maduro, with Colombia offering asylum in exchange for guarantees of no future attempts to kill or arrest him. Trump's Ukraine Peace Plan Faces Pushback: A secret twenty-eight-point peace plan leaked last week, calling for Ukraine to give up parts of the Donbas, reduce its military to six hundred thousand troops, and abandon NATO membership. The plan would also restore economic ties between Russia and the West and release frozen Russian funds for joint rare earth projects. European leaders object, and President Zelenskyy says negotiations must continue, insisting Ukraine needs a larger standing army to deter future invasions. Bryan emphasizes that Trump wants the deal signed by Thanksgiving, warning Zelenskyy that U.S. support may end if he refuses. Ukraine's Deepening Corruption Crisis: Fifteen to thirty percent of aid intended for Ukraine's military and energy needs has been stolen, according to recent reporting. Several allies of Zelenskyy have been arrested, and the president's key aide, Andriy Yermak, is widely suspected of involvement. Ukraine's anti-corruption agency plans more indictments this week, placing Zelenskyy in a weakened negotiating position. Islamists Kidnap Christian Children in Nigeria: Three hundred Christian students were abducted from a Catholic school in central Nigeria. About fifty escaped by fleeing into the forest and hiding until farmers rescued them. Boko Haram and other jihadist factions are believed to be responsible. Bryan warns that these groups aim to build an Islamic caliphate across the Sahel and into the Gulf of Guinea, threatening regional Christians and strategic minerals such as cocoa, iron ore, bauxite, and oil. Trump has warned Nigeria that failure to protect Christians could trigger U.S. military action. Israel Reshapes Gaza and Expands Strikes in Lebanon: U.S. troops are withdrawing from Gaza's coordination center. Israeli, Arab, and vetted Palestinian officials will manage reconstruction in a new "Green Zone," while unvetted Palestinians remain in a devastated area controlled by Hamas. Polling shows Hamas' support has risen inside Gaza, meaning roughly half the population may remain under militant control. Israel also intensified operations in Lebanon, killing Hezbollah's top military commander in a drone strike despite an ongoing ceasefire. Jewish Extremists Spark Crisis in the West Bank: Prime Minister Netanyahu convened emergency meetings after Jewish extremists torched Palestinian homes and cars in a village attack. Israeli officials say about two hundred seventy young men are responsible for the most recent incidents and vow to act. Sedition Caucus Escalates Rhetoric Against Trump: Former CIA, FBI, and military officials who now serve as Democrats in Congress released a video urging service members to resist unlawful orders from President Trump. Senator Elissa Slotkin admitted she knows of no unlawful orders but says such orders might come. Bryan calls the effort a psychological operation designed to sow confusion inside the military. Legal experts warn that service members who refuse lawful orders could face court-martial and prison. Trump Meets NYC's Socialist Mayor Elect: Zohran Mamdani met with President Trump on Friday, and the two agreed on issues such as electricity costs and housing. Mamdani later repeated his belief that Trump is a fascist and a Nazi, prompting Republican leaders like Elise Stefanik to call Mamdani a jihadist with a long documented history of radical associations. Bryan argues the evidence strongly supports Stefanik's view and warns against normalizing Mamdani's ideology. Eric Swalwell Runs for Governor of California: Representative Swalwell announced his campaign on Jimmy Kimmel Live, promising to lead the "Resistance" against Trump. Bryan revisits the long-running Chinese influence operation that targeted young California Democrats, including Swalwell, and raises questions about whether the FBI ever thoroughly investigated the network linked to his former associate Fang Fang. Good News in Medicine: Japanese researchers found that the amino acid arginine significantly reduced Alzheimer's-related plaque and inflammation in animal studies. Dosing remains experimental, but Bryan notes it could offer a promising option for families exploring right-to-try pathways.   "And you shall know the truth, and the truth shall make you free." - John 8:32   Put a smile on your face and give joy to your taste buds… Give Masa and Vandy beef tallow chips a try today! Use code WRIGHT for 25% off your first order… at MASAchips.com or VandyCrisps.com. So incredibly delicious! I promise, you won't be disappointed.   Keywords: Venezuela CIA operations FAA warning, USS Stockdale Russian tanker, Maduro Colombia asylum offer, Ukraine Trump twenty eight point plan, Donbas concessions NATO ban, Zelenskyy corruption Yermak indictments, Nigeria Christian school kidnapping Boko Haram, Gaza Green Zone Hamas polling, Hezbollah commander killed Lebanon, Slotkin sedition unlawful orders video, Zohran Mamdani socialist jihadist ties, Eric Swalwell Fang Fang China influence, arginine Alzheimer's study Japan

Get a practical breakdown of Afrezza, the ultra-rapid inhaled insulin, with this comprehensive guide to efficacy, timing, and real-world application. Join Drs. Jeremy Pettus and Steve Edelman—endocrinologists living with Type 1 diabetes—as they reveal why this unique tool is often misunderstood and how to use it effectively to flatten post-meal spikes.In this episode, we move beyond the basics to correct the biggest mistake users make regarding Afrezza dosage. If you've tried this therapy before and felt it "didn't work," the issue often lies in the conversion ratio. We review data from Afrezza MannKind studies (such as INHALE-3) to explain the shift from the old 1:1 ratio to the more effective 1:3 ratio. We also cover why this "rapid-on, rapid-off" insulin is the ultimate solution for exercise and how to navigate insurance coverage and prior authorizations.Topics covered in this episode:The Dosing Fix: Why you often need a higher Afrezza dosage compared to subcutaneous insulin.Speed & Kinetics: How inhaled insulin mimics the body's natural beta cells to clear glucose fast.Lifestyle Benefits: Managing "sticky highs," exercise without crashing, and dietary freedom.Safety & Screening: Spirometry requirements and who should (and shouldn't) use Afrezza.Pediatric Updates: The latest on clinical trials and potential approval for children.Whether you are managing Type 1 or Type 2 diabetes, this episode provides the practical "tips and tricks" you need to determine if Afrezza is the missing tool in your diabetes management kitTimecodes: 0:00 Intro: Inhaled Insulin History 0:59 How Fast is Afrezza? (Rapid On/Rapid Off) 2:19 Why It Prevents "Delayed Lows" 3:24 The Big Mistake: Why Dr. Pettis Quit Using It 5:20 The Correct Dosing Conversion (1:1 vs 1:3) 7:40 Timing: Do You Need to Pre-Bolus? 8:44 "Follow-On" Dosing for High Protein/Fat Meals 10:32 Cartridge Sizes & "Bucket" Dosing 12:11 Using Inhaled Insulin for Exercise 13:58 Real-World Test: Trix Cereal & Afrezza 15:00 Storage Tips: Fridge vs. Room Temp 16:20 Dealing with the Cough Side Effect 17:05 Proper Inhalation Technique 19:13 Using Afrezza with Insulin Pumps & Closed Loops 21:30 Pediatric Update: Is it Safe for Kids? 23:25 Lung Safety, Smokers & Spirometry Tests 24:25 How to Talk to Your Doctor About Afrezza 26:32 Prescriptions & Trainers 28:44 ConclusionVisit TCOYD's Website for more diabetes edutainment for people living with diabetes: tcoyd.org**Tune in for two new episodes each month! Like what you hear and want to help us grow? Please rate and review this podcast so we can reach more people living with diabetes!**Follow our social media channels to empower yourself with the essential areas of diabetes knowledge led by two endocrinologists living with type 1 diabetes: Facebook  |  Instagram  |  YouTube ★ Support this podcast ★

Welcome back to the tasty morsels of critical care podcast. This is the second of 2 parts on PE in critical care. The first focused on risk stratification and this one will focus on management. There is a link to a transcript of a more comprehensive talk with references on emergencymedicineireland.com for those keen enough to dive a little deeper. As noted in the last podcast this one leans very heavily on “in the my experience” level of the evidence pyramid and should be weighted as such. For this discussion I’m going to assume your patient is in the ESC High risk category, ie hypotensive with a PE on imaging and you’re satisfied that the PE is causing the hypotension. I do believe there is a tiny cohort of the PE population who warrant aggressive reperfusion even with a normal appearing BP but at this stage I cannot say I have any evidence or guidance to really identify who they are and back that up. For the original talk I gave on this to an EM audience, I split the interventions into helpful , distractions, and not helpful. It was probably a little bit of a provocative division if I’m honest. The slide is on the site for reference and viewing it will likely make what follows more edifying. For the resus room patient in the first 30-60 mins I feel comfortable to standby my assertion that a short list of “helpful interventions” should includes lysis, anticoagulation, noradrenaline, oxygen and some CPR. In the ICU however we’re often present both at the first 30-60 mins but over next hours and many of the items on the “distraction” list become a little more relevant with time. Number 1 on my list of helpful interventions is thrombolysis. As mentioned, if you have found PE and you have satisfied yourself that the sickness and hypotension you’re seeing is caused by that PE then you need to have a good reason not give thrombolysis. The evidence base is not high level RCTs but it is a class 1 recommendation on the ESC guidelines and the list of class 1 interventions is really quite short. In the 25 year old in resus with a massive PE day 3 after an arthroscopy the decision here seems pretty straightforward. However in the post trauma patient in the ICU with massive PE with a small traumatic SAH and an improving SDH and a recent laparotomy then the decision is orders of magnitude more complex and you may well find a very good reason why lysis is not an option. There is not a straightforward answer to lysis because it will vary from patient to patient but I would emphasis that it is a question worth dedicating a decent chunk of your cognitive bandwidth to. Dosing in an unstable patient is often 10mg of alteplase followed by 90mg over 2 hrs. Dosing in a cardiac arrest situation is typically a 50mg bolus. Anticoagulation is one of the other class 1 recommendations on the ESC list. Opinions vary on agent of choice. With my ICU hat on I will almost always advocate for UFH as I feel confident that if i stop it, the heparin effect will be gone in a couple of hours when the inevitable bleeding starts. Opinions vary and I know smart people who advocate for LMWH in this scenario with one of the arguments being you probably get more reliable and quicker anti Xa effect. Both the guidelines and your esteemed narrator recommend against volume resuscitation. Dumping a litre of crystalloid into the venous circulation will shift the IVS further towards the left impairing cardiac filling and doing the opposite of what you intended. A much better resuscitation fluid would be noradrenaline. This is remarkably effective in improving BP and perfusion and I have often used it when I am 90% sure the patient has a PE but haven’t quite got the CT scan to prove it. The noradrenaline can also buy you a little time to make a better decision about the lysis and reperfusion, converting what would have been an immediate decision into something that you maybe have more like 30 mins to make. Certainly if the noradrenaline dosage is rising and the right heart is struggling then adrenaline would be my add on inotrope of choice. Of course we know in the ICU we have a plethora of other agents available to us with lots of theoretical advantage on pulmonary vascular resistance etc. They would rarely be my first line, certainly not in the ED population but I would often reach for them a little further down the line once i have a better handle on the physiology and what they might tolerate. Enough to say that staring someone on 0.5mcg/kg/min milrinone as a single agent with a starting BP of 60/40 is not likely to end well in this context Oxygenation is strongly endorsed given its proclivity for reduction in PVR, however intubating someone in this context to facilitate oxygenation is likely to result in a catastrophic haemodynamic collapse. The adage “resuscitate before you intubate” or even “reperfuse before you intubate” has some relevance here. I find CPR to be helpful in the context of massive PE, not simply for the usual reasons of preserving some degree of forward flow but I suspect there is a mechanical effect of breaking up or moving clot more distally. I have frequently seen stuttering intermittent ROSC in this context. I would suggest caution with the mechanical CPR devices as the presence of a liver lac in the context of tPA is unlikely to be well tolerated. While not available or that relevant to the emergency medicine population I do think the addition of nitric in the ventilated ICU patient who develops nasty PE seems like a low risk intervention with potentially massive gains. There is a small RCT of nitric in the spontaneous breathing PE population that did not however show benefit. I put mechanical devices in the “distraction” category in my original talk as I don’t think they have much relevance in the early stage of resuscitation. However if you have kept them alive long enough or if you have a true contraindication to lysis or a failed lysis then they may well have a role. I have found the evidence base so far here decidedly underwhelming and for catheter directed lysis in particular i struggle to see how a mg/hr tpa via a pulmonary catheter is any different than a mg/hr of tpa via a peripheral IV line given that the entire venous return ends up in the pulmonary circulation either way. The thrombectomy devices are certainly more compelling from a physiological perspective and the obvious and dramatic changes in physiology on removal of clot are quite compelling. But they are a tremendous faff requiring a catheter akin to an ECMO catheter to be threaded into the pulmonary circulation. The recent PEERLESS trial gave an average 90 min procedure time emphasizing the need to keep the patient alive long enough to receive the intervention. I do feel this has a role in our management quiver I am just unsure what that role is, but more evidence in the coming years will likely clarify VA ECMO is undoubtedly a fantastic physiological support for a dying PE patient but bear in mind it is almost definitely not available to you in the vast majority of hospitals in the Ireland and the UK. PERT teams are groups of relevant physicians willing to weigh in on difficult PE cases to advise on management. I put PERT teams in the distraction category. And I feel bad about that because they're usually filled with knowledgeable and enthusiastic people . But there are 2 errors I've seen on this that we should be aware of. One is on us as primary clinicians where we outsource the decision to lyse in someone who has a clear indication. This is not necessarily the fault of the PERT team but there is risk to the patient in delaying as it is a tremendous faff trying to get hold of the relevant people and then get them to agree. The second distraction that can happen is the recommendation for interventions in a patient that they have not seen and are not present to. A couple of times I have had to talk people out of IR interventions that frankly were not needed because the patient was getting better with conventional treatment. Do not underestimate the importance of being at the bedside and seeing the patient and evaluating response to treatment. Surgery, in terms of pulmonary embolectomy is the third and final class 1 recommendation in the ESC guidelines for high risk PE. All be it with a very low evidence rating. It gets talked about in papers and guidelines but you're talking about taking someone who is already mostly dead into theatre, lined, anaesthetised, chest opened and onto bypass. There probably is a role for it somewhere and in certain institutions and it's often raised in the context of contraindications to lysis but those same contraindications to lysis usually apply to the 30000 units of heparin you need to get them on bypass. It seems to suffer from the old goldilocks flaw of “not sick enough” for theatre or “too sick” for theatre I have clearly done way beyond my usual brevity in this scenario but honestly didn’t think anyone could tolerate a 3rd part on PE. Full refunds are available on request For further reading it is probably best to visit the original lecture post where the relevant papers are all listed with a little smattering of critical appraisal thrown in for good measure.

In this months Q&A episode I answer listener questions including: What are my thoughts on B vitamins? Should we supplement them or get them from food? What is one thing the anti PUFA crowd gets wrong? What are my thoughts on testing omega 3:6 ratio from a dried blood spot sample? What do I think about Dr Matthew Walker on Diary of a CEO Podcast saying "don't supplement large doses of melatonin"? What is a good dose of melatonin for kids? Have I ever taken melatonin to lower anxiety? What do I think about red light and PEMF mats? What is my parasite strategy? What belief or mindset shift created the biggest change in my health? I share why I think vitamin B3 as niacinamide/nicotinamide is one of the most important ones to take, how B3 protects against several different types of cancers, why cigars don't protect from pathogens in oysters, the immense stress lowering effect I felt when I stopped demonizing ascorbic acid, zinc, iron, and vitamin D supplements, and why I think the should observe the diets of deer and elk with the PUFA conversation instead of getting lost in analyzing endless research studies.  My website: www.matt-blackburn.com Mitolife products: www.mitolife.co BLACK FRIDAY SALE STARTS MONDAY 11/24 Some of the studies cited in the show:  NIacinamide skin cancer study https://pmc.ncbi.nlm.nih.gov/articles/PMC4570055/ Niacinamide non hodgkin lymphoma study https://pubmed.ncbi.nlm.nih.gov/37467318/ PUFAs as Anti-Freeze article: https://www.anbg.gov.au/cryptogams/underworld/panel-13/index.html Music by George Henner: https://georgehenner.bandcamp.com

Methylene blue is one of the most misunderstood compounds in biohacking, yet it can upgrade your energy, mood, memory, and cellular resilience when you use it the right way. We are back again with another solo masterclass, and this one breaks down how to use methylene blue as a precision tool for brain optimization, longevity, and human performance while avoiding the dosing mistakes that create jitteriness, sleep disruption, or dangerous interactions. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey guides you through more than a century of research on methylene blue. He has been hacking this compound since the early 2000s and brings deep insight into mitochondria, neuroplasticity, metabolism, supplements, fasting, red light, ketosis, nootropics, and functional medicine. You will learn how methylene blue works inside the cell, how it improves electron transport, and why it appears in neurology, psychiatry, and anti aging research at the same time. This episode shows you how to test your own dose, how to stack it with light and ketosis for maximum effect, and how to avoid serotonin syndrome or sleep disruption. Methylene blue also touches nearly every major system that biohackers care about, which is why this solo masterclass shows you how it interacts with mitochondria, neuroplasticity, metabolism, sleep optimization, and long term anti aging pathways. You will hear how it influences redox balance, ATP production, brain optimization, and stress resilience, and how it behaves when combined with ketosis, fasting, creatine, NAD boosters, red light therapy, or other nootropics. Host Dave Asprey explains why methylene blue pairs well with certain supplements but clashes with psychedelics or SSRI medications, how it fits into functional medicine protocols for mitochondrial repair, and how to use data and wearable tracking to dial in your response. This episode gives you a complete framework to evaluate whether methylene blue belongs in your personal longevity strategy and how to use it with precision instead of guesswork. You'll Learn: • Why methylene blue acts like mitochondrial jumper cables and when it improves energy and mood • The exact signs that your dose is too strong, too weak, or in the Goldilocks zone • How methylene blue interacts with neuroplasticity, memory circuits, and cognitive resilience • Why psychedelics, SSRIs, and MAO inhibitors can create dangerous serotonin interactions • How to pair methylene blue with red light therapy, ketosis, creatine, fasting, or NAD boosters • The link between mitochondrial health, fertility, libido, and long term anti aging strategies • How to track sleep optimization, HRV, and performance signals to dial in your personal protocol • The difference between aquarium grade dye and pharmaceutical grade formulations • Why genetic testing for G6PD deficiency is essential before higher dose experimentation Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: methylene blue dosing, mitochondrial electron transport, Complex IV cytochrome c oxidase, redox cycling, MAO inhibition, serotonin syndrome risk, G6PD deficiency caution, neuroplasticity enhancement, dendritic spine density, mitochondrial stress adaptation, red light therapy stacking, cognitive performance optimization, ketone supported ATP production, nitric oxide independent focus boost, mitochondrial bottleneck repair, pharmaceutical grade methylene blue, sleep disruption signals, biohacking fertility support, oxidative stress buffering, functional medicine mitochondria repair Thank you to our sponsors! -BrainTap | Go to http://braintap.com/dave to get $100 off the BrainTap Power Bundle. -fatty15 | Go to https://fatty15.com/dave and save an extra $15 when you subscribe with code DAVE. -Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order. Resources: • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Trailer 1:25 — Introduction 4:51 — History of methylene blue 7:38 — How methylene blue works 14:05 — Safety 17:53 — Dosing and timing guidelines 20:41 — Combining with red light therapy 22:41 — Quality and sourcing 23:17 — Dosing protocols 25:24 — Longevity and fertility effects 29:24 — Stacking options 32:10 — Common questions and FAQs 33:40 — Future research and wrap up See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Glycopyrrolate is an anticholinergic medication commonly used to reduce excessive secretions, particularly in palliative care, postoperative settings, and certain neurologic conditions. It works by blocking acetylcholine at muscarinic receptors, which decreases salivary and respiratory secretions. Clinically, glycopyrrolate is often used to manage terminal respiratory secretions (“death rattle”). Adverse effects of glycopyrrolate are primarily related to its anticholinergic properties. These may include dry mouth, constipation, urinary retention, blurred vision, tachycardia, and decreased sweating. While it has fewer central effects than agents like scopolamine, caution is still warranted in patients with glaucoma, gastrointestinal obstruction, or significant urinary retention risk. Monitoring hydration and bowel function is important, especially in elderly or frail patients. Dosing strategies depend on the clinical need. In palliative care, low doses may be given subcutaneously or intravenously every 4–6 hours as needed, while oral dosing is common for chronic sialorrhea. Clinicians should consider the patient's overall medication burden, as cumulative anticholinergic load can worsen cognitive impairment and contribute to falls or constipation. I discuss drug interactions and other commonly used medications that may contribute to anticholinergic burden.

Pre-Order The Forever Strong PLAYBOOK and receive exclusive bonuses: https://drgabriellelyon.com/playbook/Want ad-free episodes, exclusives and access to community Q&As? Subscribe to Forever Strong Insider: https://foreverstrong.supercast.comIn this compilation episode, Dr. Gabrielle Lyon is joined by the top experts in Testosterone and men's health treatments. You'll learn:Why aging alone doesn't drop T levels and why acquisition of conditions like obesity is the real culprit.Why the standard "low T" cutoff is misleading and why you must check your Free Testosterone.How erectile dysfunction is a sensitive marker of overall health and heart risk.The efficacy of Cialis/Viagra for both erections and cardiac protection, and the risks of unchecked influencer advice on steroids.The direct link between muscle mass, exercise, and sexual function—and why the penis is the "first to go" when overall health declines.Chapter Markers:0:00 - Testosterone is a Brain Hormone0:40 - Debunking the Myth: Male Menopause (Andropause) Doesn't Exist1:33 - The Dangers of Unchecked Influencer Advice on Testosterone3:07 - Defining Testosterone Deficiency: Symptoms vs. Signs5:10 - The Arbitrary Number: Why Guidelines Disagree on Low T8:29 - Free Testosterone: The Most Reliable Indicator of Male Health15:28 - TRT vs. Steroids: Defining the Line and Risks18:59 - The Real Risks of TRT: Infertility and Hematocrit22:36 - The Shocking Backstory: Challenging the Prostate Cancer Myth26:40 - Erectile Dysfunction (ED) and Lifestyle Modification29:21 - Shockwave Therapy for ED: The Science and the Cash Business33:53 - Penile Tissue Atrophy and Venous Leak37:25 - The Role of Muscle Mass, Sarcopenia, and Sexual Function39:41 - The Single Best Marker for Male Health: Erectile Function42:02 - The Science of Cialis and Viagra (PDE5 Inhibitors)45:49 - The Viagra Story: From Heart Drug to ED Cure50:50 - Tadalafil (Cialis) as a Triple-Threat Drug (Cardiac, Urinary, Sexual)53:57 - The Role of Testosterone in Female Sexual Function55:20 - Hypogonadism: Diagnosis, Treatment, and Fertility RiskAbout the guests: Dr. Abraham Morgentaler is an Associate Clinical Professor of Urology at Harvard Medical School and founder of Men's Health Boston. He is an internationally recognized expert in men's health, particularly known for his pioneering work in testosterone therapy. Dr. Morgentaler is credited with reversing the long-held belief that testosterone therapy causes prostate cancer and is the author of several books on men's health. YouTubeLinkedInT4L EducationX/Twitter Dr. Tobias Kohler is the co-founder of the Erectile Restoration Outcomes Study (EROS) penile implant registry. In addition to his clinical and research activities, Dr. Kohler is active in education, providing mentorship to residents and fellows.Mayo Clinic ResearchGateLinkedIn

Welcome back to Don't Miss a Beat! In this episode of Don't Miss a Beat, cohosts Steven Green, MD, and Muthu Vaduganathan, MD, MPH, sit down with Ambarish Pandey, MD, from UT Southwestern, to discuss the landmark POLY-HF trial, presented at the 2025 American Heart Association Scientific Sessions in New Orleans. The discussion centers on the novel concept of a “polypill” approach for patients with heart failure with reduced ejection fraction (HFrEF), aiming to simplify guideline-directed medical therapy (GDMT) and improve adherence while maintaining safety and efficacy. Key Timestamps 00:00:00 Introduction 00:00:45 Polypills in cardiovascular medicine 00:02:32 Structuring the POLY-HF trial 00:05:00 Mechanics of POLY-HF 00:07:43 The patient population in POLY-HF 00:09:47 Dosing other medications in POLY-HF 00:11:54 Results of POLY-HF 00:14:57 Reaching endpoints in POLY-HF 00:18:52 Safety in POLY-HF 00:22:09 Upcoming studies 00:23:54 Outro 

Join Dr Sofia Ramiro and Professor Xenofon Baraliakos as they discuss the top publications in the world of axSpA. This month, the conversation covered the Association between adalimumab dosing interval and uveitis recurrence in patients with ankylosing spondylitis.

In this conversation, Dr. Nathan Bryan discusses the critical role of nitric oxide in human health, its production, and the factors that can lead to its deficiency. He explains how nitric oxide functions as a signaling molecule, its importance in cardiovascular health, athletic performance, and immune function, and the misconceptions surrounding nitric oxide supplements. The discussion also covers the impact of diet, oral hygiene, and lifestyle choices on nitric oxide levels, as well as practical biohacks to enhance its production. Dr. Bryan emphasizes the need for restorative physiology in health management and the potential of nitric oxide in future medical therapies.Dr. Nathan S. Bryan is a revolutionary scientist, biotech entrepreneur, and industry disruptor who is redefining the way we think about health, longevity, and human performance. With over 100 peer-reviewed publications and dozens of patents, his groundbreaking discoveries in nitric oxide research have shattered conventional health myths, igniting a billion-dollar market and transforming countless lives. A former professor of molecular medicine, Dr. Bryan left academia to take on Big Pharma and misinformation head-on, delivering real, science-backed solutions directly to the public. Now, as a sought-after speaker and author of The Secret of Nitric Oxide: Bringing the Science to Life, he's on a relentless mission to arm people with the tools to reclaim their health, optimize performance, and defy aging.SHOW NOTES:0:39 Welcome to the podcast!1:48 Dr. Nathan Bryan's Bio2:29 Welcome him to the show!3:30 The purpose of Nitric Oxide in the human body5:11 What depletes our Nitric Oxide?8:27 Erectile dysfunction & Viagra13:12 Can NO override bad habits?14:41 Nitrate-rich foods17:06 Oral microbiome & blood pressure19:29 How nitric oxide affects sleep apnea & sleep-disordered breathing 21:52 Breathing while exercising23:41 Supporting the immune system with NO25:42 Testing levels with saliva strips28:36 Dosing nitric oxide31:08 Arginine & Citrulline supplements37:36 Pharmaceutical industry45:25 Heavy metals & adrenal tumors48:39 Dr. Nathan's morning routine53:19 Where to find him54:32 Thanks for tuning in!RESOURCES:Website: drnathansbryan.comN1O1 SupplementsIG: @drnathansbryanYouTubeSupport this podcast at — https://redcircle.com/biohacker-babes-podcast/donationsAdvertising Inquiries: https://redcircle.com/brands

The JournalFeed podcast for the week of Nov 3-7, 2025.These are summaries from just 2 of the 5 articles we cover every week! For access to more, please visit JournalFeed.org for details about becoming a member.Wednesday's Spoon Feed:The Safeback SBX device can improve survival in an avalanche, but does not replace the need for appropriate education and knowledge regarding avalanche safety.Friday's Spoon Feed:For anaphylaxis in adults ≥50kg, 0.5mg vs. 0.3mg IM epinephrine is strongly associated with a reduction in escalation of care (repeat epi, epi drip, or intubation).

What if you could know—before you ever give a pill—whether your dog or cat is likely to have a bad reaction? In this episode, Dr. Alice and Janet sit down with Dr. Katrina Mealey, Associate Dean for Research at Washington State University's College of Veterinary Medicine, NIH-funded researcher, and Inventor of the Year for her groundbreaking genetic test that flags pets at risk for serious adverse drug reactions.Dr. Mealey explains the science in plain English: a natural “gatekeeper” protein called P-glycoprotein (coded by the MDR1 gene) protects the brain and body by pumping out potentially toxic compounds. When a pet carries certain MDR1 mutations, many common medications—prescription and OTC—can reach dangerous levels. We cover how the cheek-swab test works, how to get it for your pet, which breeds are most affected, why dosage matters so much, and how new vet-friendly tools help tailor safer treatments.In this episode:- MDR1 101: What P-glycoprotein does and why it's the body's drug “gatekeeper.”- Who's at risk: Collies (~75%), Australian & English Shepherds (~50%), plus surprises like Boxers, Huskies, and even the occasional Golden—plus the feline version discovered in 2015.- Real-world reactions: From anti-diarrheals and chemo agents to certain flea preventives—how problems present and what vets should watch for.- Testing made easy: Simple cheek swab or blood test; results emailed to you and your vet.- Dosing guidance: Meet MDR1Caddie (dogs) and WhisPurr (cats)—information that suggests dose adjustments based on whether a pet has one or two copies of the mutation.- Myth-busting ivermectin: Why tiny monthly heartworm doses are different from mange/cancer “DIY” dosing—and why self-medicating is dangerous.- Take-home for pet parents: Bring MDR1 status up with your vet before surgeries, chemo, dermatology meds, new preventives, or simple OTC medications like Immodium.About our guestDr. Katrina Mealey is a veterinarian, pharmacist, researcher, and author (editor of Pharmacotherapeutics for Veterinary Dispensing). Her lab identified the MDR1 mutation in dogs and later in cats, and continues to map which drugs interact with P-glycoprotein so veterinarians can treat more safely.https://vetmed.wsu.edu/our-team/wsu-profile/kmealey/Resources & links- MDR1 genetic test: Link in show notes to order a cheek-swab kit for dogs or cats.- Drug interaction updates: Ongoing lists and guidance are available via the testing program (see show notes).- Dose-adjustment information: MDR1Caddie (dogs) and WhisPurr(cats).- Talk to your veterinarian before starting, stopping, or changing any medication.--What started during the COVID-19 lockdown with one baby gorilla at the Cleveland Zoo has grown into a channel loved by animal fans around the world. I'm a one-person operation—filming, editing, narrating, and sharing the most heartfelt moments of baby gorillas, orangutans, elephants, and other zoo animals. Whether it's Jameela's emotional journey or Clementine's first steps, each video brings you closer to the animals and their stories. If you love watching real animal behavior, learning fun facts, and supporting conservation through storytelling—this is your place! Subscribe to Larry's Animal Safari on YouTube @larrysanimalsafari ---Support our sponsor for this episode Blue Buffalo by visiting bluebuffalo.com. BLUE Natural Veterinary Diet formulas offer the natural alternative in nutritional therapy. At Blue Buffalo, we have an in-house Research & Development (R&D) team with over 300 years' experience in well-pet and veterinary therapeutic diets, over 600 scientific publications, and over 50 U.S. patents. At Blue Buffalo, we have an in-house Research & Development (R&D) team with over 300 years' experience in well-pet and veterinary therapeutic diets, over 600 scientific publications, and over 50 U.S. patents.---All footage is owned by SLA Video Productions.

Testosterone therapy can improve libido in postmenopausal women.Sexual dysfunction in women is complex and multifactorial.Low sexual desire is only considered a disorder if it causes distress.Psychosocial factors play a significant role in sexual health.Testosterone levels do not change significantly at menopause.The placebo effect can significantly influence treatment outcomes.Individualized care is crucial in managing sexual dysfunction.Dosing for testosterone therapy should be carefully monitored.Current medications for low libido have modest benefits.Evidence for testosterone therapy in premenopausal women is still emerging.Tap to Follow Dr.Susan Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

In this episode, Dr. Abbie Smith-Ryan, a leading researcher in exercise science and women's health, breaks down the science behind creatine and its many benefits for women. From reducing inflammation and improving recovery to boosting brain health, mood, and sleep, Dr. Smith-Ryan shares the latest research and practical advice on how women can safely and effectively use creatine. She also addresses common myths and side effects, the best dosing strategies, and how creatine can support everything from menstrual health to perimenopause.→ Leave Us A Voice Message! Topics Discussed: → What are the benefits of creatine for women?→ Does creatine help with perimenopause and hormones?→ How does creatine support brain health and mood?→ Can women build muscle and bone mass with creatine?→ Is creatine safe for postpartum recovery?Sponsored By: → Be Well By Kelly Protein Powder & Essentials | Get $10 off your order with PODCAST10 at https://bewellbykelly.com.→ AG1 | Head to https://drinkag1.com/bewell to get a FREE Welcome Kit with the flavor of your choice that includes a 30 day supply of AGZ and a FREE frother. → Function | Learn more and join using my link. Function is the new essential health check, and my first 1000 listeners get a $100 credit toward their membership. Visit https://www.functionhealth.com/bewellbykelly or use gift code BEWELL100 at sign up to own your health.→ Vuori | Get 20% off your first order of Vuori AND free shipping on orders over $75 at https://vuori.com/kellyTimestamps: → 00:00:00 - Introduction→ 00:02:48 - Creatine for inflammation & recovery→ 00:07:05 - Other uses of creatine→ 00:12:59 - Creatine & menstruation→ 00:16:46 - PCOS & irregular cycles→ 00:17:44 - Creatine side effects→ 00:20:55 - Dosing & loading phase→ 00:26:13 - Perimenopause study insights → 00:33:11 - Brain health, mood & sleep→ 00:36:09 - Cognition & hormones→ 00:38:27 - When & how to take creatine→ 00:41:10 - Combating the afternoon crash→ 00:44:15 - Body composition explained→ 00:46:21 - Best workout times→ 00:48:49 - Fasted exercise pros & cons→ 00:52:14 - Improving bone & muscle mass→ 00:56:49 - Heavy lifting & proper form→ 00:58:04 - Surgery & injury considerations→ 00:59:07 - Lifelong athletic training→ 01:02:40 - Postpartum recovery tips→ 01:06:11 - Blood sugar balance→ 01:09:10 - Water weight & puffiness→ 01:10:54 - Types of creatineCheck Out Abbie:→ IG: @asmithryan→ WebsiteCheck Out Kelly:→ Instagram→ YouTube→ Facebook

In this week's BeBattleReady podcast, Simon Ward welcomes back Dr Tommy Wood to explore one of the most researched yet misunderstood supplements - creatine. While most athletes associate it with muscle strength, Tommy explains why its benefits go far beyond the gym, extending to brain health, cognitive function, and ageing well. Together, they unpack how creatine works, who should consider supplementing, the differences between athletic and cognitive benefits, and why it might be particularly valuable for older athletes and post-menopausal women.   Key Points Discussed: Creatine as a brain protector: Originally known for supporting strength and power, creatine also acts as an energy buffer for the brain, helping maintain cellular energy after head trauma and possibly reducing cognitive decline. Who benefits most: While everyone can gain from adequate creatine levels, the strongest evidence shows benefits for older adults, athletes at risk of head injury, and women in peri- and post-menopause — particularly for memory and bone health. Dosing, loading, and myths: You don't need the old “loading phase.” Regular small doses (3–5 g daily) are safe and effective. The minor weight gain some notice is simply better muscle hydration, not “bloating.” Sleep, mood, and cognition: Studies show creatine can offset mental fatigue and cognitive decline during sleep deprivation, and even support mood when used alongside standard therapy for depression. Safety and practical takeaways: Creatine monohydrate (especially the Creapure® form) remains the gold standard. It's safe for most people, though those with kidney issues should consult their doctor. Foods like sardines, herring, mackerel, and red meat also provide natural sources.   Key Quotation: “Creatine is probably one of the most studied supplements in the world — and on balance, it's safe, effective, and beneficial for both the body and the brain.” — Dr Tommy Wood   Connect with Dr. Tommy Wood: Website: drtommywood.com Instagram: DrTommyWood Substack: Better Brain Fitness Podcast: Better Brain Fitness Podcast   Dr. Tommy Wood's Book (Pre-order now): The Stimulated Mind: Future-Proof Your Brain from Dementia and Stay Sharp at Any Age (Release: March 24, 2026)   Book Recommendations: Attention Span by Gloria Mark - how to find focus for a fulfilling life. The Comfort Crisis by Michael Easter - embrace discomfort to reclaim your wild, happy, healthy self.     Join the SWAT Inner Circle   The SWAT Inner Circle is now open. It is the community for athletes and adventurers over 50 who want to train smart, live well, and extend their health span.  You can join today CLICK HERE TO START YOUR MISSION   Check out my Instagram  and YouTube  channel   Join the Unstuck Collective – for Beth's weekly inspiration and coaching insights (not a chat group; replies welcome via DM). Download Simon's Free ‘Battle Ready Lifestyle' Infographic — https://simon-ward.kit.com/battlereadylifestyle Website: www.simonward.co.uk Email: Simon@thetriathloncoach.com Sign up for Simon's weekly newsletter Sign up for Beth's weekly newsletter  

In this insightful conversation, Luke Gunderson and Stephanie Zimmerman share how pharmacy owners can use the 80/20 rule to simplify patient care, reclaim their time, and grow profits — without burning out. Drawing from real pharmacy experiences, they reveal how focusing on the vital 20% of patients and opportunities delivers 80% of the results. Luke and Stephanie discuss how flexible dosing becomes a practical tool in that strategy — improving adherence, creating better outcomes, and turning patient care into a powerful profit lever.   **Show Notes:** 1. **Introduction** [0:00] 2. **Introduction of Guests and Initial Questions** [4:00] 3. **Overview of Real Value RX** [8:01] 4. **Explanation of Flexible Dosing* [9:47] 5. **Addressing Concerns About Audits and Rebates** [13:06] 6. **Strategies for Implementing Flexible Dosing** [23:07] 7. **Practical Examples and Next Steps** [29:21] 8. **Conclusion and Final Remarks** [34:19]     ----- #### **Becoming a Badass Pharmacy Owner Podcast is a Proud to be Apart of the Pharmacy Podcast Network**  

For this week's episode of the Clinician's Corner, we've gone into the archives to pull out another clinical pearl from one of our favorite episodes - and today we discuss glutathione's role in detox, inflammation, and client care with Dr. Gina Nick. This interview first aired in 2024, and the full interview can be viewed here. Clinical pearls we extracted from the original interview: Dr. Gina's personal health journey and observations of people benefiting from detox Her discovery and clinical use of glutathione (including its use during Covid and with drug addiction) The science and mechanisms of glutathione (e.g., glutathione as "master antioxidant") Dosing and timing considerations Practical uses in everyday scenarios The Clinician's Corner is brought to you by the Institute of Restorative Health. Follow us: https://www.instagram.com/instituteofrestorativehealth/ Connect with Dr. Gina Nick: Website: www.bestdailyever.com Instagram: @bestdailyever and @drginanick Facebook: bestdailyever and drginahealing Twitter: @bestdailyever and @drginanick Timestamps: 00:00 "Glutathione: Master Antioxidant Insights" 05:56 "Mitochondrial Toxins and Cognitive Decline" 09:41 Gastrointestinal Healing Self-Study Launch 11:27 "Begin Your Restorative Health Journey" Speaker bio: Dr. Gina Nick is a world-renowned Naturopathic Physician, Researcher, and Formulator based in Newport Beach, California. With a dedication to holistic wellness, she's known for her expertise in treating a wide range of health concerns, from autoimmune diseases to addiction recovery, anxiety, and more. After graduation from medical school, she became the Director of Research for a leading supplement company, earning the company billions. She's since held the roles of Executive Healthcare Consultant to Local and Government Agencies and President Emeritus of the California Naturopathic Doctors Association. As the Founder and Director of Healthbridge in Newport Beach, California, her practice was awarded "Top Medical Practice 2017," a testament to her commitment to excellence. As a published author, entrepreneur, and certified yoga instructor, Dr. Gina is a multifaceted professional with a passion for improving the lives of others. With her unwavering commitment to nurturing health naturally, she's not just your typical medical professional. Dr. Gina is a nurturing soul, a devoted mom, and an advocate for holistic well-being. She's licensed in both California and Hawaii and is excited to share her journey with you. Disclaimer: The views expressed in the IRH Clinician's Corner series are those of the individual speakers and interviewees, and do not necessarily reflect the views of the Institute of Restorative Health, LLC. The Institute of Restorative Health, LLC does not specifically endorse or approve of any of the information or opinions expressed in the IRH Clinician's Corner series. The information and opinions expressed in the IRH Clinician's Corner series are for educational purposes only and should not be construed as medical advice. If you have any medical concerns, please consult with a qualified healthcare professional. The Institute of Restorative Health, LLC is not liable for any damages or injuries that may result from the use of the information or opinions expressed in the IRH Clinician's Corner series. By viewing or listening to this information, you agree to hold the Institute of Restorative Health, LLC harmless from any and all claims, demands, and causes of action arising out of or in connection with your participation. Thank you for your understanding.

In this episode, Sam Ashoo, MD and T.R. Eckler, MD discuss the October 2025 Emergency Medicine Practice article, Emergency Department Evaluation and Management of Patients With Adrenal InsufficiencyIntroduction Welcome and host introductions Brief overview of the episode's topic Resources and CME reminderArticle Overview Source: Emergency Medicine Practice, October 2025 Authors: The Simcoes Importance of evidence-based reviewClinical Context & Epidemiology Frequency and rarity of adrenal insufficiency Diagnostic challenges and statistics Importance of recognizing adrenal crisisPathophysiology Primary, secondary, and tertiary adrenal insufficiency Causes and mechanisms Key anatomical and physiological conceptsDifferential Diagnosis Overlap with other diseases (infections, autoimmune, endocrine, psychiatric, cardiac, GI, etc.) Importance of considering adrenal crisis in complex casesPrehospital Care EMS recognition and limitations Importance of medication history and emergency kits Legal and logistical barriers to prehospital hydrocortisoneEmergency Department Evaluation Recognizing symptoms and prioritizing care Role of EMR and clinical decision support Key history and risk factors (medications, steroid use, opioid use, comorbidities)Physical Examination Specific and nonspecific findings Cushingoid features vs. primary adrenal insufficiency signsDiagnostic Workup Laboratory studies (cortisol, ACTH, renin, aldosterone, TSH, etc.) Imaging considerations Gold standard tests and their limitations in the EDTreatment Immediate administration of hydrocortisone Dosing for adults and pediatrics Supportive care (fluids, glucose, treating underlying cause) Sick day dosing and home managementSpecial Populations Pregnancy considerations Septic shock and adrenal crisisCommon Pitfalls & Takeaways Delaying steroids for labs/diagnosis Importance of high suspicion and early treatment Key trivia and learning pointsClosingSummary and final thoughts Reminders for further reading and CME Farewell and next episode teaserEmergency Medicine Residents, get your free subscription by writing resident@ebmedicine.net

Review the indications, dosing, & administration of Adenosine for patients in supraventricular tachycardia (SVT) following ACLS's Tachycardia algorithm.Adenosine is the first IV medication given to stable patients with sustained supraventricular tachycardia (SVT) refractory to vagal maneuvers.Symptoms indicating a stable vs unstable patient.Common causes of tachycardia.Cardiac effects of Adenosine.Indications for use in the ACLS Tachycardia algorithm.Considerations and contraindications.Adenosine as a diagnostic for patients in A-Fib or A-Flutter with RVR.Dosing and administration.Other podcasts that cover common ACLS antiarrhythmics in more detail and another covering Brugata Criteria used to differentiate V-Tach from SVT with an aberrancy, can be found on the Pod Resources page at passacls.com.**American Cancer Society (ACS) Fundraiser This is the seventh year that I'm participating in Men Wear Pink to increase breast cancer awareness and raise money for the American Cancer Society's life-saving mission.I hope you'll consider contributing.Every donation makes a difference in the fight against breast cancer! Paul Taylor's ACS Fundraiser Page: http://main.acsevents.org/goto/paultaylorTHANK YOU for your support! Good luck with your ACLS class!Links: Buy Me a Coffee at https://buymeacoffee.com/paultaylor Free Prescription Discount Card - Get your free drug discount card to save money on prescription medications for you and your pets: https://safemeds.vip/savePass ACLS Web Site - Other ACLS-related resources: https://passacls.com@Pass-ACLS-Podcast on LinkedIn

Join our free community, The Women's Peptide Collective, click the Skool link to become a member and to connect, learn, and collaborate. https://www.skool.com/womens-peptide-collective-9663Go to https://thepeptique.com/ to get all your research peptides .As a loyal listener use the discount code POD15 to get 15% off the entire line of products.Have questions? Feel free to reach out to me: tarawest@westwellnessatx.comWant the free peptide guide? Email me tarawest@westwellnessatx.com and comment Guide and I'll shoot it right over!Follow me on instagram AND TikTOk @westwellnessatxTakeaways: The podcast discusses the complexities involved in peptide dosing, emphasizing the necessity of individualized approaches. Listeners are encouraged to perform their own research and consult professionals before initiating peptide protocols. The importance of starting peptide dosages low and adjusting gradually is highlighted to ensure safety and efficacy. Peptide experiences can vary significantly among individuals, underscoring that what works for one may not work for another. The speaker shares personal anecdotes regarding peptide effects and emphasizes the need for personalized experimentation in dosing protocols. The podcast also addresses the significance of patient-practitioner relationships in managing peptide therapies effectively.

Nicotine isn't just addictive—it might be one of the most misunderstood nootropics in modern medicine. In this masterclass, you'll learn how controlled, low-dose nicotine may enhance brain performance, boost neuroplasticity, improve mitochondrial function, and potentially extend lifespan. Host Dave Asprey breaks down the surprising science behind this controversial compound, separating fact from fear—and exposing the real risks that nobody talks about. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR You'll discover how nicotine affects neurotransmitters, why it may help with ADHD and focus, and how it compares to other cognitive enhancers like caffeine, nootropics, and even smart drugs. Dave explores how nicotine can be used to hack metabolism, enhance sleep optimization, and support fasting or ketosis protocols—if used properly. He also reveals the forms of nicotine that are safest (spoiler: it's not vapes or cigarettes), how nicotine works at the receptor level, and what the science says about long-term health effects. This episode blends functional medicine, brain optimization, and biohacking into one powerful, myth-busting breakdown. You'll Learn: • How nicotine affects mitochondria, neurotransmitters, and dopamine signaling • Why nicotine may boost neuroplasticity, memory, and attention span • How low-dose nicotine compares to caffeine, modafinil, and other nootropics • The safest delivery forms (and the ones to avoid) • Whether nicotine supports or hinders longevity and cognitive resilience • How it can be stacked with supplements, fasting, or ketosis • What functional medicine says about chronic use, addiction, and withdrawal This is essential listening for anyone serious about biohacking, human performance, and longevity, and for those who want to understand how functional biology and mitochondrial science are redefining recovery, energy, and aging. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: Nicotine microdosing, Nicotinic acetylcholine receptors, Dopamine and motivation, Cognitive enhancement, Alzheimer's prevention, Neuroinflammation, Mitochondrial function, TNF-alpha reduction, Vagus nerve activation, Longevity biohacking, Nicotine vs smoking, Nootropics, Attention and vigilance, Ketosis and metabolism, Functional medicine, Nicotine patches and gum, Addiction and tolerance, Receptor desensitization, Withdrawal protocols, Deep work performance Thank you to our sponsors! -TRU KAVA | Go to https://trukava.com/ and use code DAVE10 for 10% off. -HeartMath | Go to https://www.heartmath.com/dave to save 15% off. -Leela Quantum Tech | Check out all HEAL360 products and research and get 10% off at https://leelaq.com/DAVE. -Calroy | Head to https://calroy.com/dave for an exclusive discount. Resources: • Business of Biohacking | Register to attend October 20-23 in Austin, TX https://businessofbiohacking.com/ • Danger Coffee: https://dangercoffee.com/discount/dave15 • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Introduction 1:27 — History & Background of Nicotine 4:34 — How Nicotine Works 15:12 — Benefits & Research 16:43 — Risks & Who Should Avoid It 21:39 — Delivery Methods & Dosing 26:30 — Conclusion & Next Steps See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Review the 2020 ACLS Atropine and Dopamine guidelines for the treatment of unstable bradycardia, including: dosing, administration, and precautions.When we should use the bradycardia algorithm.The signs & symptoms of unstable bradycardia.Atropine's bradycardic dose and maximum.The use of atropine when a patient is in a second degree type II or third degree heart block.ECG changes that indicate subsequent doses of atropine are likely to be ineffective.The starting dose of Dopamine.The use of Dopamine for bradycardia as an interim until TCP vs hypotension.The use of Atropine and Dopamine in patients with myocardial ischemia.Podcasts with additional (advanced-provider level) information about bradycardia, Atropine, & Dopamine can be found on the Pass ACLS Pod Resources page.**American Cancer Society (ACS) Fundraiser This is the seventh year that I'm participating in Men Wear Pink to increase breast cancer awareness and raise money for the American Cancer Society's life-saving mission.I hope you'll consider contributing.Every donation makes a difference in the fight against breast cancer! Paul Taylor's ACS Fundraiser Page: http://main.acsevents.org/goto/paultaylorTHANK YOU for your support! Good luck with your ACLS class!Links: Buy Me a Coffee at https://buymeacoffee.com/paultaylor Free Prescription Discount Card - Get your free drug discount card to save money on prescription medications for you and your pets: https://safemeds.vip/savePass ACLS Web Site - Other ACLS-related resources: https://passacls.com@Pass-ACLS-Podcast on LinkedIn

Dhineli Perera talks to infectious diseases physician and clinical microbiologist Carly Hughes about the latest recommendations for aminoglycoside use in Australia. They discuss indications for parenteral aminoglycosides, drug selection, dosing and therapeutic drug monitoring. Read the full article by Carly and her co-authors in Australian Prescriber.

Drs. Erin Barreto (@erin_barreto) and Jeffrey Lipman join Dr. Whitney Buckel for a conversation on ideal dosing of cefepime. Hear from the experts on the differences between package insert and “high-dose” regimens, adjustments for renal impairment/augmented renal clearance, and the role of cefepime therapeutic drug monitoring. References: Barreto EF, et al. Setting the Beta-Lactam Therapeutic Range for Critically Ill Patients: Is There a Floor or Even a Ceiling? Crit Care Explor. 2021 Jun 11;3(6):e0446.PMID: https://pubmed.ncbi.nlm.nih.gov/34136822/ Barreto EF, et al. Adequacy of cefepime concentrations in the early phase of critical illness: A case for precision pharmacotherapy. Pharmacotherapy. 2023 Nov;43(11):1112-1120. https://pubmed.ncbi.nlm.nih.gov/36648390/ ** **Udy AA, et al. Augmented renal clearance: implications for antibacterial dosing in the critically ill. Clin Pharmacokinet. 2010;49(1):1-16. https://pubmed.ncbi.nlm.nih.gov/20000886/ Lipman J, Wallis SC, Boots RJ. Cefepime versus cefpirome: the importance of creatinine clearance.   Anesth Analg. 2003 Oct;97(4):1149-1154. doi: 10.1213/01.ANE.0000077077.54084.B0.PMID: 14500173 Roberts JA, Ulldemolins M, Roberts MS, McWhinney B, Ungerer J, Paterson DL, Lipman J. Therapeutic drug monitoring of beta-lactams in critically ill patients: proof of concept.  Int J Antimicrob Agents. 2010 Oct;36(4):332-9. doi: 10.1016/j.ijantimicag.2010.06.008. Epub 2010 Aug 3.PMID: 20685085

Show NotesIn this special live episode from the 2025 North American Congress of Clinical Toxicology (NACCT), Ryan takes you inside the conference to hear directly from the researchers themselves. Covering 11 abstracts that span high-stakes management decisions, surprising case reports, and challenges to toxicology dogma, this year's highlights feature everything from amlodipine overdoses to naturopathic misadventures, metformin-associated blindness, and more. The show kicks off with a foreword from Ryan and Dr. Jon Cole (abstract co-chair for AACT) discussing some of their favorite research from the conference. If you couldn't make it to NACCT or just want to catch up on some of the most impactful new research in our field, this episode will give you a front-row seat. Check below for links to the published abstracts, the full list of studies discussed, and timestamps for where you can hear each one.Link to published abstract manuscriptForeword with Dr. Jon Cole 10:24 #7. Is beta blocker toxicity associated with hypoglycemia?Lead author: Dr. Megan Audette, MD17:58 #237. V-A ECMO as a treatment for vasoplegic shock in amlodipine poisoning: a comparisonLead author: Dr. Daniel Tirado, MD27:59 #247. Blocked but not beaten: ECMO's role in severe amlodipine toxicity – a poison center case seriesLead author: Dr. Carlos Saldarriaga, MD28:39 #26. Amlodipine double-dose therapeutic errors reported to Poison CentersLead author: Johanne Freeman30:19 #27. Dosing on the edge: unpacking inadvertent amlodipine ingestions reported to a single poison centerLead author: Dr. Tiana Patriarca, PharmD33:44 #292. Intravenous administration of sodium zirconium cyclosilicate resulting in deathLead author: Dr. Stephen Thornton, MD Researcher interviews43:57 – #21. Quantitative analysis of amlodipine removal by plasmapheresisGuest: Dr. Keahi Horowitz, MD – Acute and Intensive Care Research Award winner48:14 – #23. Relationship between reported ingestion dose and outcome in amlodipine poisoningGuest: Dr. Colleen Cowdery, MD51:18 – #24. Management of severe amlodipine toxicity with high-dose calcium aloneGuest: Dr. Vincent Ma, MDHigh dose norepinephrine in amlodipine overdose Case report of calcium death 56:37 – #70. Iatrogenic exposure to long-acting buprenorphine injectable in an opioid-naïve patientGuest: Dr. Conor Young, MD59:52– #182. Left in the dark: a case of blindness in the setting of metformin toxicityGuest: Dr. Madison Bombard, MD61:52 – #169. Just because it's natural doesn't mean it's safe: a case of pediatric toxicity from topical and herbal remediesGuest: Dr. Aria Darling, MD64:12 – #203. Serotonin syndrome after vaping MoocahGuest: Dr. Connor Murphy, MD66:47 – #307. Intravenous ozone autohemotherapy: a retrospective observational case seriesGuest: Nicole McLarty 71:06 – #134. Do they really need n-acetylcysteine? Exploratory analysis of outcomes in patients with elevated liver function

Should GA therapy start monthly—or is less-than-monthly treatment enough? In episode 3 of this New Retina Radio miniseries, moderator John Kitchens, MD joins David Eichenbaum, MD; Margaret Chang, MD, MS; and Ferhina Ali, MD, MPH, to share best practices in real-world GA care. The panel debates dosing strategy in light of long-term data, compares safety/efficacy considerations for pegcetacoplan vs avacincaptad pegol (including first-injection inflammation risk), and offers tips for initiating therapy in monocular patients. They also unpack evidence around AREDS vitamins and early experiences with photobiomodulation.This content is editorially independent, supported by Astellas Pharma.

Most people chase fat loss, focus, and energy with caffeine or stimulants, but the real key to brain optimization and human performance is a pharmaceutical nootropic that activates your wakefulness circuits without jitters or a crash. In this episode, you'll learn how Modafinil upgrades mitochondria, sharpens neuroplasticity, improves metabolism, and extends longevity with evidence-based tools used by elite thinkers, fighter pilots, and world leaders. This is not a sales pitch. It is an educational masterclass on how to upgrade your brain beyond what it can ever do naturally. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey takes you inside the full playbook of Modafinil, a prescription nootropic often called the “real Limitless pill.” With over 20 years of personal experience using it daily alongside biohacking stacks of supplements, fasting, ketosis, cold therapy, sleep optimization, and Danger Coffee, Dave explains why Modafinil is more than just a wakefulness drug. It is a brain optimization tool that supports mitochondrial energy, resilience, and cognitive clarity. Together with decades of research, Dave shows you how Modafinil compares to stimulants like Adderall and caffeine, why it was adopted by Air Force pilots and Wall Street executives, and how functional medicine strategies can help you safely integrate it into a broader biohacking and longevity stack. This is a masterclass in hacking cognition and performance, designed for anyone who wants a sharper brain, stronger metabolism, and a more resilient body. You'll learn: • How Modafinil works as a nootropic without overstimulating dopamine • The connection between mitochondria, neuroplasticity, and human performance • Why Modafinil may protect against brain aging and inflammation • How to dose, stack, and cycle Modafinil with supplements and nutrition • What to expect from Modafinil compared to stimulants like Adderall or caffeine • The risks, side effects, and who should avoid it This is essential listening for fans of biohacking, hacking human performance, functional medicine, and longevity who want actionable tools from Host Dave Asprey and a transparent look at the world's most famous cognitive enhancer. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday (audio-only), and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: Modafinil, Armodafinil, Adrafinil, Real Limitless pill, Smart drugs, Eugeroic drug, Nootropics for focus, Orexin activation, Dopamine modulation, Mitochondria ATP production, Neuroplasticity enhancers, Jet lag treatment, ADHD alternative, Poker player focus enhancer, Modafinil stack, Modafinil and L-theanine, Modafinil and NAD+, Modafinil side effects, Stevens Johnson syndrome risk, Alzheimer's prevention modafinil Thank you to our sponsors! Essentia | Go to https://myessentia.com/dave and use code DAVE for $100 off The Dave Asprey Upgrade. BodyHealth | Go to https://bodyhealth.com/ and use code DAVE20 to save 20% off your first order of PerfectAmino. ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order. Resources: • Danger Coffee: https://dangercoffee.com/discount/dave15 • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: • 0:00 — Trailer • 1:22 — Origin of Modafinil • 3:48 — Personal Experience • 8:22 — What to Expect • 9:37 — What Is Modafinil • 16:09 — How Modafinil Works • 19:36 — Benefits & Cognitive Upgrades • 25:36 — Dosing, Stacking, and Usage Tips • 28:17 — Side Effects and Safety • 31:37 — Sourcing and Legal Aspects • 36:55 — Research and Future Uses • 42:17 — Stacking for Biohacking • 47:07 — Recap and Final Advice See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Today, I'm sitting down with Alex Tarnava and Dr. Tyler LeBaron, two of the brightest minds pioneering the use of molecular hydrogen in health optimization. Alex, the innovative creator behind the open cup hydrogen tablet technology, and Dr. LeBaron, founder of the Molecular Hydrogen Institute, join me to shed light on why this tiniest molecule could be the secret weapon in your longevity toolkit. We dive into their personal stories—Alex's relentless search for relief from autoimmune symptoms, and Dr. LeBaron's early curiosity that led him to decades of hydrogen research and advocacy.   To learn more visit  inhaleh2.com/NAT. There is a special discount between 20% - 24% percent off, depending on your pre-order.   Episode Timestamps: What is molecular hydrogen? ... 00:00:31 Guest backgrounds and early hydrogen research ... 00:04:37 Hydrogen's biological role and health benefits ... 00:09:24 Alex's personal health journey and invention ... 00:16:24 Clinical trials and real-world benefits ... 00:26:01 Hydrogen as a selective antioxidant ... 00:34:20 Inflammation, mitochondria, and aging ... 00:45:47 Delivery methods: water, inhalation, bathing ... 00:58:16 Dosing tips and protocols ... 01:14:21 Inhalation machines: safety and efficacy ... 01:17:47 Safety, final advice, and resources ... 01:26:26   Our Amazing Sponsors: StemRegen - A plant-based supplement protocol designed to enhance stem cell function. support your recovery, flexibility, and long-term vitality. Visit stemregen.co/NAT15 and use code: NAT15 for 15% off your order.   Puori - It's minimally processed, made from pasture-raised cows' milk, and it's tested for over 200 contaminants every single batch. Go to Puori.com/NAT and use code NAT for 20% off— it also applies to subscriptions so you'll get nearly a third off the price. OraltidePro- A unique mouthwash that: Promotes growth of shrinking gums, Speeds healing of mouth & tongue, Prevents oral infections (such as gingivitis), Helps with enamel remineralization, Reduces bacteria growth and etching and Fills slots in damaged enamel. check out OraltidePro at profound-health.com and use code NAT15 for 15% off your first order.   Nat's Links:  YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

Get My Book On Amazon: https://a.co/d/avbaV48DownloadThe Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/1 On 1 Coaching Application: https://hunterwilliamscoaching.carrd.co/Book A Call With Me: https://hunterwilliamscall.carrd.co/Supplement Sources: https://hunterwilliamssupplements.carrd.co/Amazon Storefront: https://www.amazon.com/shop/hunterwilliams/list/WE16G2223BXA?ref_=cm_sw_r_cp_ud_aipsflist_R7QWQC0P1RACB2ETY3DYSocials:Instagram: https://www.instagram.com/hunterwilliamscoaching/Podcast: https://hunterwilliamspodcast.buzzsprout.com/Video Topic Request: https://hunterwilliamsvideotopic.carrd.co/In today's video I unpack amlexanox—an old anti-inflammatory/allergy drug with surprising metabolic effects. I share my first encounter with it in the research-chem world, what I noticed subjectively, and then dive into mechanisms (IKKε/TBK1 inhibition, catecholamine resensitization, beige fat), rodent data, the Phase 2 human trial (150 mg/day), safety, dosing, who seems to respond best, and how I'm stacking it inside Bio Ignite. If your goal is fat loss with stubborn adipose inflammation, this is worth understanding.0:00 - Welcome + what today's video covers0:28 - How I first found “AM Lox” browsing catalogs1:06 - Cycling off SLU-PP-332 and first personal trial1:40 - Noticing dryness/ab definition; early under-dosing2:12 - 2025 “sugar diet” + hunting for FGF21 boosters2:40 - Finding data that amlexanox increases FGF213:02 - Literature dosage (100–150 mg) vs my early dose3:38 - Why I think it's a useful fat-loss rotation tool4:24 - Channel/hosting update + where to find my videos5:08 - Slides start: what amlexanox is/was used for6:00 - Core mechanism: IKKε/TBK1 → PDE3B → cAMP resistance7:16 - IL-6→STAT3 hepatic signaling + beigeing via FGF218:30 - Big-picture benefits: inflammation, insulin sensitivity, glycemia10:32 - Human data: Phase 2 trial (150 mg/day x 12 weeks)11:10 - Modest/variable weight change; who improved most12:37 - Practical takeaways: glycemia, liver fat, insulin sensitivity14:12 - Dosing in practice (50 mg caps, TID = 150 mg/day)15:12 - Responder phenotype: high adipose inflammation16:00 - Who benefits most + variability at similar body fat17:56 - Study roll-up and mechanism recap18:52 - Final thoughts, use-cases, and product note (Bio Ignite)19:54 - Thank you + where to grab the peptide cheat sheetWhat You'll LearnWhy amlexanox can “release the brakes” on fat-burning by inhibiting IKKε/TBK1 and restoring cAMP/catecholamine responsiveness.How it raises IL-6 transiently in adipose, activates STAT3 in the liver, suppresses gluconeogenesis, and increases FGF21 to promote beige fat programs.The mouse vs. human gap: robust fat loss in mice; in humans, clearer improvements in A1c, fructosamine, liver fat, insulin sensitivity—especially when adipose inflammation is high.Dosing used in the Phase 2 trial: 50 mg TID (total 150 mg/day) for 12 weeks.Safety snapshot: no serious AEs attributed to amlexanox in metabolic trials; most common was a transient rash.Timestamps (exact to the transcript)What you'll learn

Unlock sharper focus and support long-term brain health with Ketone-IQ—clean brain fuel for deep work, mental clarity, and sustained energy with no crash. Get 30% off your subscription, plus a free gift with your second shipment at Ketone.com/vanessa. In this powerful second interview, Dr. Latt Mansor returns to the podcast to share his personal 20+ lb fat loss transformation—and how he used ketones and strategic carb re-feeds to break through stubborn plateaus, curb hunger, and preserve lean muscle mass. NEW! Support your strength and muscle goals with PUORI Creatine+ — a clean, effective creatine monohydrate supplement enhanced with magnesium and vitamin B12. Get 20% off at puori.com/VANESSA We dive into: How to use ketones to improve fat loss quality (not just scale weight) Why Dr. Mansor says ketones helped him “lose fat without losing muscle” How carb re-feeds helped him overcome plateaus and support metabolic flexibility How ketones support appetite control, recovery, and training performance A new study showing ketones boost sprint output and reduce fatigue Ketones vs. GLP-1 drugs like Ozempic—how they compare for appetite suppression Dosing protocols for fat loss, fasting, and late-night cravings How ketones improve oxygen delivery, red blood cell production, and reduce cortisol The science behind ketones reducing muscle protein breakdown and supporting performance Ketones and the brain: supporting focus, anxiety, ADHD, and GABA signaling If you've hit a fat loss plateau—or want to preserve muscle while losing fat—this episode is packed with cutting-edge science and tools on how to use exogenous ketones and strategic carbs to support metabolic health, performance, and sustainable results. Connect with Vanessa on Instagram @ketogenicgirl Free High-Protein Keto Guide  Get 20% off on the Tone LUX Crystal Red Light Therapy Mask or the Tone Device breath ketone analyzer at https://ketogenicgirl.com with the code VANESSA Follow @optimalproteinpodcast on Instagram to see visuals and posts mentioned on this podcast. Link to join the Facebook group for the podcast The content provided in this podcast is for informational purposes only and should not be construed as medical advice. Consult with a healthcare professional before making significant changes to your diet or exercise regimen.

Karen tackles a listener question about low-dose lithium. She reviews micro- vs. low-dose ranges, discusses forms like lithium orotate/aspartate and third-party-tested supplement options, and flags safety essentials such as toxicity symptoms, thyroid/kidney considerations, and when to loop in your clinician.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.

In this episode, Sam Ashoo, MD and T.R. Eckler, MD discuss the September 2025 Emergency Medicine Practice article, Emergency Department Management of Patients With Status Epilepticus Topic IntroductionFocus: Status Epilepticus in AdultsReference to recent pediatric episodeArticle authors: Dr. Marquez, Dr. Kaur, Dr. LayWhy Status Epilepticus MattersTeaching value and clinical challengeTeam-based care and multidisciplinary involvementGuidelines and EvidenceReview of major guidelines (International League Against Epilepsy, Neurocritical Care Society, American Epilepsy Society)Key trials: EcLiPSE, ConSEPT, ESETTUpdated definition of status epilepticusClassification and DiagnosisConvulsive vs. non-convulsive statusImportance of repeated neurologic examsDiagnostic challenges and mimics (e.g., syncope, psychogenic seizures)Etiology and WorkupAcute vs. non-acute causesCommon triggers: medication noncompliance, metabolic issues, infections, traumaImportance of sleep patterns and ammonia levelsThe NORSE acronym (new onset refractory status epilepticus)Prehospital and ED ManagementAirway, breathing, circulation prioritiesEarly pharmacologic intervention (IM midazolam preferred in prehospital)Gathering history and medication informationPositioning and airway protectionDiagnosticsLaboratory workup: glucose, CBC, metabolic panel, drug levels, pregnancy testImaging: non-contrast CT, MRI, ultrasound, lumbar punctureEEG: spot vs. continuous monitoringTreatment ApproachFirst-line: Benzodiazepines (lorazepam, midazolam)Second-line: Levetiracetam, valproate, fosphenytoin, phenobarbital, lacosamideThird-line: Continuous infusions (midazolam, propofol, pentobarbital, thiopental, ketamine)Dosing pearls and importance of rapid escalationSpecial PopulationsPregnancy (eclampsia: magnesium as first-line)Substance-induced status epilepticus (e.g., isoniazid toxicity and pyridoxine)Brief mention of pediatric management and the PD stat appRisk Management PitfallsNon-convulsive status is common and easily missedImportance of weight-based dosingNeed for formal EEG in ambiguous casesDon't assume non-adherence is the only cause in known epilepticsAlways consider higher level of care for status patientsClinical PathwayStepwise approach to medication and escalationEmphasis on having a pathway/checklist for these high-stress casesConclusionRecap of key pointsThanks to authors and listenersReminder to visit ebmedicine.net for CME and resourcesEmergency Medicine Residents, get your free subscription by writing resident@ebmedicine.net

Get My Book On Amazon: https://a.co/d/avbaV48Download The Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/1 On 1 Coaching Application: https://hunterwilliamscoaching.carrd.co/Book A Call With Me: https://hunterwilliamscall.carrd.co/Supplement Sources: https://hunterwilliamssupplements.carrd.co/Amazon Storefront: https://www.amazon.com/shop/hunterwilliams/list/WE16G2223BXA?ref_=cm_sw_r_cp_ud_aipsflist_R7QWQC0P1RACB2ETY3DYSocials:Instagram: https://www.instagram.com/hunterwilliamscoaching/Podcast: https://hunterwilliamspodcast.buzzsprout.com/Video Topic Request: https://hunterwilliamsvideotopic.carrd.co/0:00 - Intro: why I'm covering Testagen0:30 - The low-T epidemic and TRT context1:12 - Why I'm excited about Testagen vs HCG2:00 - What I'll cover today (what it does, dosing, use cases)2:40 - What Testagen is (KEDG bioregulator peptide)3:12 - Mechanisms and “does this help women?” note4:00 - Core effects: endocrine support + epigenetic action5:00 - Target tissues: pituitary, thyroid, testes, bone marrow6:00 - Vascular/erectile benefits; “calibrating” the HPT axis6:30 - Fertility use case + my personal plan7:16 - Manufacturer indications; sexual function improvements8:12 - Case study: semen parameters quadrupled on Testolutin8:58 - Thyroid support, TBI/central hypo considerations9:58 - Anti-aging & immune modulation overview10:20 - Human evidence: oral Testolutin study (TT, LH/FSH ↑)11:02 - Human evidence: IM Testagen (2.5 mg x 10 days) results11:48 - 2022 combo study (4-peptide stack; free T ↑ ~54%)13:08 - Animal data: pituitary-independent thyroid restoration14:08 - Cell data: nuclear entry, histone/DNA binding14:34 - Outcomes summary: testosterone, LH/FSH, libido15:02 - Testagen vs TRT; stacking with Epitalon/Epithalamin16:01 - Safety profile: “no significant side effects” noted16:56 - Dosing protocol I recommend (2 mg/day, 10–60 days)17:24 - Full male-health stack ideas (Testagen + others)17:40 - Big-picture takeaway: who benefits most18:10 - Real-world reports, call for comments, and thanksI break down Testagen (a KEDG bioregulator) as a legit pathway to support testicular function, HPT axis “calibration,” and fertility—without typical TRT downsides. I walk through how it works at the epigenetic level (nuclear entry, histone/DNA interaction), human and animal evidence (oral Testolutin and injectable Testagen), thyroid and immune benefits, erectile/vascular support, and what I've seen in early adult men with low T. I also share my fertility plan, practical dosing (2 mg/day; 10–60 days), and how I'd pair Testagen with peptides like Epitalon, Libidon, Glandokort, and Superfort for broader rejuvenation. If you've used Testagen, drop your experience—wins or misses—so we can help the community learn what's working.

What happens when you stop taking progesterone, even for just a few weeks? In this quick episode, I'm sharing my personal story of running out of progesterone, how my symptoms came rushing back, and why this hormone is so important for women in perimenopause. You'll learn why dosing and delivery methods matter, common signs of low progesterone, and how we help clients find a provider who actually understands women's hormones. I covered: My story of running out of progesterone and the symptoms that returned How progesterone is the first hormone to decline after 35 Common signs of low progesterone: mood swings, anxiety, poor sleep, heavy periods The pros and cons of oral, vaginal/rectal, and topical progesterone Why dosing matters (too low can trigger “estrogen kickback”) Why it's vital to find a hormone-savvy provider who listens and prescribes appropriately   WATCH ON YOUTUBE: https://youtu.be/CQ9YF9Go43k   Links Mentioned: Ona's Natural Progesterone Cream Moods, Emotions, and Aging: Hormones and the Mind-Body Connection by Phyllis Bronson Episode 32: Progesterone: The Miracle Hormone w/ Carol Petersen (Registered Pharmacist)   LOVE THE SHOW? Please subscribe, leave a 5-star rating, review, and share with other women, so they can get the support they need in perimenopause!    CONNECT WITH CLAUDIA:  Website YouTube Instagram Facebook Inquiries   FREE RESOURCES:  Peri-What?! The Must-Have Guide for Women 40+ Navigating Hormone Changes Perimenopause Daily Checklist HRT 3-Day Crash Course   GET SUPPORT:  Perimenopause Clarity Session The Perimenopause Method Program Perimenopause HRT Roadmap Course   PRODUCTS WE LOVE: Equip Prime Protein (Save 15% w/ code: healthcoachclaudia) Microbiome Labs Total Gut Restoration (Save 15% w/ code: claudia123) BodyHealth Reds & Greens Powders Symphony Natural Health Melatonin Glow Below Vaginal Estrogen or DHEA For more products we recommend, click HERE.

In today's VETgirl online veterinary continuing education podcast, we're diving into a recent study that may reshape how we manage feline infectious peritonitis (FIP), especially  around treatment dosing and duration. With growing success using antiviral therapy for this once considered “universally fatal” disease, we now have the opportunity to refine our protocols based on real-world outcomes. So today we are reviewing the exciting findings of this article by Kamiyoshi et al entitled “High-dose induction therapy and treatment termination criteria for feline infectious peritonitis with remdesivir, GS-441524 and adjunctive mefloquine: 46 cases (2023).”

Do you ever wonder how to safely use herbal medicine at home? Whether it's tinctures, teas, powders, or capsules, figuring out the right dose can feel a little overwhelming, especially if you're just starting out. In this week's Pantry Chat, I'm joined by Dr. Patrick Jones from HomegrownHerbalist.net to break it all down in a simple, practical way.We're covering:

Show notes at pharmacyjoe.com/episode1054. In this episode, I'll discuss the optimal dosing regimen for meropenem and piperacillin/tazobactam in critically ill patients receiving continuous renal replacement therapy. The post 1054: What is the optimal meropenem and piperacillin/tazobactam dosing regimen for critically ill patients receiving continuous renal replacement therapy? appeared first on Pharmacy Joe.