Podcasts about diagnostic

In this episode, Dr. Rena Malik was joined by Dr. Richard Natale, Dr. Rachel Mann, and Dr. Paul Rusilko and the conversation focused on the comprehensive evaluation and management of erectile dysfunction, including diagnostic workups, the role of penile Doppler, and the impact of underlying health conditions and medications. Several points were raised about the importance of individualized treatment plans, addressing pelvic floor dysfunction, and the effects of lifestyle factors like cycling and masturbation. Become a Member to Receive Exclusive Content: renamalik.supercast.com Schedule an appointment with me: https://www.renamalikmd.com/appointments ▶️Chapters: 00:00 Diagnostic workup for ED00:44 Role of penile Doppler02:01 Venous leak discussion06:45 Treatment options for venous leak08:09 Clinic quality concerns11:08 Can reversing health conditions help ED?13:05 Medications causing ED14:55 Combination/off-label therapies15:50 Cycling and erectile dysfunction17:39 Pelvic floor dysfunction19:37 Depression and erectile dysfunction22:37 Death grip syndrome & masturbation habits27:13 Semen retention myths30:21 Oral medications and ED treatments Stay connected with Dr. Richard Natale, Dr. Rachel Mann, and Dr. Paul Rusilko on social media for daily insights and updates. Don't miss out—follow them now and check out these links! Dr. Richard Natale INSTAGRAM - https://www.instagram.com/cltmenshealth/ FACEBOOK - https://www.facebook.com/DrRichardNatale/ YOUTUBE - https://www.youtube.com/channel/UC7f0TcwCph3edIWVsXeyFRw Dr. Rachel Mann INSTAGRAM - https://www.instagram.com/you_the_mann/ X - https://x.com/You_the_Mann?lang=en Dr. Paul Rusilko INSTAGRAM: https://www.instagram.com/drpaulrusilko/ https://www.instagram.com/upmcurology/ X: https://x.com/UPMCUrolog https://x.com/PaulRusilko Let's Connect!: WEBSITE: http://www.renamalikmd.com YOUTUBE: https://www.youtube.com/@RenaMalikMD INSTAGRAM: http://www.instagram.com/RenaMalikMD TWITTER: http://twitter.com/RenaMalikMD FACEBOOK: https://www.facebook.com/RenaMalikMD/ LINKEDIN: https://www.linkedin.com/in/renadmalik PINTEREST: https://www.pinterest.com/renamalikmd/ TIKTOK: https://www.tiktok.com/RenaMalikMD ------------------------------------------------------ DISCLAIMER: This podcast is purely educational and does not constitute medical advice. The content of this podcast is my personal opinion, and not that of my employer(s). Use of this information is at your own risk. Rena Malik, M.D. will not assume any liability for any direct or indirect losses or damages that may result from the use of information contained in this podcast including but not limited to economic loss, injury, illness or death. Learn more about your ad choices. Visit megaphone.fm/adchoices

Send Katie a Text Message!! Being overwhelmed doesn't automatically mean your interior design firm needs another employee.In Part 4 of The Design Business Diagnostic, I'm diving into Human Capital—and one of the biggest mistakes I see growing design firms make. Some owners are dramatically under-invested in people and have made themselves the bottleneck in practically every area of the company. Others have built expensive teams with overlapping responsibilities and still haven't created meaningful capacity.Both situations can leave the owner exhausted. They require very different solutions.  Pasted markdownIn this episode, I'm talking about:How to tell whether your firm is under-supported or overstaffedWhy “I need help” isn't specific enough to make a hiring decisionThe cost of hiring versus the often-ignored cost of not hiringWhy I want you to start with the work instead of the personThe three categories I use to audit an owner's workloadWhy an assistant designer may not be the first hire your firm actually needsHow bookkeeping, administrative support, procurement, and operations can create leverageWhy hiring doesn't automatically mean adding a full-time employeeThe difference between giving someone responsibility and giving them authorityHow vague roles create expensive duplicationWhy refusing to invest in people can eventually create a revenue ceilingThe qualities I value when hiring that go beyond technical skillHow to conduct a Human Capital audit of your own firmThe goal isn't to build the biggest team. It's to determine what your business needs and create the right combination of people, systems, and outside resources to accomplish it profitably.If you're looking at your team—or lack of one—and aren't sure whether you need to hire, restructure, outsource, or make a different investment, book a complimentary Business Diagnostic Call at FixMyDesignBiz.com. We'll diagnose what your business actually needs instead of starting with a generic org chart. Connect with KatieLinkedInBusiness Strategy Sessions for Interior Designers Free Resources for scaling your interior design firmWebsite

LIVE from ILADS: Tick Boot Camp reconnects with Nicole Bell, CEO of Galaxy Diagnostics, for a focused conversation about one of the biggest challenges in Lyme disease and tick-borne illness: getting an accurate diagnosis. Bell breaks down the differences between antibody testing, antigen testing, and PCR-based direct detection while explaining why stealth pathogens such as Borrelia, Bartonella, and Babesia can be so difficult to find. She also introduces Galaxy's BBB Direct Detect digital PCR testing, discusses emerging findings involving Babesia species, and explains why a negative antibody test doesn't always tell the entire story. For Bell, the mission is deeply personal. Her husband, Russ, initially tested negative for Lyme disease and was later diagnosed with Alzheimer's disease before his family ultimately discovered tick-borne infections were part of his complex illness. That experience helped redirect Bell's engineering and medical technology background toward improving diagnostics for other patients searching for answers. This interview was recorded live at the ILADS conference, so you may hear some of the energy and background activity of the event throughout the conversation. Why Can Lyme Disease Testing Be So Difficult? Bell begins by explaining one of the fundamental problems with diagnosing Lyme disease and other tick-borne infections: many of the pathogens clinicians are searching for can be difficult to detect. Some occur at low levels in the bloodstream. Others may migrate into tissues or circulate intermittently. Historically, much of tick-borne disease testing has therefore relied on indirect detection — looking for the patient's immune response rather than directly detecting the organism. Antibody testing can provide useful information, but Bell explains why interpretation can become complicated. A patient's antibody response can vary depending on factors including: Timing of infection Individual immune response Immune suppression or dysregulation Previous exposure Previous treatment Medications that suppress immune activity Cross-reactivity Whether an infection is current or historical This is why Bell views antibody testing as one tool rather than the entire diagnostic toolbox. Antibody Testing: Detecting the Immune Response Antibody testing is an indirect testing method. Instead of looking for Borrelia itself, for example, the test looks for evidence that the patient's immune system has responded to it. Bell discusses IgM and IgG antibodies and why timing matters. IgM antibodies are generally associated with an earlier immune response, while IgG responses can take longer to develop. In Lyme disease, that delay creates a particular challenge because early diagnosis and treatment can be especially important. Some infected patients may mount a strong measurable antibody response, while others may produce a weaker or delayed response. Bell points to research showing how dramatically immune responses can differ even under controlled experimental conditions. This creates an important distinction: A test of the immune response is not necessarily the same thing as a test for the pathogen itself. When Antibodies Don't Tell the Whole Story Bell uses her husband's experience to illustrate the stakes. Russ had likely been ill for years before his most significant symptoms emerged. By then, Bell says his immune system was dysregulated and his overall antibody levels were low. His Lyme testing was negative, and his worsening cognitive symptoms ultimately led to an Alzheimer's diagnosis. There is also another side to antibody testing. A person may have antibodies because of a previous infection even when the original infection is no longer active. That can make it difficult to determine whether persistent symptoms are associated with an ongoing infection, an undiagnosed coinfection, immune dysregulation, or another process. Bell's point is not that antibody testing has no value. It is that complex tick-borne illness may require more than one diagnostic tool. Antigen Testing: Looking for Evidence of the Pathogen The conversation then moves from indirect testing to direct detection. One method is antigen testing. Rather than measuring the immune system's response, an antigen test searches for a component associated with the pathogen itself. Bell discusses Galaxy's work with a urine-based Lyme disease antigen approach designed to capture and concentrate a protein shed by Borrelia. Why urine? Bell explains that Lyme-causing Borrelia may not remain abundantly present in the bloodstream. A pathogen-derived protein, however, may be filtered through the kidneys and become detectable in urine. Galaxy continues to work on direct-detection approaches to Lyme disease testing as it pursues broader clinical adoption and regulatory pathways. PCR Testing: Searching for Pathogen DNA Another form of direct detection is PCR testing. PCR looks for genetic material from the pathogen rather than relying on the patient's antibody response. Galaxy uses PCR-based approaches for pathogens including: Borrelia Bartonella Babesia But direct detection presents its own challenge. These organisms may occur at extremely low levels in a sample. A patient can be infected while very little pathogen DNA happens to be circulating in the particular blood sample collected that day. That is where digital PCR, or dPCR, becomes especially interesting. The Three B's: Borrelia, Bartonella & Babesia Bell introduces Galaxy's approach to what Tick Boot Camp often calls the Three B's: Borrelia. Bartonella. Babesia. As patient and clinician awareness of tick-borne illness has evolved, these three pathogens have become increasingly important to the conversation around complex cases. Galaxy's BBB Direct Detect digital PCR testing is designed to directly detect DNA from Borrelia, Bartonella, and Babesia. Unlike an antibody test asking whether the immune system has responded to a pathogen, direct PCR testing asks a different question: Can we find genetic evidence of the organism itself? How Digital PCR Searches for Low-Abundance Pathogens Bell gives a simple analogy for understanding digital PCR. Imagine searching for a needle in a haystack. Traditional PCR is trying to identify a tiny amount of pathogen DNA — the needle — among an enormous amount of human genetic material — the haystack. Digital PCR effectively divides that haystack into thousands of much smaller piles and examines them individually. That partitioning can make it easier to detect extremely small amounts of genetic material. Galaxy also uses a culture-enrichment step for Bartonella. The blood sample is placed in an environment designed to encourage Bartonella growth before PCR analysis, increasing the amount of target material available for detection. Learn more about Galaxy Diagnostics' direct-detection technology and its approaches to Borrelia, Bartonella, and Babesia testing. Why Are We Seeing So Many Coinfections? Tick Boot Camp and Bell also discuss an observation that has become increasingly common in patient interviews: many people with complex chronic tick-borne illness aren't reporting only Lyme disease. Instead, patients frequently describe combinations involving the Three B's and other infections. Why? Bell says several factors may contribute. Diagnostic technology has improved. Clinicians have become more aware of coinfections. Ecological research indicates ticks can carry multiple pathogens. But Bell raises another important possibility: patients carrying multiple pathogens may also be among those who become the sickest and therefore are disproportionately represented within chronic illness communities. That distinction matters. Observing many coinfections among severely ill patients doesn't necessarily mean every tick-borne disease patient has the same microbial picture. Bartonella, the Immune System & the Tipping Point Bell discusses Bartonella as an example of the complexity surrounding infection and illness. Exposure may be more common than many people realize, and Bartonella has multiple potential vectors and reservoirs. Bell describes a hypothesis in which some people may harbor an infection while their immune system keeps it under control. Then another infection, environmental exposure, significant stressor, or other immune-disrupting event may alter that balance. A person who had previously remained relatively healthy may cross what Bell describes as a tipping point and begin experiencing significant illness. This raises questions researchers are still working to answer. Were multiple infections transmitted simultaneously? Did they occur through separate exposures? Was one infection already present before another destabilized the immune system? Bell emphasizes that the answer may differ from patient to patient. Emerging Questions About Babesia Some of the most intriguing discussion in this interview involves Babesia. Bell explains that research associated with the North Carolina State University team has identified Babesia species in complex patients beyond the organisms traditionally emphasized in U.S. human babesiosis. She specifically discusses findings involving Babesia odocoilei and Babesia divergens-like organisms and contrasts those findings with expectations surrounding Babesia microti and Babesia duncani. Bell also discusses the possibility of low-level parasitemia — infections involving pathogen levels that may be much lower than the classic severe presentation clinicians associate with babesiosis. These emerging observations raise important research questions about Babesia species, their prevalence, their role in human disease, and whether existing diagnostic assumptions capture the full picture. Bell is careful in the interview to distinguish between what Galaxy's current assay detects and what researchers may suspect based on sequencing and related scientific work. Nicole Bell's Personal Mission Bell's work in tick-borne disease diagnostics grew out of an experience no family wants to have. Her husband, Russ, developed neurological and psychiatric symptoms, including cognitive problems, anxiety and hallucinations. Despite Bell specifically requesting Lyme disease testing early in his illness, his initial test was negative and his diagnostic journey eventually led to an Alzheimer's disease diagnosis. Bell later documented her family's experience in her memoir, What Lurks in the Woods. Today, she brings her engineering background and personal experience together in an effort to improve the diagnostic tools available to clinicians and patients. From MIT & Duke to Galaxy Diagnostics Nicole Bell is CEO of Galaxy Diagnostics and an engineer with extensive experience in medical devices and diagnostics. She earned bachelor's and master's degrees in Materials Science and Engineering from MIT and a master's degree in Biomedical Engineering from Duke University. Before joining Galaxy, she worked in technology and medical-device development, including leadership roles involving diagnostic platforms and FDA submissions. Bell became CEO of Galaxy Diagnostics in 2024, bringing together her professional background in engineering and diagnostics with the lessons learned through her husband's illness. The State of Lyme Disease Research Bell is also the primary author of The State of Lyme Disease Research in the United States for the Center for Lyme Action. The paper examines gaps in Lyme disease research and outlines recommendations involving fundamental science, diagnostics, prevention, treatment, and research infrastructure. In this interview, Bell references one particularly important issue explored in that work: delays in Lyme disease diagnosis and treatment are associated with a greater risk of patients experiencing persistent symptoms. Better testing isn't simply about producing a more sophisticated laboratory report. It's about helping clinicians get patients appropriate answers earlier. Key Topics in This Episode Lyme disease testing, Lyme diagnostics, Nicole Bell, Galaxy Diagnostics, Borrelia testing, Bartonella testing, Babesia testing, Three B's, BBB Direct Detect, digital PCR, dPCR, PCR testing, antibody testing, antigen testing, direct detection, indirect testing, stealth pathogens, Lyme disease antibodies, coinfections, polymicrobial tick-borne disease, low-abundance infections, Bartonella culture enrichment, Babesia microti, Babesia duncani, Babesia odocoilei, Babesia divergens, chronic Lyme disease, diagnostic delays, and tick-borne disease research. About This LIVE from ILADS Interview This short-form conversation was recorded in person at the 2025 International Lyme and Associated Diseases Society Annual Scientific Conference, From Terrain to Treatment: Advances in Vector-Borne Illness, held October 9–12, 2025, in San Antonio, Texas. Because these interviews were recorded live at the conference, they have a different feel from Tick Boot Camp's traditional long-form virtual and studio conversations — shorter, focused, and surrounded by the activity of one of the world's major gatherings of Lyme and tick-borne disease clinicians, researchers, advocates, and innovators. Explore all Tick Boot Camp LIVE from ILADS interviews. More from Tick Boot Camp Hear more conversations with Lyme disease doctors and healthcare professionals about testing, diagnosis, treatment, and complex tick-borne illness. Explore the Tick Boot Camp Podcast for interviews with patients, doctors, researchers, advocates, and innovators working to improve understanding of Lyme disease and help people move toward recovery.

Novartis made the most likable pharma ad of the Super Bowl—Gronk, hammocks, "relax your tight end"—and won the Pharma Lions Grand Prix at Cannes for it. But when paid media is the only channel that legal can fully control, the ad quietly becomes your whole operating system, and everything it can't say gets handed to someone else.  In this month's PESO Model® Diagnostic, Gini Dietrich runs the full Novartis campaign through the PESO lens, names the regulated-industry trap, and lays out the fixes that survive a compliance review—at every size of organization. Take the PESO Model® Diagnostic: https://spinsucks.com/self-peso-diagnostic/PESO Model® Certification: https://spinsucks.com/peso-model-certification/Full article: https://spinsucks.com/communication/peso-model-diagnostic-novartis/

In today's episode, we welcomed Tracy I. George, MD, who provided a pathologist's perspective on the diagnosis and evolving management considerations for systemic mastocytosis. Dr George is president of the Innovation Business Unit and chief scientific officer at ARUP Laboratories and a professor of pathology at the Spencer Fox Eccles School of Medicine at the University of Utah in Salt Lake City.In the exclusive interview, Dr George highlighted the key hallmarks of systemic mastocytosis that can inform diagnosis, detailed how pathologists collaborate with other multidisciplinary experts to care for patients with systemic mastocytosis, and explained how agents such as avapritinib (Ayvakit) and bezuclastinib (CGT9486) are transforming patient care.

Medical Disclaimer: The information shared on This Week in HRV is for educational purposes only and is not intended as medical advice. Always consult a qualified healthcare professional before making changes to your health routine. This week on This Week in Heart Rate Variability, we cover six studies that together sketch the future of HRV science. Each one points in a distinct direction: a new metric for measuring rhythm organization across a large psychiatric population, a systematic content audit of consumer HRV apps, a rigorous benchmark of five noninvasive sensor technologies measured simultaneously in the same subjects, a new mathematical framework that challenges the stationarity assumption underlying conventional HRV analysis, a nonlinear dynamical study of group physiological coordination using attractor reconstruction and neural network clustering, and a deep learning system that extracts HRV from facial video alone to detect driver drowsiness at nearly ninety-five percent accuracy. What unites these studies is not a single topic but a shared direction: the field is expanding its metrics, scrutinizing its tools, rethinking its assumptions, and reaching toward applications that would have seemed impractical not long ago. 1. Heart rate fragmentation in psychiatry: across age stages and association with conventional heart rate variability PUBLICATION: Psychiatry Research: NeuroimagingAUTHORS: XinFan Zhang, AiMei Ye, Min Su, Hao Chai, YanYan Wei, YiYi Yang, YuXuan Xiong, Yin Cui, Dan Zhang, Xiong Jiao, HuiRu Cui, LiHua Xu, XiaoChen Tang, HaiChun Liu, MingLiang Ju, LingYun Zeng, ChunBo Li, LiYing Huang, Jin Gao, JiJun Wang, and TianHong Zhang KEY FINDING: Researchers analyzed resting three-minute electrocardiograms from 3,813 patients with schizophrenia, depressive disorder, anxiety disorder, or sleep disorder, ranging in age from 10 to 80 years, treated at the Shanghai Mental Health Center. The study derived both heart rate fragmentation indices—specifically the percentage of inflection points (PIP) and the related percentage of alternating segments (PAS)—alongside conventional HRV measures including RMSSD, SDNN, low-frequency power, and high-frequency power. Heart rate fragmentation increased systematically across age groups, while every conventional HRV index declined. That divergence is the central finding: aging appears to produce both less variability and less organized variability, and these are not the same thing. Partial Spearman correlations and multivariable linear regression confirmed that PIP retained independent associations with all conventional HRV metrics, even after adjusting for available covariates, with the strongest association observed for high-frequency power. Sex differences in fragmentation were confined to adolescence and early adulthood, with males showing higher PIP than females in those life stages, but these differences disappeared by middle and late adulthood. Diagnostic category had a statistically significant main effect on PIP, but the differences between diagnostic groups were modest and did not meaningfully interact with age. SIGNIFICANCE: Heart rate fragmentation asks a different question than conventional HRV metrics. While RMSSD and SDNN measure how much the intervals between heartbeats vary, fragmentation measures how organized that variability is. The consistent independent relationship between PIP and conventional HRV metrics suggests that fragmentation captures something about rhythm organization that amplitude-based measures do not fully account for. Because fragmentation can be computed from the same R-R interval data used in conventional HRV analysis, there is no additional measurement burden when adding it to existing protocols. Read th...

Tu as des offres incroyables et pourtant personne ne les voit

« J'aurais dû. » « Si seulement j'avais su. » Deux phrases courtes, mais qui portent le poids le plus lourd au monde : celui du regret.Regret de ne pas avoir osé, de ne pas avoir agi, de ne pas avoir tenté. On le masque souvent derrière de la prudence ou un besoin de réfléchir, mais la vérité est bien plus brute : c'est un manque de courage face à un système nerveux terrifié. On se rassure en se disant que ce n'est pas urgent, que l'on a le temps. Puis les secondes deviennent des heures, les années défilent, et l'on se réveille des décennies plus tard, le dos courbé sous le poids des rêves abandonnés.Dans cet épisode du Mindset Show, Jordan livre une réflexion poignante sur la valeur du temps, le piège de l'auto-sabotage et l'urgence de se refaire confiance. Il déconstruit cette manie de dire "je ne sais pas ce que je veux" pour révéler ce qu'elle cache vraiment : un manque de connaissance de soi, une faim de validation et une peur de s'écouter.Ce que tu refuses d'oser aujourd'hui deviendra tes regrets de demain. Vas-tu continuer de fuir ou décider de miser sur toi ?Au programme de cet épisode d'impact :L'anatomie du regret : Pourquoi « j'aurais dû » est l'aveu d'un manque de courage travesti en prudence.Le piège de la fausse ignorance : Pourquoi dire "je ne sais pas ce que je veux" signifie en réalité "je ne me connais pas et je ne me fais pas confiance".L'auto-trahison du quotidien : Le lien entre accepter des choses dont tu n'as pas envie et perdre la foi en ton propre potentiel.L'étincelle du passage à l'action : Pourquoi agir malgré le doute est le seul moyen d'honorer son humanité.Tu n'es pas là pour subir ou pour plaire. Tu es là pour écouter ta voix intérieure et construire la vie qui te revient.

Send Katie a Text Message!! If your interior design firm keeps running out of leads, your problem may have started months before your pipeline went quiet.In Part 3 of The Design Business Diagnostic, I'm diving into the second pillar of a healthy design firm: Predictable Marketing. This isn't about posting more on Instagram, going viral, or chasing vanity metrics. It's about creating a repeatable system that consistently puts your firm in front of the right people and creates enough qualified opportunities that your business isn't riding on whether one or two prospects say yes. In this episode, I'm talking about: Why your lead problem may have been created six months ago  The “feast, famine, freak out” cycle that keeps design firms scrambling for clients  Why promising prospects shouldn't determine whether you continue marketing  How to calculate how many qualified opportunities your firm actually needs  Why a healthy pipeline gives you more power to hold boundaries and choose better projects  The difference between marketing and selling  Why today's marketing activity creates tomorrow's pipeline  How to keep marketing when cash is tight without simply spending more money  Why relationships can be one of your strongest marketing advantages  Which marketing metrics matter more than likes, views, and follower counts  The simple pipeline exercise every design firm owner should do this week If you're constantly turning marketing on when you need clients and off when you get busy, the answer probably isn't another random marketing tactic. You need a system capable of creating the right opportunities consistently.If you're not sure whether Predictable Marketing is actually what's constraining your growth, book a complimentary 15-minute Business Diagnostic Call at FixMyDesignBiz.com. We'll look at what's happening across your business and identify what actually needs your attention next. Connect with KatieLinkedInBusiness Strategy Sessions for Interior Designers Free Resources for scaling your interior design firmWebsite

Es-tu réellement en train de construire ta vie… ou es-tu simplement en train de réagir à celle que tu as ?Beaucoup de gens pensent que subir sa vie signifie ne rien faire. Pourtant, on peut être extrêmement occupé, travailler dur chaque jour et avoir des objectifs, tout en restant spectateur de son propre destin. Subir commence de manière très subtile : le jour où l'on arrête de décider, où l'on transforme son quotidien en une succession de conditions (« quand j'aurai plus de temps », « quand j'aurai plus d'argent ») et où l'on attend que les circonstances changent d'elles-mêmes.Dans cet épisode du Mindset Show, Jordan décortique l'illusion de l'attente et rappelle une vérité fondamentale : tu ne peux pas contrôler tous les événements, mais tu contrôles totalement la façon dont tu y réponds. En t'apportant un cadre d'auto-évaluation concret, cet épisode t'invite à faire le deuil des excuses, à accepter le prix de la décision et à reprendre immédiatement les commandes de ton existence.Un conquérant ne demande pas quand les choses vont changer : il décide de ce qu'il va commencer à changer aujourd'hui.Au programme de cet épisode de réappropriation de son pouvoir :L'illusion de l'occupation : Pourquoi être débordé ne veut pas dire que tu diriges ta vie.Passer de la réaction à la responsabilité : La question exacte à te poser face à chaque difficulté pour récupérer immédiatement ton pouvoir d'action.Le coût caché de la décision : Pourquoi subir est parfois plus rassurant que décider (et comment briser cette paralysie).L'exercice du bilan immédiat : Un processus en 3 étapes à exécuter après l'épisode pour transformer une situation subie en action concrète.Ton prochain niveau ne commencera pas lorsque les circonstances deviendront parfaites, mais le jour où tu décideras d'agir malgré l'incertitude.

Is adult ADHD being over-diagnosed? A new survey of British doctors shows 7 in ten of the 829 GPs survey believed the disorder is over-diagnosed. They estimate more than 80% of patients they refer for assessment end up with a diagnosis. But a registered GP believes it's not the same in New Zealand. Dr John Cameron told Mike Hosking that based on overseas statistics and criteria from the Diagnostic and Statistical Manual of Mental Disorders, New Zealand is probably well under-diagnosing ADHD. LISTEN ABOVE See omnystudio.com/listener for privacy information.

La semaine fondamentale « de la mort » est maintenant derrière nous. Après le passage de l'ouragan, où en est le marché sur le plan technique ? Briefing fondamental et tour d'horizon technique cross-asset avec Vincent Ganne.

Journée mondiale d'Alzheimer : sensibilisation sur l'importance du diagnostic précoce et de l'accompagnement by TOPFM MAURITIUS

On réclame tous le changement, mais quand il frappe à la porte… on recule.Pourquoi est-il si difficile d'évoluer, même quand la situation actuelle ne nous convient plus ? La vérité est inconfortable : le changement n'est pas seulement une nouvelle étape, c'est une mort symbolique de l'ancien soi. C'est abandonner des repères rassurants pour plonger dans un vide que le cerveau associe immédiatement au danger.Dans cet épisode du Mindset Show, Jordan analyse la psychologie profonde du changement et explique pourquoi la peur que tu ressens n'est pas un manque de courage, mais un mécanisme de survie. Tu découvriras comment dépasser la paralysie de la zone de confort, apprivoiser le vide entre qui tu es et qui tu veux devenir, et faire le premier pas vers ta prochaine transformation.Ce n'est pas la peur du changement qui fait le plus mal… c'est le regret d'être resté la même personne dans 5 ans.Au programme de cet épisode :La neurobiologie de la résistance : Pourquoi ton cerveau préfère une souffrance connue à un futur incertain.Sécurité vs Liberté : Comment distinguer le doute légitime de la simple peur du vide.La mue identitaire : Pourquoi changer implique d'accepter de laisser mourir une ancienne version de soi.La décision intérieure : Pourquoi le vrai changement commence par un engagement envers soi-même plutôt que par des actions extérieures.Le changement ne s'attend pas : il se choisit.

durée : 00:05:06 - Les Matins de France Culture - par : Alexandre Morales - Le sang menstruel pourrait contenir des biomarqueurs de l'endométriose. Leur analyse en laboratoire permettra peut-être, dans quelques années, de faciliter le diagnostic de cette maladie qui touche près de 10 % des femmes. - invités : Camille Berthelot Chargée de recherche Inserm à l'institut Pasteur, directrice du groupe Génomique Fonctionnelle Comparative Vous aimez ce podcast ? Pour écouter tous les épisodes sans limite, rendez-vous sur Radio France

Get KAKISTOCRACY on Amazon: https://bit.ly/4hxg9Lh Synopsis Richard Hanania is back. His new book, Kakistocracy, argues that populism ends in rule by the worst people, and he and Noam spend an hour testing that against the news: why populism can win without being popular, whether the Iran war was worth the shot even if it fails, whether China would rather help us than fight us, and how the right built a media culture where Tucker Carlson can say Israel killed Charlie Kirk and the vice president shrugs. Then the hardest subject on the show: Nathan Cofnas and "race realism." Hanania explains why he thinks the taboo is universal and why Cofnas is wrong that breaking it defeats wokeness, and Noam tells two stories about kids the experts wrote off. Plus the Epstein email dump, diagnostic inflation, and why smart people believe in God, demons, and the supernatural. 0:00 Intro: Compliments 4:21 "Believe the media": defending the Times, what populism is, and "low human capital" 11:24 Is populism even popular? Mamdani, Trump's 30 percent, the AfD, and what populism costs 22:42 The Iran war argued with hindsight: Hormuz, the Houthis, "worth a shot," and China 35:00 Making things up: Tucker, Candace, Charlie Kirk, Ilhan Omar, and Father Coughlin 41:51 "Our guys lie less": Covid, the mulligan, gatekeepers, and what democracy is for 52:59 Race realism: Cofnas, Charles Murray, little Bernie Goetzes, and two kids the experts got wrong 68:02 Diagnostic inflation, labels, and why smart people are finding God

In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., president and CEO of Mayo Clinic Laboratories, to discuss seasonal vaccination planning and survey findings on laboratory industry growth. Later, Leslie Donato, Ph.D., a clinical chemist at Mayo Clinic, shares how an innovative testing panel is improving the diagnosis of bile acid malabsorption.Survey highlights laboratory growth strategies (00:29): Discover where laboratory leaders are investing, the challenges shaping the industry, and the strategies organizations are adopting to achieve sustainable growth.Seasonal viruses and vaccination planning (05:29): Discover how to learn more about vaccination options for viruses that typically surge during the fall and winter.Diagnostics for chronic diarrhea (07:43): Hear how a novel test is improving diagnosis and advancing understanding of bile acid malabsorption.ResourcesSurvey reveals four strategies for laboratory growthVaccine and immunization guidance from Mayo ClinicTesting Options for Patients with Chronic Diarrhea: A Focus on Bile Acid Malabsorption WebinarBile acid malabsorption: A patient-centered approach to diagnose a common cause of chronic diarrheaThe right testing for an underrecognized cause of chronic diarrhea

Get KAKISTOCRACY on Amazon: https://bit.ly/4hxg9Lh Synopsis Richard Hanania is back. His new book, Kakistocracy, argues that populism ends in rule by the worst people, and he and Noam spend an hour testing that against the news: why populism can win without being popular, whether the Iran war was worth the shot even if it fails, whether China would rather help us than fight us, and how the right built a media culture where Tucker Carlson can say Israel killed Charlie Kirk and the vice president shrugs. Then the hardest subject on the show: Nathan Cofnas and "race realism." Hanania explains why he thinks the taboo is universal and why Cofnas is wrong that breaking it defeats wokeness, and Noam tells two stories about kids the experts wrote off. Plus the Epstein email dump, diagnostic inflation, and why smart people believe in God, demons, and the supernatural. 0:00 Intro: Compliments 4:21 "Believe the media": defending the Times, what populism is, and "low human capital" 11:24 Is populism even popular? Mamdani, Trump's 30 percent, the AfD, and what populism costs 22:42 The Iran war argued with hindsight: Hormuz, the Houthis, "worth a shot," and China 35:00 Making things up: Tucker, Candace, Charlie Kirk, Ilhan Omar, and Father Coughlin 41:51 "Our guys lie less": Covid, the mulligan, gatekeepers, and what democracy is for 52:59 Race realism: Cofnas, Charles Murray, little Bernie Goetzes, and two kids the experts got wrong 68:02 Diagnostic inflation, labels, and why smart people are finding God

Send Katie a Text Message!! You can have a $500,000 interior design firm and be broke. You can have a million-dollar firm and still be broke. Revenue alone doesn't tell me whether I'm looking at a financially healthy company.Welcome to Part 2 of The Design Business Diagnostic. Last week, I introduced the five areas I look at when diagnosing the health of an established design firm. Now we're going deeper, starting with Financial Foundation.. This isn't about becoming an accountant. It's about understanding enough about your numbers to financially lead your company and make decisions from information rather than fear, assumptions, or whatever happens to be sitting in your checking account.In this episode: Why revenue alone doesn't tell you whether your design firm is healthy  How a financial problem gets misdiagnosed as a marketing, hiring, or growth problem  Why more revenue can actually magnify bad business economics  How to calculate what your company needs to produce every month  Why your salary belongs in the cost of running the business  How to evaluate profitability by service rather than revenue alone  Why profit and cash are not the same thing  How a 90-day cash forecast helps you make decisions before problems happen  What belongs on a Financial CEO Dashboard  The 10 questions every design firm owner should be able to answer  Why financial fluency is leadership—not bookkeeping If you can't answer every question in this episode, that's not a reason to panic. It's information. Now you know where to look.And if you're not sure whether Financial Foundation is actually the constraint in your business, that's why I created the Business Health Diagnostic. Book your complimentary 15-minute Business Diagnostic Call at FixMyDesignBiz.com.Connect with KatieLinkedInBusiness Strategy Sessions for Interior Designers Free Resources for scaling your interior design firmWebsite

Dans cet épisode, on aborde l'équilibre entre travailler dans l'ombre et te montrer sur la scène. Avec les énergies conceptuelle de la Nouvelle Lune en Vierge, on dit non à la procrastination et au perfectionnisme pour optimiser ton organisation au quotidien. Puis, la Pleine Lune

This podcast episode featured Celeste and Andria discussing Andria's recent mental health crisis and hospitalization due to a manic episode related to her bipolar disorder. Andria shared how she experienced symptoms including insomnia, rapid speech, and loss of control, but was initially dismissed by healthcare providers who told her she wasn't "crazy enough" for a bipolar diagnosis. After seven days of escalating symptoms, she was hospitalized where she received proper treatment and was prescribed mood stabilizers, which she described as life-changing. Celeste, who has bipolar disorder type 2, provided professional insights about diagnosis processes, medication management, and the importance of advocating for oneself in mental health treatment. They discussed how bipolar disorder can present with both manic and depressive episodes, the challenges of managing medication while bodybuilding, and the stigma surrounding mental health conditions. The conversation emphasized that proper treatment and medication can significantly improve quality of life, though recovery is a ongoing journey that requires patience and self-compassion. Bipolar Disorder Diagnosis Experience Andria shared her experience with a manic episode that led to hospitalization, describing how she initially sought help from doctors who dismissed her concerns about bipolar disorder. Celeste, who has bipolar disorder herself, explained the differences between bipolar one and bipolar two, noting that Andria's experience with a full manic episode fits the diagnosis of bipolar one. Celeste also shared her own experience of how starting antidepressant medication triggered her hypomanic symptoms, which led to her bipolar diagnosis. Healthcare System Access Challenges Andria discussed feeling let down by the healthcare system when she was unable to get timely psychiatric care despite experiencing manic episodes and seeking help from doctors. She explained that while she received a psychiatric referral, she faced a 90-day wait time for appointments, which proved too late as she had already had a manic episode. Andria noted that being on a mood stabilizer has been life-changing for her, and she is now focusing on stabilizing other aspects of her life to address her mental health needs. Bipolar Disorder Experience Sharing Celeste and Andria discussed their experiences with bipolar disorder, sharing how they initially struggled to recognize and seek help for their condition due to societal misconceptions about how someone with bipolar should behave. Andria emphasized that bipolar is more common than people realize and can lead to brain damage and other serious health issues. Both women described how they had to recalibrate their motivation and approach to life after experiencing the negative effects of untreated bipolar, with Celeste noting that learning about family history helped her recognize the genetic component of the disorder and seek proper treatment. Bipolar Disorder Diagnosis Approaches Andria shared her experience of struggling with bipolar disorder from ages 18 to 23, describing how she "white knuckled" through manic episodes by telling herself she could manage the next day, but eventually needed hospitalization. Celeste discussed therapeutic approaches to diagnosis, explaining that therapists often start with the "least restrictive" diagnosis that allows for broad treatment options before narrowing down specific conditions. Celeste emphasized that diagnoses should focus on treatment rather than identity, noting that the Diagnostic and Statistical Manual (DSM) criteria can sometimes prioritize statistics over individual symptoms and experiences. Mental Health Advocacy Discussion Celeste and Andria discussed the importance of advocating for oneself in mental health care, emphasizing that diagnoses can take time and encouraging individuals to persist in seeking appropriate treatment. Andria shared her personal experience with PTSD and depression, highlighting how she initially attributed symptoms to her existing diagnoses without seeking help from a psychiatrist. Both speakers stressed the value of seeking higher-level care, getting second opinions, and recognizing when additional support is needed, with Celeste noting that there is no shame in struggling with mental health challenges in today's demanding world. Bodybuilding Lifestyle and Mental Health Celeste and Andria discussed the importance of evaluating the sustainability of a bodybuilding lifestyle and addressing mental health challenges, including the impact of diagnoses and medication. Andria emphasized the value of seeking support, being vulnerable, and considering second opinions when dealing with health professionals. Celeste shared her experience with medication and its side effects, highlighting the need for careful monitoring and open communication with healthcare providers. Mental Health in Bodybuilding Celeste and Andria discussed the challenges of managing mental health while pursuing competitive bodybuilding. Andria shared her personal experience with bipolar disorder, including struggles with medication side effects and the decision to withdraw from fall competitions to prioritize her health. They explored how mental health stigma can create barriers to seeking help, with Andria emphasizing the importance of taking practical steps toward treatment rather than dismissing symptoms as "dramatic." The conversation highlighted how mental health treatment can have unexpected positive effects, like improved digestion, while acknowledging that recovery is a ongoing journey. CONNECT WITH ANDRIA: https://www.instagram.com/andria.ifbbpro/ https://www.instagram.com/fitmodelnofilter/   CONNECT WITH CELESTE: Website:http://www.celestial.fit Instagram:https://www.instagram.com/celestial_fit/ All Links:http://www.celestial.fit/links.html

A l'occasion de Septembre en or, mois pour parler du cancer pédiatrique, nous repartageons le témoignage d'Amélie, maman de Léo et Tom et d'un petit 3e né après le décés de Léo.Le premier mai 2024, Amélie et Bastien vivent l'impensable pour des jeunes parentsLeur 2e fils Léo, atteint d'un cancer, décède à l'âge de 16 mois. Pendant 13 mois, Amélie s'est battue avec son mari pour accompagner Léo, dans son parcours de soin.Entre ses doutes sur la santé de son bébé, les débuts de vie difficile de Léo et son premier bébé d'à peine 18 mois, Tom, Amélie navigue à travers un postpartum difficile et rempli d'angoisse.Depuis quasiment le début, Amélie sait que quelque chose ne va pas avec Léo et pourtant le corps médical mettra de longues semaines avant de répondre à ses doutes.Quand l'annonce du cancer leur tombe dessus, Amélie et Bastien mettent leur vie entre parenthèses.Grâce aux dons de collègues mais aussi d'association, ils peuvent de manière plus sereine, se consacrer à la survie de leur bébé.Comment le couple traverse cette épreuve ? Comment on inclut son premier bébé dans cette aventure médicale ? Comment on survit tout simplement à la perte de son enfant ? Amélie dégage une force incroyable et une capacité d'analyse très fine pour expliquer l'épreuve qu'elle vient de traverser.Chaque année 2500 enfants sont diagnostiqués d'un cancer pédiatrique, Septembre en or est l'occasion pour nous de leur rendre hommage

Send Katie a Text Message!! What if the thing you're trying to fix in your interior design business isn't actually the problem?I've had designers tell me they need more clients when the real issue is profitability. I've had designers convinced they need another employee when their business doesn't have the systems, financial capacity, or leadership structure to support one. And I've seen designers try to fix their marketing when the offer underneath it isn't clear enough to market.That's why I'm changing the way I coach—and why I'm introducing The Design Business Diagnostic.In this episode: Why the problem making the most noise isn't always the root problem  Why I've moved away from solving business issues in isolation  The five areas I diagnose in an established interior design business Financial Foundation: understanding the economics underneath your revenue Predictable Marketing: creating consistent demand before you need it Human Capital: putting the right people into the right structure CEO Leadership: building a company that doesn't depend on you for everything Products & Offerings: creating clear, profitable services the business can deliver well  How weaknesses in one area create symptoms somewhere else  Why tactics only work when the business underneath them is ready  What we're covering throughout the next five episodes This is the beginning of The Design Business Diagnostic, a new series where we're going deeper into each of these five areas. I don't want you simply asking, Do I know this? I want you asking, Is this actually working in my business? That's the distinction Katie makes as she introduces the upcoming series. If you're already wondering which area is actually holding your business back, book your complimentary 15-minute Business Diagnostic Call at FixMyDesignBiz.com.Connect with KatieLinkedInBusiness Strategy Sessions for Interior Designers Free Resources for scaling your interior design firmWebsite

Dejan Nenov is the Founder of Luventix, an AI-powered diagnostic platform that uses machine learning to analyze metabolic data from urine samples to detect multiple diseases and health conditions.  This approach, inspired by the ability of dogs to detect cancer through smell, enables a single non-invasive test to screen for conditions across oncology, neurology, immunology, and other areas at a fraction of the cost of genetic sequencing or blood tests.  The platform has applications in precision medicine, patient stratification for clinical trials, and population-level health screening.     Dejan explains, "The origin story is actually quite fun. One of my two co-founders and I were sitting around his dining table after a day of skiing and watching TV, and we saw dogs smelling urine and sitting down when the urine was from a cancer patient. And so we started thinking, can we reproduce this with technology? And we looked at it and said, "Well, what does the dog's nose do?" And we said, "Well, it's identifying the molecules in the volatiles of the sample, the urine. That looks suspiciously like gas chromatography."   "And then what happens? Well, the dog's brain determines whether the sample is positive or negative. And that's a classifier, a classic classification problem based on a dataset. So we roll back a year or so, and my co-founder Martin did a study to explore whether he could build models to do what the dogs did, but consistently in a mechanistically repeatable fashion."   "We demonstrated that, yes, indeed, based on creating a digital twin of the patient's organism using metabolic data from a urine sample, we're able to train models that can determine whether a disease or condition is present from a urine sample. In the most general case, that's sort of a patient stratification technology." #Luventix #DigitalHealth #PrecisionMedicine #HealthTech #AIinHealthcare #PatientEmpowerment #HealthInnovation #FutureOfHealthcare #DiagnosticInnovation #HealthTechStartup #ConnectedHealth#HealthcareInnovation #AIinHealthcare #Diagnostics #CancerDetection #MedicalAI #ClinicalTrials #Metabolomics #FutureOfMedicine luventix.com  Listen to the podcast here

Dejan Nenov is the Founder of Luventix, an AI-powered diagnostic platform that uses machine learning to analyze metabolic data from urine samples to detect multiple diseases and health conditions.  This approach, inspired by the ability of dogs to detect cancer through smell, enables a single non-invasive test to screen for conditions across oncology, neurology, immunology, and other areas at a fraction of the cost of genetic sequencing or blood tests.  The platform has applications in precision medicine, patient stratification for clinical trials, and population-level health screening.     Dejan explains, "The origin story is actually quite fun. One of my two co-founders and I were sitting around his dining table after a day of skiing and watching TV, and we saw dogs smelling urine and sitting down when the urine was from a cancer patient. And so we started thinking, can we reproduce this with technology? And we looked at it and said, "Well, what does the dog's nose do?" And we said, "Well, it's identifying the molecules in the volatiles of the sample, the urine. That looks suspiciously like gas chromatography."   "And then what happens? Well, the dog's brain determines whether the sample is positive or negative. And that's a classifier, a classic classification problem based on a dataset. So we roll back a year or so, and my co-founder Martin did a study to explore whether he could build models to do what the dogs did, but consistently in a mechanistically repeatable fashion."   "We demonstrated that, yes, indeed, based on creating a digital twin of the patient's organism using metabolic data from a urine sample, we're able to train models that can determine whether a disease or condition is present from a urine sample. In the most general case, that's sort of a patient stratification technology." #Luventix #DigitalHealth #PrecisionMedicine #HealthTech #AIinHealthcare #PatientEmpowerment #HealthInnovation #FutureOfHealthcare #DiagnosticInnovation #HealthTechStartup #ConnectedHealth#HealthcareInnovation #AIinHealthcare #Diagnostics #CancerDetection #MedicalAI #ClinicalTrials #Metabolomics #FutureOfMedicine luventix.com Download the transcript here

Drs. Kittleson and Ghafourian discuss how to accurately diagnose ATTR-CM, emphasizing that the first step must always be a complete monoclonal protein screen to exclude AL amyloidosis before interpreting a PYP scan. They highlight common pitfalls with PYP imaging; the supportive (but not definitive) role of cardiac MRI; the need for routine TTR genotyping after diagnosis; and the importance of recognizing noncardiac clues to identify patients early enough to benefit from disease‑modifying therapies.

SEASON FIVE BEGINS with Bryan & Kristen tying up some loose ends from last season including tiebreaker votes for the Strange New Worlds season finale, "New Life and New Civilizations," and "The Way to Eden" from The Original Series; but also, announcing the recipient of a Lower Decks Blu-ray box set as a thanks for their poetry. Then, they recount their summer, as Trek Marry Kill ventured to San Diego to host a panel at Comic-Con International. At STLV, the Inglorious Treksperts announced the Top 60 episodes of Star Trek of all-time -- how many are episodes we've MARRIED? And finally, a preview of the season ahead. Check out the Inglorious Treksperts episode listing Star Trek's Top 60! Check out the Ship Full of Jerks Podcast wherever you get your podcasts! Check out Enterprisesplaining wherever you get your podcasts! Learn more about your ad choices. Visit megaphone.fm/adchoices

REDIFF - Franck a partagé son expérience d'errance médicale pendant 30 ans avant de recevoir un diagnostic correct de trouble bipolaire en 2019. Cette découverte a transformé sa vie grâce à un traitement au lithium, lui permettant de retrouver une vie normale et de s'engager à sensibiliser les autres sur la santé mentale. Chaque soir, en direct, Caroline Dublanche accueille les auditeurs pour 2h30 d'échanges et de confidences. Pour participer, contactez l'émission au 09 69 39 10 11 (prix d'un appel local) ou sur parlonsnous@rtl.fr.Hébergé par Audiomeans. Visitez audiomeans.fr/politique-de-confidentialite pour plus d'informations.

Ever wonder what happens when a sample is sent to UF's Diagnostic Laboratory? Dr.…

Ever wonder what happens when a sample is sent to UF's Diagnostic Laboratory? Dr. Michael Dark, clinical associate professor and director of CVM's veterinary diagnostic labs, takes listeners behind the...

The Diagnostic and Statistical Manual of Mental Disorders has a formal diagnosis for caffeine withdrawal.It does not have one for postpartum psychosis.That's where this episode starts, and it turns out to explain almost everything about the six weeks that followed. As I record this, the jury in Plymouth has told the judge for the second time in two days that it cannot agree on whether Lindsay Clancy was criminally responsible. Five weeks of trial. More than eighty witnesses. The judge has now read them the Tuey-Rodriguez charge, the last instruction he has, and under Massachusetts law he can't read it again without their consent. Twelve people who saw every exhibit can't get there. The internet got there in nine minutes. This episode is not about whether she's guilty. It's about the machine that spent August turning three dead children into content, and it hits everybody.The women who made this their entire personality: the pink shirts, the "Same, Lindsay" trend, a hundred and sixty-four thousand TikToks, twenty-five Etsy designs, a crowd cheering a defense attorney like he'd walked out of Selma, and a fifty-six-year-old woman arrested in a courthouse parking lot. And the men who decided the correct response to a psychiatric emergency was a constitutional amendment. A retired UFC champion who was calling to repeal the 19th two years before he'd ever heard her name. A podcaster on episode 1,825. A commentator who looked at a stranger holding her own baby and asked where CPS was. Also in here: Why parasocial defendant worship is a format and not a female pathology, and what ten thousand people mailing $290,000 to Luigi Mangione proves about that. The Andrea Yates conviction that got overturned because an expert witness testified about a Law & Order episode that had never been filmed. All 269 episodes were searched. It did not exist. Twenty-five years later, a major podcaster covering this case said out loud that he didn't need his story verified.The nine murder-suicides a week that nobody is holding a rally about, and why there is no federal database counting them. Three fathers who raised the exact defense Clancy is raising. Nobody proposed taking anyone's vote away. And the number that ends the argument: the UK has around 21 psychiatric units where a woman in this emergency is admitted with her baby. France has 15. The United States has four million births a year and zero. Six weeks of the loudest people in America screaming about dead children, and not one of them proposed a bed or a solution. Become a supporter of this podcast: https://www.spreaker.com/podcast/we-saw-the-devil-unfiltered-political-analysis--4433638/support.Website: http://www.wesawthedevil.comPatreon: http://www.patreon.com/wesawthedevilRobin's Instagram: http://www.instagram.com/robin_wstdTwitter: http://www.twitter.com/WeSawtheDevilInstagram: http://www.instagram.com/wesawthedevilpodcast.TikTok: tiktok.com/@wesawthedevilpolitics

The promise of precision medicine depends on more than scientific innovation. It also depends on whether eligible patients can be identified, tested and connected to the most appropriate treatment. In this episode of The Top Line, host Kelly Hogan is joined by Susanne Munksted, chief growth officer at Diaceutics, and Jordan Clark, chief customer officer, to discuss why many diagnostic-driven therapies still fail to reach their full potential. Drawing on findings from Diaceutics' practice gap studies, the conversation explores where patients are being lost across the diagnostic pathway and why improvements in testing have not always translated into better treatment decisions. The guests discuss increasing healthcare complexity, expanding biomarker requirements and the challenges clinicians face when making treatment decisions under time pressure.See omnystudio.com/listener for privacy information.

Description: Featuring a slide presentation and related discussion from Prof Ticiana Leal, including the following topics: ·      Incidence, pathophysiology and clinical presentation (0:00) ·      Diagnostic challenges and evaluation process (3:37) ·      Treatment modalities and therapeutic options (10:01) ·      Mechanistic effects and key clinical trial data for amifampridine (12:20) ·      Key takeaways and conclusions (17:32) CME information and select publications

Lindsay Clancy is currently on trial for killing her three children.Prosecutors say the murders were intentional, but her defense team says she was suffering from severe postpartum psychosis -- a condition that does not have a distinct diagnosis in the Diagnostic and Statistical Manual of Mental Disorders.That's the handbook used to identify mental health conditions, so patients often have a hard time getting proper care.The case has put a spotlight on maternal mental health and how its treated by the public and healthcare professionals. What does it reveal?WBUR's Deborah Becker contributed reporting to this episode.It was produced by Megan Lim and Karen Zamora, with audio engineering by Éowyn Fain, Hannah Gluvna and Ted Mebane. Our director is Jonas Adams.It was edited by Justine Kenin and Tinbete Ermyas.Our interim executive producer is Courtney Dorning.Support public media with NPR+ and enjoy perks for over 25 podcasts like this one. This show's perks include bonus episodes and sponsor-free listening. Learn more at plus.npr.org.See pcm.adswizz.com for information about our collection and use of personal data for sponsorship and to manage your podcast sponsorship preferences.NPR Privacy Policy

If you've done all the “right” things for your gut, eating clean, avoiding gluten, taking supplements, running labs, and still feel like your gut health stinks, this episode is for you. We're challenging the idea that your gut is something you need to “fix” and exploring why symptoms like bloating, constipation, diarrhea, and gas may actually be signals rather than signs that something is broken. We zoom out to look at the gut as part of a much bigger web involving the brain, nervous system, hormones, immune system, stress, sleep, and circadian rhythm, and we share simple strategies that can help support your body without adding another complicated protocol to your life. Our goal is to help you stop chasing symptoms, start listening to your body, and build resilience from the inside out.SHOW NOTES:0:38 Welcome to the show!3:03 Why your gut isn't broken6:09 Limbic Retraining8:48 Underlying stressors to the gut9:24 Spider web analogy11:15 Simple hack to sync your gut rhythms14:28 Overnight fasting15:32 Perimenopausal & bloated16:31 Gut Healing Framework18:11 Basic elimination foods19:02 Regulating the stress response19:28 Renee's gut story21:15 How to support digestion27:30 The many types of trauma 30:18 Food Therapy31:15 Repairing the gut lining & microbiome32:56 “Party in my stomach”35:02 Supplements for gut healing37:50 The acid reflux myth43:22 Supporting motility & bowel movements47:00 Diagnostic lab testing49:50 Triggers for leaky gut57:30 Allergies vs Intolerances vs Sensitivities1:01:29 Elimination Diet1:03:41 Can you over-optimize your gut?1:05:21 Recapping the frameworkRESOURCES:Fullscript Gut Supplements (must create an account to access)Biohacker Babes Gut Healing Framework E-book (FREE until Sept 14)Primal Trust - code: BIOHACKERBABES10FREE Nervous System Harmony e-bookBook: Food TherapyPodcast with Luis MojicaSupport this podcast at — https://redcircle.com/biohacker-babes-podcast/donationsAdvertising Inquiries: https://redcircle.com/brands

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/TUX865. CME/MOC/AAPA/IPCE credit will be available until August 25, 2027.Closing the Diagnostic Gap in Eosinophilic Esophagitis: Turning Emergency Visits Into Earlier Recognition In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an independent educational grant from Regeneron Pharmaceuticals, Inc and Sanofi.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/TUX865. CME/MOC/AAPA/IPCE credit will be available until August 25, 2027.Closing the Diagnostic Gap in Eosinophilic Esophagitis: Turning Emergency Visits Into Earlier Recognition In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an independent educational grant from Regeneron Pharmaceuticals, Inc and Sanofi.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/TUX865. CME/MOC/AAPA/IPCE credit will be available until August 25, 2027.Closing the Diagnostic Gap in Eosinophilic Esophagitis: Turning Emergency Visits Into Earlier Recognition In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an independent educational grant from Regeneron Pharmaceuticals, Inc and Sanofi.Disclosure information is available at the beginning of the video presentation.

Equitable access to healthcare, and more specifically diagnostic testing, remains elusive globally, negatively impacting the health and wellbeing of all people. A not-so-distant illustration was access to testing during the COVID-19 pandemic, when testing sites globally, including here in the United States, underserved the very populations who bore a disproportionate burden of COVID-19 cases and deaths. There is a tremendous opportunity for research on diagnostic access, as well as the epidemiology and diseases that impact underrepresented groups, in clinical microbiology. In 2026, JCM launched a new section, entitled "Diagnostic Access and Equity". In today's episode of Editors in Conversation, I'm joined by the Editor overseeing this section, Dr. Ellie Theel, and one of our editorial board members, Dr. Shawn Lockhart of the Centers for Disease Control and Prevention, to discuss diagnostic access, equity and what the clinical microbiology community is doing to move the needle on these issues. Guests: Elitza Theel, Ph.D., D(ABMM) Shawn Lockhart, Ph.D., D(ABMM) Links:  Remote regions, rapid recognition: performance and timeliness of BIOFIRE FilmArray BCID2 for diagnosing bloodstream infection in remote northern Australia This episode is brought to you by the Journal of Clinical Microbiology.  Visit asm.org/jcm to browse issues and/or submit a manuscript.  If you plan to publish in JCM, ASM Members get up to 50% off publishing fees. Visit asm.org/joinasm to sign up.

What if "I can't afford it," "Let me think about it," or "I need to ask my husband" weren't rejections at all? What if they were actually telling you exactly where your sales conversation went wrong? In this episode of the CEO Glow Show, Sheila Bella, founder of Pretty Rich Bosses, delivers a powerful reframe for beauty entrepreneurs and service providers: an objection isn't rejection. It's information. Instead of fearing objections or taking them personally, Sheila teaches you how to read them like a diagnostic report. Every objection can point to a step in the sales conversation where your potential client still needs more trust, value, clarity, certainty, or emotional investment before she feels ready to say yes. Sheila breaks down four of the most common objections beauty business owners hear and explains what may actually be happening underneath the words. "It's too expensive" can signal that you haven't built enough value. "Let me think about it" can reveal an unresolved gap in trust, pain, belief, or clarity. "I need to ask my husband" can point to missing certainty, while "Just send me some info" may mean you haven't created enough momentum or emotional investment. The goal isn't to become better at pressuring people into buying. It's to become better at building a sales conversation where your potential client has what she needs to make a confident decision. Once you stop treating objections like punches and start treating them like feedback, every sales conversation becomes an opportunity to improve. If you're a beauty entrepreneur who freezes when someone says, "That's too expensive," gets discouraged after hearing "I'll think about it," or struggles to confidently ask for the sale, this episode will completely change how you approach sales. 5 KEY POINTS 1. An objection is information, not rejection. Stop assuming an objection means the client is walking away. Sheila explains how objections can reveal exactly where the sales conversation needs more work. 2. "It's too expensive" can be a value problem. Before immediately lowering your price, look at whether you clearly communicated the value, transformation, pain being solved, and belief in your solution before revealing the investment. 3. "Let me think about it" means something may still feel unresolved. There may be a gap in trust, understanding, pain, belief, or clarity. Instead of getting defensive, get curious about what part of the conversation was left incomplete. 4. Stop being afraid of uncomfortable sales moments. The questions you're afraid to ask, the price reveal, and asking for the commitment are often the moments that expose what your sales process needs. Avoiding them can create pleasant conversations that never convert. 5. Every objection is free sales training. Instead of letting objections destroy your confidence, use them as data. Ask yourself, "What is she actually diagnosing? Which step did I skip?" Then use that information to improve the next conversation.

In our latest Science of Reading: Essentials episode, Susan Lambert, Ed.D., draws on expert voices from across the podcast to show how assessment can be one of the most exciting and empowering tools an educator has at their disposal. Featuring Jan Hasbrouck, Ph.D.; Stephanie Stollar, Ph.D.; Kate Winn; Kymyona Burk, Ed.D.; Kajal Patl Below; Gina Biancarosa, Ed.D.; and Melissa Farrall, Ph.D., this episode covers the three types of assessment every educator. needs—universal screening, diagnostic assessment, and progress monitoring—and how they work together; what the Oral Reading Fluency measure actually measures, why it matters, and how it's often misunderstood; and why assessing comprehension is so complex, and what teachers can do about it. Show notes: Check out all of our Science of Reading Essentials episodes.Sign up for our upcoming Assessment Webinar Series. Listen to Season 3 of Amplify's Beyond My Years podcast.Listen to the full episodes:The right assessment and the right data with Dr. Jan HasbrouckAssessment as your best friend, with Kate Winn and Stephanie Stollar, Ph.D.Language is always an asset, with Kajal Patel BelowUnderstanding assessment, with Melissa Farrall, Ph.D.Reimagining comprehension assessment, with Gina Biancarosa, Ed.D.A proactive response to the adolescent literacy crisis, with Kymyona Burk, Ed.D.Subscribe to Susan's new Science of Reading Substack.Join our Science of Reading community Facebook group.Connect with Susan Lambert.Quotes: “If you don't have a question about your students, you don't need to do more assessment. This should not be a compliance activity.” —Stephanie Stollar“We never want to do one iota, one second, one minute of extra assessment that we don't have to do unless it answers a key question that makes us better teachers.” —Jan Hasbrouck“About 90% of all reading challenges are due to difficulty recognizing the words.” —Melissa Farrall“We don't want more testing. We want the right kind of testing.” —Kymyona Burk“Once you ask a question, you can change what it is that someone has understood from what they read.” —Gina Biancarosa“When we love the kids, we want to do the best for them.” —Kate Winn“Ideally, kids would be assessed in their home language.” —Kajal Patel BelowTimestamps*:0:00 Science of Reading Essentials: Assessment3:00 Why educators have complicated feelings about assessment4:00 The three key questions every assessment should answer6:00 Universal screening8:00 Screening multilingual and English learners11:00 Diagnostic assessment12:00 Progress monitoring15:00 Why alignment across all three tools matters16:00 Teacher-administered and curriculum-based assessments18:00 Oral Reading Fluency (ORF): what it is and why it matters24:00 Why ORF is widely misunderstood28:00 The challenges of assessing comprehension38:00 Key takeaways and next steps*Timestamps are approximate

Highlights from the PER® CME activity "MET Alterations in NSCLC: Applying Diagnostic Advances and Targeted Therapies in a New Era of Treatment" — this podcast is not certified for credit. To participate in the full accredited activity and earn CME credit, use the link below.In this podcast, experts Jonathan Goldman, MD; Sanja Dacic, MD, PhD; Deborah Doroshow, MD, PhD; and Anne S. Tsao, MD, MBA, discuss diagnostic and treatment strategies for patients with MET-altered non–small cell lung cancer.Earn CME credit by completing the full accredited activity (available through September 19, 2026): https://www.gotoper.com/courses/met-alterations-in-nsclc-applying-diagnostic-advances-and-targeted-therapies-in-a-new-era-of-treatment-vdpvThis podcast, including the narration, was developed by PER® (Physicians' Education Resource®, LLC) editorial staff from the full online CME activity developed with these faculty. The narration was voiced by a PER staff member or by an AI tool. The podcast contains no product advertising. The full activity is supported by an educational grant from AbbVie, Inc.This content is for educational purposes only and is not a substitute for the independent clinical judgment of a health care professional. Faculty may discuss investigational or off-label uses; consult prescribing information for any products discussed.

A woman from Cleveland moved to Wisconsin, took the surname of Watts – a man serving five life sentences for killing his entire family – and filed to marry him. Women have been doing this for well over a century, and the ones who later walked away have almost never been asked why.BOOK: “They Told Me My Newborn Died – They Lied” by Darren Marlar: https://amzn.to/4ihvu3kEPISODE BLOG PAGE (includes sources): https://weirddarkness.com/wattsandlizzieREAD or DOWNLOAD the full transcript of this episode: https://weirddarkness.tiny.us/yzmw3jdnThis episode includes references to suicide and to the deaths of children. If you are struggling, you are not alone, and help is available. https://WeirdDarkness.com/HOPE is a free directory of mental health resources, organized by country, for anyone anywhere in the world who needs somebody to talk to. And if you're in the United States or Canada, you can get immediate help over the phone by dialing 988.FEATURED STORIES IN THIS EPISODE: Eight years after Chris Watts strangled his pregnant wife and smothered their two daughters, a woman from Cleveland has moved to Wisconsin, started signing his surname, and filed paperwork that now sits on a prison warden's desk. And Chris Watts is not the only man in permanent lockup who is seeking matrimony. Later, we'll look at the women who build relationships with men who will die behind bars, and what draws them in.CHAPTERS & TIME STAMPS (All Times Approximate)…00:00:00.000 = The Foreboding00:01:51.635 = Show Open00:03:19.353 = Ten Seconds At Dodge Correctional00:20:26.768 = Shannan, Bella, Celeste and Nico ***00:48:21.294 = He Will Write Back ***01:04:25.333 = Dead In All Respects ***01:24:35.204 = Nobody Counts Any Of This ***01:29:55.177 = Show Close*** = Begins immediately after inserted ad breakLISTEN ON PODCAST APPS: Look for this podcast on Apple Podcasts, Spotify, iHeart Radio, Amazon Music, Pandora, TuneIn Radio, and other podcast apps. Get a list of free listening apps here: https://weirddarkness.com/wdapps*No AI Voices Are Used In The Narration Of This Podcast*WeirdDarkness® is a registered trademark. Copyright ©2026, Weird Darkness.Originally aired: August 19, 2026This episode of Weird Darkness covers the marriage application Chris Watts filed from a Wisconsin prison eight years after murdering his pregnant wife and their two young daughters, and the long record of women who write to, visit and marry men who will never get out.It opens at Dodge Correctional Institution in Waupun, Wisconsin, where an inmate may touch a visitor twice, once at the start of a visit and once at the end, an embrace reporting puts at roughly ten seconds. On August 12th, 2026 the Daily Mail reported that Chris Watts, 41, and a 39-year-old Cleveland realtor named Lizzie Henderson had applied to marry inside the Wisconsin prison system. Lizzie had moved from Ohio to Wisconsin with her mother, filed a sealed petition for a confidential name change on September 12th, 2025, and appeared in prison visitor logs roughly twenty times during 2025, plus a visit on Christmas Day of 2024. Wisconsin handles these requests under policy 309.00.06, PIOC Marriages, which routes the application through a marriage coordinator and leaves the decision with the warden. No ceremony or license has been documented, and Watts has no projected release date.From there the episode goes back to the family. The Watts family doorbell camera recorded Shanann Watts arriving home at 1:48 in the morning on August 13th, 2018 at 2825 Saratoga Trail in Frederick, Colorado. She was 34 and fifteen weeks pregnant with a son the couple had named Nico, raising daughters Bella, four, and Celeste, three, and selling Thrive for Le-Vel while her husband worked for Anadarko Petroleum and carried on an affair with co-worker Nichol Kessinger. Watts failed a polygraph administered by Colorado Bureau of Investigation agent Tammy Lee, blamed Shanann for the girls' deaths, then retracted it. A drone over an Anadarko site called CERVI 319 found Shanann in a shallow grave and both girls submerged in crude oil inside storage tanks with eight-inch hatches. Judge Marcelo Kopcow sentenced him on November 19th, 2018 to five life sentences plus 84 years. In a February 2019 interview at Waupun, Watts described smothering Celeste in his truck while Bella sat beside her, and hearing Bella's last two words, "Daddy, no!", every time he closes his eyes.The second half opens in the autumn of 1921, when French railways ran extra trains to Versailles for the trial of Henri Désiré Landru, a furniture dealer who placed lonely-hearts advertisements in Paris newspapers and murdered eleven people. Women mailed him proposals of marriage while he awaited the guillotine. The modern version runs through Meet-An-Inmate, launched in 1998, and WriteAPrisoner, founded by Adam Lovell in 2000, which post profiles written on paper because American prisons allow no internet access; Susan Smith drew more than six thousand letters before pulling her listing in 2003. Hybristophilia, the term journalists reach for, was coined by sexologist John Money in 1986 and has never appeared in the Diagnostic and Statistical Manual. Sheila Isenberg's Women Who Love Men Who Kill, forensic psychologist Katherine Ramsland's "perfect boyfriend" model, and sociologist Megan Comfort's San Quentin fieldwork in Doing Time Together supply what the women themselves say they are getting.Two 2025 studies found that actively seeking out romanticizing TikTok content correlated with attraction while passive exposure predicted nothing. The risk is documented in the killings of Regina Capobianco and John Mann by her pen pal Thomas Knuff in Parma Heights, Ohio, and in the strangling deaths of Stephanie Dowells and Tania Thomas during family visits at Mule Creek State Prison. The marriages run from Nina Van Zandt, who married Haymarket defendant August Spies by proxy in 1887 and may have married an innocent man, through Ted Bundy and Carole Ann Boone, Doreen Lioy and Richard Ramirez at San Quentin, the Twinkie that served as Erik Menendez and Tammi Saccoman's wedding cake, and James Whitehouse, who wrote to Susan Atkins in 1985 and went on to Harvard Law School to serve as her attorney. All of it rests on Turner v. Safley, the 1987 Supreme Court decision in which Justice Sandra Day O'Connor noted that most inmates are eventually released, leaving the man who never will be an untested case. Rhode Island's 1909 civil death statute declared lifers "dead in all respects", and Britain barred whole-life prisoners from marrying in 2024 after Milly Dowler's murderer Levi Bellfield was granted permission.The episode closes on the women who leave, absent from every study in the field. Lynn Hartman ended her engagement to Steven Avery in October of 2016 and wrote that she had been fooled by the Netflix documentary. Paula Williamson married Charles Bronson at HMP Wakefield in November of 2017, had it annulled in 2019, and died that July at thirty-eight. Anna Eriksson divorced Lyle Menendez in 2001 and still argues for his release. No agency counts prison marriages, and every figure circulating online is unsourced. Chris Watts belongs to a long file rather than a new one, having received his first letters from strangers within weeks of his December 2018 sentencing, before he had written a word to any of them.LIKE WHAT YOU'RE HEARING? WEIRD DARKNESS has new episodes 7 DAYS A WEEK! Listen FREE wherever you get podcasts or visit WeirdDarkness.com/Listen • Paranormal • True Crime • Ghosts • UFOs • Cryptids • Unexplained • Want even more? Become an OFFICIAL WEIRDO for commercial-free episodes, bonus episodes, weeknight live chats, audiobooks & more at WeirdDarkness.com/OFFICIAL

For years, doctors told this pediatrician her pain was fibromyalgia and depression. It was quietly starving her aorta. Victoria Rundus is a board-certified pediatrician who spent four years being misdiagnosed before an ER physician finally listened to her abdomen and heard what everyone else had missed. This episode is based on her article "Diagnostic bias almost cost me my life," published on KevinMD. You will hear how a single label can close the door on everything else, both for the physician treating you and for the patient who starts writing off new symptoms as just the old diagnosis. She explains why the physical exam still matters when labs come back normal, why she felt she was not being heard, and why curiosity and humility belong next to medical knowledge, not beneath it. We usually see horses, but the zebras are real. Press play to hear how a diagnosis can close a door that should stay open, and what it takes to keep looking. Partner with me on the KevinMD platform. With over three million monthly readers and half a million social media followers, I give you direct access to the doctors and patients who matter most. Whether you need a sponsored article, email campaign, video interview, or a spot right here on the podcast, I offer the trusted space your brand deserves to be heard. Let's work together to tell your story. PARTNER WITH KEVINMD → https://kevinmd.com/influencer SUBSCRIBE TO THE PODCAST → https://www.kevinmd.com/podcast

Duolingo built the internet's favorite brand on rented land—the best shared media engine on the planet, run through one green owl on platforms it doesn't control. In this month's PESO Model® Diagnostic, Gini Dietrich looks at what the legend leaves out: an owned media record too thin to defend the brand when the 2025 "AI-first" backlash hit. You'll learn why Duo's chaos is actually disciplined character work, why AI engines ignore your funniest channel and cite your machine-readable record instead, and the three fixes that apply to any brand being told to "just go viral." Read the full article: https://spinsucks.com/communication/duolingo-peso-model-diagnostic/ Links: Take the free PESO Model® Diagnostic: https://spinsucks.com/self-peso-diagnostic/ PESO Model® Certification: https://spinsucks.com/peso-model-certification/  The series so far: Budweiser, Liquid Death, Peppa Pig, and HubSpot at spinsucks.com

This week on the show I share a diagnosis on a 2007 GMC Yukon where the A/C doesn't work and seems to max out the high side pressure before cutting off at park and driving down the road. Multiple parts have been replaced including the compressor, condenser, orifice tube, and the accumulator. Listen to find out the cause!Website- https://autodiagpodcast.com/Facebook Group- https://www.facebook.com/groups/223994012068320/YouTube- https://www.youtube.com/@automotivediagnosticpodcas8832Email- STmobilediag@gmail.comPlease make sure to check out our sponsors!SJ Auto Solutions- https://sjautosolutions.com/Automotive Seminars- https://automotiveseminars.com/L1 Automotive Training- https://www.l1training.com/Autorescue tools- https://autorescuetools.com/