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The Lancet Gastroenterology & Hepatology is a monthly journal that considers original research, reviews, and personal views in gastroenterology and hepatology from around the world. In the monthly podcasts, editors of the journal discuss highlights of the current issue.

The Lancet Gastroenterology & Hepatology


    • Apr 10, 2025 LATEST EPISODE
    • monthly NEW EPISODES
    • 13m AVG DURATION
    • 87 EPISODES


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    Latest episodes from Listen to The Lancet Gastroenterology & Hepatology

    In conversation with... Salvatore Piano

    Play Episode Listen Later Apr 10, 2025 19:05


    How does acute kidney injury presentation and management differ globally for patients hospitalised with cirrhosis? We spoke to Salvatore Piano, corresponding author of the landmark International Club of Ascites GLOBAL AKI study, about new data on regional variations in severity, phenotype, treatment, and outcomes across 5 continents.

    conversations piano international club
    In conversation with... John Chia

    Play Episode Listen Later Mar 6, 2025 13:29


    John Chia discusses the results of the ASCOLT trial, which explored the effect of aspirin after completion of standard adjuvant therapy for patients with colorectal cancer.

    In conversation with... Hannes Hagström

    Play Episode Listen Later Jan 11, 2025 21:23


    Hannes Hagström discusses a study investigating the feasibility of screening for advanced liver fibrosis alongside retina scanning in people with type 2 diabetes.

    In conversation with... Peter De Cruz

    Play Episode Listen Later Nov 6, 2024 14:42


    Peter De Cruz (University of Melbourne) discusses the PREDICT-UC trial of intensified versus standard dose infliximab induction therapy for steroid-refractory acute severe ulcerative colitis.

    In conversation with... Shahida Din and Beatriz Gros

    Play Episode Listen Later Nov 1, 2024 34:15


    Shahida Din (Western General Hospital, Edinburgh) and Beatriz Gros (Reina Sofía University Hospital, Cordoba) discuss two new papers on the harms associated with receiving placebo in induction and maintenance trials of biological therapies and small molecules in inflammatory bowel disease.

    In conversation with... Arndt Vogel

    Play Episode Listen Later Jul 31, 2024 18:31


    Arndt Vogel (Toronto General Hospital) discusses the NALIRICC trial of nanoliposomal irinotecan added to fluorouracil plus leucovorin in patients with cholangiocarcinoma and gallbladder carcinoma previously treated with gemcitabine-based therapies.

    conversations arndt vogel
    In conversation with... Sanna Nybacka and Magnus Simrén

    Play Episode Listen Later May 18, 2024 23:16


    Sanna Nybacka and Magnus Simrén (University of Gothenburg) discuss the CARIBS randomised controlled trial of a low FODMAP diet versus a low-carbohydrate diet versus pharmacological treatment in IBS.

    In conversation with... Nuru Noor

    Play Episode Listen Later May 9, 2024 19:55


    Nuru Noor (University of Cambridge) discusses the PROFILE trial of biomarker-stratified treatment strategies in people with newly diagnosed Crohn's disease.

    In conversation with... Mads Israelsen

    Play Episode Listen Later Mar 12, 2024 16:39


    Mads Israelsen (Odense University Hospital) discusses a study to validate the new nomenclature of steatotic liver disease in patients with a history of excessive alcohol intake.

    In conversation with... Louise Dye

    Play Episode Listen Later Mar 1, 2024 23:19


    Louise Dye (University of Leeds) discusses a trial exploring the role of expectancy and gluten ingestion on symptoms in people with non-coeliac gluten sensitivity.

    In conversation with... Tzu-Chan Hong

    Play Episode Listen Later Dec 20, 2023 14:40


    Tzu-Chan Hong (National Taiwan University Cancer Centre) discusses a systematic review and meta-analysis on primary antibiotic resistance of Helicobacter pylori between 1990 and 2022 in the Asia-Pacific region.

    In conversation with... Sarah Moen

    Play Episode Listen Later Nov 28, 2023 14:45


    Sarah Moen (Erasmus University Medical Center) discusses a retrospective cohort study examining the risk of metachronous colorectal cancer after partial or extensive colectomy in carriers of different pathogenic Lynch syndrome variants.

    In conversation with... Anna Emilie Kann

    Play Episode Listen Later Oct 14, 2023 16:19


    Anna Emilie Kann (Zealand University Hospital, Denmark) discusses a population-based study done in Denmark exploring the causes of mortality in patients with alcohol-related liver disease.

    In conversation with... Robert Krouse

    Play Episode Listen Later Sep 13, 2023 16:31


    Robert Krouse (University of Pennsylvania) discusses the pragmatic S1316 trial of surgical versus non-surgical management for patients with malignant small bowel obstruction.

    In conversation with... Marc Rothenberg

    Play Episode Listen Later Aug 10, 2023 14:29


    Marc Rothenberg (University of Cincinnati College of Medicine) discusses a new trial assessing the efficacy and safety of benralizumab in patients with eosinophilic gastritis, and how the surprising findings might change our understanding of eosinophilic gastrointestinal diseases.

    In conversation with... Jasmohan Bajaj

    Play Episode Listen Later Jun 7, 2023 12:48


    Jasmohan Bajaj (Virginia Commonwealth University and Central Virginia Veterans Healthcare System, Richmond, VA, USA), on behalf of the CLEARED Consortium, discusses a prospective observational cohort study examining global disparities in mortality and liver transplantation in hospitalised patients with cirrhosis.

    In conversation with... Adelina Artenie

    Play Episode Listen Later May 11, 2023 17:15


    Adelina Artenie (University of Bristol, UK) discusses a systematic review and meta-analysis exploring the incidence of HIV and HCV among people who inject drugs, and associations with age and sex or gender.

    In conversation with... Johan Burisch

    Play Episode Listen Later Apr 13, 2023 20:00


    Johan Burisch (Copenhagen University Hospital, Denmark) discusses the findings and recommendations of The Lancet Gastroenterology & Hepatology Commission on the cost of inflammatory bowel disease in high-income settings.

    In conversation with... Edouard Louis

    Play Episode Listen Later Feb 9, 2023 21:30


    Edouard Louis (University Hospital CHU of Liège) discusses the SPARE randomised controlled trial of infliximab or concomitant immunosuppressant withdrawal in patients with Crohn's disease.

    In conversation with... Paula Ghaneh

    Play Episode Listen Later Jan 24, 2023 20:20


    Paula Ghaneh (University of Liverpool) discusses the ESPAC5 randomised controlled trial of short-course neoadjuvant therapy compared with immediate surgery for patients with borderline resectable pancreatic ductal adenocarcinoma.

    In conversation with... Dan Turner

    Play Episode Listen Later Jan 7, 2023 14:51


    Dan Turner (Shaare Zedek Medical Center) discusses the VEDOKIDS study on the safety, effectiveness, and dosing of vedolizumab in children with IBD.

    In conversation with... Simon Baunwall

    Play Episode Listen Later Nov 10, 2022 15:21


    Simon Baunwall (Aarhus University Hospital) discusses the EarlyFMT trial, a randomized placebo-controlled trial of faecal microbiota transplantation for first or second Clostridioides difficile infection.

    In conversation with... James Alexander

    Play Episode Listen Later Oct 6, 2022 13:48


    James Alexander (Imperial College London) discusses the latest findings from the VIP case-control study, which is investigating COVID-19 vaccine immune responses in immunosuppressed patients with inflammatory bowel disease.

    Filip Knop on liraglutide for bile acid diarrhoea

    Play Episode Listen Later Sep 8, 2022 15:02


    Filip Knop (University of Copenhagen) discusses a trial of liraglutide versus colesevelam for the treatment of bile acid diarrhoea.

    In conversation with... Edward Kim

    Play Episode Listen Later Aug 5, 2022 14:06


    Edward Kim (Icahn School of Medicine at Mount Sinai) discusses the single-arm RASER study of radiation segmentectomy for patients with unresectable very early to early stage hepatocellular carcinoma.

    In conversation with... Joep Ijspeert

    Play Episode Listen Later Jul 6, 2022 10:26


    Joep Ijspeert (Amsterdam University Medical Center) discusses a population-based study exploring the detection of proximal serrated polyps and interval post-colonoscopy colorectal cancer risk.

    In conversation with... Elise Meima-van Praag

    Play Episode Listen Later Jun 15, 2022 9:50


    Elise Meima-van Praag (Amsterdam University Medical Centre) discusses the PISA-II trial, investigating short-term anti-TNF therapy with surgical closure versus anti-TNF therapy for perianal fistulas in Crohn's disease.

    In conversation with... Juan Pablo Arab

    Play Episode Listen Later May 10, 2022 17:06


    Juan Pablo Arab (Catholic University of Chile) discusses the current burden of NAFLD and the landscape of public health policies related to the disease in the Americas.

    In conversation with... Sarah Blach

    Play Episode Listen Later Apr 7, 2022 8:57


    Sarah Blach (CDA Foundation) summarises the latest analysis of global hepatitis C virus epidemiology and cascade of care by the Polaris Observatory HCV Collaborators.

    In conversation with... Sunil Solomon

    Play Episode Listen Later Mar 23, 2022 15:02


    Sunil Solomon (Johns Hopkins University) discusses a study of a minimal monitoring approach for treating patients with hepatitis C virus infection.

    In conversation with... Rupert Leong

    Play Episode Listen Later Mar 12, 2022 13:43


    Rupert Leong (University of Sydney) discusses a new double-blind, randomised, placebo-controlled trial of oral faecal microbiota transplantation for patients with active ulcerative colitis.

    In conversation with... Swati Patel

    Play Episode Listen Later Feb 10, 2022 19:27


    Swati Patel (University of Colorado Anschutz Medical Center) discusses the epidemiology, clinical features, biology, risk factors, and opportunities for prevention and detection of early-onset colorectal cancers.

    In conversation with... Emilie Breekveldt

    Play Episode Listen Later Dec 10, 2021 9:39


    Emilie Breekveldt (Erasmus Medical Center, Netherlands) discusses a new analysis of the faecal immunochemical testing-based colorectal screening programme in the Netherlands.

    In conversation with... Wendy Spearman

    Play Episode Listen Later Nov 11, 2021 22:34


    Wendy Spearman (University of Cape Town) discusses a Series on the emergence of non-alcoholic fatty liver disease in Sub-Saharan Africa and the challenges it presents.

    In conversation with... Tim Vanuytsel

    Play Episode Listen Later Sep 9, 2021 7:02


    Tim Vanuytsel (University of Leuven) discusses a new trial of spore-forming probiotics in functional dyspepsia.

    In conversation with... Raymond Henderson

    Play Episode Listen Later Aug 12, 2021 11:20


    Raymond Henderson (Queen's University Belfast) discusses a new analysis of the economic burden of colorectal cancer in Europe.

    In conversation with... Sigurður Ólafsson

    Play Episode Listen Later Jun 22, 2021 13:09


    Sigurður Ólafsson (Landspitali University Hospital) discusses newly published results from the nationwide programme to eliminate hepatitis C virus in Iceland.

    In conversation with… Caroline Ovadia

    Play Episode Listen Later Jun 3, 2021 12:25


    Caroline Ovadia (King's College London) discusses an individual participant data meta-analysis on the treatment of intrahepatic cholestasis of pregnancy with ursodeoxycholic acid.

    In Conversation with… Matthew Akiyama

    Play Episode Listen Later Apr 12, 2021 7:06


    Matthew Akiyama (Montefiore Medical Center and Albert Einstein College of Medicine, USA) discusses a Review on hepatitis C elimination among people incarcerated in prisons.

    In Conversation with… Monika Sarkar

    Play Episode Listen Later Mar 19, 2021 8:15


    Monika Sarkar (University of California San Francisco, USA) discusses her Comment on reproductive health in women with chronic liver disease.

    Colorectal cancer risk in patients with Crohn’s disease

    Play Episode Listen Later Mar 12, 2020 7:04


    Ola Olén discusses the assesment of colorectal cancer risk in patients with Crohn's disease.

    Anti-TNFα therapy and risk of cancer in patients with immune-mediated diseases

    Play Episode Listen Later Jan 31, 2020 4:08


    Dr Akbar Waljee discusses findings from a cohort study investigating the risk of cancer recurrence or a new primary cancer in patients with IBD, rheumatoid arthritis, or psoriasis who received anti-TNFα therapy.

    Liver damage in young adults

    Play Episode Listen Later Jan 17, 2020 7:21


    Dr Kushala Abeysekara discusses research looking at the prevalence of non-alcoholic fatty liver disease in young adults in England.

    Treatments for IBS

    Play Episode Listen Later Jan 14, 2020 8:20


    Professor Alexander Ford discusses a meta analysis comparing different traditional treatments for irritable bowel syndrome.

    Statins and decompensated cirrhosis

    Play Episode Listen Later Nov 27, 2019 6:39


    Dr. Elisa Pose discusses the potential beneficial effects of statins on the treatment of patients with decompensated cirrhosis

    Global burden of pancreatic cancer and colorectal cancer

    Play Episode Listen Later Nov 4, 2019 14:44


    Mohsen Naghavi describes the key findings from two new Global Burden of Disease studies investigating the global burden of pancreatic cancer and colorectal cancer.

    Paediatric inflammatory bowel disease

    Play Episode Listen Later Sep 12, 2019 7:46


    Viktor Wintzell joins The Lancet Gastroenterology & Hepatology to discuss the risk of serious infection after use of tumour necrosis factor-α inhibitors in children with inflammatory bowel disease.

    Transplanting hepatitis C-infected hearts

    Play Episode Listen Later Aug 28, 2019 6:38


    Prof Raymond Chung discusses new research in transplantation of HCV-infected hearts.

    Primary anastomosis as a treatment for diverticulitis

    Play Episode Listen Later Jul 31, 2019 8:29


    Daniel Lambrichts joins The Lancet Gastroenterology & Hepatology to discuss different treatments for diverticulitis.

    Faecal microbiota transplantation in IBS

    Play Episode Listen Later Jul 30, 2019 7:18


    Dr Olga Aroniaidis discusses the results of a newly published trial of FMT to treat IBS.

    Treating faecal incontinence in women

    Play Episode Listen Later Jul 17, 2019 8:43


    Dr Eric Jelovsek discusses new research into the treatment of this important and often overlooked condition.

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