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Rheumatoid arthritis is not just a joint disease but a disorder of accelerated immune aging, with your immune system acting decades older than your actual age People with early joint pain already show reduced production of fresh immune cells and higher levels of inflammation, years before arthritis is formally diagnosed Research shows rheumatoid arthritis patients in their 40s and 50s have immune systems resembling much older adults, with DNA damage and exhausted immune cells Old, worn-out immune cells called senescent cells build up in rheumatoid arthritis, driving joint damage and weakening your body's ability to fight infections Practical steps like eating spermidine-rich foods, removing senescent cells, lowering inflammation, improving sleep and stress control, and supporting mitochondrial energy help keep your immune system younger and more resilient
AI is transforming medicine at a speed never seen before. In this episode, you'll discover how digital twins and artificial intelligence will revolutionize drug discovery, eliminate human trials, and personalize your biology for longevity and high performance. Host Dave Asprey breaks down how AI can now simulate virtual cells and tissues, running clinical experiments in minutes instead of years to create truly individualized medicine. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Dr. Derya Unutmaz is a world-renowned immunologist, systems biologist, and professor at The Jackson Laboratory. With more than 150 scientific papers, he's a leading expert in immune system research and one of the first scientists to pioneer the concept of digital twins for biology. His groundbreaking work uses AI to model how immunity, metabolism, and aging interact—creating new possibilities for personalized medicine, disease prevention, and lifespan extension. Host Dave Asprey and Dr. Unutmaz reveal how AGI will soon outperform doctors, accelerate functional medicine, and optimize human biology far beyond today's standards. You'll learn how the immune system drives inflammation and aging, how to re-engineer it for resilience, and why compounds like GLP-1 and metformin may add years to your life. You'll Learn: • How digital twins will end human drug testing • Why AGI could replace doctors and computer jobs within five years • How AI models immune function, metabolism, and aging • The role of mitochondria and inflammation in longevity • How GLP-1 drugs and metformin extend lifespan • What continuous biological monitoring means for health tracking • How AI is transforming functional medicine and personalized care • Why NAD and energy metabolism are key to human performance They explore how artificial intelligence, biohacking, and systems biology intersect to create a smarter approach to health and longevity. You'll also learn how understanding immune balance, metabolism, and mitochondrial function helps build resilience and extend your lifespan. This is essential listening for anyone serious about biohacking, hacking human performance, and extending longevity through personalized medicine, functional biology, and cutting-edge AI innovation. This is essential listening for anyone serious about biohacking, hacking human performance, improving mobility, and extending longevity. You'll also learn how neuroplasticity, metabolism, and brain optimization all connect to the way you move. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: AI medicine, Digital twins, Functional medicine, Biohacking, Longevity, Immune system, Inflammation, Personalized medicine, GLP-1 therapy, Metformin, NAD boosters, Mitochondrial function, Metabolism, AGI, Clinical trials, Human performance, Aging research, Systems biology, Immunology, Smarter Not Harder Thank you to our sponsors! BrainTap | Go to http://braintap.com/dave to get $100 off the BrainTap Power Bundle. MASA Chips | Go to https://www.masachips.com/DAVEASPREY and use code DAVEASPREY for 25% off your first order. Our Place | Head to https://fromourplace.com/ and use the code DAVE for 10% off your order. ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order Resources: • Keep up with Derya's work: https://x.com/derya_?lang=en • Business of Biohacking Summit | Register to attend October 20-23 in Austin, TX https://businessofbiohacking.com/ • Danger Coffee: https://dangercoffee.com/discount/dave15 • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 00:00 — Trailer 01:25 — Intro 02:26 — AI's Role in Extending Lifespan 02:56 — Regulatory Frameworks and Medical Adoption 05:19 — Problems with the Immune System 08:19 — Chronic Fatigue and Long COVID Research 10:32 — Modern Testing and Multi-Omic Analysis 14:07 — Personal Longevity Strategy and Supplements 15:17 — Understanding Exhausted Cells 23:43 — Personalization in Medicine and AI Analysis 31:35 — Longevity Escape Velocity 36:13 — AI Doctors and Prescriptions 39:55 — Data Quality Concerns in AI Training 43:19 — The Future of Wearable Technology 45:50 — Revolutionizing Education with AI 49:04 — The Future of Higher Education 52:03 — Future of Work and AI Agents See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Elizabeth Marnik, also known as Science Whiz Liz, grew up unvaccinated, yet she is now an immunologist, science communicator, and advocate for vaccines–this is her story. Host: Cindy Leifer Guest: Elizabeth Marnick Subscribe (free): Apple Podcasts, RSS, email Become a patron of Immune! Links for this episode MicrobeTV Discord Server More about Liz on her webpage ScienceWhizLiz on Instagram From the Science Classroom with Science Whiz Liz on Substack Time stamps by Jolene Ramsey. Thanks! Music by Tatami. Logo image by Blausen Medical Send your immunology questions and comments to immune@microbe.tv Information on this podcast should not be construed as medical advice.
In this solo episode, I'm sharing five surprising fertility secrets that most people don't know, but should! These insights may completely shift how you view your reproductive health and help you uncover areas that could be holding you back. From the surprising link between gum health and fertility, to the fact that you can bleed monthly without actually ovulating, to how seasons, light exposure, and immune balance all play a powerful role in conception, this episode is packed with practical tools and eye-opening science. Whether you're actively trying to conceive, planning ahead, or simply curious about the deeper connections between your body and fertility, these insights will empower you to take charge of your journey. Key Takeaways: Gum and dental health directly impact sperm quality, egg health, and time to conception. You can have a regular period without actually ovulating, here's how to truly confirm ovulation. Fertility can vary with the seasons, with research showing higher conception rates in autumn and winter. Light exposure and circadian rhythm play a major role in hormone balance and reproductive health. Immune balance is critical for implantation, too much or too little activity can block pregnancy. Disclaimer: The information shared on this podcast is for educational and informational purposes only and is not intended as medical advice. Please consult with your healthcare provider before making any changes to your health or fertility care. Fertilysis Uterine Microbiome Test: https://www.fertilysis.com Use coupon code: WHOLESOMEFERTILITY for a discount. MIRA at home hormone testing: https://mira-fertility.pxf.io/Gm4AXV Use coupon code: WHOLESOMEFERTILITY FOR 15% OFF! Ready to discover what your body needs most on your fertility journey? Take the personalized quiz inside The Wholesome Fertility Journey and get tailored resources to meet you exactly where you are: https://www.michelleoravitz.com/the-wholesome-fertility-journey For more about my work and offerings, visit: www.michelleoravitz.com Curious about ancient wisdom for fertility? Grab my book The Way of Fertility: https://www.michelleoravitz.com/thewayoffertility Join the Wholesome Fertility Facebook Group for free resources & community support: https://www.facebook.com/groups/2149554308396504/ Connect with me on social: Instagram: @thewholesomelotusfertilityFacebook: The Wholesome Lotus Disclaimer: Some of the links shared are affiliates but this is at no cost to you and can even get you discounted prices!
How is the immune system linked to the menopause? Immunologist Dr Jenna Macciochi joins Liz to reveal the crucial role our immune system plays in how we age and how we experience this transition.Jenna explains why we need to broaden our definition of our immune system to improve our health span, and walks Liz through the knock-on impact changing hormones can have on the immune system. They also take a look at the science of inflammaging and senescent cells.Plus, expect practical information on how to best support your immune system as you move through menopause (and beyond).Links mentioned in the episode:Immune to Age: The game-changing science of lifetime health by Dr Jenna Macciochi A Better Second Half by Liz EarleHave a question for Liz? Send a WhatsApp message or voicenote to 07518 471846, or email us at podcast@lizearlewellbeing.com for the chance to be featured on the showPlease note, on some occasions, we earn revenue if you click the links and buy the products, but we never allow this to bias our coverage and always honestly review. For more information please read our Affiliate Policy. Hosted on Acast. See acast.com/privacy for more information.
Beating Cancer Daily with Saranne Rothberg ~ Stage IV Cancer Survivor
On today's episode of Beating Cancer Daily, Saranne welcomes functional medicine expert Jacqui Bryan to discuss powerful yet manageable steps for boosting immune resiliency through nutrition and lifestyle—particularly for those living with or recovering from Stage IV cancer. Together, they explore the latest science-backed approaches to nurturing the immune system year-round, emphasizing the importance of gut health, strategic nutrient choices, and realistic lifestyle changes. Listeners learn how small changes in diet and daily routines can have a measurable, positive impact on both cancer outcomes and overall well-being.Jacqui Bryan is a certified nutritional specialist, whole health educator, certified health coach, and registered nurse specializing in functional and holistic medicine for individuals facing cancer and chronic illnesses. With over two decades of survivorship herself, Jacqui's expertise focuses on empowering people through food-based and lifestyle approaches rooted in the latest research.“Every day our immune system is under attack in some way, shape, or form, whether it's from stress, lack of sleep, chemotherapy, radiation, or chemicals in our environment.” ~Jacqui BryanToday on Beating Cancer Daily:· Building immune resiliency is possible even through small, incremental changes rather than radical overhauls· Seventy to eighty percent of immune cells are housed in the gut, making gut health central to immune function· Prioritizing nutrients such as vitamin C, vitamin D, zinc, probiotics, antioxidants, and omega-3 fatty acids can powerfully support immunity.· Choosing food-first strategies, favoring minimally processed, whole foods, offers a safer and more sustainable approach than supplements during treatment.· Top immune-boosting foods include garlic, ginger, turmeric, green tea, and mushrooms, all of which contain potent protective compounds.· Limiting added sugars is vital, as sugar can suppress immune activity for hours after consumption.· Lifestyle behaviors, regular physical activity, sufficient sleep, and supportive social connections work synergistically with nutrition to strengthen immune defenses.· Always consult with medical providers before introducing new supplements or making significant changes, especially during cancer treatment.Guest Contact Information: Jacqui Bryan 2025 People's Choice Podcast Awards Finalist Ranked the Top 5 Best Cancer Podcasts by CancerCare News in 2024 & 2025, and #1 Rated Cancer Survivor Podcast by FeedSpot in 2024 Beating Cancer Daily is listened to in over 130 countries across 7 continents and features over 390 original daily episodes hosted by Stage IV survivor Saranne Rothberg. To learn more about Host Saranne Rothberg and The ComedyCures Foundation:https://www.comedycures.org/ To write to Saranne or a guest:https://www.comedycures.org/contact-8 To record a message to Saranne or a guest:https://www.speakpipe.com/BCD_Comments_Suggestions To sign up for the free Health Builder Series live on Zoom with Saranne and Jacqui, go to The ComedyCures Foundation's homepage:https://www.comedycures.org/ Please support the creation of more original episodes of Beating Cancer Daily and other free ComedyCures Foundation programs with a tax-deductible contribution:http://bit.ly/ComedyCuresDonate THANK YOU! Please tell a friend whom we may help, and please support us with a beautiful review. Have a blessed day! Saranne
The energy drink industry is rapidly evolving — moving beyond sugary caffeine bombs toward functional wellness beverages that support performance, recovery, and immunity. In a must-hear episode of the Ash Said It Show, Mocean CEO Tony Vieira breaks down how his new brand is redefining what energy means for modern adults. Launching October 2025, Mocean is a low-calorie, low-carb, and taurine-free energy drink designed for fitness-focused, health-conscious consumers. It's packed with a powerful blend of echinacea, elderberry, ginseng, magnesium, and shiso — a rare botanical making its first-ever appearance in U.S. beverages.
A 45-minute hot bath raises your core body temperature by 1.1 degrees C (2 degrees F) and boosts cardiac output as much as a moderate-intensity cardio workout Hot water immersion increases immune activity, helps control inflammation, and supports immune surveillance Compared to traditional and infrared saunas, hot baths triggered the strongest cardiovascular and immune responses due to water's more efficient heat transfer Very hot water dries out your skin, alters its pH, and disrupts your skin microbiome, especially if you have eczema, rosacea, or sensitive skin You can reduce risks by keeping bath sessions under 30 minutes, moisturizing with coconut oil immediately afterward, and rotating with sauna usage if hot baths irritate your skin
Immune discusses the potential future of delivering vaccines by flossing your teeth and how antibodies in human milk shape the normal immune responses in newborns. Hosts: Vincent Racaniello, Cindy Leifer, Steph Langel, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become a patron of Immune! Links for this episode MicrobeTV Discord Server Floss-based vaccination (Nat Biomed Engineering 2025) Press article on Floss-based vaccine paper (Sci News) Human milk IgA promotes immune development (PNAS 2025) Time stamps by Jolene Ramsey. Thanks! Music by Tatami. Immune logo image by Blausen Medical Send your immunology questions and comments to immune@microbe.tv Information on this podcast should not be construed as medical advice.
In this episode of HSS Presents, rheumatologist Dr. Anne Bass is joined by Dr. Deanna Jannat-Khah of HSS and Dr. Michael Postow of Memorial Sloan Kettering to explore immune checkpoint inhibitor–induced arthritis. They discuss how life-saving immunotherapies for cancer can trigger inflammatory joint disease, the challenges of balancing tumor control with autoimmune toxicity, and the latest evidence on safe use of steroids and biologics. The panel also highlights ongoing research into mechanisms, phenotypes, and long-term outcomes, underscoring the importance of multidisciplinary care for cancer patients who develop musculoskeletal complications from immunotherapy.
Welcome to part 2 of the Immune system conversation. If you missed part one, go back one, and tune into that episode. We are here to help shed light on the fact our bodies are always speaking to us. Giving us hints, nudges, and insight on what it's needing. Our emotions play a huge roll in this. We are connected to our emotions more than you might know. So get comfy, tune in and share this episode with your loved ones. You never know the impact it will have. #immunesupport #emotionalsupportwithoils #emotionsstoredinthebody #mindandbody #essentialoils Get this Book! Link for Essential Emotions book https://amzn.to/3Qd1PJv Are you ready to release emotions that have been weighing you down? Book a session today! Book with Vicki: https://vickilebrilla.com/coaching Book with Sarah: https://sarahsepos.com/coaching Vicki's Link- http://referral.doterra.me/1214454 Sarah's Link- https://referral.doterra.me/107766 Get your FREE Sample of VMG (US listeners Only) https://theessentialoilscoop.com/vmgsamples Scoop of the Day Diffuser Blend 3 Petitgrain 3 Bergamot 3 Siberian Fir Welcome into our little essential oil world where we talk about the physical and emotional support of our essential oils. Hi friends, don't forget to leave us a review, your feedback is always welcome, and helps this podcast reach more ears. Join us in our New Facebook Community! Connect on Instagram We upload a brand new episode every Tuesday and Thursday! Want to learn more about us? theessentialoilscoop.com Remember to like, share, and subscribe to our podcast so you will be notified every time we upload a brand new episode. Leave us a review as well, your feedback is always welcome. Also opt-in to our newsletter at https://theessentialoilscoop.com/newsletter If you have any questions or have subject ideas you would like us to cover please email us at theessentialoilscoop@gmail.com Tag us on socials using #theessentialoilscoop #essentialoilpodcast #oilpodcast Disclaimer: Welcome to The Essential Oil Scoop Podcast. We want to remind our listeners that the information provided in this podcast is for educational purposes only and should not be considered as a substitute for professional medical advice, diagnosis, or treatment. The use of essential oils is a personal choice and should be done at your own risk. We are not medical professionals and cannot diagnose, treat, or prescribe any medical condition. Please consult with a qualified healthcare provider before using any essential oils or making changes to your healthcare routine. Any information or opinions expressed in this podcast are those of the hosts and guests and do not necessarily reflect the views of any particular organization. Thank you for listening.
In this episode, we discuss Immune to age, gut health to brain health, inflammation to hormonal shifts and combating autoimmune diseases. Dr Jenna Macciochi is an immunologist specialising in understanding how nutrition, movement, and lifestyle interact with the immune system in health and disease. She holds a PhD from Imperial College London and is a senior lecturer at The University of Sussex, a performance breathwork coach, and Director of Science + Innovation at Ancient+Brave. Known for blending scientific expertise with practical guidance and actionable lifestyle changes inspired by her Scottish farm-to-table roots and Italian Heritage, she can be found on Instagram and Substack. She regularly appears in the press to provide clear, reliable, actionable insight into our body's most misunderstood system.Buy Immune to Age here: https://www.amazon.co.uk/dp/1399822535?linkCode=ogi&th=1&psc=1&tag=superofcom09-21If you want to contact the show to ask a question and get involved in the conversation, then please email us: unquestionablepod@gmail.comFind us here:Twitter: @unquestionpodInstagram: @unquestionablepodTik Tok: @unquestionablepodFacebook: @unquestionablepodcastYoutube: @unquestionablepod Hosted on Acast. See acast.com/privacy for more information.
A UT San Antonio Health Science Center researcher has found that people with resilient immune systems can live 15 years longer than those who don't, but what is immune resilience? How do you know if your immune system is lagging? Can you get some of those years back?
In this special Tick Boot Camp Podcast episode recorded live at Project Lab Coat during New York Fashion Week (NYFW), we sit down with Dr. Michal “Mikki” Caspi Tal, Principal Scientist in the Department of Biological Engineering at MIT and Associate Scientific Director of the MIT Center for Gynepathology Research. Dr. Tal is an immunologist and immunoengineer whose groundbreaking research focuses on the connections between infections and chronic diseases, including Lyme disease and long COVID. At her Tal Research Group lab, she studies why some people recover quickly after infection while others develop chronic illness, with a focus on the immune system's different responses in men and women. What You'll Learn in This Episode How Dr. Tal's lab uses mouse models of chronic Lyme and a large clinical study to take a deeper look at Lyme disease. Why some patients make a protective immune response while others develop catastrophic responses like dysautonomia, MCAS, gynecological issues, or clotting disorders. How her team is moving beyond “yes/no” antibody tests to create new biomarker diagnostics that can guide treatments. Why sex differences matter in chronic illness and why women are more likely to experience long-term symptoms after infection. How her research could lead to more personalized treatment approaches for Lyme disease patients by grouping individuals based on immune response patterns. What samples (blood, saliva, sweat, tissue) her team is collecting at MIT to uncover new insights into chronic Lyme disease. Why this research brings hope to Lyme patients who feel unseen and unheard. About Dr. Michal Caspi Tal Principal Scientist, MIT Department of Biological Engineering Associate Scientific Director, MIT Center for Gynepathology Research Focus areas: Lyme disease, long COVID, chronic inflammatory diseases, sex differences in immune response, predictive diagnostics Background: PhD in Immunobiology from Yale (mentored by Dr. Akiko Iwasaki), postdoctoral training at Stanford (Irving Weissman lab), infectious disease research leader at Stanford's Institute for Stem Cell Biology and Regenerative Medicine. Awards: NIH NIAID F31 and F32 Fellowships, Bay Area Lyme Foundation Emerging Leader Award About Project Lab Coat at New York Fashion Week Project Lab Coat was a groundbreaking event held on September 13, 2025, during New York Fashion Week (NYFW). The show brought together prominent celebrities, researchers, doctors, and advocates who were invited to walk the runway to spotlight Lyme disease and raise funds for Lyme disease research. For the first time, the global visibility of NYFW was used to highlight one of the fastest-growing infectious diseases in the world. Tick Boot Camp co-founders Matt Sabatello and Rich Johannesen, together with Dr. Tal, walked the runway at Project Lab Coat, joining leaders from medicine, science, entertainment, and advocacy. Project Lab Coat demonstrated the power of mainstream platforms to bring awareness, credibility, and resources to the fight against Lyme disease. Why This Episode Matters For too long, chronic Lyme patients have been told their symptoms are “all in their head.” Dr. Tal's work at MIT proves otherwise by measuring the real biological differences in immune system responses. This research not only validates patients' experiences but also charts a course toward better diagnostics, clinical trials, and personalized treatments.
What if everything you thought you knew about childhood health—and the medicine meant to protect it—was wrong? In this high-voltage episode of Rush to Reason, Dr. Kelly Victory joins John Rush for a conversation that starts with a jolt and never lets up. They dissect Robert F. Kennedy Jr.'s much-hyped press conference on autism, where Tylenol took center stage. Is acetaminophen really the culprit, or is it just a convenient decoy hiding something far more alarming? Dr. Kelly questions decades of medical assumptions, tracing the rise in autism rates alongside an explosion in vaccines recommended for pregnant women and young children. She challenges listeners to consider the overlooked connection between pain relievers, vaccination timing, and neurological health. Could the real story be about how often—and how early—we challenge a baby's immune system? The debate deepens as she explains why pain relief during pregnancy has become a medical puzzle. If Tylenol is off the table, what's left—opiates? And why did so many studies ignore a critical factor: vaccination status? Parents' testimonies of children who regressed after routine shots sharpen the stakes. In the 1960s, a child might receive six to eight vaccines; today, that number can reach eighty-four. Are we overwhelming fragile immune systems for the sake of convenience? Could repeated “foreign protein” injections be driving the surge in autoimmune disorders and allergies we never used to see—while countries with fewer vaccines and no mandates report far lower autism rates? If good health can't be injected, how many of these shots are truly necessary? Listen and decide for yourself.
Fentanyl: No One is Immune Guest: Kevin deBruyckere, former head of federal policing in British Columbia By Stuart McNish “In 2013, in my role as Head of Federal Policing in British Columbia, I started to see an increase in drug-related deaths attributed to a powder form of fentanyl being delivered by mail,” says Kevin deBruyckere. “On May 23rd 2014, it hit home for my family – my 22-year-old son lost his life and our family became a victim of the fentanyl epidemic.” Over the next decade, more than 16,000 people have lost their lives due to overdoses in British Columbia. Vancouver is at the epicentre of this epidemic. “Unless there is a significant reframing of response to the drug crisis, we can't beat it. It's not a law enforcement challenge or issue only – it's much larger than that,” says deBruyckere. “This is a public health issue; it's a housing issue; it's an educational issue; it's a prevention issue,” says deBruychkere. The costs to take on the drug epidemic are significant. The costs of not having a coordinated long-term strategy are much larger. “People are dying, families are being destroyed, and all of society is paying a price,” says deBruyckere. We invited Kevin deBruyckere to join us for a Conversation That Matters about fentanyl and the devastating impact it is having. You can see the interview here https://www.conversationsthatmatter.ca/ Learn More about our guests career at careersthatmatter.ca
Make sure to check the rest of the description for all of our social media links, including our Patreon (patreon.com/DoNotRelent)! It's true, Immunization says his goodbyes on this fateful episode (NOT CLICKBAIT! ACTUALLY HAPPENS!) leaving Slidewhistle and Aaron to carry on the show in his memory. And...well let's just say that was a poor decision on his part. Brewfest is celebrated, raid is begrudgingly analyzed, and a surprising amount of Civil War history is touched upon? Join us for Immunization's send-off special and make sure to let him know how great he did over these past 6 years in the comments! Please send all your love mail, hate mail, and well wishes for Immune's next career to @DoNotRelentPod (Twitter) or on gmail at DoNotRelentPod@gmail.com! We will respond to literally anything and read it on the pod. Find us at: Patreon: patreon.com/DoNotRelent Linktree: donotrelent.com (go here for our Discord) YouTube: @donotrelent on YouTube (the link is long and ugly) Instagram: www.instagram.com/donotrelent Twitter: twitter.com/DoNotRelentPod Livejournal: donotrelentpod.livejournal.com E-Mail: DoNotRelentPod@gmail.com Finally, if you feel so inclined, please rate us on iTunes and bonusroll.gg. We will take a shot on air in your honor! Every rating helps! :D
More than 63% of U.S. adults drink at least one sugar-sweetened beverage daily, rapidly disrupting gut bacteria, weakening immune defenses, and damaging the gut barrier at a genetic level Researchers found that the sugar in soda flips bacterial DNA “switches” within days, changing immune signals and gut wall strength, but stopping sugar reverses these effects quickly Artificial sweeteners in diet sodas alter gut microbe balance, lower diversity, and promote inflammatory bacteria, harming immunity and metabolism even without sugar or calories Inorganic phosphate in soda absorbs into the bloodstream nearly 100%, spiking hormones that deplete calcium, suppress vitamin D, stress the kidneys, and harden the arteries Sugar and phosphate together create a rapid, sustained metabolic storm, undermining gut health, hormone balance, and cardiovascular function from multiple angles at once
Hour 2 of John and Lance with John Granato and Lance Zierlein! Luis Garcia's career is most likely done after another season ending surgery for 2026 The Texans are desperate for a win vs the Titans with their brutal upcoming schedule How good do you think the leadership chemistry is between CJ Stroud and DeMeco Ryans? How responsible is Joe Espada for the Astros struggles?
A strong immune system is essential for health at any age, but especially when we're striving for longevity. Everyday factors — including stress, exercise, sleep, nutrition, and more — shape the status of our immune health. In this episode, Jim LaValle, RPh, CCN, speaks to the many influences on our immune system and offers practical strategies for boosting immune function, including metrics for monitoring it and some innovative therapies. This episode of Life Time Talks is part of our series on Performance and Longevity with MIORA. Find the episode highlights, get related resources and view the transcript for this episode at https://experiencelife.lifetime.life/podcast/how-to-build-immune-resilience Have thoughts you'd like to share or topic ideas for future episodes? Email us at lttalks@lt.life — we'd love to hear from you! Follow us on Instagram: @lifetime.life The information in this podcast is intended to provide broad understanding and knowledge of healthcare topics. This information is for educational purposes only and should not be considered complete and should not be used in place of advice from your physician or healthcare provider. We recommend you consult your physician or healthcare professional before beginning or altering your personal exercise, diet or supplementation program.
Immune health is intricately connected to nutrition, genetics, and activity level, with each person requiring a unique approach based on their genetic makeup and lifestyle. Chris ties in how nutrition, genetics, supplements and immunity all relate for active people and athletes. Educational only; not medical advice.You'll hear about:The one plate shift most athletes overlook—and why it changes everythingA simple number that helps you right-size protein for longevity and immunityHow certain genetics can influence your immune health, food choices and supplement strategyA surprising pre-race sip that showed promise in a study
Join Professor Iain McInnes for the latest episode of Discussing RA on The Immune-Mediated Inflammatory Disease Forum. In this episode, he highlights two papers: risk of MACE, VTE, and malignancies in patients with RA or UC treated with filgotinib and frequency of reporting of MACE, MI, and stroke between JAKis and anti-TNFα.
BUFFALO, NY - September 24, 2025 – A new #research paper was #published in Volume 16 of Oncotarget on September 22, 2025, titled “Loss of Trp53 results in a hypoactive T cell phenotype accompanied by reduced pro-inflammatory signaling in a syngeneic orthotopic mouse model of ovarian high-grade serous carcinoma.” In this study, led by first author Jacob Haagsma and corresponding author Trevor G. Shepherd from the Verspeeten Family Cancer Centre and Western University, Canada, researchers investigated how the loss of Trp53 – a critical tumor suppressor gene – affects immune responses in ovarian cancer. The team found that deleting Trp53 led to more aggressive tumor growth and a weaker immune response. These findings help explain why some ovarian tumors may be resistant to immunotherapy and point to new ways to improve treatment. High-grade serous ovarian carcinoma (HGSC) is a deadly cancer that is often diagnosed at a late stage. Immunotherapy, which enhances the body's immune system to fight cancer, has shown limited effectiveness in treating this type of cancer. To better understand why, the researchers developed a mouse model that closely mimics human HGSC. They injected ovarian epithelial cells, with and without Trp53, into the fallopian tubes, the origin site of most ovarian cancers. “In this study, we developed a syngeneic model reflecting both the site of origin and the genotype of early HGSC disease by deleting Trp53 in mouse oviductal epithelial (OVE) cells.” Mice injected with cells lacking Trp53 developed faster-growing and more invasive tumors, reflecting how the disease typically progresses in humans. These tumors also had fewer active T cells, which are immune cells responsible for attacking cancer. Moreover, the T cells that were present appeared less capable of responding to the tumor, creating an immune environment that allowed cancer to grow uncontrolled. Further analysis revealed that tumor cells without Trp53 had reduced activity in genes related to inflammation. These changes were associated with lower levels of key proteins that normally help immune cells detect and attack tumor cells. When the researchers collected tumor cells from the abdominal fluid of the mice—a condition that simulates advanced-stage disease—they observed even lower immune signaling than before. This suggests that as the tumor spreads, it becomes better at evading the immune system. This study highlights how early genetic mutations can shape the interaction between tumors and the immune system. In particular, the loss of Trp53 appears to trigger a chain of events that weakens immune surveillance and accelerates tumor progression. These findings emphasize the need to consider both genetic mutations and the tumor environment when designing immunotherapies for ovarian cancer. Understanding how genes like Trp53 influence immune behavior may lead to more effective treatments and help identify which patients are most likely to benefit from immunotherapy. DOI - https://doi.org/10.18632/oncotarget.28768 Correspondence to - Trevor G. Shepherd - tshephe6@uwo.ca Abstract video - https://www.youtube.com/watch?v=WFQw0psuC3M Sign up for free Altmetric alerts about this article - https://oncotarget.altmetric.com/details/email_updates?id=10.18632%2Foncotarget.28768 Subscribe for free publication alerts from Oncotarget - https://www.oncotarget.com/subscribe/ To learn more about Oncotarget, please visit https://www.oncotarget.com and connect with us: Facebook - https://www.facebook.com/Oncotarget/ X - https://twitter.com/oncotarget Instagram - https://www.instagram.com/oncotargetjrnl/ YouTube - https://www.youtube.com/@OncotargetJournal LinkedIn - https://www.linkedin.com/company/oncotarget Pinterest - https://www.pinterest.com/oncotarget/ Reddit - https://www.reddit.com/user/Oncotarget/ Spotify - https://open.spotify.com/show/0gRwT6BqYWJzxzmjPJwtVh MEDIA@IMPACTJOURNALS.COM
Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Prognostic Value of Biomarkers in Cancer Patients Treated With Immune Checkpoint Inhibitor Therapy.
We're bringing back another great episode for our special Menopause Matters Season – this time with the brilliant Angela Counsel. Angela is a naturopath, kinesiologist, and mindset coach working with women in midlife. Like me, she's on a mission to spread the word that menopause doesn't have to be a struggle. It can be a time of stepping into your wisdom and falling in love with yourself and your life. This conversation was recorded at a time when Covid-19 was very much part of our everyday lives, so we talk a lot about how to support both our hormonal balance and our immune systems in that context. Angela shares deep knowledge and practical tips, all grounded in her belief that midlife is a time of empowerment, not decline. This conversation is very much grounded in Lifestyle Medicine. Here's what we cover: -How our jobs can impact our health -How a miscarriage led Angela to study naturopathy -The impact of stress on women's bodies and how it can cause early menopause -The importance of hormonal balance at all stages of our lives -How it's not normal to experience lots of symptoms around the time of menopause, if we do that means there are issues that need to be dealt with -The many unnatural products in our lives that can impact our health -The impact of stress on our immune systems and immune -related health issues -If you struggle to get over a minor illness such as a cold then your immune system isn't working properly -Never getting sick is not necessarily a good thing either -The body's natural response to viral illness and how we can get in the way of that -Our over reliance on taking a pill to get better -Eating better, cleaner food to avoid pesticides -Vinegar can help to remove waxy coatings on fruit and pesticides -Eating organic if you can, especially if soft like broccoli and berries -Stress, fear and toilet paper -Alcohol, stress and the impact on menopause -The impact of vitamin D levels on people's Covid response -Why Australia has coped comparatively well with the pandemic And lots more! If you enjoyed this episode, please subscribe, share it and leave us a 5* review on Apple Podcasts or wherever you're listening. Order Rachel's book, Magnificent Midlife: Transform Your Middle Years, Menopause And Beyond, recommended in The New York Times as one of seven top books about menopause at magnificentmidlife.com/book The paperback can also be purchased on Amazon or other online retailers: UK: https://www.amazon.co.uk/Magnificent-Midlife-Transform-Middle-Menopause/dp/173981150X/ US & Canada: https://www.amazon.com/Magnificent-Midlife-Transform-Middle-Menopause/dp/173981150X/ Australia: https://www.amazon.com.au/Magnificent-Midlife-Transform-Middle-Menopause/dp/173981150X/ You can listen to all the other episodes and get the show notes at magnificentmidlife.com/podcast. Podcast recommended by the Sunday Times. Feedspot #9 in 40 Best Midlife Podcasts and #7 in 60 Best Women Over 50 Podcasts You'll find lots of strategies, support, and resources to help make your midlife magnificent at magnificentmidlife.com. Check out Rachel's online Revitalize Experience, a 6-week intensive small group mentoring experience or 1-1 Midlife Mentoring.
If you are looking to avoid the fall sickness that usually occurs, this episode is for you. We won't be talking about trendy hacks or some over the counter supplement. We will be looking at the foundations for great immune health including the role our hormones play, minerals and micronutrient considerations, exercise, stress, sleep, and more. Please send this to someone you care about and let's finish 2025 strong! Time Stamps: (0:40) Our Immune System (3:30) Why Everyone Gets Sick This Time of Year (9:30) Hormones and Immunity (13:00) Important Minerals and Micronutrients (15:50) Exercise and Immunity (18:10) Immunity and Stress (20:25) Sleep and Immunity (22:29) Hydration and Immunity ---------- Apply for SF Coaching Method https://sarahfechter.ac-page.com/sfhq-cc Complimentary Health Content https://sarahfechter.ac-page.com/Health_Wellness_Community ---------- Follow Me On Instagram - https://www.instagram.com/sarahfechter.ifbbpro/ Check Out My Website - https://www.sarahfechter.com ---------- This Podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, other professional health care services, or any professional practice of any kind. Any reliance on the information provided in this Podcast is done at your own risk and Sarah Fechter Fitness LLC expressly disclaims any and all liability or responsibility for any direct, indirect, incidental, special, consequential or other damages arising out of any individual use of, reference to, reliance on, or inability to use, this Podcast or the information presented in this Podcast. All contents and design for this Podcast are owned by Sarah Fechter Fitness LLC. Always consult your professional team before beginning any exercise or nutrition program.
Jake Aronoff is a human biologist studying immune function and aging from an evolutionary and ecological perspective. During his PhD, he studied how stress and social inequality impacts inflammation and immunosenescence in the Philippines and US. He is currently a postdoctoral researcher at ASU studying inflammation and aging with Ben Trumble and the Tsimane Health and Life History Project. These studies focus on the development of chronic inflammation in later life (inflammaging), the links between metabolic and immune function (immunometabolism and meta-inflammation), and the relationship between infections, inflammation, and brain aging. His research also utilizes life history theory and energetic trade-offs to understand complex changes in biological functioning in later life, like the simultaneous occurrence of inflammaging and immunosenescence. ------------------------------ Find the paper discussed in this episode: Aronoff, J. E., Trumble, B. C. (2025). An evolutionary medicine and life history perspective on aging and disease: Trade-offs, hyperfunction, and mismatch, Evolution, Medicine, and Public Health, 13(1), 111–124. https://doi.org/10.1093/emph/eoaf010 Aronoff, J. E., Koning, S. M., Adair, L. S., Lee, N. R., Carba, D. B., Kuzawa, C. W., & McDade, T. W. (2024). Intimate partner violence, depression, and chronic low-grade inflammation among middle-aged women in Cebu, Philippines. American journal of human biology : the official journal of the Human Biology Council, 36(6), e24053. https://doi.org/10.1002/ajhb.24053 ------------------------------ Contact the Sausage of Science Podcast and the Human Biology Association: Facebook: facebook.com/groups/humanbiologyassociation/, Website: humbio.org, Twitter: @HumBioAssoc Chris Lynn, Co-Host Website: cdlynn.people.ua.edu/, E-mail: cdlynn@ua.edu, Twitter:@Chris_Ly Anahi Ruderman, SoS Co-Producer, HBA Junior Fellow. E-mail: ruderman@cenpat-conicet.gob.ar.
This week's episode will be focusing on Immune Thrombocytopenia Purpura ( ITP). We will go all the important details on causes, mechanism, diagnosis and treatment. The last time we covered this topic was in Sept 2022, and this comes up ALL the time in heme consults, and there will definitely be board review questions. It may also be tested on IM boards.
Dr. Ari Vojdani, Chief Scientific Officer at Cyrex Labs, describes the two primary components of the immune system--humoral and cell-mediated immunity and how the Cyrex diagnostics are designed to measure both. The Cyrex food immune reactivity testing measures antibodies against raw, cooked, modified, and processed food proteins as the structure of these proteins can change and affect immune responses. Cyrex is also developing tests to measure antibodies against various gut bacteria, fungi, and toxins, and how these relate to autoimmune conditions. Ari explains, "Cyrex performs lots of tests, but we can divide them based on the immune system. As you know, the immune system has two major components, the humoral and cell-mediated immunity. The humoral components of the immune system deal with measurements of antibodies. So when we get exposed to certain antigens, proteins of pathogens, food, or toxic chemicals, when they bind to human tissue, our body reacts to them, and the end result of that is specific antibody production against that specific protein or antigen." "The second component of the immune system is cell-mediated immunity, which looks at different lymphocytes, their markers, such as whether it is a T-cell, B-cell, CD4, CD8, T helper 1, T helper 2, regulatory T cells, or natural killer cells. So that also could be abnormal in certain inflammatory and autoimmune disorders. That's why at Cyrex, the tests that they are performing are classified based on humoral and cell-mediated immunity." "In 1986 and 1987, I developed the ELISA method for measuring antibodies against different food antigens. Then I did not have the knowledge about the importance of raw versus cooked or raw versus modified foods. I established the methodologies, and many others came to visit my laboratories. Years later, they started their own laboratories. So they continue using the same raw food for measuring antibodies in their own laboratories." #CyrexLabs #FunctionalImmunology #FunctionalMedicine #immuneHealth #FoodSensitivity #FoodAllergies cyrexlabs.com Listen to the podcast here
Dr. Ari Vojdani, Chief Scientific Officer at Cyrex Labs, describes the two primary components of the immune system--humoral and cell-mediated immunity and how the Cyrex diagnostics are designed to measure both. The Cyrex food immune reactivity testing measures antibodies against raw, cooked, modified, and processed food proteins as the structure of these proteins can change and affect immune responses. Cyrex is also developing tests to measure antibodies against various gut bacteria, fungi, and toxins, and how these relate to autoimmune conditions. Ari explains, "Cyrex performs lots of tests, but we can divide them based on the immune system. As you know, the immune system has two major components, the humoral and cell-mediated immunity. The humoral components of the immune system deal with measurements of antibodies. So when we get exposed to certain antigens, proteins of pathogens, food, or toxic chemicals, when they bind to human tissue, our body reacts to them, and the end result of that is specific antibody production against that specific protein or antigen." "The second component of the immune system is cell-mediated immunity, which looks at different lymphocytes, their markers, such as whether it is a T-cell, B-cell, CD4, CD8, T helper 1, T helper 2, regulatory T cells, or natural killer cells. So that also could be abnormal in certain inflammatory and autoimmune disorders. That's why at Cyrex, the tests that they are performing are classified based on humoral and cell-mediated immunity." "In 1986 and 1987, I developed the ELISA method for measuring antibodies against different food antigens. Then I did not have the knowledge about the importance of raw versus cooked or raw versus modified foods. I established the methodologies, and many others came to visit my laboratories. Years later, they started their own laboratories. So they continue using the same raw food for measuring antibodies in their own laboratories." #CyrexLabs #FunctionalImmunology #FunctionalMedicine #immuneHealth #FoodSensitivity #FoodAllergies cyrexlabs.com Download the transcript here
When September hits, I always say it's like a second “New Year.” Schedules tighten, routines reset, and — let's be honest — the germs start flying. It is cootie season! packed classrooms, sports getting kids run down while exposure is increased. Between classrooms, sports teams, offices, and the changing seasons, our immune systems can be suddenly challenged. And this year, I want your family armed and ready — not with fear, but with resilience.I am going to talk about the basics, the foundations of immune health: the basics I wrote about in my book, get out of hormone hell. sleep, nutrition, hydration, and those sneaky daily habits that can either help or hurt. Because before you even think about supplements or fancy immune tonics, the truth is, like with any illness or complaint: if the basics aren't in place, your defenses are only half-built.So grab a notebook, maybe even your kids, and let's dive in.
Broadcast from KSQD, Santa Cruz on 9-18-2025: Dr. Dawn opens by establishing her psychobiology background and introducing the neurohormonal axis connecting mind and body. She describes revolutionary research published in Nature Neuroscience showing that simply seeing sick people in virtual reality triggers actual immune responses. The study used VR avatars displaying infection symptoms approaching participants, measuring brain activity with EEG and fMRI while analyzing blood samples for immune cell changes. The research demonstrates that infectious avatars approaching in virtual reality activate the same immune pathways as actual flu vaccination. Brain areas including the salience network and peripersonal space system detect potential threats and communicate with the hypothalamus to trigger white blood cell activation. Proximity matters - threats 20 feet away don't trigger responses, but approaching threats do. Dr. Dawn explains the sophisticated methodology, including 128-channel EEG monitoring and flow cytometry analysis of immune markers. Participants showed faster reaction times when infectious avatars approached compared to neutral ones, demonstrating subconscious threat assessment. The study reveals built-in disgust responses that evolved to protect against pathogens. She comments on how her medical training rewire the protective disgust reaction through repeated exposure.. She transitions to discussing stress effects on gastrointestinal function, explaining how the gut-brain axis operates through the vagus nerve and neurohormonal pathways. The adrenal glands produce both immediate epinephrine responses and longer-term cortisol release, with chronic stress leading to digestive disruption, increased intestinal permeability, and microbiome changes that can trigger food sensitivities and autoimmune conditions. Dr. Dawn details the difference between acute and chronic stress responses in the gut. Acute stress redirects energy from digestion for fight-or-flight responses, while chronic stress causes mast cell activation, histamine release, mucus layer thinning, and bacterial overgrowth. These changes can lead to irritable bowel syndrome, increased food allergies, and even celiac disease in genetically susceptible individuals. The discussion covers various brain networks including the default mode network active during rest, the central executive network for problem-solving, and the salience network that switches between them when detecting important stimuli like threats, food, or reproductive opportunities. Functional MRI studies show these networks' activity patterns and their connections to immune system regulation through the hypothalamus. Dr. Dawn emphasizes practical implications for modern life, warning that constant screen exposure and doom-scrolling activate chronic stress responses unnecessarily. She recommends avoiding phones upon waking, spending time outdoors, wearing amber glasses for evening screen use, and practicing specific breathing techniques - inhaling for 5 counts, holding for 5, exhaling for 5, holding for 5 - to regulate nervous system activation and reduce inflammatory responses.
Host: Peter Buch, MD, FACG, AGAF, FACP Guest: Yinghong Wang, MD, PhD, MS Immune checkpoint inhibitor (ICI) colitis comes with unique diagnostic and treatment challenges, which means that recognizing and managing it effectively is key to the best outcomes. Joining Dr. Peter Buch to share her insights on caring for patients with this complex condition is Dr. Yinghong Wang. Dr. Wang is a Professor in the Department of Gastroenterology, Hepatology, and Nutrition at MD Anderson Cancer Center in Houston, Texas, as well as Director of the Oncology-GI Toxicity Program, Director of Fecal Microbiota Transplantation, Deputy Division Head of Research in the Division of Internal Medicine, and Chair of the MD Anderson Cancer Center Immunotherapy Toxicity Working Group.
EP. 231: On this episode we're digging into one of the most exciting frontiers in cellular medicine: how Urolithin A, a powerful compound, supports mitochondrial health and slows the effects of aging at the cellular level. If you've been feeling low energy, dealing with inflammation, or noticing your strength and resilience aren't what they used to be, this episode is packed with science-backed insights to help recharge your body from the inside out. My guest today is Dr. Brad Currier, PhD, Manager of Clinical Trials at Timeline, who's leading the way in Urolithin A research. We're talking muscle metabolism, brain health, immunity, and how this prebiotic compound could be a total game changer for longevity and overall vitality. → Head to timeline.com/DRTYNA to get started & Use code DRTYNA at checkout to receive 20% off today! Topics Discussed: → What is Urolithin A and how does it help mitochondria? → How does Urolithin A support muscle and metabolism? → How are postbiotics, gut health, and GLP-1s connected? → What does Mitopure research show for immunity and brain health? → How can you use Timeline's Urolithin A daily? Sponsored By: → Head to timeline.com/DRTYNA to get started & Use code DRTYNA at checkout to receive 20% off today! On This Episode We Cover: → 00:00:00 - Introduction → 00:01:19 - Understanding Urolithin A → 00:05:24 - Mitochondrial health → 00:09:08 - Mitochondrial lifecycle → 00:11:08 - Muscular growth & health → 00:14:21 - Mitopure research → 00:17:50 - Postbiotics & the gut microbiome → 00:22:14 - GLP1s & the gut → 00:26:31 - Gut rehabilitation → 00:28:03 - Aging → 00:31:26 - High protein diets & strength training → 00:34:45 - Aging + muscle strength → 00:39:34 - Mitopure, HRT, + stacking → 00:46:21 - Skincare + topicals → 00:49:25 - Immune health + inflammation → 00:52:37 - Summary → 00:56:27 - Trying Timeline! Show Links: → Dr. Tyna's Strength Corner Further Listening: → EP. 196 | The Answer Is The Gym | Quick + Dirty → Strength Training Playlist Check Out Timeline → Head to timeline.com/DRTYNA to get started & Use code DRTYNA at checkout to receive 20% off today! Disclaimer: Information provided in this podcast is for informational purposes only. This information is NOT intended as a substitute for the advice provided by your physician or other healthcare professional, or any information contained on or in any product. Do not use the information provided in this podcast for diagnosing or treating a health problem or disease, or prescribing medication or other treatment. Always speak with your physician or other healthcare professional before taking any medication or nutritional, herbal or other supplement, or using any treatment for a health problem. Information provided in this blog/podcast and the use of any products or services related to this podcast by you does not create a doctor-patient relationship between you and Dr. Tyna Moore. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent ANY disease.
Becoming bed-ridden at 17 years old, Ava wondered what (or if) her love story could ever be. But in the wake of chronic disease, she found hope, healing AND love! In this episode, Ava Pompa, shares her journey full of unexpected surprises and what it has taught her about faith, relationships, and how we live today.Connect with Christian or find her book "Break Up with What Broke You" at ChristianBevere.com
Creatine isn't just for athletes — it fuels brain function, immune response, and recovery from stress and illness by supporting how your cells make and recycle energy Older adults, vegetarians, and those with brain fog or long COVID are especially likely to benefit from creatine, as natural production and intake often fall short Daily creatine supplementation improves memory, learning, and executive function in aging adults, including those with Alzheimer's disease When combined with resistance training, creatine helps build lean muscle, speed recovery, and reduce the risk of frailty-related falls and fractures Grass fed red meat is one of the best food sources, but supplementing 3 to 5 grams of creatine monohydrate daily is a safe and effective way to increase levels
Creatine Without the Bloat: Con-Cret's Founder on HCL vs. MonohydrateClick On My Website Below To Schedule A Free 15 Min Zoom Call:www.Over40FitnessHacks.comOver 40 Fitness Hacks SKOOL Group!Get Your Whoop4.0 Here!Mark Faulkner - Con-Cret SupplementsSocial Media: @concret_creatinewww.Con-Cret.comBrad opened by sharing your personal experience with creatine monohydrate — its benefits for strength and endurance, but also the downside of bloating and water retention that kept you from using it consistently. Mark clarified that “HCL” vs. “hcl” is just a marketing capitalization difference and explained that creatine hydrochloride (HCL) can offer the same benefits with fewer side effects due to its superior bioavailability.Mark shared his science-heavy background (physics, biochemistry, toxicology) and his experience co-founding a forensic toxicology lab. His team built the NFL's steroid testing program, which sparked his interest in safe, legal performance enhancers. After selling the lab, he partnered with sports medicine researchers to find steroid alternatives that could help athletes recover and maintain strength safely. This search led to creatine HCL, which showed strong results for strength, endurance, and recovery without the typical side effects of monohydrate.Bioavailability & Efficiency: Creatine HCL is more easily absorbed due to its chemical structure and compatibility with stomach acid (HCL), allowing smaller doses to deliver more creatine to muscle, brain, and immune cells.Side Effects: Princeton research shows over 50% of men and 75% of women experience bloating and GI distress with monohydrate, which is largely avoided with HCL.Performance Benefits: Faster recovery, increased training capacity, and leaner muscle gains compared to monohydrate.Mark emphasized that creatine supports all cells — not just muscles:Brain health & cognition: Supports energy for thinking and memory.Immune system: T-cells upregulate creatine receptors before attacking pathogens or abnormal cells (e.g., cancer), so adequate creatine helps them “win the fight.”Disease prevention & longevity: The CDC is investigating low creatine levels as a factor in rising chronic disease rates.Mark provided a three-tier approach:Daily Health: 750 mg per day for most people.Exercise / Biohacking: 750 mg per 100 lbs of body weight 30–60 minutes pre-workout (double up on very strenuous days).Medical/Disease States: Higher doses (up to 4–6 g daily) split into multiple servings.He also noted that creatine should be taken daily with no need to cycle off, and extra doses can help with fatigue, poor sleep, or jet lag.Mark stressed that over 90% of creatine is made in China, and quality can vary dramatically. Con-Cret is the only U.S.-made creatine, manufactured in an NSF-certified facility in Nebraska, ensuring purity and safety for athletes who undergo drug testing. Con-Cret holds multiple patents for its creatine HCL technology, further setting it apart.If you're interested in online personal training or being a guest on my podcast, "Over 40 Fitness Hacks," you can reach me at brad@over40fitnesshacks.com or visit my website at:www.Over40FitnessHacks.comAdditionally, check out my Yelp reviews for my local business, Evolve Gym in Huntington Beach, at https://bit.ly/3GCKRzV
Cindy speaks with Aimee Pugh Bernard from University of Colorado about her career and her passion for teaching and communicating immunology to the public. Host: Cindy Leifer Guest: Aimee Pugh Bernard Subscribe (free): Apple Podcasts, RSS, email Become a patron of Immune! Links for this episode MicrobeTV Discord Server More about Aimee on her webpage Funsizeimmuninja on Instagram Fun Size Science video partnership with Unbiased Science Funsizeimmuninja Substack Society for Leukocyte Biology Time stamps by Jolene Ramsey. Thanks! Music by Tatami. Logo image by Blausen Medical Send your immunology questions and comments to immune@microbe.tv Information on this podcast should not be construed as medical advice.
On tonight's show, we recognize National Immune Thrombocytopenia Awareness Month with Dr. Amit Mehta, hematologist and medical oncologist at Premier Hematology & Oncology in Cary, North Carolina. Dr. Mehta will share what immune thrombocytopenia is, how it impacts patients and families, and details about a new FDA approved treatment now available for adults living with this rare blood disorder.
On this Make A Difference Minute, Dr. Amit Mehta, hematologist and medical oncologist at Premier Hematology & Oncology in Cary, North Carolina, shares what to look for when it comes to immune thrombocytopenia (ITP), a rare blood disorder that can cause serious bruising and bleeding. Sponsor: Bankston Motor Homes BankstonMotorHomes.com
Stress, inflammation, gut and nervous system health are all interconnected. The good news is, treating one often helps to improve the others. Specifically, if you're experiencing any type of stressor, it would be beneficial to improve your vagus nerve and gut health. In this episode, I'll walk through the top treatments that work for stopping high stress and creating long term balanced mental health. ✅Start healing with us! Learn more about our virtual clinic: https://drruscio.com/virtual-clinic/
Can a witch really curse a Christian? Or are believers in Jesus completely protected from witchcraft and curses?We're diving into this controversial debate on witchcraft, curses, and spiritual warfare. Can Christians be cursed by witches? Some say yes, others say no. We'll look at arguments presented by Chris Rosebrough, Fighting for the Faith, who argues against the power of curses, and Jennifer LeClaire, who claims Christians can be affected. Most importantly, we'll dig into what the Bible actually says about witches, curses, and the spiritual authority of believers in Christ.ORIGINAL VIDEOS:https://www.youtube.com/watch?v=SAmPJm-spHw&t=4shttps://www.youtube.com/watch?v=-SKkdsr46Q0 Subscribe to The Remnant Radio newsletter and receive our FREE introduction to spiritual gifts eBook. Plus, get access to: discounts, news about upcoming shows, courses and conferences - and more. Subscribe now at TheRemnantRadio.com.Support the showABOUT THE REMNANT RADIO:
Today, I'm sitting down with the brilliant Dr. Joy Kong, a trailblazing clinician and scientist at the forefront of regenerative medicine and stem cell therapy. In this episode, Dr. Kong shares how she blends rigorous science with hands-on clinical practice to help people tackle everything from brain injuries and autoimmune conditions to skin aging and joint pain—often with transformative results. Products she mentions: CharaOmni facial cream Episode Timestamps: How stem cells address chronic illness ... 00:07:12 When to use IV vs. local stem cells ... 00:10:06 Types and sources: autologous, umbilical, MSCs ... 00:11:40 Why younger stem cells are superior ... 00:17:38 Emerging cell therapies: V-cells, Muse cells ... 00:20:25 Decline of stem cells with age ... 00:24:19 Stem cell therapy for neurological, organ, and autoimmune conditions ... 00:27:14 Techniques to target brain and optimize therapy ... 00:29:46 Donor screening and safety ... 00:34:41 Stem cells in healing injuries and recovery ... 00:42:28 Immune modulation and overall rejuvenation ... 00:44:56 Anti-aging protocols: frequency of IV therapy ... 00:48:36 Aesthetic uses: skin, microneedling, hair ... 00:50:08 Handling and potency of exosomes ... 00:55:01 Future of anti-aging and stem cell therapy ... 00:59:02 Legality and access in the US ... 01:03:13 Our Amazing Sponsors: Wizard Sciences - NMN+G Rx: A scientifically formulated blend of NMN, ginsenosides from Panax ginseng, and apigenin. Together, they enhance mitochondrial function, boost NAD+ levels, and support cellular repair. Go to wizardsciences.com and look for NMN+G. Use code NAT15 at checkout to get 15% off your purchase. Ultimate GI Repair by LVLUP Health - Whether you're struggling with digestive discomfort or want to strengthen your gut health, Ultimate GI Repair provides the comprehensive support your body needs to restore balance. The ingredients are unmatched! Visit https://lvluphealth.com/ and use code NAT at checkout for 20 % off. Body Cream by Young Goose - Powered by NAD+ APEX, CelVio Spermidine, and targeted peptides, this advanced formula restores cellular energy, supports collagen production, and enhances skin resilience. It clears cellular waste, improves skin texture, and deeply hydrates areas where aging shows most—like arms, legs, neck, and décolleté. Visit YoungGoose.com—use code NAT10 to get started, or 5NAT if you're an existing customer. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Group
Very easy one to enter, follow both pages and comment how YOU look after your gut health on the reel. Thats it. Winners announced on Thursday. Best of luck. https://www.instagram.com/brian_keane_fitness/?hl=en
Contributor: Travis Barlock MD Educational Pearls: Meningitis retention syndrome is a relatively novel and rare clinical condition Aseptic meningitis + acute urinary retention One study reports an incidence of about 8% in patients with acute aseptic meningitis Clinical presentation Typical meningeal symptoms including fever, stiff neck, and headache Urinary retention occurs about one week after initial symptoms Potential pathophysiology Immune-mediated dysfunction of the central nervous system Detrusor muscle underactivity from inflammation of the spinal cord Management Supportive care Bladder decompression References Hiraga A, Kuwabara S. Meningitis-retention syndrome: Clinical features, frequency and prognosis. J Neurol Sci. 2018;390:261-264. doi:10.1016/j.jns.2018.05.008 Pellegrino F, Funiciello E, Pruccoli G, et al. Meningitis-retention syndrome: a review and update of an unrecognized clinical condition. Neurol Sci. 2023;44(6):1949-1957. doi:10.1007/s10072-023-06704-0 Summarized & Edited by Jorge Chalit, OMS4 Get your tickets to Tox Talks Event, Sept 11, 2025: https://emergencymedicalminute.org/events-2/ Donate: https://emergencymedicalminute.org/donate/
Emotions were high on Capitol Hill this week as a bipartisan group of lawmakers stood beside survivors of Jeffrey Epstein, demanding the release of all files related to the case. Meanwhile, HHS Secretary Robert F. Kennedy Jr. sparred with senators from both sides of the aisle during a hearing focused on the recent shakeup at the CDC and his vaccine stances. FOX News Senior Congressional Correspondent Chad Pergram breaks down the latest developments from Capitol Hill. Later, Senator Roger Marshall (R-KS) explains why he believes an overhaul is needed at the Bureau of Labor Statistics, and how lawmakers can find middle ground on vaccines. Learn more about your ad choices. Visit podcastchoices.com/adchoices
Anurag Singh is currently Chief Medical Officer at Timeline that develops next generation advanced nutritional and skincare products targeting improvements in mitochondrial and cellular health. With a M.D. in internal medicine and a Ph.D. in immunology, his experience includes work for top consumer health (Nestlé, Nestlé Health Science) and startups companies (Amazentis/Timeline). He’s authored > 50 articles for top science journals, been awarded >20 patents and has designed and led > 50 randomized clinical trials. His research over the past decade across multiple clinical trials on the postbiotic Urolithin A (Mitopure) and its health benefits has led to the launch of multiple consumer products. Full show notes: bengreenfieldlife.com/timelineimmunity Episode Sponsors: Jaspr: Breathe air so clean you can smell the difference with the Jaspr commercial-grade air purifier. Visit Jaspr.co/ben and use code BEN for 10% off. Troscriptions: Explore Troscriptions' revolutionary buccal troche delivery system that bypasses digestion to deliver pharmaceutical-grade, physician-formulated health optimization compounds directly through your cheek mucosa for faster onset and higher bioavailability than traditional supplements. Discover a completely new way to optimize your health at troscriptions.com/BEN or enter BEN at checkout for 10% off your first order. Timeline Nutrition: Give your cells new life with high-performance products powered by Mitopure, Timeline's powerful ingredient that unlocks a precise dose of the rare Urolithin A molecule and promotes healthy aging. Go to shop.timeline.com/BEN and use code BEN to get 20% off your order. Organifi: Get the restful sleep you need with the most soothing ingredients! Organifi is a delicious superfood tea with powerful superfoods and mushrooms to help you sleep and recover so you can wake up refreshed and energized. Go to Organifi.com/Ben for 20% off your order. Truvaga: Balance your nervous system naturally with Truvaga's vagus nerve stimulator. Visit Truvaga.com/Greenfield and use code GREENFIELD30 to save $30 off any Truvaga device. Calm your mind, focus better, and recover faster in just two minutes. Quantum Upgrade: Recent research has revealed that the Quantum Upgrade was able to increase ATP production by a jaw-dropping 20–25% in human cells. Unlock a 15-day free trial with the code BEN15 at quantumupgrade.io.See omnystudio.com/listener for privacy information.
Neurons. Immune systems. MRIs. Weed gummies? One of the greats in neurology, Dr. Aaron Boster, takes time to chat all about Multiple Sclerosis, a neurological autoimmune disease close to our hearts. Alie's mom, your grammapod a.k.a. Fancy Nancy, was diagnosed with MS over two decades ago, and this episode explores in depth the factors that can cause MS, therapies that do – and don't – show promise, how diet, exercise and mindfulness actually can help folks who have MS, the oftentimes agonizing journey to a diagnosis, and advice for those who've MS for a while – or are newly in the community. Also: yeah, weed. Visit the Boster Center for Multiple Sclerosis and follow Dr. Boster on YouTubeA donation went to MS Views and NewsMore episode sources and linksOther episodes you may enjoy: Disability Sociology (DISABILITY PRIDE), Diabetology (BLOOD SUGAR), Post-Viral Epidemiology (LONG COVID), Dolorology (PAIN), Salugenology (WHY HUMANS REQUIRE HOBBIES), Psychedeliology (HALLUCINOGENS), Cardiology (THE HEART), Somnology (SLEEP)400+ Ologies episodes sorted by topicSmologies (short, classroom-safe) episodesSponsors of OlogiesTranscripts and bleeped episodesBecome a patron of Ologies for as little as a buck a monthOlogiesMerch.com has hats, shirts, hoodies, totes!Follow Ologies on Instagram and BlueskyFollow Alie Ward on Instagram and TikTokEditing by Mercedes Maitland of Maitland Audio Productions and Jake ChaffeeManaging Director: Susan HaleScheduling Producer: Noel DilworthTranscripts by Aveline Malek Website by Kelly R. DwyerTheme song by Nick Thorburn
Dr. Dominic D'Agostino (@DominicDAgosti2) is a tenured associate professor in the Department of Molecular Pharmacology and Physiology at the University of South Florida Morsani College of Medicine and a Visiting Senior Research Scientist at the Institute for Human and Machine Cognition.This episode is brought to you by: Helix Sleep premium mattresses: https://HelixSleep.com/Tim (27% off all mattress orders)Momentous high-quality creatine: https://livemomentous.com/tim (code TIM for up to 35% off)AG1 all-in-one nutritional supplement: https://DrinkAG1.com/Tim (1-year supply of Vitamin D plus 5 free AG1 travel packs)Timestamps:[00:00:00] Start.[00:14:43] Why I'm interested in ketogenic strategies for neurodegenerative prevention.[00:16:18] Mary and Steve Newport's ketone-linked temporary cognitive improvements.[00:18:18] A mechanisms overview for Alzheimer's/dementia.[00:21:25] The immune system as longevity's "fifth horseman" — and why metabolic control is key.[00:22:04] How to measure ketones and GKI.[00:23:00] Fasting vs. ketogenic diet.[00:24:18] There's nothing fishy about sardine fasting.[00:28:32] My hiatal hernia discovery and increased cancer risk concerns.[00:30:04] HSCRP as a superior biomarker to LDL for cardiovascular risk.[00:31:57] Glucose tolerance testing revelations and CGM importance.[00:31:57] Upgrading the metabolic machinery through keto without getting bored.[00:42:07] What do do if you, like Dom and me, are among the 30% who suffer from cholesterol hyperabsorption.[00:43:42] Dom's day-to-day diet regimen.[00:45:56] How Dom optimizes his aging dogs with ketones, SARMs, and supplements.[00:51:30] Supplementing for sleep disruption while fasting.[00:55:41] Why Dom doesn't have misgivings about melatonin.[00:59:15] Shingles prevention through fasting protocols.[01:00:15] Immune system modulation: Innate vs. adaptive, vegan vs. ketogenic.[01:03:54] Dom at 50-something: Current meal timing and composition.[01:05:57] Blue zone observations: Greek and Sardinian longevity habits.[01:08:16] Ketogenic diet initiation tips: MCT, electrolytes, and fasted cardio.[01:15:18] Ketone metabolic therapy for cancer.[01:18:15] The metabolic psychiatry revolution.[01:22:10] The soothing effects of hyperbaric oxygen and ketosis on seizure sufferers.[01:28:27] Metformin vs. berberine.[01:31:43] The low-dose neuroprotective potential of GLP-1 drugs.[01:34:58] NAD research: MIB-626 and stabilized forms for mitochondrial health.[01:39:48] Idebenone, CoQ10, and the Deanna protocol for ALS.[01:42:05] Dom's supplement short list: CoQ10, creatine, ketones, vitamin D, melatonin.[01:44:43] KetoNutrition.org, Metabolic Health Summit, Audacious Nutrition, veteran-focused research protocols, and other parting thoughts.*Show notes for this episode: https://tim.blog/2025/09/03/dr-dominic-dagostino-all-things-ketones/For show notes and past guests on The Tim Ferriss Show, please visit tim.blog/podcast.For deals from sponsors of The Tim Ferriss Show, please visit tim.blog/podcast-sponsorsSign up for Tim's email newsletter (5-Bullet Friday) at tim.blog/friday.For transcripts of episodes, go to tim.blog/transcripts.Discover Tim's books: tim.blog/books.Follow Tim:Twitter: twitter.com/tferriss Instagram: instagram.com/timferrissYouTube: youtube.com/timferrissFacebook: facebook.com/timferriss LinkedIn: linkedin.com/in/timferrissSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Get my FREE weightloss videos (The Secrets to How I Lost 100lbs): www.nobsfreecourse.com For years, I thought women who didn't struggle with food were some kind of unicorns. Born with magic metabolisms. Craving celery instead of chips. Immune to late-night binge urges. But after coaching thousands of women—and losing 100lbs myself—I finally figured it out: They're not magical. They're just doing a few key things differently. And here's the wild part: None of it requires willpower. Or motivation. Or some perfect diet plan. In this episode, I'm breaking down the five things women who don't struggle with food actually do—and how you can start doing them too. You'll learn: The daily mindset shifts that help them eat like a “normal person” What they don't do when the scale goes up or a day goes off-plan How they stay consistent without obsessing over every bite If you've ever wondered, “Why is this so easy for some people?”—this is your episode. Listen now and start seeing what's actually possible… not just for “them,” but for you.