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L-Glutamine stands as one of the most powerful amino acids for optimizing gut health, muscle function, immune and brain health. It's a common solution for leaky gut, but overall can enhance the improvement of other therapies. In this episode, I'll dive into the benefits of l-glutamine, the best food sources, and effective protocols for different conditions. ✅ Start healing with us! Learn more about our virtual clinic:https://drruscio.com/virtual-clinic/
Every Wednesday afternoon, we'll be talking Making Babies.Andrea will be joined by Professor Shane Higgins, Master of the National Maternity Hospital to cover every area of trying to have a baby. From the very start of knowing how to prepare, right up to pregnancy – and all the bumps in the road in between.This week, Shane joins Andrea to discuss endometriosis, as well as immune testing after two listeners got in touch with their questions…
The Immune team goes up the nose to discuss cytotoxic T cells activating complement through secretion of granzyme K to drive inflammatory nasal polyps and how IgA-producing B cells are made in the nose. Hosts: Vincent Racaniello, Cindy Leifer, Steph Langel, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become a patron of Immune! Links for this episode MicrobeTV Discord Server CD8 T cells in recurrent airway inflammation (Nature 2025) Where IgA producing B cells arise that protect the nose (Nature 2024) Time stamps by Jolene Ramsey. Thanks! Music by Tatami. Immune logo image by Blausen Medical Send your immunology questions and comments to immune@microbe.tv Information on this podcast should not be construed as medical advice.
Overcoming Unexplained Infertility Gut, Immune & Mindset Shifts with Monica Cox Finding Fertility Naturally| Podcast #459 Reach out to Monica FDN: https://www.findingfertility.co/
In this groundbreaking episode of Research Renaissance, host Deborah Westphal reconnects with Dr. Adithya Gopinath, University of Florida, to explore a game-changing discovery in Parkinson's research: a direct connection between dopamine neurons in the brain and the peripheral immune system, specifically the spleen.Dr. Gopinath shares how his lab's findings could reshape the future of Parkinson's diagnosis and treatment—potentially identifying the disease earlier and opening new therapeutic avenues using existing immune-modulating drugs. The episode also touches on surprising implications for conditions like addiction, ADHD, and even cancer.Key Topics Covered:The role of dopamine transporters in both the brain and peripheral immune cellsA newly mapped brain-to-spleen pathway and its implications for Parkinson'sWhy gastric bypass surgery offers unexpected clues about neuroimmune functionHow Parkinson's might eventually be detected through blood biomarkersThe challenge of longitudinal studies and the need for philanthropic supportCrossovers with autoimmune disease, glioblastoma, and methamphetamine useThe future vision for translational research at Dr. Gopinath's labStandout Quote: "If we're able to identify Parkinson's early, we may have the opportunity to either slow or stop its progression. And we might already have the tools—we just need to apply them in the right way." – Dr. Adithya GopinathConnect with Us:
In this episode our listener question is all about how to get your husband to notice dust when he seems immune to dust. In other words... how to get him to get involved in the unpaid labour at home. We talk bout how we tackle the invisible labour and ingrained gender roles in our household, as well as sharing practical steps for dividing tasks, overcoming traditional expectations, and breaking down the mental load. This episode covers writing down tasks, having open conversations, and the importance of mutual respect. We also reflect on personal experiences, the impact of modeling behavior for our kids, and the role that positive feedback plays in making lasting changes. Whether you're managing household chores or parenting duties, this episode offers helpful insights for creating a more balanced and collaborative home life.
What if YOU’RE the problem? Dun dun dun!
In this episode of the SMFM Podcast, Dr. Amy Valent welcomes Dr. Teresa Sparks and Dr. Mary Norton, authors of the upcoming SMFM Consult on the evaluation and management of non-Immune Hydrops Fetalis. Together, they explore updated recommendations on nonimmune hydrops (primarily in singleton gestation) and discuss how MFMs can navigate these challenging cases, support maternal health, and help guide families through difficult decisions. Click here for the full episode transcript. For more educational resources, visit education.smfm.org.
If you've struggled with gut imbalances, recurrent or chronic infections, or you're just curious about upgrading your oral or gut microbiome, this episode of Vitality Radio is a must-listen. Jared welcomes Dr. Shawn Manske, ND, from the Biocidin Clinical Education team to dive deep into one of the most respected formulas in the natural health world—Biocidin. With over 35 years of clinical use and growing popularity, Biocidin is finally available to the public, and it's making a big impact. Dr. Manske breaks down how this unique botanical blend supports microbial balance in the gut, helps maintain oral health, and addresses issues like SIBO, candida, and biofilms. You'll hear why Biocidin stands apart from other antimicrobials—supporting the good guys while targeting the bad. Jared and Dr. Manske also discuss the importance of pairing Biocidin with binders and spore-based probiotics, how to introduce it safely (especially for sensitive individuals), and why it may be a game-changer for immune health, brain fog, and long-standing digestive complaints. They also explore the powerful benefits of Biocidin's oral care products and how the oral microbiome may play a more crucial role in systemic health than most people realize. Products:CellCore Biocidin ProductsCellCore BioToxin BinderVital 5 Precision Probiotic Vital SporesAdditional Information:#543: How to Choose the Right Binder for Detox, Parasites, Mold, and MetalsVisit the podcast website here: VitalityRadio.comYou can follow @vitalitynutritionbountiful and @vitalityradio on Instagram, or Vitality Radio and Vitality Nutrition on Facebook. Join us also in the Vitality Radio Podcast Listener Community on Facebook. Shop the products that Jared mentions at vitalitynutrition.com. Let us know your thoughts about this episode using the hashtag #vitalityradio and please rate and review us on Apple Podcasts. Thank you!Just a reminder that this podcast is for educational purposes only. The FDA has not evaluated the podcast. The information is not intended to diagnose, treat, cure, or prevent any disease. The advice given is not intended to replace the advice of your medical professional.
In this powerful episode of the Tick Boot Camp Podcast, we are joined by Dr. Daniel Warren of Envita Medical Center, a leading voice in the field of regenerative and integrative medicine, to break down the multi-layered complexity of chronic Lyme disease and its treatment. Dr. Warren takes us deep into the root causes of persistent symptoms, highlighting how chronic Lyme often results in immune dysregulation, biofilm-protected pathogens, co-infections, and central nervous system inflammation that go untreated by conventional protocols. The conversation explores the use of VSELS (Very Small Embryonic Like Stem Cells) to regenerate damaged tissue and rebalance immune function, as well as IRAD (Insulin Receptor Antibiotic Delivery)—Envita's proprietary method of delivering antibiotics past the blood-brain barrier to treat neurological Lyme disease. This episode is a must-listen for anyone seeking a deeper understanding of how precision diagnostics, immune modulation, and regenerative medicine can be integrated to support lasting recovery from chronic Lyme and tick-borne disease.
Join us for a powerful conversation with the scientific minds behind Rejuvenate Pro, Aevum Labs' flagship longevity, immune, and gut health formulation. In this expert panel discussion, we explore the clinical research, biochemical pathways, and traditional herbal wisdom that make Rejuvenate Pro a cutting-edge solution for targeting immunosenescence and the hallmarks of aging. Rejuvenate Pro was developed to modulate chronic inflammation, restore immune resilience, support gut barrier integrity, and extend healthspan — using a blend of scientifically validated and synergistic ingredients. What You'll Learn in This Episode: Why immunosenescence drives nearly every age-related disease How Rejuvenate Pro targets key cytokines (↓ IL-6, TNF-α; ↑ IL-10) and chemokines (↓ CXCL9) The roles of IDP®, Immunel®, 20% Carnosic Acid, and Kawakawa in immune modulation How traditional Māori medicine aligns with modern immunology How gut health and immune function are intimately connected The research and development process behind this formulation Meet the Panel: Lisa Tamati - Host & Chief Scientific Officer, Aevum Labs Peter Lehrke - Biochemist & Lead Formulator Mike Eyres - Herbal Medicine Expert Dr. Rod Claycomb - Scientist & Innovation Researcher Whether you're a clinician, health coach, longevity enthusiast, or someone looking to optimise your healthspan, this in-depth panel will give you rare insights into the formulation process and the systems biology approach behind Rejuvenate Pro.
In this episode of Ageless Future Podcast (Health Accelerator Challenge), Regan Archibald explores the underlying causes of chronic inflammation—coined "inflammaging"—and its profound impact on immune health, aging, and disease. He dives deep into the biological mechanisms of cellular senescence, immunosenescence, and how persistent inflammation accelerates aging and impairs immunity. Regan presents cutting-edge solutions such as peptides (e.g., FOXO4, Thymosin Alpha 1, BPC-157), stem cell therapies, umbilical cord plasma, and exosomes that can recalibrate immune function, reduce inflammatory biomarkers, and enhance tissue regeneration. Practical tips include optimizing VO2 max, sleep tracking, and gut health maintenance. Real-life patient outcomes and data-supported strategies highlight how combining movement, nutrition, and regenerative therapies can help prevent chronic illness and extend healthspan. The episode concludes with a challenge: monitor your sleep to gain insights into your immune resilience. www.agelessfuture.com
ReferencesAnal Cell Pathol (Amst).2018; 2018: 787.1814J. Biol. Chem. 2018;293:2422-2437Current Opinion in Structural BiologyVolume 83, December 2023, 102707The Journal of Biological Chemistry 2016.291, 23756-23768Mann, Martinez, O'Neill. 1979 "Angels at My Gate" Manfred Mann EB.https://open.spotify.com/track/2A9wPXzu7uijsOhIpbAH6e?si=2226c50bc7ab4a45Tchaikovsky, PI . 1880. Capricio Italiane" Romeo and Juliet; Nutcracker. https://open.spotify.com/album/0t5AVxOQO5GqqlZW0AeL0c?si=Fwd2uqTtQpqlzhILsRWXQA
Send us a textIn this episode, David McCulley and Betsy Crouch interview Dr. Benjamin Fensterheim, a neonatology physician scientist, who shares his journey through medical training, the inspiration behind his immunology research, and the importance of bridging the gap between basic science and clinical neonatology. The conversation delves into the challenges faced by physician scientists, the evolving landscape of neonatal care, and the need for innovative therapies in the NICU. Dr. Fensterheim emphasizes the significance of community and mentorship in supporting early-career researchers and advocates for the value of science in improving healthcare outcomes for infants.Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!
It's officially barefoot season—and your feet (and body) are ready for it! In this eye-opening episode of the Prime Podcast, Dr. Skip Wyss and Dr. Julie Wyss reveal how going barefoot can strengthen your arches, improve posture, and support your overall health. Learn why flip-flops and unsupportive sandals may be doing more harm than good, and discover the science behind grounding (earthing)—a powerful way to reconnect your body with the earth for reduced stress and better sleep.
Let's get real for a moment. Not “do you feel overwhelmed?” but how overwhelmed are you… right now? If your answer is “way more than I used to be,” you're not alone. In fact, that's the norm for so many women I speak to—feeling maxed out, overstimulated, and constantly on edge. And here's the wild thing: most of us don't even realize how deep into burnout we've gotten until our bodies shut down. Think about it: every day you juggle thousands of decisions, from “What's for dinner?” to managing family schedules, careers, social commitments, and digital overload. Our brains weren't designed for this 24/7 flood of input. Yet, here we are—expected to handle it all with a smile. Compare that to 60 years ago: a black-and-white TV, a single daily paper, and meal plans based on “meat of the day.” Simpler? Yes. Less overwhelming? Definitely. Fast forward to today: social media, constant notifications, and a culture of doing more with less time have pushed us past our biological limits. And the effects are showing up in our nervous systems, hormones, and health. What Overwhelm Actually Does to Your Body That lingering fog, the irritability, the weight that won't budge? It's not in your head. It's in your hormones. Chronic stress triggers a cortisol rollercoaster that can derail your entire endocrine system. Over time, this shows up as: Fatigue and brain fog Irregular cycles and hormonal imbalances Poor sleep Skin and gut issues Immune dysfunction Weight gain and insulin resistance Mood swings or anxiety Here's the truth: you can't fix chronic overwhelm by pushing harder, working out more, or “trying to be positive.” You need the right tools for the job—and that starts with data. That's why I love the DUTCH Hormone Test. It gives a detailed view of what's actually happening in your system, so we can target your healing accurately. No more guessing. No more trying every supplement under the sun. In the Female Hormone Solution Program, we walk you step-by-step through this process: Test your hormones (Dutch Test) Interpret your body's stress and hormone story Build a personalized, science-backed plan to heal with meal guides and coaching Get ongoing support from me and my expert team Most women wait until they're absolutely fried before they reach out. I get it. We're taught to just keep swimming. But if you haven't had six months of calm, uneventful life in the last few years? It's no wonder you feel stuck. Your body is not broken. It just needs time, support, and the right conditions to heal. That's what we do. We match the right tools to your situation. Get on the waitlist now for the next round of the Female Hormone Solution Program. We only work with a limited number of women so we can give you the hands-on attention and results you deserve. Click here to join the waitlist: https://drbethwestie.com/waitlist/
On this episode of Vitality Radio, Jared welcomes back naturopathic physician Dr. Lexi Loch from Terry Naturally to uncover two of the most powerful herbs in natural medicine: Boswellia and Curcumin (from Turmeric). While many are familiar with turmeric for inflammation, few realize that Boswellia (also known as frankincense) targets a completely different inflammatory pathway—one that traditional NSAIDs and pain relievers don't touch. Together, these herbs form a potent, well-researched duo for addressing pain and inflammation in the gut, joints, lungs, and beyond. You'll learn about the unique pathway that Boswellia modulates, the advantages of this unique curcumin extract over conventional turmeric extracts, and how combining the two offers faster and longer-lasting support. Whether you're struggling with IBS, asthma, joint pain, or simply want to manage everyday inflammation more naturally, this episode provides evidence-based insight and practical guidance you can trust.Products:Terry Naturally Boswellia & Curcumin ProductsAdditional Information:#524: Maximum Absorption of Nutrients for Energy, Pain, Immune, and Respiratory Challenges with Dr. Lexi LochVisit the podcast website here: VitalityRadio.comYou can follow @vitalitynutritionbountiful and @vitalityradio on Instagram, or Vitality Radio and Vitality Nutrition on Facebook. Join us also in the Vitality Radio Podcast Listener Community on Facebook. Shop the products that Jared mentions at vitalitynutrition.com. Let us know your thoughts about this episode using the hashtag #vitalityradio and please rate and review us on Apple Podcasts. Thank you!Just a reminder that this podcast is for educational purposes only. The FDA has not evaluated the podcast. The information is not intended to diagnose, treat, cure, or prevent any disease. The advice given is not intended to replace the advice of your medical professional.
ReferencesActa Pharm Sin B. 2019 Sep 3;10(3):414–433Mechanisms of Ageing and Development2016. Volume 156, Pages 25-33The Journal of Biological Chemistry 2018.293: 2422-2437.Anal Cell Pathol (Amst).2018; 2018: 787.1814.Mozart, WA. 1788. Divertimento 563 in E flat majorhttps://music.youtube.com/playlist?list=OLAK5uy_lDd2hLSAScEFRzcwXGJxrKjTTrPB9uDu0&si=xoAXTM_V9fYzT_cOTaylor and Baker 1968. "Passing the Time. Cream Wheels of Fire lphttps://music.youtube.com/playlist?list=OLAK5uy_lDd2hLSAScEFRzcwXGJxrKjTTrPB9uDu0&si=xoAXTM_V9fYzT_cOMeade, N. . 1964. "Time is On My Side." Rolling Stoneshttps://music.youtube.com/watch?v=7jStGLgQkSw&si=ufgxy8kPLG6djqWNCroce, J. 1974. "Time in a Bottle"https://music.youtube.com/watch?v=9h1davKgBYM&si=LEy6JDkroVjcT-lU
ReferencesCellular Signaling 2018 .Volume 46, June :129-134Free Radic Biol Med. 2021 Jul; 170: 59–69. J Vis Exp. 2020 Oct 27:(164)Acta Pharmaceutica Sinica B 2023. Volume 13, Issue 10, October :4089-4104Bruford/Squire/Anderson. 1972. "Heart of the Sunrise" Live Yessongs.https://music.youtube.com/watch?v=Ar_ObQIssRM&si=fE6vosqHz-DA9O17Lennon/McCartney. 1968. "Hello Goodbye" Magical Mystery Tour. Beatleshttps://music.youtube.com/watch?v=ywZqBGHDTlA&si=bBc_qmYfM_VFaVFn
Food doesn't cause IBS. But the fear around food? That's real. In this episode of The Gut Show, I'm talking about when restrictions help, when they don't, and what else could be driving your symptoms. Thank you to our partners: @GemelliBiotech offers trusted, science-backed at-home tests for conditions like SIBO, IMO, ISO, and post-infectious IBS. Their Trio-Smart breath test measures all three key gases: hydrogen, methane, and hydrogen sulfide to detect different forms of microbial overgrowth. And for those with IBS symptoms, IBS-Smart is a simple blood test that can confirm post-infectious IBS with clinical accuracy. You simply order the test, complete it at home, send it back, and get clinically backed results in about a week that you can take to your provider! Find out which tests are right for you at getgutanswers.com and use code ERINJUDGE25 to save $25 on your order! @FODZYME is the world's first enzyme supplement specialized to target FODMAPs. When sprinkled on or mixed with high-FODMAP meals, FODZYME's novel patent-pending enzyme blend breaks down fructan, GOS and lactose before they can trigger bloating, gas and other digestive issues. With FODZYME, enjoy garlic, onion, wheat, Brussels sprouts, beans, dairy and more — worry free! Discover the power of FODZYME's digestive enzyme blend and eat the foods you love and miss. Visit fodzyme.com and save 20% off your first order with code THEGUTSHOW. One use per customer. This episode is made possible with support from Ardelyx. Covered in this episode: Why I work with IBS [3:10] The most common reason for dietary restriction in IBS [4:09] Food intolerance in IBS [6:10] Visceral hypersensitivity [7:45] Immune activation [9:05] Dysbiosis [9:54] Intestinal permeability [10:51] Food does not cause IBS [12:42] (social?) When do restrictions work? [14:01] When restrictions work against you [16:47] Pitfalls to be aware of [23:06] Support for food fear [36:59] How to approach dietary restrictions [45:59] Sustainable ways to approach restrictions [47:27] Non food restriction strategies [51:23] What does managing IBS look like? [52:15] How do you get there? [56:20] Mentioned in this episode: MASTER Method Membership Take the quiz: What's your poop personality? Malabsorption Overlapping With or Masking as IBS Connect with Gutivate: IG: https://www.instagram.com/erinjudge.rd TikTok: https://www.tiktok.com/@erinjudge.rd Work with Gutivate: https://gutivate.com/services
ReferencesFront Immunol. 2017 Jun 9;8:643Acta Pharm Sin B. 2019 Sep 3;10(3):414–433Zappa, F. 1968 "Flower Punk" Mother's of Invention .We are only in it for the Money lp https://music.youtube.com/watch?v=HQfZmMI87P4&si=UyDyEQtzmAivWcMeZappa, F. 1976. "Black Napkins" on Zoot allures lp.https://music.youtube.com/watch?v=RfHT-T6R6WY&si=79BxfAu-YWlrg9wcCouperin, F. 1716. Pieces d' Clavecin. Livre 2. Order 6. les Bergerieshttps://music.youtube.com/watch?v=wOQRIoXptPo&si=D9SawR9a-cMB2qYt
Kevin Caldwell, CEO, President, and Co-Founder of Ossium Health, discusses the opportunities for regenerative stem-cell therapies and the challenges of obtaining bone marrow from donors for bone marrow transplants. Ossium Health is collecting bone marrow from healthy, young donors and utilizing a cryopreservation process that enables long-term storage and on-demand availability of these cells. Ongoing clinical trials using allogeneic bone-marrow-derived cells to treat patients with acute leukemia and myelodysplastic syndrome are showing promising results. Kevin explains, "Our mission is to improve the health, longevity, and vitality of human beings through bioengineering. We believe that regenerative therapeutics, which involve cell and gene therapies that can permanently and positively improve human biology, will be fundamental to the prevention of disease and the preservation of health as we age. One of the most powerful tools we have in achieving this goal is engineering the immune system. And in particular at Ossium, we develop therapeutics that enable us today in the clinic to treat life-threatening malignancies of the immune system, like leukemia, in patients with dire need. Into the future, the goal is to make it possible to reconstitute, reprogram, and replace a blood and immune system in a manner that can treat patients with chronic diseases and ultimately do so in a preventive manner." "Traditionally, the major application of bone marrow in the clinic is bone marrow transplants for patients with blood cancers like leukemia. And so the patient's native immune system is ablated or annihilated and replaced with a bone marrow infusion from a healthy donor, related or unrelated. And if that bone, new bone marrow from the donor in grafts in the patient, then it replaces or it constitutes their blood and immune system." "And so one of the things that we're working on at Ossium is, okay, how do we address these problems? How do we make bone marrow more available to deliver and deploy on demand and easily, without needing to track down a volunteer donor? What can we do to reduce the risk of rejection so that the transplant is safer? What can we do to improve the likelihood of engraftment the first time and the speed of engraftment so the patients aren't immunocompromised for as long? All of these are things that we're working on to really make it possible to bring this lifesaving procedure to more patients." #OssiumHealth #StemCellTherapy #RegenerativeMedicine #BoneMarrowTransplants ossiumhealth.com Download the transcript here
Kevin Caldwell, CEO, President, and Co-Founder of Ossium Health, discusses the opportunities for regenerative stem-cell therapies and the challenges of obtaining bone marrow from donors for bone marrow transplants. Ossium Health is collecting bone marrow from healthy, young donors and utilizing a cryopreservation process that enables long-term storage and on-demand availability of these cells. Ongoing clinical trials using allogeneic bone-marrow-derived cells to treat patients with acute leukemia and myelodysplastic syndrome are showing promising results. Kevin explains, "Our mission is to improve the health, longevity, and vitality of human beings through bioengineering. We believe that regenerative therapeutics, which involve cell and gene therapies that can permanently and positively improve human biology, will be fundamental to the prevention of disease and the preservation of health as we age. One of the most powerful tools we have in achieving this goal is engineering the immune system. And in particular at Ossium, we develop therapeutics that enable us today in the clinic to treat life-threatening malignancies of the immune system, like leukemia, in patients with dire need. Into the future, the goal is to make it possible to reconstitute, reprogram, and replace a blood and immune system in a manner that can treat patients with chronic diseases and ultimately do so in a preventive manner." "Traditionally, the major application of bone marrow in the clinic is bone marrow transplants for patients with blood cancers like leukemia. And so the patient's native immune system is ablated or annihilated and replaced with a bone marrow infusion from a healthy donor, related or unrelated. And if that bone, new bone marrow from the donor in grafts in the patient, then it replaces or it constitutes their blood and immune system." "And so one of the things that we're working on at Ossium is, okay, how do we address these problems? How do we make bone marrow more available to deliver and deploy on demand and easily, without needing to track down a volunteer donor? What can we do to reduce the risk of rejection so that the transplant is safer? What can we do to improve the likelihood of engraftment the first time and the speed of engraftment so the patients aren't immunocompromised for as long? All of these are things that we're working on to really make it possible to bring this lifesaving procedure to more patients." #OssiumHealth #StemCellTherapy #RegenerativeMedicine #BoneMarrowTransplants ossiumhealth.com Listen to the podcast here
In a new pharmaphorum podcast, Aoife Brennan, CEO of Climb Bio, discusses the treatment of immune-mediated diseases. Climb Bio is a clinical-stage biotechnology company developing therapeutics for immune-mediated diseases, and Brennan talks about the potential of B-cell depletion therapies, as well as the challenges and opportunities in developing novel biotechnology. Brennan also speaks to being a female leader in this field. You can also listen to episode 191a of the pharmaphorum podcast in the player below, download the episode to your computer, or find it - and subscribe to the rest of the series – on Apple Podcasts, Spotify, Overcast, Pocket Casts, Podbean, and pretty much wherever else you download your other podcasts from.
I am delighted to have Dr. Aaron Hartman, the founder of Richmond Integrative and Functional Medicine, joining me today as my very first guest in my podcast studio! In our conversation, we dive into the common mood issues women experience during perimenopause and menopause. We explore the immune and inflammatory impact of hormonal changes, the role of protein and key supplements, and the importance of comprehensive nutritional support in preventing chronic disease. Dr. Hartman also highlights the effects of hormone fluctuations, stress, and nutrient deficiencies, as well as the importance of gut health, hormone optimization, and personalized treatment plans in addressing chronic inflammation, trauma, and environmental factors such as mold. This conversation with Dr. Aaron Hartman is full of insight, wisdom, and practical guidance that every middle-aged woman deserves to hear. IN THIS EPISODE, YOU WILL LEARN: How societal expectations exacerbate women's stress and mood issues Dr. Hartman shares his foundational approach to hormone optimization. The value of breath work for managing dysautonomia and trauma Environmental mold and mycotoxins, and their impact on our health The link between Lyme disease and autoimmune disorders Immune system changes menopausal women experience and the protective benefits of estrogen How protein is essential for proper immune functioning, and the benefits of supplementing with whey protein and collagen Addressing inflammation to help women avoid heart disease and cancer Trace minerals in bone broth and benefits to menopausal women maintaining optimal health Potential impact of long-term fasting and low-calorie diets on appetite and overall health Bio: Dr. Hartman's journey with functional medicine started when he & his wife adopted their first daughter from foster care. She has cerebral palsy & countless dietary issues. They went from specialist to specialist and, even as a physician, he felt let down & confused. His daughter's health struggles forced him to confront an uncomfortable realization: Our current healthcare system doesn't have all the answers. His wife, however, refused to give up hope. She ultimately pointed him to functional medicine. His daughter & other two kids began to thrive. After years in family practice, he felt called to make a dramatic shift. He now helps patients identify leverage points in key areas of their lifestyle & health that harness their body's remarkable power to heal and begin living the vibrant life they deserve. He has become the go-to doctor for difficult and complex cases in central Virginia. As a clinical researcher, Dr. Hartman has been involved with over 70 clinical studies. He is the founder of the Virginia Research Center and currently serves as an Assistant Clinical Professor of Family Medicine at the VCU School of Medicine. In 2016, he founded Richmond Integrative and Functional Medicine. Connect with Cynthia Thurlow Follow on X, Instagram & LinkedIn Check out Cynthia's website Submit your questions to support@cynthiathurlow.com Connect with Dr. Aaron Hartman Richmond Integrative and Functional Medicine Made for Health Podcast YouTube Channel
BUFFALO, NY - July 16, 2025 – A new #research paper was #published in Volume 16 of Oncotarget on July 9, 2025, titled “A novel anti-human CD25 mAb with preferential reactivity to activated T regulatory cells depletes them from the tumor microenvironment.” In this study, researchers from the National Institute of Allergy and Infectious Diseases, led by first author Maja Buszko and corresponding author Ethan M. Shevach, discovered a new monoclonal antibody that selectively targets a subset of immune cells called regulatory T cells (Tregs). These cells, while normally important for preventing autoimmunity, also can block the body's ability to fight cancer by suppressing anti-tumor immune responses. This discovery could lead to novel cancer therapies that strengthen the immune system's capacity to attack tumors. The researchers identified an anti-CD25 monoclonal antibody with several atypical properties and named it 2B010. To evaluate its effects, they used humanized mice, laboratory mice that are engineered to carry human immune cells, to closely mimic how human immune systems respond to cancer. The treatment of these mouse models with 2B010 significantly decreased the number of Tregs in tumors and boosted the activity of CD8+ T cells, which are essential for killing cancer cells. Importantly, 2B010 worked without disrupting other key immune functions. Unlike traditional Anti-CD25 antibodies, it did not interfere with interleukin-2 (IL-2) signaling, which is essential for the growth and activity of effector T cells that fight cancer. “2B010 also had no effect on IL-2 induced STAT5 phosphorylation or CD4+ T cell proliferation in vitro while both were blocked by Clone D1 further supporting the view that 2B010 does not recognize the IL-2 binding site.” This finding is especially significant because high levels of Tregs in tumors are associated with poor outcomes in many cancers. By specifically removing these cells, 2B010 may help overcome one of the main barriers to current immunotherapy approaches. Its ability to preserve IL-2 signaling could also make it safer and more effective when used alone or in combination with existing therapies such as immune checkpoint inhibitors. While the 2B010 antibody showed strong effects in reducing Tregs and boosting immune cell activity, the study did not observe changes in tumor size in these models. Researchers suggest this may be due to limitations in the preclinical systems used, such as the lack of tumor-specific T cells in humanized mice. Nevertheless, these findings demonstrate that 2B010 has a unique mechanism of action that could complement other cancer immunotherapies in future clinical trials. In conclusion, the development of 2B010 is a promising step toward selectively disrupting the immune suppressive environment in tumors. As researchers continue to refine and test this antibody, it could become a powerful tool for enhancing the effectiveness of cancer treatments and improving outcomes for patients. DOI - https://doi.org/10.18632/oncotarget.28752 Correspondence to - Ethan M. Shevach - eshevach@Niaid.NIH.gov Video short - https://www.youtube.com/watch?v=2NJcGsI7WXA Sign up for free Altmetric alerts about this article - https://oncotarget.altmetric.com/details/email_updates?id=10.18632%2Foncotarget.28752 Subscribe for free publication alerts from Oncotarget - https://www.oncotarget.com/subscribe/ Keywords - cancer, Treg, CD25, TME, mAb, GVHD To learn more about Oncotarget, please visit https://www.oncotarget.com and connect with us: Facebook - https://www.facebook.com/Oncotarget/ X - https://twitter.com/oncotarget Instagram - https://www.instagram.com/oncotargetjrnl/ YouTube - https://www.youtube.com/@OncotargetJournal LinkedIn - https://www.linkedin.com/company/oncotarget Pinterest - https://www.pinterest.com/oncotarget/ Reddit - https://www.reddit.com/user/Oncotarget/ Spotify - https://open.spotify.com/show/0gRwT6BqYWJzxzmjPJwtVh MEDIA@IMPACTJOURNALS.COM
Coffee is most likely one of your IBS triggers but you just might not know it! I dive into the science of how coffee interacts with our body and gut in this episode.Join the 60 Day gut reset and transform your health! $200OFF with code 'SECRETOFFER! https://checkout.teachable.com/secure/1716725/checkout/order_q9s5bzn3?coupon_code=SECRETOFFERINSTA: @wholistichomeopath
ReferencesFront Immunol. 2017 Jun 9;8:643JAMA. 2021;325(16):1640-1649Journal of Hepatology 2012 56, 704-713DOI:(10.1016/j.Annual Review of Food Science and Technology.2022. Volume 13:263-286Annual Review of Pathological Mechanisms of Disease 2010. 5:99-118.Nature.2013 Jul 4;499(7456):97-101 Nature Reviews Gastroenterology and Hepatology 26 April 2019Cell Metabolism 2019. [29] 4:886-900Lamm, R. 1972. "While the City Sleeps" Chicago Vhttps://music.youtube.com/watch?v=qCrgrGsBlr0&si=oGMvJDfCrd2BU7_ICetera and Seraphine . "Lowdown" Chicago IIIhttps://music.youtube.com/watch?v=6LlZCBbeZTk&si=DrSyAp9lCzhZyqfWLamm, R. 1969. "Questions 67 and 68" CTAhttps://music.youtube.com/watch?v=0TKaFqhmmg4&si=_W-MMatKBBQ0cBF9
Probiotics have a surprising amount of benefits that aren't just for digestion. From cognition and brain fog to depression and autoimmune disease, probiotics have powerful benefits that can improve many conditions. Learn 6 different probiotic benefits and the right protocols to follow to help you heal. Listen now! ✅Start healing with us! Learn more about our virtual clinic: https://drruscio.com/virtual-clinic/
ReferencesThe Journal of Nutritional Biochemistry 2016.Volume 34, pages 1-7Immunologic Research,2020. 1559-0755,Feb, Vol. 68, Issue 1Cell Metabolism 2019. [29] 4:886-900Guerra, DJ.2025. Unpublished LecturesAnderson and Howe. 1971. "Roundabout" Yes.https://music.youtube.com/watch?v=pk3HBb0mh5Q&si=dO7xDgnAVqNl8Yv6Davis, T. 1971 "Your Saving Grace" Steve Miller Bandhttps://music.youtube.com/watch?v=RBJ6teB2IXw&si=etBGUDK87GprtnlrLennon/McCartney 1967. "She's Leaving Home" Beatles SPLHCB.https://music.youtube.com/watch?v=VaBPY78D88g&si=9upPJq5KC_jBDQI0Lennon/McCartney. 1966. "She Said" Revolver, lp Beatleshttps://music.youtube.com/watch?v=rLzfo59AdEc&si=r-AiTLLNsphoME0y
REFERENCESFront Immunol.2019; 10: 1064.ASN Neuro. 2024 Nov 5;16(1):2404367.Int J Mol Sci. 2024 Apr 10;25(8):4199Page/Jones/Plant 1969. "Since I've Been Loving You" LZ III lp.https://open.spotify.com/track/1SDiiE3v2z89VxC3aVRKHQ?si=530d2dcc304f4199Lennon/McCartney, 1964. "I Don't Want to Spoil the Party"https://open.spotify.com/track/3kQDIa85ZK8cKVn72NfBnl?si=be68c3abca6341d8Lennon/McCartney 1967. "A Day in the Life" Sgt Pepper's LHCB. lp.https://open.spotify.com/track/0hKRSZhUGEhKU6aNSPBACZ?si=8589b727398f4fbbBiber, H.I.F. 1676. "Passacaglia in G Minor. Violin sonatahttps://open.spotify.com/track/2PvqhaYNHP4zHQynKeook4?si=479490bfb34c4c2d
ReferencesMol Cancer Ther. 2018 Jan; 17(1): 50–59 J Neuroinflammation. 2019; 16: 236. Cell Host Microbe. 2016 Feb 10; 19(2): 181–193Nat Rev Microbiol. 2009 Feb; 7(2): 99–109.Cells.2020 Feb 5;9(2).Biochimica et Biophysica Acta (BBA) - Biomembranes. 2016.Volume 1858, Issue 11, November Pages 2681-2688Nat Immunol. 2024 Apr 8;25(5):778–789. Dylan, B. 1975. "Tangled up in Blue"https://music.youtube.com/playlist?list=OLAK5uy_nHWCTvQI-G4uNRNvC0AjQr9hVXG54TeSU&si=xOVhlpdBm_ygXirlMcQuinn 1971. "Pale Blue" Byrdmaniax l phttps://youtu.be/Mh3J7GqrdzY?si=UtahiK75LoZhQLe7Baker, G. 1967. "Blue Condition" Cream Disraeli Gears lp.https://youtu.be/bOAkjNX1FDI?si=3q_FcsfvWTH95RyK
Lyme Disease is becoming more common and many people don't even know they have it, which means it often goes untreated. And while you're waiting for your doctor to diagnose you, they'll often shrug off your other symptoms and say thing like "it's all in your head".... TOPICS DISCUSSED IN THIS EPISODE: Why mental illness is more biological than psychological The brain scan that shows inflammation MRIs, your doctor and blood work miss Why some people get infected and never recover - and why some people do Childhood infections like Strep can cause full blown psychiatric changes that are often called ADHD or anxiety PANS, PANDAS, Lyme, Mold and more Autoimmunity and Lyme Disease How these disease can hijack your DNA More from Dr. Eboni Cornish + the Amen Clinics: Clinic Website: www.amenclinics.com Instagram: @dr.ebonicornish Email (Assistant): drcornishassist@amenclinics.com Phone (Virginia Clinic): 703-880-4000 Leave us a Review: https://www.reversablepod.com/review Need help with your gut? Visit my website gutsolution.ca to join a program: Get help now Contact us: reversablepod.com/tips FIND ME ON SOCIAL MEDIA: Instagram Facebook YouTube
Welcome to this revitalizing meditation centered on fostering enhanced immunity and overall wellness as you delve into the twilight stage, those precious moments before drifting into sleep. In this serene interval, you'll effortlessly align your energies, formulate and embody a deep-seated sense of resilience and wellbeing. Unwind now with our positive sleep affirmations podcast. Our soothing affirmations relax the mind and prepare the body for rest. Hit play, and drift into Good Sleep... Listen to more positive sleep affirmations by subscribing to the audio podcast in your favorite podcast app: Apple Podcasts: https://podcasts.apple.com/us/podcast/good-sleep-positive-affirmations/id1704608129 Spotify: https://open.spotify.com/show/3OuJvYoprqh7nPK44ZsdKE And start your morning with Optimal Living Daily! Apple Podcasts: https://podcasts.apple.com/us/podcast/optimal-living-daily-mental-health-motivation/id1067688314 Spotify: https://open.spotify.com/show/1hygb4nGhNhlLn4pBnN00j?si=ca60dcfd758b44b4 Learn more about your ad choices. Visit megaphone.fm/adchoices
Welcome to this revitalizing meditation centered on fostering enhanced immunity and overall wellness as you delve into the twilight stage, those precious moments before drifting into sleep. In this serene interval, you'll effortlessly align your energies, formulate and embody a deep-seated sense of resilience and wellbeing. Unwind now with our positive sleep affirmations podcast. Our soothing affirmations relax the mind and prepare the body for rest. Hit play, and drift into Good Sleep... Listen to more positive sleep affirmations by subscribing to the audio podcast in your favorite podcast app: Apple Podcasts: https://podcasts.apple.com/us/podcast/good-sleep-positive-affirmations/id1704608129 Spotify: https://open.spotify.com/show/3OuJvYoprqh7nPK44ZsdKE And start your morning with Optimal Living Daily! Apple Podcasts: https://podcasts.apple.com/us/podcast/optimal-living-daily-mental-health-motivation/id1067688314 Spotify: https://open.spotify.com/show/1hygb4nGhNhlLn4pBnN00j?si=ca60dcfd758b44b4 Learn more about your ad choices. Visit megaphone.fm/adchoices
ReferencesCell Metabolism 2024. volume 36, Issue 4, 2 April : 839-856.e8Winwood/Davis. 1966 "Giimme Some Lovin" Spencer Davis Group.https://music.youtube.com/watch?v=BuQ3PaFyb9A&si=yAERzThIMPra_Ct1Cochran and Capehart. 1958. "Summertime Blues" The Who Live at Leeds lp.https://music.youtube.com/watch?v=ovHs-psC9F4&si=zLwITLtjW0aCwKPAVivaldi, A 1717-1718. "Summer" Violin Concerto. Marie Samuelson. No. 2 in G minor, Op. 8, RV 315,https://music.youtube.com/watch?v=g65oWFMSoK0&si=jw6PDRYCagn-B4fC
On this episode of Vitality Radio, Jared shares three powerhouse supplements that may not be “new,” but are being used in some of the most impactful ways yet. First up is a clinically studied lutein and zeaxanthin complex that supports eye health, blue light protection, and even cognitive performance—delivered in a delicious gummy called Screen Eyes. Next, Jared breaks down monolaurin, a coconut-derived compound that supports immune resilience by targeting lipid-coated viruses like herpes, Epstein-Barr, and influenza—especially when paired with L-lysine and vitamin C. And finally, he explores two innovative magnesium-based powders from Kal - Clean Out Magnesium and Gut Magnesium, each designed to promote healthy regularity and support cleansing protocols. If you've struggled with constipation or want to fine-tune your immune and visual wellness, this is an episode you don't want to miss.Products:Zhou Screen Eyes Blue Light FormulaMonolaurin & LysineVital-C ImmunityNano-SilverKAL Clean Out Magnesium PowderKAL Gut Magnesium PowderVital 5 Magnesium BisglycinateAdditional Information:#209 VR Short: Centrum SucksVisit the podcast website here: VitalityRadio.comYou can follow @vitalitynutritionbountiful and @vitalityradio on Instagram, or Vitality Radio and Vitality Nutrition on Facebook. Join us also in the Vitality Radio Podcast Listener Community on Facebook. Shop the products that Jared mentions at vitalitynutrition.com. Let us know your thoughts about this episode using the hashtag #vitalityradio and please rate and review us on Apple Podcasts. Thank you!Just a reminder that this podcast is for educational purposes only. The FDA has not evaluated the podcast. The information is not intended to diagnose, treat, cure, or prevent any disease. The advice given is not intended to replace the advice of your medical professional.
YouTube link: https://youtube.com/live/N4rkX1nsfpcSupport the show
ReferencesFront. Immunol., 22 February 2024Sec.Multiple Sclerosis and Neuroimmunology Volume 15 Arthritis Care Res (Hoboken). 2024 Aug 7;76(11):1451–1460Nat Immunol. 2024 Apr 8;25(5):778–789Lake, G 1972 "From the Beginning" ELP Trilogy lp.https://music.youtube.com/watch?v=hsJ9YXHqnr8&si=NoG1BHKOtrFNYItmJoel, B. 1972. "Scenes from An Italian Restaurant. Yhe Stranger lphttps://music.youtube.com/watch?v=rdAvFvDVXSk&si=_BhtdE6WKN2J80FV
From the 2024 Society for Leukocyte Biology meeting, Cindy and Brianne talk with Darren Lee to discuss his career, how he got interested in immunology of the eye, and how his team visualizes immune responses of the eye in real time with the hope of better understanding autoimmune uveitis. Hosts: Cindy Leifer and Brianne Barker Guest: Darren Lee Subscribe (free): Apple Podcasts, RSS, email Become a patron of Immune! Links for this episode MicrobeTV Discord Server The eye is an immunosuppressive environment (Adv Drug Delivery Rev 2023) Tregs control autoimmune uveitis (Sci Rep 2025) TIGIT, Tregs, and autoimmune uveitis (J Leuk Biol 2024) Society for Leukocyte Biology Time stamps by Jolene Ramsey. Thanks! Music by Tatami. Logo image by Blausen Medical Send your immunology questions and comments to immune@microbe.tv Information on this podcast should not be construed as medical advice.
This episode was recorded at the 2025 Florida Ruminant Nutrition Symposium. Dr. Baumgard begins with an overview of his presentation, “Importance of gut health to drive animal performance and health.” He notes the metabolic and inflammatory fingerprint of all stressors is essentially the same, indicating they likely all emanate from the gut. Overall, we're gaining a better understanding of how typical on-farm stressors negatively influence gut barrier function. He thinks the most likely mechanism of leaky gut is the immune cell known as a mast cell. When an animal or human is stressed, the enteric nervous system releases corticotropin-releasing factor, which binds to the mast cell, the mast cell degranulates, and the former contents of the mast cell (TNF-alpha, proteases, histamine, etc.) causes the gut to become leaky. (4:20)Once the GI tract barrier becomes compromised, antigens like lipopolysaccharide (LPS) can infiltrate, stimulating the immune system. Immune activation causes loss of appetite much like any other infection. The gut heals fairly quickly upon removal of the stressor(s), and the gut can also acclimate to stress such that the early stages of a stress event are more severe than later stages. Strategies to combat leaky gut remain scarce, and there is no silver bullet. There are a variety of dietary strategies to target the gut permeability issue itself. Another approach would be to bind pathogens or curb their proliferation at the membrane of the small intestine. (7:06)Dr. Neiehues asks if an antihistamine would work on gut mast cells the way it does in other body systems. Dr. Baumgard isn't sure that's ever been looked at, although there have been some studies in pigs using a product targeted to prevent mast cell degranulation. Dr. Nelson wonders if we should interfere in some of these processes because they're obviously there for a reason. Panelists discuss stress events related to parturition and transition, particularly for first-calf heifers. Dr. Baumgard notes that stacking stressors on top of one another compromises an animal's ability to tolerate stress. (9:28)We know stress can cause ulcers in humans and horses - what about ruminants? Dr. Baumgard thinks it is likely that it's happening, but we aren't looking for it. Few animals who die on-farm do receive a thorough postmortem exam. It could also be that these types of insults to the gut are not visible to the naked eye. (19:11)Dr. Nelson asks what makes some cows, despite all the challenges, able to be up and milking 150 pounds a day in no time after calving. What makes them unique? Dr. Baumgard lists some possibilities, including lower pathogenic inflammation than other cows, less tissue trauma damage to the uterus during calving, and lower sensitivity to immune activation. The panel disagrees with the notion that high-producing cows are stressed. (23:16)Dr. Niehues and Dr. Baumgard trade stories of experiments where cows maintained production even with high stress and inflammatory markers. The panel goes on to discuss subclinical infections and their impact on transition cows. Dr. Nelson notes there are retrospective datasets where cows who had metritis showed decreased feed intake even before calving. Dr. Baumgard feels that the decrease in intake has been incorrectly assumed to be the cause of the metritis. He says the decrease in intake is often around two weeks before calving and he doesn't think it's a coincidence that at the same time, the mammary gland is initiating lactogenesis. He hypothesizes the mammary gland is causing an immune response, resulting in a decrease in intake. Dr. Nelson wonders if measuring somatic cell counts of colostrum would show any differences in mammary gland inflammation during this prepartum period. (29:18)Panelists share their take-home thoughts. (42:02)Please subscribe and share with your industry friends to invite more people to join us at the Real Science Exchange virtual pub table. If you want one of our Real Science Exchange t-shirts, screenshot your rating, review, or subscription, and email a picture to anh.marketing@balchem.com. Include your size and mailing address, and we'll mail you a shirt.
ReferencesFront. Immunol., 22 February 2024. Sec. Multiple Sclerosis and Neuroimmunology Volume 15 Nat Cell Biol. 2019 Mar; 21(3): 397–407.CELL 2006. Volume 126, Issue 3, 11 August Pages 503-514Valenti, D. 1971. "Dont Cry My Lady Love"https://music.youtube.com/watch?v=Aqt0yhGfC1s&si=fXpd1HifSgtEHtpbLennon/McCartney. 1966. "For No One"Revolver. lp.https://music.youtube.com/watch?v=ELlLIwhvknk&si=ZgDZXKn_UPC3RHBmMozart, WA. 1773. Symphony 25 in G Minorhttps://music.youtube.com/watch?v=707oHEGF6l8&si=rwJRSJ2CeYfYVIas
In this episode, host Alyssa Watson, DVM, is joined by John M. Thomason, DVM, MS, DACVIM (SAIM), to talk about his recent Clinician's Brief article, “Top 4 Primary Immune-Mediated Disorders in Dogs.” In part 1 of this 2-part conversation, Dr. Thomason focuses on the diagnosis and management of IMHA and IMTP. You'll hear vital details for both conditions including the right way to handle blood smears and slide agglutination, which IMHA cases are hypercoagulable (spoiler: all of them), and if vincristine actually helps in IMTP (spoiler again: it does).Resources:https://www.cliniciansbrief.com/article/anemia-thrombocytopenia-immune-disorder-dogshttps://www.zoetisus.com/products/dogs/librelaContact:podcast@instinct.vetWhere To Find Us:Website: CliniciansBrief.com/PodcastsYouTube: Youtube.com/@clinicians_briefFacebook: Facebook.com/CliniciansBriefLinkedIn: LinkedIn.com/showcase/CliniciansBrief/Instagram: @Clinicians.BriefX: @CliniciansBriefThe Team:Alyssa Watson, DVM - HostAlexis Ussery - Producer & Multimedia Specialist
ReferencesGuerra. DJ. 2025. Unpublished LecturesFront. Immunol.,2024. 22 February Sec. Multiple Sclerosis and Neuroimmunology Volume 15 .Annals of Clinical & Laboratory Science.2022.vol. 52, no. 5 pp763-771.Mol Biosyst. 2014 Oct;10(10):2505-8. Frey/Henley. 1973. "Desperado" The Eagleshttps://music.youtube.com/playlist?list=OLAK5uy_k3UBMdBe0k-PWX6y1VCLJZVJogoUaKEco&si=9kkmSQG5xcdpbINRWelch, B 1973. "Emerald Eyes" Fleetwood Mac.Mystery to Me lp.https://music.youtube.com/watch?v=DnQM535xV-U&si=sRsNuXaEJ1A4VWPJ
Hormonal shifts in perimenopause and menopause can do more than throw off your cycle—they can actually stir up inflammation, spark strange symptoms, and even trigger immune responses that leave you wondering, what is going on with my body? If you've ever felt like your symptoms don't quite “fit in a box,” this conversation is for you. I sit down with Dr. Tania Dempsey—a brilliant MD and expert in complex, multi-system diseases—to talk about Mast Cell Activation Syndrome (MCAS), why it's often missed in women, and how hormones can play a huge role in triggering it. This episode connects the dots between your immune system, your hormones, and all those mystery symptoms no one's been able to explain. Dr. Tania breaks it down—how mast cells work, what happens when they go rogue, and why midlife women are seeing a rise in things like histamine intolerance, inflammation, and post-viral flare-ups (yes, COVID included). She shares what to look out for, what testing often misses, and how therapies like low-dose naltrexone and even ozone can make a difference. You'll also love hearing Dr. Tania's heart for educating both patients and physicians so women can finally get the answers they deserve. And speaking of support, I've been sipping on my new Mighty Maca Mango lately, and it's a summer fave. Light, zesty, and still packed with all the hormone-balancing goodness of the original, it's perfect over ice or made into popsicles. Check it out at dranna.com—you'll be hooked. Key Timestamps: [00:00:00] Introduction. [00:01:28] Mast cell activation syndrome. [00:06:51] Mast cell activation syndrome prevalence. [00:08:12] Immune system and estrogen dominance. [00:09:44] Symptoms of MCAS [00:12:08] Hormonal impacts on mast cells. [00:15:42] Long COVID and mast cell activation. [00:20:51] Perfect storm of infections. [00:23:41] Plasmapheresis for mast cell activation. [00:29:04] EMF sensitivity and health effects. [00:30:11] EMF shielding devices and methods. [00:34:44] Fatigue in mast cell activation. Memorable Quotes: "My mission is really to figure out how can we get it to the point where this could be potentially, quote-unquote, cured. " [00:25:16] – Dr. Tania Dempsey "I'm going to help the world, one patient at a time, by giving them this information so they can help themselves." [00:37:11] – Dr. Tania Dempsey Links Mentioned: Mighty Maca Mango: https://drannacabeca.com/products/mighty-maca Connect with Dr. Tania Dempsey: Mast Cell Matters Podcast: https://drtaniadempsey.com/podcast/ Website: https://drtaniadempsey.com/ Instagram: https://www.instagram.com/drtaniadempseymd/ Facebook: https://www.facebook.com/taniadempseymd/ LinkedIn: https://www.linkedin.com/in/taniadempsey/ YouTube: https://www.youtube.com/@DrTaniaDempsey Connect with Dr. Anna Cabeca: Website: https://drannacabeca.com/pages/show Instagram: https://www.instagram.com/thegirlfrienddoctor/ YouTube: https://www.youtube.com/@thegirlfrienddoctor TikTok: https://www.tiktok.com/@drannacabeca Produced by Evolved Podcasting: www.evolvedpodcasting.com
This episode originally aired as #395 on 1/13/24. It's an oldie but goodie so we are sharing it again! What is Aged Garlic Extract (A.G.E.) and how is it different from the garlic we eat? Can this one thing actually lower cholesterol, improve insulin resistance, keep bones strong, boost immunity and detoxification, and prevent dementia? We tend to compartmentalize our bodily systems, but they are all connected and the cardiovascular system is at the head of them all. Learn the science behind how A.G.E. can impact all of our systems, how to take it, how much to take, and what the research actually shows, on this episode of Vitality Radio, where Jared interviews Jim LaValle all about Kyolic Aged Garlic Extract. You'll learn its many benefits and how to use it to improve your overall health. Products:Kyolic Aged Garlic ProductsAdditional Information:#278: The Incredible Benefits of Aged Garlic ExtractLipid tests discussed: NMR LipoProfile® TestCardio IQ®Visit the podcast website here: VitalityRadio.comYou can follow @vitalitynutritionbountiful and @vitalityradio on Instagram, or Vitality Radio and Vitality Nutrition on Facebook. Join us also in the Vitality Radio Podcast Listener Community on Facebook. Shop the products that Jared mentions at vitalitynutrition.com. Let us know your thoughts about this episode using the hashtag #vitalityradio and please rate and review us on Apple Podcasts. Thank you!Just a reminder that this podcast is for educational purposes only. The FDA has not evaluated the podcast. The information is not intended to diagnose, treat, cure, or prevent any disease. The advice given is not intended to replace the advice of your medical professional.
In this insightful episode, Dr. Jill Carnahan sits down with Dr. Amy Proal as they delve into the emerging connections between Bartonella infections and Long Covid, revealing new research that may reshape our understanding of chronic illness. Discover how the MTOR pathway plays a pivotal role in pathogen survival and mitochondrial health, and how drugs like rapamycin could be game-changers in managing these infections. We also explore Mast Cell Activation Syndrome (MCAS) and its links to unresolved infections, offering hope for treatment beyond medication. Key Discussions ① Bartonella and Long Covid:
Struggling with a bloated stomach after eating or chronic abdominal distension? In this episode, I'll explain why dysfunction in three major systems causes bloating and reveal 5 evidence-based microbiome fixes that can help reduce stomach bloating while healing your gut naturally. Start healing with us! Learn more about our virtual clinic: https://drruscio.com/virtual-clinic/ Free downloadable Low FODMAP Diet guide: https://drruscio.com/guides/get-low-fodmap-diet-guide/ Featured products: Elemental Diet: https://store.drruscio.com/products/elemental-heal Triple Therapy Probiotics: https://store.drruscio.com/products/triple-therapy-probiotic Biota Clear Series: https://store.drruscio.com/search?q=biota+clear Biota Dissolve: https://store.drruscio.com/products/biota-dissolve VaguStim: https://vagustim.io/
In this episode, we dive into a two-part story of intrigue starting from a paradigm shift in understanding of T cell biology because of a mouse model of post-measles encephalopathy, to the eventual recognition of the IL-23/17 immune axis. • Intro 0:01 • In this episode 0:12 • Interleukin-17 (IL-17) is a relatively recent discovery 1:34 • The beginning of TH-17 2:20 • Looking at autoimmune encephalopathy: A story of measles 03:30 • 1790's woman with post measles inflammatory process in the brain 10:26 • What is causing post-infection encephalitis? 12:00 • Acute disseminated encephalomyelitis 12:30 • How did we find out the immune system was behind this - The rabies vaccine 13:09 • Similarity between the rabies vaccine and infections like measles 16:04 • T-cell lymphocytes 17:12 • The forgotten thymus 18:00 • What's the function of T-cells? 19:35 • How do you tell T-cells apart? 21:14 • The Human Leukocyte Differentiation Antigens Party 24:05 • The godfather of T-cells 24:45 • The TH-1 and TH-2 axis 27:30 • Experimental Autoimmune Encephalomyelitis model screwed everything up 29:16 • Interferon gamma 32:32 • What's missing? IL-23 surprise 33:40 • IL-17 in the 1990's 36:44 • The world is introduced to TH-17 39:12 • Let's recap what we learned 40:30 • That is the end! 42:30 • Thanks for listening 42:39 We'd love to hear from you! Send your comments/questions to Dr. Brown at rheuminationspodcast@healio.com. Follow us on Twitter @HRheuminations @AdamJBrownMD @HealioRheum. References: Bashyam H. J Exp Med. 2007;doi:10.1084/jem.2042fta Bennetto L, et al. J Neurol Neurosurg Psychiatry. 2004;doi:10.1136/jnnp.2003.034256 Berche P. Presse Med. 2022;doi:10.1016/j.lpm.2022.104149 El-behi M, et al. J Neuroimmune Pharmacol. 2010;doi:10.1007/s11481-009-9188-9 Gooderham MJ, et al. J Eur Acad Dermatol Venereol. 2018;doi:10.1111/jdv.14868 Hawkes JE, et al. J Immunol. 2018;doi:10.4049/jimmunol.1800013 Rogozynski N, et al. Immunol Lett. 2024;doi:10.1016/j.imlet.2024.106870 Sospedra M, et al. Annu Rev Immunol. 2005;doi:10.1146/annurev.immunol.23.021704.115707 Steinman L. Nat Med. 2007;doi:10.1038/nm1551 Disclosures: Brown reports no relevant financial disclosures.