Podcasts about immune

In this episode, I sit down with Dr. Nicole Cain to talk about her integrative, trauma-informed approach to anxiety and mental wellness. We explore how anxiety shows up in the body—through our thoughts, hormones, immune system, and gut—and what it takes to truly heal at the root.Nicole shares insights from her book Panic Proof along with powerful tools like EMDR, hormone testing, and Ayurveda. Whether you're navigating anxiety yourself or supporting someone who is, this conversation is packed with practical, whole-person strategies to find calm and reclaim your mental health.Leave Us A Voice Message! | https://telbee.io/channel/4_b9zzx58wdkuwirqkcxwa/Topics Discussed:What is the root cause of anxiety and how can it be healed naturally?How does gut health affect mental health and anxiety?What is Dr. Nicole Cain's approach to managing anxiety with integrative medicine?What is the connection between hormone imbalances and anxiety symptoms?Sponsored By:Be Well By Kelly Protein Powder & Essentials | Get $10 off your order with PODCAST10 at bewellbykelly.com.AG1 | Get a FREE 1-year supply of Vitamin D3+K2 AND 5 free AG1 Travel Packs with your first subscription at drinkAG1.com/bewell.Jesse & Ben's | Right now, you can visit jesseandbens.com/bewell for a special deal.OneSkin | Visit oneskin.co/BEWELL and use code BEWELL for 15% off your first purchase.Timestamps:00:00:00 - Introduction 00:00:00 – Episode intro with Dr. Nicole Cain00:01:41 – What is anxiety? Root causes explained00:05:49 – Kelly's personal anxiety journey00:09:02 – Understanding the window of tolerance00:10:36 – Anxiety, autonomy, and creative power00:13:22 – Why suppressed emotions intensify anxiety00:14:37 – Dr. Nicole's story of living with anxiety00:19:30 – What is thought anxiety?00:24:32 – Tools to overcome thought anxiety00:26:02 – Endocrine anxiety and stress hormones00:32:21 – Hormonal imbalance, anxiety & HRT00:35:35 – DUTCH testing00:37:21 – Immune system's link to anxiety00:40:34 – Gut-brain axis and mental health00:42:13 – Lifestyle changes for anxiety relief00:43:32 – Dr. Nicole's full intake process00:49:31 – Using Ayurveda and Kapha for anxiety00:51:58 – Exercises to calm anxiety naturally00:57:55 – Brain science: prefrontal cortex vs. lizard brain01:01:55 – Interoception and body awareness01:06:28 – How to become panic proofFurther Listening:Prioritizing Hormonal Health with Dr. Carrie JonesCheck Out Dr. Nicole: InstagramBook - To Shop

Steph talks about identification of gut bacteria that can digest protective mucosal antibodies and Vincent covers a new paper on Zika virus that implicates fetal phagocytes in brain invasion, which may provide insight into the devastating microcephaly outcome of infection during pregnancy. Hosts: Vincent Racaniello, Cindy Leifer, Steph Langel, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become a patron of Immune! Links for this episode MicrobeTV Discord Server Gut bacteria induce mucosal immunodeficiency (Science) Contribution of fetal mononuclear phagocytes to Zika virus neuroinvasion (Cell) TWiV468 discusses Zika and brain slice infection model. Time stamps by Jolene Ramsey. Thanks! Music by Tatami. Immune logo image by Blausen Medical Send your immunology questions and comments to immune@microbe.tv Information on this podcast should not be construed as medical advice.

Cold and Flu Season? Try These 5 Immune-Boosting Foods for Kids!As the weather cools down and winter bugs start circulating, keeping your kids healthy can feel like a full-time job. But here's some good news: one of the most effective ways to support your child's immune system doesn't come from a supplement bottle — it starts in your kitchen.In this episode of the Natural Super Kids Podcast, we're sharing five simple, science-backed food hacks that strengthen your child's immune system naturally. These tips are perfect for busy parents, picky eaters, and families who want to feel empowered when it comes to supporting immunity during winter.Here's what we cover:Why letting garlic sit before cooking can unlock powerful antimicrobial compounds that is beneficial to the immune system.How A2 dairy (from Jersey, Guernsey, sheep or goats) supports gut and immune health and may reduce inflammation.How adding superfood powders into your kid's meals (they won't even notice it's there)  is one of the best ways to boost your child's iron, zinc, and vitamin A levels.Easy ways to use immune-boosting herbs in everyday meals.How probiotic-rich foods support a healthy gut — where 70% of the immune system lives!

BUFFALO, NY - May 23, 2025 – A new #research paper was #published in Volume 16 of Oncotarget on May 19, 2025, titled “Immune-mediated adverse events following atezolizumab and bevacizumab in a multinational Latin American cohort of unresectable hepatocellular carcinoma." The study, led by first authors Leonardo Gomes da Fonseca from Hospital das Clínicas, Universidade de São Paulo, Brazil, and Federico Piñero from Hospital Universitario Austral, Argentina, investigated how patients with advanced liver cancer in Latin America respond to a widely used immunotherapy combination. The researchers found that although a minority of patients developed immune-related side effects, these events did not significantly impact overall survival. Their findings highlight the importance of early recognition and careful management of such side effects in real-world clinical settings. Liver cancer is a leading cause of cancer deaths worldwide, with limited treatment options for patients diagnosed at an advanced stage. Immunotherapy, particularly the combination of atezolizumab and bevacizumab, has become a standard approach. However, these treatments can sometimes trigger the body's immune system to attack healthy organs, leading to what are called immune-related adverse events, or irAEs. Until now, little data existed on how frequently these events occur in Latin American patients and whether they impact treatment outcomes. The researchers followed 99 patients from Argentina, Brazil, Chile, and Colombia, most of whom had cirrhosis or underlying liver disease. They received atezolizumab and bevacizumab for a median duration of six months. The researchers reported that only 18% of the patients experienced immune-related side effects, most commonly affecting the liver (hepatitis) and thyroid (thyroiditis). Most of these cases were mild or moderate, and half of them resolved completely within a month. Only eight patients needed treatment with steroids to control the immune response. Importantly, the occurrence of immune-related side effects did not affect how long patients survived after starting treatment. The median survival was the same—18.5 months—for both those who experienced irAEs and those who did not. This result suggests that while irAEs require careful management, they may not reduce the overall benefits of immunotherapy. Another significant finding was that patients with higher levels of alpha-fetoprotein (AFP), a protein often elevated in liver cancer, were more likely to experience these side effects. This information could help clinicians identify patients who need closer control during treatment. “Notably, baseline alpha-fetoprotein (AFP) values ≥400 ng/ml were significantly associated with the development of irAEs.” The study also points to key differences between clinical trial results and real-world experiences. While clinical trials report higher rates of side effects, this real-world data showed a lower incidence, possibly due to less intensive monitoring or differences in how side effects are documented in everyday practice. In summary, this study highlights that patients require ongoing vigilance and individualized care when treating liver cancer with immunotherapy. It provides valuable information to healthcare providers in Latin America and other regions with similar patient populations, aiming to improve outcomes while minimizing risks. DOI - https://doi.org/10.18632/oncotarget.28721 Correspondence to - Federico Piñero - fpinerof@cas.austral.edu.ar To learn more about Oncotarget, please visit https://www.oncotarget.com. MEDIA@IMPACTJOURNALS.COM

Host: Denise M. Dupras, M.D., Ph.D. Guest: Saad J. Kenderian, M.B., Ch.B. Dr. Saad Kenderian discusses the use of CAR-T cell therapy, a groundbreaking treatment that genetically modifies a patient's T-cells to target and destroy cancer cells, particularly in blood cancers like leukemia and lymphoma. He highlights the importance of identifying eligible patients, monitoring treatment response, and applying genomics to guide the future of personalized cancer immunotherapy. Connect with us and learn more here: https://ce.mayo.edu/online-education/content/mayo-clinic-podcasts 

In today's episode, supported by Camber Pharmaceuticals, we spoke with Kanwarpal S. Kahlon, MD, an associate clinical professor of medicine at the UCLA School of Medicine. In our exclusive interview, Dr Kahlon discussed the significance of the commercial availability of the generic, AB-rated formulations of eltrombopag (Promacta), a bioequivalent medication for the treatment of select patients with severe aplastic anemia and immune thrombocytopenia. He noted how the biosimilar is expected to reduce costs and improve the accessibility of this treatment, potentially enhancing patient adherence. He also explained how it is available in both oral suspension and tablet formulations and that it is well tolerated, with a safety profile similar to that of the original drug.

In this episode, Dr. Adam Rinde welcomes back microbiologist and PolyBio Research Foundation co-founder Dr. Amy Proal. Together, they unravel a framework for understanding chronic illnesses through the lens of persistent infections and their impact on mitochondria, immunity, and neurological health.Dr. Proal shares cutting-edge research linking pathogens like herpesviruses, cytomegalovirus, Epstein-Barr, and even latent parasites to conditions like Alzheimer's, long COVID, chronic fatigue syndrome, POTS, and more. Discover how stealth microbes can disrupt the vagus nerve, hijack mitochondrial energy systems, and weaken immune responses, setting the stage for a cascade of chronic dysfunctions.The conversation dives deep into the role of immune modulation, including promising findings around low-dose rapamycin and its potential to restore immune signaling and combat viral persistence. They also explore diet, metabolic interventions, and new clinical trials shaping the future of treatment.Whether you're a patient, practitioner, or curious mind, this episode offers profound insight into the evolving science of chronic illness and hope for emerging therapies.

In this week's episode we'll learn about how frequent blood donation affects clonal hematopoiesis in older, male blood donors; the effect of immune microenvironment on response to bispecific antibodies in diffuse large B-cell lymphoma; and the feasibility of adding blinatumomab to early consolidation therapy in CD19-positive Ph-negative B-cell acute lymphoblastic lymphoma.Featured ArticlesClonal Hematopoiesis Landscape in Frequent Blood DonorsIntegrative genomic analysis of DLBCL identifies immune environments associated with bispecific antibody responseUpfront Blinatumomab Improves MRD Clearance and Outcome in Adult Ph-negative B-lineage ALL: The GIMEMA LAL2317 Phase 2 Study

Download my free guided meditation audio bundle here: https://thewellnessengineer.com/audiobundle   Protect yourself from harmful EMFs with the Harmoni Pendant. Save up to 50% on Harmoni Pendant here: https://thewellnessengineer.com/harmoni   Did you know that past attempts to manage your weight could have unknowingly triggered internal chaos affecting your today's health and ability to shed pounds? Join me and my guest, Becca Chilczenkowski, a Board Certified Functional Practitioner and Hormone Specialist who helps women escape the exact health traps that she also endured for years, to learn more about how to uncover if your body's defense system is the hidden reason you feel stuck and how to activate your body's incredible deep-cleaning ability for real change.   In this episode you'll learn: ⏰ 02:36 - Becca's history of dieting leading to autoimmune issues  ⏰ 13:40 - How to know if the immune system is behind weight loss resistance  ⏰ 19:10 - The steps in reversing the innate immune system ⏰ 23:35 - The body's magic cleaning system: autophagy ⏰ 27:37 - The first step: liver support ⏰ 30:05 - Step two: Shock the gut! ⏰ 31:10 - Step three: Food and fasting  ⏰ 38:50 - The ONE thing you can do to activate self-healing Check out Becca Chilczenkowski's Bio: Becca Chilczenkowski is a Board Certified Functional Practitioner and Hormone Specialist.  She is the Founder/Co-Owner of FitMom, a leading functional practice helping women heal from chronic health struggles.     She is also a wife, mom of two, recovering exercise addict, stress addict, and her mission is to help women avoid the struggles she endured for so long.  Years of hormone imbalances, uncontrollable weight gain, constipation, bloating, and never getting answers or proper diagnoses from doctors.     She wants to create as many informed consumers and healthy, happy mid-life women as possible.  Becca Chilczenkowski's gift and link: Hormone Factor Guide - Women's Guide To Jumpstarting Your Metabolism and Resetting Your Hormones What is inside: - Quizzes to help you determine which hormonal imbalances you may be struggling with - 21-Day Reset with meal plan and supplement recommendations - Support to help you get on the path to resetting your metabolism, your hormones, adrenals, and the struggling systems making you feel blah.   Click here to get your free Hormone Factor Guide: https://bit.ly/3pD7IGg    Connect with Becca Chilczenkowski: Website: https://fitmomlife.com  Facebook: https://www.facebook.com/fitmomco  Instagram: https://www.instagram.com/thehormonequeen/  YouTube: https://www.youtube.com/@fitmomco    ***** Hi there! I am Jane Hogan, the Wellness Engineer, and the host of Wellness By Design. I spent 30 years designing foundations for buildings until the pain and inflammation of rheumatoid arthritis led me to hang up my hard hat and follow my heart. Now I blend my backgrounds in science and spirituality to teach people how to tap into the power of their mind, body and soul. I help them release pain naturally so they can become the best version of themselves.    Wellness By Design is a show dedicated to helping people achieve wellness not by reacting to the world around them but by intentionally designing a life based on what their own body needs. In this show we explore practices, methods and science that contribute to releasing pain and inflammation naturally.   Learn more at https://thewellnessengineer.com   Would you like to learn how to release pain by creating more peace and calm?  Download my free guided meditation audio bundle here: https://thewellnessengineer.com/audiobundle   Connect with Jane:  Facebook: https://www.facebook.com/JaneHoganHealth/ Instagram: https://www.instagram.com/janehoganhealth  

Cancer—just the word alone can spark fear and anxiety. And today, we're going to talk about it. Fearlessly.In this episode, Dr. Stephen Petteruti discusses the practicalities and pitfalls of common cancer screening methods, specifically for esophageal and colon cancer, for less invasive and safer alternatives like nasal endoscopy and Cologuard. He also shares the profound impact that lifestyle choices, particularly diet, obesity management, and toxin avoidance, can have on reducing cancer risk.Learn actionable tips for nurturing your immune system, the importance of sleep, managing inflammation, and avoiding known carcinogens.Tune in to this episode to gain valuable strategies and insights! Fear, Food & Prevention: The Truth About Cancer, Screening, and Immune Power.Key Points:00:00 Introduction01:04 Fear as a driver in cancer screening01:39 Cancer is largely environmental05:12 Preventative drugs06:17 Carcinogens accumulative effects07:34 Esophageal cancer08:09 Barrett's esophagitis10:12 Serious complications from an EGD14:22 Watch your diet15:18 Colon cancer screening18:25 Cologuard20:05 Two basic kinds of polyps21:28 Prevention mindsetEnjoy the podcast? Subscribe and leave a 5-star review on your favoritePlatforms.Dr. Stephen Petteruti is a leading Functional Medicine Physician dedicated to enhancing vitality by addressing health at a cellular level. Combining the best of conventional medicine with advancements in cellular biology, he offers a patient-centered approach through his practice, Intellectual Medicine 120. A seasoned speaker and educator, he has lectured at prestigious conferences like A4M and ACAM, sharing his expertise on anti-aging. His innovative methods include concierge medicine and non-invasive anti-aging treatments, empowering patients to live longer, healthier lives.Website: www.intellectualmedicine.com  YouTube: https://www.youtube.com/@dr.stephenpetteruti LinkedIn: https://www.linkedin.com/in/drstephenpetteruti/ Instagram: instagram.com/dr.stephenpetteruti Produced by https://www.BroadcastYourAuthority.com#CancerScreening #PreventiveCare #GutHealthDisclaimer:  The content presented in this video reflects the opinions and clinical experience of Dr. Stephen Petteruti and is intended for informational and educational purposes only. It is not medical advice and should not be used as a substitute for professional diagnosis, treatment, or guidance from your personal healthcare provider. Always consult your physician or qualified healthcare professional before making any changes to your health regimen or treatment plan.

Immune thrombotic thrombocytopenic purpura (iTTP) is a rare coagulopathic disorder characterized by immune-mediated thrombocytopenia and microangiopathic hemolytic anemia, that can cause life-threatening thrombosis. Coauthor Allyson M. Pishko, MD, MSCE, of the University of Pennsylvania joins JAMA Associate Editor David Simel, MD, MHS, to discuss the recent review of iTTP published in JAMA. Related Content: Immune Thrombotic Thrombocytopenic Purpura

Immune checkpoint inhibitors are cancer drugs that for many have been a lifeline. Yet they are associated with a range of reactions that really need to be cataloged so they're easier to recognize, some experts argue. Johns Hopkins Kimmel Cancer … Possible impacts of new cancer drugs need to be cataloged, Elizabeth Tracey reports Read More »

What happens to your body during a 3-day fast? In this video, we'll cover the fasting health benefits of both intermittent fasting and extended fasting for 72 hours or longer. I'll also share some expert fasting tips for even more fasting benefits. 0:00 Introduction: Not eating for 3 days?1:02 Intermittent fasting benefits1:44 Extended fasting benefits3:12 Autophagy and fasting 4:22 72-hour fast benefits 4:49 Immune benefits of extended fasting5:36 Fasting tips 6:28 How to break a fastDid you know that insulin resistance is behind most chronic diseases, including many types of cancer? Frequent eating leads to insulin resistance, which blocks cells from getting fuel. Diets involving 5 to 6 small meals daily destroy the metabolism the most!An intermittent fasting plan involving 18 hours of fasting with a 6-hour eating window can provide tremendous health benefits, such as weight loss in the midsection, improved mood, and decreased inflammation. A 24 to 48-hour fast can significantly magnify the benefits of fasting. Extended fasting enables you to deplete the stored glycogen in your liver. You may also notice significant initial water weight loss. During a 1 to 2-day fast, most of your fuel will come from ketones. Your microbes will thrive, and growth hormone will increase, boosting muscle growth and burning fat.Ketones will feed the neurons in the brain, so you may notice improved cognitive function.Extended fasting allows you to get into a state of autophagy, where your body removes damaged cells and proteins and creates new ones. Autophagy also allows you to build new brain cells. A 3-day fast can produce even more benefits! Extended fasting for 72 hours can clean up intracellular pathogens, including Epstein-Barr and herpes viruses. A 3-day fast can stimulate your immune system, protecting you against cancer and autoimmune diseases. You can achieve results similar to stem cell therapy for free!If you're unsure of how to fast and want to make the process as comfortable and beneficial as possible, try these fasting tips for the most fasting benefits:•Coffee and tea are okay during a water fast•Make sure you have enough sea salt•Consume electrolytes like potassium and magnesiumRefeeding can have a negative impact after a 3-day fast. It's best to rebuild your caloric intake slowly. Bone broth is a great option to break your fast. Dr. Eric Berg DC Bio:Dr. Berg, age 60, is a chiropractor who specializes in Healthy Ketosis & Intermittent Fasting. He is the author of the best-selling book The Healthy Keto Plan, and is the Director of Dr. Berg Nutritionals. He no longer practices, but focuses on health education through social media.

In this three-part series, Jonathan Sackier sits down with Richard Conway, rheumatologist, researcher, and educator. Together, they delve into cutting-edge insights on polymyalgia rheumatica, immune ageing, and the future of rheumatology care. 00:22 – Mortality Patterns 08:57 – JAK Inhibitors

From the 2024 Society for Leukocyte Biology meeting, Immune talks with Holger Heine about the discovery of immune recognition of bacterial lipopolysaccharide and innate immunity to organisms within the kingdom Archaea. Hosts: Cindy Leifer and Brianne Barker Guest: Holger Heine Become a patron of Immune! Links for this episode MicrobeTV Discord Server TLR8 recognizes human gut-associated archaeon (Front Immunol) The human archaeome and its relevance for health and disease (FEBS) Structural insights into TLR4 recognition of synthetic LPS mimetics (Nature Comm) Society for Leukocyte Biology Time stamps by Jolene Ramsey. Thanks! Music by Tatami. Logo image by Blausen Medical Send your immunology questions and comments to immune@microbe.tv Information on this podcast should not be construed as medical advice.

Graph Therapeutics combines AI-driven perturbation modeling with multi-omics data to develop targeted therapies for patients with complex immune-mediated diseases who currently lack effective treatment options.

In this monthly Healthy Her segment, host Amelia Phillips answers listener questions. This episode covers the questions: Dotti Thorne: As the weather cools down what supplements do you recommend to boost our immune system? Vanessa Andrew: Every year over winter I gain weight, only to have to work hard in spring to lose it. What are your tips for avoiding winter weight gain or should I just make peace with it? Kim Lord: I’m confused about coconut products, are they good or bad for us? About the host: Amelia Phillips is an exercise, nutrition, parenting and business expert with a career spanning 26 years in health. She's a registered exercise scientist, nutritionist and researcher (with a masters of human nutrition). She is the co-founder of health tech company 12WBT which grew from start-up. After a successful exit, she now runs online programs using biomarkers to help members get a complete snapshot of their health. Amelia had four kids in five years and is dedicated to empowering women to build a life after kids on the foundation of health (mental and physical), connection and purpose. If you have a question for Amelia, reach out via Insta @_amelia_phillips, or email ap@ameliaphillips.com.au Amelia's Inner Vitality Online Program: https://innervitality.ameliaphillips.com.au/ Find out more at www.ameliaphillips.com.au CREDITSHost: Amelia Phillips Audio Producer: Darren RothMusic: Matt Nicholich Production Partner: Nova Entertainment Pty Ltd Healthy Her acknowledges the Traditional Owners of the Land we have recorded this podcast on, the Gadigal people of the Eora Nation. We pay our respects to their Elders past and present and extend that respect to all Aboriginal and Torres Strait Islander cultures. See omnystudio.com/listener for privacy information.See omnystudio.com/listener for privacy information.

Welcome back to today's Friday Review where I'll be breaking down the best of the week!     I'll be sharing specifics on these topics:     Low Micro-Plastic Gum (product review) The Everyday Hero Manifesto (book review) Food Allergens & Immune Cells (research) Omega-3 & Aspirin (research)     For all the details tune in to today's Cabral Concept 3381 – Enjoy the show and let me know what you thought!   - - - For Everything Mentioned In Today's Show: StephenCabral.com/3381 - - - Get a FREE Copy of Dr. Cabral's Book: The Rain Barrel Effect - - - Join the Community & Get Your Questions Answered: CabralSupportGroup.com - - - Dr. Cabral's Most Popular At-Home Lab Tests: > Complete Minerals & Metals Test (Test for mineral imbalances & heavy metal toxicity) - - - > Complete Candida, Metabolic & Vitamins Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Complete Stress, Mood & Metabolism Test (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Complete Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Complete Omega-3 & Inflammation Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels) - - - Get Your Question Answered On An Upcoming HouseCall: StephenCabral.com/askcabral - - - Would You Take 30 Seconds To Rate & Review The Cabral Concept? The best way to help me spread our mission of true natural health is to pass on the good word, and I read and appreciate every review!  

What if the products you use every day—your toothpaste, your shampoo, your food containers—were silently hijacking your hormones, damaging your immune system, and passing that disruption on to future generations? In this explosive conversation, Darin sits down with Dr. Aly Cohen, triple board-certified physician and founder of The Smart Human, to unpack the shocking reality of unregulated chemicals in our homes, food, and water. Together, they explore the science behind endocrine disruption, the failures of U.S. chemical policy, and how simple daily swaps can radically reduce your toxic burden. This episode is not about fear—it's about power. It's about reclaiming your right to live clean.     What You'll Learn in This Episode: 00:00 – Welcome to the show + why this episode matters 01:00 – How a red dog toy changed Dr. Aly's career forever 04:30 – The hidden health hazards in your home right now 06:50 – Endocrine disruptors: the silent chemicals causing massive damage 09:10 – From rheumatology to environmental health warrior 11:15 – Why FDA and EPA aren't protecting your health 13:40 – How "safe exposure levels" are based on outdated science 16:00 – GRAS loopholes: how chemicals are self-approved in the food system 18:20 – “Fragrance” is a legal disguise for 100+ toxic ingredients 20:00 – Immune dysfunction, infertility, cancer—how hormone mimics wreak havoc 23:10 – Her 4 A's Framework: Assess, Avoid, Add, Allow 26:40 – The autoimmune epidemic + the environmental root cause 29:00 – Frozen organic vs. dirty dozen: the smarter grocery strategy 32:00 – Consistency > perfection: why small swaps matter most 34:30 – Dr. Aly's top swaps for cleaning, skincare, and cookware 37:00 – PFAS, microplastics, canned food liners, and takeout wrappers 40:10 – The Progresso Soup study that proved behavior change works 43:00 – How to detox without supplements 46:00 – Teaching detox habits to kids through gamification 49:00 – Your genes aren't your destiny—epigenetics and detox 52:00 – Why we can't wait for regulations to save us 55:00 – What to travel with: filters, skincare, food prep 59:00 – What shocked Dr. Aly the most in her research 1:02:00 – Final thoughts on resilience, power, and your right to clean living     Don't Forget... I just launched my brand new program Superlife Supermind. Visit my website https://superlife.com/ to learn more about how you can get rid of stress, improve sleep and overall health today.     Thank You to Our Sponsors: Shakeology – Shakeology-All in One Nutrition: Get 15% off with code SUPERLIFE at Shakeology.com. Our Place: Toxic-free, durable cookware that supports healthy cooking. Use code DARIN for 10% off at fromourplace.com.     Find More From Dr. Aly Cohen: Website: thesmarthuman.com Instagram: @thesmarthuman Book: Non-Toxic: Guide to Living Healthy in a Chemical World     Connect with Darin Olien: Website: darinolien.com Instagram: @darinolien Book: Fatal Conveniences SuperLife Products & Protocols: superlife.com     Key Takeaway: "It's not about being perfect. It's about becoming aware—and starting to swap out what's hurting you every single day." – Dr. Aly Cohen

In this three-part series, Jonathan Sackier is joined by Rini Chatterjee, clinician, longevity expert, and Founder of Resilience Health. Together, they explore how functional medicine, biohacking, and evolutionary biology can be used to transform modern health care, improve health span, and prevent chronic disease.  Timestamps: 00:00 – Resilience Health's impact 04:30 – Gut–brain connection 12:00 – Immune optimisation   

What if ageing well had less to do with your genes, your skincare routine or the supplements you take ... and more to do with your immune system?Most of us think about immunity as something that only matters when we're fighting off a cold or flu. But actually, it's quietly working behind the scenes every single day shaping how we feel, how we recover and how long we stay well.Our immune health is also constantly evolving and changing over our lifecycle. From birth to our 20s, midlife and beyond our immune system plays a critical role in how we feel, our risk of disease and how well we age.Dr Jenna Macciochi is an immunologist specialising in the intersection of nutrition, movement, mind-body practices and lifestyle with the immune system in health and disease. She's also a brilliant science communicator who has a beautiful way of weaving science with story. In her new book, Immune to Age, Dr Jenna reframes immunity not as a fortress that springs into action, but as a lifelong partner guiding us through the seasons of our lives from the day we're born to the way we age.We dive into:Why inflammation is not just good or badHow your immune system changes with ageWhat to focus on in your 20s, 40s and beyondThe role of inflammation, infection and stress in ageingSupplements like creatine, collagen, taurine, peptides and nootropic mushroomsFollow @dr_jenna_macciochi and preorder the book “Immune to Age”

Parshat Tazria

If you've heard of brain retraining, you've probably heard of Ashok Gupta. He is the founder of the AIR Neuro Immune Hypothesis which explores the root causes of our symptoms, chronic fatigue, pain, anxiety and more and provides a science-based, true healing. If you've ever been told it's all in your head, you can't heal, or if you feel like you've tried everything without the results you so desperately seek, you need to know about Amygdala and Insula Retraining. It's not all in your head, it's in your brain, and nervous system. Ashok is an internationally renowned Speaker, Filmmaker & Health Practitioner, and founder of the Gupta Program, who has dedicated his life to supporting people through chronic illness, and achieving their potential. You can learn more about him by going to his website: https://guptaprogram.com/ or you can connect with him on instagram at https://www.instagram.com/guptaprogram     Additional Resources:

Learn, Understand and Master the LANGUAGE of WOMEN

Wondering how to realistically eat clean and optimize your health amid a busy life? In this special episode, we're joined by nutritionist, speaker, author, and cancer survivor Elissa Goodman. You'll hear a powerful clip from Elissa's masterclass featured in the 40-Day Home Detox, where she shares practical tips for cooking nutrient-dense, clean meals even on your busiest days. Discover Elissa's preferred cooking methods for immune support, her practical thoughts on using frozen veggies, and why avoiding toxins is crucial for health and vitality. Also included is a flashback to Episode 35, where Elissa shares her powerful story of overcoming multiple health diagnoses, including cancer, through transformative dietary and lifestyle changes. Also included is a special replay of Episode 35—first released on May 11, 2021—where Elissa Goodman shares her inspiring story of healing from cancer and chronic illnesses through clean eating and holistic wellbeing. If you're looking for practical detox tips and motivation to reclaim your health, this conversation is a must-listen. Resources Mentioned On This Episode Ready to detox your kitchen and nourish your life? Join the 40-Day Home Detox now to access Elissa's full masterclass plus an exclusive PDF featuring Elissa's go-to brands and products for optimal health. 40-Day Home Detox D-Tox Academy About Elissa Goodman ElissaGoodman.com Cancer Hacks: A Holistic Guide to Overcoming your Fears and Healing Cancer (Amazon affiliate link) About Ruan Living Grounded in the philosophy of Practical Nontoxic Living™, Ruan Living offers flexible ways for you to craft your Ultimate Home Detox™ to help you elevate your health and well-being, one thoughtful choice at a time. Specifically, we're zoned in on environmental influences—easy ones you can control—that can optimize your, and your intergenerational, healthspan and epigenetics through Practical Nontoxic Living™. Rooted in mindfulness over perfection, we guide you with empowering insights to detox your home and body of toxic chemicals, heavy metals, radiation, and stress. Ruan Living offers books, online programs, customized support, and free resources to help you create a home and lifestyle that nurtures healing and thriving. Learn more at www.ruanliving.com. About Sophia Ruan Gushée Sophia Ruan Gushée is the founder of Ruan Living and author of the critically acclaimed bestselling book A to Z of D-Toxing: The Ultimate Guide to Reducing Our Toxic Exposures. Throughout her suite of Ruan Living Offerings, the diversity of Home detox paths that she has created are designed to welcome you to craft your Ultimate Home Detox™—rooted in the philosophy of Practical Nontoxic Living™, which protects your joy and convenience while guiding you to avoid toxicity. Learn more about Sophia here: Sophia Ruan Gushée.

04-16-25 Immune to Any Attack - Pastor Chad Smailes by Glen Ferris Apostolic Church

On this episode of Crazy Wisdom, I, Stewart Alsop, spoke with Neil Davies, creator of the Extelligencer project, about survival strategies in what he calls the “Dark Forest” of modern civilization — a world shaped by cryptographic trust, intelligence-immune system fusion, and the crumbling authority of legacy institutions. We explored how concepts like zero-knowledge proofs could defend against deepening informational warfare, the shift toward tribal "patchwork" societies, and the challenge of building a post-institutional framework for truth-seeking. Listeners can find Neil on Twitter as @sigilante and explore more about his work in the Extelligencer substack.Check out this GPT we trained on the conversation!Timestamps00:00 Introduction of Neil Davies and the Extelligencer project, setting the stage with Dark Forest theory and operational survival concepts.05:00 Expansion on Dark Forest as a metaphor for Internet-age exposure, with examples like scam evolution, parasites, and the vulnerability of modern systems.10:00 Discussion of immune-intelligence fusion, how organisms like anthills and the Portuguese Man o' War blend cognition and defense, leading into memetic immune systems online.15:00 Introduction of cryptographic solutions, the role of signed communications, and the growing importance of cryptographic attestation against sophisticated scams.20:00 Zero-knowledge proofs explained through real-world analogies like buying alcohol, emphasizing minimal information exposure and future-proofing identity verification.25:00 Transition into post-institutional society, collapse of legacy trust structures, exploration of patchwork tribes, DAOs, and portable digital organizations.30:00 Reflection on association vs. hierarchy, the persistence of oligarchies, and the shift from aristocratic governance to manipulated mass democracy.35:00 AI risks discussed, including trapdoored LLMs, epistemic hygiene challenges, and historical examples like gold fulminate booby-traps in alchemical texts.40:00 Controlled information flows, secular religion collapse, questioning sources of authority in a fragmented information landscape.45:00 Origins and evolution of universities, from medieval student-driven models to Humboldt's research-focused institutions, and the absorption by the nation-state.50:00 Financialization of universities, decay of independent scholarship, and imagining future knowledge structures outside corrupted legacy frameworks.Key InsightsThe "Dark Forest" is not just a cosmological metaphor, but a description of modern civilization's hidden dangers. Neil Davies explains that today's world operates like a Dark Forest where exposure — making oneself legible or visible — invites predation. This framework reshapes how individuals and groups must think about security, trust, and survival, particularly in an environment thick with scams, misinformation, and parasitic actors accelerated by the Internet.Immune function and intelligence function have fused in both biological and societal contexts. Davies draws a parallel between decentralized organisms like anthills and modern human society, suggesting that intelligence and immunity are inseparable functions in highly interconnected systems. This fusion means that detecting threats, maintaining identity, and deciding what to incorporate or reject is now an active, continuous cognitive and social process.Cryptographic tools are becoming essential for basic trust and survival. With the rise of scams that mimic legitimate authority figures and institutions, Davies highlights how cryptographic attestation — and eventually more sophisticated tools like zero-knowledge proofs — will become fundamental. Without cryptographically verifiable communication, distinguishing real demands from predatory scams may soon become impossible, especially as AI-generated deception grows more convincing.Institutions are hollowing out, but will not disappear entirely. Rather than a sudden collapse, Davies envisions a future where legacy institutions like universities, corporations, and governments persist as "zombie" entities — still exerting influence but increasingly irrelevant to new forms of social organization. Meanwhile, smaller, nimble "patchwork" tribes and digital-first associations will become more central to human coordination and identity.Modern universities have drifted far from their original purpose and structure. Tracing the history from medieval student guilds to Humboldt's 19th-century research universities, Davies notes that today's universities are heavily compromised by state agendas, mass democracy, and financialization. True inquiry and intellectual aloofness — once core to the ideal of the university — now require entirely new, post-institutional structures to be viable.Artificial intelligence amplifies both opportunity and epistemic risk. Davies warns that large language models (LLMs) mainly recombine existing information rather than generate truly novel insights. Moreover, they can be trapdoored or poisoned at the data level, introducing dangerous, invisible vulnerabilities. This creates a new kind of "Dark Forest" risk: users must assume that any received information may carry unseen threats or distortions.There is no longer a reliable central authority for epistemic trust. In a fragmented world where Wikipedia is compromised, traditional media is polarized, and even scientific institutions are politicized, Davies asserts that we must return to "epistemic hygiene." This means independently verifying knowledge where possible and treating all claims — even from AI — with skepticism. The burden of truth-validation increasingly falls on individuals and their trusted, cryptographically verifiable networks.

They discuss practical strategies for rebuilding trust in your body, the critical role of understanding your core values, and how to find the right support — whether through programs like Rheum to Thrive or events like the Virtual Sjögren's Summit. Together, they show how education, advocacy, and mindset shifts can help patients move from fear to confidence in managing their immune health.Episode at a glance:Sjogren's and MCAS 101: what is Sjogren's and MCAS?Dr. Kara Wada's personal journey: Sjögren's and mast cell activation syndrome (MCAS) and how it shaped her mission to empower patients.Understanding "Immune Confidence": learning to trust your body again after autoimmune and allergic disease diagnoses.The importance of patient advocacy and education: how Dr. Wada supports patients across multiple states through educational visits.Healthcare system issues: why are complex patients being given the short end of the stick, and what are some creative solutions?Upcoming events and opportunities: the Virtual Sjögren's Summit and Cheryl's evolving focus with Rheum to THRIVE.Finding balance between personal life and professional advocacy while living with chronic illness.Medical disclaimer: All content found on Arthritis Life public channels was created for generalized informational purposes only. The content is not intended to be a substitute for professional medical advice, diagnosis, or treatment.Episode SponsorsRheum to THRIVE, an online course and support program Cheryl created to help people with rheumatic disease go from overwhelmed, confused and alone to confident, supported and connected. See all the details and join the program or waitlist now! 

Send us a textHave you ever been told that birth control is your only option for endometriosis—and that you should just learn to live with the pain? You are NOT alone. On today's episode of The Endo Belly Girl Podcast, I cut through the common myths and bring you the deeper conversation you deserve. If you've ever wondered “why is this happening to me?” or want to get to the root of your endo, this episode is for you.In today's episode, you'll hear:The real truth behind common endo myths, including:“Birth control fixes endo”“Endo is just a hormone problem”“If your labs are normal, you're fine”Why hormone imbalance is almost always a symptom, not the root causeWhy the conventional approach to endo often falls short—and how functional nutrition can fill in the gapsWhy there isn't just one root cause of endometriosis, but rather a tangled web (just like the roots of a weed!)An overview of the top 6 factors that can drive endo, including:Immune system dysfunctionChronic inflammationNutrient deficienciesBlood sugar imbalanceUnderlying infections (like SIBO, candida, or parasites)Chronic stress & nervous system dysregulationInsights from expert Dr. Lara Briden and why treating endo isn't as simple as shutting down your hormonesHow functional testing (beyond “normal” labs) can reveal hidden causes of symptomsThe importance of tracking your patterns—meals, symptoms, stress, cycle—and asking yourself “why is this happening?” instead of “what can I take?”Actionable first steps to start addressing the roots of your endometriosis and where to find deeper supportResources Mentioned:Ep. 5: What Is Endometriosis Really?Ep. 21: Blood Sugar: The Key to Hormonal BalanceEp. 63: Top 6 Nutrients for Endo WarriorsEp. 82: Histamine and EndometriosisEp. 83: Normal Labs, No Answers?Ready to dig deeper into your endo journey and get personalized support? Book a free 30-minute consultation. Join the upcoming free workshop: The Endo Relief Blueprint Subscribe to The Endo Belly Girl Podcast: Apple | SpotifyConnect w/ Alyssa: Instagram Website Work w/ Alyssa: Free Endo Diet Guide Work with me 1:1 Join the EndoWellness Initiative Learn more about AlyssaDisclaimer: This podcast is for educational purposes only. This may not be the best fit for you and your personal situation. It shall not be construed as medical advice. The information and education provided here is not intended or implied to supplement or replace professional medical treatment, advice, and/or diagnosis. Always check with your own physician or medical professional before trying or implementing any information read here.

DHEA was first identified in 1931 by Dr. Adolf Butenandt, who was awarded the Nobel Prize for Chemistry in 1939. Frequently called “the anti-aging hormone”, DHEA is a base for more than 50 hormones that are smaller or more specific carbon chain molecules in human biochemistry. As a precursor for all estrogenic and androgenic hormones, humans make DHEA naturally from birth.It's now well established that chronic stress leads to an out-pouring of cortisol and with that, a gradual depletion of DHEA. DHEA is a prohormone – a natural building block for hormones our bodies make. Over time, this hormonal imbalance can lead to brain fog, thinning bones, weight gain, low sex drive and poor Immune function.Maintaining proper DHEA levels in the body is important to your overall health and may lead to Increased energy, enhanced mood and focus, sound sleep, and better letting skin.Guest: Joining us today is Hugh Woodward, He is the President of Health2Go, Inc the makers of Twist 25 DHEA cream. Hugh is a subject matter expert on DHEA dedicating nearly 2 decades of his life studying the medical research about it, and starting a company to research, develop the safest most effective DHEA supplement that can be made and distributing it.In 2007 Mr. Woodward started Health2Go, Inc. to research and develop leading edge anti-aging and wellness products and bring them to people conveniently and cost effectively.Quality matters when supplementing with DHEA.Twist 25 DHEA Cream puts exactly what the body makes naturally – bioidentical DHEA -in the skin, where the body processes DHEA.  As a base building block for hormones, DHEA gives the body a key foundation it uses to make hormones, (especially the androgens our feel-good hormones.)Visit Twist25.com to learn more and order online. Or call 888-489-4782 that's888-489-4782. Look your best feel your best with Twist 25 DHEA creamthat's twist25.com Listeners can save 15% OFF using the code: forever at checkout.Helpful Articles 

This AANEM podcast features Dr. Joome Suh, a neurologist and neuromuscular specialist at Brigham and Women's Hospital, interviewed by neuromuscular fellow Dr. Nadia Khalil. They discuss HMG-CoA reductase immune-mediated necrotizing myopathy (HMGCR IMNM), a rare autoimmune muscle disease often associated with statin use. The discussion covers clinical presentation, epidemiologic considerations, histopathologic findings, and treatment approaches, with special focus on Dr. Suh's recent research published in Muscle and Nerve with co-author Dr. Anthony Amato. Their study found that patients receiving maintenance IVIG as part of their regimen were more likely to have a normal CK at 6 months and the daily prednisone-equivalent was lower. A sub-group analysis suggested IVIG as monotherapy is effective.

Immune talks with David Peterson and Kim Klonowski from the University of Georgia about their careers, their People, parasites, and plagues podcast, placental malaria immunity, and and how interferons in the thymus affect T cell repertoire selection. Hosts: Vincent Racaniello, Cindy Leifer, Steph Langel, and Brianne Barker Guests: David Peterson and Kim Klonowski Subscribe (free): Apple Podcasts, RSS, email Become a patron of Immune! Links for this episode MicrobeTV Discord Server People, parasites, and plagues podcast Placental malaria and circumsporozoite protein-specific immunity (Trends in Parasitology) Sterile production of interferons in the thymus affects T cell repertoire selection (Science Immunology) Dickson Despommier's book People Parasites and Plowshares Time stamps by Jolene Ramsey. Thanks! Music by Tatami. Immune logo image by Blausen Medical Send your immunology questions and comments to immune@microbe.tv Information on this podcast should not be construed as medical advice.

Featuring slide presentations and related discussion from Dr Hanny Al-Samkari, Dr James B Bussel and Prof Nichola Cooper, including the following topics: Introduction (0:00) Clinical Manifestations and Initial Management of Immune Thrombocytopenia (ITP) — Dr Al-Samkari (10:24) Second- and Later-Line Therapies for ITP — Dr Bussel (1:00:51) Tolerability and Other Practical Considerations with Available Treatment Strategies for Persistent/Chronic ITP — Prof Cooper (1:28:08) CME information and select publications

Welcome back to the Dr. Kinney Show! This week, I'm thrilled to be joined by Dr. Anna Sitkoff, a licensed naturopathic doctor and expert in medicinal mushrooms. As the co-founder and Chief Science Officer of Lucidum Medicinals, Anna brings an incredible depth of knowledge and passion for evidence-based natural therapies that support immune function, hormonal balance, and full-body wellness.In this episode, we take a deep dive into the science and magic of mushrooms—how they work in the body, the difference between types, and how to make sure you're choosing the right supplements for your health goals. Whether you're curious about immune support, gut health, adrenal recovery, or fertility, mushrooms might just be the solution you didn't know you needed.In Today's Episode We Discuss:How Anna became a leading voice in the world of medicinal mushroomsThe powerful immune-modulating effects of mushrooms like reishi, cordyceps, and turkey tailHow mushrooms support gut health, hormonal balance, and adrenal functionThe difference between fruiting bodies and mycelium—and why that mattersWhen and how to take mushrooms for the best resultsThe surprising benefits of mushrooms for fertility, lung health, brain function, and moreWhy not all mushroom supplements are created equal—and what to look forAnna's go-to mushrooms for viral load reduction, long COVID, and chronic fatigueWhether you're a practitioner or just mushroom-curious, Anna breaks it all down in a way that's both deeply scientific and totally approachable. You'll walk away with a whole new appreciation for these powerful fungi—and how to use them to support your health naturally.Connect with Dr. Anna Sitkoff:Website: www.drannasitkoff.comInstagram: @drannasitkoffLinkedIn: Dr. Anna SitkoffLucidum Medicinals: www.lucidummedicinals.comDiscount for Listeners: Use code DRKINNEY for 20% off Lucidum Medicinals productsDiscount Code: POD25 -  https://optimal-harmony-with-dr-kinney.myshopify.com

Dr Hanny Al-Samkari from Massachusetts General Hospital in Boston, Dr James B Bussel from Weill Cornell School of Medicine in New York, New York, and Prof Nichola Cooper from Hammersmith Hospital Campus in London, United Kingdom, share expert perspectives on the diagnosis of and optimal management strategies for immune thrombocytopenia. CME information and select publications here.

BUFFALO, NY - April 28, 2025 – A new #research paper was #published in Oncotarget, Volume 16, on April 24, 2025, titled “PD-L1 and FOXP3 expression in high-grade squamous intraepithelial lesions of the anogenital region." Researchers Humberto Carvalho Carneiro, Rodrigo de Andrade Natal, José Vassallo and Fernando Augusto Soares from the Instituto D'Or de Pesquisa e Ensino and Rede D'Or studied early tissue changes caused by human papillomavirus (HPV) in the anal, vulvar, and penile regions. They found that high-grade pre-cancer lesions triggered stronger immune responses and showed higher levels of two immune-related markers, PD-L1 and FOXP3. These findings are important because they help explain how some HPV-related lesions progress to cancer while others heal on their own. High-risk HPV is known to cause several types of anogenital cancers. Before these cancers appear, the virus often leads to abnormal tissue changes known as high-grade squamous intraepithelial lesions. Many of these lesions disappear without treatment, but some become cancer—especially in people with weakened immune systems. This study explored how immune activity may play a role in this progression. The researchers examined tissue from 157 patients—95 males and 55 females—with either high-grade or low-grade HPV-related lesions. They found that T-regulatory cells, marked by the FOXP3 protein, were more common in high-grade lesions. These immune cells are known to suppress immune responses, which can allow infected or abnormal cells to grow. The team also found higher expression of PD-L1, a protein that helps cells evade immune detection, particularly in inflammatory immune cells. "Dense inflammatory infiltrates and high counts of FOXP3+ cells were significantly more frequent in patients with HSILs than in those with LSILsHR (p = 0.04 and 0.02, respectively). HSILs also exhibited higher PD-L1 expression (padj < 0.01 and < 0.01 for the SP142 and 22C3 clones, respectively), based on the Poisson generalized linear model.” These findings suggest that HPV may begin avoiding the immune system early in infection, even before cancer develops. The combination of high FOXP3 and PD-L1 levels may create a protective environment for infected cells, making them harder for the body to eliminate. This immune evasion may allow the lesions to remain and, over time, become cancerous. The study also compared patients with and without HIV to assess whether immune health influenced the results. While those with compromised immune systems had more extensive lesions, PD-L1 and FOXP3 expression was also found in patients with healthy immune systems. This evidence shows that immune evasion by HPV can happen regardless of a person's immune status. Understanding how PD-L1 and FOXP3 function in early HPV-related lesions may help clinicians predict which lesions are more likely to become cancer. These insights could lead to new strategies for monitoring, treating, or preventing HPV-related precancerous lesions and cancer in the anogenital region. The study highlights how early immune system changes can play a key role in the development of HPV-related cancers. DOI - https://doi.org/10.18632/oncotarget.28715 Correspondence to - Humberto Carvalho Carneiro - humberto.carneiro@rededor.com.br Video short - https://www.youtube.com/watch?v=6d8G8TUbgYc Subscribe for free publication alerts from Oncotarget - https://www.oncotarget.com/subscribe/ To learn more about Oncotarget, please visit https://www.oncotarget.com and connect with us: Facebook - https://www.facebook.com/Oncotarget/ X - https://twitter.com/oncotarget Instagram - https://www.instagram.com/oncotargetjrnl/ YouTube - https://www.youtube.com/@OncotargetJournal LinkedIn - https://www.linkedin.com/company/oncotarget Pinterest - https://www.pinterest.com/oncotarget/ Reddit - https://www.reddit.com/user/Oncotarget/ Spotify - https://open.spotify.com/show/0gRwT6BqYWJzxzmjPJwtVh MEDIA@IMPACTJOURNALS.COM

Join us for a fascinating conversation with Dr. Livnat Jerby, an Assistant Professor of Genetics at Stanford University, Chan Zuckerberg Biohub Investigator, and Paul Allen Distinguished Investigator. In this episode, Dr. Jerby shares how her lab is decoding and engineering immune circuits to create next-generation cell therapies, drawing on high-throughput technologies and computational modeling. We explore how multicellular programs shape disease and immunity, revisit her work on immune evasion during her time at the Broad Institute, and discuss the future of synthetic immune systems and interdisciplinary science. Hosted by Emma Chen.

In this episode, we discuss the gut-immune axis and Small Intestinal Fungal Overgrowth (SIFO), with a mechanistic focus on immune activation and epithelial barrier disruption. We detail contributing factors to and symptoms of SIFO. We further discuss the anatomical positioning and immunological functions of mast cells within the lamina propria, highlighting mast cell activation syndrome, while detailing how SIFO and SIBO can serve as upstream triggers for mast cell activation.Topics:1. The Gut-Immune Axis and Mast Cells - The intestinal epithelium forms the innermost selective barrier, coated in a protective mucus layer.- Immediately beneath lies the lamina propria, rich in immune cells including mast cells. 2. Mast Cells in the Lamina Propria - Mast cells are positioned near nerves, capillaries, lymphatics, and epithelial cells within the lamina propria.- Their anatomical location enables rapid immune surveillance and inflammatory response.- Mast cell granules store histamine and more. 3. Mast Cell Mediators - Histamine: Biogenic amine, inflammatory signaling.- Tryptase: A serine protease.- Cytokines and lipid mediators also released upon activation. 4. Mast Cell Activation Syndrome (MCAS) - Systemic: skin, respiratory tract, cardiovascular system, nervous system, and more.- The gastrointestinal tract.- Common triggers for mast cell activation. 5. Transition to Small Intestinal Fungal Overgrowth (SIFO) - Overgrowth of fungal organisms, often candida species, within the small intestine.- Contributing factors including hypochlorhydria, slowed motility, immune suppression, disrupted bacterial populations.- Overlap: SIFO, SIBO  6. Hypochlorhydria and the Stomach's Defense Role - Parietal cells secrete hydrochloric acid (HCl) and intrinsic factor.- HCl denatures proteins and sterilizes ingested pathogens.- Chief cells secrete pepsinogen, which becomes pepsin in acidic conditions to digest proteins.- Consequences of Reduced Gastric Acidity  7. The Role of Intestinal Motility - Enteric nervous system (ENS), myenteric and submucosal plexuses.- Coordinated contractions preventing stasis and microbial overgrowth. 8. Common Symptoms of SIFO and clinical overlap with SIBO 9. Candida and Fungal Pathophysiology in the Gut - Yeast form, regulated by microbial competition and immune defenses.- Hyphal transformation.- Degrade the mucus layer, disrupt epithelial integrity, trigger inflammation. 10. Secretory IgA and Mucosal Defense - Chronic stress, immune dysfunction, dysbiosis can lower sIgA levels and weaken mucosal immunity. 11. SIFO, SIBO, and Mast Cell Activation  12. Conclusion  - Root cause approach, multi-factorial Thanks for tuning in!Get Chloe's Book Today! "⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠75 Gut-Healing Strategies & Biohacks⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠" Follow Chloe on Instagram ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@synthesisofwellness⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow Chloe on TikTok @chloe_c_porterVisit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠synthesisofwellness.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ to purchase products, subscribe to our mailing list, and more!

VLOG April 25 US v Sean Combs 11 am https://www.amazon.com/dp/B0DHP7YF19US v Luigi Mangione 1 pm https://books.google.com/books/about/Luigi_Mangione_Lone_Wolf.htmlOff til Tues, Harvey Weinstein https://matthewrussellleeicp.substack.com/p/courtroom-extra-harvey-weinsteinJail delay denied, Wael Hana - and Gold Bar Bob?IMF answers but UN bans Press, UNWRA not immune?

Immune system? Who is she! But genuinely.. who.. is she? Dr Edward Roper is here dropping unmatched pathology knowledge and unparalleled insight into the immune system! We are thrilled to have him on board and learn from the best! Tune in!

On this episode Lara and Vyanka talk to Dr David Bick from Genomics England all about genetics analysis of immunological conditions and the newborn screening program. This is ImmunoTea: Your Immunology Podcast, presented by Dr Lara Dungan and Dr Vyanka Redenbaugh. This is the show where we tell you all about the most exciting research going on in the world of immunology. So grab a cup of tea, sit down and relax and we'll fill you in. Contact us at ImmunoTeaPodcast@gmail.com or @ImmunoTea on twitter. Hosted on Acast. See acast.com/privacy for more information.

Do you ever feel like you are reacting negatively to some of the foods that you eat? You may be. In this episode of the podcast, we discuss the different types of adverse reactions to food that people can experience. We cover:The difference between a food allergy and an intoleranceThe different types of food intolerances Immune vs. non-immune mediated intolerancesWhy food sensitivity testing is inaccurateListen to my previous podcast on food allergies with Dr. David Stukus here. Interested in working with me? Schedule a Discovery Call here. Enjoying the show or have a questions about a particular topic? Send us a message here. Support the show

SHOW NOTES:   In Podcast Episode 319, “Even God's Faithful Aren't Immune to Betrayal,” Kim discusses the sting of betrayal. Whether the betrayal is in a personal relationship, or someone in authority betrayed you, the pain can be life-changing. Yet, when the betrayal is in a church or ministerial context, there are added layers of hurt. Join Kim as she explores two stories from scripture that describe betrayal. Hang on to the end, and she prays for all those hurting from the effects of betrayal.   Our focal passage for this episode is 2 Kings 5:20-27 with 22 as the focal verse:   22 “Yes,” Gehazi said, “but my master has sent me to tell you that two young prophets from the hill country of Ephraim have just arrived. He would like 75 pounds of silver and two sets of clothing to give to them.”     WEEKLY ENGAGEMENT FEATURE:   When have you experienced betrayal?   Additional Resources and Scriptures:   Judas - 47 But even as Jesus said this, a crowd approached, led by Judas, one of the twelve disciples. Judas walked over to Jesus to greet him with a kiss. 48 But Jesus said, “Judas, would you betray the Son of Man with a kiss?” (Luke 22:47-48) EMAIL — encouragingothersinlovingjesus@gmail.com TWITTER - https://twitter.com/EOinLovingJesus INSTAGRAM -  https://www.instagram.com/encouragingothersinlovingjesus/ “Encouraging Others in Loving Jesus” YouTube Channel: Check it out at https://www.youtube.com/@EncouragingOthersInLovingJesus   I WANT TO BEGIN A PERSONAL RELATIONSHIP WITH JESUS CHRIST.   RESOURCES USED FOR BOOK OF 1 & 2 Kings PODCASTS: “The Wiersbe Bible Commentary: The Complete Old Testament OT in One Volume” “Christ-Centered Exposition: Exalting Jesus in 1 & 2 Kings” by Tony Merida “The Tony Evans Bible Commentary: Advancing God's Kingdom Agenda” “Life Application Study Bible” “The Swindoll Study Bible: NLT” by Charles R. Swindoll Holman Illustrated Bible Dictionary “The Baker Illustrated Bible Background Commentary” by J. Scott Duvall and J. Daniel Hays (Editors) Expositor's Bible Commentary (Abridged Edition): Old Testament, 2004, by Kenneth L. Barker, John R. Kohlenberger, III.     "Encouraging Others in Loving Jesus" Facebook Group:   Our Facebook Group is devoted to providing a place for us to encourage each other through all the seasons of life. Follow the provided link to request admittance into “Encouraging Others in Loving Jesus”—https://www.facebook.com/groups/encouragingothersinlovingjesus/ Feel free to invite others who will be good encouragers and/or need encouragement to follow Jesus.   This podcast is hosted by Kim Smith, a small town Country Girl who left her comfort zone to follow Jesus in a big City World. Now, she wants to use God's Word and lessons from her faith journey to encourage others in loving Jesus.   In each episode, Kim will share insights regarding a portion of God's Word and challenge listeners to apply the lessons to their daily lives.   If you want to grow in your faith and learn how to encourage others in loving Jesus, subscribe and commit to prayerfully listening each week.   Remember, “It's Always a Trust & Obey Kinda Day!”   If you have questions or comments or would like to learn more about how to follow Jesus, please email Kim at EncouragingOthersinLovingJesus@gmail.com.     National Suicide & Crisis Lifeline   988   https://988lifeline.org/   Reference: Unless otherwise indicated, all Scripture quotations are taken from the Tyndale House Publishers. Holy Bible: New Living Translation. Wheaton, Ill: Tyndale House Publishers, 2004.   Podcast recorded through Cleanfeed and edited through GarageBand. The soundtrack, entitled “Outlaw John McShane” was obtained from Pixabay.         The HIDDEN Episodes:  If you can't access episodes 1-50 on your podcast app (the podcast was then entitled "A Country Girl in a City World - Loving Jesus"), you can get all the content at my Podbean site at https://acountrygirlinacityworldlovingjesus.podbean.com/  

Listen to 109 Future Now Show Good news if you live in the California or the Pacific Northwest - The governrment early warning earthquake network is now up and operational, giving you precious seconds before you feel the tremors!  Get the app “My Shake” if you want to be extra ready!  If you haven’t received all your Covid stimulus checks, Bobby has some tax advice for you, and DOGE with Palantir has some advice for the IRS, as they plan a mega API for the service, one network to service us all.. Welcome back Katy, now an ‘astronaut’ via Blue Origin’s Shepard rocket, along with a group of female friends.  A new approach to cancer therapy looks promising, tricking the body to have a rejection immune response to cancerous tumors..and it appears that certain fungi can help us ‘mine’ gold with minimal environmental impact, and provide a new way to extract the precious metal from remote asteroids. Our fav AI co-hosts, Larry and Mary tackle this topic as well as a strange UAP incident in the Ukraine.  Back at home it appears that OpenAI is planning to start a new social network to compete with X, Facebook, etc. Lots to share this week, enjoy! Fungus metabolizing gold

In this episode of Ageless Energy, we explore how women over 40 can naturally build a stronger, more resilient immune system. From daily habits and nutrition to stress management and supplements, Drew breaks down the most effective, science-backed ways to protect your health year-round. Discover what really works (and what doesn't), and walk away with practical tools to support your immunity — without overwhelm or gimmicks.

This episode is presented by Create A Video – As the deadline approaches for people to get REAL IDs, the pressure on the North Carolina DMV is building. Officials say they have made improvements. But residents are still reporting massive lines, long wait times, and an inability to book online appointments. Subscribe to the podcast at: https://ThePetePod.com/ All the links to Pete's Prep are free: https://patreon.com/petekalinershow Media Bias Check: If you choose to subscribe, get 15% off here! Advertising and Booking inquiries: Pete@ThePeteKalinerShow.com Get exclusive content here!: https://thepetekalinershow.com/See omnystudio.com/listener for privacy information.

From the 2024 Society for Leukocyte Biology meeting, Immune talks with Amy Hise about her career in science, her current research using mouse models for investigating fungal immunity and navigating the challenges of being a mom in science. Hosts: Cindy Leifer and Brianne Barker Guest: Amy Hise MicrobeTV Discord Server Mouse model for testing drugs to treat Candida fungal infection Inflammasomes in Aspergillosis Society for Leukocyte Biology Subscribe (free): Apple Podcasts, RSS, email Become a patron of Immune! Music by Tatami. Logo image by Blausen Medical Send your immunology questions and comments to immune@microbe.tv Content in this podcast should not be construed as medical advice.

Maximizing absorption of supplements is important for optimizing health and our budget! Many companies are innovating on bioavailability and nobody is more cutting edge than Terry Naturally. On this episode of Vitality Radio, Jared invites Dr. Lexi Loch to the show to break down their GammaSorb technology for enhanced nutrient absorption. They discuss how it works and why it's important, and they delve into several of the products they are offering with GammaSorb. These products include Red Ginseng, Lactoferrin, Propolis, PEA, and Ivy Leaf Extract, covering men's and women's health, energy, immune support, pain management, and respiratory support.Terry Naturally Products:Red GinsengLactoferrin & Propolis ExtractPEABronchial Clear - Ivy Leaf ExtractVisit the podcast website here: VitalityRadio.comYou can follow @vitalitynutritionbountiful and @vitalityradio on Instagram, or Vitality Radio and Vitality Nutrition on Facebook. Join us also in the Vitality Radio Podcast Listener Community on Facebook. Shop the products that Jared mentions at vitalitynutrition.com. Let us know your thoughts about this episode using the hashtag #vitalityradio and please rate and review us on Apple Podcasts. Thank you!Just a reminder that this podcast is for educational purposes only. The FDA has not evaluated the podcast. The information is not intended to diagnose, treat, cure, or prevent any disease. The advice given is not intended to replace the advice of your medical professional.

Story at-a-glance Beta-glucans are natural compounds found in foods like oats, mushrooms and barley that significantly enhance immune function by activating dendritic cells These compounds help manage allergies by training your immune system to respond appropriately to allergens without overreacting, reducing symptoms like sneezing and itching Beta-glucans serve as effective adjuvants in allergy treatments, improving the body's antibody production and enhancing the efficacy of immunotherapy Research shows beta-glucans fight infections by stimulating immune cells and have impressive anticancer properties, shrinking tumors by up to 95% in studies You can easily incorporate beta-glucans into your diet through organic oatmeal, shiitake mushrooms, seaweed and organic rye and wheat

Policy questions and growth risks are likely to persist in the aftermath of the Trump administration's upcoming tariffs. Our CIO and Chief U.S. Equity Strategist Mike Wilson outlines how to seek investments that might mitigate the fallout.Read more insights from Morgan Stanley. ----- Transcript -----Welcome to Thoughts on the Market. I'm Mike Wilson, Morgan Stanley's CIO and Chief U.S. Equity Strategist. Today on the podcast – our views on tariffs and the implications for equity markets. It's Monday, March 31st at 11:30am in New York. So let's get after it. Over the past few weeks, tariffs have moved front and center for equity investors. While the reciprocal tariff announcement expected on April 2nd should offer some incremental clarity on tariff rates and countries or products in scope, we view it as a maximalist starting point ahead of bilateral negotiations as opposed to a clearing event. This means policy uncertainty and growth risks are likely to persist for at least several more months, even if it marks a short-term low for sentiment and stock prices. In the baseline for April 2nd, our policy strategists see the administration focusing on a continued ramp higher in the tariff rate on China – while product-specific tariffs on Europe, Mexico and Canada could see some de-escalation based on the USMCA signed during Trump's first term. Additional tariffs on multiple Asia economies and products are also possible. Timing is another consideration. The administration has said it plans to announce some tariffs for implementation on April 2nd, while others are to be implemented later, signaling a path for negotiations. However, this is a low conviction view given the amount of latitude the President has on this issue. We don't think this baseline scenario prevents upside progress at the index level – as an "off ramp" for Mexico and Canada would help to counter some of the risk from moderately higher China tariffs. Furthermore, product level tariffs on the EU and certain Asia economies, like Vietnam, are likely to be more impactful on a sector basis. Having said that, the S&P 500 upside is likely capped at 5800-5900 in the near term – even if we get a less onerous than expected announcement. Such an outcome would likely bring no immediate additional increase in the tariff rate on China; more modest or targeted tariffs on EU products than our base case; an extended USMCA exemption for Mexico and Canada; and very narrow tariffs on other Asia economies. No matter what the outcome is on Wednesday, we think new highs for the S&P 500 are out of the question in the first half of the year; unless there is a clear reacceleration in earnings revisions breadth, something we believe is very unlikely until the third or fourth quarter.Conversely, to get a sustained break of the low end of our first half range, we would need to see a more severe April 2nd tariff outcome than our base case and a meaningful deterioration in the hard economic data, especially labor markets. This is perhaps the outcome the market was starting to price on Friday and this morning. Looking at the stock level, companies that can mitigate the risk of tariffs are likely to outperform. Key strategies here include the ability to raise price, currency hedging, redirecting products to markets without tariffs, inventory stockpiling and diversifying supply chains geographically. All these strategies involve trade-offs or costs, but those companies that can do it effectively should see better performance. In short, it's typically companies with scale and strong negotiating power with its suppliers and customers. This all leads us back to large cap quality as the key factor to focus on when picking stocks. At the sector level, Capital Goods is well positioned given its stronger pricing power; while consumer discretionary goods appears to be in the weakest position. Bottom line, stay up the quality and size curve with a bias toward companies with good mitigation strategies. And see our research for more details. Thanks for listening. If you enjoy the podcast, leave us a review wherever you listen and share Thoughts on the Market with a friend or colleague today.