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A look at Inflammatory Bowel Disease (IBD), more specifically the two main forms of IBD which are Ulcerative Colitis and Crohn's Disease, going through each condition as well as looking at the differences between Ulcerative Colitis and Crohn's disease. Includes the signs and symptoms of each, including extraintestinal manifestations of inflammatory bowel disease, as well as differences in the histology. PDFs available at: https://rhesusmedicine.com/pages/gastroenterologyConsider subscribing (if you found any of the info useful!): https://www.youtube.com/channel/UCRks8wB6vgz0E7buP0L_5RQ?sub_confirmation=1Buy Us A Coffee!: https://www.buymeacoffee.com/rhesusmedicineTimestamps:0:00 What is Inflammatory Bowel Disease?0:15 Ulcerative Colitis and Crohn's Disease Epidemiology1:08 Signs and Symptoms of Inflammatory Bowel Disease / Signs and Symptoms of Ulcerative Colitis and Crohn's Disease3:19 Extraintestinal Manifestations of Inflammatory Bowel Disease4:48 Inflammatory Bowel Disease Pathology5:07 Risk Factors for Ulcerative Colitis and Crohn's Disease / Risk Factors of Inflammatory Bowel Disease5:47 Diagnosis of Ulcerative Colitis and Crohn's Disease / Inflammatory Bowel Disease Diagnosis6:51 Inflammatory Bowel Disease Histology / Ulcerative Colitis v Crohn's Disease Histology7:52 Treatment of Inflammatory Bowel Disease / Ulcerative Colitis and Crohn's Disease TreatmentLINK TO SOCIAL MEDIA: https://www.instagram.com/rhesusmedicine/ReferencesCrohn's & Colitis Foundation (2019) Updated IBD Factbook. Crohn's & Colitis Foundation. Available at: https://www.Crohn'scolitisfoundation.org/sites/default/files/2019-02/Updated%20IBD%20Factbook.pdfWalfish, A.E. and Ching Companioni, R.A. (2023) ‘Overview of inflammatory bowel disease', MSD Manual Professional Edition. Merck & Co., Inc. Available at: https://www.msdmanuals.com/professional/gastrointestinal-disorders/inflammatory-bowel-disease-ibd/overview-of-inflammatory-bowel-diseaseWaugh, N., Cummins, E., Royle, P. et al. (2013) Comparison of Ulcerative Colitis, Crohn's disease, irritable bowel syndrome and coeliac disease, in Faecal calprotectin testing for differentiating amongst inflammatory and non-inflammatory bowel diseases: systematic review and economic evaluation. Southampton: NIHR Journals Library. Available at: https://www.ncbi.nlm.nih.gov/books/NBK261307/Disclaimer: Please remember this video and all content from Rhesus Medicine is for educational and entertainment purposes only and is not a guide to diagnose or to treat any form of condition. The content is not to be used to guide clinical practice and is not medical advice. Please consult a healthcare professional for medical advice.
Faecal transplant, also known as faecal microbiota transplantation or FMT, is the transfer of stool from a healthy donor to a patient with a disease. The idea is to restore the balance of bacteria in the gut, which can be disrupted by factors such as antibiotics, diet, or infection but it could potentially help with a range of problems from irritable bowel syndrome to Alzheimer's. Why is faecal transplant used? How does faecal transplant work? How is faecal transplant performed? What are the risks of faecal transplant? In under 3 minutes, we answer your questions! To listen to the last episodes, you can click here: Could Britain ever rejoin the EU? What 5 foods can improve brain performance? What is pandemic skip? A podcast written and realised by Joseph Chance. First broadcast: 10/8/2023 Learn more about your ad choices. Visit megaphone.fm/adchoices
For this Vet Times Extra podcast, Paul Imrie is joined by RCVS advanced practitioner in small animal practice Richard Sanderson and professional services vet for IDEXX Carole MacColl to discuss faecal antigen testing. SPONSORED Parasites pose a serious threat to pets and people. But prevention alone may not be 100% effective. Updated industry guidelines now recommend intestinal parasite testing at least once a year, regardless of deworming. Combine your preventives with Faecal Dx antigen testing, and parasites don't stand a chance. Faecal Dx antigen testing offers early, accurate detection of the most common intestinal parasites, even in well cats and dogs. Learn more at https://www.idexx.co.uk/en-gb/veterinary/reference-laboratories/fecal-testing/fecal-dx-antigen-test/?utm_source=vet_times&utm_medium=podcast&utm_campaign=rlb_fecaldx_2025 The views and opinions in this recorded conversation expressed by the guest interviewee are the guest interviewee's own and do not necessarily reflect the views of IDEXX. Richard Sanderson, BVSc, CertAVP(SAP), MRCVS, is an RCVS advanced practitioner in small animal practice and director of Peninsula Vet Referrals. He graduated from the University of Liverpool in 2009. An advocate for independent veterinary practice, he founded Sanderson Vet in 2016. This started as a mobile vet and has developed into a 24-hour first opinion clinic. Already accepting a wide range of referrals, he formalised their referral services and opened Peninsula Vet Referrals, which focuses on offering “Affordable experience and accessible expertise”, aiming to make referrals more affordable and easier to access. Carole MacColl BVMS, PGCert, VetEd FHEA, MRCVS graduated from the University of Glasgow in 2011, and gained experience in first opinion practice before undertaking a rotating internship with a focus on emergency and critical care. She spent time as an ECC clinician in referral hospitals throughout Australia and the UK, before a role as a senior veterinarian in the RVC's first opinion teaching hospital. Carole joined IDEXX as a professional services veterinarian covering the south of the UK in 2021.
Can bacteria-free, sterile faecal filtrate match conventional faecal microbiota transplantation for recurrent C difficile infection? Dina Kao (University of Alberta) unpacks a landmark multicentre trial that tested this hypothesis, and we discuss what it tells us about the role of living organisms in the therapeutic effects of microbiota-based therapies.Click here to read the full article: https://www.thelancet.com/journals/langas/article/PIIS2468-1253(25)00190-6/fulltextContinue this conversation on social! Follow us today at... https://bsky.app/profile/lancetgastrohep.bsky.social https://www.linkedin.com/company/langastro/ https://instagram.com/thelancetgroup https://facebook.com/thelancetmedicaljournal https://youtube.com/thelancettv
Today, we're speaking to Dr Rob Perry, who is a Gastroenterology Clinical Research Fellow based at Imperial College London.Title of paper: Evaluating the Role of Faecal Calprotectin in Older AdultsAvailable at: https://doi.org/10.3399/BJGP.2025.0169There is considerable uncertainty surrounding the use of FC as a diagnostic test in older adults, with varying suggestions in guidelines and a lack of data in the wider literature. This study investigates the performance of FC in older adults (≥50 years), compared to a younger cohort, with a view to guide its correct use in a primary care setting. These data suggest that FC is a sensitive test for IBD and organic gastrointestinal pathology in both groups. However, concerns remain over its PPV and specificity, particularly in older adults, and it should not be used if colorectal cancer is suspected.Transcript This transcript was generated using AI and has not been reviewed for accuracy. Please be aware it may contain errors or omissions.Speaker A00:00:00.880 - 00:00:49.180Hello and welcome to BJGP Interviews. I'm Nada Khan and I'm one of the Associate Editors of the bjgp. Thanks for taking the time today to listen to this podcast. Today we're speaking to Dr.Rob Perry, who is a gastroenterology Clinical Research Fellow based at Imperial College London. We're here to talk about the paper he's recently published here in the BJGP titled Evaluating the Role of Fecal Calprotectin in Older Adults.So thanks, Rob, for joining me here to talk about your work.And I guess I just really want to preface this by saying that a lot has changed in the last few years just in terms of testing for inflammatory bowel disease and bowel cancer in general practice. But I wonder if you could just talk us through this, some of the different guidelines and why you wanted to do this study.Speaker B00:00:49.660 - 00:02:24.450Oh, yes, thank you for having me.Firstly, and the rationale for the study is that, you know, consultations for gastrointestinal symptoms make up a large number of consultations in primary care. I think the figures around 10%.And whilst fecal cow protection is an increasingly well established test for differentiating between inflammatory bowel disease and functional or other gastrointestinal or non inflammatory gastrointestinal diseases, its role in older adults is far less well established.With varying guidelines for clinicians in primary care, the NICE guidelines make no specific mention, for example, of age, other than that calprotectin should not be used where age is considered a risk factor in the context of certain symptoms. For suspicion of cancer, the BSG guidelines on IBD use a cutoff of 40, above which they suggest calprotectin is not used.The something called the NICE York Fecal cow protectant care pathway suggests an age cut above 60, which is a NICE endorsed pathway. So there's some uncertainty there in the literature about which cutoff should be used for fecal cow protectin.And the reason any cutoff is suggested is because data has previously shown that calprotectin lacks sensitivity for diagnosing colorectal cancer.And as age is considered a risk factor for colorectal cancer, guidelines normally mandate earlier endoscopic evaluation of patients with GI symptoms in older age groups.Speaker A00:02:24.530 - 00:02:39.170And can you just talk us through briefly what you did here? So you looked at patients referred for a colonoscopy at one single centre, so at Imperial College Healthcare Trust.But just talk us through...
This podcast summarises the article Pre-operative feeding effects on post-anaesthetic colic and faecal output in horses by Ana Lopes, Ella Aitkin, and Luis Filipe Louro.
A Gluten Free PodcastEpisode 195My guest on today's episode is paediatric gastroenterologist, physician-scientist and the new director for The Center for Celiac Research and Treatment at Mass General for Children, Dr Maureen Leonard. We'll talk about Dr. Leonard's own coeliac disease diagnosis, the CDGEMM study, the gut microbiome, refractory coeliac disease and much more. We'll talk about: * Maureen's newly appointed position of director for The Center for Celiac Research and Treatment at Mass General for Children, succeeding Dr Alessio Fasano * Maureen's history of working alongside Dr Fasano and their ongoing work relationship * Mission for the The Center for Celiac Research and Treatment at Mass General for Children and its history * Dr Leonard's coeliac disease coinciding in her medical training* How Dr Leonard's coeliac disease has influenced her work in coeliac disease research by bringing empathy to her patients and study participants * The unique need when you have coeliac disease to announce your disease and your gluten free requirements * The aim of the Celiac Disease Microbiome and Metabolic Study (CDGEMM) and what Dr Lenoard and the insights the team have gained so far* Environmental factors contributing to coeliac disease activating in individuals * Analysing changes in the microbiome within stool samples prior to coeliac disease onset * Understanding the onset of coeliac disease in order to discover possible prevention methods * Precision medicine and biomarkers in relation to coeliac disease * Use of prebiotics and probiotics for management of coeliac disease * Persistent symptoms and damage in adults and children with coeliac disease despite adherence to a strict gluten free diet * Research in mucosal healing in children with coeliac disease * Defining ‘non-responsive' or ‘refractory' coeliac disease and the current management strategies in place for this condition * Defining the gut microbiome and how its effected in people with coeliac disease* How the gut microbiome can influence the immune system, intestinal barrier integrity, inflammation, gluten metabolism and more * Alterations in the gut microbiome being seen in cohort of children prior to coeliac disease diagnoses * Faecal transplants and coeliac disease* Defining gluten ataxia * Collaboration amongst The Center for Celiac Research and Treatment at Mass General for Children and other organisations in the US and around the world * Biggest question for Dr. Leonard within coeliac disease research currently * Dr. Leonard's advice for parents of children newly diagnosed with coeliac disease * Story of one child's coeliac disease diagnosis and the changes Are you looking for a low cost business, that is easy to run and has a high return on investment? OMG! Decadent Donuts wants you! Join this creative, inclusive and rapidly expanding business today. Apply here: https://omgdecadentdonuts.com/opportunity/ Thanks to our sponsor Happy Tummies! Happy Tummies is a one-stop-shop for allergen-friendly and gluten free products and also stocking their very own brand - Free From Family Co. Click here to have our discount code GFFAMILY automatically applied & save 10% off Free From Family Co products! Celiac Cruise - a 100% gluten free vacation cruise is setting sail on two Australian cruises in 2026: one to the South Pacific and the other to New Zealand. There'll of course be awesome 100% gluten free food onboard, heaps of fun stuff to do, educational talks and a community of people who understand each other. Buy your tickets here & see ya onboard gluten free fam!
In this episode of For Pet's Sake, Mark from Bella+Duke talks to Charlotte, head of clinical administration at Wormcount, about parasite prevention, faecal testing, and why targeted deworming is better than blanket treatment. Learn how to spot signs of worm infestations, why chemical dewormers don't provide long-term protection, and how PCR testing is revolutionizing parasite detection for pets. Charlotte also discusses zoonotic risks, the environmental impact of over-deworming, and the importance of routine testing for dogs of different lifestyles. If you're a pet owner looking to safeguard your dog's health, prevent resistant parasites, and understand modern parasite management, this episode is packed with essential insights.
For more information on SCOPS visit www.scops.org.ukFor our podcast disclaimer see here - scops.org.uk/podcasts/Host: Ben Eagle Co-host: Nerys WrightGuests: Rebecca Mearns, Olly Matthews, Robert Spink.Make sure to subscribe so you don't miss upcoming episodes on parasite control, diagnostics, and sustainable sheep health.This episode is supported by: Boehringer Ingelheim; Elanco; Norbrook; Zoetis
Faecal matter has well and truly hit the fan. People are low on trades already, but then in the space of one round, CARNAGE! Patto and Daneo help you navigate through all the carnage in this episode, as well as VC and C options for Round 19.
GP and training programme director Dr Pipin Singh provides tips on when to use FIT tests, how to adhere to guidelines on their use, and discusses the need for clear protocols around referrals and safety netting to avoid delayed cancer diagnosis. This podcast aims to help healthcare professionals to recall which test results are significant within the context of community testing and within GP management of symptomatic patients. It also provides pointers from NICE guidelines on when to use FIT testing in patients of varying ages, and aims to help GPs to confront challenges such as dealing with false positives and handling referrals while waiting for FIT testing results. Dr Singh stresses the importance of clear protocols around referrals and safety netting.You can access the website version of this podcast on MIMS Learning to make notes for your appraisal. MIMS Learning offers hundreds of hours of CPD for healthcare professionals, along with a handy CPD organiser.Please note: this podcast is presented by medical editors and discusses educational content written or presented by doctors, nurses and other healthcare professionals on the MIMS Learning website and at live events.Further learning on MIMS LearningColorectal cancer: clinical reviewGlobal trends in gastrointestinal cancersRectal bleeding - red flag symptomsPancreatic cancer - red flag symptomsUnintentional weight loss - red flag symptoms Hosted on Acast. See acast.com/privacy for more information.
Faecal transplant, also known as faecal microbiota transplantation or FMT, is the transfer of stool from a healthy donor to a patient with a disease. The idea is to restore the balance of bacteria in the gut, which can be disrupted by factors such as antibiotics, diet, or infection but it could potentially help with a range of problems from irritable bowel syndrome to Alzheimer's. Why is faecal transplant used? How does faecal transplant work? How is faecal transplant performed? What are the risks of faecal transplant? In under 3 minutes, we answer your questions! To listen to the last episodes, you can click here: Could Britain ever rejoin the EU? What 5 foods can improve brain performance? What is pandemic skip? A podcast written and realised by Joseph Chance. First broadcast: 10/8/2023 Learn more about your ad choices. Visit megaphone.fm/adchoices
A Cold Open, Sausage Haggling, Neil Discovers The Map Exists Again, An Old Lady Gets Bullied, Bish Bash Bosh, We Are Dropping At Tilted Towers, Its Star Of Stage And Screen Jack Lyttle With Some Thrilling Exposition, Noughts And Ogres, A Stat Check and much much more!Bluesky:https://bsky.app/profile/dungeonsanddheads.bsky.socialInstagram:https://www.instagram.com/dungeonsanddheads/Discord:https://discord.gg/brB2Agj65VPatreon:https://www.patreon.com/c/DungeonsAndDHeadsYouTube:https://www.youtube.com/@DungeonsAndDheads Hosted on Acast. See acast.com/privacy for more information.
This week is hosted by Philippa & QuentinWe talk about what has happened in Ambridge, in The Archers so far this weekA short midweek round up of The Archers SO FAR focusing on Sunday, Monday & Tuesday episodes up to 11/2/25.Join us for our LIVE online PATREON event: https://www.patreon.com/AllAboutTheArchersOr you can BUY US A COFFEE here: buymeacoffee.com/allaboutthearchersYou can buy our MERCH here: https://www.redbubble.com/people/aboutthearchers/shopDo join our FACEBOOK Group: https://www.facebook.com/groups/1127587031446013/ You can also watch this on YOUTUBE: https://www.youtube.com/@AllAboutTheArchers-vv8jz/videosThe ArchersWe are on BLUESEKY!: https://bsky.app/profile/allaboutthearchers.bsky.socialAmbridgeBBCRadio4#Brookfield #TheArchers #AllAboutTheArchers #radio4 #bbcradio #bbcradio4 #ambridge #soapopera #borchester #bridgefarm #podcast Hosted on Acast. See acast.com/privacy for more information.
In this episode of the UEG Talks conversation between Maria Vehreschild and Pradeep Mundre, we delve into the complexities of the faecal microbiome and the role of faecal microbiota transplantation (FMT) in treating various diseases, particularly C. difficile infections and inflammatory bowel disease (IBD). The discussion covers the historical context of FMT, its mechanisms of action, current treatment guidelines, safety considerations, and the various delivery methods. The conversation also emphasises the need for further research and the importance of professional standards in FMT practices.
Craig Fowler and Robert Borthwick chat through the wreckage of another Scottish Premiership weekend, including Stuart Kettlewell walking out of Motherwell, question marks over Jimmy Thelin's management, the powerful running of Hearts' forward pair, Cyriel Dessers being the weirdest player (... ever?), and some dodgy refereeing in the Highlands. Today's podcast is sponsored by AG1. Head to https://drinkag1.com/terrace to take advantage of the special offer. Learn more about your ad choices. Visit podcastchoices.com/adchoices
In this episode, Jonathan Sackier sits down with David Wan to discuss the latest advances in colorectal cancer screening, the importance of high-quality colonoscopy, and the emerging role of AI in polyp detection. Timestamps: (00:00)-Introduction (01:45)-Linking neuroscience and gastroenterology (05:16)-The role of the microbiome in disease (7:44)-Unusual clinical cases (13:52)-Colorectal cancer screening (21:47)-Virtual colonoscopy (23:03)-Faecal calprotectin (25:11)-How to ensure a high-quality colonoscopy? (30:36)-Inpatient gastrointestinal care (34:47)-Variceal bleeding (36:30)-New horizons in gastroenterology (39:53)-Wan's three wishes for healthcare
Jack welcomes Ricky back to the show to talk about the state of Spurs right now. Faecal burgling analogies contained within. Support this show http://supporter.acast.com/ruletheroost. Hosted on Acast. See acast.com/privacy for more information.
Get access to our clinical podcast series with our 30% off IVECCS Special. Get case support from our team at specialists in our Specialist Support Space. Does anyone else feel a bit powerless in those acute diarrhoea consults since we've learned that we shouldn't give metronidazole? Your client has come to you for a solution, and you want to help, but there's nothing you can give them that will really help that much. Or is there? Our bonus episode for day three of our IVECCS 2024 highlights series might give you that magic pill you've been looking for… poop! Dr. James Oldeschulte is well-acquainted with treating acute diarrhoea as an experienced ER vet, and in this conversation, he shares some freshly published data that highlights the efficacy and clarifies the practicalities of using psyllium fibre and faecal transplants in the treatment of acute diarrhoea in veterinary patients. Sign up for our free weekly newsletter to hear about my favourite 3 lessons I learnt in that week from making the podcasts.
Send us a Text Message.Following on from the last episode of the podcast, as promised this is part 2 with Rachel Jessey from Benourised. We continue and expand on the short conversation we had at the end of the last episode on faecal implant, Rachel has so much knowledge and this is a really interesting topic. We also talk about the circadian rhythm and how we can reset this rhythm which supports the natural absorption of vitamin D, sleep, digestion and more. I explain what I put into practice during my recent holiday and what the impact this has had , listen to this episode of the podcast to find out more. Rachel talks about the benefit of natural light thinking about the full spectrum of light, sunrise and sunset. Rachel and I talk about the different severities of chronic conditions and how we can support and meet patients where they are in their journey, and what benefits this can have. We touch upon the benefit of red light and will have a part 3 to this podcast to discuss this in more detail. This is another podcast filled with lots of information, I really appreciate Rachel joining me. As always thank you for listening to the podcast #onedayatatime Links from this episode: Rachel's details: https://www.benourisehed.co.uk/Email:rachel@benourished.co.ukJack Ruse https://jackkruse.com/Alexander Marakovsky https://www.longdom.org/open-access/the-industry-originated-probiotic-bacteria-role-in-covid19-60345.htmlDocumentary: Hack Your Health: The Secrets of Your Gut https://www.netflix.com/title/81436688 My Links:Long Covid clinic -Dr Binita Kane & Julie Taylor; Email: info@thelongcovidclinic.co.uk for more information Linktree:https://linktr.ee/joulestXhttps://twitter.com/julieTa58407536Facebook page:https://www.facebook.com/livingwithlongcovid/Instagram:https://www.instagram.com/julie_livingwithlongcovidPlanners:https://amzn.eu/d/9v9MP4vReturn to work planner:https://amzn.eu/d/1QVK8zn Well being planner:https://amzn.eu/d/a1Safxc
Join The Kernels as they dive into Doug Liman's 2024 burly bouncer reboot: 'Road House.Revelling in remakes, name nomenclature, and coffee shop carnage - The Kernels share their likes, dislikes, ratings & even treat you to an original song, AND a unique game where they create a movie trailer. Enjoy you buoyant bouncers!Thanks for popping by. We hope you enjoy The Podcorn Kernel Podcast. Please get in touch with any praise, criticism, feedback or advice.Compliments will be greeted with kindness. Criticism will be catered to with carnage. Contact us at : thepodcornkernels@gmail.com or find us on us on the following social platforms:Instagram: thepodcornkernelsThreads: thepodcornkernelsTwitter: @podcornkernelsWebsite: thepodcornkernels.co.ukTikTok: @thepodcornkernels
In his weekly clinical update, Dr. Griffin discusses RSV vaccination recommendations and revisions to guidelines before reviewing the recent statistics on SARS-CoV-2 infection, data suggesting that individuals with high HLA-DQA2 expression (MHC class II) are better at preventing the onset of a sustained viral infection, how moderate coffee intake can reduce risk of COVID-19 severity but cannabis use resulted in more severe disease but reduced risk of mortality, where to find PEMGARDA, if statin use prevented severe COVID-19, the benefit of administering nirmatrelvir and ritonavir after 5 days, convalescent plasma, what do when healthcare workers succumb to SARS-CoV-2 infection, if fecal microbiota transplants aid in recovery from COVID-19, and the definition of characteristics and clinical patterns for the diagnosis of long COVID. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode CDC ACIP for RSV (CDC) This respiratory virus season everyone age 75 and older receive the RSV vaccine (CDC Newsroom) Revised RSV vaccine recommendations (CIDRAP) COVID-19 national trend (CDC) COVID-19 deaths (CDC) Local and systemic response dynamics to SARS-CoV-2 infection (Nature) Drink more coffee, reduces risk for SARS-C0V-2 infection (Cell & Bioscience) Cannabis, tobacco…smoking in general NOT good for preventing COVID-19 (JAMA Network OPEN) Do older versions of the COVID-19 vaccine still provide any protection (JAMA Internal Medicine) Where to get pemgarda (Pemgarda) CDC Quarantine guidelines (CDC) Early phase of SARs-CoV-2 infection (COVID.gov) NIH COVID-19 treatment guidelines (NIH) Infectious Disease Society guidelines for treatment and management (ID Society) Adjuvant statin therapy reduces SARS-CoV-2 mortality (American Journal of Medicine) Nirmatrelvir and ritonavir beyond 5 days of symptom onset improved the multiple organ dysfunction in severe COVID-19 patient (BMC Infectious Disease) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What do when your heathcare provider is infected with SARS-CoV-2 (CDC) Managing healthcare staffing shortages (CDC) Steroids, dexamethasone at the right time (OFID) Anticoagulation guidelines (hematology.org) Faecal microbtiota transplantation cures sleep disturbance in post-acute COVID-19 syndrome (Clinical Gastroenterology and Hepatology) Long COVID defined by patient phenotype (CIDRAP) Three distinct symptom-based post-COVID condition phenotypes (JID) Contribute to our Floating Doctors fundraiser Letters read on TWiV 1126 Dr. Griffin's COVID treatment summary (pdf) Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Dr Kurtis Budden, from the Immune Health Program, The University of Newcastle and Hunter Medical Research Institute, Newcastle, NSW, Australia and Professor Philip Hansbro who is also a conjoint there and the Director of the Centenary Institute and University of Technology Sydney Centre for Inflammation, Sydney, NSW, Australia, on the paper "Faecal microbial transfer and complex carbohydrates mediate protection against COPD" published in paper copy in Gut in May 2024. Please subscribe to the Gut podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/3UOTwqS) or Spotify (https://spoti.fi/3Ifxq9p).
Eat Your Greens with Dr. Black | plant-based nutrition for the whole family
Text Dr. Black your questions or comments.In episode 11 of Eat Your Greens with Dr. Black, listeners head to college to learn about the microbiome and its vital role in maintaining overall health. Dr. Black is joined by Dr. Micaela Vargas from the Department of Biology at Texas State University, and they discuss the complex and fascinating aspects of the microorganisms that live in our bodies, particularly our gut. The extensive effects of a healthy microbiome are outlined, from helping to prevent serious diseases like heart disease and cancer, to aiding digestion, regulating blood sugar, and potentially slowing aging. Listen in as Dr. Black and Dr. Vargas explore the impact of lifestyle factors such as diet, sleep, and exercise on the gut microbiome. The episode concludes with practical tips on how to nurture and support a healthy microbiome.Recipe for Dr. Black's breakfast smoothieConnect with Dr. Vargas: https://www.linkedin.com/in/micaelavargasphd/ Links to research articles The Human Microbiome Project Reaches Conclusion The origins of gut microbiome research in Europe: From Escherich to Nissle Current understanding of the human microbiome Association between antibiotics and gut microbiome dysbiosis in children: systematic review and meta-analysis Specific gut microbiome signatures and the associated pro-inflamatory functions are linked to pediatric allergy and acquisition of immune tolerance Faecal microbiota transplantation halts progression of human new-onset type 1 diabetes in a randomised controlled trial Short-Chain Fatty-Acid-Producing Bacteria: Key Components of the Human Gut Microbiota Gut Microbiota: An Important Link between Western Diet and Chronic Diseases Anticancer EffectsIf you enjoyed this episode, please take a moment to rate it, leave a review, and most importantly, share it with a friend! For my free guide to Living a Plant-Forward Life, visit the show website and subscribe! eatgreenswithdrblack.com For resources related to a plant-based diet or if you struggle to afford healthy food for your family, please go to eatgreenswithdrblack.com/resources.You can contact Dr. Black at dr.black@eatgreenswithdrblack.comI am happy to answer general questions related to the information presented on this podcast. Be advised that I will never offer specific medical advice via this website, even if your child is an established patient in my practice. If you have concerns about your child's health or growth, please contact their doctor.Thanks for listening and don't forget to Eat Your Greens!
A fundamental basic of ruminant nutrition – energy density of feeds – is covered in this latest Rumen Room Podcast. Expressed as Megajoules of Metabolisable Energy per kilogram of dry matter (MJME/kgDM), energy density is an important driver of animal productivity and profitability. In a down to earth, practical “gumboot level” manner, Dr Charlotte Westwood explores the basics of MJME as a concept and covers how feed testing laboratories measure MJME. How we use MJME values of a feed on farm on a day to day basis is explained. The strengths and possible limitations with the use of MJME in our day to day farm-level decisions is discussed. Don't be put off by what is often thought to be a rather "dry" topic of MJME - actually, it's a straightforward concept - we're sure you'll learn a lot from this latest podcast! Here's where to find the various sections within the MJME podcast, below: 2.02 Outline of this MJME podcast 3.40 What is “energy”? 6.30 Defining Megajoules and Metabolisable Energy 7.50 Megajoules compared to Megacalories – what's the difference? 10.25 What is gross energy and why might we be interested? 14.25 Why ruminants can't use all of gross energy in feeds for useful things 15.10 Faecal energy – what a waste! (#1) 16.10 Digestible energy 17.25 Methane – what a waste! (#2) 18.10 Finally arriving at the MJME number…. How this is calculated 19.00 How different feeds change energy losses as methane 21.00 Measuring MJME – inside the sheep 23.00 Feed testing laboratories estimates of MJME 25.40 Using the digestibility value to calculate MJME 26.20 NIRS technology - digestibility and MJME 31.15 Strengths and weaknesses of MJME as a measure of feed quality – an overview 32.00 Typical MJME values of feed 34.40 Valuing our feeds on a cents per MJME basis – a simple task on farm! Valuing a bale of pasture baleage on an MJME basis as an example 38.00 Using MJME as part of your feed budgeting – MJME demand vs. MJME supply. A 30kg liveweight lamb as an example 40.30 Limitations of MJME as an indicator of suitability of a feed for animals 41.30 MJME is a calculated measure only! 42.00 MJME doesn't tell us about all of the other interesting stuff in feeds 44.10 Summing up the MJME topic
Colorectal cancer is the fourth most common type of cancer in the UK, with over 40,000 new cases each year. The positive predictive value of Faecal immunochemical testing (FIT) far exceeds that of symptoms and makes FIT an important tool for triaging patients with symptoms suggestive of colorectal cancer to the right diagnostic pathway. In this podcast Dr Thomas Round, a GP and EKU Clinical Lead, talks to Dr Kevin Barrett, a GP in Hertfordshire with a special interest in gastroenterology, about faecal immunochemical testing in patients with signs or symptoms of suspected colorectal cancer (CRC)
Faecal transplant, also known as faecal microbiota transplantation or FMT, is the transfer of stool from a healthy donor to a patient with a disease. The idea is to restore the balance of bacteria in the gut, which can be disrupted by factors such as antibiotics, diet, or infection but it could potentially help with a range of problems from irritable bowel syndrome to Alzheimer's. Why is faecal transplant used? How does faecal transplant work? How is faecal transplant performed? What are the risks of faecal transplant? In under 3 minutes, we answer your questions! To listen to the last episodes, you can click here: Could Britain ever rejoin the EU? What 5 foods can improve brain performance? What is pandemic skip? A podcast written and realised by Joseph Chance. In partnership with upday UK. First broadcast: 10/08/2023 Learn more about your ad choices. Visit megaphone.fm/adchoices
Welcome to another podcast exploring management of bowel dysfunction! Alison Hainsworth asks a panel of experts - Julie Cornish, Liliana Bordeianou and Emily Hoile - to help us to understand how we can look after our patients with faecal incontinence. We look at treatments - ranging from conservative measures to surgical intervention. We aim to offer practical advice as to how we can best serve our patients! Registration for ICS 2023 Toronto is now open at www.ics.org/2023/register The ICS annual meeting is the must-attend, multidisciplinary event for clinical and research scientists interested in: Urology Urogynaecology Female and functional urology Gynaecology Bowel dysfunction Neurourology Pure and applied science Physiotherapy Nursing Geriatrics The ICS 2023 Toronto conference fosters collaboration between all disciplines involved in continence care.
Faecal incontinence affects one in 25 women in postpartum and today, Claire shares her experience. She takes us briefly through her labour and birth and details the confronting realisation that she had no control of her anal sphincter. Thanks to a women's health physiotherapist who demanded horizontal rest - essential for all new mothers! - pelvic floor exercises and dietary changes, Claire recovered by six weeks. She emphasises how important it is to share her story because she had never heard of it happening before and wondered if it was her new reality; a challenging prospect at a very vulnerable time. See omnystudio.com/listener for privacy information.
In this episode, we talk to Mr James Bailey, a Colorectal Research Fellow from the Nottingham Colorectal Service. Paper: Sociodemographic Variations in the Uptake of Faecal Immunochemical Tests in Primary CareAvailable at: https://doi.org/10.3399/BJGP.2023.0033FIT is increasingly used to triage patients with symptoms suggestive of colorectal cancer but variations in use by demographics, ethnicity and socioeconomic status are unknown. We show, in a large regional dataset, that male patients, patients under 65 years, the most deprived patients and ethnic minority groups are less likely to return a FIT sample. It is important that strategies are developed to ensure patients with these protected characteristics are not disadvantaged with the increasing usage of FIT to prioritise urgency of investigations.
For more information on SCOPS visit www.scops.org.ukFor our podcast disclaimer see here - scops.org.uk/podcasts/Today on the podcast we're talking about practical options for performing wormer treatment checks and faecal egg counts. What are the major monitoring tools that are available? When and how often should you be performing wormer treatments in the first place? What's the difference between a good and a bad faecal egg count sample? And, what does resistance really mean? These are just some of the questions that we'll be tackling. Host: Ben EagleCo-host: Lesley StubbingsGuests: Rebecca Mearns (Senior Veterinary Advisor at Biobest) and Anna Hawke (farming near Salisbury).
Our latest episode features guest speaker Dr Ginny Dodunski who joins Rumen Room host Dr Charlotte Westwood for a chat about all things internal parasites. As a New Zealand-based veterinarian and self proclaimed “gumboot parasitologist”, Ginny requires little introduction to most kiwis involved in farming. With a background in veterinary practice, farm consultancy and more recently, working part time with Wormwise, Ginny joins us to cover a range of topics relating to internal parasite management in sheep and cattle. Given the concerning scale of resistance by internal parasites to our range of anthelmintic (drench) products, Ginny steps us through a range of down to earth, practical recommendations to managing internal parasites – including the important role for top quality nutrition for maternal and young stock. Anyone who is involved in managing young stock should tune in - there will be some practical tips and tricks for everyone. Have a scroll (below) through the content for our latest episode featuring Ginny Dodunski. 0.50 Ginny's background and how her passion for all things animal health, and how her journey working with internal parasites began. 6.05 The timeline of New Zealand resistance since the days of effective anthelmintics 7.00 The cost of internal parasites (including resistance issues) to the New Zealand pastoral industries - and at the level of individual farms 8.40 The novel drenches, Zolvix™ Plus (monepantel and abamectin) and Startect® (derquantel and abamectin) help uncover the true cost of internal parasite resistance in lambs 9.50 Picking up sub-clinical internal parasite challenges (or not!) – especially when other autumn health challenges are occurring 12.10 Who to talk to if you suspect internal parasite resistance issues at your place 13.45 Is my drench working or not? Faecal egg counts 15.15 Starting the internal parasite journey – starting with the ewe/lamb(s) unit 16.25 Higher lambing percentages and internal parasite challenges (and opportunities) 18.40 Well fed ewes support good lamb weaning weights, reducing numbers of lambs on farm post-weaning 22.40 Anthelmintic treatments for ewes pre-lambing (or not) 24.10 Ewe nutrition and body condition– building tolerance to internal parasites 28.35 Hatching and development rates of larvae – differs for eggs from ewes and lambs 30.20 Ewe stocking rate combined with other stock classes – optimising ewe nutrition 32.50 Three Pillars of Parasite Management 33.30 First Pillar = well fed, healthy robust breeding stock 33.35 Second Pillar = young stock on clean feed (less worm larvae than average hill country pasture) 34.40 What's the best crop for lambs? 37.45 Feeding lambs the best quality feed that you can – the Third Pillar 38.10 Gross margin analyses on forage crops – understates the value of crops for young stock 39.00 Preparing pasture areas to finish lambs on – integrating cattle with sheep 40.00 100kg calves (dairy replacements, dairy beef) and internal parasites 43.00 Buying in 100kg calves – cautions around risk of parasite resistance 44.20 Holding young stock in yards to empty out after quarantine drenches 46.30 Faecal egg counting in young cattle – usefulness for different ages of cattle 48.40 Trace elements / trace minerals and internal parasites 52.05 Where to go to learn more about internal parasites
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, UK, interviews Professor Loris Lopetuso, Department of Medicine and Ageing Sciences, University of Chieti-Pescara, Italy, on the paper "The first international Rome consensus conference on gut microbiota and faecal microbiota transplantation in inflammatory bowel disease", published in paper copy in Gut in September 2023, and available online: https://gut.bmj.com/content/72/9/1642 Please subscribe to the Gut Podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest podcast every month. If you enjoy our podcast, please consider leaving us a review or a comment on the Gut Podcast iTunes page (https://podcasts.apple.com/gb/podcast/gut-podcast/id330976727).
In this podcast Laura Peachey discusses the faecal microbiome of Exmoor ponies and Pearce Sloan discusses racing performance of juvenile Thoroughbreds with femoropatellar osteochondrosis at auction.
Faecal transplant, also known as faecal microbiota transplantation or FMT, is the transfer of stool from a healthy donor to a patient with a disease. The idea is to restore the balance of bacteria in the gut, which can be disrupted by factors such as antibiotics, diet, or infection but it could potentially help with a range of problems from irritable bowel syndrome to Alzheimer's. Why is faecal transplant used? How does faecal transplant work? How is faecal transplant performed? What are the risks of faecal transplant? In under 3 minutes, we answer your questions! To listen to the last episodes, you can click here : How can I relax my brain while on holiday? What is a ‘lazy girl' job? How can I choose the right mattress for me? A podcast written and realised by Joseph Chance. In partnership with upday UK. Learn more about your ad choices. Visit megaphone.fm/adchoices
On this week's episode of No Holes Barred, Vic shares her close shave with an angry Alsatian, Laura shares her debut foray into doing stand up comedy and the girls discuss whether it's possible to recover from having explosive guts in front of your teenage son. This episode is sponsored by BetterHelp. Give online therapy a try at betterhelp.com/noholes and get on your way to being your best self. Get started today and enjoy 10% off your first month Learn more about your ad choices. Visit megaphone.fm/adchoices
Madeleine Finlay hears from science correspondent Linda Geddes about her experience becoming a faecal transplant donor, how getting a dose of someone else's gut bacteria could treat illnesses like arthritis, diabetes and cancer, and asks whether a pill made from poo is an idea we are ready to swallow. Help support our independent journalism at theguardian.com/sciencepod
Doctors Lisa and Sara talk to Dr Sarah Taylor about the changes being made to how Primary Care Clinicians refer patients for Suspected Lower Gastrointestinal Cancers. These changes are discussed in the context of referring in the Greater Manchester area, but you can view the joint guideline from the Association of Coloproctology of Great Britain and Ireland (ACPGBI) and the British Society of Gastroenterology below. This will change the way we manage patients. To help, we go through some potential cases. Good tips for how to mitigate potential risks with the changes included. We hope you find this useful. You can use these podcasts as part of your CPD - we don't do certificates but they still count :) Useful resources: Faecal immunochemical testing (FIT) in patients with signs or symptoms of suspected colorectal cancer (CRC): a joint guideline from the Association of Coloproctology of Great Britain and Ireland (ACPGBI) and the British Society of Gastroenterology (BSG): https://www.bsg.org.uk/clinical-resource/faecal-immunochemical-testing-fit-in-patients-with-signs-or-symptoms-of-suspected-colorectal-cancer-crc-a-joint-guideline-from-the-acpgbi-and-the-bsg/ GatewayC FIT infographic: http://bit.ly/409mXUy GatewayC Lower GI infographic: http://bit.ly/3XJpIKN Raised Platelets and Cancer Risk: https://gpnotebook.com/en-au/simplepage.cfm?ID=x2019111783915921223 The Current NICE Guidelines last Updated December 2021: https://www.nice.org.uk/guidance/ng12/chapter/Recommendations-organised-by-site-of-cancer#lower-gastrointestinal-tract-cancers ___ We really want to make these episodes relevant and helpful: if you have any questions or want any particular areas covered then contact us on Twitter @PCKBpodcast, or leave a comment on our really quick anonymous survey here: https://pckb.org/feedback ___ This podcast has been made with the support of GP Excellence and Wigan CCG. Given that it is recorded with Greater Manchester clinicians, the information discussed may not be applicable elsewhere and it is important to consult local guidelines before making any treatment decisions. The information presented is the personal opinion of the healthcare professional interviewed and might not be representative to all clinicians. It is based on their interpretation of current best practice and guidelines when the episode was recorded. Guidelines can change; To the best of our knowledge the information in this episode is up to date as of it's release but it is the listeners responsibility to review the information and make sure it is still up to date when they listen. Dr Lisa Adams, Dr Sara MacDermott and their interviewees are not liable for any advice, investigations, course of treatment, diagnosis or any other information, services or products listeners might pursue as a result of listening to this podcast - it is the clinicians responsibility to appraise the information given and review local and national guidelines before making treatment decisions. Reliance on information provided in this podcast is solely at the listeners risk. The podcast is designed to be used by trained healthcare professionals for education only. We do not recommend these for patients or the general public and they are not to be used as a method of diagnosis, opinion, treatment or medical advice for the general public. Do not delay seeking medical advice based on the information contained in this podcast. If you have questions regarding your health or feel you may have a medical condition then promptly seek the opinion of a trained healthcare professional.
Episode 145 feat. Adam, Toddy, Toddy J and Danggers. Come send it with the boys, as we discuss, The return of Covid, Danggers big move, Anus tattoos, WhatsApp girls, Faecal transplants, Blowing shit up, Possums, Mike Tyson gummies, Zelenskyy, Depression, Amber Turd, The rag doll cheater, Rumble Johnson, Abbie Chatfield, War Dogs, and much more... Please forward all complaints to: bigsendbigchat@gmail.com
The Food and Drink Administration in the States has recently recommended the use of faecal transplants to treat various bacterial infections. We spoke to Dr Benjamin Mullish, a researcher at Imperial College London's Department of Metabolism, Digestion and Reproduction, about this promising new technique. Hosted on Acast. See acast.com/privacy for more information.
Gut Immune Body Brain Axis.Dr Gundry:Leaky Gut, gut microbiome and dietRenowned Cardiovascular Surgeon who realised that all he was doing was treating thesymptoms so he studied the underlying causes.The lining of the gut is one cell thickAs bacteria break down the gut that is when ageing startsIbuprofen or roundup disastrous the bacteria populationSkin is a mirror of the lining of the gutJoints do not naturally wear out.Animal model C Elegans as bacteria begin to break down the wall of the gut that is whenageing starts105 year old people have a diverse set of bugs identical to a healthy 30 year old. It is notattacking the wall of the gut.Ecermansia musinophilia. Lives in the mucous layer whose job is to trap lectins plantproteins looking for sugar molecules and to protect the wall of the gut from harmful bacteria.Ecermansia musinophilia eats mucus which in turn makes more mucus.Metformin works by increasing mucous and this change in bacteria makes some peoplehave mild diarrhoea as the bacteria change.If we damage this lining eg ibuprofen or food with roundup destroys the bacteria populationand gut lining.Glyocosade an antibacterial damages Ecermansia Musinophilia even though it does notdirectly affect human cells.Antibiotics in food or direct prescription eg ladies who take low dose for UTI have a higherincidence of heart disease.Heart disease is an autoimmune disease starting in the gut.Cholesterol is an innocent bystander which gets sucked into the inflamed wall of a bloodvessel.Infants with heart transplants have coronary artery disease with pathology identical withtypical coronary artery disease.Lectins which are a foreign protein which can stick to sugar molecules on the surface ofblood vessels are the cause of atherosclerosis and removing lectins reduces those markers.Lectins are one of the plant defence systems. Sticky proteins that look for specific sugarmolecules to stick to which insights an inflammtory response.Joints do not normally wear out. Usually you can find bacterial particles in the joint fluid ofarthritisBecauseLectins broke down the wall of the gut. 65% of the immune system is behind the wall of thegut because the gut is where the outside word gets through. A reason why we store fat inthe gut is to provide energy to the immune system. Similarly fat on the outside ofatherosclerotcic blood vessles correlates with the severity of inflammation.Fat is not the cause . It is there because of the inflammation and the inflammation is theredue to the leaky gut.The immune system responds to antigens on bacteria of viruses. Lectins have antigens withcross reactivity with other proteins in the body. Eg thyroid.Nightshade vegetables or peanutsLectins disrupt the microbiome and break up the lining of the gut allowing entry by lectinsand by bacteria or bacterial particles.Hence if you inject a bacterial lipopolysaccharide into a person you can induce septic shock.Alzheimers Parkinsons is neuroinflammation.Most amyloid is produced by bacteria in the gut. Therefore 40 billion dollars invested inantiamyloid drugs has been a waste because amyloid is produced by the amyloid producingbacteria inthe gut fet by western diet. Then the amyloid has to get through the wall of the gut.Once they get through the gut wall and goto the brain it will produce more amyloid.Cholesterol and amyloid coexist in dementia in those with the apoE gene.The apo E gene codes for a carrier molecule because it is less efficient at transportingcholesterol. It cannot get out of the cell after it has been attracted by inflammation.Faecal microbial transplant:1970s broad spectrum antibiotics came out which made it much quicker to treat infectionsbut it also wiped out the gut bacteria. Normally 10000 species of bacteria.Pseudomembranous colitis was caused by Clostridium Difficile over growing. Initial studydone from the faeces of medical students.Faecal enemas treated the pseudomembranous colitis.Meat with animals treated by antibiotics can also cause problems.60% of faeces is bacteriaOral microbiome and cloud of bacteria around us –Holobiome . This defines our personalspace.Kissing is a human and ape characteristic. Exchanging oral microbiome. Bacteria decidewhether the other person's bacteria are compatible with them.Women have a gut feeling because they are more capable of listening to their microbiome. We inherit our microbiome from our mother. All of the mitochondria are involved with bacteriainherited from our mother. Bacteria communicate to their ‘sisters 'ie the body's mitochondria.Autism: kids have a different microbiome than ‘normal'The placental microbiome is important in educating the foetal immune system.Oral faecal transplants for 6 weeks in autistic kids. Almost immediately 50% autismsymptoms reduced.Ecermansia like tubers, mushrooms, -study in Asia find 90% reduction in Alzheimers withtwo cups of mushrooms a week.Inulin containing compounds eg chicory, radicchio, jerusalem artichoke.Exercise women who exercise routinely from midlife have a 90% reduction in Alzheimers. Inthose who get AD it happens 11 years later. Housework can be important part of exercise.Meditation and yoga also changes the gut microbiome.Lymph system in the brain in deep sleep -early in the sleep cycle-shrinks by 20% and thesebad proteins are squeezed out. You need a 3-4 hour window between sleep and dinnerbecause blood flow diverts to the gut.Olive oil /walnuts / mediterranean low fat diet: first two groups improved memory after 5years. 3rd group lost memoryThose with CVD had a 30% reduction in events, the low fat group continued CVS events.Polyphenos in olive oil grow proteinsTMAO is made by gut bacteria primarily from animal protein especially choline eg egg yolkand carnitine . TMAO damages blood vessels. Polyphenols in certain olive oil and red winebalsamic vinegar that paralyse enzyme systems in the bacteria so they do not make TMAO.However the logical error here is that eggs which are high in choline are not associated withincreased morbidity.Vitamin D at least 5000 units a day . Almost all cancer patietns and autoimmune pateitnshave low vitamin D. HIgher your VItamin D the longer your telomere. Stem cells in the gutare simulated by vitamin D.VItamin CLectins are present in most plant foods but especially high in:legumes, such as beans, lentils, peas, soybeans, and peanutsnightshade vegetables, such as tomatoes and eggplantdairy products, including milkgrains, such as barley, quinoa, and riceThe Roll of Inflammation in Depression and FatigueFrontiers In Immunology:CH Lee 2019:Immune system link to depression first noticed with immunotherapy eg INFa (which activates an inflammatory antiviral response) for Hepatitis C : associated with raised proinflammatory cytokines and depression and fatigue.20% of patients treated with INFa developed depression which resolved on discontinuationbut also increased the risk of depression in future.Also people with higher IL6 aged 9 were more likely to have depression aged 18 in a dosedependent manner.Innate immune system seems to be lower in depression eg NK cells and also less antiinflammatory regulatory T cells whereas inflammatory monocytes are activated.There is commonality in immune activation from autoimmune disorder such as multiplesclerosis or immune reactions in sepsis.Antidepressants reduce inflammation while a higher baseline level of inflammation predicts apoorer treatment response.People with depression have been shown to have higher inflammatory markers which canbe used to predict treatment efficacy and future recurrences of depression.Elevated inflammatory markets eg TNFa after an MI disrupt the blood brain barrier causingdepression.Inflammatory changes in the brain with raised TNFa in the hippocampus and striatumprecede development of depressive symptoms.Neurogenesis is inhibited by the kynurenine pathway which is rescued by both inhibitors ofthis pathway and traditional antidepressants.TNFa also increases glutamate release causing exocytotic damage to surroundingsneurones.Conditions associated with chronic immune activation such as asthma, atopy, diabetes mMS, RhA, SLE are all associated with raised levels of depression eg 36% of asthma havedepression who also had higher TNFa than those who were not depressed. 75% in RhAMS up to 50% risk of depression.Acute inflammation with sepsis also causes depression and raises the risk of depression infuture which in animal models can be reduced by using steroid during the acute sepsis.Antidepressants reduce inflammatory markers perhaps SNRI more effective than SSRI andalso ECT adds in return to normal of NK activity.Directly reducing the immune response eg anti TNF a or Caspase Inhibitors have beenshown to reduce depression. Rituximab which is an antibody that targets and depletes Bcells in the treatment of RhA also reduces depression.Aspirin can reduce depression but can also reduce the effect of an SSRI.
Dr Philip Smith, Digital and Education Editor of Gut and Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK, interviews Professor Peer Bork, Director of the Heidelberg site of the European Molecular Biology Laboratory Heidelberg, Baden, Germany on the paper 'A faecal microbiota signature with high specificity for pancreatic cancer' published in paper copy in Gut in July 2022, and available online: https://gut.bmj.com/content/71/7/1359 Please subscribe to the Gut Podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest podcast every month. If you enjoy our podcast, please consider leaving us a review or a comment on the Gut Podcast iTunes page (https://podcasts.apple.com/gb/podcast/gut-podcast/id330976727).
This week's podcast is supported by our friends over at Nuzest. You can get 20% off their amazing vegan protein by visiting nuzest.us/pbn20! Welcome back to another episode of the Plant Based News podcast. Today we sit down today with leading gastroenterologist, nutritionist, and author Dr. WIll Bulsiewicz. Dr. WIll Bulsiewicz, also known as Dr. B and The Gut Health MD, is a graduate of Georgetown University School of Medicine. He trained in internal medicine at Northwestern Memorial Hospital and in gastroenterology at The University of North Carolina Hospitals. He is board-certified in internal medicine and gastroenterology and an expert in digestive diseases. He is a New York Times, USA Today, and Publishers Weekly bestselling author and his latest cookbook “The Fiber Fueled Cookbook” extends his previous work by delivering “deeply flavorful, satisfying plant-based recipes” that target food intolerances. I am thrilled to welcome Dr WIll Bulsiewicz to this episode of the PBN podcast, where we'll dig deeper into what makes for a good diet and a healthy gut, how to combat food intolerances as well as his own journey as a physician and an author. 00:00:00 Nuzest Sponsor Promo 00:03:20 An introduction to Dr Will Bulsiewicz 00:06:10 The beginning of Dr B's plant-based journey 00:14:10 YouTuber Rachel tries out the Fibre Fuelled food plan 00:16:45 Plant Based News' Robbie Lockie's food intolerance 00:26:10 What is happening in the body when people experience pain from food intolerance? 00:36:30 What should we do to protect our immune system during the pandemic? 00:47:00 The importance of a covid-19 vaccine and a healthy diet 01:04:20 Faecal transplants 01:09:30 The connection between our brain and our gut 01:18:40 Shared microbes: the importance of food in relationships Find out more about Dr B here - https://theplantfedgut.com/ Find the transcript here - https://share.descript.com/view/YrluK0mLnaN The PBN Podcast is hosted and produced by Robbie Lockie, Edited by Phil Marriott.
Ja, dat klinkt nogal vies. Maar dat is precies waar onderzoekers naar gekeken hebben: kan het transplanteren van poepmicroben veroudering tegengaan? Het transplanteren van deze microben van de ene persoon naar de andere heeft al langer de aandacht van onderzoekers. Zo is al gekeken of op die manier problemen met darmflora opgelost kunnen worden. Dan worden de goedwerkende microben van een donor, geplaatst bij iemand waarbij het darm-microbioom verstoord is. Nu hebben onderzoekers bij muizen gekeken: wat gebeurt er als we de microben van jong naar oud transplanteren? Ze zagen dat door dit te doen, veroudering in de darm, ogen en hersenen deels teruggedraaid kon worden. Draaiden ze het experiment om en plaatsten ze microben van oude muizen in jonge muizen, dan kregen deze muizen allemaal vervelende klachten. Het team van onderzoekers wil nu nog kijken hoe de microben nou precies deze veranderingen ingang zetten en hoe lang het effect aanhoudt. Lees meer: Faecal transplants reverse hallmarks of ageing. See omnystudio.com/listener for privacy information.
Dive into some recent news, and things going on with the ICEBAR podcast. ICEBAR stickers are selling for only 3$ make sure to buy a sticker to support one of the best podcasts.
Australia is lucky to have free healthcare services—but there can be big gaps in who receives it; reports on two people with bipolar disorder finding benefit from a faecal microbiota transplant; and how stomas help the intestine heal.
Recently published, independent, and peer-reviewed Australian case studies have reported on two people with bipolar disorder finding that their symptoms eased, or even disappeared, after they had a faecal microbiota transplant. So what do your poo and your mood have in common?
Raana attempts to hide in the Dino Dens but Silaqui is convinced there's another way to find out if Bone Cruncher is being given performance enhancing drugs. Taban and Percival consider a proposition by Kweothe. Please subscribe, download and review us! https://linktr.ee/TotTTBpodcast With great thanks and love, Trolls of the Two Tonne Bridges uses music and sound from the following artists: 3 Ghosts I 8 Ghosts I by Nine Inch Nails Creative Commons Attribution Non-Commercial Share Alike license License: http://creativecommons.org/licenses/by-nc-sa/3.0/us/ Tempting Secrets by Kevin MacLeod Link: https://incompetech.filmmusic.io/song/5005-tempting-secrets License: http://creativecommons.org/licenses/by/4.0/ Vanishing by Kevin MacLeod Link: https://incompetech.filmmusic.io/song/4578-vanishing License: http://creativecommons.org/licenses/by/4.0/ Bathhouse by Michael Ghelfi YouTube: https://www.youtube.com/user/MichaelGhelfi Patreon: http://www.patreon.com/MichaelGhelfi Various by Tabletop Audio Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License License: https://creativecommons.org/licenses/by-nc-nd/4.0/ (All audio may have been edited for length or context)