Podcasts about statins

Statin Myopathy   Guest: Stephen Kopecky, M.D. Host: Sharonne Hayes, M.D.   Statins are very helpful to lower LDL cholesterol and subsequently lower cardiovascular risk.  Studies of statins have excluded subjects that are statin intolerant which is usually due to muscle symptoms such as aches, called myalgias, muscle cramps, or weakness.  One of the most significant predictors of statin intolerance is the dose -the higher the dose, the more likely to develop intolerance.  Accepted in recommended ways to minimize intolerance is to use generic combination therapy with a lower dose statin and a cholesterol absorption inhibiting agent such as ezetimibe.  Newer agents such as PCS K 9 inhibitors and inclisiran, both given subQ, and bempedoic acid may reduce statin muscle symptoms.   Topics Discussed: Is any statin more or less likely to cause statin associated muscle symptoms? Are there any protective medications that can minimize statin myalgias? What newer non-statin agents have been shown to reduce risk of myalgias? How is treating high cholesterol levels becoming more like treating blood pressure?     Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices. LinkedIn: Mayo Clinic Cardiovascular Services Cardiovascular Education App: The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today! No CME credit offered for this episode.   Podcast episode transcript found here.

Alternatives to surgery for venous insufficiency; AI “hallucinates” a never-before-seen brain region in crucial test; Vegetarian complains she is prone to falling; Could tinnitus be triggered by electromagnetic fields from lighting, devices? Cannabis derivatives improve sleep where drugs fail; A novel way of treating chronic nasal infections—with snot transplants! Mitochondrial dysfunction found to be the key to heart, brain problems.

Most people think heart disease is caused by cholesterol—but the real problem is hidden in the foods you eat every day. In this episode,  Ben Azadi reveals seven artery-healing superfoods that naturally raise HDL, lower triglycerides, and unclog your arteries—without statins or surgery.  You'll also learn the “healthy” food combos that are secretly destroying your heart, and the simple daily habits that boost nitric oxide, reduce inflammation, and protect your cardiovascular system for life. Resources:

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This is a fascinating podcast episode from Dr. Lipid himself on desmosterol.  What is it?  How do we measure it?  Why should we care? Pharmacists are well-positioned to guide patients in understanding the role of desmosterol, how medications may influence its levels, the options for measuring it, and the steps to take if levels are too high or too low. Dr. Thomas Dayspring: linkedin.com/in/thomas-dayspring-md-facp-fnla-3aaa876 or @DrLipid on X  Tamara Ruggles, PharmD: linkedin.com/in/tamara-ruggles-491882251 Resource on lipids recommended by Dr. Dayspring: https://familyheart.org/ Wages PA, Kim HH, Korade Z, Porter NA. Identification and characterization of prescription drugs that change levels of 7-dehydrocholesterol and desmosterol. J Lipid Res. 2018 Oct;59(10):1916-1926. doi: 10.1194/jlr.M086991. Epub 2018 Aug 7. PMID: 30087204; PMCID: PMC6168312.  Available at:  https://pubmed.ncbi.nlm.nih.gov/30087204/  The Geriatric Pharmacy Focus podcast is for general informational purposes only and does not constitute the practice of medicine, nursing or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast or materials linked from this podcast is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professionals for any such conditions.

Ready for your personalized care plan?: Call us Now: 859-721-1414 or visit https://prevmedhealth.com/ Get My 7- Step Heart Attack Prevention Protocol free ebook here: https://45413573.hs-sites.com/ebook

Potato intake and diabetes risk.How much daily leucine is required to regain muscle?

I have high LDL cholesterol and a '0' calcium score.  Why does my doctor insist I take a statin?How much vitamin D should I take?  Which product do you recommend?Some doctors assert omega-3s are proinflammatory.  What say you?Study: Magnesium intake may be beneficial in preventing pancreatic cancerDo you have any products to regrow hair?I have a calcium score, but prefer to avoid Lipitor.

In this pod Consultant Rheumatologist, Dr Judith Jade, chats with Dr Fergus To, Rheumatologist from British Columbia, about the case of a woman who presented with subacute muscle weakness. They discuss how to approach these types of  cases systemically with some handy tips along the way. Listen in and see if you can work out what the diagnosis is!References:1. Blazing M, et al. Effect of statin therapy on muscle symptoms: an individual participant data meta-analysis of large-scale, randomised, double-blind trials. Lancet. 2022;400(10355):832–452. Kim EJ, Wierzbicki AS. Investigating raised creatine kinase. BMJ. 2021;373:1–5.3. Sharf K, Do T, Ghetie D, Choi D, Chahin N. Benefits of Early vs Late Initiation of IVIG in the Treatment of Anti‐HMGCR Immune‐Mediated Necrotizing Myopathy. Arthritis Care Res (Hoboken) 2024;76:1584–92. https://doi.org/10.1002/acr.25406.4. Allenbach et al, 224th ENMC International Workshop, Neuromuscular Disorders, Volume 28, Issue 1, 87 - 99Thanks for listening to Talking Rheumatology! Join the conversation on X using #TalkingRheum or tweet us @RheumatologyUK.BSR is the UK's leading specialist medical society for rheumatology and MSK health professionals. To discover how we can support you in delivering the best care for your patients, visit our website.

God's Debris: The Complete Works, Amazon https://tinyurl.com/GodsDebrisCompleteWorksFind my "extra" content on Locals: https://ScottAdams.Locals.comContent:Politics, Emotional Politics, Dumb Portugal President, Stonehenge Cows, President Trump's Holiday Weekend, Politically Assigned Opinions, Emergency Powers Tariffs, Statins, Maxine Waters, Democrat Imaginary Concerns, Airborne Power Generator, DNC Land Acknowledgement, James Carville's DNC Advice, Robot Surgeons, DEI Surgeons, Putin Xi Kim Summit, DC Crime Reduction, Federal Cost-Reduction Cuts, Federal Funds Theft, Israel Hamas War Deaths, Gaza Health Ministry, Scott Adams~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~If you would like to enjoy this same content plus bonus content from Scott Adams, including micro-lessons on lots of useful topics to build your talent stack, please see scottadams.locals.com for full access to that secret treasure.

Send us a textWide release date: August 25, 2025Episode Summary: Dr. Uffe Ravnskov talks about his decades-long career challenging the idea that high cholesterol causes heart disease, discussing LDL's protective role in the immune system by binding to bacteria, the harms and biases in statin research influenced by pharmaceutical companies, evidence that high cholesterol benefits the elderly and reduces infection/cancer risks, and how mental stress or infections elevate cholesterol as a response rather than a cause.About the guest: Uffe Ravnskov, MD, PhD is a physician and independent researcher who earned his MD from the University of Copenhagen in 1961 and a PhD in nephrology. He has worked in various clinics in Sweden since the 1960s, focusing his research on challenging the cholesterol hypothesis in heart disease. Now 91, he has published over 200 papers, authored books like "The Cholesterol Myths.”Discussion Points:LDL cholesterol helps the immune system by sticking to bacteria, clumping them for removal; low LDL increases infection risk.Animal studies show injecting LDL protects against lethal infections, while historical data links severe infections to worse atherosclerosis.Elderly people with high cholesterol live longer; low cholesterol raises mortality risk more than high levels.Familial hypercholesterolemia (FH) doesn't cause early death via cholesterol alone—co-inherited coagulation factors are the issue, and FH patients often have lower infection rates.Statins lower LDL but increase infection risk, cause muscle weakness/brain issues (often blamed on aging), and show no clear benefit in unbiased meta-analyses.Research biases include cherry-picking studies, exaggerating benefits via relative (not absolute) risk, and pharma funding suppressing critical views.Mental stress can raise cholesterol by 10-50% in 30 minutes, often misread as a heart disease cause rather than an effect.Saturated fat and high cholesterol aren't proven harmful; Ancel Keys' claims ignored contradictory evidence.Stopping statins often reverses side effects quickly, improving quality of life.Related episode:M&M 244: Seed Oils & Heart Disease: Oxidized LDL, Cholesterol, Fat & Cardiology | Tucker GoodrichReference Paper:LDL-C does not cause cardiovascular disease: a comprehensive review of the current literature*Not medical advice.Support the showAffiliates: Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off SiPhox Health—Affordable at-home blood testing. Key health markers, visualized & explained. Code TRIKOMES for a 20% discount. For all the ways you can support my efforts

Report shows rapid declines in health of children and adolescents since 2007; N-acetylcysteine (NAC) for Parkinson's; Statins increase likelihood of hearing loss, tinnitus; Lithium orotate for Alzheimer's; Is tinnitus reversible? Novel implantable electrical vagus nerve stimulator approved for treatment of rheumatoid arthritis.

Josh Wageman is a board-certified Clinical Lipid Specialist dedicated to transforming the way we understand and treat heart disease. With a deep expertise in cholesterol, metabolic health, and cardiovascular risk, he helps patients cut through the noise and take control of their health using evidence-based, personalized strategies. Known for translating complex science into actionable steps, Josh is passionate about prevention and proving that heart disease doesn't have to be inevitable. In this episode, Dr. Brian and Josh talk about… (00:00) Intro (00:32) Josh's interesting and varied career path (04:31) Understanding cardiovascular disease in a nutshell (8:15) Understanding lipoproteins (10:10) Why lipids are controversial and what we can all agree on (12:28) LDL and HDL particles (19:35) Endurance athletes and coronary calcium (29:54) Atherosclerosis, carnivore, and gut dysbiosis (39:46) Advanced lipid panels (40:29) Statins and LDL (44:13) Pros and cons of statins (49:54) Supplements that may be helpful for cardiovascular health (52:44) Rapping and singing about lipids and heart health (55:09) Science and faith; physical health and spiritual health (01:02:25) Outro For more information, please see the links below. Thank you for listening! Links: Please consider supporting us on Patreon: https://www.lowcarbmd.com/ Josh Wageman: IG: https://www.instagram.com/wagemanjosh/ Book: https://www.amazon.com/Security-System-Lipid-Neighborhood-Complicating/dp/B0DTJ1HJ4Y Dr. Brian Lenzkes:  Website: https://arizonametabolichealth.com/ Twitter: https://twitter.com/BrianLenzkes?ref_src=twsrc^google|twcamp^serp|twgr^author Dr. Tro Kalayjian:  Website: https://www.doctortro.com/ Twitter: https://twitter.com/DoctorTro Instagram: https://www.instagram.com/doctortro/ Toward Health App Join a growing community of individuals who are improving their metabolic health; together.  Get started at your own pace with a self-guided curriculum developed by Dr. Tro and his care team, community chat, weekly meetings, courses, challenges, message boards and more.  Apple: https://apps.apple.com/us/app/doctor-tro/id1588693888  Google: https://play.google.com/store/apps/details?id=uk.co.disciplemedia.doctortro&hl=en_US&gl=US Learn more: https://doctortro.com/community/ 

Thomas Sowell, one of the most incisive thinkers of our time, warned repeatedly about the dangers of intellectuals detached from real-world consequences. Though he rarely addressed medicine directly, his insights are strikingly applicable to today's healthcare crisis-a system dominated by academic elites, rigid guidelines, and centralized authority, while practical, patient-centered wisdom is sidelined.Nowhere is this intellectual overreach more harmful than in modern medicine. Medical Contributor Dr. Jeff Crippen discusses: Statins and Longevity

This episode is brought to you by the ⁠⁠⁠Primal Tallow Balms⁠⁠⁠.Dr Kendrick emphasizes the lack of scientific evidence linking high cholesterol to heart disease and argues that a higher fat diet can have positive effects on health. The discussion also covers the complexities of LDL cholesterol, the importance of understanding various health markers, and the potential effects of adopting a high-fat diet. In this conversation, Dr. Malcolm Kendrick discusses the complexities of heart health, focusing on the role of blood clots, the impact of diet on cardiovascular health, and the misconceptions surrounding cholesterol and statins. He emphasizes the importance of understanding the glycocalyx and its protective role in blood vessels, the benefits of a high-fat diet, and the potential for plaque regression. Kendrick also critiques the use of statins, arguing that their benefits are often overstated and come with significant side effects. Takeaways* Cholesterol is often misunderstood in relation to heart disease.* Changing medical opinions is challenging due to entrenched beliefs.* High-fat diets can have positive health impacts.* LDL cholesterol is often mischaracterized as harmful.* The relationship between dietary fat and heart health is complex.* Markers like triglycerides and HDL are important for assessing heart health.* Insulin resistance is a key factor in heart disease risk.* The disease process in arteries can take decades to develop.* LDL levels can be influenced by carbohydrate intake, not just fat.* Understanding the nuances of cholesterol can empower patients. Blood clots form on artery walls and can lead to heart disease.* A high-fat diet can improve blood sugar levels and overall health.* The glycocalyx is crucial for protecting blood vessels from damage.* Diabetes damages the glycocalyx, increasing heart disease risk.* A 30-day high-fat diet can lead to significant health improvements.* Stopping the progression of plaque is more important than regression.* Statins may increase nitric oxide but have many adverse effects.* The average increase in life expectancy from statins is minimal.* Challenging your doctor about statin use can be beneficial.* Understanding the true causes of heart disease is essential for prevention.

You've cut the calories. You've tried the workouts. You've pushed through exhaustion and cravings—and still, the weight won't budge.It's not your fault.It's not your discipline.And it's not just age.⚠️ The truth?Most women over 40 are stuck in fat-storing mode—not because they're doing it wrong, but because their hormones, thyroid, blood sugar, and stress signals are screaming for support. And your lab work is the roadmap you've been missing.EVEN if your doctor says it's “normal” we look for optimalBecause doctors can't prescribe you anything until it is out of rangeAnd at that point we are trying to get out of a pretty deep hole.We want to optimize your health, lab levels and take control before things get worse!In this free, value-packed webinar, I'll show you how to:

In this episode, I sit down with Dr. Rupy Aujla, an NHS GP and the founder of The Doctor's Kitchen, an app that includes doctor-approved recipes to cook at home. In this conversation, we dive into why cardiovascular disease remains the #1 killer worldwide, the connection between cholesterol and heart health, how fiber acts as a “magical nutrient” for the body, how to introduce it into your daily meals, and the role of lifestyle choices in preventing illness and supporting long-term brain and heart health. *** About Dr. Rupy Aujla: After suffering a significant heart condition, he dove deep into the science of nutritional medicine and was able to reverse his condition through food and lifestyle. In 2015, he launched The Doctor's Kitchen as a way to teach people how to cook their way to better health and to showcase the medicinal effects of eating well. The incredible “Doctor's Kitchen” cooking app has over 1000 delicious, science-backed recipes and 20 brand new ones added each month. There's also a handy meal planner that will personalise recipes based on your preferences. It actually suggested a delicious looking salmon poached in harissa coconut sauce, and  olive and date braised chicken, which suit my personal dietary needs and all sound great. You can download and use the app completely for free using this link. *** Subscribe to The Neuro Experience for more conversations at the intersection of brain science and performance. I'm committed to bringing you evidence-based insights that you can apply to your own health journey. *** A huge thank you to my sponsors for supporting this episode. Check them out and enjoy exclusive discounts: David's Protein: Buy four cartons and get your fifth one completely free | Head to https://davidprotein.com/pages/neuro Ketone IQ: Go to https://ketone.com/NEURO for 30% OFF your subscription order + receive a free gift with your second shipment. FIGS: You can get 15% off your first order at https://wearfigs.com with the code FIGSRX. Caraway: https://caraway.com/neuro for an additional 10% off your purchase MUDWTR: The coffee alternative. If you're ready to ditch the crash and sip smarter, go to https://mudwtr.com and use code NEURO to get 43% off + free shipping. *** I'm Louisa Nicola — clinical neuroscientist — Alzheimer's prevention specialist — founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain — reducing Alzheimer's risk — and staying mentally sharp for life, you're in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ *** Topics: 00:02:43: Lipid panels & overlooked markers 00:05:21: Atherosclerosis explained 00:08:13: Misleading “normal” cholesterol panels 00:10:48: Why heart disease remains #1 killer & prevention timeline 00:12:51: Cholesterol & Alzheimer's; LDL targets for brain health 00:15:12: Cholesterol causality, very low LDL safety 00:19:23: Statins & pharmacological interventions 00:26:02: Ultra-processed foods & saturated fats 00:29:26: Fiber's role in lowering LDL 00:32:05: How fiber binds bile acids & removes cholesterol 00:33:29: Gut microbiome & short-chain fatty acids from fiber 00:35:05: Lowering ApoB, LDL by eating plant-rich foods, portfolio diet 00:37:15: Oats & heart health 00:41:51: Pesticides in fruits and vegetables 00:45:37: Eggs and cholesterol 00:48:18: Soy 00:53:55: Balanced eating 00:57:40: Stress, sleep & cardiovascular disease 00:59:55: Memorable patient stories, family member with stent 01:04:04: How to reduce risk of heart attack or stroke with diet Learn more about your ad choices. Visit megaphone.fm/adchoices

In this episode, Tim and May ask a simple question: What if avoiding the sun is actually worse for your health?They unpack a Swedish study that links low sun exposure to the same death risk as smoking, challenge dermatology dogma, and remind us why we're solar-powered beings. It's honest, irreverent, and a call to live fully—outside, under the sun.GET SOCIAL WITH US!

Dr. Robert Baron reviews best practices in lipid management for preventing cardiovascular disease, with a focus on statin use. He outlines the strong evidence for statins in reducing heart attack and stroke risk by 25–33%, particularly in patients with clinical atherosclerotic disease, diabetes, or high LDL. He explains why shared decision-making is key in primary prevention, where guidelines vary and risk thresholds are debated. Baron discusses the shift to the newer PREVENT risk calculator, which offers improved accuracy and removes race as a factor. He also explains when additional lipid-lowering medications may be appropriate and clarifies the impact of risk-enhancing factors like family history, coronary artery calcium, and LP(a). [Health and Medicine] [Show ID: 40755]

Dr. Robert Baron reviews best practices in lipid management for preventing cardiovascular disease, with a focus on statin use. He outlines the strong evidence for statins in reducing heart attack and stroke risk by 25–33%, particularly in patients with clinical atherosclerotic disease, diabetes, or high LDL. He explains why shared decision-making is key in primary prevention, where guidelines vary and risk thresholds are debated. Baron discusses the shift to the newer PREVENT risk calculator, which offers improved accuracy and removes race as a factor. He also explains when additional lipid-lowering medications may be appropriate and clarifies the impact of risk-enhancing factors like family history, coronary artery calcium, and LP(a). [Health and Medicine] [Show ID: 40755]

Dr. Robert Baron reviews best practices in lipid management for preventing cardiovascular disease, with a focus on statin use. He outlines the strong evidence for statins in reducing heart attack and stroke risk by 25–33%, particularly in patients with clinical atherosclerotic disease, diabetes, or high LDL. He explains why shared decision-making is key in primary prevention, where guidelines vary and risk thresholds are debated. Baron discusses the shift to the newer PREVENT risk calculator, which offers improved accuracy and removes race as a factor. He also explains when additional lipid-lowering medications may be appropriate and clarifies the impact of risk-enhancing factors like family history, coronary artery calcium, and LP(a). [Health and Medicine] [Show ID: 40755]

Dr. Robert Baron reviews best practices in lipid management for preventing cardiovascular disease, with a focus on statin use. He outlines the strong evidence for statins in reducing heart attack and stroke risk by 25–33%, particularly in patients with clinical atherosclerotic disease, diabetes, or high LDL. He explains why shared decision-making is key in primary prevention, where guidelines vary and risk thresholds are debated. Baron discusses the shift to the newer PREVENT risk calculator, which offers improved accuracy and removes race as a factor. He also explains when additional lipid-lowering medications may be appropriate and clarifies the impact of risk-enhancing factors like family history, coronary artery calcium, and LP(a). [Health and Medicine] [Show ID: 40755]

To submit a question for us to answer on the podcast, go to brainjo.academy/question. To subscribe to The Better Brain Fitness newsletter and get our Guide and Checklist to essential blood tests and nutrients, go to: betterbrain.fitness. To learn more about how you can boost brain fitness with neuroscience-based musical instruction, head to brainjo.academy.  Intro and Outro music composed and produced by Julienne Ellen.   

As a PhD nutritionist and registered dietitian, I'm breaking down 7 powerful foods that naturally lower bad cholesterol—no statins required. Learn how these foods reduce inflammation, improve HDL, and support heart health, all backed by science and real client results.GET A CUSTOMIZED WEIGHT LOSS PLAN: Have a free 1-on-1 call with our Expert Nutritionists 

Natural alternatives for Trump's chronic leg swelling problems; How certain blood and urine tests can help predict osteoporosis; Dark chocolate enhances cognitive function—with lasting effects; caffeinated black coffee reduces risk of death by 14%; NY Times misses the boat again on supplements for immunity; Man dies after being pulled into MRI machine.

0:00- Intro0:10- N=1 experimentation5:00- People hating on tried and true exercises15:00- Skill levels of different exercise modalities  27:00- Making excuses30:30- Vegan diet and dietary effects on health and performance58:00- Statins 1:06:00- Where to find Alex

Joined by Heidi (Unfiltered Rise) to discuss the purpose of cholesterol, the norms, and the introduction of medications to "treat".  We delve deeply into the history of studies, funding, drug creation, side effects, benefits versus risks, and more. #cholesterol #triglycerides #drugs #statins #sideeffects #damage #studies #penicillin #fungus   Follow Heidi at www.unfilteredrisepodcast.com IG @unfilteredrise_podcast  X @UnfilteredRise On Patreon and Spotify

Why do we screen for cancer but not the leading cause of death — heart disease? Today, we explore innovative strategies for early detection, prevention, and effective intervention in cardiovascular health.Join hosts Dr. Emmie Brown, ND, and Melissa Gentile, INHC, as they welcome Dr. Joel Kahn, a renowned cardiologist and advocate for plant-based nutrition and holistic approaches to heart health. Dr. Kahn delves into why heart disease has stubbornly remained the leading cause of death despite medical advancements, highlighting the need for a paradigm shift in prevention and early detection.Dr. Kahn critiques the current lack of attention paid to proactive cardiovascular screening, noting the puzzling discrepancy between routine cancer screenings and the absence of widespread use of tools like coronary artery calcium (CAC) CT scans for asymptomatic adults. He champions a personalized, comprehensive approach, moving beyond basic lipid panels and into genetic testing, advanced inflammatory markers, and detailed imaging.They also discuss dietary strategies, including debates on the role of protein and seed oils in heart risk, the importance of the endothelial glycocalyx, and recommendations for clinicians to assess and communicate vascular risk. Dr. Kahn challenges both traditional and trendy wellness beliefs, promoting evidence-based, personalized strategies in integrative cardiology.Key Takeaways from Today's Episode:

BUFFALO, NY – July 22, 2025 – A new #research paper was #published in Volume 16 of Oncotarget on July 21, 2025, titled “Statins exhibit anti-tumor potential by modulating Wnt/β-catenin signaling in colorectal cancer.” In this work, led by first author Sneha Tripathi from the Indian Institute of Science Education and Research and corresponding author Sanjeev Galande from the Center of Excellence in Epigenetics at Shiv Nadar University, researchers discovered that statins, widely used to lower cholesterol, may also suppress colorectal cancer growth. This finding highlights a potential new role for these common drugs in cancer prevention and therapy. Colorectal cancer is one of the leading causes of cancer-related deaths worldwide, and new strategies are urgently needed to improve treatment results. Statins, originally developed to lower cholesterol levels, have gained attention for their possible anti-cancer properties. The study investigated how statins affect the Wnt/β-catenin signaling pathway, a critical driver in colorectal cancer development and progression. The researchers discovered that statins disrupt the Wnt/β-catenin signaling pathway, leading to lower levels of tumor-promoting proteins and to cancer-suppressing cellular behaviors. Experiments in both colorectal cell cultures and mouse models confirmed that statins reduced tumor growth without causing noticeable side effects. This study further revealed that statins downregulate SATB1, a protein linked to aggressive tumor behavior, while increasing SATB2, a protein with tumor-suppressing effects. These changes made the cancer cells less able to grow and spread. “This reciprocal regulation shifts cellular phenotypes between epithelial and mesenchymal states in 3D spheroid models.” Overall, the findings suggest that statins could be repurposed to complement existing colorectal cancer treatments or even be used in preventive strategies for high-risk individuals. By targeting the molecular machinery that drives colorectal tumor development, statins offer a promising, accessible, and well-understood option for further research in cancer therapy. This research opens the door to larger clinical studies to explore how best to integrate statins into cancer care. If successful, this approach could provide a cost-effective strategy for reducing the global burden of colorectal cancer, which remains a significant health challenge. DOI - https://doi.org/10.18632/oncotarget.28755 Correspondence to - Sanjeev Galande - sanjeev.galande@snu.edu.in Video short - https://www.youtube.com/watch?v=A95ICULaH3Y Sign up for free Altmetric alerts about this article - https://oncotarget.altmetric.com/details/email_updates?id=10.18632%2Foncotarget.28755 Subscribe for free publication alerts from Oncotarget - https://www.oncotarget.com/subscribe/ Keywords - cancer, colorectal cancer, statins, SATB1, Wnt/β-catenin signaling, tumor-suppressive phenotype To learn more about Oncotarget, please visit https://www.oncotarget.com and connect with us: Facebook - https://www.facebook.com/Oncotarget/ X - https://twitter.com/oncotarget Instagram - https://www.instagram.com/oncotargetjrnl/ YouTube - https://www.youtube.com/@OncotargetJournal LinkedIn - https://www.linkedin.com/company/oncotarget Pinterest - https://www.pinterest.com/oncotarget/ Reddit - https://www.reddit.com/user/Oncotarget/ Spotify - https://open.spotify.com/show/0gRwT6BqYWJzxzmjPJwtVh MEDIA@IMPACTJOURNALS.COM

Show notes: (0:00) Intro (1:03) Dr. Hussey's health journey and heart attack at 34 (3:08) What causes heart disease (7:59) Why cholesterol tests might be misleading (13:57) How structured water protects your arteries (22:12) Statins are not always the correct solution (29:14) The truth about heart scans vs. cholesterol panels (32:26) Why daily sunlight might be key to healing (40:49) Foods and habits that damage your heart (44:29) How to protect your circadian rhythm in a modern world (48:09) Dr. Hussey's new book and where to follow his work (51:19) Outro   Who is Dr. Stephen Hussey?   Dr. Stephen Hussey MS, DC is a Chiropractor and Functional Medicine practitioner.   He attained both his Doctorate of Chiropractic and Masters in Human Nutrition and Functional Medicine from the University of Western States in Portland, OR. He is a health coach, speaker, and the author of three books on health; The Health Evolution: Why Understanding Evolution is the Key to Vibrant Health, Understanding The Heart: Surprising Insights Into The Evolutionary Origins Of Heart Disease – And Why It Matters, and Pain Sense: Revolutionary Insights into Human Physiology and How it Helps Us Understand and Eliminate Chronic Pain. Dr. Hussey guides clients from around the world back to health by using the latest research and health attaining strategies. In his down time, he likes to be outdoors, play sports, read, write, and travel.   Connect with Dr. Hussey: Website: https://resourceyourhealth.com/ IG: https://www.instagram.com/drstephenhussey/   Grab a copy: https://resourceyourhealth.com/shop/   Links and Resources: Peak Performance Life Peak Performance on Facebook Peak Performance on Instagram  

A story about Familial HypercholesterolemiaThe importance of coronary artery calcium scoring in determining the need for a statinA weedkiller worse than glyphosate being used in the USCan I eat one meal a day indefinitely?

Alzheimer's disease is constantly surrounded by myths and misinformation. Let's set the record straight. In this episode, we bust through the most persistent Alzheimer's myths, with facts based on decades of clinical experience and cutting-edge research. Myths include: • “Alzheimer's is inevitable in old age” • “It's all genetic, and there's nothing you can do” • “There's no cure, so diagnosis is useless” • “Supplements and vitamins can prevent or cure Alzheimer's” • “Statins and vaccines cause Alzheimer's” Plus many others. We also share our science-backed insights and practical tips for helping you prevent cognitive decline, starting TODAY. ‘Your Brain On... Alzheimer's (Mythbusting Special)' • SEASON 5 • EPISODE 9 SUPPORTED BY: NEURO World. Help your brain thrive, now and into the future: https://neuro.world/ ‘Your Brain On' is hosted by neurologists, scientists, and public health advocates Ayesha and Dean Sherzai. CONNECT WITH THE BRAIN DOCS Website: https://thebraindocs.com/ Instagram: https://www.instagram.com/thebraindocs TikTok: https://www.tiktok.com/@thebraindocs

Gil and Eric discuss Eric's book, Super Agers, and the inspiration behind it: a 98-year-old patient who exemplified healthy aging. They explore the five dimensions of healthspan optimization: lifestyle, omics, the immune system, and the role of data and AI in personalized medicine. Eric highlights how AI can analyze multi-layered data to provide personalized recommendations for preventing age-related diseases.The conversation also explores the importance of exercise, sleep, and social connection for healthy aging, as well as the risks associated with high-dose statins. Eric emphasizes the need for a shift towards preventative care, using data and AI to identify and address individual risks. He stresses the power of lifestyle changes, rather than supplements, in improving long-term health outcomes.  Guest-at-a-Glance 

Thanks to our Partners, NAPA Auto Care and NAPA TRACS Recorded at the TST Big Event, John Anello passionately advocates for holistic health and nutrition, drawing from personal experiences and research. He shares practical tips on balanced eating, the power of natural, unprocessed foods like homemade beet juice, and the benefits of exercise and lifestyle choices for longevity and disease prevention. The conversation sheds light on common health challenges in the automotive industry and encourages listeners to take charge of their well-being through regular health monitoring, proactive self-care, and informed dietary decisions. Show Notes Watch Full Video Episode TST Big Event 2025: https://www.tstseminars.org/ Introduction (00:00:00) John's Background and Early Health Observations (00:01:56) COVID-19 as a Catalyst for Health Focus (00:05:56) Observations in Automotive Shops (00:07:43) Proactive Health Diagnostics (00:09:25) Body Aging, Stress, and Diet Fundamentals (00:13:34) Moderation and Understanding Nutrition (00:15:01) Cholesterol, Brain Health, and Immune Chicken Recipe (00:16:26) Supplements, Sunlight, and Exercise (00:24:12) Medication, Longevity, and Statins (00:26:26) Meal Prep, Containers, and Italian Diet (00:29:01) Sugar, Diabetes, and Electric Food (00:30:47) Discipline, Regimen, and Sleep (00:35:51) Organic Food, Farming Practices, and Minerals (00:38:01) Detoxing, Chemical Exposure, and Testing (00:41:01) Doctors, Pharmaceuticals, and Personal Choice (00:42:58) Dental Health and Natural Remedies (00:43:52) Thanks to our Partners, NAPA Auto Care and NAPA TRACS Learn more about NAPA Auto Care and the benefits of being part of the NAPA family by visiting https://www.napaonline.com/en/auto-care NAPA TRACS will move your shop into the SMS fast lane with onsite training and six days a week of support and local representation. Find NAPA TRACS on the Web at http://napatracs.com/ Connect with the Podcast: Follow on Facebook: https://www.facebook.com/RemarkableResultsRadioPodcast/ Join Our Virtual Toastmasters Club: https://remarkableresults.biz/toastmasters Join Our Private Facebook Community: https://www.facebook.com/groups/1734687266778976 Subscribe on YouTube: https://www.youtube.com/carmcapriotto Follow on LinkedIn: https://www.linkedin.com/in/carmcapriotto/ Follow on Instagram:

To Find Deplorable Janet--> https://open.spotify.com/show/3K5Xi9LugxNdI06GXSIjAp?si=m5hPD7OsS6eim1jACk84ewTo sign up for our Patreon go to-> Patreon.com/cultofconspiracypodcast To Join the Cajun Knight Patreon---> Patreon.com/cajunknight To Find The Cajun Knight Youtube Channel---> click hereTo Invest In Gold & Silver, CHECK OUT—-> Www.Cocsilver.com 10% OFF Rife Machine---> https://rifemachine.myshopify.com/?rfsn=7689156.6a9b5c To find the Meta Mysteries Podcast---> https://open.spotify.com/show/6IshwF6qc2iuqz3WTPz9Wv?si=3a32c8f730b34e79 50% OFF Adam&Eve products---> :adameve.com (promo code : CULT) To Sign up for our Rokfin go to --> Rokfin.com/cultofconspiracy Cult Of Conspiracy Linktree ---> https://linktr.ee/cultofconspiracyBecome a supporter of this podcast: https://www.spreaker.com/podcast/cult-of-conspiracy--5700337/support.

Join us as we review recent practice-changing articles on the effect of combination statin and ezetimibe in reducing myalgias, male partner treatment for BV, semaglutide for MASH/liver fibrosis, exercise and cancer risk, and cytisinicline for smoking cessation. Fill your brain hole with some delicious apps and entrees from our spring Digests! Featuring Paul Williams (@PaulNWilliamz), Nora Taranto (@norataranto), special guest epidemiologist Alexander Chaitoff (@alexchaitoff) and Matt Watto (@doctorwatto). Claim CME for this episode at curbsiders.vcuhealth.org! Patreon | Episodes | Subscribe | Spotify | YouTube | Newsletter | Contact | Swag! | CME Credits Written and Hosted by: Nora Taranto MD; Alexander Chaitoff MD, MPH; Paul Williams, MD, FACP, Matthew Watto MD, FACP, Alex Chaitoff MD MPH  Cover Art: Nora Taranto MD Reviewer: Leah Witt MD  Technical Production: Pod Paste Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP Show Segments Intro, disclaimer Self-collected HPV tests for cervical cancer screening  Semaglutide for MASH/Liver Fibrosis Male Partner Treatment for BV  Statins plus ezetimibe versus high-dose statins alone for statin-associated muscle symptoms  Exercise and Colon Cancer Risk  Cytisinicline for Smoking Cessation  Outro Sponsor: FIGS Curbsiders listeners can get 15% off. Just go to wearFIGS.com and use code FIGSRX Sponsor: Quince Go to Quince.com/curb for free shipping on your order and 365 day returns.  Sponsor: Continuing Education Company Curbsiders listeners get 45% off select online courses with promo code Curb45, through July 30. You can also use Curb30 for 30% off all webcasts and on demand replay courses. Check it all out at CMEmeeting.org/curbsiders.

[01:23:16 – 01:27:24] — Cholesterol Myth, Statins, and Cognitive Decline Refutes the link between cholesterol and heart disease, critiques the use of statins, and explains how they contribute to memory loss by impairing mitochondrial function. [01:40:53 – 01:43:33] — Spike Protein Damage and Fertility Concerns Links mRNA vaccine-induced spike protein accumulation in reproductive organs to a global fertility crisis, citing observed autoimmune diseases and turbo cancer cases post-vaccination.[01:53:29 – 01:58:27] — Treating Vaccine Clotting with Enzymes and NAC Outlines a protocol using enzymes like lumbrokinase and an enhanced NAC formulation to reverse microclotting and spike protein persistence in long-haul COVID patients.[01:58:29 – 01:59:39] — Bacteriophages and Antibiotic Resistance Praises bacteriophage therapy as a targeted alternative to antibiotics and criticizes its abandonment in favor of pharmaceuticals, linking this to rising antimicrobial resistance.[02:01:26 – 02:04:38] — SSRIs, Mental Health, and Nutrient Deficiencies Critiques widespread SSRI prescriptions, emphasizing magnesium, iodine, and vitamin D deficiencies as underlying causes of depression and anxiety in young patients.[02:14:43 – 02:17:31] — SSRI Withdrawal, Loneliness, and Atheism Trends Explores the challenges of getting off SSRIs, with emphasis on individualized treatment and social patterns such as loneliness, atheism, and lack of purpose among depressed patients.[02:26:27 – 02:29:41] — Immune System Boosting and Sunshine Debate Advocates sunlight and antioxidant synergy (e.g. ALA, vitamin C, CoQ10) as immune boosters; challenges conventional views on sunlight causing skin cancer, linking melanoma instead to lack of sun exposure.[02:31:28 – 02:40:14] — DMSO and Boron for Pain, Bone, and Hormonal Health Promotes DMSO combined with boron for arthritis and testosterone boosting; includes detailed background on absorption, safety, and additional applications.[02:40:15 – 02:45:19] — Leaky Gut as Root of Autoimmune Disease Describes how gluten-related intestinal damage can lead to autoimmune diseases like rheumatoid arthritis and Hashimoto's; outlines a multi-supplement gut-healing protocol.[03:00:25 – 03:03:54] — Medical Industrial Complex and Generational Health Decline Critiques a profit-driven healthcare model that fosters chronic illness for repeat business and links rising childhood illness and birth defects to vaccine exposure and poor nutrition.[03:06:12 – 03:17:16] — Thyroid Dysfunction and Comprehensive Testing Approach Explains the biochemical complexity of thyroid function and criticizes mainstream thyroid testing, advocating for broader lab panels and natural hormone therapies.[03:20:16 – 03:23:19] — Blue Light, Circadian Rhythm, and Melatonin Suppression Describes how artificial lighting and sunglasses disrupt melatonin production, emphasizing the need for natural sunlight exposure and avoidance of electronics during sleep.[03:48:28 – 03:52:20] — Economic Collapse, Oil Crisis, and CBDC Transition Argues that current global conflict and economic chaos are engineered to collapse the dollar, spike oil prices, and drive public acceptance of central bank digital currencies.[03:59:24 – 04:00:05] — Grassroots Support for Independent Media Encourages community-driven funding of alternative media, rejecting corporate censorship and highlighting the role of listener support in sustaining truthful broadcasting. Follow the show on Kick and watch live every weekday 9:00am EST – 12:00pm EST https://kick.com/davidknightshow Money should have intrinsic value AND transactional privacy: Go to https://davidknight.gold/ for great deals on physical gold/silver For 10% off Gerald Celente's prescient Trends Journal, go to https://trendsjournal.com/ and enter the code KNIGHT Find out more about the show and where you can watch it at TheDavidKnightShow.comIf you would like to support the show and our family please consider subscribing monthly here: SubscribeStar https://www.subscribestar.com/the-david-knight-showOr you can send a donation throughMail: David Knight POB 994 Kodak, TN 37764Zelle: @DavidKnightShow@protonmail.comCash App at: $davidknightshowBTC to: bc1qkuec29hkuye4xse9unh7nptvu3y9qmv24vanh7Become a supporter of this podcast: https://www.spreaker.com/podcast/the-david-knight-show--2653468/support.

[01:23:16 – 01:27:24] — Cholesterol Myth, Statins, and Cognitive Decline Refutes the link between cholesterol and heart disease, critiques the use of statins, and explains how they contribute to memory loss by impairing mitochondrial function. [01:40:53 – 01:43:33] — Spike Protein Damage and Fertility Concerns Links mRNA vaccine-induced spike protein accumulation in reproductive organs to a global fertility crisis, citing observed autoimmune diseases and turbo cancer cases post-vaccination.[01:53:29 – 01:58:27] — Treating Vaccine Clotting with Enzymes and NAC Outlines a protocol using enzymes like lumbrokinase and an enhanced NAC formulation to reverse microclotting and spike protein persistence in long-haul COVID patients.[01:58:29 – 01:59:39] — Bacteriophages and Antibiotic Resistance Praises bacteriophage therapy as a targeted alternative to antibiotics and criticizes its abandonment in favor of pharmaceuticals, linking this to rising antimicrobial resistance.[02:01:26 – 02:04:38] — SSRIs, Mental Health, and Nutrient Deficiencies Critiques widespread SSRI prescriptions, emphasizing magnesium, iodine, and vitamin D deficiencies as underlying causes of depression and anxiety in young patients.[02:14:43 – 02:17:31] — SSRI Withdrawal, Loneliness, and Atheism Trends Explores the challenges of getting off SSRIs, with emphasis on individualized treatment and social patterns such as loneliness, atheism, and lack of purpose among depressed patients.[02:26:27 – 02:29:41] — Immune System Boosting and Sunshine Debate Advocates sunlight and antioxidant synergy (e.g. ALA, vitamin C, CoQ10) as immune boosters; challenges conventional views on sunlight causing skin cancer, linking melanoma instead to lack of sun exposure.[02:31:28 – 02:40:14] — DMSO and Boron for Pain, Bone, and Hormonal Health Promotes DMSO combined with boron for arthritis and testosterone boosting; includes detailed background on absorption, safety, and additional applications.[02:40:15 – 02:45:19] — Leaky Gut as Root of Autoimmune Disease Describes how gluten-related intestinal damage can lead to autoimmune diseases like rheumatoid arthritis and Hashimoto's; outlines a multi-supplement gut-healing protocol.[03:00:25 – 03:03:54] — Medical Industrial Complex and Generational Health Decline Critiques a profit-driven healthcare model that fosters chronic illness for repeat business and links rising childhood illness and birth defects to vaccine exposure and poor nutrition.[03:06:12 – 03:17:16] — Thyroid Dysfunction and Comprehensive Testing Approach Explains the biochemical complexity of thyroid function and criticizes mainstream thyroid testing, advocating for broader lab panels and natural hormone therapies.[03:20:16 – 03:23:19] — Blue Light, Circadian Rhythm, and Melatonin Suppression Describes how artificial lighting and sunglasses disrupt melatonin production, emphasizing the need for natural sunlight exposure and avoidance of electronics during sleep.[03:48:28 – 03:52:20] — Economic Collapse, Oil Crisis, and CBDC Transition Argues that current global conflict and economic chaos are engineered to collapse the dollar, spike oil prices, and drive public acceptance of central bank digital currencies.[03:59:24 – 04:00:05] — Grassroots Support for Independent Media Encourages community-driven funding of alternative media, rejecting corporate censorship and highlighting the role of listener support in sustaining truthful broadcasting. Follow the show on Kick and watch live every weekday 9:00am EST – 12:00pm EST https://kick.com/davidknightshow Money should have intrinsic value AND transactional privacy: Go to https://davidknight.gold/ for great deals on physical gold/silver For 10% off Gerald Celente's prescient Trends Journal, go to https://trendsjournal.com/ and enter the code KNIGHT Find out more about the show and where you can watch it at TheDavidKnightShow.comIf you would like to support the show and our family please consider subscribing monthly here: SubscribeStar https://www.subscribestar.com/the-david-knight-showOr you can send a donation throughMail: David Knight POB 994 Kodak, TN 37764Zelle: @DavidKnightShow@protonmail.comCash App at: $davidknightshowBTC to: bc1qkuec29hkuye4xse9unh7nptvu3y9qmv24vanh7Become a supporter of this podcast: https://www.spreaker.com/podcast/the-real-david-knight-show--5282736/support.

PhD in synthetic chemistry, the Product Formulator for Supplement Needs, and fitness industry renowned Pharmacologist for his no-nonsense approach in bodybuildingThe Bodybuilding-friendly HRT Clinic - Get professional medical guidance on peptides AND optimizing your health as a man or bodybuilder:[ Pharma Test, IGF1, Tesamorelin, Glutathione, BPC, Semaglutide, Var troche, etc]https://transcendcompany.com/patient-intake-form/?ls=Nyle+NaygaWatch it: https://www.youtube.com/watch?v=6Ihq4tIzyS8&t=5618sRP Hypertrophy Training App: rpstrength.com/nylePlease share this episode if you liked it. To support the podcast, the best cost-free way is to subscribe and please rate the podcast 5* wherever you find your podcasts. Thanks for watching.To be part of any Q&A, follow trensparentpodcast or nylenayga on instagram and watch for Q&A prompts on the story  https://www.instagram.com/trensparentpodcast/Huge Supplements (Protein, Pre, Defend Cycle Support, Utilize GDA, Vital, Astragalus, Citrus Bergamot): https://www.hugesupplements.com/discount/NYLESupport code 'NYLE' 10% off - proceeds go towards upgrading content productionYoungLA Clothes: https://www.youngla.com/discount/nyleCode ‘NYLE' to support the podcastLet's chat about the Podcast:Instagram: https://www.instagram.com/trensparentpodcast/TikTok: https://www.tiktok.com/@transparentpodcastPersonalized Bodybuilding Program:  https://www.nylenaygafitness.com2:19 Bodybuilding Pharmacology and Dosing4:53 Brain Health and Long-Term Risks7:29 Muscle Building and Genetic Factors10:03 Cholesterol and LDL Impacts12:14 Podcast Setup and Equipment Upgrades14:34 Hair Transplant Journey24:23 Hair Loss Causes and Treatments34:59 Post-Transplant Recovery and Rebound39:31 Epigenetics and Muscle Memory43:04 Ethical Questions on Genetic Enhancement45:40 Enhanced Games Debate50:09 Dosing Challenges in Enhanced Sports52:32 Data Collection and Human Experimentation55:16 Genetic Variance and Elite Athletes59:04 Neurodegeneration and PEDs1:07:08 Oxidative Stress in Bodybuilding1:09:37 Sleep and Brain Detox1:18:01 Nutrition for Oxidative Stress1:19:02 Melatonin as an Antioxidant1:21:13 Melatonin Dosing and Effects1:24:51 Melatonin and Sleep Support Supplements1:28:22 Magnesium and Sleep Health1:31:23 Sleep Apnea and Neural Health1:36:30 Frequent Urination at Night1:46:33 Overheating During Sleep1:59:14 Wrapping Up Oxidative Stress2:00:33 Neuron Loss and Neurotransmitters2:02:04 Boosting Brain Health with BDNF2:04:08 Peptides for Neural Growth2:09:14 Oxidative Stress and Supplements2:12:34 Neuroprotection Strategies2:19:56 EMF and Environmental Stressors2:22:12 Mitochondrial Dysfunction and Aging2:24:55 Balancing Oxidative Stress2:28:32 Steroids and Muscle Growth Rates2:38:54 HDL and LDL Control Ancillaries2:41:34 Statins and LDL Oxidation2:47:36 Antioxidants and Plaque Formation2:54:10 Balancing Cholesterol Levels2:58:35 CT Scans for Heart Health3:03:54 Heart Health Supplements3:06:48 Mitochondrial Stack Under 303:16:27 Balanced Diet in Prep3:20:24 Omega-3 and Fish Oil Quality3:23:36 Podcast Wrap-Up

We're digging into egg health, inflammation, and the key factors that cause it. We often hear about “low AMH” or “poor egg quality” without answers that go beneath the surface. In today's episode, we explore a missing link that could be driving it all: chronic inflammation. Whether you're dealing with diminished ovarian reserve (DOR), premature ovarian insufficiency (POI), or recurrent miscarriage, understanding inflammation's role may be key to moving forward. This episode is for anyone ready to connect the dots between lab results, symptoms, and what's going on inside the body. If you've been told everything is “normal,” but it doesn't feel that way, this is your invitation to dig deeper with science, strategy, and a plan. This episode is for you if: You're struggling with low AMH, diminished ovarian reserve (DOR), or poor egg quality. You want to understand how inflammation could be impacting your fertility journey. You're looking for actionable insights to support egg health naturally through lab markers and lifestyle factors. In this episode you'll learn: How chronic inflammation affects egg quality, ovarian reserve, and miscarriage risk Why low AMH isn't the full story and what labs to ask for next Key blood markers (like hs-CRP, homocysteine, and thyroid antibodies) that reveal hidden inflammation The role of insulin resistance, thyroid imbalance, and nutrient deficiencies in ovarian aging Practical strategies to reduce inflammation and improve egg health with a functional approach --- RESOURCES "Your Labs Are Normal” But Are They? 20 Overlooked Blood Markers & Functional Tests to Improve Egg Quality & Fertility:  https://fabfertile.com/blogs/podcasts/your-labs-are-normal-but-are-they-20-overlooked-blood-markers-functional-tests-to-improve-egg-quality-fertility Why Does It Matter If I Have Migraines and POI?: https://fabfertile.com/blogs/podcasts/why-does-it-matter-if-i-have-migraines-and-poi?_pos=2&_sid=27548216b&_ss=r The Link Between Sleep and Fertility: Why Getting Enough Rest Matters:  https://fabfertile.com/blogs/podcasts/how-poor-sleep-could-be-sabotaging-your-egg-quality Why Addressing Homocysteine Levels Can Boost Egg and Sperm Health: https://fabfertile.com/blogs/podcasts/why-addressing-homocysteine-levels-can-boost-egg-and-sperm-health?_pos=1&_sid=750cbcc5e&_ss=r What Mood Swings, Sugar Cravings, Poor Sleep and Feeling Hangry Have to Do With Your Fertility:  https://fabfertile.com/blogs/podcasts/what-mood-swings-sugar-cravings-poor-sleep-and-feeling-hangry-has-to-do-with-your-fertility?_pos=11&_sid=02696b0e2&_ss=r Why Genomic Testing Can Help With Recurrent Pregnancy Loss, Birth Outcomes and Preconception Health:  https://fabfertile.com/blogs/podcasts/why-genomic-testing-can-help-with-recurrent-pregnancy-loss-birth-outcomes-and-preconception-health?_pos=10&_sid=8a66db686&_ss=r Is Your Thyroid Impacting Egg Health? The Hidden Connection to Low AMH, DOR & Fertility Success:  https://fabfertile.com/blogs/podcasts/is-your-thyroid-impacting-egg-health-the-hidden-connection-to-low-amh-dor-fertility-success?_pos=6&_sid=96ccbdc87&_ss=r Low AMH? Why 'Normal' Vitamin D Levels May Still Be Hurting Your Egg Quality:  https://fabfertile.com/blogs/podcasts/low-amh-why-normal-vitamin-d-levels-may-still-be-hurting-your-egg-quality?_pos=4&_sid=4de32e2e0&_ss=r The Intricate Dance: Cholesterol, Statins, and Fertility: https://fabfertile.com/blogs/education/the-intricate-dance-cholesterol-statins-and-fertility?_pos=1&_sid=2948a9d48&_ss=r Our favorite fertility tracker (use code FABFERTILE15 to save 15): https://www.inito.com/en-us/?srsltid=AfmBOoo85sXu_esmFN5Kz6iysaTkBKgYl35Jubv-BaLkkxXVggdk6nes Fab Fertile Method https://www.fabfertile.com/what-we-do/ Ultimate Guide to Getting Pregnant This Year If You Have Low AMH/High FSH - https://fabfertile.clickfunnels.com/optinvbzjfsii Not sure where to start? Book a 15-minute call here and we'll give you options to help. ---

In this episode of Quality Talks With Peggy O'Kane, NCQA President Peggy O'Kane sits down with Dr. Rita Redberg, a cardiology pioneer and fierce advocate for evidence-based care. Dr. Redberg, who famously served as Editor-in-Chief of JAMA Internal Medicine for 14 years, shares her "Less is More" philosophy — a perspective that challenges the view that "more" care is always better.Join Peggy and Rita as they explore:The Problem with "More": Why a health care culture focused on technology and volume over patient needs leads to runaway costs and poor results.The Stent Story: How a widely adopted procedure in cardiology gained traction without initial evidence of patient benefit, and the uphill battle to integrate rigorous clinical trials.Mary Caldwell's Odyssey: A cautionary tale illustrating the dangerous cascade of unnecessary testing and interventions, based on a desire for reassurance rather than clinical need.Re-evaluating Statins: Rita's unconventional view on the use of statins in asymptomatic people. She advocates lifestyle changes over medication when the evidence of benefit is thin.Rebuilding Trust: How the fee-for-service payment model erodes the patient-doctor relationship and how regulatory reforms can shift incentives towards patient wellbeing.Rita reminds us that health care quality isn't about more tests or interventions. It's about thoughtful, patient-centered decisions and a commitment to "first, do no harm." This episode is a must-listen for anyone curious about improving health outcomes and reducing waste in health care.Key Quote:Most statins are prescribed for people that have not already had a heart attack or have established coronary disease. In that higher risk group, there is some benefit to taking statins. It's not huge but there is some benefit.But most people I see, and most people taking statins, are not in that category. They're healthy people that want to prevent a heart attack and want to live longer. They definitely are not going to feel better. Rita Redberg, MDTime Stamps:(02:09) Misconceptions in Medicine(10:01) Mary Caldwell: A Cautionary Tale(13:35) Choosing Wisely Campaign: A Step Towards Better Care(16:32) Debating the Use of Statins(21:31) Trust, Incentives and the High Cost of US Care(27:05) Technology, Teams and Trust Links:JAMA Internal Medicine “Less is More”Choosing WiselyConnect with Rita

Story at-a-glance Cholesterol is essential for hormone production, brain function, and cell health, and about 80% of it is made by your body — not consumed in food. High triglycerides, not total cholesterol, pose a stronger risk for heart attack — raising risk by 80% — making triglyceride-to-HDL ratio a better heart disease predictor Newer science shows chronic inflammation — not LDL alone — may be the real cause of plaque buildup in arteries, shifting focus to markers like ApoB and CRP Natural options like garlic, artichoke, bergamot, plant sterols, green tea, and oats have been shown in clinical studies to lower LDL cholesterol and improve heart markers Red yeast rice can lower LDL by up to 33%, but it contains a statin-like compound with the same side effects and potential kidney toxins like citrinin Lifestyle changes like cutting sugar, walking daily, and sleeping well can activate the Pareto Principle — where 20% of effort yields 80% of results in lowering cholesterol. Exercise improves five key metabolic biomarkers — glucose, HDL, triglycerides, blood pressure, and waist size — each linked to long-term cardiovascular health

Welcome back to our weekend Cabral HouseCall shows!   This is where we answer our community's wellness, weight loss, and anti-aging questions to help people get back on track!   Check out today's questions:     Kellie: Hi Dr. Cabral! I have been with your program for almost 6 months now. I have completed the Vit-Tox tests and have gone through the FM Detox twice and now going through the CBO Protocol. I just turned 38 years old and I feel like my joints are of an 80 year old. I have played soccer since age 5 and still play on a competitive coed league to this day. I have played many other team/contact sports in the past. I have had past ankle, knee, and hip injuries due to sports and I do see possible knee and hip replacements in my future. When I do my daily workouts or go up/down stairs my ankles, knees, hips, and back crack or pop so easily and so much. I don't see glucosamine chondroitin as a supplement in your shop. Are there any suggestions you may have to keep my joints healthier? Thank you!!              Jon: Hey Dr Cabral, looking for advice and i feel like there's a population that struggles with this same topic. My Dr is recommending a statin due to my high LDL-C of 230. My LDL has gone up after cleaning up my diet in the last 7 months however ALL of my markers tested for have improved. Triglycerides have gone from over 200 to 100, HDL is up to 60, VLDL has dropped from 30 to 15, A1C is 5.2, blood pressure is normal for the first time ever, and so onr. My personal opinion is that i'm healthier than ever and i can't imagine having to go on what seems like a lifetime drug due to one marker being off and i don't buy the story that LDL alone is a concern for me. Curious on your opinion here and if you think i have something to worry about. Thanks!!                                                                                                                            Annette: I've been diagnosed with nephrocalcinosis by conventional doctors who say the cause is genetic. I have adjusted my diet to low sodium, low oxalate foods. The doctors say my next step is to try to get on the kidney transplant list before I need dialysis. I take potassium citrate and a calcitriol. Is there anything I can do to improve my kidney function?                                                                                                  Summer: Hi Dr. Cabral! I heard you say that it's best to replace aluminum cookware, but not necessary, and instead to use parchment paper as a barrier. Doesn't the aluminum off gas when heated? How does parchment paper prevent the aluminum from getting into the food? Thanks! By the way, to all my fellow listeners: please contact your state representatives and let them know you do not consent to geo-engineering in your skies. Several states have now banned it. We could all live healthier lives if we could work toward eliminating toxins and heavy metals including aluminum that are regularly being sprayed into our air.                                                                                                                                                Ann: Thank you Dr Cabral- you are changing SO many lives - thank you for all of your wisdom and teachings:) I have a question about Magnesium. My cortisol was high at my last lab test, and I took Full Spectrum magnesium for 12 weeks, and now I take Cal Mag daily. I also understand that I can take Calming Magnesium and CBD at night to help with sleep.I don't want to take too much for too long for my body, but I still think I need the help for my cortisol levels/ sleep. What combination of the above do you recommend? Is there a length of time that is too long to be on Full Spectrum Magnesium? PS. I do the 3-2-1 protocol, take Adrenal Soothe and will be repeating my big 5 this fall. Thank you again!           Thank you for tuning into today's Cabral HouseCall and be sure to check back tomorrow where we answer more of our community's questions!      - - - Show Notes and Resources: StephenCabral.com/3396 - - - Get a FREE Copy of Dr. Cabral's Book: The Rain Barrel Effect - - - Join the Community & Get Your Questions Answered: CabralSupportGroup.com - - - Dr. Cabral's Most Popular At-Home Lab Tests: > Complete Minerals & Metals Test (Test for mineral imbalances & heavy metal toxicity) - - - > Complete Candida, Metabolic & Vitamins Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Complete Stress, Mood & Metabolism Test (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Complete Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Complete Omega-3 & Inflammation Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels) - - - Get Your Question Answered On An Upcoming HouseCall: StephenCabral.com/askcabral - - - Would You Take 30 Seconds To Rate & Review The Cabral Concept? 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If you want glowing, youthful skin, you must work from the inside out. Discover one of the best anti-aging foods for your skin to add to your diet today! 0:00 Introduction: How to look younger 1:46 The best anti-aging food4:27 Collagen and anti-aging4:52 The best anti-aging diet Is your beauty routine actually aging you? The creams and lotions you think are helping your skin could have plastics, toxic chemicals, and hidden carcinogens. Even the products containing collagen will not be absorbed topically through the skin.Over-cleansing and excess scrubbing destroy your skin's microbiome. Tap water contains fluoride and chlorine, which are toxic and damaging to the skin. A filter for your shower can help.Statins can also destroy youthful skin. They block cholesterol, which is essential for skin health and integrity. The FDA does not do third-party testing on the chemicals in your anti-aging products. The EU has banned 1600 cosmetic ingredients, while the US has only banned 30. The best anti-aging food is high in retinol, an essential building block for connective tissue and vital for the skin's immune function. This anti-aging food contains copper and zinc, which support skin elasticity and healing. It's loaded with iron, and a single serving has more anti-wrinkle and anti-aging benefits than many expensive creams. If you haven't guessed, grass-fed liver is the #1 anti-aging superfood! Grass-fed liver contains every cofactor and nutrient necessary for healthy, youthful skin. Some people don't enjoy eating liver, and if you have preexisting liver damage, you may feel tired after eating it. If this happens, try taking one beef liver capsule before bed. Soaking liver in lemon juice can improve its taste. Many good recipes also make it more palatable. Liver pâté, grass-fed liver pills, and blending liver with ground beef can also help mask the flavor. If you consume collagen, you need many cofactors to penetrate the skin. Liver provides all of them!Ultraprocessed foods will make you look older! Low-fat diets can also have an aging effect on the skin. Low-fat protein and poor quality protein will help you lose weight, but won't help you look younger. Dr. Eric Berg DC Bio:Dr. Berg, age 60, is a chiropractor who specializes in Healthy Ketosis & Intermittent Fasting. He is the author of the best-selling book The Healthy Keto Plan, and is the Director of Dr. Berg Nutritionals. He no longer practices, but focuses on health education through social media.

Story at-a-glance Nearly 40 million Americans take statins daily, yet these drugs don't fix the root cause of high cholesterol and often cause serious side effects like muscle pain and insulin resistance Dr. Adriana Quinones-Camacho, a cardiologist at NYU Langone Health, recommends lifestyle changes — like eating clean fats, exercising, and losing weight — as first-line treatments before resorting to risky cholesterol-lowering medications Eliminating processed seed oils and consuming whole-food omega-3s from fatty fish (in optimal amounts) will help improve your lipid profile and support natural cholesterol clearance through liver and cell function Excess weight raises low-density lipoprotein (LDL) levels and leads to plaque buildup in arteries; reducing sugar, increasing fiber, and adding daily movement reverses this damage and promotes long-term cardiovascular health Statins are linked to diabetes, cataracts, muscle breakdown, and depleted CoQ10, making lifestyle changes not only safer but also more effective for lasting heart and metabolic health

In this episode of the Smarter Not Harder Podcast, Dr. Abid Husain joins Dr. Scott Sherr for a masterclass on cardiovascular health — from cholesterol myths to mitochondrial truth. They explore what truly drives inflammation, plaque formation, and cardiovascular risk, while dismantling the outdated “cholesterol = heart disease” narrative. Whether you're a clinician or simply someone trying to make smarter choices for your heart, this episode offers insight into testing, interventions, and personalized strategies that go beyond basic lipid panels. Join us as we delve into: + Why LDL alone doesn't tell the full story of cardiovascular risk + How mitochondria, hormones, and inflammation intersect with lipid metabolism + The real role of CCTA scans, plaque imaging, and particle size analysis + Advanced medications and peptides that support vascular and metabolic health This episode is for you if: - You've been told to fear cholesterol but want the full picture - You're a practitioner looking to personalize cardiovascular treatment plans - You've heard of statins and PCSK9s but don't know when or why to use them - You're curious about GLP-1s, NO precursors, and other precision tools for heart health You can also find this episode on… YouTube: https://youtu.be/npYvJS2cpGc Find more from Dr. Abid Husain: Boulder Longevity: https://boulderlongevity.com LinkedIn: https://www.linkedin.com/in/abid-husain-md-facc-abaarm-00874419/ Find more from Smarter Not Harder: Website: https://troscriptions.com/blogs/podcast | https://homehope.org Instagram: @troscriptions | @homehopeorg Get 10% Off your purchase of the Metabolomics Module by using PODCAST10 at https://www.homehope.org Get 10% Off your Troscriptions purchase by using POD10 at https://www.troscriptions.com Get daily content from the hosts of Smarter Not Harder by following @troscriptions on Instagram.