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In this episode, preventive cardiologist Dr. Ann Marie Navar, a member of the committee that helped shape the American Heart Association's new recommendations for earlier cholesterol management, explains why many experts believe cardiovascular prevention should begin decades before most people ever experience symptoms. Dr. Navar explains why lowering LDL cholesterol earlier in life can have lasting benefits decades later, how ApoB and lipoprotein(a) are reshaping the way experts think about heart disease risk, and why some of the most popular fears surrounding statins aren't supported by the evidence. The conversation also explores the growing divide between evidence-based medicine and the wellness industry and the challenges of separating compelling biological theories from treatments that have actually been proven to improve health outcomes. She's a wealth of knowledge and a wonderful guest. Hope you enjoy.
This week, Marianna sits down with John Faragon to talk about the latest updates to HIV diagnoses, deaths, and prevalence, along with new information on statin use for people with HIV.-- Help us track the number of listeners our episode gets by filling out this brief form! (https://www.e2NECA.org/?r=AQX7941)--Want to chat? Email us at podcast@necaaetc.org with comments or ideas for new episodes. --Check out our free online courses: www.necaaetc.org/rise-courses--Download our HIV mobile apps:Google Play Store: https://play.google.com/store/apps/developer?id=John+Faragon&hl=en_US&gl=US Apple App Store: https://apps.apple.com/us/developer/virologyed-consultants-llc/id1216837691
View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter Tom Dayspring is a world-renowned lipidologist and one of the most thoughtful teachers in the field of lipid metabolism. In this episode, Tom returns to The Drive for a deep dive into the relationship between lipids and brain health, beginning with the fundamentals of cholesterol transport before exploring why the brain's cholesterol system operates almost entirely independently from the rest of the body. Tom examines the roles of apoB, apoA-I, and especially apoE in cholesterol homeostasis, discusses how APOE genotype influences Alzheimer's disease risk, and unpacks the complex links between cholesterol metabolism, amyloid, and tau pathology. He also reviews what is currently known—and still uncertain—about the effects of statins, ezetimibe, omega-3 fatty acids, and emerging CETP inhibitors on brain health and neurodegenerative disease risk. Although highly technical, this conversation provides an essential framework for understanding the nuanced relationship between lipid-lowering therapies, cardiovascular disease prevention, and neurodegenerative diseases in an area often clouded by misinformation. We discuss: The fundamentals of cholesterol transport in the body, and how peripheral cholesterol metabolism differs from cholesterol handling in the brain [2:45]; How cholesterol is transported through plasma and stored within cells, and why lowering LDL cholesterol does not deplete the body or brain of cholesterol [11:45]; How apoB particles drive atherosclerosis, why lowering lipids matters, and the factors that influence individual cardiovascular risk [20:00]; How the brain produces and transports its own cholesterol using apoE lipoproteins independently of circulating cholesterol and apoB-containing lipoproteins [29:00]; How apoB structure influences LDL receptor binding and LDL clearance [39:00]; How neurons acquire cholesterol from apoE-containing lipoproteins and why desmosterol serves as a unique marker of cholesterol synthesis in the brain [41:45]; The difference between the APOE gene and the apoE protein, the major APOE genotypes found in humans, and how APOE4 influences Alzheimer's disease risk [48:45]; HDL function beyond cholesterol: immune function, protein cargo, and communication with the brain [53:30]; How APOE4-associated defects in brain cholesterol transport may promote Alzheimer's disease: amyloid production, neuronal cholesterol homeostasis, and cholesterol clearance [58:00]; Statins and brain health: reviewing the evidence of the potential impact of statins on cognition and Alzheimer's disease risk [1:09:00]; Desmosterol and 24S-hydroxycholesterol as biomarkers of brain cholesterol metabolism and statin effects [1:17:15]; Possible cognitive benefits of ezetimibe beyond lowering apoB [1:19:30]; EPA, DHA, and the evidence for omega-3 fatty acids in brain health [1:23:15]; Obicetrapib: an emerging CETP inhibitor with potential implications for both cardiovascular and brain health [1:31:00]; and More. Connect With Peter on Twitter, Instagram, Facebook and YouTube
The “Enhanced Games”, with no-holds-barred performance-enhancing drugs, yields scant advantages over “clean” contests; Does saturated fat increase insulin resistance? Can a heart attack victim avoid statin use with CoQ10? Omega-3 fish oil shows promise vs. type 2 diabetes; Motorized e-scooter use needs to be regulated NOW!
If you've ever left a doctor's appointment thinking, "That answered exactly none of my questions," this episode is for you. This week, I'm joined by fellow physician assistant and functional medicine practitioner Shelly Satizabal for a candid conversation about perimenopause, hormone replacement therapy (HRT), birth control, statins, medical gaslighting, and women's health. We discuss why so many women are told they're "too young" for perimenopause, why symptoms get dismissed despite "normal" labs, and how women continue to fall through the cracks of a healthcare system that historically wasn't designed around female physiology. We also dive into hormones, cholesterol, statins, women's health research, and why asking questions shouldn't make you a difficult patient. If you've ever felt unheard, brushed off, or like nobody is interested in finding the root cause of your symptoms, this conversation is for you. Learn more about working with me Shop my masterclasses (learn more in 60-90 minutes than years of dr appointments) Follow me on IG Follow Empowered Mind + Body on IG Learn More About Shelly here Follow Shelly on IG
Heart Disease Prevention: The Complete Cardiologist's Guide to Statins & Early Detection 700,000 Americans die from heart disease every year but most of these deaths are PREVENTABLE. In this groundbreaking episode, Dr. McConnell from Stanford reveals how to treat your heart like cancer: with early detection, proper treatment, and personalized prevention strategies that actually save lives.
Naveed Sattar joins host Catherine Glass to explore the complex relationship between diabetes and cardiovascular disease. From hyperglycaemia and inflammation to diabetes onset age and risk prediction, this episode examines the mechanisms and evidence shaping cardiometabolic care today. Timestamps: 0:55 – Diabetes to heart disease 4:35 – Age of onset 6:21 – Statins 09:01 – Epidemiological insights 12:29 – Improving risk prediction
Show Notes HOST Melody Hartzler | | Book Appointment AROUND THE TABLE Joel Kahn | | Visit Website In Today's Episode Preventive cardiologist Dr. Joel Kahn joins Melody Hartzler on this episode of Table Talk to break down how lifestyle changes, nutrition, and advanced diagnostic testing can protect your heart. Dr. Kahn shares his journey from traditional interventional cardiology to preventive care and explains how inflammation, diet, hormone changes, and personalized risk assessments can help identify cardiovascular issues before they become serious. Key Take Aways Heart disease prevention starts with understanding individual risk factors, including inflammation, family history, metabolic health, and lifestyle habits. Advanced testing such as coronary artery calcium scans, carotid ultrasounds, and inflammatory markers can provide a more complete picture of cardiovascular risk. Whole-food, plant-based nutrition remains one of the most powerful tools for preventing and even reversing heart disease. Lipoprotein(a) is an often-overlooked genetic risk factor that can significantly impact cardiovascular health, especially in women. Lifestyle changes—including nutrition, exercise, stress management, sleep, and weight management—should be the foundation of any heart health plan before considering more aggressive interventions. Topics Discussed 00:00 – Welcome to Table Talk Melody Hartzler introduces today's guest, preventive cardiologist Dr. Joel Kahn, and previews the discussion on heart disease prevention and functional medicine. 01:06 – Dr. Kahn's Journey to Preventive Cardiology Dr. Kahn shares how his experience in traditional cardiology led him to focus on preventing heart disease through lifestyle and nutrition. 03:00 – The Impact of Plant-Based Nutrition How nutrition transformed Dr. Kahn's approach to patient care and cardiovascular health. 04:15 – A Common Patient Scenario Discussing women approaching menopause and the cardiovascular changes that often emerge during this stage of life. 05:27 – Looking Beyond Standard Labs The importance of comprehensive cardiovascular assessments, lifestyle factors, and personalized risk evaluation. 06:00 – Understanding Inflammation and Heart Disease Key inflammatory markers and why inflammation plays a central role in cardiovascular health. 07:24 – Omega-3 Testing and Nutritional Strategies How omega-3 levels and targeted nutrition can support heart health and reduce risk. 07:41 – Measuring Arterial Health Using carotid ultrasounds and artery age assessments to detect cardiovascular issues early. 08:39 – Coronary Artery Calcium Scans Explained Who should consider a calcium scan and how it helps identify hidden heart disease risk. 09:51 – Interpreting Calcium Scores What different calcium scores mean and when intervention may be necessary. 11:37 – Advanced Cardiovascular Testing Exploring inflammatory markers, metabolic indicators, and additional tools for risk assessment. 12:38 – The Importance of Lipoprotein(a) Understanding this genetic risk factor and its role in cardiovascular disease. 14:00 – Supplements for Heart Health A discussion on red yeast rice, omega-3s, berberine, and other commonly used supplements. 15:31 – Niacin and Cholesterol Management When niacin may be helpful and how it fits into a cardiovascular prevention plan. 17:02 – Choosing Quality Supplements What to look for when selecting supplements and why quality matters. 19:00 – Red Yeast Rice vs. Statins Comparing natural and pharmaceutical approaches to cholesterol management. 20:00 – Statins, Side Effects, and CoQ10 Addressing common concerns and discussing strategies to support patients using statins. 24:00 – Is a Plant-Based Diet Necessary? Dr. Kahn shares his perspective on nutrition and individualized approaches to heart health. 26:00 – AGEs and Cooking Methods How advanced glycation end products affect cardiovascular health and practical ways to reduce exposure. 27:49 – Resources and Where to Find Dr. Kahn Dr. Kahn shares where listeners can learn more about his work and access additional resources. 28:18 – Final Thoughts and Closing Remarks Key takeaways from the conversation and a wrap-up of the episode. Resources Mentioned Table Talk Podcast — Resources & Links The PharmToTable Team – Functional Medicine Providers Therapies & Approaches Discussed: Preventive Cardiology Functional Medicine Plant-Based Nutrition Lifestyle Medicine Inflammation Reduction Hormone Replacement Therapy (HRT) Tests & Biomarkers Discussed: Coronary Artery Calcium (CAC) Scan Carotid Artery Ultrasound Lipoprotein(a) [Lp(a)] High-Sensitivity C-Reactive Protein (hs-CRP) Omega-3 Testing Supplements Discussed: Berberine Niacin (Vitamin B3) Endur-Acin® CoQ10 (Coenzyme Q10) Supplement Spotlight Vitamin D / K2 Liquid - 1 fl oz Purchase Today D3 5000 with K2 60 Softgels Purchase Today
Nutritionist Leyla Muedin discusses research showing simple strength tests—grip strength and a five-rep sit-to-stand chair test—predict longevity in older women. In a University at Buffalo study of over 5,000 women ages 63–99 followed for eight years, stronger grip and faster chair-stand times were linked to lower mortality; every additional 7 kg of grip strength corresponded to a 12% reduction in death risk, and faster chair-stands were also associated with improved survival, even after adjusting for activity, cardiovascular fitness, and inflammation. She emphasizes prioritizing muscle-strengthening alongside aerobic exercise and suggests accessible resistance options (weights, bodyweight moves, or household items) with professional guidance as needed. She then cites UK Biobank data linking long-term statin use to declines in grip strength and appendicular lean mass, urging discussion with physicians and added vigilance, especially for those also using GLP-1 drugs that may reduce protein intake and muscle mass.
“All good scientists are skeptics.” — Dr. Anthony Pearson Key Links The Skeptical Cardiologist on Substack is HERE American Heart Association 2026 Guidelines is HERE MESA CAC Database is HERE In this episode, I'm joined by Dr. Anthony Pearson, the cardiologist behind The Skeptical Cardiologist newsletter on Substack, for a practical conversation about what women over 50 need to know now about heart health. We talk about the new cholesterol guidelines, why personalized risk assessment matters, and why tests like CAC, Lp(a), and ApoB can reveal much more than a standard lipid panel alone. What You Will Learn: Why heart disease is still the number one killer of women The biggest blind spots women over 50 still have about heart risk What changed in the new cholesterol guidelines Why earlier detection and more personalized risk assessment matter Why CAC, Lp(a), and ApoB are getting more attention What those tests can reveal that a standard lipid panel may miss Why statins still matter, despite all the noise around them When non-statin options may make sense The role of inflammation in cardiovascular disease The lifestyle habits that still matter most for prevention A few key takeaways from this conversation You can feel healthy, exercise regularly, eat well, and still have hidden cardiovascular risk A standard cholesterol panel does not always tell the full story CAC, Lp(a), and ApoB can help create a more complete and individualized picture of risk High Lp(a) is inherited and is important to know about, even before a specific drug is widely available ApoB is a more precise marker of atherogenic particles and can add valuable information to routine testing Statins remain an important, well-studied first-line tool for many people Prevention works best when you start earlier, not after a cardiac event Cardio exercise, strength training, and maintaining a healthy body composition all matter Subscribe to AGE BETTER so you never miss an episode!
Episode 2805 - Vinnie Tortorich and Anna Vocino discuss a cholesterol conundrum regarding CAC scores, numbers, and how to naturally balance those numbers. https://vinnietortorich.com/2026/05/a-cholesterol-conundrum-episode-2805 PLEASE SUPPORT OUR SPONSORS Pure Vitamin Club Pure Coffee Club NSNG® Foods VILLA CAPPELLI EAT HAPPY KITCHEN YOU CAN WATCH THIS EPISODE ON YOUTUBE - @FitnessConfidential Podcast Vinnie's workout videos are available to purchase! Choose from a 2-day, 4-day, or 6-day workout–or buy all three at a discount! TO PURCHASE VINNIE'S WORKOUT VIDEOS, CLICK THIS LINK: https://vinnietortorich.com/workout A Cholesterol Conundrum Vinnie recently posted on social media about the Women's Health Initiative. (3:00) The problem with Google is that you can "Google yourself right," so you can always find confirmation bias. There is a growing awareness of what constitutes a "clean" product. (17:00) For example, Anna's spices do not have fillers, preservatives, or anti-caking agents. Vinnie shares a story about a recent consultation. (28:00) CAC scans (calcium score test) are a great guide to see if heart disease will be an issue for you. Repatha was recommended even though the patient's numbers were great, and his calcium score was zero. Consider exploring natural supplements and lifestyle changes to manage cholesterol. The Cholesterol Code movie by Dave Feldman provides good information on cholesterol levels and the benefits of a low-carb diet. Anna goes over some bloodwork numbers and wants to discuss with her doctor. (50:00) Remember that the number ranges given in the results are representative of the general population. (52:00) It is often recommended to take CoQ10 alongside a statin. Statins deplete CoQ10, which can lead to muscle damage. Anna's products are now linked to PureVitamin Club's website. Look under the "Food and Snacks" section so that you can purchase them there, too. (58:30) https://purevitaminclub.com/collections/food-and-snacks The NSNG® VIP GROUP IS NOW CLOSED AGAIN AS OF SUNDAY, MARCH 15TH Anna's next cookbook, Eat Happy Cocktail Hour, is filled with cocktails, mocktails, and appetizers and is available for pre-order right now. If you pre-order, you'll get bonus goodies! You can preorder from a wide variety of booksellers at https://eathappycocktailhour.com/ Save your receipt from wherever you preorder, you'll need it for your bonuses! Physical Release Date is October 2026 A New Sponsor Jaspr Air Scrubbers has a discount code, VINNIE, that gets you $200 off for a limited time. Jaspr offers a lifetime warranty. Go to Jaspr.co for more information or to purchase. (1:05:00) You can book a consultation with Vinnie to get guidance on your goals. https://vinnietortorich.com/phone-consultation-2/ More News Serena has added some of her clothing suggestions and beauty product suggestions to Vinnie's Amazon Recommended Products link. Self Care, Beauty, and Grooming Products that Actually Work! https://www.amazon.com/shop/vinnietortorich/list/3GPVU29UHHPMY?ref_=aipsflist Don't forget to check out Serena Scott Thomas on Days of Our Lives on the Peacock channel. "Dirty Keto" is available on Amazon! You can purchase or rent it here.https://amzn.to/4d9agj1 Please make sure to watch, rate, and review it! Eat Happy Italian, Anna's second cookbook, is available! You can go to https://eathappyitalian.com You can order it from Vinnie's Book Club. https://amzn.to/3ucIXm Anna's recipes are in her cookbooks, on her website, and on Substack —they will spice up your day! https://annavocino.substack.com/ PURCHASE DIRTY KETO (2024) The documentary launched in August 2024! Order it TODAY! This is Vinnie's fourth documentary in just over five years. Visit my new Documentaries HQ to find my films everywhere: https://vinnietortorich.com/documentaries Then, please share my fact-based, health-focused documentary series with your friends and family. Additionally, the more views it receives, the better it ranks, so please watch it again with a new friend! REVIEWS: Please submit your REVIEW after you watch my films. Your positive REVIEW does matter! PURCHASE BEYOND IMPOSSIBLE (2022) Visit my new Documentaries HQ to find my films everywhere: https://vinnietortorich.com/documentaries FAT: A DOCUMENTARY 2 (2021) Visit my new Documentaries HQ to find my films everywhere: https://vinnietortorich.com/documentaries FAT: A DOCUMENTARY (2019) Visit my new Documentaries HQ to find my films everywhere: https://vinnietortorich.com/documentaries
Adam talks with American journalist Patrick Radden Keefe about his book London Falling: A Mysterious Death in a Gilded City and a Family's Search for Truth, the challenges presented by parenting adolescents, the seductive power of movies like The Wolf Of Wall Street and Patrick's own efforts to resist the glamorising effect of TV and film during production of the TV adaptation of his book about the Troubles in Northern Ireland, Say Nothing, and Adam's own ludicrous taste of the criminal life in his early adolescence. There's also chat about why David Byrne's live show was the best live music show Adam has ever seen and whether it's OK to stand up at a seated music show.Conversation recorded face-to-face in Bath on 7 May, 2026LONDON FALLING by Patrick Radden Keefe - 2026 (Waterstones)CLARIFICATION RE. STATINS vs GLP-1sResponding to Adam's comments about statins at the end of the conversation with Patrick, this was sent in by Dr Mit Shah, MBBS BSc (Hons) PhD, Consultant Cardiologist in Preventive Cardiology, Harefield Hospital:I'm a consultant cardiologist specialising in lipid disorders and preventive cardiology. While both GLP-1 drugs and statins can reduce cardiovascular risk, they work through very different mechanisms and treat different underlying problems. Statins are specifically used to lower LDL cholesterol, whereas GLP-1 drugs mainly work through the blood glucose and weight-loss pathway, with only modest effects on cholesterol.Statins have become somewhat unfairly maligned through widespread misinformation and exaggerated claims about side effects, despite very strong clinical evidence for benefit. In fact, researchers have even performed randomised trials demonstrating a significant “nocebo effect”, where patients experience expected side effects even when taking placebo tablets due to their preconceived expectations and worries. Daily, I see patients with severe (sometimes genetic) cholesterol disorders who have a critical need for statin therapy, but who are understandably hesitant because of what they've heard online. I worry that the idea that GLP-1s could simply replace statins may unintentionally add to that confusion.SUBMIT QUESTIONS FOR Q&A EPISODE: Adambuxtonpodcast@gmail.comThanks to Diggory Waite and Claire Broughton at Hattrick and Séamus Murphy Mitchell for production support.Podcast illustration by Helen GreenSPONSOR: SAILY
Join the Conversation at 303-477-5600 or text to 307-200-8222 Monday - Friday from 3 pm - 6 pm MT. https://RushToReason.com HOUR 1 Health Fears, Government Distrust, And The Battle Over Who Controls Your Health. Hour 1 of Rush To Reason examines America's growing distrust of its healthcare institutions, government agencies, and pharmaceutical systems. John Rush, Dr. Kelly Victory, and Steve House open with Ebola fears, media panic cycles, and the possibility of public fear campaigns driving headlines over science. The conversation quickly deepens: Are Americans being told the full truth about vaccines, pharmaceuticals, food additives, and public health policies? The hour explores controversial topics, including tick-borne illnesses, alpha-gal syndrome, FDA oversight, prescription drug pricing, statins, vaccine testing, and political influence within health agencies. Dr. Kelly questions the conventional thinking on cholesterol, statin use and modern medicine's dependence on pharmaceuticals, while Steve House questions whether Americans can still trust the systems designed to protect them. The conversation also examines Mark Cuban's support of lower prescription drug costs and whether the future of healthcare depends more on personal responsibility than government intervention. By the end of the hour, one unsettling question demands an answer: In an era of confusion and competing interests, who can you trust with your health? Dr. Kelly Victory - https://www.rushtoreason.com/dr-kelly-victory-2/ HOUR 2 Artificial Intelligence, Family Values, And The Cultural Battles Reshaping America. Hour 2 of Rush To Reason is a rollercoaster of hot-button issues and spirited debate you won't want to miss. The stakes are high as John Rush kicks things off with attorney and law enforcement advocate Lance LaRusso, diving into the unsettling world of AI-generated deepfakes and the chaos they could unleash on our justice system. Can we still trust what we see and hear? As technology blurs the line between truth and fiction, the hour exposes the cracks forming in media credibility, public confidence, and the very foundation of justice. But that's just the beginning. The tension escalates with shocking NASCAR news; rumors swirl about the reported death of Kyle Busch, before the show dives headfirst into the high-stakes world of political strategy, campaign chaos, and the influence of celebrities on public opinion. Katie Faust brings the heat as she and John tackle the most controversial questions about family, gender ideology, and the forces reshaping America's core values. All this, plus a spirited takedown of Marxist narratives, climate change debates, and a lighthearted close with automotive tips and Drive Radio success stories. This hour is packed with drama, insight, and moments that will have you questioning everything you thought you knew about where our country is headed. Timestamps 1:12 — Lance LaRusso — https://bluelinelawyer.com/ 25:53 — Katie Faust — https://thembeforeus.com/
Highlights from Dr. Hoffman's Scandinavian tripShould I eliminate the nightshade family of foods from my diet?My friend has been experiencing acid reflux since using a reverse osmosis water filtration system
On this vintage episode of Vitality Radio, Jared takes a hard look at the cholesterol hypothesis and why it has failed to deliver true solutions for heart health. Instead of focusing on lowering cholesterol—a vital compound for hormones, brain function, and cellular integrity—he highlights the often-overlooked root cause: stiff, aging arteries. You'll learn how the blood vessels lose flexibility with age, stress, toxins, poor diet, and inactivity, and why this breakdown leads to high blood pressure and drives cardiovascular risk far more than cholesterol numbers alone. Jared explains the role of nitric oxide in reversing arterial aging and how natural boosters like beets, leafy greens, and amino acids support healthy nitric oxide production. This episode is about shifting the conversation: instead of suppressing what the body needs, learn how to encourage its own built-in repair and resilience mechanisms.Products:N.O. Cardio BoostVital D3/K2Ultimate Vitality MultiNutraBio Beet Root PowderSolaray Beet Root CapsulesNutraBio L-Citrulline PowderBlack Market Labs L-Citrulline PowderJust Ingredients Pre-Workout Visit the podcast website here: VitalityRadio.comYou can follow @vitalitynutritionbountiful and @vitalityradio on Instagram, or Vitality Radio and Vitality Nutrition on Facebook. Join us also in the Vitality Radio Podcast Listener Community on Facebook. Shop the products that Jared mentions at vitalitynutrition.com. Let us know your thoughts about this episode using the hashtag #vitalityradio and please rate and review us on Apple Podcasts. Thank you!Just a reminder that this podcast is for educational purposes only. The FDA has not evaluated the podcast. The information is not intended to diagnose, treat, cure, or prevent any disease. The advice given is not intended to replace the advice of your medical professional.
Broadcast from KSQD, Santa Cruz on 5-14-2026: An emailer from Switzerland follows up on the case of neurological symptoms, warning about the fox tapeworm Echinococcus multilocularis from unwashed garden vegetables and tick-borne encephalitis requiring the FSME vaccine available in Europe. Dr. Dawn adds that cysticercosis from undercooked pork leaves calcified brain lesions detectable on CT scans. Dr. Dawn covers the Andes hantavirus outbreak that sickened at least eleven people on a cruise ship, with the virus spreading person-to-person unlike other hantaviruses. She explains that Andes virus grows to unusually high levels in blood and resists antimicrobial compounds in human saliva, with super-spreaders driving transmission chains. British paratroopers had to parachute medical supplies to an infected passenger on remote Tristan da Cunha island. Dr. Dawn reviews brain health supplements with UCLA longevity expert Gary Small. Both recommend curcumin (500-1,000mg) for anti-inflammatory effects and CoQ10 for statin users. She endorses multivitamins and high-quality fish oil but considers creatine, phosphatidylserine, and nicotinamide riboside insufficiently proven for cognitive enhancement. A caller asks about supplements and testosterone for a 77-year-old. Dr. Dawn recommends topical testosterone (patches, creams, gels) over injections to avoid testicular shrinkage and elevated sex hormone-binding globulin. She emphasizes protein intake matching one's age in grams, branched-chain amino acids during exercise, and warns against fasted training after age 65. An emailer shares news that PCOS is being renamed to polyendocrine metabolic ovarian syndrome (PMOS) because many patients lack ovarian cysts, and genetic males can also have the condition. Dr. Dawn explains it's fundamentally an endocrine and metabolic disorder involving insulin resistance, elevated testosterone, and DHEA dysregulation. A study found that infrasound—low-frequency sound below human hearing range—elevated cortisol and worsened mood in subjects who didn't know and couldn't detect it was playing. Old buildings generate infrasound through aging boilers, ventilation ducts, and metal pipes, potentially explaining why, beyond autosuggestion, that old "haunted" houses feel spooky.
Send us Fan MailWhat if the symptoms women are told to “just live with” are actually signs of hormone imbalance?In this episode of Never Been Sicker, Michael Rubino sits down with Dr. Melissa Miskell to discuss hormone health, aging, inflammation, thyroid issues, brain fog, fatigue, menopause, and why so many women are being dismissed instead of properly tested. The conversation also dives into statins, cholesterol, processed food, environmental toxins, and how modern lifestyles may be contributing to chronic illness and hormone disruption.If you've been struggling with fatigue, brain fog, mood swings, poor sleep, low libido, hot flashes, or simply “not feeling like yourself,” this episode may completely change the way you think about hormones and healthy aging.Timestamps00:00 Intro00:19 Why hormones matter01:24 When hormones start changing02:20 Symptoms women experience03:01 Why women get dismissed04:32 Why doctors avoid hormones05:07 Signs of hormone imbalance05:59 Common symptoms women ignore07:22 What hormone therapy looks like08:29 Improvements women notice first09:40 How long treatment lasts10:48 Hormones, thyroid & lifestyle11:17 Hormones and heart health12:32 Estrogen and dementia13:06 Osteoporosis explained14:12 Inflammation and brain health15:29 Thyroid problems and testing18:37 Low vs high hormones20:48 The biggest hormone myth21:16 Does estrogen cause breast cancer?22:20 The Women's Health Initiative controversy24:19 Hormone replacement controversies26:24 Statins and hormone depletion28:47 Cholesterol, sugar & heart disease31:00 Why we've never been sicker33:11 Why hormones are overlooked34:31 Hormone symptoms in men34:52 You don't have to feel this way35:23 Where to find Dr. Melissa-----------------------------------------------------------------------------------------------Follow Dr. Melissa Miskell
Hour 3 of the Bob Rose Show, on a new health study showing the direct benefit of egg consumption reducing Alzheimer development. Changing studies, the impact of big pharma, and new views on eggs. Plus, the latest on a potential deal forming to end the Iran war, and all of Friday morning's biggest news stories for 5-8-26
For decades, a tight carotid stenosis felt like a ticking time bomb — a plaque waiting to throw an embolus and cause the next stroke. We were taught that severe narrowing meant surgery, and trials like ACAS and ACST-1 seemed to prove it. But medicine has changed. Statins, antiplatelets, tighter blood pressure control, even PCSK9 and GLP-1 therapies have quietly slashed stroke risk, and now newer data from CREST-2 suggest that for many asymptomatic patients, the knife — or the stent — may not add much at all. So if modern medical therapy works better than ever… who actually benefits from intervention anymore? Today, we unpack the evidence, the controversies, and how to counsel the patient who feels perfectly fine but has high-grade stenosis.Hosts: Carolyn Judge, Andrew Huang, Luciano Delbono, Frank Davis, Robert BeaulieuInstitution: University of Michigan, Department of Surgery, Section of Vascular SurgeryLearning objectives: Describe how modern intensive medical therapy has transformed the natural history of asymptomatic carotid stenosis and explain why contemporary patients experience substantially lower annual stroke risk than those in earlier eras. Interpret and compare the results of landmark trials—including ACAS, ACST-1, and CREST-2—to assess the relative benefits of medical therapy, endarterectomy, and stenting. Apply current evidence and guideline recommendations to patient care by selecting which asymptomatic patients are most likely to benefit from carotid revascularization versus optimized medical therapy alone. References:SVS Guidelines:Brook, R. D., et al. (2022). Society for Vascular Surgery clinical practice guidelines for management of extracranial carotid artery disease. Journal of Vascular Surgery, 75(1), e1–e67. https://doi.org/10.1016/j.jvs.2021.09.031CREST (1)Brott, T. G., Hobson, R. W., Howard, G., et al. (2010). Stenting versus endarterectomy for treatment of carotid-artery stenosis. New England Journal of Medicine, 363(1), 11–23. https://doi.org/10.1056/NEJMoa0912321CREST-2Brott, T. G., Howard, G., Fong, P., et al. (2024). Randomized trial of carotid artery stenting or carotid endarterectomy vs best medical therapy for asymptomatic carotid stenosis: CREST-2 results. [Manuscript in preparation]. ClinicalTrials.gov Identifier: NCT02089217. Retrieved from https://clinicaltrials.gov/ct2/show/NCT02089217ACST-1Halliday, A., Mansfield, A., Marro, J., et al. (2004). Randomised trial of carotid artery surgery for asymptomatic stenosis. Lancet, 363(9420), 1491–1502. https://doi.org/10.1016/S0140-6736(04)16153-1ACST-2Halliday, A., Bulbulia, R., Bonati, L. H., et al. (2021). Carotid artery stenting versus carotid endarterectomy in patients with asymptomatic carotid stenosis (ACST-2): A randomised trial. Lancet, 398(10291), 1065–1073. https://doi.org/10.1016/S0140-6736(21)01980-1ACASExecutive Committee for the Asymptomatic Carotid Atherosclerosis Study. (1995). Endarterectomy for asymptomatic carotid stenosis. JAMA, 273(18), 1421–1428. https://doi.org/10.1001/jama.1995.03520420033036Sponsor URL: https://www.goremedical.com/Please visit https://behindtheknife.org to access other high-yield surgical education podcasts, videos and more. If you liked this episode, check out our recent episodes here: https://behindtheknife.org/listenBehind the Knife Premium: https://behindtheknife.org/premiumOral Board Review: https://behindtheknife.org/oral-boardOral Board Simulator: https://behindtheknife.org/oral-board/simulatorGeneral Surgery Oral Board Review Course: https://behindtheknife.org/premium/general-surgery-oral-board-reviewTrauma Surgery Video Atlas: https://behindtheknife.org/premium/trauma-surgery-video-atlasDominate Surgery: A High-Yield Guide to Your Surgery Clerkship: https://behindtheknife.org/premium/dominate-surgery-a-high-yield-guide-to-your-surgery-clerkshipDominate Surgery for APPs: A High-Yield Guide to Your Surgery Rotation: https://behindtheknife.org/premium/dominate-surgery-for-apps-a-high-yield-guide-to-your-surgery-rotationVascular Surgery Oral Board Review Course: https://behindtheknife.org/premium/vascular-surgery-oral-board-audio-reviewColorectal Surgery Oral Board Review Course: https://behindtheknife.org/premium/colorectal-surgery-oral-board-audio-reviewSurgical Oncology Oral Board Review Course: https://behindtheknife.org/premium/surgical-oncology-oral-board-audio-reviewCardiothoracic Oral Board Review Course: https://behindtheknife.org/premium/cardiothoracic-surgery-oral-board-audio-reviewDownload our App:Apple App Store: https://apps.apple.com/us/app/behind-the-knife/id1672420049Android/Google Play: https://play.google.com/store/apps/details?id=com.btk.app&hl=en_US
A case study where a second opinion is necessaryWhat are your thoughts on the recent news implicating niacin in cardiovascular disease?
Send Zorba a message!Zorba digs into how harmful are the chemicals that make our lawns weed-free and impossibly green. He helps out a caller who wants to politely switch doctors, and he helps a listener who has statin questions. Zorba weighs in on tart cherry extract, we hear a mom joke, and Karl talks about the shock jock radio DJs from his childhood.Support the showProduction, edit, and music by Karl ChristensonSend your question to Dr. Zorba (he loves to help!):Phone: 608-492-9292 (call anytime)Email: askdoctorzorba@gmail.comWeb: www.doctorzorba.orgStay well!
Send Zorba a message!Zorba digs into how harmful are the chemicals that make our lawns weed-free and impossibly green. He helps out a caller who wants to politely switch doctors, and he helps a listener who has statin questions. Zorba weighs in on tart cherry extract, we hear a mom joke, and Karl talks about the shock jock radio DJs from his childhood.Support the showProduction, edit, and music by Karl ChristensonSend your question to Dr. Zorba (he loves to help!):Phone: 608-492-9292 (call anytime)Email: askdoctorzorba@gmail.comWeb: www.doctorzorba.orgStay well!
Why are humans so sensitive to the smell of rain? Do statins cause dementia? What is the storage capacity of the human brain? How can I remember all the information I study? Do scientists believe in God? How do vultures find their prey? How can I stop or reverse grey hair? What does a cataract operation involve? What is diastolic blood pressure? Are MRI scans harmful to toddlers? And is Dr Chris worried that AI will replace him?! Dr Chris Smith and Clarence Ford have the answers... Like this podcast? Please help us by supporting the Naked Scientists
Why are humans so sensitive to the smell of rain? Do statins cause dementia? What is the storage capacity of the human brain? How can I remember all the information I study? Do scientists believe in God? How do vultures find their prey? How can I stop or reverse grey hair? What does a cataract operation involve? What is diastolic blood pressure? Are MRI scans harmful to toddlers? And is Dr Chris worried that AI will replace him?! Dr Chris Smith and Clarence Ford have the answers... Like this podcast? Please help us by supporting the Naked Scientists
Which is the safest and most effective?
Send Zorba a message!Zorba talks about "Statin Hysteria" and people's reluctancy with taking them. He helps out a caller with questions about Astepro nasal spray, and he helps a listener who has questions about Vitamin D and HRT. Zorba shares his daughter's favorite Gazpacho recipe, he gives advice about taking THC gummies for sleep, and we hear a mom joke that is so good it needs to be explained.Support the showProduction, edit, and music by Karl ChristensonSend your question to Dr. Zorba (he loves to help!):Phone: 608-492-9292 (call anytime)Email: askdoctorzorba@gmail.comWeb: www.doctorzorba.orgStay well!
Send Zorba a message!Zorba talks about "Statin Hysteria" and people's reluctancy with taking them. He helps out a caller with questions about Astepro nasal spray, and he helps a listener who has questions about Vitamin D and HRT. Zorba shares his daughter's favorite Gazpacho recipe, he gives advice about taking THC gummies for sleep, and we hear a mom joke that is so good it needs to be explained.Support the showProduction, edit, and music by Karl ChristensonSend your question to Dr. Zorba (he loves to help!):Phone: 608-492-9292 (call anytime)Email: askdoctorzorba@gmail.comWeb: www.doctorzorba.orgStay well!
Leveling Up: Creating Everything From Nothing with Natalie Jill
What if the cholesterol medication your doctor insists could save your life is actually increasing your risk of the very disease it's supposed to prevent? A board-certified cardiothoracic surgeon who has personally performed over 3,000 open-heart surgeries joins us this week with a message he says most cardiologists will not say out loud: the majority of his patients should never have ended up on his table. Dr. Philip Ovadia lost nearly 100 pounds while operating on other people's hearts, reversed his own prediabetes, and spent the last decade asking a question his colleagues are not comfortable with: what is actually causing heart disease? This episode goes deep. You will learn why your LDL number tells you almost nothing meaningful without particle size testing, why statins lower the wrong kind of cholesterol, and why insulin resistance is a far bigger driver of heart events than anything showing up on a standard lipid panel. Dr. Ovadia also walks through the most important heart tests most women have never had, including the coronary artery calcium scan he calls "the mammogram for your heart," and gives his take on every medication in the conversation from statins to Zetia to Repatha. If you have ever left a cardiology appointment more confused and scared than when you walked in, this one is for you. Learn More About Dr. Philip Ovadia Instagram ➜ https://www.instagram.com/ifixhearts Website ➜ http://ifixhearts.com/ Preorder Stay Off My Kitchen Table ➜ https://stayoffmykitchentable.com/ Thank you to our show sponsors: TIMELINE: Timeline is offering 20% off your order of Mitopure! Go to https://timeline.com/NATALIEJILL Free Gifts for being a listener of Midlife Conversations! Mastering the Midlife Midsection Guide: https://theflatbellyguide.com/ Age Optimizing and Supplement Guide: https://ageoptimizer.com Connect with me on social media! Instagram: www.Instagram.com/Nataliejllfit Facebook: www.Facebook.com/Nataliejillfit For advertising inquiries: https://www.category3.ca/ Disclaimer: Information provided in the Midlife Conversations podcast is for informational purposes only. This information is NOT intended as a substitute for the advice provided by your physician or other healthcare professional. Do not use the information provided in this podcast for diagnosing or treating a health problem or disease, or prescribing medication or other treatment. Always speak with your physician or other healthcare professional before making any changes to your current regimen. Information provided in this podcast and the use of any products or services related to this podcast does not create a client-patient relationship between you and the host of Midlife Conversations or you and any doctor or provider interviewed and featured on this show. Information and statements may have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent ANY disease. Advertising Disclosure: Some episodes of Midlife Conversations may be sponsored by products or services discussed during the show. The host may receive compensation for such advertisements or if you purchase products through affiliate links. Opinions expressed about products or services are those of the host and/or guests and do not necessarily reflect the views of any sponsor. Sponsorship does not imply endorsement of any product or service by healthcare professionals featured on this podcast.
AI slop brought to you by Gemini 3 (flash - thinking) and it thinks I am Jack because of the transcript. Whatever. Enjoy the show! There's a TCRP coming soon I promise! Episode SummaryIn episode 154 of The Two Jacks, Jack the Insider (Joel Hill) and Hong Kong Jack dive deep into the complexities of Australian identity. From the controversial booing of the "Welcome to Country" at Anzac Day ceremonies to the historical economic hangover of the White Australia Policy, the duo explores what it actually means to hold "Australian values". They also tackle the latest in UK political scandals, the AFL's handling of player mental health, and why the Scottish football league might finally see a break in its 40-year duopoly. Show Notes & Timestamps00:00:25 – Hong Kong's Economic MorassHong Kong Jack reports on the quiet but steady economic decline in the territory as the Iran war impacts fuel and food costs. With almost no local agriculture, Hong Kong citizens are feeling the pinch as airlines cut back on flights and shipping costs rise. A look ahead to next week's discussion on global food security and the impact of fertilizer shortages on the world's "food bowls". 00:04:14 – Statins and Political Party NamesAddressing listener feedback regarding the use of statins and the regulation of supplements versus prescribed drugs. The hunt for a new right-wing political party name: Why all the "good ones" are already taken or deregistered. 00:06:25 – The Anzac Day "Welcome to Country" ControversyDiscussion on the organised campaign to boo "Welcome to Country" ceremonies during Anzac Day. A debate on the ubiquity of these acknowledgments in corporate and social settings versus their place in national commemorations. Jack the Insider addresses the xenophobic undercurrents appearing in modern political discourse. 00:16:00 – Deep Dive: Australian Values & MigrationThe Values Test: Hong Kong Jack shares his experience taking the Australian values test, describing it as "bizarre" and "a waste of time". Electoral Fairness: Jack the Insider argues that Australia's true values are embedded in its robust, independent electoral system and compulsory voting. Historical Hangover: A look at George Megalogenes' theories on how the White Australia Policy consigned Australia to decades of cultural isolation and economic underperformance. Integration Success: Lessons from the Snowy River Scheme and how Australia's "integrative multiculturalism" differs from the failed European models. 01:07:27 – UK Politics: Process & ScandalThe pair discusses Keir Starmer's obsession with "process" and the controversial potential appointment of Peter Mandelson as UK Ambassador to the US. 01:09:47 – Footy & SportElijah Hollands: A sensitive discussion on the mental health episode experienced by the Carlton player during the Collingwood game and the subsequent media fallout. Professional Umpiring: Why the AFL needs to move away from "weekend warrior" umpires and towards a fully professional panel to handle increasingly complex rules. Global Scores: The EPL title race heats up between Arsenal and Man City, while Hearts looks to break the Celtic/Rangers duopoly in Scotland. 01:33:42 – Closing Thoughts: Germany's 2039 GoalA brief look at Germany's stated aim to have Europe's strongest conventional fighting force by 2039—a date that raises more than a few historical eyebrows. Contact the ShowEmail: conditionalreleaseprogram@gmail.com X (formerly Twitter): Reach out to Jack the Insider or find Hong Kong Jack for tips on the HK racing scene. Substack: Check out Jack's latest writings.
The Real Truth About Health Free 17 Day Live Online Conference Podcast
Stents, statins, and surgeries don't cure the problem—food does. Hear why lifestyle change is the true intervention. #StatinMyths #HeartFix #LifestyleMedicine #HealthTalks
Why aren't they prescribed for everyone?
The Real Truth About Health Free 17 Day Live Online Conference Podcast
Bone Health Indicators and Muscle Mass; Sleep's Role in Memory and Hormone Regulation; Sleep and Amyloid Clearance; Alcohol and Caffeine Disrupt Sleep; High-Protein Diets Can Hinder Serotonin and Sleep; Nighttime Bathroom Trips and Sleep Disruption; Sleep Medications and Cognitive Risk; Statins and Antidepressants Can Mimic Dementia; Purpose and Depression in Older Adults; Menopause as Natural, Not a Disease; Menopause Experiences Across Cultures; Hormone Replacement Therapy and Breast Cancer Risk #HealthyAging #Longevity #BrainHealth #HealthTalks
A ketogenic diet put his ulcerative colitis into complete remission — off all medications, confirmed on colonoscopy. Dr. Nick Norwitz (PhD Oxford, MD Harvard) explains why evidence-based care isn't always optimal care, how keto rewires the gut and brain, and why GLP-1 drugs should catalyze lifestyle change, not replace it.CHAPTERS:0:00 - The most remarkable thing about my story is it's not unique1:14 - Welcome Nick Norwitz — Oxford PhD, Harvard MD2:02 - Ulcerative colitis, desperation, and keto remission5:34 - What medical school doesn't teach8:05 - Why evidence-based care ≠ optimal care15:53 - The carnivore-ketogenic IBD case series (10 patients)18:50 - Fiber elimination in pediatric Crohn's — 60–85% remission20:00 - Keto for depression: Ohio State trial — 69–71% reduction23:49 - Seed oils: the nuanced truth29:32 - Ketones and neurodegenerative disease32:52 - Autophagy, lateral habenula, and depression36:16 - Sonnenburg 2021: fermented foods beat fiber for inflammation37:20 - GLP-1 agonists: good tool, poor deployment43:29 - Statins slash GLP-1 by ~50% (Cell Metabolism, 2024)48:57 - ClosingREFERENCES:Carnivore-Keto for IBD (Norwitz et al., Frontiers, 2024): PMC11409203Keto for Depression (Ohio State, 2025): PMC12420795Fermented Foods vs Fiber (Sonnenburg, Cell, 2021): Stanford NewsStatins Slash GLP-1 (Cell Metabolism, 2024): pubmed/38325336Autophagy + Depression (Nature, 2025): NatureGUEST: Nick Norwitz, PhD MDHOST: Dr. Robert Lufkin MD | robertlufkinmd.com⭐ Enjoying the show? Please leave a 5-star review on Apple Podcasts — it takes 30 seconds and helps more people discover the science of health and longevity. Thank you!New episodes every Tuesday & Thursday. Subscribe so you don't miss one.Continue this conversation on Substack: https://robertlufkinmd.substack.comLies I Taught In Medical School — Free sample chapter: https://www.robertlufkinmd.com/lies/Web: https://www.robertlufkinmd.comYouTube: https://www.youtube.com/robertlufkinmdX: https://x.com/robertlufkinmdInstagram: https://www.instagram.com/robertlufkinmd/TikTok: https://www.tiktok.com/@robertlufkinLinkedIn: https://www.linkedin.com/in/robertlufkinmd/
I'm confused by information presented on diets containing meat as being dangerous. Could you shed some light?Assisted living models that would be of benefit to older adults
This weeks AI slop is being served to you by Google Gemini. Forgot to turn on thinking, so this is the 'fast' slop. Which may or may not be lesser quality than the other option which I may or may not be paying for. The robot still thinks Jack is Joel or whatever but otherwise the shownotes are objectively true and perfect and if you say otherwise a drone will land in your lap before you can say 'skynet is sentient' Enjoy! Episode OverviewIn this packed episode, the Jacks navigate the fallout of the Iran War on global energy and local prices , dive into the administrative "stuff-ups" threatening to flip a South Australian election seat , and analyze the Coalition's new, "nebulous" immigration policy. Plus, a deep dive into the "Human Fuel" craze, the fall of a California gubernatorial frontrunner, and why you should never, ever ask an Australian sports editor who Ron Barassi is.Timestamps(Note: Timestamps include a 25-second offset for theme music)00:00:25 – Intro & The Iran War Context: Greetings from Hong Kong, where transport costs are biting and lamb chops have their own plane seats.00:02:18 – The Narunga Recount: A 58-vote margin, 77 unopened ballots, and an administrative "stuff-up" in South Australia.00:04:15 – Election Lore: Remembering the Victorian seat decided by a hat and the missing WA Senate ballots.00:06:11 – The Gold Standard: Why paper, pencils, and scrutineers keep the "fix" out of Australian federal elections.00:11:25 – Farrah By-Election: One Nation surging to 40% in the polls—can an Independent bridge the gap on preferences?.00:17:15 – Geelong Refinery Blaze: Equipment failure at Corio disrupts 10% of the nation's fuel supply.00:18:52 – Immigration & "Australian Values": The Coalition's phone-checking policy and the shifting demographics of India vs. England-born Australians.00:25:13 – The Visa Spiral: Why dealing with the newest protection visa applications first might actually kill the backlog.00:33:59 – The Net Zero Reality Check: Surging global energy demand sees fossil fuels and renewables hitting record consumption simultaneously.00:43:04 – Geopolitics & Markets: The S&P 500 hits record levels on "vibe-based" hopes for an Iran War resolution.00:49:50 – Bowen's "Grab Bag of Nonsense": Fuel excises and the bizarre government advice to "take your roof racks off".00:55:50 – Resume Embellishment: From fake soccer stars to the fall of an LGBT activist with an "AI-generated" face.01:05:27 – The Fall of Eric Swalwell: A California frontrunner disappears under the bus in record time.01:13:19 – The Orban Era Ends: Peter Magyar's TISA party takes Hungary, but the EU migration pact is still a "no".01:16:14 – Huel, Statins, and Anti-Vaxxers: Why the middle class is trading doctors for supplements and "essence of blackberry".01:25:01 – Sport: The Zach Butters tribunal farce, junior AFL's struggle in Western Sydney, and Gout Gout's record-breaking straight.Social Media Blurb (Facebook)
Millions of people leave their doctor's office with "normal" bloodwork — and still feel terrible. Fatigued, foggy, anxious, in pain. If that's you, Dr. Terri has a message: your labs aren't lying, but the reference ranges might be. In this solo episode, Dr. Terri breaks down exactly why the standard of care is failing patients, how clinical reference ranges have quietly shifted to accommodate a sicker and sicker population, and what comprehensive, preventative testing actually looks like — including a full list of labs you can bring to your next appointment. If you've been dismissed, minimized, or told to just get older gracefully — this one is for you. Labs Dr. Terri recommends asking your provider for: Thyroid TSH (Thyroid Stimulating Hormone) Free T3 Free T4 Reverse T3 TPO Antibodies (Thyroid Peroxidase) Hormones Testosterone (men and women) Estrogen DHEA FSH (Follicle Stimulating Hormone) LH (Luteinizing Hormone) Progesterone (especially if dealing with infertility or irregular cycles) 4–5 Point Salivary Cortisol Panel Metabolic Fasting Insulin (optimal: 9–12) Hemoglobin A1C Full Lipid Panel with particle size and ApoLipoprotein analysis (NMR panel or Cleveland Clinic panel recommended) CRP (C-Reactive Protein) — inflammatory marker Nutrients Vitamin D (optimal: 60–100) Vitamin B12 (optimal: 800+) Ferritin / Iron stores (optimal: 70–150) RBC Magnesium (red blood cell level — not serum) Omega-3 Index (omega-3 to omega-6 ratio) Gut GI Map Test Your symptoms are real. Your body is sending a signal. Dr. Terri gives you the roadmap to finally get the answers you deserve. For a deeper dive into Thyroid, check out this episode with Dr. Johnny Peet -https://www.youtube.com/watch?v=T1ITw0lMwwk Episode Chapters: 00:00 — Introduction 07:01 — Why Patients Are Told "Everything Is Normal" 10:35 — Why "Normal" and Optimal Are Not the Same Thing 13:38 — The Tests Your Doctor Should Be Running (But Probably Isn't) 22:01 — Cholesterol, Statins, and the Metabolic Markers That Actually Matter 26:11 — Nutrient Deficiencies, Gut Health & Sleep as Root Cause Drivers 30:31 — Practical Next Steps: Labs to Request, Providers to Seek -- The Dr. Terri Show is presented by Evexias Health Solutions. For more, visit: https://www.evexias.com ---------------------------------------------------------------- Connect with Dr. Terri DeNeui, DNP:
Dr. Hoffman continues his conversation with Dr. Jeffrey Bland, Founder and President of the Personalized Lifestyle Medicine Institute and President of Big Bold Health.
Dr. Jeffrey Bland, Founder and President of the Personalized Lifestyle Medicine Institute and President of Big Bold Health, is described as the “godfather of functional medicine.” He details the origins of functional medicine as a systems-biology, root-cause approach emphasizing diet, lifestyle, and supplements alongside conventional allopathic care, especially for chronic disease. Bland contrasts medication “number needed to treat” examples (statins and TNF-alpha blockers) with personalized lifestyle interventions, noting adherence challenges. He discusses GLP-1 weight-loss drugs as a major pharmacologic advance but raises concerns about long-term effects, discontinuation rates, side effects, and inadequate nutrition if food intake drops. Bland describes research on bitter compounds and gut “taste” receptors influencing GLP-1 and related hormones, links to Blue Zone diets, and introduces Big Bold Health's Himalayan Tartary Buckwheat and minimally processed, sustainably sourced fish oil products, the Omega-3 index, and targeted formulations with lutein/astaxanthin, plus ongoing clinical trials on immune aging and gene expression.
In this episode, Beth and I reflect on our recent Nevis to St Kitts swim, a brilliant open water adventure that reminded us what it really means to be Battle Ready. We talk about the event itself, the experience of swimming across open water in a stunning setting, and what we learned from it. Then we shift gears into a more personal topic. I share why, after years of resisting it, I've decided to start taking statins. It's not medical advice, but an honest conversation about health, ageing, and the difference between being fit and being truly healthy for the long term. Key Points The Nevis to St Kitts swim experience A 2.5-mile open water swim in warm Caribbean waters, inclusive, well organised, and accessible to a wide range of swimmers. Adventure vs preparation You don't need perfect preparation to take on meaningful challenges, but the experience highlighted where more specific endurance work would help. Battle Ready in action Being consistently fit allowed us to step into an event like this with confidence and enjoy the experience. Fit doesn't equal healthy You can look strong, perform well, and still have underlying health risks that aren't visible on the surface. Why I changed my stance on statins After years of resisting medication, a combination of medical advice, real-life examples, and perspective on long-term risk led me to rethink my position. 3 Takeaways Train for life, not just events Being Battle Ready means you can say yes to opportunities without needing perfect preparation. Don't confuse fitness with health Performance metrics don't tell the full story. What's happening “under the hood” matters just as much. Play the long game Whether it's training, lifestyle, or medical decisions, the goal is to keep doing what you love for decades, not just today. Killer Quote “Just because you're fit, it doesn't mean you're invincible.” Resources Find out more about the Nevis - St Kitts Cross Channel Swim Nick Parkes podcast - The Day My heart Stopped Mid-Race Want help building durable training? Inside the SWAT Inner Circle you'll find structured training plans, strength programmes and regular coaching insights designed to help endurance athletes train consistently without breaking down. £30 per month. CLICK HERE TO START YOUR MISSION Connect with me HERE: https://linktr.ee/simonward You can find links for the following channels - Website, Facebook, podcast, Instagram, YouTube Email: Simon@thetriathloncoach.com Sign up for Simon's weekly newsletter Download Simon's Free ‘Battle Ready Lifestyle' Infographic — https://simon-ward.kit.com/battlereadylifestyle
Episode 218: Statin Therapy Fundamentals What are statins? Zohal: Statins are medications that lower cholesterol by inhibiting the enzyme HMG-CoA reductase, which prevents cholesterol synthesis in the liver. By doing so, statins decrease low-density lipoprotein cholesterol (LDL-C). Why should we lower LDL? Zohal: There are four main lipoproteins that transport fats in blood, including chylomicrons, VLDL, LDL, and HDL. This is where we get our “bad cholesterol” vs. “good cholesterol”. Of these, LDL is most associated with an increased risk in cardiovascular disease, while a higher HDL is associated with lower risk. Thus, reducing LDL subsequently reduces the risk of cardiovascular disease. Arreaza: The lowest LDL I've seen was 25, and the highest HDL was 60. HDL doesn't really have a strict upper limit, but most people fall between 40 and 60. Extremely high HDL—above 100—may not always be protective and can sometimes signal underlying issues. Zohal: My HDL is 70! Statins are used for both primary prevention, meaning preventing cardiovascular disease before it occurs, and secondary prevention, meaning preventing disease progression in patients who already have cardiovascular disease. History of statins. Zohal: In the early 1900's, researchers were studying the association between cholesterol and atherosclerosis, and at that time, they primarily used animal subjects. These studies were initially not taken seriously, because most believed cardiovascular disease in humans were simply due to aging and was not preventable. It wasn't until the middle of the century when researchers began observing that increased levels of LDL and decreased HDL was correlated with an increased rate of heart attacks. This finding prompted interest in determining the pathway of cholesterol synthesis in the human body. Statins were first discovered in the 1970s when researchers identified compounds that inhibit a critical step in cholesterol synthesis. The first statin approved for clinical use was Lovastatin in 1987. Since then, multiple statins have been developed, including Atorvastatin, Rosuvastatin, Simvastatin, and Pravastatin. Further clinical trials in the 1990s and 2000s showed that statins significantly reduce myocardial infarction, stroke, and cardiovascular mortality. Why do Statins Matter in Primary Prevention Zohal: Cardiovascular disease is the most common cause of death worldwide. As previously mentioned, elevated LDL cholesterol contributes to the development of atherosclerotic plaques within arteries, which can lead to heart attack and stroke. By lowering LDL cholesterol and stabilizing plaque formation, statins implemented in a timely manner significantly reduce the risk of atherosclerotic cardiovascular disease. Arreaza: One of the things I love most about primary care is prevention. You're working upstream, often quietly, humbly, helping people avoid disease before it starts. And the truth is—you rarely see the full impact of your actions. You don't get a notification that says, “this patient didn't have a heart attack because of you.” But every time you help someone control their blood pressure, quit smoking, improve their diet, or stay consistent with their medications, you're shifting their tracks. You're reducing risk in ways that may never be fully visible. That's the paradox and the beauty of it: in primary care, your highest victories are often events that never happen. Who Should Receive Statins for Primary Prevention? Zohal: Recommendations slightly differ depending on who you ask. We look to the U.S. Preventive Services Task Force, the American College of Cardiology, and the American Heart Association for their recommendations regarding statins for primary prevention. USPSTF on statins. The U.S. Preventive Services Task Force (or USPSTF for short) is an organization that works to improve the health of people nationwide by making evidence-based recommendations on effective ways to prevent disease & prolong life. They recommend statins for the primary prevention of cardiovascular disease in: Adults 40–75 years old With one or more cardiovascular risk factors such as dyslipidemia, diabetes, hypertension, or smoking AND a 10-year cardiovascular risk of 10% or greater Their recommendations are graded A, B, C, D, and I, depending on the strength of evidence and this is a Grade B recommendation. Arreaza: So, you have to meet all the criteria to receive a statin, according to USPSTF: 40-75, one CV risk factor and a high 10-y ASCVD score, by the way, the ASCVD risk calculator was introduced in 2013 by AHA/ACC. It is available online for free and many EHRs have integrated this tool into their software. For example, if you use EPIC, you can type .ascvd and get a score automatically. What about patients with a cardiovascular risk less than 10%? Zohal: For patients with a 7.5–10% risk, some may offer statin therapy on a case-by-case basis as this is a Grade C recommendation. But I'll get more into this later. Even without trying, every night you go to bed a little wiser. Thanks for listening to Rio Bravo qWeek Podcast. We want to hear from you, send us an email at RioBravoqWeek@clinicasierravista.org, or visit our website riobravofmrp.org/qweek. See you next week! _____________________ References: Grundy SM, et.al, Guideline on the Management of Blood Cholesterol: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. Circulation. 2019 Jun 18;139(25):e1082-e1143. doi: 10.1161/CIR.0000000000000625. Epub 2018 Nov 10. Erratum in: Circulation. 2019 Jun 18;139(25):e1182-e1186. doi: 10.1161/CIR.0000000000000698. Erratum in: Circulation. 2023 Aug 15;148(7):e5. doi: 10.1161/CIR.0000000000001172. PMID: 30586774; PMCID: PMC7403606. https://pubmed.ncbi.nlm.nih.gov/30586774/ U.S. Preventive Services Task Force. (2022, August 23). Statin use for the primary prevention of cardiovascular disease in adults: Preventive medication.https://www.uspreventiveservicestaskforce.org/uspstf/recommendation/statin-use-in-adults-preventive-medicatio American College of Cardiology ASCVD Risk Estimator: https://tools.acc.org/ascvd-risk-estimator-plus/#!/calculate/estimate/ Guideline Central. (2026, March). ACC/AHA dyslipidemia guideline spotlight (March 2026).https://www.guidelinecentral.com/insights/mar-2026-accaha-dyslipidemia-guideline-spotlight/ Endo A. A historical perspective on the discovery of statins. Proc Jpn Acad Ser B Phys Biol Sci. 2010;86(5):484-93. doi: 10.2183/pjab.86.484. PMID: 20467214; PMCID: PMC3108295. https://pubmed.ncbi.nlm.nih.gov/20467214/ Theme song, Works All The Time by Dominik Schwarzer, YouTube ID: CUBDNERZU8HXUHBS, purchased from https://www.premiumbeat.com/.
What if everything you've been told about cholesterol, statins, and hormones isn't the full picture?In this eye-opening conversation, I sit down with Elizabeth Plourde, who brings decades of research and firsthand experience inside the medical system. We explore how “normal” ranges have changed over time, why so many people are prescribed medications without deeper investigation, and what your body actually needs to function optimally.This episode is about empowerment—understanding your body, asking better questions, and not blindly outsourcing your health decisions.What We Cover
Statins are one of the most commonly prescribed medications for managing high cholesterol, but many people experience muscle pain, fatigue, and weakness while taking them. In this episode of the Pain and Performance Podcast, Dr. Derrick Hines explains the science behind statin-associated muscle symptoms (SAMS) and why these issues occur in some patients. He breaks down how statins can affect CoQ10 levels and mitochondrial energy production, leading to muscle dysfunction. The episode also explores evidence-based lifestyle strategies, metabolic interventions, and supplement options that may help support cardiovascular health for those who struggle to tolerate statins.In This Episode- What statin-associated muscle symptoms (SAMS) are and why they occur- How statins can affect CoQ10, mitochondrial energy production, and muscle function- Important tests that give a clearer picture of cardiovascular risk beyond a standard lipid panel- Lifestyle strategies including nutrition, fasting protocols, and exercise to improve metabolic health- Supplements and therapies that may support cholesterol balance and vascular healthTikTok:https://www.tiktok.com/@drderrickInstagram:https://www.instagram.com/derrickbhines/Youtube:https://www.youtube.com/@DrDerrick
What if everything you've been told about cholesterol, statins, and hormones isn't the full picture?In this eye-opening conversation, I sit down with Elizabeth Plourde, who brings decades of research and firsthand experience inside the medical system. We explore how “normal” ranges have changed over time, why so many people are prescribed medications without deeper investigation, and what your body actually needs to function optimally.This episode is about empowerment—understanding your body, asking better questions, and not blindly outsourcing your health decisions.What We Cover
What if everything you've been told about cholesterol, statins, and hormones isn't the full picture?In this eye-opening conversation, I sit down with Elizabeth Plourde, who brings decades of research and firsthand experience inside the medical system. We explore how “normal” ranges have changed over time, why so many people are prescribed medications without deeper investigation, and what your body actually needs to function optimally.This episode is about empowerment—understanding your body, asking better questions, and not blindly outsourcing your health decisions.What We Cover
What if everything you've been told about cholesterol, statins, and hormones isn't the full picture?In this eye-opening conversation, I sit down with Elizabeth Plourde, who brings decades of research and firsthand experience inside the medical system. We explore how “normal” ranges have changed over time, why so many people are prescribed medications without deeper investigation, and what your body actually needs to function optimally.This episode is about empowerment—understanding your body, asking better questions, and not blindly outsourcing your health decisions.What We Cover
What if everything you've been told about cholesterol, statins, and hormones isn't the full picture?In this eye-opening conversation, I sit down with Elizabeth Plourde, who brings decades of research and firsthand experience inside the medical system. We explore how “normal” ranges have changed over time, why so many people are prescribed medications without deeper investigation, and what your body actually needs to function optimally.This episode is about empowerment—understanding your body, asking better questions, and not blindly outsourcing your health decisions.What We Cover
What if everything you've been told about cholesterol, statins, and hormones isn't the full picture?In this eye-opening conversation, I sit down with Elizabeth Plourde, who brings decades of research and firsthand experience inside the medical system. We explore how “normal” ranges have changed over time, why so many people are prescribed medications without deeper investigation, and what your body actually needs to function optimally.This episode is about empowerment—understanding your body, asking better questions, and not blindly outsourcing your health decisions.What We Cover
The first time Dr. Vickie learned her cholesterol was high, she was 26 years old and surviving on hospital cafeteria hamburgers and Coca-Cola. High cholesterol runs in her family — and that personal history is exactly why she's passionate about helping you understand yours. In this episode, Dr. Vickie takes you to mini medical school for a deep dive into cholesterol: what it is, where it comes from, why your body needs it, and what the brand new 2026 guidelines say about managing it. She breaks down the PREVENT heart disease calculator — a tool built on data from millions of people — and explains exactly what numbers you need to know your 10-year risk for heart attack and stroke. You'll learn why diet and exercise can move the needle more than doctors once thought, which foods raise and lower your LDL, and the truth about statins — including the real side effect profile and why some of the fear around them is rooted in misinformation rather than science. In this episode: Why your brain cholesterol has nothing to do with your blood cholesterol LDL targets for low, high, and very high-risk individuals How fiber and saturated fat affect your cholesterol more than eggs ever will The Mediterranean and Portfolio diets for heart health An honest, balanced look at statins — side effects, myths, and when they make sense How the Healthy Looks Great on You LAB is focusing on heart health all of April Healthy Looks Great on you the LAB Cholesterol: Good vs. Bad PREVENT heart risk calculator Cholesterol guidelines 2026
TODAY ON THE ROBERT SCOTT BELL SHOW: White House Tightens Grip on HHS, Ozempic Fallout Grows, Hidden Risks of Weight Loss Jabs, SCOTUS Mandate Lessons, Aragallus Lamberti, Truth About Vaccine Injuries, 29 States Reject RFK Guidance, Pediatric Psych Drugs, Statins at 30, Doomsday Believers No Longer Fringe, and MORE! https://robertscottbell.com/white-house-tightens-grip-on-hhs-ozempic-fallout-grows-hidden-risks-of-weight-loss-jabs-scotus-mandate-lessons-aragallus-lamberti-truth-about-vaccine-injuries-states-reject-federal-vaccine-guida/ Purpose and Character The use of copyrighted material on the website is for non-commercial, educational purposes, and is intended to provide benefit to the public through information, critique, teaching, scholarship, or research. Nature of Copyrighted Material Weensure that the copyrighted material used is for supplementary and illustrative purposes and that it contributes significantly to the user's understanding of the content in a non-detrimental way to the commercial value of the original content. Amount and Substantiality Our website uses only the necessary amount of copyrighted material to achieve the intended purpose and does not substitute for the original market of the copyrighted works. Effect on Market Value The use of copyrighted material on our website does not in any way diminish or affect the market value of the original work. We believe that our use constitutes a 'fair use' of any such copyrighted material as provided for in section 107 of the U.S. Copyright Law. If you believe that any content on the website violates your copyright, please contact us providing the necessary information, and we will take appropriate action to address your concern.
Support your health journey with our private practice! Explore comprehensive lab testing, functional assessments, and expert guidance for your wellness journey. Find exclusive offers for podcast listeners at nutritionwithjudy.com/podcast. _____**Podcast Update: It looks like I accidentally switched the terms: absolute risk reduction vs relative risk reduction. Regardless of the terminologies, the point was to see what funny games statisticians will use for marketing pharma drugs (and this happens in a lot of types of marketing...) To see a clear write-up of the absolute risk vs relative risk, you can read an article I shared about it: https://www.nutritionwithjudy.com/old-newsletter/why-statins-dont-stop-heart-attacks/In this episode, I walk through why statins are prescribed (especially with LDL above 190 mg/dL or with type 2 diabetes), and I explain how statin marketing can make the benefits look bigger than they really are by using relative risk instead of absolute risk. I also cover major concerns I see with statins, including nutrient depletion (like CoQ10) and potential impacts on muscle function over time. Make sure to listen to the full interview to learn more.The statin numbers (the what, why)Lipitor ad: relative vs absolute risk reductionStatin efficacy studies (and risks)Statins reduce nutrient status (including CoQ10)Risks of low cholesterolWhat to test and track for heart diseaseNew book cover _____EPISODE RESOURCES Join the NewsletterCarnivore Diet Cholesterol Labs Cardiovascular Blood TestStatin Use Is Associated With a Decline in Muscle Function and Mass Over Time (PubMed)Should You Take a Statin for Your High Cholesterol? (Yale Medicine)Lipitor Ad Highlighting Relative Risk Reduction (36%) vs Absolute Risk (3% vs 2%) (ResearchGate Figure)Atorvastatin Decreases Blood Coenzyme Q10 in Patients at Risk for CVD and Stroke (JAMA/Arch Neurol)Lipitor: Why It Remains the Best-Selling Drug in Pharmaceutical History (Accio)Heart Statistics: Cardiovascular Disease Statistics for the UK (British Heart Foundation)WHO Mortality Database (World Health Organization)Robert Jarvik (Artificial Heart Developer) (Wikipedia)Pfizer, Lipitor (atorvastatin calcium) print advertisement featuring Robert Jarvik, ca. 2006–2008.____FIND JUDY CHO⛑️Work with Us: https://empowerfunctionalhealth.com/services/