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Life is longer for “those who think young”; Watching too much TV may shrink your brain (literally!); Diet and supplements may help lupus; When a high-fiber diet before surgery may be inadvisable; Your mouth may be the gateway to your overall health and longevity.
What are normal cholesterol levels, and what do your numbers really mean for your heart health? Discover the truth about good and bad cholesterol, what your cholesterol levels reveal, and how to lower cholesterol naturally to support your overall health. 0:00 What are normal cholesterol levels?0:53 Normal cholesterol levels explained1:46 LDL cholesterol levels and heart disease prevention2:44 What is LDL?4:36 Small-dense LDL and insulin resistance 5:17 The problem with cholesterol guidelines8:11 Statins vs. natural remedies to lower cholesterol9:46 What causes insulin resistance?
Is there evidence for statins in the treatment of aortic valve stenosis?How the bacteria behind gum disease can affect heart healthWouldn't it be better to resume taking probiotics after finishing a round of antibiotics?Would it be safe to take olive leaf extract with amoxicillin?I'm considering surgery for varicose veins. Is this just a temporary fix? Can they return?
This week, we reviewed the latest on cyclosporiasis. Hint: DON’T stop eating produce. Shop local! Go the farmer’s markets and talk to the actual farmers about their growing practices! Then, it was all about cholesterol. There’s a new drug on the market, an oral PCSK-9 inhibitor, before which there were only injectables. Is it a […]
In episode 83 of Going anti-Viral, Dr Steven Grinspoon joins host Dr Michael Saag to provide an update on guidelines for statin use in people with HIV based on results from the REPRIEVE trial. Dr Grinspoon is a Professor of Medicine at Harvard Medical School and a clinician in the Neuroendocrine and Pituitary Tumor Clinical Center and faculty member at the Massachusetts General Hospital. He is a clinical researcher who studies hypothalamic control of body weight and fat distribution in obesity and lipodystrophy with a focus on the metabolic and cardiovascular consequences of visceral fat accumulation. Dr Grinspoon is the author of more than 200 peer-reviewed publications and serves as the chief of the Massachusetts General Metabolism Unit and the director of the Nutrition Obesity Research Center at Harvard. Dr Grinspoon and Dr Saag discuss the latest findings from the REPRIEVE trial and provide updates on statin guidelines for people with HIV as well as providing insights into cardiovascular risk management. They discuss the safety and efficacy of statins and the role of cardiovascular risk calculators in clinical practice in addition to discussing the impact of low-density lipoprotein (LDL) cholesterol and inflammation on cardiovascular risk. Dr Grinspoon also offers his outlook for where further research is needed based on the outcomes of the REPRIEVE trial.0:00 – Introduction 1:33 – Overview of the REPRIEVE trial findings2:44 – Changes in statin guidelines for people with HIV 6:51 – Safety and efficacy of statins9:09 – Use of statins and diabetes risk11:16 – Cardiovascular risk calculators16:00 – Statin use and blood pressure17:14 – Impact of LDL cholesterol and inflammation on cardiovascular risk24:08 – Future directions in cardiovascular research for people with HIV Resources:Going anti-Viral: Episode 56 – Cardiovascular Health in People with HIV – Dr Steven GrinspoonApple Podcasts:https://podcasts.apple.com/us/podcast/the-management-of-cardiovascular-health-in-patients/id1713226144?i=1000725697103 YouTube:https://youtu.be/297vweZ5bjQ REPRIEVE Trial: https://www.reprievetrial.org/ __________________________________________________Produced by IAS-USA, Going anti–Viral is a podcast for clinicians involved in research and care in HIV, its complications, and other viral infections. This podcast is intended as a technical source of information for specialists in this field, but anyone listening will enjoy learning more about the state of modern medicine around viral infections.Going anti-Viral's host is Dr Michael Saag, a physician, prominent HIV researcher at the University of Alabama at Birmingham, and volunteer IAS–USA board member. In most episodes, Dr Saag interviews an expert in infectious diseases or emerging pandemics about their area of specialty and current developments in the field. Other episodes are drawn from the IAS–USA vast catalogue of panel discussions, Dialogues, and other audio from various meetings and conferences. Email podcast@iasusa.org to send feedback, show suggestions, or questions to be answered on a later episode.Follow Going anti-Viral on: Apple Podcasts YouTubeXFacebookInstagram...
Credits: 0.25 AMA PRA Category 1 Credit™ CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-495 Overview: Statin prescription labels and case reports list a variety of potential treatment-related adverse effects that often raise concerns about their safety. In this episode, we review the evidence for such effects from a recently published study of statin therapy, giving you confidence to counsel worried patients. Episode resource links: Explain the concerns over potential negative effects from statin use Outline the latest research demonstrating statin safety Guest: Robert A. Baldor MD, FAAFP Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at FranklySpeaking@pri-med.com The views expressed in this podcast are those of Dr. Domino and his guests and do not necessarily reflect the views of Pri-Med.
Credits: 0.25 AMA PRA Category 1 Credit™ CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-495 Overview: Statin prescription labels and case reports list a variety of potential treatment-related adverse effects that often raise concerns about their safety. In this episode, we review the evidence for such effects from a recently published study of statin therapy, giving you confidence to counsel worried patients. Episode resource links: Explain the concerns over potential negative effects from statin use Outline the latest research demonstrating statin safety Guest: Robert A. Baldor MD, FAAFP Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at FranklySpeaking@pri-med.com The views expressed in this podcast are those of Dr. Domino and his guests and do not necessarily reflect the views of Pri-Med.
The Real Truth About Health Free 17 Day Live Online Conference Podcast
Stents don't prevent attacks. Statins don't reverse disease. Only lifestyle change addresses the root cause. #StentMyth #StatinLimits #LifestyleMedicine #HealthTalks
Dr Chris Smith and Clarence Ford return to answer your questions. Why do wombats produce cube-shaped droppings? Does sleeping position affect dreams? Can we predict penalty shootout winners? What do penalty statistics show about power vs placement? What are the pros and cons of statins? Is a cloned tree's DNA young or old? Why do golf balls have dimples? Could you outdrive Rory McIlroy on Mars? Like this podcast? Please help us by supporting the Naked Scientists
Dr Chris Smith and Clarence Ford return to answer your questions. Why do wombats produce cube-shaped droppings? Does sleeping position affect dreams? Can we predict penalty shootout winners? What do penalty statistics show about power vs placement? What are the pros and cons of statins? Is a cloned tree's DNA young or old? Why do golf balls have dimples? Could you outdrive Rory McIlroy on Mars? Like this podcast? Please help us by supporting the Naked Scientists
Did you know the very medication doctors push to "protect" your heart could be wrecking your brain, hormones, and mood? I've watched statins destroy lives, including my father's, and it's time to address the issues with the meds. I am joined by chiropractor Joel Boheimer, founder of the supplement line Regenerate, to break down why nattokinase is gaining popularity for heart health. Joel walks us through the research behind this fibrin-dissolving enzyme. He explains why cholesterol isn't the villain we've been told it is, and how the wrong form of calcium affects your arteries and joints. We also get into vitamin K2, ellagic acid, and why regenerative, whole-food sourcing changes everything about how a supplement performs in your body. If you're worried about your heart or just tired of being handed a prescription instead of an explanation, this conversation will change how you think about your next cardiologist visit. "Research shows that higher levels of cholesterol are protective to longevity, heart attack, strokes, and cancers." ~ Dr. Joel Bohemier In This Episode: - What is nattokinase, and what are its benefits? - Why statins are dangerous - Statins linked to rise in dementia - Nattokinase use after 2020 jabs - Regenerate's farming philosophy - The research behind Regenerate's supplements - An overview of CardioNK's ingredients - Vitamin K2 and calcium placement - Ellagic acid and urolithins - Bacillus subtilis and gut health benefits - Where to get CardioNK and recommended dosage Products & Resources Mentioned: Regenerate's CardioNK: Get it at a special discount at: https://regeneratecompany.com/pages/myers?uid=2&oid=2&affid=9 Bon Charge Red Light Face Mask: Get 15% off sitewide, plus free shipping and a 12-month warranty, with code WENDY at https://boncharge.com/ Tru Energy Skincare Bio Adaptive Hydration Oil: Try the oil and save up to $197 at trytruenergy.com/wendy5 Organifi Collagen: Save 20% with code MYERSDETOX at https://organifi.com/myersdetox Heavy Metals Quiz: Take the quiz at https://heavymetalsquiz.com About Dr. Joel Bohemier: Dr. Joel Bohemier is a second-generation chiropractor and founder of Regenerate, a supplement company built on a simple idea: the health of people and the health of the planet are connected. A longtime advocate for natural health and medical freedom, Dr. Bohemier has spent his career helping people take ownership of their health rather than just manage symptoms. He owns several chiropractic and wellness practices in Southwest Florida and is a frequent speaker on organic nutrition, detoxification, and regenerative health. He co-founded Stand for Health Freedom, serves on the advisory board of GreenMedInfo.com, and is a member of the Global Wellness Forum's Legislative Innovation Council. Learn more about Regenerate supplements at https://regeneratecompany.com/ Disclaimer The Myers Detox Podcast was created and hosted by Dr. Wendy Myers. This podcast is for information purposes only. Statements and views expressed on this podcast are not medical advice. This podcast, including Wendy Myers and the producers, disclaims responsibility for any possible adverse effects from using the information contained herein. The opinions of guests are their own, and this podcast does not endorse or accept responsibility for statements made by guests. This podcast does not make any representations or warranties about guests' qualifications or credibility. Individuals on this podcast may have a direct or indirect financial interest in products or services referred to herein. If you think you have a medical problem, consult a licensed physician.
Transforming your health is more fun with friends! Join Chef AJ's Exclusive Plant-Based Community. Become part of the inner circle and start simplifying plant-based living - with easy recipes and expert health guidance. Find out more by visiting: https://community.chefaj.com/ ORDER MY NEW BOOK SWEET INDULGENCE!!! https://www.amazon.com/Chef-AJs-Sweet-Indulgence-Guilt-Free/dp/1570674248 or https://www.barnesandnoble.com/w/book/1144514092?ean=9781570674242 GET MY FREE INSTANT POT COOKBOOK: https://www.chefaj.com/instant-pot-download MY BEST SELLING WEIGHT LOSS BOOK: https://www.amazon.com/dp/1570674086?tag=onamzchefajsh-20&linkCode=ssc&creativeASIN=1570674086&asc_item-id=amzn1.ideas.1GNPDCAG4A86S Disclaimer: This podcast does not provide medical advice. The content of this podcast is provided for informational or educational purposes only. It is not intended to be a substitute for informed medical advice or care. You should not use this information to diagnose or treat any health issue without consulting your doctor. Always seek medical advice before making any lifestyle changes. Watch TrueNorth Health TV for FREE https://www.healthpromoting.com/tnhtv Please get the book here now! To get a copy signed by Dr. Goldhamer: https://www.healthpromoting.com/can-fasting-save-your-life To buy on Amazon: https://www.amazon.com/dp/1570674191?linkCode=ssc&tag=onamzchefajsh-20&creativeASIN=1570674191&asc_item-id=amzn1.ideas.1GNPDCAG4A86S&ref_=aip_sf_list_spv_ofs_mixed_d_asin Dr. LIsle and Dr. Goldhamer's book The Pleasure Trap: https://www.amazon.com/dp/1570671974?tag=onamzchefajsh-20&linkCode=ssc&creativeASIN=1570671974&asc_item-id=amzn1.ideas.1GNPDCAG4A86S Dr. Alan Goldhamer is the co-founder of TrueNorth Health Center, a state-of-the-art facility that provides medical and chiropractic services, psychotherapy and counseling, as well as massage and bodywork. He is also director of the Center's groundbreaking residential health education program. Dr. Goldhamer has supervised the fasts of thousands of patients. Under his guidance, the Center has become one of the premier training facilities for doctors wishing to gain certification in the supervision of therapeutic fasting. Dr. Goldhamer was the principal investigator in two landmark studies. The first: "Medically Supervised Water-Only Fasting in the Treatment of Hypertension" appeared in the June 2001 issue of the Journal of Manipulative and Physiological Therapeutics. Its publication marked a turning point in the evolution of evidence supporting the benefits of water-only fasting. The second study: "Medically Supervised Water-Only Fasting in the Treatment of Borderline Hypertension," appeared in the October 2002 issue of the Journal of Alternative and Complementary Medicine. Currently, Dr. Goldhamer is directing a team that is developing a prospective study, incorporating random assignment and long-term follow-up on the cost and clinical outcomes in the treatment of diabetes and high blood pressure with fasting and a health-promoting diet. After completing his chiropractic education at Western States Chiropractic College in Portland, Oregon, Dr. Goldhamer traveled to Australia, where he became licensed as an osteopathic physician. He is the author of The Health Promoting Cookbook and co-author of The Pleasure Trap: Mastering The Hidden Force That Undermines Health and Happiness. Dr. Goldhamer is speaking at the NHA Virtual Conference (June 27-30, 2024). Use this link to get your tickets now: https://events.ringcentral.com/events/nha-conference-2024/registration?utm_campaign=Chef+AJ&utm_source=Affiliate For coaching services: https://www.healthpromoting.com/clinic-services/health-services/coaching-services To register for a stay at TrueNorth: https://www.healthpromoting.com/registration
Episode 2826 - Vinnie Tortorich and Anna Vocino discuss trying new things, Anna's grocery store plans, and whether statins are really normal. https://vinnietortorich.com/2026/07/are-statins-really-normal-episode-2826 PLEASE SUPPORT OUR SPONSORS Pure Vitamin Club Pure Coffee Club NSNG® Foods VILLA CAPPELLI EAT HAPPY KITCHEN YOU CAN WATCH THIS EPISODE ON YOUTUBE - @FitnessConfidential Podcast Vinnie's workout videos are available to purchase! Choose from a 2-day, 4-day, or 6-day workout–or buy all three at a discount! TO PURCHASE VINNIE'S WORKOUT VIDEOS, CLICK THIS LINK: https://vinnietortorich.com/workout Are Statins Really Normal? Vinnie encourages people to go out and live life by trying new things. (4:00) There's a recent drug, similar to a statin, called Repatha. But is it better? (13:00) Statins were originally developed for specific heart-related issues; however, they have now gained traction as almost "normal," even though they weren't intended to be. Please do your own research and advocate for yourself, because no one is coming to save you. Society has normalized taking meds instead of normalizing better health. Pure Vitamin Club has revamped its website and added more offerings! (24:00) Anna has an update on her grocery store plans: Eat Happy Kitchen is pulling out of Kroger's Western divisions. (33:00) Kroger has decided to reduce the number of sauces it carries and is going for non-premium items. Be sure to go to Kroger-affiliated stores and buy up what you can! Anna's products are moving forward and earning certifications to ensure customers know Eat Happy Kitchen can be trusted to be the best! She is still trying to get into other grocery store chains, however. (35:00) A recent medical journal article was sent to Vinnie. The article's headline suggests people are poisoning themselves with semaglutides. Is that accurate? (42:00) The article suggests that several weight loss drugs were released before side effects were clearly understood. Movies, rom-coms, and Christmas movies vs. not Christmas movies? (48:00) Check out the Aletha Hip HookTM that Vinnie uses to reduce pain and increase mobility: You can purchase your own through Vinnie's website here: https://vinnietortorich.com/hook Anna's products are now linked to PureVitamin Club's website. Look under the "Food and Snacks" section to purchase them there, too. https://purevitaminclub.com/collections/food-and-snacks Vinnie hopes to add other products as well, all of which will be health-related. The NSNG® VIP GROUP IS NOW CLOSED AGAIN AS OF SUNDAY, MARCH 15TH Anna's next cookbook, Eat Happy Cocktail Hour, is filled with cocktails, mocktails, and appetizers and is available for pre-order right now. If you pre-order, you'll get bonus goodies! You can preorder from a wide variety of booksellers at https://eathappycocktailhour.com/ Please save your receipt from wherever you preorder; you'll need it for your bonuses! Physical Release Date is October 2026 You can book a consultation with Vinnie to get guidance on your goals. https://vinnietortorich.com/phone-consultation-2/ More News Serena has added some of her clothing suggestions and beauty product suggestions to Vinnie's Amazon Recommended Products link. Self Care, Beauty, and Grooming Products that Actually Work! https://www.amazon.com/shop/vinnietortorich/list/3GPVU29UHHPMY?ref_=aipsflist Don't forget to check out Serena Scott Thomas on Days of Our Lives on Peacock. "Dirty Keto" is available on Amazon! You can purchase or rent it here.https://amzn.to/4d9agj1 Please make sure to watch, rate, and review it! Eat Happy Italian, Anna's second cookbook, is available! You can go to https://eathappyitalian.com You can order it from Vinnie's Book Club. https://amzn.to/3ucIXm Anna's recipes are in her cookbooks, on her website, and on Substack —they will spice up your day! https://annavocino.substack.com/ PURCHASE DIRTY KETO (2024) The documentary launched in August 2024! Order it TODAY! This is Vinnie's fourth documentary in just over five years. Visit my new Documentaries HQ to find my films everywhere: https://vinnietortorich.com/documentaries Then, please share my fact-based, health-focused documentary series with your friends and family. Additionally, the more views it receives, the better it ranks, so please watch it again with a new friend! REVIEWS: Please submit your REVIEW after you watch my films. Your positive REVIEW does matter! PURCHASE BEYOND IMPOSSIBLE (2022) Visit my new Documentaries HQ to find my films everywhere: https://vinnietortorich.com/documentaries FAT: A DOCUMENTARY 2 (2021) Visit my new Documentaries HQ to find my films everywhere: https://vinnietortorich.com/documentaries FAT: A DOCUMENTARY (2019) Visit my new Documentaries HQ to find my films everywhere: https://vinnietortorich.com/documentaries
Is it safe to stop statins “cold turkey”? Can the supplement ingredient HMB counteract age-related muscle loss? Researchers may have discovered the key to development of a true fat-burning weight loss medication; Can a mammogram yield clues about cardiovascular risk? Their bottom line threatened by GLP-1 weight loss drugs, BIg Food tweaks portion sizes, adds spices and flavorings to pique blunted appetites; Vitamins A & D may improve lung health for asthma sufferers; When it comes to thyroid medication prescribing, treat the numbers or treat the patient?
Episode 2825 - Vinnie Tortorich speaks with Dr. Philip Ovadia to discuss confusion around LDL, his second book, and why food matters. https://vinnietortorich.com/2026/07/why-food-matters-dr-philip-ovadia-episode-2825 PLEASE SUPPORT OUR SPONSORS Pure Vitamin Club Pure Coffee Club NSNG® Foods VILLA CAPPELLI EAT HAPPY KITCHEN YOU CAN WATCH THIS EPISODE ON YOUTUBE - @FitnessConfidential Podcast Vinnie's workout videos are available to purchase! Choose from a 2-day, 4-day, or 6-day workout–or buy all three at a discount! TO PURCHASE VINNIE'S WORKOUT VIDEOS, CLICK THIS LINK: https://vinnietortorich.com/workout Why Food Matters Dr. Philip Ovadia is a cardiologist and heart surgeon. Heart disease is still the number one killer in the United States. (6:30) Dr. Ovadia's first book is a best seller you can find in Vinnie's book club: Stay Off My Operating Tablehttps://amzn.to/3SelRrs Even athletes in what appears to be extraordinary good health can still suffer from heart disease and cardiac arrest. (14:00) Heavy carb cycling or loading could be contributing to it. (16:00) How important is monitoring LDL only? (25:00) Small, dense LDL particles are important to monitor. Statins lower the large-particle LDL, which is the healthy form, but not the small-particle LDL. Insulin resistance and chronic inflammation are drivers of "bad" LDL. Dr. Ovadia explains how Repatha works. (30:00) He also explains some complications during its trials. A challenge of the Western medical system is that specialties have become too compartmentalized. (35:30) Pre-Order Dr. Ovadia's second book. Pre-orders are important to the algorithm. (Stay Off My Kitchen Table) He shares a story about his friend and ghost writer, Joshua. (41:00) Pre-order Dr. Ovadia's book using this link: https://ifixhearts.com/books/ Dr. Ovadia explains the importance of knowing what food goes into your body and what it does (or doesn't) for you. The vegan diet is propaganda. Dr. Ovadia explains. (54:00) Technology and testing methods have improved, and imaging is now clearer. Also, you may not be limited to dealing only with a local doctor; telehealth may now be available to you. You can also find Dr. Ovadia on socials and at iFixHearts.com. Anna's products are now linked to PureVitamin Club's website. Look under the "Food and Snacks" section to purchase them there, too. https://purevitaminclub.com/collections/food-and-snacks Vinnie hopes to add other products as well, all of which will be health-related. The NSNG® VIP GROUP IS NOW CLOSED AGAIN AS OF SUNDAY, MARCH 15TH Anna's next cookbook, Eat Happy Cocktail Hour, is filled with cocktails, mocktails, and appetizers and is available for pre-order right now. If you pre-order, you'll get bonus goodies! You can preorder from a wide variety of booksellers at https://eathappycocktailhour.com/ Save your receipt from wherever you preorder, you'll need it for your bonuses! Physical Release Date is October 2026 You can book a consultation with Vinnie to get guidance on your goals. https://vinnietortorich.com/phone-consultation-2/ More News Serena has added some of her clothing suggestions and beauty product suggestions to Vinnie's Amazon Recommended Products link. Self Care, Beauty, and Grooming Products that Actually Work! https://www.amazon.com/shop/vinnietortorich/list/3GPVU29UHHPMY?ref_=aipsflist Don't forget to check out Serena Scott Thomas on Days of Our Lives on the Peacock channel. "Dirty Keto" is available on Amazon! You can purchase or rent it here.https://amzn.to/4d9agj1 Please make sure to watch, rate, and review it! Eat Happy Italian, Anna's second cookbook, is available! You can go to https://eathappyitalian.com You can order it from Vinnie's Book Club. https://amzn.to/3ucIXm Anna's recipes are in her cookbooks, on her website, and on Substack —they will spice up your day! https://annavocino.substack.com/ PURCHASE DIRTY KETO (2024) The documentary launched in August 2024! Order it TODAY! This is Vinnie's fourth documentary in just over five years. Visit my new Documentaries HQ to find my films everywhere: https://vinnietortorich.com/documentaries Then, please share my fact-based, health-focused documentary series with your friends and family. Additionally, the more views it receives, the better it ranks, so please watch it again with a new friend! REVIEWS: Please submit your REVIEW after you watch my films. Your positive REVIEW does matter! PURCHASE BEYOND IMPOSSIBLE (2022) Visit my new Documentaries HQ to find my films everywhere: https://vinnietortorich.com/documentaries FAT: A DOCUMENTARY 2 (2021) Visit my new Documentaries HQ to find my films everywhere: https://vinnietortorich.com/documentaries FAT: A DOCUMENTARY (2019) Visit my new Documentaries HQ to find my films everywhere: https://vinnietortorich.com/documentaries
Dealing with the heat - Europeans' disdain for air conditioningI have scaly and bumpy areas on my scalp that itch!Did homeopathic human growth hormone increase my cholesterol?
→ Ora Organic | Real ingredients, planet-friendly packaging, easy to love. Head to https://ora.organic/pages/drg and use my code HEALTHYSELF30 to enjoy 30% off your first Ora order today. → Puori | Go to https://puori.com/DRG and use the code DRG at checkout to get 32% off your first Puori Creatine+ subscription order. → Santa Barbara Chocolate | CocoaDynamics available at https://SantaBarbaraChocolate.com. Use code DRG20 for 20% off. Episode Description: Social media has convinced women that they need to lower their cortisol to lose belly fat, sync their workouts to their menstrual cycle, eat differently depending on their cycle phase, avoid heavy lifting to stay lean, and take a stack of longevity supplements to live longer. Dr. Mary Pardee is here to call most of that what it is. Dr. Mary is a naturopathic and functional medicine doctor, one of Dr. G's closest friends, and one of the most evidence-based voices in the wellness space. This is her third time on Heal Thy Self and she is not holding back. From LDL cholesterol to VO2 max to the Mediterranean diet to cold plunge, she is cutting through the noise and giving women the clearest, most direct framework for actually living longer. In this episode, you'll discover: • Why LDL cholesterol is causative for heart disease the way smoking is causative for lung cancer, what numbers to actually target at different life stages, and why plaque formation begins in your 20s • The truth about cycle syncing workouts and food, why it is a marketing tactic designed to confuse a vulnerable population into buying something, and what the research actually says about training through your cycle • How to structure protein intake for muscle building, the exact grams per kilogram targets for different goals, and why women are still chronically under eating protein even in 2026 Plus the labs every woman should be running, what a DEXA scan actually reveals about body composition, and why cold plunge has no longevity evidence behind it while sauna does. Find Dr. Amy Pardee: Website: https://www.modrnmed.com/ Instagram: https://www.instagram.com/dr.marypardee Timestamps: 0:00 - Intro 2:07 - Rapid Fire: Cortisol, LDL, Heavy Lifting & Cycle Syncing — Myth or Fact? 5:30 - How Dr. Mary Became the Most Evidence-Based Naturopathic Doctor Dr. G Knows 9:10 - The Vulnerable Populations Being Targeted by Wellness Influencers 11:45 - The Truth About Cortisol and Belly Fat (And Who This Advice Is Actually Hurting) 15:00 - Calories vs. Whole Foods: Why "Just Eat Clean" Is Gaslighting a Lot of People 19:00 - DEXA Scans, Skinny Fat & Why Women Often Need to Add Muscle, Not Lose Weight 22:30 - How Much Protein Women Actually Need and Why Most Are Undereating It 26:00 - Animal Protein vs. Plant Protein: Has Dr. Mary Changed Her Mind? 28:30 - Heart Disease Is Still the #1 Killer — Here's Why That Hasn't Changed 31:00 - LDL Is Causative for Heart Disease, Full Stop (And Why the Nuance Is Misleading People) 35:00 - What LDL Numbers Should Actually Trigger Treatment 37:30 - Should People in Their 30s Be on Statins? Dr. Mary Says Yes 39:00 - How Much Can Diet Actually Lower Your LDL? The 20% Reality 42:00 - The Mediterranean Diet vs. Keto vs. Carnivore: What the Research Actually Supports 45:00 - VO2 Max: What It Measures, Why It Matters & Whether You Need to Test It 49:30 - Cycle Syncing Your Workouts and Diet: Social Media Trash 52:30 - Cold Plunge vs. Sauna for Longevity: What the Evidence Actually Shows 54:30 - The Labs Every Person Should Ask Their Doctor to Run 58:00 - One Thing Dr. Mary Wants Every Woman to Walk Away With Learn more about your ad choices. Visit megaphone.fm/adchoices
Why are Americans paying MORE for healthcare with WORSE results? Dr. John Abramson was a family physician for 20 years who left his practice in 2002 to devote himself to researching the commercial takeover of medical knowledge. He has since served as an expert in medical litigation, served as a consultant to the FBI & US Dept of Justice & authored two books – Overdosed America & Sickening. In this episode, he shares how the power of public conversation could be the key to sustainable change in the American medical system. He also explores why your doctor is a captured agent, answers the question, are Americans too lazy for healthy lifestyle changes?, the drug that that killed more Americans than the Vietnam War & the specific wording you'll need at your next doctor's appointment to help your doctor help you. This episode originally aired June 3, 2024. If you liked this episode, you'll also like episode 204: ARE LOW FAT DIETS HEALTHY? HEART HEALTH & HECKLERS [REMASTERED] Guest: https://a.co/d/9cgu9Ci Sponsors: https://www.historicpensacola.org/about-us/ 2:56 A 9/11 every day: 1 million excess American deaths a year6:42 The good news: 80-90% of your health is in your control9:53 96% of medical research is about drugs, not health11:53 The "Americans are just lazy" myth, debunked13:42 A landmark study: lifestyle beat metformin at preventing diabetes15:47 Why doctors default to the pill16:09 Statins cut heart disease risk 20%. Lifestyle cuts it 80%18:44 How to get real answers out of your doctor21:14 Your doctor might know less about nutrition than you think21:47 "A captured agent": why doctors trust bad information23:42 The peer review system doesn't work like you think25:45 Is medical research being ghostwritten?27:01 The Vioxx case: 60,000 dead, nobody arrested28:15 Inside Merck's cover-up email36:07 Why the FDA won't stop the ad blitz38:20 How to actually negotiate with your doctor39:32 The real math behind whether you need a statin41:24 What if being an informed patient gets you fired by your doctor?45:31 Where to find Abramson's books, Overdosed America and SickeningRequest to join my private Facebook Group, MFR Curious Insiders: https://www.facebook.com/share/g/1BAt3bpwJC/Follow me in all the places:https://www.meredithforreal.com/ https://www.instagram.com/the_curiousintrovert/ meredith@meredithforreal.comhttps://www.youtube.com/meredithforreal https://www.facebook.com/curiousintrovert
Thank you for joining us for our 2nd Cabral HouseCall of the weekend! I'm looking forward to sharing with you some of our community's questions that have come in over the past few weeks… Shannon: I am curious what your take on headaches that stem in your neck and the base of the skull called cervicogenic headaches. What's the root cause of that type of muscle tension headache? I've struggled with them for a couple years now. I'm working with a practitioner and have tested for candida and am on the CBO protocol currently. We're getting ready to test for hormone imbalances next week but I'm fairly sure I have Imbalances. I have heavy cycles and low iron as well with the headaches being mainly the first weekish of the cycle. Jason: Hello Dr. Cabral, I've dealt with tonsil stones and hemmrhoids for quite some time. I know I have sibo, dysbiosis, and some yeast/fungal overgrowth. Working on those as well. Wondering if you can explain why these are happening and what I can do for them apart from the CBO. Thanks! Emily: My MIL has high levels of Lipoprotien(a) 232. Her LDL levels are in a good range. She is currenly taking the statin Crestor which is hydrophilic. The RYR is a more natural form but seems to be a lipophilic statin. Her worry is that lipophilic statins crosses the blood brain barrier. Could you please explain this and if this should be of great concern? Would it be better for someone to take a hydrophilic statin vs RYR? Dana: Asked this on the Facebook page and was advised to ask here. My husband and I are currently doing CBO protocol. Before starting that my husband started getting unusually exhausted after moderate exercise, 50 years old and has always been active, no known health issues. Moderate activity now wipes him out for the rest of the day, this is unusual for him. Recently went to PCP who did blood work and found ALP levels over 450, tested again to rule out lab error and it was about 10 points higher. Has had heart ultrasound and stress test, both normal. Will be getting abdominal ultrasound next week to check liver, etc. If ok, probably bones next. Wondering if CBO protocol dieoff could contribute to high ALP? Live in a country where we can't do mail lab testing. Advice on what else to check for? Brent: Hi Dr. Cabral, I ran labs years ago and was recommended the cbo with C drops and finisher. Labs showed no parasites at that time. During the cbo i started to see some progress in my digestion and other areas but once I started month 3 I started to notice acid reflux symptoms like a swollen throat and shortness of breath that worsened at night. (symptoms I've had for many years that returned). I thought it was because of changes to my gut microbiome and continued on to the cbo finisher and the problems only got worse to the point that I had to stop the protocols. I can only assume that somewhere along the line due to stress or poor food combining or not eating strict enough that I ended up causing sibo while trying to fix it. Can't think of any other reasons for my situation. Plz help ty. Thank you for tuning into this weekend's Cabral HouseCalls and be sure to check back tomorrow for our Mindset & Motivation Monday show to get your week started off right! - - - Show Notes and Resources: StephenCabral.com/3803 - - - Get a FREE Copy of Dr. Cabral's Book: The Rain Barrel Effect - - - Join the Community & Get Your Questions Answered: CabralSupportGroup.com - - - Dr. Cabral's Most Popular At-Home Lab Tests: > Complete Minerals & Metals Test (Test for mineral imbalances & heavy metal toxicity) - - - > Complete Candida, Metabolic & Vitamins Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Complete Stress, Mood & Metabolism Test (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Complete Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Complete Omega-3 & Inflammation Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels) - - - Get Your Question Answered On An Upcoming HouseCall: StephenCabral.com/askcabral - - - Would You Take 30 Seconds To Rate & Review The Cabral Concept? The best way to help me spread our mission of true natural health is to pass on the good word, and I read and appreciate every review!
On today's Good Day Health Show - ON DEMAND…Dr. Jack Stockwell, a NUCCA Chiropractor and GAPS Practitioner in SLC, UT (866.867.5070 | ForbiddenDoctor.com | JackStockwell.com), shares a holistic perspective on health news today. Dr. Jack offers an insightful discussion challenging common beliefs about cholesterol, aging, and the role nutrition plays in maintaining long-term health. Dr. Jack examines widespread misconceptions surrounding cholesterol, explaining why it is an essential component of the body and discussing research suggesting that excessively low cholesterol levels—particularly in older adults—may be associated with certain health risks. The conversation explores the relationship between cholesterol and healthy aging, while encouraging listeners to better understand cholesterol's many functions beyond cardiovascular health.The episode also takes a closer look at the growing use of GLP-1 weight-loss medications, including Ozempic, and discusses concerns about their potential impact on connective tissue, muscle mass, and overall body composition during significant weight loss. Dr. Jack emphasizes the importance of supporting connective tissue through proper nutrition, adequate protein intake, essential nutrients, and healthy lifestyle habits that promote strength, mobility, and resilience as we age.Throughout the discussion, Doug and Dr. Jack examine how nutrition, inflammation, and lifestyle choices influence the aging process and overall wellness. They also explore the role the medical industry has played in shaping public perceptions of cholesterol and heart health, encouraging listeners to consider a broader perspective when evaluating their own health decisions. The episode concludes with practical strategies for supporting connective tissue health naturally, providing listeners with actionable insights for maintaining strength, mobility, and overall well-being throughout every stage of life.For more on Good Day Health…Website: GoodDayHealthShow.comSocial Media: @GoodDayNetworks
As part of our summer series, we're revisiting some of the most important conversations we've had on the topics that matter most to our health. And few are more important than heart disease. Heart disease remains the number one cause of death worldwide. Yet despite decades of research, millions of prescriptions, and billions of dollars spent on treatment, many people are still confused about what actually causes it—and what we can do to prevent it. For years, the conversation around heart disease has focused almost entirely on cholesterol. But what if that's only part of the story? In this special compilation episode, you'll hear from Dr. Cindy Geyer of The UltraWellness Center, Dr. Eric Topol, and Dr. Aseem Malhotra as they explore a different perspective on heart disease—one that goes beyond cholesterol and looks at the deeper drivers of cardiovascular risk, including inflammation, insulin resistance, metabolic dysfunction, lifestyle, and early detection. You'll hear why many experts now believe heart disease often begins decades before symptoms appear, why traditional testing can miss important warning signs, and how emerging science is giving us new tools to identify risk earlier than ever before. Most importantly, you'll hear a message that is both practical and hopeful: that many of the factors driving heart disease are within our control, and that prevention remains one of the most powerful tools we have. Let's dive in. View Show Notes From This Episode Sign up for Dr. Hyman's Brainshaping Academy to learn how to nourish the biological systems that support your mental, emotional, and cognitive health https://drhyman.com/products/brainshaping?utm_source=dr_hyman_show&utm_medium=newsletter&utm_campaign=may_27&utm_content=link Get Free Weekly Health Tips from Dr. Hyman https://drhyman.com/pages/picks?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Sign Up for Dr. Hyman's Weekly Longevity Journal https://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Join the 10-Day Detox to Reset Your Health https://drhyman.com/pages/10-day-detox Join the Hyman Hive for Expert Support and Real Results https://drhyman.com/pages/hyman-hive This episode is brought to you by BON CHARGE, BIOptimizers, Rho, Made In, Seatopia, and Cozy Earth. Explore red light products at boncharge.com/hyman and enjoy 15% off with code HYMAN. Go to bioptimizers.com/hyman and use code HYMAN to save 15% off your order, plus get a free gift. Explore science-backed products at rhonutrition.com and use code HYMAN for 20% off the entire site. Upgrade your cookware at madeincookware.com and save 10% off your first order with code HYMAN-HIVE. Find a cleaner source of seafood. Check out seatopia.fish/hyman and receive free shipping on your first order. Head to cozyearth.com to save 20% and upgrade all of your daily essentials today. (0:00) The persistence of heart disease and the low-fat diet hypothesis (0:32) Preventing heart disease through diet, lifestyle, and simple behaviors (2:19) Revisiting key conversations on heart disease (3:44) Beyond cholesterol: deeper drivers and risk factors (7:18) Typical workup, treatments, and advances in cholesterol testing (17:48) Metabolic health, hormonal, and inflammatory factors in heart disease (29:37) Advances in cardiovascular diagnostics and AI (31:31) Impact of lifestyle and new pharmacological treatments (36:55) Statins, side effects, and lipoprotein fractionation (40:13) The role of AI, new diagnostics, and Dr. Topol's journey (43:19) Rethinking treatment: diet, industry influence, and the low-fat craze (45:28) Saturated fat, cholesterol, and revisiting the evidence (48:00) Cholesterol in heart disease risk and systematic drug review (52:31) Insulin resistance, cholesterol's role, and mortality (58:31) Challenges in changing medical dogma (1:00:31) Closing remarks and call to action
What standard GP testing misses, and why it matters more for athletes. Several months ago I wrote a LinkedIn post about my own decision to start taking statins, after several years of resisting that path. Katherine Caris-Harris, a performance nutritionist and fellow triathlete, reached out afterwards. She felt there were gaps in the conversation, and she was right. Katherine is a degree-qualified nutritionist who works with what she calls corporate athletes, driven, high-performing people who often push themselves too hard across every area of life. In this episode we dig into the limitations of standard GP cholesterol testing, why LDL alone is a poor predictor of cardiovascular risk, the role of insulin resistance and thyroid function in driving cholesterol up, what the actual numbers needed to treat for statins really look like, and why cholesterol itself is essential, not the villain it's often made out to be. This isn't an anti-medication conversation. Katherine isn't here to tell you what to do. It's about giving you the fuller picture so you can make an informed decision for yourself, whatever that ends up being. 5 KEY POINTS LDL alone is a poor predictor of risk. Standard GP testing estimates LDL using a crude calculation, and doesn't account for particle size or how easily those particles are damaged by inflammation. Better markers exist, but aren't routinely offered. ApoB and Lipoprotein(a) give a far more accurate picture of cardiovascular risk than standard LDL testing, but most GPs don't test for them due to cost. The number needed to treat varies hugely. For primary prevention in a low risk group, you may need to treat 100 to 200 people with statins to prevent one cardiovascular event. That context rarely makes it into the conversation. Insulin resistance can quietly drive cholesterol up. Even lean, fit endurance athletes can develop elevated blood sugar and insulin resistance through excessive use of gels, energy drinks and fasted training. Cholesterol is essential, not the enemy. It's required for hormone production, cell repair, brain health and vitamin D synthesis. The real driver of arterial damage is oxidative stress and inflammation. 3 TAKEAWAYS Get tested properly before deciding. Standard GP panels are a useful starting point but rarely tell the full story, particularly for athletes. Context matters more than a single number. Genetics, insulin resistance, thyroid function and inflammation all contribute to your real cardiovascular risk. Make your decision from a position of knowledge, not fear. Whatever you choose to do, do it with the fuller picture in front of you. KILLER QUOTE "You wouldn't ignore your FTP test results. So why would you ignore what's actually happening under the hood with your cardiovascular health?" CONNECT with Katherine Katherine Caris-Harris is a performance and functional nutritionist working with driven, high-performing clients juggling demanding careers with serious training. She is also a long-time age-group triathlete.
A free guide to FSM training is available there for licensed practitioners. https://frequencyspecific.com/how-to-choose-your-fsm-core-training Hosts: Carolyn McMain, MA, DC & Kim Pittis, LCSP, (PHYS), MT In this episode of the Frequency Specific Microcurrent (FSM) podcast, Dr. Carol and Kim Pittis discuss the importance of treating the whole patient—not just the injury—and strongly discourage using AI or published frequency lists to create FSM protocols, emphasizing hands-on assessment and clinical reasoning. They troubleshoot an ACL post-op case with patellar tendinopathy and quad inhibition, highlighting tissue-based detective work (especially the fat pad, scarring, nerves, and cartilage) and noting that effective frequencies should produce palpable softening quickly. They also explain how to differentiate disc versus facet referral patterns in the upper back based on flexion/extension provocation, recommend considering flexion-extension X-rays and hypermobility screening for chronic neck issues, address questions on statin-related neuropathy and antidepressant tapering, share carpal tunnel strategies and outcomes, and explore vagus-focused approaches for interoception, pelvic pain, coccydynia, and vaginismus. They close with course announcements and a reminder that AI cannot diagnose, treat, or provide reliable legal documents. 00:00 Healing Beyond Tissue 00:38 FSM Podcast Intro 01:05 OR Teamwork Mindset 03:01 Perioperative Care Gaps 04:53 AI Protocol PSA 08:02 ACL Rehab Case Study 13:25 Hands-On Over Algorithms 16:02 Tendonitis vs Tendinopathy 18:25 Neck Pain Disc vs Facet 24:34 Reading Imaging Like a Pro 29:12 Trust the Exam 29:43 Statins and Antidepressants 32:13 Carpal Tunnel Protocols 35:48 Interoception and Vagus 37:52 Pelvic Pain and Dura 41:44 Arachnoid and Simplifying FSM 43:45 Radiation Scar Case 45:15 Vaginismus Treatment Options 48:01 Athlete Anxiety and Safety 51:01 AI Limits and Connection 52:45 Course Dates and Wrap Up 55:08 Podcast Disclaimer
In this week's episode the Powell men discuss sick care in the U.S. Our #heathcare sucks. Doctors prescribe medicines and then prescribe medicines to treat the symptoms/side efrects of the medicines they prescribed. #Statins , #bloodpressurepills , and #glp oh my! The guys also discuss the #earthquake in #Venezuela . The #MayorofNYC #ZohranMamdani stays winning . The #DemocraticSocialistsofAmerica are winning. #NBATrades #Knicks #SecondApron #JamesDolan
What if the surgery that fixed your knee did no better than fake surgery? EconTalk host Russ Roberts speaks with Dr. John Mandrola about a striking clinical trial in which patients who received sham knee surgery (a real incision, but no actual repair) did as well or better than those who had the actual procedure--one performed 700,000 times annually in the U.S. The conversation ranges from the power of placebo and nocebo effects (how expectation of harm can cause real suffering) to the broader philosophy of "medical conservatism"--the idea that humility, watchful waiting, and honest counsel often serve patients better than the knife. Mandrola argues that financial incentives, professional identity, and language itself ("bone-on-bone," "the widowmaker") conspire to push patients toward interventions that can do more harm than good.
Listener feedback on valvular heart disease, statins and frailty, left atrial posterior wall ablation fails again, interpreting medical tests and AI ECG reading are the topics John Mandrola, MD, discusses in this week's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I Listener Feedback PREVUE-VALVE Study https://www.jacc.org/doi/10.1016/j.jacc.2026.02.5137 II Statins and Frailty Statin Initiation Tied to Lower Frailty Risk in Older Adults https://www.medscape.com/viewarticle/statin-initiation-tied-lower-frailty-risk-older-adults-2026a1000lec Statins and Survival Free of Incident Frailty https://doi.org/10.1093/eurheartj/ehag451 III LA Posterior Wall Isolation Fails Again CORNERSTONE Trial https://doi.org/10.1093/eurheartj/ehag486 CAPLA Trial https://jamanetwork.com/journals/jama/fullarticle/2800186 IV Does the Display of Test Results Improve Clinical Decisions? Interval Likelihood Ratios for Clinical Decsion-Making https://evidence.nejm.org/doi/full/10.1056/EVIDoa2500249 Making Sense of Health Statistics https://journals.sagepub.com/doi/full/10.1111/j.1539-6053.2008.00033.x V AI and the ECG and Saving Doctors Case Report — AI-Enhanced Diagnostics https://www.nature.com/articles/s41591-026-04454-y The New York Times article https://www.nytimes.com/2026/06/22/health/artificial-intelligence-heart-damage.html You may also like: The Bob Harrington Show with the Stephen and Suzanne Weiss Dean of Weill Cornell Medicine, Robert A. Harrington, MD. https://www.medscape.com/author/bob-harrington Questions or feedback, please contact news@medscape.net
He carried two copies of ApoE4, the highest genetic risk factor for Alzheimer's disease, went through medical school knowing exactly what his LDL of 700 meant, decided the experts were wrong, and then published the case report to prove it. In this episode, Louisa sits down with Dr. Nick Norwitz, PhD researcher and metabolic scientist, for one of the most scientifically dense conversations on brain health, cholesterol biology, and Alzheimer's prevention ever recorded on this show. They cover why the phospholipid form of DHA reaches the brain more effectively than standard fish oil, how ApoE4 carriers burn through omega-3s differently and what to do about it, the lithium orotate data that sold out supplement shelves worldwide, and why GSK-3 beta, the enzyme that phosphorylates tau, may be the most under appreciated target in Alzheimer's research today. Then Dr. Nick Norwitz lays out the case that challenges the "LDL is always the enemy" consensus: why metabolically healthy individuals may not benefit from aggressive lipid-lowering therapy, what his viral coronary CT angiogram showed after seven years of 700+ cholesterol, why the EZPAVE trial headlines don't hold up under scrutiny, and what GLP-1s are doing inside the brain completely independent of weight loss. You'll also hear about the sardine diet experiment, the omega-3 thermogenesis connection, ketones as misfolded protein clearance agents, creatine for depression, retatrutide and PCSK9, BPC-157 risks, and what Dr. Nick Norwitz believes is coming in Alzheimer's gene therapy within the next decade. *Reduce your risk of Alzheimer's with my science-backed protocol for women 30+:*https://go.neuroathletics.com.au/youtube-sales-page Subscribe to The Neuro Experience for evidence-based conversations at the intersection of brain science, longevity, and performance. _____ *TOPICS DISCUSSED*(00:00:00) Intro: The ApoE4 Paradox and the Case Report That Broke the Internet (00:00:57) Why Standard Omega-3 Supplements Fail and What to Take Instead (00:05:13) DHA and the Phospholipid Carrier: How It Crosses the Blood-Brain Barrier (00:10:19) ApoE4 Explained: Risk, Genetics, and Why Nick Is Optimistic (00:17:38) Why ApoE4 Carriers Burn Through DHA Faster and Need More (00:20:31) Women, Omega-3s, Menopause, and Brain Insulin Resistance (00:21:41) Statins, Sex Differences, and the DHA-Blood Sugar Connection (00:26:01) Statins and Dementia: What the Data Actually Say (00:32:24) Tau, GSK-3 Beta, Lithium Orotate, and Targeting Alzheimer's Pathology (00:42:19) The Glymphatic System, 40Hz Devices, and Sleep as Brain Clearance (00:45:21) Gene Editing, Prime Editing, and the Future of ApoE4 Therapy (00:49:33) Nick's Case Report: 700 LDL, Zero Plaque, and Seven Years of Data (00:55:10) The EZPAVE Trial: Why the Headlines Don't Hold Up (01:00:33) KetoneIQ: Ketones for Brain Energy and Focus (01:01:29) Cheers Health: Supporting Liver Function and Cognitive Recovery (01:03:54) If Not LDL, What Causes Heart Disease in Metabolically Healthy People? (01:12:05) The Oreo Experiment and the Sardine Diet: Self-Experiments in Metabolism (01:19:10) Ketones, Women's Brains, and Clearing Misfolded Proteins (01:21:08) The Full Brain Health Protocol: Omega-3s, Creatine, NAD, Lithium, and More (01:24:01) GLP-1s for the Brain: Independent of Weight, Targeting Amyloid and Tau (01:25:28) Peptides: BPC-157 Risks, Retatrutide, MOTS-c, and What's Worth Watching (01:29:02) Why Nick Is Controversial And Why He Doesn't Mind _______ *Thank you to our sponsors*Fenix Health Science: fenixhealthscience.com Use code NEUROEXPPulsetto: https://pulsetto.tech/pages/NEURO or use Code NEURO for some off your orderFunction Health: https://www.functionhealth.com/louisanicolaBASED Bodyworks: https://basedbodyworks.com/ and use code NEURO for 20% offKetoneIQ: https://ketone.com/NEURO for 30% OFFCheers Health: https://CheersHealth.com/NEURO or use code NEURO for 20% off _______ I'm Louisa Nicola - clinical neurophysiologist - Alzheimer's prevention specialist - founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention.If you're committed to optimizing your brain- reducing Alzheimer's risk - and staying mentally sharp for life, you're in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0Instagram: https://www.instagram.com/louisanicola_/Twitter : https://twitter.com/louisanicola_ Learn more about your ad choices. Visit megaphone.fm/adchoices
He carried two copies of ApoE4, the highest genetic risk factor for Alzheimer's disease, went through medical school knowing exactly what his LDL of 700 meant, decided the experts were wrong, and then published the case report to prove it. In this episode, Louisa sits down with Dr. Nick Norwitz, PhD researcher and metabolic scientist, for one of the most scientifically dense conversations on brain health, cholesterol biology, and Alzheimer's prevention ever recorded on this show. They cover why the phospholipid form of DHA reaches the brain more effectively than standard fish oil, how ApoE4 carriers burn through omega-3s differently and what to do about it, the lithium orotate data that sold out supplement shelves worldwide, and why GSK-3 beta, the enzyme that phosphorylates tau, may be the most under appreciated target in Alzheimer's research today. Then Nick lays out the case that challenges the "LDL is always the enemy" consensus: why metabolically healthy individuals may not benefit from aggressive lipid-lowering therapy, what his viral coronary CT angiogram showed after seven years of 700+ cholesterol, why the EZPAVE trial headlines don't hold up under scrutiny, and what GLP-1s are doing inside the brain completely independent of weight loss. You'll also hear about the sardine diet experiment, the omega-3 thermogenesis connection, ketones as misfolded protein clearance agents, creatine for depression, retatrutide and PCSK9, BPC-157 risks, and what Nick believes is coming in Alzheimer's gene therapy within the next decade. Reduce your risk of Alzheimer's with my science-backed protocol for women 30+:https://go.neuroathletics.com.au/youtube-sales-page Subscribe to The Neuro Experience for evidence-based conversations at the intersection of brain science, longevity, and performance. _____ TOPICS DISCUSSED 00:00 Intro: The ApoE4 Paradox and the Case Report That Broke the Internet 00:57 Why Standard Omega-3 Supplements Fail and What to Take Instead 05:13 DHA and the Phospholipid Carrier: How It Crosses the Blood-Brain Barrier 10:19 ApoE4 Explained: Risk, Genetics, and Why Nick Is Optimistic 17:38 Why ApoE4 Carriers Burn Through DHA Faster and Need More 20:31 Women, Omega-3s, Menopause, and Brain Insulin Resistance 21:41 Statins, Sex Differences, and the DHA-Blood Sugar Connection 26:01 Statins and Dementia: What the Data Actually Say 32:24 Tau, GSK-3 Beta, Lithium Orotate, and Targeting Alzheimer's Pathology 42:19 The Glymphatic System, 40Hz Devices, and Sleep as Brain Clearance 45:21 Gene Editing, Prime Editing, and the Future of ApoE4 Therapy 49:33 Nick's Case Report: 700 LDL, Zero Plaque, and Seven Years of Data 55:10 The EZPAVE Trial: Why the Headlines Don't Hold Up 01:00:33 KetoneIQ: Ketones for Brain Energy and Focus 01:01:29 Cheers Health: Supporting Liver Function and Cognitive Recovery 01:03:54 If Not LDL, What Causes Heart Disease in Metabolically Healthy People? 01:12:05 The Oreo Experiment and the Sardine Diet: Self-Experiments in Metabolism 01:19:10 Ketones, Women's Brains, and Clearing Misfolded Proteins 01:21:08 The Full Brain Health Protocol: Omega-3s, Creatine, NAD, Lithium, and More 01:24:01 GLP-1s for the Brain: Independent of Weight, Targeting Amyloid and Tau 01:25:28 Peptides: BPC-157 Risks, Retatrutide, MOTS-c, and What's Worth Watching 01:29:02 Why Nick Is Controversial And Why He Doesn't Mind _______ Thank you to our sponsors Fenix Health Science: fenixhealthscience.com Use code NEUROEXP Pulsetto: https://pulsetto.tech/pages/NEURO or use Code NEURO for some off your order Function Health: https://www.functionhealth.com/louisanicola BASED Bodyworks: https://basedbodyworks.com/ and use code NEURO for 20% off KetoneIQ: https://ketone.com/NEURO for 30% OFF Cheers Health: https://CheersHealth.com/NEURO or use code NEURO for 20% off _______ I'm Louisa Nicola - clinical neurophysiologist - Alzheimer's prevention specialist - founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain- reducing Alzheimer's risk - and staying mentally sharp for life, you're in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Learn more about your ad choices. Visit megaphone.fm/adchoices
For those of us with high cholesterol, there are two options: changing your diet,…
What if one of the most important health crises affecting men today wasn't being caused by aging, but by the environment we live in? In this eye-opening solo episode, Darin Olien investigates the alarming decline in testosterone levels, fertility, and reproductive health among men worldwide. Drawing on decades of research, epidemiological studies, environmental science, endocrinology, and public health data, Darin examines the growing evidence connecting endocrine-disrupting chemicals, microplastics, sleep deprivation, chronic stress, poor lifestyle habits, and environmental toxins to declining testosterone levels across generations. From BPA, phthalates, atrazine, PFAS, and microplastics to sleep quality, circadian rhythms, cholesterol metabolism, cortisol regulation, and natural testosterone-supporting strategies, this episode explores what may be one of the most underreported public health issues of our time—and what men can do to take control of their health today. What You'll Learn Why testosterone levels have been declining for decades The startling research on global sperm count decline How endocrine-disrupting chemicals interfere with hormone production Why BPA and phthalates may disrupt testosterone synthesis The role of atrazine, PFAS, and environmental toxins How chronic stress diverts resources away from testosterone production Why sleep may be the most important testosterone intervention The connection between cholesterol and hormone production How microplastics are being found throughout the human body The surprising relationship between statins and testosterone levels Natural lifestyle strategies that support healthy hormone production Practical steps to reduce environmental exposure and improve health Chapters 00:00:00 – Welcome to SuperLife 00:00:33 – Sponsor: Fatty15 and cellular health 00:04:17 – The testosterone collapse explained 00:04:51 – Testosterone levels have been declining for decades 00:06:03 – Global sperm count decline and accelerating trends 00:07:02 – Why treating symptoms misses the root cause 00:07:27 – The hidden public health crisis 00:08:03 – Why low testosterone isn't just about aging 00:09:12 – Why hormone health affects longevity 00:09:53 – Low testosterone and increased mortality risk 00:10:35 – Testosterone's role in metabolism and cardiovascular health 00:11:27 – Endocrine-disrupting chemicals and hormone disruption 00:12:44 – BPA and its effects on testosterone production 00:13:59 – Phthalates and their impact on hormone pathways 00:16:00 – Glyphosate, atrazine, and pesticide exposure 00:17:07 – PFAS and reproductive health concerns 00:17:55 – Environmental toxins and population-wide effects 00:18:11 – Sponsor: Shakeology 00:20:02 – Cholesterol and hormone production 00:20:53 – Chronic stress and cortisol dominance 00:21:45 – Actionable solutions begin 00:21:56 – Why sleep is essential for testosterone production 00:23:07 – How sleep deprivation rapidly lowers testosterone 00:23:21 – Light pollution and circadian disruption 00:23:41 – Foods and nutrients needed for hormone health 00:24:23 – Microplastics and testicular tissue 00:24:53 – Statins and unintended hormonal consequences 00:25:39 – A practical testosterone sovereignty protocol 00:25:48 – Water filtration and reducing toxic exposure 00:26:13 – Eliminating plastics and fragrance chemicals 00:26:35 – Why organic food matters 00:26:45 – Sunlight and vitamin D 00:27:05 – Magnesium, omega-3s, and iodine 00:27:26 – Pine pollen and natural androgen support 00:28:01 – Tongkat Ali and ashwagandha 00:28:48 – Strength training and lifestyle interventions 00:29:10 – Habits that naturally support testosterone 00:29:27 – Darin's approach to healthy aging 00:29:37 – Plants, herbs, and common sense 00:29:51 – Reclaiming your health and sovereignty 00:30:00 – Final thoughts and closing message Thank You to Our Sponsors Fatty15: Get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com/DARIN and using code DARIN at checkout. Shakeology: Get 15% off with code DARINO1BODI at Shakeology.com. Join the SuperLife Patreon: This is where Darin now shares the deeper work: - weekly voice notes - ingredient trackers - wellness challenges - extended conversations - community accountability - sovereignty practices Join now for only $7.49/month at https://patreon.com/darinolien Find More from Darin Olien: Website: darinolien.com Instagram: @darinolien Book: Fatal Conveniences Platform & Products: superlife.com New Show: Roadmap to Happiness Key Takeaway "The testosterone crisis may be about far more than aging. It may be a reflection of the modern environment itself—one increasingly saturated with endocrine-disrupting chemicals, chronic stress, poor sleep, circadian disruption, and toxic exposures. While many of these forces feel outside our control, the encouraging reality is that many of the most powerful interventions remain accessible: improving sleep, reducing toxic load, eating whole foods, getting sunlight, managing stress, exercising regularly, and reclaiming responsibility for our health. The goal isn't fear. The goal is awareness—and action." Bibliography/Sources: The Decline — Primary Research Levine, H., Jørgensen, N., Martino-Andrade, A., et al. (2022). Temporal trends in sperm count: A systematic review and meta-regression analysis of samples collected globally in the 20th and 21st centuries. Human Reproduction Update, 29(2), 157–176. https://doi.org/10.1093/humupd/dmac035 Lokeshwar, S. D., Patel, P., Fantus, R. J., et al. (2021). Decline in testosterone levels in men aged 15–40: Results from the National Health and Nutrition Examination Survey (NHANES), 1999–2016. World Journal of Urology, 39(2), 447–452. https://doi.org/10.1007/s00345-020-03227-1 Spital Clinic. (2026, March). Declining testosterone levels by generation. https://www.spitalclinic.com Travison, T. G., Araujo, A. B., O'Donnell, A. B., Kupelian, V., & McKinlay, J. B. (2007). A population-level decline in serum testosterone levels in American men. The Journal of Clinical Endocrinology & Metabolism, 92(1), 196–202. https://doi.org/10.1210/jc.2006-1375 Low Testosterone — Mortality & Disease Risk Muraleedharan, V., Marsh, H., Kapoor, D., Channer, K. S., & Jones, T. H. (2013). Testosterone deficiency is associated with increased risk of mortality and testosterone replacement improves survival in men with type 2 diabetes. European Journal of Endocrinology, 169(6), 725–733. https://doi.org/10.1530/EJE-13-0321 Shores, M. M., et al. (2006). Low testosterone associated with increased all-cause and cardiovascular mortality. Archives of Internal Medicine, 166(15), 1660–1665. https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/410754 Yeap, B. B., Marriott, R. J., Dwivedi, G., et al. (2024). Associations of testosterone and related hormones with all-cause and cardiovascular mortality and incident cardiovascular disease in men. Annals of Internal Medicine. https://doi.org/10.7326/M23-2781 Endocrine Disrupting Chemicals Associations between endocrine-disrupting chemical exposure and fertility outcomes: A decade of human epidemiological evidence. (2024). PubMed Central (PMC12299029). https://pmc.ncbi.nlm.nih.gov/articles/PMC12299029/ Hayes, T. B., Haston, K., Tsui, M., et al. (2002). Herbicides: Feminization of male frogs in the wild. Nature, 419, 895–896. https://doi.org/10.1038/419895a Mechanisms of testicular disruption from exposure to BPA and phthalates. (2020). Journal of Clinical Medicine, 9(2), 471. https://pmc.ncbi.nlm.nih.gov/articles/PMC7074154/ Meeker, J. D., Calafat, A. M., & Hauser, R. (2014). Urinary phthalate metabolites and their biotransformation products: Predictors and temporal variability among men and women. Journal of Exposure Science & Environmental Epidemiology. https://www.sciencedaily.com/releases/2014/08/140814124330.htm Zhao, Q., et al. (2023). Male reproductive toxicity of microplastics: Head and tail of the sperm. Science of the Total Environment, 872, 162181. https://doi.org/10.1016/j.scitotenv.2023.162181 Zhong, B., et al. (2024). Mixed EDC exposure associated with reductions in testosterone and free androgen index. Scientific Reports. https://doi.org/10.1038/s41598-024-76972-z Cortisol, Stress & the HPG Axis Bielohuby, M., et al. (2012). Swiss military cadets prolonged stress study. Psychoneuroendocrinology. Preprints.org. (2025). Sleep deprivation: A modifiable cause. https://doi.org/10.20944/preprints202505.0580.v1 SiPhox Health. (n.d.). Summary of Journal of Clinical Endocrinology & Metabolism data. https://www.siphoxhealth.com Viau, V. (2002). Functional cross-talk between the hypothalamic-pituitary-gonadal and -adrenal axes. Journal of Neuroendocrinology, 14(6), 506–513. https://doi.org/10.1046/j.1365-2826.2002.00798.x Sleep & Testosterone Leproult, R., & Van Cauter, E. (2011). Effect of 1 week of sleep restriction on testosterone levels in young healthy men. JAMA, 305(21), 2173–2174. https://jamanetwork.com/journals/jama/fullarticle/1029127 Reiter, R. J., et al. (2021). Melatonin and male reproductive health: Relationship to oxidative stress, mitochondrial function, and Leydig cell protection. Endocrine. Tan, D. X., Hardeland, R., Manchester, L. C., et al. (2023). Melatonin as a pleiotropic antioxidant hormone. Journal of Pineal Research. Nutrition — Zinc, Vitamin D, Cholesterol Corona, G., et al. (2010). Statin therapy and testosterone levels in men: A systematic review. The Journal of Sexual Medicine. Daniell, H. W. (2002). Hypogonadism in men consuming sustained-action oral opioids. The Journal of Pain, 3(5), 377–384. https://doi.org/10.1054/jpai.2002.126790 Pilz, S., Frisch, S., Koertke, H., et al. (2011). Effect of vitamin D supplementation on testosterone levels in men. Hormone and Metabolic Research, 43(3), 223–225. https://doi.org/10.1055/s-0030-1269854 Prasad, A. S., Mantzoros, C. S., Beck, F. W., Hess, J. W., & Brewer, G. J. (1996). Zinc status and serum testosterone levels of healthy adults. Nutrition, 12(5), 344–348. https://doi.org/10.1016/S0899-9007(96)80058-X Natural Testosterone Support — Botanical Evidence Pine pollen impacts testosterone-related symptoms in men. (2024). ACMCR Case Reports, 14(5), 1–9. Chinnappan, S. M., George, A., et al. (2021). Effect of Eurycoma longifolia standardised extract Physta on testosterone levels in ageing males: A randomised, double-blind, placebo-controlled multicentre study. Food & Nutrition Research, 65. https://doi.org/10.29219/fnr.v65.5647 Lazarev, A., & Bezuglov, E. (2021). Testosterone boosters intake in athletes: Current evidence and further directions. Endocrines, 2(2), 109–120. https://doi.org/10.3390/endocrines2020011 Leisegang, K., et al. (2022). Eurycoma longifolia (Tongkat Ali) improves serum total testosterone in men. Food & Nutrition Research. https://pubmed.ncbi.nlm.nih.gov/36013514/ Leitão, A. E., et al. (2021). 6-month double-blind RCT: Eurycoma longifolia 200mg + concurrent training. Maturitas. https://doi.org/10.1016/j.maturitas.2020.10.005 Lopresti, A. L., Smith, S. J., et al. (2019). An investigation into the stress-relieving and pharmacological actions of an ashwagandha extract. Medicine, 98(37), e17186. https://doi.org/10.1097/MD.0000000000017186 Pandit, S., Biswas, S., Jana, U., De, R. K., Mukhopadhyay, S. C., & Biswas, T. K. (2016). Clinical evaluation of purified shilajit on testosterone levels in healthy volunteers. Andrologia, 48(5), 570–575. https://doi.org/10.1111/and.12482 Saden-Krehula, M., Tajic, M., & Kolbah, D. (1971). Testosterone, epitestosterone and androstenedione in the pollen of Scotch pine Pinus sylvestris L. Experientia, 27(1), 108–109. https://doi.org/10.1007/BF02137731 Wankhede, S., Langade, D., Joshi, K., et al. (2015). Examining the effect of Withania somnifera supplementation on muscle strength and recovery: A randomized controlled trial. Journal of the International Society of Sports Nutrition, 12, 43. https://doi.org/10.1186/s12970-015-0104-9
Is LDL really the “bad cholesterol”? Uncover the truth behind common cholesterol myths, what high LDL and cholesterol levels actually mean, and whether elevated LDL is as dangerous as you've been led to believe.0:00 Is LDL bad?0:20 LDL cholesterol explained 2:00 Two types of LDL cholesterol2:37 Advanced lipid profile test3:57 Cholesterol research6:39 Cholesterol and heart disease prevention10:52 Clogged arteries and LDL10:28 Large-buoyant LDL vs. small-dense LDL 11:48 Statins 13:07 High cholesterol levels in healthy people
Free course: Improve your metabolic healthGet our free email course on how glucose, nutrition, exercise, sleep, and measurement can help you build habits that support better energy and long-term health: https://levels.link/wnlHigh cholesterol. Elevated ApoB. A positive CAC score. Now what?Most people quickly find themselves trapped between two extremes: simplistic advice to “cut saturated fat” and online influencers insisting cholesterol doesn't matter at all.In this episode of A Whole New Level, Mike Haney sits down with clinical research scientist Dr. Kevin Maki to cut through the confusion.Drawing on more than 35 years of cardiovascular research, Maki explains why heart disease risk is about much more than LDL cholesterol alone. He breaks down the roles of inflammation, blood sugar, family history, kidney function, and lipoproteins, while also making a clear case for something many people resist: LDL and ApoB still matter. A lot.The evidence increasingly suggests that when it comes to atherosclerosis, lower for longer is better. That has important implications for diet, statins, and how early we should intervene.Mike and Dr. Maki also tackle saturated fat, seed oils, red meat, industry-funded research, and how to separate evidence from online nutrition debates.
The Real Truth About Health Free 17 Day Live Online Conference Podcast
John Abramson, M.D. explains how patients can use 'number needed to treat' (NNT) and risk thresholds to make informed, values-driven decisions about statin use. #InformedConsent #StatinRisks #PatientEmpowerment #HealthTalks
In this episode, preventive cardiologist Dr. Ann Marie Navar, a member of the committee that helped shape the American Heart Association's new recommendations for earlier cholesterol management, explains why many experts believe cardiovascular prevention should begin decades before most people ever experience symptoms. Dr. Navar explains why lowering LDL cholesterol earlier in life can have lasting benefits decades later, how ApoB and lipoprotein(a) are reshaping the way experts think about heart disease risk, and why some of the most popular fears surrounding statins aren't supported by the evidence. The conversation also explores the growing divide between evidence-based medicine and the wellness industry and the challenges of separating compelling biological theories from treatments that have actually been proven to improve health outcomes. She's a wealth of knowledge and a wonderful guest. Hope you enjoy.
This week, Marianna sits down with John Faragon to talk about the latest updates to HIV diagnoses, deaths, and prevalence, along with new information on statin use for people with HIV.-- Help us track the number of listeners our episode gets by filling out this brief form! (https://www.e2NECA.org/?r=AQX7941)--Want to chat? Email us at podcast@necaaetc.org with comments or ideas for new episodes. --Check out our free online courses: www.necaaetc.org/rise-courses--Download our HIV mobile apps:Google Play Store: https://play.google.com/store/apps/developer?id=John+Faragon&hl=en_US&gl=US Apple App Store: https://apps.apple.com/us/developer/virologyed-consultants-llc/id1216837691
View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter Tom Dayspring is a world-renowned lipidologist and one of the most thoughtful teachers in the field of lipid metabolism. In this episode, Tom returns to The Drive for a deep dive into the relationship between lipids and brain health, beginning with the fundamentals of cholesterol transport before exploring why the brain's cholesterol system operates almost entirely independently from the rest of the body. Tom examines the roles of apoB, apoA-I, and especially apoE in cholesterol homeostasis, discusses how APOE genotype influences Alzheimer's disease risk, and unpacks the complex links between cholesterol metabolism, amyloid, and tau pathology. He also reviews what is currently known—and still uncertain—about the effects of statins, ezetimibe, omega-3 fatty acids, and emerging CETP inhibitors on brain health and neurodegenerative disease risk. Although highly technical, this conversation provides an essential framework for understanding the nuanced relationship between lipid-lowering therapies, cardiovascular disease prevention, and neurodegenerative diseases in an area often clouded by misinformation. We discuss: The fundamentals of cholesterol transport in the body, and how peripheral cholesterol metabolism differs from cholesterol handling in the brain [2:45]; How cholesterol is transported through plasma and stored within cells, and why lowering LDL cholesterol does not deplete the body or brain of cholesterol [11:45]; How apoB particles drive atherosclerosis, why lowering lipids matters, and the factors that influence individual cardiovascular risk [20:00]; How the brain produces and transports its own cholesterol using apoE lipoproteins independently of circulating cholesterol and apoB-containing lipoproteins [29:00]; How apoB structure influences LDL receptor binding and LDL clearance [39:00]; How neurons acquire cholesterol from apoE-containing lipoproteins and why desmosterol serves as a unique marker of cholesterol synthesis in the brain [41:45]; The difference between the APOE gene and the apoE protein, the major APOE genotypes found in humans, and how APOE4 influences Alzheimer's disease risk [48:45]; HDL function beyond cholesterol: immune function, protein cargo, and communication with the brain [53:30]; How APOE4-associated defects in brain cholesterol transport may promote Alzheimer's disease: amyloid production, neuronal cholesterol homeostasis, and cholesterol clearance [58:00]; Statins and brain health: reviewing the evidence of the potential impact of statins on cognition and Alzheimer's disease risk [1:09:00]; Desmosterol and 24S-hydroxycholesterol as biomarkers of brain cholesterol metabolism and statin effects [1:17:15]; Possible cognitive benefits of ezetimibe beyond lowering apoB [1:19:30]; EPA, DHA, and the evidence for omega-3 fatty acids in brain health [1:23:15]; Obicetrapib: an emerging CETP inhibitor with potential implications for both cardiovascular and brain health [1:31:00]; and More. Connect With Peter on Twitter, Instagram, Facebook and YouTube
The “Enhanced Games”, with no-holds-barred performance-enhancing drugs, yields scant advantages over “clean” contests; Does saturated fat increase insulin resistance? Can a heart attack victim avoid statin use with CoQ10? Omega-3 fish oil shows promise vs. type 2 diabetes; Motorized e-scooter use needs to be regulated NOW!
If you've ever left a doctor's appointment thinking, "That answered exactly none of my questions," this episode is for you. This week, I'm joined by fellow physician assistant and functional medicine practitioner Shelly Satizabal for a candid conversation about perimenopause, hormone replacement therapy (HRT), birth control, statins, medical gaslighting, and women's health. We discuss why so many women are told they're "too young" for perimenopause, why symptoms get dismissed despite "normal" labs, and how women continue to fall through the cracks of a healthcare system that historically wasn't designed around female physiology. We also dive into hormones, cholesterol, statins, women's health research, and why asking questions shouldn't make you a difficult patient. If you've ever felt unheard, brushed off, or like nobody is interested in finding the root cause of your symptoms, this conversation is for you. Learn more about working with me Shop my masterclasses (learn more in 60-90 minutes than years of dr appointments) Follow me on IG Follow Empowered Mind + Body on IG Learn More About Shelly here Follow Shelly on IG
Heart Disease Prevention: The Complete Cardiologist's Guide to Statins & Early Detection 700,000 Americans die from heart disease every year but most of these deaths are PREVENTABLE. In this groundbreaking episode, Dr. McConnell from Stanford reveals how to treat your heart like cancer: with early detection, proper treatment, and personalized prevention strategies that actually save lives.
Show Notes HOST Melody Hartzler | | Book Appointment AROUND THE TABLE Joel Kahn | | Visit Website In Today's Episode Preventive cardiologist Dr. Joel Kahn joins Melody Hartzler on this episode of Table Talk to break down how lifestyle changes, nutrition, and advanced diagnostic testing can protect your heart. Dr. Kahn shares his journey from traditional interventional cardiology to preventive care and explains how inflammation, diet, hormone changes, and personalized risk assessments can help identify cardiovascular issues before they become serious. Key Take Aways Heart disease prevention starts with understanding individual risk factors, including inflammation, family history, metabolic health, and lifestyle habits. Advanced testing such as coronary artery calcium scans, carotid ultrasounds, and inflammatory markers can provide a more complete picture of cardiovascular risk. Whole-food, plant-based nutrition remains one of the most powerful tools for preventing and even reversing heart disease. Lipoprotein(a) is an often-overlooked genetic risk factor that can significantly impact cardiovascular health, especially in women. Lifestyle changes—including nutrition, exercise, stress management, sleep, and weight management—should be the foundation of any heart health plan before considering more aggressive interventions. Topics Discussed 00:00 – Welcome to Table Talk Melody Hartzler introduces today's guest, preventive cardiologist Dr. Joel Kahn, and previews the discussion on heart disease prevention and functional medicine. 01:06 – Dr. Kahn's Journey to Preventive Cardiology Dr. Kahn shares how his experience in traditional cardiology led him to focus on preventing heart disease through lifestyle and nutrition. 03:00 – The Impact of Plant-Based Nutrition How nutrition transformed Dr. Kahn's approach to patient care and cardiovascular health. 04:15 – A Common Patient Scenario Discussing women approaching menopause and the cardiovascular changes that often emerge during this stage of life. 05:27 – Looking Beyond Standard Labs The importance of comprehensive cardiovascular assessments, lifestyle factors, and personalized risk evaluation. 06:00 – Understanding Inflammation and Heart Disease Key inflammatory markers and why inflammation plays a central role in cardiovascular health. 07:24 – Omega-3 Testing and Nutritional Strategies How omega-3 levels and targeted nutrition can support heart health and reduce risk. 07:41 – Measuring Arterial Health Using carotid ultrasounds and artery age assessments to detect cardiovascular issues early. 08:39 – Coronary Artery Calcium Scans Explained Who should consider a calcium scan and how it helps identify hidden heart disease risk. 09:51 – Interpreting Calcium Scores What different calcium scores mean and when intervention may be necessary. 11:37 – Advanced Cardiovascular Testing Exploring inflammatory markers, metabolic indicators, and additional tools for risk assessment. 12:38 – The Importance of Lipoprotein(a) Understanding this genetic risk factor and its role in cardiovascular disease. 14:00 – Supplements for Heart Health A discussion on red yeast rice, omega-3s, berberine, and other commonly used supplements. 15:31 – Niacin and Cholesterol Management When niacin may be helpful and how it fits into a cardiovascular prevention plan. 17:02 – Choosing Quality Supplements What to look for when selecting supplements and why quality matters. 19:00 – Red Yeast Rice vs. Statins Comparing natural and pharmaceutical approaches to cholesterol management. 20:00 – Statins, Side Effects, and CoQ10 Addressing common concerns and discussing strategies to support patients using statins. 24:00 – Is a Plant-Based Diet Necessary? Dr. Kahn shares his perspective on nutrition and individualized approaches to heart health. 26:00 – AGEs and Cooking Methods How advanced glycation end products affect cardiovascular health and practical ways to reduce exposure. 27:49 – Resources and Where to Find Dr. Kahn Dr. Kahn shares where listeners can learn more about his work and access additional resources. 28:18 – Final Thoughts and Closing Remarks Key takeaways from the conversation and a wrap-up of the episode. Resources Mentioned Table Talk Podcast — Resources & Links The PharmToTable Team – Functional Medicine Providers Therapies & Approaches Discussed: Preventive Cardiology Functional Medicine Plant-Based Nutrition Lifestyle Medicine Inflammation Reduction Hormone Replacement Therapy (HRT) Tests & Biomarkers Discussed: Coronary Artery Calcium (CAC) Scan Carotid Artery Ultrasound Lipoprotein(a) [Lp(a)] High-Sensitivity C-Reactive Protein (hs-CRP) Omega-3 Testing Supplements Discussed: Berberine Niacin (Vitamin B3) Endur-Acin® CoQ10 (Coenzyme Q10) Supplement Spotlight Vitamin D / K2 Liquid - 1 fl oz Purchase Today D3 5000 with K2 60 Softgels Purchase Today
Nutritionist Leyla Muedin discusses research showing simple strength tests—grip strength and a five-rep sit-to-stand chair test—predict longevity in older women. In a University at Buffalo study of over 5,000 women ages 63–99 followed for eight years, stronger grip and faster chair-stand times were linked to lower mortality; every additional 7 kg of grip strength corresponded to a 12% reduction in death risk, and faster chair-stands were also associated with improved survival, even after adjusting for activity, cardiovascular fitness, and inflammation. She emphasizes prioritizing muscle-strengthening alongside aerobic exercise and suggests accessible resistance options (weights, bodyweight moves, or household items) with professional guidance as needed. She then cites UK Biobank data linking long-term statin use to declines in grip strength and appendicular lean mass, urging discussion with physicians and added vigilance, especially for those also using GLP-1 drugs that may reduce protein intake and muscle mass.
“All good scientists are skeptics.” — Dr. Anthony Pearson Key Links The Skeptical Cardiologist on Substack is HERE American Heart Association 2026 Guidelines is HERE MESA CAC Database is HERE In this episode, I'm joined by Dr. Anthony Pearson, the cardiologist behind The Skeptical Cardiologist newsletter on Substack, for a practical conversation about what women over 50 need to know now about heart health. We talk about the new cholesterol guidelines, why personalized risk assessment matters, and why tests like CAC, Lp(a), and ApoB can reveal much more than a standard lipid panel alone. What You Will Learn: Why heart disease is still the number one killer of women The biggest blind spots women over 50 still have about heart risk What changed in the new cholesterol guidelines Why earlier detection and more personalized risk assessment matter Why CAC, Lp(a), and ApoB are getting more attention What those tests can reveal that a standard lipid panel may miss Why statins still matter, despite all the noise around them When non-statin options may make sense The role of inflammation in cardiovascular disease The lifestyle habits that still matter most for prevention A few key takeaways from this conversation You can feel healthy, exercise regularly, eat well, and still have hidden cardiovascular risk A standard cholesterol panel does not always tell the full story CAC, Lp(a), and ApoB can help create a more complete and individualized picture of risk High Lp(a) is inherited and is important to know about, even before a specific drug is widely available ApoB is a more precise marker of atherogenic particles and can add valuable information to routine testing Statins remain an important, well-studied first-line tool for many people Prevention works best when you start earlier, not after a cardiac event Cardio exercise, strength training, and maintaining a healthy body composition all matter Subscribe to AGE BETTER so you never miss an episode!
Episode 2805 - Vinnie Tortorich and Anna Vocino discuss a cholesterol conundrum regarding CAC scores, numbers, and how to naturally balance those numbers. https://vinnietortorich.com/2026/05/a-cholesterol-conundrum-episode-2805 PLEASE SUPPORT OUR SPONSORS Pure Vitamin Club Pure Coffee Club NSNG® Foods VILLA CAPPELLI EAT HAPPY KITCHEN YOU CAN WATCH THIS EPISODE ON YOUTUBE - @FitnessConfidential Podcast Vinnie's workout videos are available to purchase! Choose from a 2-day, 4-day, or 6-day workout–or buy all three at a discount! TO PURCHASE VINNIE'S WORKOUT VIDEOS, CLICK THIS LINK: https://vinnietortorich.com/workout A Cholesterol Conundrum Vinnie recently posted on social media about the Women's Health Initiative. (3:00) The problem with Google is that you can "Google yourself right," so you can always find confirmation bias. There is a growing awareness of what constitutes a "clean" product. (17:00) For example, Anna's spices do not have fillers, preservatives, or anti-caking agents. Vinnie shares a story about a recent consultation. (28:00) CAC scans (calcium score test) are a great guide to see if heart disease will be an issue for you. Repatha was recommended even though the patient's numbers were great, and his calcium score was zero. Consider exploring natural supplements and lifestyle changes to manage cholesterol. The Cholesterol Code movie by Dave Feldman provides good information on cholesterol levels and the benefits of a low-carb diet. Anna goes over some bloodwork numbers and wants to discuss with her doctor. (50:00) Remember that the number ranges given in the results are representative of the general population. (52:00) It is often recommended to take CoQ10 alongside a statin. Statins deplete CoQ10, which can lead to muscle damage. Anna's products are now linked to PureVitamin Club's website. Look under the "Food and Snacks" section so that you can purchase them there, too. (58:30) https://purevitaminclub.com/collections/food-and-snacks The NSNG® VIP GROUP IS NOW CLOSED AGAIN AS OF SUNDAY, MARCH 15TH Anna's next cookbook, Eat Happy Cocktail Hour, is filled with cocktails, mocktails, and appetizers and is available for pre-order right now. If you pre-order, you'll get bonus goodies! You can preorder from a wide variety of booksellers at https://eathappycocktailhour.com/ Save your receipt from wherever you preorder, you'll need it for your bonuses! Physical Release Date is October 2026 A New Sponsor Jaspr Air Scrubbers has a discount code, VINNIE, that gets you $200 off for a limited time. Jaspr offers a lifetime warranty. Go to Jaspr.co for more information or to purchase. (1:05:00) You can book a consultation with Vinnie to get guidance on your goals. https://vinnietortorich.com/phone-consultation-2/ More News Serena has added some of her clothing suggestions and beauty product suggestions to Vinnie's Amazon Recommended Products link. Self Care, Beauty, and Grooming Products that Actually Work! https://www.amazon.com/shop/vinnietortorich/list/3GPVU29UHHPMY?ref_=aipsflist Don't forget to check out Serena Scott Thomas on Days of Our Lives on the Peacock channel. "Dirty Keto" is available on Amazon! You can purchase or rent it here.https://amzn.to/4d9agj1 Please make sure to watch, rate, and review it! Eat Happy Italian, Anna's second cookbook, is available! You can go to https://eathappyitalian.com You can order it from Vinnie's Book Club. https://amzn.to/3ucIXm Anna's recipes are in her cookbooks, on her website, and on Substack —they will spice up your day! https://annavocino.substack.com/ PURCHASE DIRTY KETO (2024) The documentary launched in August 2024! Order it TODAY! This is Vinnie's fourth documentary in just over five years. Visit my new Documentaries HQ to find my films everywhere: https://vinnietortorich.com/documentaries Then, please share my fact-based, health-focused documentary series with your friends and family. Additionally, the more views it receives, the better it ranks, so please watch it again with a new friend! REVIEWS: Please submit your REVIEW after you watch my films. Your positive REVIEW does matter! PURCHASE BEYOND IMPOSSIBLE (2022) Visit my new Documentaries HQ to find my films everywhere: https://vinnietortorich.com/documentaries FAT: A DOCUMENTARY 2 (2021) Visit my new Documentaries HQ to find my films everywhere: https://vinnietortorich.com/documentaries FAT: A DOCUMENTARY (2019) Visit my new Documentaries HQ to find my films everywhere: https://vinnietortorich.com/documentaries
Adam talks with American journalist Patrick Radden Keefe about his book London Falling: A Mysterious Death in a Gilded City and a Family's Search for Truth, the challenges presented by parenting adolescents, the seductive power of movies like The Wolf Of Wall Street and Patrick's own efforts to resist the glamorising effect of TV and film during production of the TV adaptation of his book about the Troubles in Northern Ireland, Say Nothing, and Adam's own ludicrous taste of the criminal life in his early adolescence. There's also chat about why David Byrne's live show was the best live music show Adam has ever seen and whether it's OK to stand up at a seated music show.Conversation recorded face-to-face in Bath on 7 May, 2026LONDON FALLING by Patrick Radden Keefe - 2026 (Waterstones)CLARIFICATION RE. STATINS vs GLP-1sResponding to Adam's comments about statins at the end of the conversation with Patrick, this was sent in by Dr Mit Shah, MBBS BSc (Hons) PhD, Consultant Cardiologist in Preventive Cardiology, Harefield Hospital:I'm a consultant cardiologist specialising in lipid disorders and preventive cardiology. While both GLP-1 drugs and statins can reduce cardiovascular risk, they work through very different mechanisms and treat different underlying problems. Statins are specifically used to lower LDL cholesterol, whereas GLP-1 drugs mainly work through the blood glucose and weight-loss pathway, with only modest effects on cholesterol.Statins have become somewhat unfairly maligned through widespread misinformation and exaggerated claims about side effects, despite very strong clinical evidence for benefit. In fact, researchers have even performed randomised trials demonstrating a significant “nocebo effect”, where patients experience expected side effects even when taking placebo tablets due to their preconceived expectations and worries. Daily, I see patients with severe (sometimes genetic) cholesterol disorders who have a critical need for statin therapy, but who are understandably hesitant because of what they've heard online. I worry that the idea that GLP-1s could simply replace statins may unintentionally add to that confusion.SUBMIT QUESTIONS FOR Q&A EPISODE: Adambuxtonpodcast@gmail.comThanks to Diggory Waite and Claire Broughton at Hattrick and Séamus Murphy Mitchell for production support.Podcast illustration by Helen GreenSPONSOR: SAILY
On this vintage episode of Vitality Radio, Jared takes a hard look at the cholesterol hypothesis and why it has failed to deliver true solutions for heart health. Instead of focusing on lowering cholesterol—a vital compound for hormones, brain function, and cellular integrity—he highlights the often-overlooked root cause: stiff, aging arteries. You'll learn how the blood vessels lose flexibility with age, stress, toxins, poor diet, and inactivity, and why this breakdown leads to high blood pressure and drives cardiovascular risk far more than cholesterol numbers alone. Jared explains the role of nitric oxide in reversing arterial aging and how natural boosters like beets, leafy greens, and amino acids support healthy nitric oxide production. This episode is about shifting the conversation: instead of suppressing what the body needs, learn how to encourage its own built-in repair and resilience mechanisms.Products:N.O. Cardio BoostVital D3/K2Ultimate Vitality MultiNutraBio Beet Root PowderSolaray Beet Root CapsulesNutraBio L-Citrulline PowderBlack Market Labs L-Citrulline PowderJust Ingredients Pre-Workout Visit the podcast website here: VitalityRadio.comYou can follow @vitalitynutritionbountiful and @vitalityradio on Instagram, or Vitality Radio and Vitality Nutrition on Facebook. Join us also in the Vitality Radio Podcast Listener Community on Facebook. Shop the products that Jared mentions at vitalitynutrition.com. Let us know your thoughts about this episode using the hashtag #vitalityradio and please rate and review us on Apple Podcasts. Thank you!Just a reminder that this podcast is for educational purposes only. The FDA has not evaluated the podcast. The information is not intended to diagnose, treat, cure, or prevent any disease. The advice given is not intended to replace the advice of your medical professional.
For decades, a tight carotid stenosis felt like a ticking time bomb — a plaque waiting to throw an embolus and cause the next stroke. We were taught that severe narrowing meant surgery, and trials like ACAS and ACST-1 seemed to prove it. But medicine has changed. Statins, antiplatelets, tighter blood pressure control, even PCSK9 and GLP-1 therapies have quietly slashed stroke risk, and now newer data from CREST-2 suggest that for many asymptomatic patients, the knife — or the stent — may not add much at all. So if modern medical therapy works better than ever… who actually benefits from intervention anymore? Today, we unpack the evidence, the controversies, and how to counsel the patient who feels perfectly fine but has high-grade stenosis.Hosts: Carolyn Judge, Andrew Huang, Luciano Delbono, Frank Davis, Robert BeaulieuInstitution: University of Michigan, Department of Surgery, Section of Vascular SurgeryLearning objectives: Describe how modern intensive medical therapy has transformed the natural history of asymptomatic carotid stenosis and explain why contemporary patients experience substantially lower annual stroke risk than those in earlier eras. Interpret and compare the results of landmark trials—including ACAS, ACST-1, and CREST-2—to assess the relative benefits of medical therapy, endarterectomy, and stenting. Apply current evidence and guideline recommendations to patient care by selecting which asymptomatic patients are most likely to benefit from carotid revascularization versus optimized medical therapy alone. References:SVS Guidelines:Brook, R. D., et al. (2022). Society for Vascular Surgery clinical practice guidelines for management of extracranial carotid artery disease. Journal of Vascular Surgery, 75(1), e1–e67. https://doi.org/10.1016/j.jvs.2021.09.031CREST (1)Brott, T. G., Hobson, R. W., Howard, G., et al. (2010). Stenting versus endarterectomy for treatment of carotid-artery stenosis. New England Journal of Medicine, 363(1), 11–23. https://doi.org/10.1056/NEJMoa0912321CREST-2Brott, T. G., Howard, G., Fong, P., et al. (2024). Randomized trial of carotid artery stenting or carotid endarterectomy vs best medical therapy for asymptomatic carotid stenosis: CREST-2 results. [Manuscript in preparation]. ClinicalTrials.gov Identifier: NCT02089217. Retrieved from https://clinicaltrials.gov/ct2/show/NCT02089217ACST-1Halliday, A., Mansfield, A., Marro, J., et al. (2004). Randomised trial of carotid artery surgery for asymptomatic stenosis. Lancet, 363(9420), 1491–1502. https://doi.org/10.1016/S0140-6736(04)16153-1ACST-2Halliday, A., Bulbulia, R., Bonati, L. H., et al. (2021). Carotid artery stenting versus carotid endarterectomy in patients with asymptomatic carotid stenosis (ACST-2): A randomised trial. Lancet, 398(10291), 1065–1073. https://doi.org/10.1016/S0140-6736(21)01980-1ACASExecutive Committee for the Asymptomatic Carotid Atherosclerosis Study. (1995). Endarterectomy for asymptomatic carotid stenosis. JAMA, 273(18), 1421–1428. https://doi.org/10.1001/jama.1995.03520420033036Sponsor URL: https://www.goremedical.com/Please visit https://behindtheknife.org to access other high-yield surgical education podcasts, videos and more. If you liked this episode, check out our recent episodes here: https://behindtheknife.org/listenBehind the Knife Premium: https://behindtheknife.org/premiumOral Board Review: https://behindtheknife.org/oral-boardOral Board Simulator: https://behindtheknife.org/oral-board/simulatorGeneral Surgery Oral Board Review Course: https://behindtheknife.org/premium/general-surgery-oral-board-reviewTrauma Surgery Video Atlas: https://behindtheknife.org/premium/trauma-surgery-video-atlasDominate Surgery: A High-Yield Guide to Your Surgery Clerkship: https://behindtheknife.org/premium/dominate-surgery-a-high-yield-guide-to-your-surgery-clerkshipDominate Surgery for APPs: A High-Yield Guide to Your Surgery Rotation: https://behindtheknife.org/premium/dominate-surgery-for-apps-a-high-yield-guide-to-your-surgery-rotationVascular Surgery Oral Board Review Course: https://behindtheknife.org/premium/vascular-surgery-oral-board-audio-reviewColorectal Surgery Oral Board Review Course: https://behindtheknife.org/premium/colorectal-surgery-oral-board-audio-reviewSurgical Oncology Oral Board Review Course: https://behindtheknife.org/premium/surgical-oncology-oral-board-audio-reviewCardiothoracic Oral Board Review Course: https://behindtheknife.org/premium/cardiothoracic-surgery-oral-board-audio-reviewDownload our App:Apple App Store: https://apps.apple.com/us/app/behind-the-knife/id1672420049Android/Google Play: https://play.google.com/store/apps/details?id=com.btk.app&hl=en_US
Which is the safest and most effective?
Why aren't they prescribed for everyone?