Podcasts about Gastroenterology

Send us Fan MailCrohn's disease and ulcerative colitis already feel complicated, but when IBD shows up in a baby or a preschooler, the rules can change fast. We're joined by Dr. Scott B. Snapper, a leader in pediatric and adult IBD research from Boston Children's Hospital, to unpack very early onset IBD (VEO-IBD) and why some of these cases are driven by single-gene immune disorders rather than the “usual” mix of risks we talk about in inflammatory bowel disease.We get into how Dr. Snapper's work with immune deficiency and mouse models helped reveal clear cause-and-effect pathways, and why that matters for real treatment choices. If a child has IL-10 receptor deficiency, standard IBD medications like anti-TNF therapy may not work, and bone marrow transplant can be curative. We also talk about what happens when transplant isn't possible right away, including the promise of targeted options like IL-1 blockade, and why certain immune defects respond to very specific therapies. Along the way, we zoom out to the big goal in IBD care: fewer rounds of trial and error, more precision medicine guided by biomarkers from blood, stool, and biopsies.We also dig into whole exome sequencing, insurance realities, and the ethics of genetic information, including the very real fear of future discrimination. Finally, Scott shares how the VEO-IBD Consortium grew into a global resource for clinicians and families through veoibd.org, and why he's genuinely optimistic about the future of IBD therapy, including better tools for pain and gut-brain symptoms.Subscribe for more real talk about IBD, share this with someone who needs hope, and please leave a rating and review so more patients and caregivers can find the show.VEO-IBD ConsortiumDr. Snapper won the Sherman Prize last yearVEO-IBD Information from Boston Children's HospitalVEO-IBD Information from the Crohn's & Colitis Foundation- USALet's get social!!Follow us on Instagram!Follow us on Facebook!Follow us on Twitter!

On this episode of Vitality Radio, Jared continues his series on the intelligence of symptoms with a look at nausea, vomiting, diarrhea, and heartburn. These uncomfortable digestive symptoms may feel like the body is malfunctioning, but in many cases they are part of the body's natural protective response. Jared explains why nausea can act as an early warning, how vomiting and diarrhea help the body remove unwanted substances, and why simply shutting these responses down may not always be the best approach. He also discusses activated charcoal, ginger, probiotics, digestive enzymes, and supportive strategies for digestive distress. Finally, Jared explores acid reflux, the important role of stomach acid, concerns surrounding long-term PPI use, and why supporting healthy digestive function may offer a better long-term strategy.Additional Information:***Watch for all 4 parts of this series on Symptoms!Visit the podcast website here: VitalityRadio.comYou can follow @vitalitynutritionbountiful and @vitalityradio on Instagram, or Vitality Radio and Vitality Nutrition on Facebook. Join us also in the Vitality Radio Podcast Listener Community on Facebook. Shop the products that Jared mentions at vitalitynutrition.com. Let us know your thoughts about this episode using the hashtag #vitalityradio and please rate and review us on Apple Podcasts. Thank you!Just a reminder that this podcast is for educational purposes only. The FDA has not evaluated the podcast. The information is not intended to diagnose, treat, cure, or prevent any disease. The advice given is not intended to replace the advice of your medical professional.

In this episode of Bowel Sounds, hosts Dr. Peter Lu and Dr. Jenn Lee talk to Dr. A. Jay Freeman, pediatric gastroenterologist at Nationwide Children's Hospital and Professor at The Ohio State University College of Medicine.  He is a leading clinician and researcher in pediatric pancreatic disorders and the GI and liver complications of cystic fibrosis. He provides a massive update on the treatment of cystic fibrosis, including the changing clinical landscape with the advent and use of CFTR modulator therapies.Dr. Freeman does not have any conflicts of interest to disclose.Learning objectivesDescribe key GI and liver manifestations of cystic fibrosisExplain how CFTR modulatos have changed GI and Liver disease in children with cystic fibrosis.Apply current screening and management strategies for GI complications in children with cystic fibrosisSend us Fan MailSupport the showThis episode may be eligible for CME credit!  Once you have listened to the episode, click this link to claim your credit.  Credit is available to NASPGHAN members (if you are not a member, you should probably sign up).  And thank you to the NASPGHAN Professional Education Committee for their review!As always, the discussion, views, and recommendations in this podcast are the sole responsibility of the hosts and guests and are subject to change over time with advances in the field.Check out our merch website!Follow us on Bluesky, Twitter, Facebook and Instagram for all the latest news and upcoming episodes.Click here to support the show.

In this special crossover episode, Tuesday Night IBS co-founder Jeffrey Roberts, MSEd, BSc, is joined by William D. Chey, MD, Lin Chang, MD, Kate Scarlata, MPH, RDN, LDN, and Amanda Lynett, MS, RDN, at the FOOD is the Main Course conference. ·       How did you manage the diet paradigm shift for managing care in GI conditions? 2:28 ·       How did witnessing the use of multidisciplinary treatment teams change your clinical practice? 15:05 ·       What was it like to manage the unique emotional toll in your career without burning out?  26:13 ·       What advice do you have for residents and fellows in GI? 43:36 ·       What core values do you hope others have learned from your leadership roles? 58:06 We'd love to hear from you! Send your comments/questions to guttalkpodcast@healio.com. Follow us on X @HealioGastro, @sameerkberry and @umfoodoc. For more Tuesday Night IBS, be sure check out TuesdayNightIBS.com and to follow and subscribe to their podcast.   References: ·       Drossman DA. Gastroenterology. 2001;doi:10.1053/gast.2001.28976. ·       Khan S, et al. Nat Rev Gastroenterol Hepatol. 2010;doi:10.1038/nrgastro.2010.137.   Chang reports consulting for Ardelyx, Atmo, Eli Lilly & Co., FoodMarble, GSK, Ironwood Pharmaceuticals and Ono Pharmaceutical; receiving speaking fees from Bausch Health; receiving research grants from AnX Robotica and Ironwood; serving on the Rome Foundation board of directors; and having unvested stock options with FoodMarble, ModifyHealth, PICO Health and Trellus Health. Scarlata reports having stock options with Verve Market, Epicured LLC and Fody Foods and receiving financial support from Ardelyx, Salix pharmaceuticals, Orgain and Activia. Chey, Lynett and Roberts report no relevant financial disclosures.   Chang is professor of medicine and vice chief of the Vatche & Tamar Manoukian Division of Digestive Diseases at David Geffen School of Medicine at UCLA. Lynett is the lead registered dietitian with the division of gastroenterology and hepatology at the University of Michigan and co-director of the Food The Main Course conference. Roberts is a patient advocate and creator of the first website for IBS sufferers. He is the co-founder of Tuesday Night IBS. Scarlata is a U.S.-based dietitian with over 30 years of experience. Her expertise is in gastrointestinal disorders and food intolerance.

Nirmala Gonsalves, MD, discusses findings from the landmark DEGAS trial evaluating dupilumab in eosinophilic gastritis (EOG). She explores the evolving understanding of Type 2 inflammation, transcriptomic remodeling and the clinical implications of the trial results for gastroenterologists.

Send us Fan MailWatching your partner lose their health in real time changes everything and it can happen faster than most people realize. We're joined by Andrea and Dusty Sibley, who take us from the confusion of early symptoms and ER misdiagnoses to a full colectomy, ostomy life, and the J-pouch surgery path that finally got Dusty back to living the life he wants. Along the way, we talk about the weird moments that stick with you, like being told you “look like you're dying” when you're actually healing, or having to use a motorized grocery cart in your 40s because your body simply can't do more yet.Andrea shares what doesn't get asked often enough: what it's like to be the caregiver. We dig into the vows you don't think about until you're living them, the nurse-patient dynamic that can take over a marriage, parenting during long hospital stays, and the quiet trauma that caregivers carry while telling themselves they shouldn't feel that way. Dusty opens up about one of the scariest parts of his hospitalization: blood transfusions, why they felt terrifying at first, and how they became a turning point when his energy and color finally came back.Their story also explains why they started No Guts All Glory, a nonprofit supporting people with Crohn's disease, ulcerative colitis, and colon cancer through care packages for the hospital-to-home transition, plus kid-friendly ostomy bears and books that help families talk about what's happening. If you're searching for real talk on IBD, ostomy surgery, J-pouch recovery, colonoscopy fears, and invisible illness, this conversation brings both the hard truth and the hope. Subscribe, share, and leave a review, then tell us what part of their journey hit closest to home.Links: No Guts All Glory websiteNo Guts All Glory: Stories of Strength podcast- SpotifyNo Guts All Glory InstagramLet's get social!!Follow us on Instagram!Follow us on Facebook!Follow us on Twitter!

Episode 55 Luba Plotkin - Tasty & Healthy Diet for Pediatric Crohn's Disease In this episode of Nutrition Pearls: the Podcast, co-hosts Jen Smith and Nikki Misner speak with Luba Plotkin on Tasty&Healthy, a whole foods diet for Crohn's Disease. Luba Plotkin is the project manager for Tasty&Healthy. She is a Research Dietitian at the Juliet Keidan Institute of Pediatric Gastroenterology and Nutrition, Shaare Zedek Medical Center in Jerusalem. Luba is a Ph.D. Candidate in Nutritional Science and Biochemistry at the Hebrew University of Jerusalem, and Vice President of the Israeli Dietetic Association. Nutrition Pearls is supported by an educational grant from Mead Johnson Nutrition.Resources:Aharoni-Frutkoff Y, Plotkin L, Pollak D, et al. Whole Food Diet Induces Remission in Children and Young Adults With Mild to Moderate Crohn's Disease and Is More Tolerable Than Exclusive Enteral Nutrition: A Randomized Controlled Trial. Gastroenterology. 2025;169(7):1462-1474.e2. doi:10.1053/j.gastro.2025.06.011 Plotkin L, Aharoni-Frutkoff Y, Pollak D, et al. Tasty&Healthy Exclusive Whole-Food Diet in Asymptomatic Children and Young Adults With Biologically Active Crohn's Disease: The TASTI-E Randomized Controlled Trial. Clin Gastroenterol Hepatol. Published online June 17, 2026. doi:10.1016/j.cgh.2026.05.029https://tasty-healthy.comTasty and Healthy: Eating Well with Lactose Intolerance, Coeliac Disease, Crohn's disease, Ulcerative Colitis and Irritable Bowel SyndromeProduced by: Corey IrwinNASPGHAN - Council for Pediatric Nutrition Professionalscpnp@naspghan.org

Marking 350 episodes, Dr. Scott Watier breaks down seven research-backed physiological changes that happen in the body at just 5-10% weight loss, arguing that the "magic" everyone chases at their big goal weight is actually front-loaded far earlier than most people realize. Pulling from journals like Cell Metabolism, Gastroenterology, and Diabetes Care, he walks through the data: a 5% drop in body weight is tied to a 16% reduction in visceral fat and a 24% reduction in liver fat with muscle essentially untouched, a 4-5 point drop in blood pressure, a 38% cut in overnight sleep apnea events, and a 3.5x greater likelihood of a meaningful A1C improvement in diabetics. He makes the case that this is a measurement problem, not a discipline problem — people quit chasing a distant "big number" instead of tracking the waist measurement, blood pressure, or A1C changes already happening under the surface — and ties fasting specifically to defending lean muscle mass while compressing the eating window drives these results. The episode closes with concrete action steps: calculate your own 5% and 10% targets, pick one metric to track instead of just the scale, keep your last bite before 6pm per the earlier Dr. Courtney Peterson research, prioritize protein at every meal, and write down three non-scale outcomes to watch for before the scale rewards you! Take the NEW FASTING PERSONA QUIZ! - The Key to Unlocking Sustainable Weight Loss With Fasting!⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Resources and Downloads: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠***NEW RESOURCE!*** GRAB THE INSULIN RESISTANCE BUCKETS SUMMARY GUIDE⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠SIGN UP FOR THE DROP OF THE ULTIMATE GUIDE TO BLOOD SUGAR CONTROL⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠GRAB THE OPTIMAL RANGES FOR LAB WORK HERE! - NEW RESOURCE! ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠FREE RESOURCE - DOWNLOAD THE NEW BLUEPRINT TO FASTING FOR FAT LOSS!⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠SLEEP GUIDE DIRECT DOWNLOAD⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠DOWNLOAD THE FASTING TRANSFORMATION JOURNAL HERE!⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Partner Links: Get your⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ FREE BOX OF LMNT⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ hydration support for the perfect electrolyte balance for your fasting lifestyle with your first purchase⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ here!⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Get ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠25% off a Keto-Mojo⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ blood glucose and ketone monitor (discount shown at checkout)! ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Click here!⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Our Community: Let's continue the conversation. Click the link below to JOIN the ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Fasting For Life Community⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠, a group of like-minded, new, and experienced fasters! The first two rules of fasting need not apply! If you enjoy the podcast, please tap the stars below and consider leaving a short review on Apple Podcasts/iTunes. It takes less than 60 seconds, and it helps bring you the best original content each week. We also enjoy reading them! Article Link:

Commonly people are talking about "peptides" to refer to a heterogeneous group of peptide medications or investigational compounds. These are increasingly promoted for injury recovery, tissue repair, performance and longevity, with BPC-157 attracting particular attention. But what evidence supports the claims made about these compounds? How should animal studies, biological mechanisms and personal anecdotes be interpreted? What is currently known about their safety? And what do recent regulatory discussions actually mean for their medical status and availability? In this episode, physician and Barbell Medicine founder Dr. Jordan Feigenbaum examines the evidence surrounding BPC-157 and other peptide medications, alongside the wider questions of risk, access and informed decision-making. Timestamps [00:13] What we want to address [04:47] Interview start [05:29] What do we mean by "peptides"? [10:32] BPC-157 evidence [16:49] Sourcing of peptides [20:19] The gray zone of pro-peptide communication [24:16] Risk sourcing vs drug effects [26:25] FDA lists and compounding [31:05] Risk tolerance and informed consent [43:02] Why did pharma abandon peptide research? [47:44] Harm reduction debate [51:48] Practical takeaways [56:20] Key Ideas segment (Premium members only) Episode Resources Go to episode page  Join the Sigma newsletter for free Subscribe to Sigma Nutrition Premium Enroll in the next cohort of our Applied Nutrition Literacy course Barbell Medicine Instagram: jordan_barbellmedicine Book: Signal: What Testosterone Levels Are Telling You About Your Health Related episode: #524: Strength & Fitness Levels for Reducing Chronic Disease Risk & Promoting Health Ageing – Jordan Feigenbaum, MD Further reading: Emerging use of BPC-157 in orthopaedic sports medicine: a systematic review. 2025. Ruenzi M, Stolte M, Veljaca M, et al. Efficacy and safety of PL 14736 (BPC 157) in patients with active ulcerative colitis. Gastroenterology. 2005. Meeting abstract; full study not published.

Menopause timing is not purely genetic — and this episode explains how to delay menopause by supporting the systems that actually set the clock. Nurse Doza covers the three estrogens you make across a lifetime (E1, E2, E3), why estradiol supports your heart, cholesterol, and insulin, how PCOS and inflamed fat cells drive estrone production, and which labs to order and when in your cycle to run them. You will also hear why the liver belongs in every hormone conversation. FEATURED PRODUCT Liver Boost (Detox) by MSW Nutrition — $111 Your liver is where estrogen gets processed, conjugated, and cleared — which is why this episode keeps circling back to it. Liver Boost (formerly known as Liver Love) is a comprehensive formula designed to support phase I and phase II liver detoxification of environmental toxins, the same two-phase pathway your body uses to handle hormones. When that pathway is working against processed food, alcohol, and years of medication, everything downstream of it gets harder. Nurse Doza takes it daily alongside Mitochondriac (NAD+ Support) — $119 — a complete bioflavonoid complex with resveratrol, quercetin, and pterostilbene. That pairing is what he names at the close of this episode: support the liver, support the mitochondria.

Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Dr Muyiwa Awoniyi, who is an Clinical Staff Transplant Hepatologist and Assistant Professor from the Department of Gastroenterology, Hepatology and Nutrition, Digestive Disease Institute, Hepatology Section, Department of Inflammation and Immunity, Cleveland Clinic Research Institute in Cleveland, Ohio, USA, on the paper "Dysbiotic microbiota trigger colitis-associated colorectal cancer and imprint a distinctive bile acid profile in a PSC-IBD model" published in paper copy in Gut in September 2026. Please subscribe to the Gut podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/3UOTwqS) or Spotify (https://bit.ly/4rRJeUI).

MASH is often called a silent disease, but its impact can be significant. Join Dr. Gerry Clancy and University of Iowa liver specialists Dr. Marta Tejedor Bravo and Dr. Alan Gunderson as they explore risk factors, screening, disease progression, and emerging therapies that are reshaping care for patients with metabolic liver disease. Liver Wellness | The University of Iowa Iowa Liver Wellness Symposium: Cirrhosis Care in Motion 2026 5k Race - Run for Your Liver, Run for Your life (and last year's video Run for Your Liver, Run for Your Life) Episode Transcript CE Credit Available Host: Gerard Clancy, MD Senior Associate Dean for External Affairs Professor of Psychiatry and Emergency Medicine University of Iowa Carver College of Medicine Guests: Alan E. Gunderson, MD Clinical Associate Professor of Internal Medicine-Gastroenterology and Hepatology University of Iowa Carver College of Medicine Marta Tejedor Bravo, MD, MSc, PhD Clinical Associate Professor of Internal Medicine-Gastroenterology and Hepatology University of Iowa Carver College of Medicine Financial Disclosures:   Dr. Clancy, Dr. Tejedor Bravo, and the members of the Rounding@IOWA planning committee have disclosed no relevant financial relationships. Dr. Gunderson has disclosed the following relationships: CymaBay Therapeutics, Inc.; GigaGen, Inc.; LISCure Biosciences, Inc. - Sponsored Research Relevant financial relationships have been mitigated. Nurse: The University of Iowa Roy J. and Lucille A. Carver College of Medicine designates this activity for a maximum of 1.00 ANCC contact hour. Pharmacist and Pharmacy Tech: The University of Iowa Roy J. and Lucille A. Carver College of Medicine designates this knowledge-based activity for a maximum of 1.00 ACPE contact hours. Credit will be uploaded to the NABP CPE Monitor within 60 days after the activity completion. Pharmacists must provide their NABP ID and DOB (MMDD) to receive credit. JA0000310-0000-26-058-H01 Physician: The University of Iowa Roy J. and Lucille A. Carver College of Medicine designates this enduring material for a maximum of 1.00 AMA PRA Category 1 CreditTM. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Other Health Care Providers: A certificate of completion will be available after successful completion of the course. (It is the responsibility of licensees to determine if this continuing education activity meets the requirements of their professional licensure board.) References:  Rinella ME, Neuschwander-Tetri BA, Siddiqui MS, Abdelmalek MF, Caldwell S, Barb D, Kleiner DE, Loomba R. AASLD Practice Guidance on the clinical assessment and management of nonalcoholic fatty liver disease. Hepatology. 2023 May 1;77(5):1797-1835. doi: 10.1097/HEP.0000000000000323. Epub 2023 Mar 17. PMID: 36727674; PMCID: PMC10735173. European Association for the Study of the Liver (EASL); European Association for the Study of Diabetes (EASD); European Association for the Study of Obesity (EASO). EASL-EASD-EASO Clinical Practice Guidelines on the management of metabolic dysfunction-associated steatotic liver disease (MASLD). J Hepatol. 2024 Sep;81(3):492-542. doi: 10.1016/j.jhep.2024.04.031. Epub 2024 Jun 7. PMID: 38851997. Younossi ZM, Zelber-Sagi S, Lazarus JV, Wong VW, Yilmaz Y, Duseja A, Eguchi Y, Castera L, Pessoa MG, Oliveira CP, El-Kassas M, Tsochatzis E, Fan JG, Spearman CW, Tacke F, Castellanos Fernandez MI, Alkhouri N, Schattenberg JM, Romero-Gómez M, Noureddin M, Allen AM, Ong JP, Roberts SK, Shubrook JH, Burra P, Kohli R, Kautz A, Holleboom AG, Lam B, Isaacs S, Macedo P, Gastaldelli A, Henry L, Ivancovsky-Wajcman D, Nader F, de Avila L, Price JK, Mark HE, Villota-Rivas M, Barberá A, Kalligeros M, Gerber LH, Alqahtani SA. Global Consensus Recommendations for Metabolic Dysfunction-Associated Steatotic Liver Disease and Steatohepatitis. Gastroenterology. 2025 Oct;169(5):1017-1032.e2. doi: 10.1053/j.gastro.2025.02.044. Epub 2025 Apr 11. PMID: 40222485. Mladenić K, Lenartić M, Marinović S, Polić B, Wensveen FM. The "Domino effect" in MASLD: The inflammatory cascade of steatohepatitis. Eur J Immunol. 2024 Apr;54(4):e2149641. doi: 10.1002/eji.202149641. Epub 2024 Feb 5. PMID: 38314819. Harrison SA, Bedossa P, Guy CD, Schattenberg JM, Loomba R, Taub R, Labriola D, Moussa SE, Neff GW, Rinella ME, Anstee QM, Abdelmalek MF, Younossi Z, Baum SJ, Francque S, Charlton MR, Newsome PN, Lanthier N, Schiefke I, Mangia A, Pericàs JM, Patil R, Sanyal AJ, Noureddin M, Bansal MB, Alkhouri N, Castera L, Rudraraju M, Ratziu V; MAESTRO-NASH Investigators. A Phase 3, Randomized, Controlled Trial of Resmetirom in NASH with Liver Fibrosis. N Engl J Med. 2024 Feb 8;390(6):497-509. doi: 10.1056/NEJMoa2309000. PMID: 38324483. Sanyal AJ, Newsome PN, Kliers I, Østergaard LH, Long MT, Kjær MS, Cali AMG, Bugianesi E, Rinella ME, Roden M, Ratziu V; ESSENCE Study Group. Phase 3 Trial of Semaglutide in Metabolic Dysfunction-Associated Steatohepatitis. N Engl J Med. 2025 Jun 5;392(21):2089-2099. doi: 10.1056/NEJMoa2413258. Epub 2025 Apr 30. PMID: 40305708.  

In this Supplement Ingredients Series episode, Nurse Doza breaks down phosphatidylcholine—the phospholipid that makes up much of every cell membrane you have. He explains why your liver and brain hold the biggest stores of it, how the liver uses phosphatidylcholine to package and move fat, and why choline is the precursor your brain needs for acetylcholine, the neurotransmitter behind focus and memory. He also shares the simple two-capsule morning routine he's used for years. FEATURED PARTNER BodyBio PC is a phospholipid complex—not a choline salt—which means it delivers phosphatidylcholine in the form your cell membranes are actually built from. That's exactly the distinction Nurse Doza draws in this episode: after cycling through different sources and forms over the years, this is the one that stuck. It's stimulant-free, and his routine is two capsules in the morning on an empty stomach.

What is the difference between MASH and MASLD? In this special episode, Dr. Neil Skolnik breaks down these conditions, which affect insulin resistance of the liver, an area of increasing concern for people with diabetes. This special episode is sponsored with support from Lilly. Presented by: Neil Skolnik, MD, Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington Jefferson Health Jay Shubrook, DO, Professor and Diabetologist in the Department of Clinical Sciences and Community Health At Touro University California College of Osteopathic Medicine Susan Kuchera, MD, Program Director of the Jefferson Health Abington Family MedicineResidency Program and Associate Clinical Professor of Family and Community Medicine at the Sidney Kimmel Medical College of Thomas Jefferson University. References: Clinical Care Pathway for the Risk Stratification and Management of Patients With Metabolic Dysfunction–Associated Steatotic Liver Disease. Gastroenterology, 2026; 171, 164-183 Metabolic Dysfunction–Associated Steatotic Liver Disease (MASLD) in People With Diabetes: The Need for Screening and Early Intervention. A Consensus Report of the American Diabetes Association. Diabetes Care 2025;48(7):1057–1082 A Clinical Update on MASLD. JAMA Intern Med. 2025;185;(1):105-107. doi:10.1001/jamainternmed.2024.6431

Send us Fan MailAn 11-year-old looks a microphone in the face and calmly explains ulcerative colitis, colonoscopies, and anxiety like it's a skill she's been training for. Penny joins us live to share what diagnosis felt like in fourth grade, what she's learned about still living a full life, and why the prep can be harder than the procedure. Her honesty about nausea, fear of vomiting, and the way anxious thoughts snowball will sound painfully familiar to a lot of people with inflammatory bowel disease.We're also joined by Penny's mom, Sonia, a registered dietitian with digestive health training and an eating disorder specialty. We talk about food labels, restaurant unknowns, and finding a healthy balance that protects both the gut and the mind. Sonia shares what it's like to be both a clinician and a parent, how mental health support helps, and what it took to advocate for the right testing and the right IBD specialist.Then, still live from the Focus GI conference, we sit down with Grishelda and Rony Valme. Roni is a GI nurse, a creative on the conference media team, and an IBD patient himself. He tells his diagnosis story, breaks down how urgency reshapes travel, and gives the most practical “where do I go” bathroom advice you'll hear all week. We also dig into a message every new GI provider needs: believe patients, even when scopes and labs don't match the symptoms.If you want real-world ulcerative colitis and Crohn's disease coping strategies, patient-to-provider empathy, and practical IBD travel tips, hit play. Subscribe, leave a review, and share this with someone who needs to feel less alone.Links: FOCUS GIRony and Grishelda Valme's business!- Valme Photography and DesignSonia's practice- Colibri Nutrition TherapyLet's get social!!Follow us on Instagram!Follow us on Facebook!Follow us on Twitter!

You may have fatty liver disease and not even know it. In fact, it often develops silently, without obvious symptoms—but if left unchecked, it can lead to serious liver damage over time. So, what causes fatty liver disease? And most importantly, what can you do to protect your liver? On this episode of the Healthier You podcast, Dr. Ashlee Williams talks with Dr. Alex Jow, a board-certified gastroenterologist at Kaiser Permanente, about fatty liver disease—what causes it, how to know if you're at risk, and what you can do to improve your liver health.  Learn more about Alexander Jow, MD 

Advocacy doesn't begin in the legislature—it begins wherever nurses use their voices to improve care.  In this episode of Palliative Perspective, HPNA Advocacy Committee member Janelle Williamson MSN, NP-C, APRN, ACHPN, FPCN, and Kansas State Representative Melissa Oropeza DNP, APRN, NP-C, CGRN, join the conversation to explore how nurses can influence healthcare at every level. From sharing patient stories and engaging in professional organizations to testifying on legislation and serving in elected office, they discuss the many ways nurses can shape policy and advance the profession.  Together, they reflect on their own advocacy journeys, the leadership skills that grow from speaking up, and why nurses are uniquely qualified to inform healthcare decisions. The conversation also addresses a common challenge: many nurses don't see themselves as policy experts, despite being the clinicians closest to patients and families.  Whether you're attending your first advocacy event, participating in an HPNA Hill Day, or simply wondering where to begin, this episode offers practical insights and inspiration to help you discover where your voice can make a difference. Advocacy isn't reserved for a select few—it's a natural extension of nursing practice, and every nurse has a role to play. HPNA Advocacy  __________________________________________________________________________________________________________________________ Melissa Oropeza, DNP, APRN, NP-C, CGRN, is a board-certified Nurse Practitioner specializing in Gastroenterology at The University of Kansas Health System and a Kansas State Representative. With more than 27 years of healthcare experience, she has been a leader in advancing the role of Advanced Practice Providers and improving patient care through clinical practice, leadership, and advocacy.    Throughout her career, Dr. Oropeza has championed the nursing and advanced practice professions. She founded and served as the inaugural Chair of The University of Kansas Health System's Advanced Practice Providers (APP) Council, where she established professional recognition programs, created an APP endowment fund, and launched the institution's first APP Symposium. Her leadership has created lasting opportunities for professional development, recognition, and advocacy for advanced practice providers.    A nationally recognized healthcare advocate, Dr. Oropeza served on the Kansas State Board of Nursing and became the first actively practicing Nurse Practitioner elected to the Kansas House of Representatives in 2022. She currently serves as Chair of the Wyandotte-Leavenworth County Legislative Delegation and as Ranking Minority Member of the Kansas House Social Services Budget Committee, where she works to improve healthcare access, strengthen behavioral health services, and advance policies that support Kansas families and healthcare professionals.  In addition to her legislative service, Dr. Oropeza continues to provide direct patient care and mentor future healthcare leaders. She is a strong advocate for healthcare access, mental health, and patient-centered public policy. Her professional honors include the 2017 Kansas Nurse Practitioner Advocate Award and numerous leadership and service recognitions throughout her career. In 2026, she received the Legislative Leadership and Collaboration Award for Mental Health Advocacy, recognizing her commitment to building bipartisan solutions and improving mental health outcomes for Kansans.   Janelle Williamson, MSN, APRN, NP-C, ACHPN, FPCN, is a nurse practitioner with Palliative Medicine and Supportive Care at Stormont Vail Health in Topeka, Kansas. A nationally recognized leader in hospice and palliative care, she has held specialty certification in the field for nearly 15 years and was named a Fellow in Palliative Care Nursing in 2023—an honor recognizing significant contributions to the profession. She has been a strong advocate for improving access to palliative care across Kansas, helping lead efforts that established the state's Palliative Care and Quality of Life Advisory Council and contributing to Kansas' first five-year palliative care plan. Janelle also serves in leadership roles with the Kansas Advanced Practice Nurses Association and the Kansas Advanced Practice Nurses Association's Political Action Committee. She is passionate about advancing hospice and palliative care while advocating for APRNs to practice to the full extent of their education and training.

In our fourth Summer School episode this season, hosts Dr. Amber Hildreth and Dr. Jordan Whatley have taken highlights from past episodes on liver disease and put them into a special episode full of clinical pearls.Former expert guests Dr. Bill Balistreri, Dr. Jorge Bezerra, Dr. Saul Karpen, Dr. Dennis Black, Dr. Amy Taylor and Dr. Rohit Kohli cover neonatal cholestasis, biliary atresia, PSC, AIH, and MASLD.Our Bowel Sounds Summer School series will include four episodes each summer on big topics in our field, artisanally crafted for the ears of learners of all stages from the young student to the seasoned attending.Learning Objectives:Understand the evaluation of neonatal cholestasisReview the natural history of PSCReview the diagnosis and management of AIHUnderstand the diagnostic evaluation and management of MASLD.Featured episodes:1. Bill Balistreri- Neonatal Cholestasis2. Jorge Bezerra- Advances in Biliary Atresia3. Saul Karpen- Updates in Biliary Atresia4. Dennis Black- Primary Sclerosing Cholangitis5. Amy Taylor- Autoimmune Hepatitis Management6. Rohit Kohli- Fatty Liver DiseaseAdditional Links:1. Guideline for the Evaluation of Cholestatic Infants2. AASLD PSC Guidelines3. AASLD AIH GuidelinesSend us Fan MailSupport the showThis episode may be eligible for CME credit!  Once you have listened to the episode, click this link to claim your credit.  Credit is available to NASPGHAN members (if you are not a member, you should probably sign up).  And thank you to the NASPGHAN Professional Education Committee for their review!As always, the discussion, views, and recommendations in this podcast are the sole responsibility of the hosts and guests and are subject to change over time with advances in the field.Check out our merch website!Follow us on Bluesky, Twitter, Facebook and Instagram for all the latest news and upcoming episodes.Click here to support the show.

One camp says your reflux is too much stomach acid. The other says it's too little. Dr. Ken Brown says both camps are arguing over the wrong control knob.In this solo episode, the board-certified gastroenterologist makes the case that reflux was never an acid problem - it's a containment problem. Acid belongs in the stomach, and the real question nobody asks is why it left in the first place.Dr. Brown walks through the mechanics: the stomach as a one-way muscular pump, the lower esophageal sphincter as a nightclub bouncer who's started letting people back out the front door, the "acid puddle" that pools when the stomach won't empty, and the inflammation cycle that weakens the valve and keeps the whole thing self-sustaining. He looks at what 37 years of proton pump inhibitors have actually delivered - eight-plus drugs, an 83% rise in documented GERD, and a side effect list that includes bone, B12, magnesium, and kidney concerns - and points out that PPIs don't improve gastric emptying, don't reduce abdominal pressure, and don't strengthen the sphincter.He also tells his own story: 30 years of reflux, a four-centimeter hiatal hernia, grade C esophagitis, every natural remedy on the shelf, and the eight-year project to build something that addressed the mechanism instead of the symptom - the four-polyphenol Re:Flux formula and the clinical trial behind it, recently published in the Open Journal of Gastroenterology.In this episode:- Why the "too much vs. too little acid" debate misses the mechanism- How your stomach actually works as a one-way cycling pump- Transient lower esophageal sphincter relaxations, explained without the jargon- The acid puddle, and why gastric sleeve and GLP-1 patients get it- What stomach acid is genuinely for (B12, minerals, pathogen defense)- The three questions to ask instead of "how much acid?"- What PPIs do well, and what they were never designed to do- The HAND polyphenols and the trial resultsChapters: 0:00 The wrong debate · 2:45 Two camps · 4:15 37 years of PPIs · 7:48 The one-way pump · 12:39 The acid puddle · 14:18 Why the valve opens · 17:15 Why you need acid · 18:59 Three better questions · 21:08 What PPIs can't do · 23:07 Dr. Brown's own 30 years · 26:20 Building the formula · 28:40 Trial results · 33:45 Acid is not the villainEducational content only - not medical advice. Never stop a prescription medication without talking to your physician first.Learn more: regardingyourgut.com · kbmdhealth.com · @kbmdhealthBrought to you by Atrantil Pro.

Have you been struggling with gut issues for years, or suddenly have bloating, weird pain or digestive problems now that menopause is here? Are you one of those who cut out gluten hoping for relief, only to feel just as lousy (or worse)? We cover: Why your gut goes a little haywire in menopause, and why it has nothing to do with "just getting older" The gluten truth that made me rethink everything I put in my mouth (most of us get this completely backwards) How simply believing a food will hurt you can physically make it hurt you, and what that means for your power to change it A free international study you can join from your couch if you're dealing with IBS The one simple shift that beats probiotics and cutting out foods for a calmer gut   Associate Professor Jessica Biesiekierski is Head of Human Nutrition at the University of Melbourne and one of Australia's leading researchers in gut health, diet, and gut–brain interaction. Jess leads large international randomised controlled trials investigating how dietary and psychological interventions can improve gut conditions like Irritable Bowel Syndrome (IBS). Her work has been published in top journals including The Lancet, Gastroenterology, and The American Journal of Gastroenterology. She is internationally recognised for her research on non-coeliac gluten sensitivity, the low FODMAP diet, and how gut–brain mechanisms shape food-related symptoms. She currently leads the world-first head-to-head study comparing the low FODMAP diet with exposure-based cognitive behavioural therapy in people with IBS, recruiting across Australia and the USA.   Clinical trial — the Exclude or Expose Study in IBS — which is actively recruiting adults with IBS in both Australia and the USA. The trial compares two leading, evidence-based IBS treatments head-to-head for the first time: the low FODMAP diet (an exclusion-based dietary approach) versus exposure-based cognitive behavioural therapy (which works by helping the brain respond differently to gut symptoms and feared foods). Both are delivered entirely online over 12 weeks, free of charge, with one-on-one support from a dietitian or psychologist throughout. Many women experiencing gut symptoms around menopause may qualify. Trial website: www.gutresearchstudy.com NERVA app (gut-directed hypnotherapy): https://www.nervahealth.com/eu   Contact Jess Biesiekierskie: Email: gut-research@unimelb.edu.au University of Melbourne staff profile: https://findanexpert.unimelb.edu.au/profile/827643-jessica-biesiekierski Linkedin: https://www.linkedin.com/in/jessica-biesiekierski-78b61730/ Instagram: @human_nutrition_research Facebook: Human Nutrition Research Twitter: @jrbiesiekierski Give thanks to our sponsors: Try Vitali skincare. 20% off with code ZORA here - https://vitaliskincare.com Get Primeadine spermidine by Oxford Healthspan. 15% discount with code ZORA ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ - https://www.oxfordhealthspan.com/ZORA Get Mitopure Urolithin A by Timeline. 20% discount with code ZORA at https://timeline.com/zora Try MitoQ for optimal mitochondrial health. Code ZORA for 20% off https://mitoq.com/zora   Join the Hack My Age community on: YouTube: https://youtube.com/@hackmyage Facebook Page: ⁠⁠⁠⁠⁠@⁠Hack My Age⁠     Facebook Group: ⁠⁠⁠⁠⁠⁠@⁠Biohacking Menopause⁠⁠⁠⁠⁠⁠ ⁠   Biohacking Menopause Private Women's Only Support Group: https://membership.hackmyage.com/sales-page  Instagram: ⁠⁠⁠⁠⁠@⁠HackMyAge⁠    Website: ⁠⁠⁠⁠⁠⁠HackMyAge.com⁠    For partnership inquiries: https://www.category3.ca/  Some episodes of Hack My Age are supported by partners whose products or services may be discussed during the show. The host may receive compensation or earn a minor commission if you purchase through affiliate links at no extra cost to you. All opinions shared are those of the host and guests, based on personal experience and research, and do not necessarily represent the views of any sponsor. Sponsorships do not imply medical endorsement or approval by any healthcare provider featured on this podcast.

Send us Fan MailA Saturday training that changes how you practice on Monday is rare, and that's exactly what FOCUS GI is designed to do. We recorded live from the event with Dr. Anish Patel, the nonprofit founder behind FOCUS GI, plus Dr. Richa Shukla (course director) and Dr. Kevin Pak (hepatologist) to talk about what happens when medical education is built for real clinic decisions, not ego or noise.We get into why the program started in Central Texas, how it grew from a small local idea into a hybrid event serving GI fellows and advanced practice providers across states and even countries, and what “clinically oriented” really means in practice. You'll hear how the team chooses speakers, updates topics, and protects hands-on learning, especially for first-year GI fellows facing a steep learning curve and nonstop consult questions. We also unpack how the APP and fellow track serves different needs while strengthening the same GI care team.Then we go deeper into the human side of IBD care: hope and trust. Dr. Patel explains why “hope” is the point of provider education, while “trust” is the skill that makes treatment partnerships work, especially when patients have normalized symptoms for years. We also tackle misinformation head-on, including the growing role of social media influencers in shaping IBD myths. Along the way, Dr. Pak shares why accurate FibroScan interpretation matters and how misreads can send patients down the wrong clinical pathway, and Dr. Shukla reflects on patient education around medication risks and how to talk about scary side-effect lists with real numbers and context.Subscribe for more live conversations from FOCUS GI, and if this helped you, please share it with a colleague or friend and leave a review so more patients and providers can find it.Links: FOCUS GI websiteDr. Richa ShuklaFOCUS GI's Facebook pageLet's get social!!Follow us on Instagram!Follow us on Facebook!Follow us on Twitter!

In this session, attendees will be equipped to navigate the discernment process of identifying the best-fit sending agency for them.

Dr. Lisa Mathew interviews Dr. Vivek Kaul, professor of medicine in the Division of Gastroenterology and Hepatology at the University of Rochester Medical Center, about the arrival of a new technology and its endorsement in society guidelines, and how clinical practice models help physicians decide whether to adopt something new before the guidelines arrive. Kaul served as project coordinator for the clinical practice model for TissueCypher, a test that predicts a patient's risk of progression from Barrett's esophagus to esophageal cancer. Gastroenterologists from academic centers, health systems, and private practice considered current risk stratification in Barrett's and developed a playbook for the practical questions that come with adopting a new test like TissueCypher, such as which patients are appropriate candidates, how to raise the option, and what a result means for the next steps in care. Join Dr. Mathew and Dr. Kaul as they examine how societies produce guidelines and why the process takes time, which practice settings are represented in a clinical practice model, and how a physician in private practice can decide whether the model fits their patients. Produced by Andrew Sousa and Hayden Margolis for Steadfast Collaborative, LLC Mixed and mastered by Hayden Margolis Gastro Broadcast, episode 95, presented by TissueCypher from Castle Biosciences

Dubai resident Dunia Obaidy says she tried numerous diets, two bariatric procedures and GLP-1 medication, but continued to struggle with hunger and weight regain. She has now lost 19kg following a new, minimally invasive endoscopic treatment called gastric mucosal ablation. Dunia joins us alongside the doctor who performed the procedure, Dr Mohamed Abdelhafez, Consultant in Gastroenterology at Medcare Royal Speciality Hospital in Dubai. Former Emirates cabin crew member Sharlene Lowe visited more than 200 cities and became the person passengers and colleagues turned to for honest, practical travel advice. She has now turned that experience into Tripsy, an AI-powered travel companion designed with women’s safety in mind. What are the laws around plagiarism on social media? Ankita Dhawan, Founder and Principal of Consilium Advisors and Technology Policy Advisors, explains how copying someone's work can get you in legal trouble. Family holidays are supposed to be the reward for months of work, school runs and relentless routine. But the person researching the hotel, packing the cases, remembering the medication, booking the activities and anticipating everybody’s needs may arrive already exhausted. Recent mental-health guidance warns that the gap between how we imagine a holiday should feel and how it actually unfolds can create stress, disappointment and resentment. Dr Haneen Jarrar is Director of Child and Adolescent Services and a Child Psychologist at The Free Spirit Collective.See omnystudio.com/listener for privacy information.

When you decide to grab a bite to eat, do you think about how to feed your gut microbes? Most of us don't. Even if we did, their only means of stating their preferences is somewhat after the fact. Do you end up feeling less than well? Perhaps the denizens of your gut aren't happy. In this episode, we consider how to support your microbiota and whether that can reduce the inflammation that seems to accompany modern life. At The People's Pharmacy, we strive to bring you up‑to‑date, rigorously researched insights and conversations about health, medicine, wellness and health policies and health systems. While these conversations intend to offer insight and perspective, the content is provided solely for informational and educational purposes. Please consult your healthcare provider before making any changes to your medical care or treatment. How You Can Listen You could listen through your local public radio station or get the live stream at 7 am EST on Saturday, August 15, 2026, through your computer or smart phone (wunc.org). Here is a link so you can find which stations carry our broadcast. If you can't listen to the broadcast, you may wish to hear the podcast later. You can subscribe through your favorite podcast provider, download the mp3 using the link at the bottom of the page, or listen to the stream on this post starting on August 17, 2026. Feed Your Gut Right to Fight Inflammation Dr. Will Bulsiewicz is a gastroenterologist who urges all of us to focus on a healthful fiber-rich plant-strong diet to maintain our microbiome in good shape. He has described his own evolution from a busy medical student relying heavily on processed food products to a whole-food plant-based enthusiast. Eating a wide variety of plants is one of the easiest ways to make sure we are getting the nutrients our gut microbes need. Why are the trillions of microbes in our large intestine so important? Dr. Bulsiewicz (aka Dr. B.) shares the story of a patient who was overwhelmed by a serious C. diff infection. A course of clindamycin for a skin infection had decimated her normal microbiome and left an open field for C. diff to flourish. Instead of treating her with surgery and even more potent antibiotics, Dr. B. and his colleagues utilized a fecal transplant. She got poop from a healthy person into her colon and left the hospital a few days later in good health herself. What Is the Link Between the Microbiome and the Immune System? Inflammation is one of the primary signs that the immune system has gone into action to fight off a perceived foe. There is a close relationship between the gut microbes, the gut barrier and the cells of the immune system. Between 70 and 80 percent of immune system cells are present in the gut (Nutrients, March 9, 2021).  There is just one layer of cells in the gut barrier, firmly attached to each other through tight junctions. If those tight junctions break down, pathogens and toxins can get from the gut into the bloodstream and activate the immune system into creating inflammation Medicines That Harm the Intestinal Barrier Diets that are high in salt have a negative impact on the integrity of the intestinal barrier (Nutrients, Nov. 25, 2025). In fact, a diet high in salt can reduce the number of Lactobacilli in the gut by 90%. This also affects the permeability of the gut barrier, which can contribute to auto-immune conditions. When we asked about inflammatory bowel disorders such as Crohn disease or ulcerative colitis, Dr. B. told us he thinks it's a mistake to classify them as auto-immune conditions. Instead, he suggests we should consider these conditions as due to the immune system rejecting the microbiome. Some of them might be initiated and perpetuated by failures in the gut barrier that allow certain organisms or their toxins into systemic circulation. A number of medications can also harm it, most notably the nonsteroidal anti-inflammatory drugs (NSAIDs). Agents like ibuprofen, naproxen, celecoxib and meloxicam may disrupt the tight junctions that keep the intestinal barrier intact (Gastroenterology, Feb. 2018).  In some cases, they may also upset the balance of microbes. Four Keys to an Anti-Inflammatory Diet There are several different dietary patterns that allow you to feed your gut and fight inflammation. Good evidence supports a DASH diet, a Mediterranean diet, pescatarian, flexitarian, vegetarian and some vegan diets. We asked Dr. B. to summarize the four features healthful eating patterns share. They include adequate fiber, plenty of polyphenols, healthy fat and fermented foods (think of sauerkraut or kimchi). Fiber and Flatulence One drawback of a high-fiber diet is that when microbes in the colon ferment the fiber we can't digest, they produce gases. It has to go somewhere, or it will cause sensations of cramping and bloating. Consequently, fiber is often associated with flatulence. Dr. B. suggests that there may be more gas, and it may be loud, but it shouldn't be stinky. Smelly farts are born of sulfur, which is more common in a diet containing garlic, onions, crucifers like broccoli or cabbage, fish, eggs or meat. Plant-Powered Plus We wondered what might be included in the “plus” category when you feed your gut and fight inflammation. Dr. B. offers a few things that you might not expect in a book about diet, but they are related to reducing inflammation. One is to go outside early in the day, every day, to get your circadian rhythm in sync. Another is to maintain your emotional connections with family and friends. Still another, just as important, is to nurture your spiritual core. This Week’s Guest Dr. Will Bulsiewicz describes how a plant-powered diet can fight inflammation Will Bulsiewicz, MD, is a New York Times bestselling author, award-winning gastroenterologist and internationally recognized health expert. Dr. Bulsiewicz directs the Gut & Microbiome Center for Excellence, a physician-led executive medicine and telemedicine practice based in Mount Pleasant, SC. Dr. Bulsiewicz is the author of several books, including his latest book, Plant Powered Plus: Activate the Power of Your Gut to Tame Inflammation and Reclaim Your Health. His website is https://theguthealthmd.com/books/ The People's Pharmacy is reader supported. When you buy through links in this post, we may earn a small affiliate commission (at no cost to you). Listen to the Podcast The podcast of this program will be available Monday, August 17, 2026, after broadcast on Aug. 15. In this week's podcast, you get to peek into Dr. B's shopping cart. Are you buying the same vegetables he does? We also get insights on his favorite recipes for grains like farro. And we discuss the effect of coffee on the gut microbes. If you want to feed your gut to encourage certain microbes, remember that consistency is crucial. You can't eat a specific food once and expect it to make a difference. But consuming it several times a week will ultimately add up. We also discuss antidotes for flatulence, if you are interested in that. You can stream the show from this site and download the podcast for free. Download the mp3, or listen to the podcast on Apple Podcasts or Spotify.

Send us Fan MailA colonoscopy that comes back normal can feel like relief, until your body keeps proving something is wrong. We sit down with Dr. Matthew J. Simpson, a family medicine physician in North Carolina, to unpack how he lived with Crohn's disease symptoms for years without a clear diagnosis, and why a perianal fistula finally forced the medical system to see the full picture. If you've ever been told your labs look fine while you're dealing with bleeding, urgency, fatigue, or weight loss, you'll hear your reality reflected back with empathy and precision. We talk about what it's like to chase answers while living outside a major medical hub: limited local gastroenterology options, slow referral pipelines, insurance approvals, and fragmented care between GI, colorectal surgery, and imaging. Matthew walks us through the flex sig, MRI findings, and the moment he realized he needed an IBD specialty clinic and an academic medical center approach. His story is a clear reminder that “not unreasonable” care can still be the wrong pace when your health is sliding. Then we get practical. Matthew explains perianal fistulas in plain language, what a fistulotomy does (and does not do), and why healing often requires treating the underlying Crohn's inflammation. We also dig into shared decision making for Crohn's medications, including how he weighed biologic options, risk communication, and the added complexity of carrying a BRCA2 gene mutation. Along the way, we challenge overreliance on single tests like fecal calprotectin and zoom out to the bigger point: algorithms are helpful, but they are not your lived experience. If this conversation helps you feel less alone, please subscribe, share it with someone navigating IBD, and leave a review so more people can find the show.Links: What is anorectal manometry?- Cleveland ClinicFistulotomy- Cleveland ClinicLet's get social!!Follow us on Instagram!Follow us on Facebook!Follow us on Twitter!

Coeliac disease is often viewed as a straightforward gastrointestinal condition, but its presentation, diagnosis and long-term management can be far more complex than many clinicians appreciate.In this episode of the RCP Medicine Podcast Dr. Dushen Murugiah, Consultant Gastroenterologist and Trust Lead for Nutrition at Royal Surrey County Hospital NHS Foundation Trust, joins Dr Abhishek Ray to explore the modern approach to coeliac disease.Together they discuss classical and non-classical presentations, the challenges of diagnosing an often under-recognised condition, the role of serology and small bowel biopsy, and the importance of considering celiac disease in patients presenting with unexplained anaemia, nutritional deficiencies and other extraintestinal manifestations. The conversation also explores refractory celiac disease, practical challenges associated with lifelong gluten avoidance, and promising future therapies currently under investigation.This episode offers practical, evidence-informed insights for physicians, trainees and healthcare professionals involved in the assessment and management of patients with suspected or confirmed coeliac disease.  Explore our CPD portfolio by your career stageEducation and professional developmentLeadership CPDTeach the teacherEducational supervisorSix-step programme RCP Social MediaInstagramLinkedInFacebookBlueskyMusic Ep 50 onward - Bensound.com  Ep 1 - 49 'Impressive Deals' - Nicolai Heidlas Any adverts within this podcast may use computer generated voices

Naturopathic gastroenterologist Mark Davis, ND (FABNG), discusses his work in fecal microbiota transplantation (FMT), research, and integrative approaches to GI disease. Davis explains FMT history, screening criteria, delivery methods, how it differs from probiotics, and why it is highly effective for recurrent C. difficile (about a 90% durable cure), while noting FDA-approved products (Rebyota, Vowst) and off-label applications. He describes IRB-approved studies on naturopathic care for IBS and ulcerative colitis and a blinded project comparing consistency across 15–20 stool microbiome labs. The conversation covers evidence for diet in IBS/IBD (including SCD and a semi-vegetarian diet), low-FODMAP as a temporary tool, breath testing and relapse in SIBO, helminthic therapy options and legality, targeted probiotics (Saccharomyces boulardii, Akkermansia, soil-based species), enema therapies, indigo naturalis benefits and risks, saffron evidence for mood, telemedicine practice, and a crowdfunding platform for clinical trials.

Dr. Hoffman continues is conversation with naturopathic gastroenterologist Mark Davis, ND (FABNG).

As cyclosporiasis infections increase across the U.S., an expert from Children's Health discusses clinical guidance for community providers and how to recognize infections in children.  Learn more about Dr. Most.

Four inflammatory bowel disease (IBD) experts explore case-based strategies for optimizing advanced IBD therapy and long-term disease management early in real-world practice. They discuss practical approaches for implementing treat-to-target via strategic treatment sequencing, therapeutic drug monitoring, and maintenance approaches while supporting individualized, evidence-based care for patients with IBD. Presenters Jessica R. Allegretti, MD, MPH, FACG, AGAF Medical Director, Infusion Services Director, Crohn's and Colitis Center Director of Clinical Research Director, Fecal Microbiota Transplant Program Division of Gastroenterology, Hepatology and Endoscopy Brigham and Women's Hospital Associate Professor of Medicine, Harvard Medical School Boston, Massachusetts Jordan E. Axelrad, MD, MPH, AGAF, FACG, FCCF Co-Director, Inflammatory Bowel Disease Center at NYU Langone Health Associate Professor of Medicine Division of Gastroenterology and Hepatology NYU Grossman School of Medicine New York, New York Russell D. Cohen, MD, FACG, AGAF Professor of Medicine, Pritzker School of Medicine Co-Director, Digestive Diseases Center Clinical Director, Inflammatory Bowel Disease Center Co-Director, Advanced IBD Fellowship Program The University of Chicago Medicine Chicago, Illinois Amy Stewart, MSN, FNP-C Lead Advanced Practice Provider Capital Digestive Care Washington, DC Link to full program: https://bit.ly/4wvm7l4 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

In our second Summer School episode this season, hosts Dr. Jason Silverman and Dr. Temara Hajjat have taken highlights from past episodes on nutrition and put them into a special episode full of clinical pearls.Former expert guests Dr. Charlie Vanderpool, Dr. Mark Corkins, Dr. Praveen Goday, Dr. Maria Mascarenhas, Dr. Ruba Abdelhadi, Dr. Bruno Chumpitazi and Kirsten Jones, and Dr. Eytan Wine cover a range of topics from early life nutrition and development, to picky eating and specialized diets.Our Bowel Sounds Summer School series will include four episodes each summer on big topics in our field, artisanally crafted for the ears of learners of all stages from the young student to the seasoned attending.Learning Objectives:Understand the importance of functional components of human milk and other early life influences on growth and development.Review an approach to the evaluation and management of the picky eater.Review the indications and evidence for specialized diets in the context of gastrointestinal disorders.Featured Episodes:Charlie Vanderpool - Functional Components in Infant NutritionMark Corkins - Early Life Nutrition and Impact on Childhood DevelopmentPraveen Goday - The Picky EaterRuba Abdelhadi - Enteral Nutrition and Feeding Tubes 101Eytan Wine - Nutrition, IBD, and the Crohn's Disease Exclusion DietBruno Chumpitazi & Kirsten Jones - Using the Low-FODMAP Diet for Children with IBSMaria Mascarenhas - Culinary MedicineAdditional links:Lisa Richardson - Ins and Outs of Infant FormulasKatie Larson-Nath - Faltering WeightNutrition Pearls PodcastSend us Fan MailSupport the showThis episode may be eligible for CME credit!  Once you have listened to the episode, click this link to claim your credit.  Credit is available to NASPGHAN members (if you are not a member, you should probably sign up).  And thank you to the NASPGHAN Professional Education Committee for their review!As always, the discussion, views, and recommendations in this podcast are the sole responsibility of the hosts and guests and are subject to change over time with advances in the field.Check out our merch website!Follow us on Bluesky, Twitter, Facebook and Instagram for all the latest news and upcoming episodes.Click here to support the show.

In this episode, we spoke with Dr. Tatyana Kushner, Associate Professor of Medicine in the Department of Gastroenterology at Weill Cornell Medicine in New York. Dr. Kushner discusses hepatitis B treatment during pregnancy, including when antiviral therapy is recommended to help prevent mother-to-child transmission, and the importance of continuing hepatitis B care and treatment after pregnancy to support long-term liver health.Support the showOur website: www.hepb.orgSupport B Heppy!Social Media: Instagram - Twitter - Facebook

In this episode of Better Edge podcast, Rajesh N. Keswani, MD, explores major advances within the Northwestern Medicine Pancreas Program, including standardized pancreatitis care and findings from key trials. He also highlights progress in high‑risk pancreatic cancer surveillance and the expanding use of AI to enhance early detection and diagnostic accuracy.

Send us Fan MailThe fastest way to improve IBD outcomes is not always a new drug. Sometimes it's a better system and a team that can actually reach you before you end up in crisis. We're joined by Dr. Corey Siegel, a renowned gastroenterologist and IBD specialist at Dartmouth Hitchcock Medical Center, to unpack what “high-quality inflammatory bowel disease care” looks like when you measure it, stress-test it, and rebuild it around real patient needs.We talk through IBD Qorus, the Crohn's and Colitis Foundation quality improvement program that defines key standards for Crohn's disease and ulcerative colitis care and then tracks whether clinics meet them. That leads to a practical, patient-first goal: keeping people out of the emergency department by creating urgent clinic access, proactively supporting high-risk patients, and using better visit workflows that start with the patient's top concern. These aren't flashy changes, but they reduce prednisone use, unnecessary CT scans, opioid exposure, and the emotional toll of feeling unheard.Then we zoom out to rural healthcare and specialty access. Dr. Siegel explains RADIUS, a telemedicine “hub-and-spoke” model where community practices connect patients early to a full multidisciplinary IBD team, including behavioral health, nutrition, pharmacy support, and nursing coordination. We also get real about treat-to-target, why symptoms can mislead, and how insurance barriers like prior authorization and step therapy can delay the right biologic or advanced therapy for months.If you want smarter, more human IBD care and concrete ideas you can advocate for, hit play now. After you listen, subscribe, share with a friend, and leave a review so more patients can find these conversations.Links: Dr. Siegel's podcast- Digesting: The Latest in IBD- apple podcastsSpotify optionInformation on IBD Qorus- Crohn's & Colitis Foundation Information about the BRIDGe GroupLet's get social!!Follow us on Instagram!Follow us on Facebook!Follow us on Twitter!

Co-hosts Ryan Piansky, a patient advocate living with eosinophilic esophagitis (EoE) and eosinophilic asthma, and Holly Knotowicz, a speech-language pathologist living with EoE who serves on APFED's Health Science Advisory Council, interview Dr. Claire Beveridge about EoE and dysphagia. Disclaimer: The information provided in this podcast is designed to support, not replace, the relationship between listeners and their healthcare providers. Opinions, information, and recommendations shared in this podcast are not a substitute for medical advice. Decisions related to medical care should be made with your healthcare provider. Opinions and views of guests and co-hosts are their own.   Key Takeaways: [:49] Co-host Ryan Piansky introduces this episode, brought to you thanks to the support of Education Partners AstraZeneca, GSK, Sanofi, Regeneron, and Takeda. Ryan introduces co-host Holly Knotowicz.   [1:17] Holly introduces today's topic, research on eosinophilic esophagitis (EoE) and dysphagia.   [1:24] Holly introduces and welcomes today's guest, Dr. Claire Beveridge, a gastroenterologist at the Cleveland Clinic. Dr. Beveridge heads the EoE Adult Clinic and the Transition from Pediatric to Adult EoE Clinic.   [1:36] Holly, a speech pathologist, says she is very excited to dive into the research Dr. Beveridge did with EoE and dysphagia. Holly asks Dr. Beveridge to share some of her background.   [1:48] Dr. Beveridge was recruited to the Cleveland Clinic about five years ago to head the EoE Center. She loves the work they have done there.   [1:57] Dr. Beveridge says it's been nice to center everything on their EoE patients and have multidisciplinary care with speech-language pathologists, allergists, dietitians, pulmonologists, and more. It's been a great experience.   [2:15] Dr. Beveridge says the other thing they are really proud of is having a Transition Clinic. It can be tough for patients to transition from pediatric to adult care.   [2:23] Dr. Beveridge says this is something she was inspired to do when she was finishing her training at the University of Pennsylvania, where they had been doing some of that. It was really important to her when she joined Cleveland Clinic.   [2:34] Dr. Beveridge, with her Co-director, Dr. Sophia Patel, helps patients transition from pediatric to adult care.   [2:41] Holly speaks of the challenge of transitioning from pediatric care at a multidisciplinary clinic to adult care.   [3:08] Dr. Beveridge says you can't do any training at Northwestern without loving the esophagus. She did her residency there, got exposed to esophagology, and got to know Dr. Gonsalves and Dr. Hirano really well.   [3:33] Drs. Gonsalves and Hirano are really big names in EoE. Dr. Beveridge was fascinated by the disease. She loved the patients and wanted to help them and make them feel better. It's a burgeoning field.   [3:48] Dr. Beveridge says that it's only in the last few years that we have had FDA-approved medications for it, and that we have been jerry-rigging asthma medications to treat our patients.   [4:03] Dr. Beveridge says it's really exciting to see the treatment options we can offer.   [4:10] Ryan says it's exciting to see how EoE management has changed.   [4:16] Ryan says we see so many patients who are untreated or poorly treated for years, who have restructuring of their esophagus and present with dysphagia, or have strictures and rings leading to food impactions; the long-term effects of untreated EoE.   [4:34] Ryan says it's exciting that now we do have better treatment options for people, right off the bat.   [4:43] Dr. Beveridge conducted some research on EoE and dysphagia and presented a poster at the 2024 Digestive Diseases Week.   [4:51] The poster was titled, "Esophageal Luminal Diameter is Associated with Dysphagia and Eosinophilic Esophagitis: Implications for Endoscopic Dilation Therapy."   [5:11] Dr. Beveridge says dysphagia means issues with swallowing. It's a feeling of something getting stuck or something slowly moving down. There are also subtle symptoms that can happen.   [5:31] Dr. Beveridge says patients who have had EoE for a long time become accustomed to how they swallow. Things a patient may think are normal, like needing water and taking a sip after each bite, are learned accommodating behaviors.   [5:58] Dr. Beveridge says accommodating behaviors are that you're needing to imbibe extra water, you're modifying how you're eating, extra chewing, avoiding pills, avoiding other certain foods, and things like that that can be modifying factors.   [6:19] So, difficulty with swallowing, things getting stuck, slowly moving down, but also keeping in mind some of those modifying behaviors that we may end up using.   [7:23] Dr. Beveridge says her motivation was seeing patients in her clinic who were having persistent symptoms, and getting them into histological remission. The goal of treating your EoE is to get the eosinophils less than 15; close to zero is great.   [7:45] Dr. Beveridge says we have patients who, despite doing their endoscopies and taking biopsies, things look fine; they're still having issues with swallowing. Why is that the case?   [7:58] Dr. Beveridge says in a different research paper she had done, looking at some of the predictors for that, one of them was fibrostenosis. There are also other things that can contribute, like esophageal hypervigilance and a fear of swallowing.   [8:21] If a patient has had a food impaction, it's going to be scary to try to swallow again. Some of it is behavioral, but some of it is structural. At what luminal diameter (the size of the esophagus) is that causing a clinical problem for patients?   [8:45] A normal esophagus is 20 to 24 mm in diameter. Traditionally, around 14 to 16 mm in diameter has been when we say that patients get symptoms or they're feeling the issues with swallowing.   [9:03] Dr. Beveridge says a lot of those studies have never been done specifically for EoE patients.   [9:08] Dr. Beveridge wanted to know, if we exclude cancer, if we exclude acid reflux, and all of these other things, and just look at our EoE patients, what size of the esophagus are we looking at?   [9:20] Dr. Beveridge explained they specifically looked at patients whose histology was under control and then compared those who continued to experience symptoms with those who did not. The goal was to determine the histologic threshold at which patients begin to experience dysphagia.    [9:54] Dr. Beveridge says they saw this threshold at 16 mm (1.6 cm). That's still quite the difference from a normal esophagus of 20 to 24.   [10:08] Dr. Beveridge says our esophagus can definitely handle being smaller, but then, once you get to that 16 mm, for a lot of patients, it really does cause that feeling of things getting stuck or slowly moving down.   [10:20] Holly says what's cool about the retrospective data Dr. Beveridge looked at, and the parameters she placed in the research, is that when a patient goes in for an endoscopy, the doctor can measure and say maybe this is why dysphagia is going on.   [10:48] Holly finds that adult patients with food impactions are scared to eat the same food again. She loves having this data to share with patients and say, let's look at what your esophagus measures at. Let's do a smaller bite. Let's add a dip and liquid.   [11:12] Holly says data can push so much progress. Holly, having multiple chronic illnesses, loves when doctors can say, this is going to be safe. This is the mode that we're going to go with.   [11:30] Dr. Beveridge says in the retrospective study, they were looking at stuff that had already been done. We decided from here to assess patients more prospectively. All of this was based on chart review from when the note said symptoms or no symptoms.   [11:53] Dr. Beveridge says when she started this EoE clinic at the Cleveland Clinic, part of it was to standardize better how we were collecting data from patients to understand their symptoms.   [12:07] Dr. Beveridge has a standardized questionnaire for patients to understand if they are having heartburn and difficulty with swallowing, so she can know that at each point of their endoscopy.   [12:18] Dr. Beveridge says it will be nice, hopefully in the future, when she can give a little more detail and depth in terms of assessing this more prospectively and seeing if that same number holds up or if she needs to tweak it a little bit.   [12:34] Holly thinks it's fascinating. Numbers give us so much information, to know if my mm is this versus this, the next time, or during allergy season or not.   [12:53] Ryan says it's cool that you're able to look back at existing patient records and identify this information. Now we have that 16 mm number in mind to say maybe this is where we'll start to see increased risk of dysphagia in these patients.   [13:28] Dr. Beveridge says, how we had to do it retrospectively was based on the endoscopist estimating what the size is. Gastroenterologists recognize they're not always the best at estimating the size of the esophagus.   [13:50] Dr. Beveridge says, if your endoscope could not pass through, or it was snugly passing through, you know the diameter of the endoscope. If a dilation was done, at what size dilation do we start to see a disruption?   [14:19] Dr. Beveridge says, the goal of a dilation is to get a disruption because there's scar tissue we want to break open. A patient might think disruption means a perforation or something more scary, but that is the goal. We want to break open that scar tissue.   [14:42] Dr. Beveridge says, once we see that scar tissue break open a little bit, then we can estimate what the diameter is, based on the size dilator we used.   [15:10] Dr. Beveridge says for adults, we use a standard adult upper endoscope, and that's about 13 mm. The ones we use for kids are about 6 mm.   [15:35] Dr. Beveridge says the adult endoscope is around 13 mm, and it's around 14 to 16 mm when we start to see the symptoms.   [16:07] Dr. Beveridge says there are two main types of dilation that we do. One is the Savary dilator or wire-guided dilator, a long dilator that stretches the entire esophagus, from the mouth down to the stomach.   [17:20] Dr. Beveridge says another way of doing it is while you have the endoscope in, you thread a catheter. At the end of the endoscope, there's a balloon. You fill the balloon with saline up to different sizes. Typically, they go up by 3 mm, so 12 to 15 mm.   [18:01] Dr. Beveridge says the catheter balloon dilator is good for discrete strictures because the balloon isn't going to do the entire esophagus; it's just going to do one area of the esophagus, and you're watching it the whole time.   [18:19] For the wire dilator, you remove the scope. You're not able to see, so it's important to assess ahead of time how narrow things are, so you start at a safe dilation. You go in each time to see if there's starting to be disruption, and then you can do more.   [18:44] Holly asks if a gastroenterologist doing an upper endoscopy with sedation sees that it's tight, would the gastroenterologist automatically do a dilation? Or, can a patient with dysphagia symptoms request to have a dilation?   [19:28] Dr. Beveridge says, right before an endoscopy, she discusses it with the patient and gets consent. She asks, even if their symptoms are good, but in the endoscopy she sees a narrowing where she would recommend a dilation, if they're OK with that.   [20:05] Dr. Beveridge says, if they're having issues with swallowing, often she will ask if they're OK with her doing a dilation. If she sees a narrowing, she can focus on that area and dilate it.   [20:19] Dr. Beveridge says not everywhere in the esophagus can we see as well. The very beginning of the esophagus is challenging to see and challenging to evaluate on imaging.   [20:32] Dr. Beveridge talks about empiric dilation. You don't see a narrowing, but you want to rule it out, so you do a dilation at a safe size, like 16 or 18 mm, to make sure you're not missing something up high.   [20:58] Dr. Beveridge says she always talks about that with her patients. Most say, go ahead. Some patients definitely want dilation; other patients say no, they really don't.   [21:12] Dr. Beveridge then asks the patient if there's real narrowing that may cause a food impaction, would they want dilation then, or hold off for another day?   [21:30] Dr. Beveridge never wants to do something the patient is not comfortable with. She also doesn't want them to need another endoscopy unnecessarily, if she can avoid that for them in the moment.   [21:46] Dr. Beveridge mentions the BougieCap used in Europe. It's a cap you put at the end of the endoscope. You use your endoscope as the dilator. You watch the whole time. It is hard plastic that causes a nice dilation. We may see it come to the U.S.   [22:37] Dr. Beveridge speaks of the FLIP catheter, which is a catheter with a balloon that doesn't cause dilation but distends and helps measure the diameter.   [23:33] Holly asks if Dr. Beveridge gives tips to patients on how to prepare for dilation and the recovery process.   [23:49] Dr. Beveridge had an upper endoscopy. She says there's nothing like experience to understand it better. She didn't have a dilation, but the biopsies caused discomfort.    [24:21] Dr. Beveridge says a lot of her patients have been through upper endoscopies, so they know how it feels. She warns them that the biopsies and dilation can cause discomfort.   [24:33] What's challenging is that everyone is different. Some patients are going to be more hypersensitive to it, and other patients are going to say they felt nothing and they were fine.   [24:46] Dr. Beveridge says some patients need to modify their diet for a few days to avoid significant chest pain. You never want someone to have to go to the ER for significant chest pain when it will just heal over time, and there's no perforation.   [25:12] Dr. Beveridge says other patients will be like her, eating chips and pretzels and saying they're fine. Dr. Beveridge typically has them start with liquids, nothing too hot or too cold, and advance as tolerated.   [25:28] Dr. Beveridge says patients can always use TylenolⓇ and over-the-counter numbing agents. You'll still have patients who will get significant discomfort. For the most part, starting with liquids has worked for Dr. Beveridge's patients.   [25:44] Holly recommends over-the-counter when her patients call, after she talks to their GI. Holly says after she has an endoscopy, she starts on liquids and shakes. On day three, she's fine. Holly says individualized care is amazing. We all are different.   [26:14] In the pediatric setting, the parents get the counseling, and they have not had sedation, but on the adult side, you're talking with the patient, who had sedation. Sometimes they don't remember.   [26:40] Dr. Beveridge says when possible, she waits for family members to come back and tells them they're going to have to "be the memory" because the patient probably won't remember this conversation.   [26:55] If a patient says no, they don't want them to come back and hear about it, always respect that. But Dr. Beveridge always tells them, you may not remember what we say.   [27:30] Ryan asks about data on how many times someone may need dilations. Dr. Beveridge says it comes down to the patient, but the biggest issue can be uncontrolled inflammation.   [27:44] Dr. Beveridge says if a patient's EoE is not controlled, inflammation leads to continued scarring down. That's why we talk about dilation as being an adjunctive measure, but not a treatment for EoE. It doesn't do anything for the inflammation.   [28:03] Dr. Beveridge says she has patients who ask why she can't just do a dilation every now and then. Dr. Beveridge considers dilation to be safe when needed, but if you can avoid it, that would be nicer for everyone.   [28:21] Dr. Beveridge says there's no great data on whether you only need one, or whether you're going to need 10, but one big theme is just: have we gotten your inflammation under control? That's also true for other conditions, such as acid reflux.   [28:45] Holly wasn't diagnosed until she was in her mid-twenties, and she had several upper endoscopies as a teenager and college student to dilate her, to help the situation.   [29:17] Holly says she had to get more endoscopies to figure out her weird food triggers that are not typical for everybody, so even if she's treated, she still has inflammation. That's why she had so many upper endoscopies.   [29:30] Ryan talks about underlying issues causing inflammation. Dilation is not treating those underlying causes. It's just helping with one symptom of this dysphagia, by expanding the esophagus.   [29:50] Ryan asks, What changes in symptoms should patients expect after the dilation? Dr. Beveridge says, ideally, if there's been a stricture, you're going to start to feel like your swallowing is better. You can get pills and food down better.   [30:07] Dr. Beveridge says, immediately post-dilation, sometimes people feel a little bit worse. Everything you swallow may be uncomfortable for you. But if it's been a successful dilation, hopefully, you're going to feel that things are going down better.   [30:40] Holly says she is so grateful that Dr. Beveridge looked into this, and hopefully, there will be a new protocol in the future. Holly asks what other key takeaways from this research may interest Dr. Beveridge in researching something further.   [31:02] Dr. Beveridge says, making sure that we're not missing scar tissue is big and important. One thing that we're trying to look at with our Pediatric GI colleagues is what threshold we should be looking at for the pediatric patient population.   [31:19] Dr. Beveridge says a pediatric patient's esophagus is a different size than an adult patient's. Understandably, we are more cautious when doing a dilation in the pediatric patient population than we are with adults.   [31:34] Dr. Beveridge may recommend empiric dilation for an adult but will feel more cautious about that with pediatric patients than with adult patients. Understanding what that threshold should be for the pediatrics is going to be really interesting.   [31:57] Dr. Beveridge says the diameter threshold we discussed is going to be important to know about, but everyone is different. You may have a diameter of 14 mm, you feel fine, and you don't want a dilation; you can accommodate OK. That's reasonable.   [32:15] Dr. Beveridge says she has had patients who get up to 18 mm, and that helps them, but they need a little bit more. If someone needs more of a dilation, we do that. Yes, have a threshold to assess, but always assess for what's personal for your patient.   [33:04] Dr. Beveridge says not just to assess the luminal diameter, but a thing that is helpful for gastroenterologists to know will be if there are other factors at play. As in her study of dysphagia predictors, anxiety, depression, and hypervigilance can play roles.   [33:37] Dr. Beveridge has patients who have to have a critical narrowing for them to finally feel an issue. Other patients, if they have the slightest of narrowing, are feeling something. Some patients are just more vigilant of what's happening in their esophagus.   [34:07] Dr. Beveridge says there's definitely a role for asking if your anxiety is under control. If there's feedback in the nerves, should we ask your GI Psychologist to be involved in terms of CBT for your esophagus? Take a look at everything.   [34:27] Dr. Beveridge says another part of the study they looked at was: are there different thresholds of eosinophils that we should be looking at? Is it just less than 15, or do some patients need it to be lower? Less than six? Less than 10?   [34:43] Dr. Beveridge says look at it as a whole for your patient.   [34:53] Dr. Beveridge says next, she will be working on a very long-term project: Can we identify a non-invasive method of screening a patient, diagnosing a patient for EoE, or monitoring a response to therapy?   [35:13] Dr. Beveridge has looked at transnasal endoscopy, which is put into this category of minimally invasive. It's still invasive; you're putting a scope through someone's nose, but it doesn't require sedation, which is a nice thing for some patients.   [35:29] There's the EnteroTrack, which started in Colorado. A patient swallows a string, and it stays in their esophagus for an hour, and we look at the proteins to see if things are active or not active.   [35:45] Dr. Beveridge is also looking at the breath metabolome. If we breathe into a bag and take a look at all the volatile organic compounds that are in our breath, can we find a signature related to EoE?   [36:01] It's assessing about 100 different compounds, not looking at one in particular, but how the whole thing looks. What signature is there, based on looking at all the compounds?   [36:15] Dr. Beveridge presented some of that data at DDW and has a grant from the ACG to look at this and assess patients with and without EoE.   [36:33] Dr. Beveridge says further, doing longitudinal data of looking at patients once they've gotten into remission on treatment and seeing, do we then see a signature change?   [36:47] Dr. Beveridge says no one is under any illusion that endoscopies are going away. They will always be part of what we do in gastroenterology, but there are limitations: sedation, a full day away from work, nothing by mouth, and a driver, etc.   [37:04] If there are alternatives to help supplement that, it would be nice. One of the barriers for patients doing diet elimination is the number of endoscopies that are required. If there's a way to assess by breath if a food is a trigger, that would be good.   [37:32] Dr. Beveridge says that's the big thing she's looking at, but it will take years. It's not going to be a quick, easy one, but it's very interesting to take a look at.   [37:45] Holly speaks of how much treatment has changed since she was diagnosed. She has done all the scopes. She says this sounds amazing. She loves that people like Dr. Beveridge are thinking of how to make testing less invasive and more comfortable.   [38:12] Dr. Beveridge says another thing she is excited about is the transition of care. She recently did a survey and is analyzing the data to assess what the barrier is from the physician perspective in terms of helping our patients transition.   [38:40] Dr. Beveridge is also looking at doing a nice multi-center consensus to help this as well, led by Dr. Sophia Patel and Dr. Emily McGowan, who are fantastic in the EoE world, looking to see how we can make this better for our patients.   [38:58] Ryan says, with so much interesting work coming up, we'll have to have you back to chat about some of these additional projects. Everyone is super interested in less invasive stuff and better treatment pathways. Transition of care is an important part of that.   [39:11] Ryan appreciates Dr. Beveridge for joining the conversation and hopes to have her back on another episode so we can learn more about EoE and these different future research endeavors.   [39:20] For our listeners who would like to learn more about EoE today, you can visit apfed.org/EoE and check out the links in the show notes below. [39:27] If you're looking to find specialists who treat eosinophilic disorders, we encourage you to use APFED's Specialist Finder, available at apfed.org/specialist.   [39:36] If you'd like to connect with others impacted by eosinophilic diseases, please join APFED's online community on the Inspire Network at apfed.org/connections.   [39:46] If you have personally been impacted by eosinophilic disorders and are interested in sharing your experience, please check out apfed.org/shareyourstory.   [39:55] Ryan thanks Dr. Beveridge for joining us. This was a fun conversation and really insightful. Holly thanks APFED's Education Partners AstraZeneca, GSK, Sanofi, Regeneron, and Takeda for supporting this episode.   Mentioned in This Episode:   APFED on YouTube, Twitter, Facebook, Pinterest, Instagram Real Talk: Eosinophilic Diseases Podcast apfed.orgapfed.org/specialist apfed.org/connections Claire Beveridge, MD Cleveland Clinic Education Partners: This episode of APFED's podcast is brought to you thanks to the support of AstraZeneca, GSK, Sanofi, Regeneron, and Takeda.   Tweetables (Edited):   "I have loved the work that we've done [at the Cleveland Clinic]. It's been really nice to center everything on our EoE patients and have nice multidisciplinary care with speech-language pathologists, allergists, dietitians, pulmonologists, and everyone." — Claire Beveridge, MD   "It's a little crazy to think that it's only in the last few years that we have had FDA-approved medications for [EoE], and that we have been jerry-rigging asthma medications to treat our patients." — Claire Beveridge, MD   "On the whole, dysphagia means issues with swallowing. … It's a feeling of something getting stuck or something slowly moving down. There are also subtle symptoms that can happen." — Claire Beveridge, MD   "The goal of a dilation is to get a disruption because there's scar tissue we want to break open." — Claire Beveridge, MD   "I am looking at the breath metabolome. If we breathe into a bag and take a look at all the volatile organic compounds that are in our breath, can we find a signature related to EoE?" — Claire Beveridge, MD   Guest Bio: Claire Beveridge, MD, is a Staff Member in the Department of Gastroenterology and Hepatology and heads the Eosinophilic Esophagitis (EoE) adult clinic as well as the transition pediatric to adult EoE clinic. Dr. Beveridge's specialty interests include: EoE, Achalasia, Barrett's esophagus, GERD, esophageal swallowing disorders, and esophageal motility disorders.

Roughly half of the average American's daily calories now come from ultra-processed foods — and cutting them out changes how you feel faster than you'd expect. Nurse Doza breaks down five shifts that show up within weeks: steadier blood sugar and energy, a healing gut, lower inflammation, clearer thinking, and hunger hormones that finally reset. Learn what really separates processed from ultra-processed food, and why just two weeks of whole food can change everything. Featured Product: Boost by MSW Nutrition When you're riding the ultra-processed blood-sugar roller coaster, energy is the first casualty — the mid-afternoon crash, the brain fog, the reach for the next quick fix. Boost is the multivitamin you can actually feel: 2,500 mcg of methylated B12, a full multivitamin plus B-complex, electrolytes, and plant-based antioxidants including S-acetyl-L-glutathione. Clean, slow-release energy from one stick in water — no added sugar, no crash — so real food finally has a fair shot at steadying you out.

Send us Fan MailAn MRI, a phone call, and four words nobody wants to hear: “You have a perforated bowel.” Zach Koscuik was on the road to a comedy gig when Crohn's disease forced yet another hard pivot, adding to a 25-year history that includes perianal Crohn's, fistulas, abscesses, emergency surgeries, biologics, and three ileocolonic resections. We talk with him about what it's like to grow up sick, manage the stigma that makes people minimize inflammatory bowel disease, and keep showing up to school, work, and life when your body is always negotiating the nearest bathroom.Then the story takes a turn into the world of clinical trials and high-stakes medicine. Zach explains how severe disease and short bowel complications pushed his team toward an autologous stem cell transplant, a process that essentially wipes out and restarts the immune system. We get specific about the testing, chemo, isolation, and the surreal experience of being treated on a cancer floor without having cancer, plus the very real impact of insurance decisions that kept him hospitalized for 43 days.The payoff lands with the kind of news IBD patients barely let themselves hope for: a one-year follow-up colonoscopy that comes back completely clean. We also keep it honest about what remains, including motility issues, joint pain, and the mental aftershocks of medical trauma. Zach closes with a simple challenge for the Crohn's and colitis community: practice equal empathy, because two people can share a diagnosis and live totally different realities. If this conversation hits home, subscribe, share the episode with a friend, and leave a review so more people living with IBD can find it.Links: Find Zach on InstagramInformation on the stem cell trial that Zach didStem Cell Therapy clinical trial site- Clinicaltrials.govLet's get social!!Follow us on Instagram!Follow us on Facebook!Follow us on Twitter!

Understanding how values and communication styles differ across cultures is key to succeeding internationally. That’s why training in cross-cultural communication has become commonplace in the international business world. In this session, we’ll look at 6 dimensions of cross-cultural communication and their application to medical scenarios.

SPONSORED BY NURP Nurp is algorithmic trading designed specifically for busy professionals who don't have time to watch markets. Check out start.nurp.com/doctors  to learn more. --- What do heavy metal screams, UFC on the White House lawn, AI-generated Menopause Barbie, and colonoscopy cocktails have in common? Somehow... they're all part of this week's Doc Tales with Cocktails. Drs. Tim and May Hindmarsh take listeners on another unpredictable ride through music, medicine, culture, and internet absurdity. From discovering the incredible vocal talent of Spiritbox's Courtney LaPlante to debating why humans are fascinated by violence, the conversation bounces between hilarious stories and surprisingly thoughtful observations. They also react to the viral AI-generated Menopause Barbie, discuss the ever-changing world of colonoscopy prep (including the unforgettable Piña Colonata), and preview next week's conversation about the internet's latest manscaping craze. As always, expect laughs, strong opinions, medical insight, and plenty of cocktails.   In This Episode Discovering the incredible vocal range of Spiritbox vocalist Courtney LaPlante Why harsh metal vocals are far more technical than most people realize The UFC event on the White House lawn and the internet's reaction A discussion about violence, sports, patriotism, and culture AI-generated "Menopause Barbie" goes viral Colonoscopy prep horror stories—and the hilarious Piña Colonata cocktail Why every gastroenterologist seems to recommend a different bowel prep Preview of next week's "manscaping" discussion   Resources & Mentions Spiritbox Evanescence Courtney LaPlante Jenna McCarthy (Substack) Anne Marie McQueen Hot Flash Inc. Orme Water   Subscribe If you enjoy honest conversations about medicine, culture, health, and everything in between, be sure to subscribe, leave a review, and share the show with someone who appreciates keeping life BS Free. Follow BS Free MD for new episodes every week. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Gut Check: Philip Okafor, MD, on Health Care Disparities in Gastroenterology by Gastroenterology Learning Network

Send us Fan MailA ninth inning ballpark burger. Days of relentless diarrhea. Then blood. John Capodilupo's ulcerative colitis diagnosis didn't arrive slowly, it hit like a truck, and it sent him into a crash course on what living with IBD really demands. We talk through the early fear and uncertainty, the 28-day hospitalization, and the chaos of juggling treatment while also battling infections like C. difficile and CMV colitis. John also shares his experience with fecal microbiota transplant (FMT) for recurrent C. diff and why the microbiome still feels like one of the biggest unsolved stories in gut health.From there, we connect the dots between health data and better decisions. John helped build Whoop, the wearable built around continuous physiological tracking like heart rate variability and sleep, and he explains what longitudinal data can reveal about stress, recovery, and early warning signs. We dig into how sleep disruption and subtle body signals can show up before you're sure whether you're flaring or just paying the price for Taco Bell.Then we get into Throne, the smart toilet monitoring system John now co-leads as Chief Product Officer. Throne clips onto the toilet and uses computer vision and sensors to track stool and urine trends passively, aiming to reduce guesswork, improve symptom recall, and open the door to research like flare prediction, medication durability, and future screening signals such as blood detection for colon cancer. We also cover the “real life” questions: multi-user households, cleaning, cost, and a privacy approach built around de-identified data and opt-in research.If you're curious about ulcerative colitis, Crohn's, IBD tracking, gut health technology, or the future of smart toilets, listen now then subscribe, share with a friend, and leave a review.Links: Throne's websiteFun article about the founding of ThroneBuy Throne for $50 off!  or use code ListenToYourGutLet's get social!!Follow us on Instagram!Follow us on Facebook!Follow us on Twitter!

Edward Ryan is the director of global infectious diseases at Massachusetts General Hospital. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. E.T. Ryan, F. Qadri, and J.A. Lynch. Global Cholera-Control Efforts — Progress and Remaining Challenges. N Engl J Med 2026;394:2177-2180.

If you've tried medications, diet changes, fiber supplements, or other therapies for IBS-C and still aren't feeling better, you're not alone. Many people with irritable bowel syndrome with constipation (IBS-C) feel frustrated when symptoms persist despite treatment. But when treatments don't work, it may be time to take a closer look at what's really going on. In this episode of the Gastro Girl Podcast, Jacqueline Gaulin sits down with Dr. William D. Chey, world-renowned gastroenterologist  at the University of Michigan and President of the American College of Gastroenterology, to discuss what patients should do when IBS-C treatments fail. Dr. Chey explains why some patients continue to struggle, what conditions may be overlooked, and how to work with your healthcare provider to develop a more effective plan. In this episode, you'll learn: ✅ Why IBS-C treatments may not always work as expected ✅ When it's time to rethink your diagnosis ✅ The role of pelvic floor dysfunction and other overlooked conditions ✅ Questions to ask your healthcare provider ✅ How to take the next step toward better symptom control ✅ Why you don't have to settle for ongoing symptoms Whether you're newly diagnosed or have been living with IBS-C for years, this episode offers practical insights to help you move forward with confidence. Learn more at GastroGirl.com. This episode is sponsored by Ardelyx.  

If you've been feeling exhausted, tired, bloated, anxious, in pain, or just not like yourself, you need to hear today's episode. Today, Mel sits down with one of the most respected medical researchers in the world, gastroenterologist Dr. Brennan Spiegel, to uncover the overlooked, invisible force that's having a shocking impact on your energy, strength, gut health, mood, and every single cell in your body – even how fast your body ages.   Whether you're dealing with fatigue, back pain, swelling, digestion issues, or a heaviness in your body that you can't shake, Dr. Spiegel says these are all signs you shouldn't ignore.   Dr. Spiegel is a gastroenterologist and the director of Health Services Research at Cedars-Sinai Medical Center in Los Angeles, one of the leading medical centers in the United States. He is also a professor of medicine and public health at UCLA.  He trained at Cedars-Sinai and UCLA, and is a pioneering researcher in the areas of gut health, the usage of AI in medicine, and tools that help patients with pain, anxiety, and chronic illness.  He's the founding editor of the Journal of Medical Extended Reality and he served as Editor-in-Chief of the American Journal of Gastroenterology.  Dr. Spiegel has published more than 300 peer-reviewed scientific papers, his research has been cited 30,000 times, and he is the author of Pull: How Gravity Shapes Your Body, Steadies the Mind, and Guides Our Health. What Dr. Spiegel reveals will challenge the way you think about your body and, more importantly, give you a completely new, practical way to start feeling better immediately. And it may give you the words and the insight you've been missing to help your aging parents and other loved ones finally start feeling better, too.   By the end of this episode, you'll understand: -Why a “bendy” pinky might be a clue to what's going on in your gut -10 foods that boost serotonin production in your body -The most effective treatment for IBS - and it's probably not what you've tried -A quick way to notice how the force of gravity is showing up in your body -How to make yourself taller in just a few minutes -Why standing on one leg is linked to a longer life -How a weighted vest can change your posture almost immediately -A surprising reason rollercoasters feel unbearable for some people -What “gravity management” looks like in real life  -One small habit that can improve how your body handles gravity Dr. Spiegel says the powerful, invisible force shaping every moment of your life is one you can learn to work with – and he'll show you how.   This is one of those conversations that will change how you see your body, your health, and what it means to be fully alive. For more resources related to today's episode, click here for the podcast episode page:     If you liked the episode, check out this one next: Change Your Body & Your Life in 1 Month: 4 Small Habits That Actually Work.   Connect with Mel:     Order Mel's new product, Pure Genius Protein Get Mel's newsletter, packed with tools, coaching, and inspiration. Get Mel's #1 bestselling book, The Let Them Theory Watch the episodes on YouTube Follow Mel on Instagram  The Mel Robbins Podcast Instagram Mel's TikTok  Subscribe to SiriusXM Podcasts+ to listen to new episodes ad-free Disclaimer Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Welcome to this week's Midlife Minute. Today, I'm focusing on all the questions I received about gallbladder health, including HRT-provoking symptoms, supplements that improve gallbladder health, and evidence-based food interventions. IN THIS EPISODE, YOU WILL LEARN: Why the risk of gallstones and gallbladder inflammation increases during the menopause transition How estrogen and progesterone HRT have different effects on gallbladder functioning The differences in risk between transdermal and oral HRT How the progesterone in HRT can cause gallbladder issues in some women What TUDCA is, and how it supports gallbladder health The value of TUDCA for women who have had their gallbladders removed How various nutrients and supplements support bile flow and gallbladder health What can contribute to gallstone formation Connect with Cynthia Thurlow   Follow on X, Instagram & LinkedIn Check out Cynthia's website. Submit your questions to support@cynthiathurlow.com  Join other like-minded women in a supportive, nurturing community: The Midlife Pause/Cynthia Thurlow.  Purchase Cynthia's book, The Menopause Gut. Cynthia's Intermittent Fasting Transformation Book The Midlife Pause Supplement Line Gallbladder Research: Cabrera D, Arab JP, Arrese M. UDCA, NorUDCA, and TUDCA in liver diseases: a review of their mechanisms of action and clinical applications. Seminars in Liver Disease. 2019;39(4):397–404. doi:10.1055/s-0039-1696799  Vang S, Longley K, Steer CJ, Low WC. The unexpected uses of urso- and tauroursodeoxycholic acid in the treatment of non-liver diseases. Global Advances in Health and Medicine. 2014;3(3):58–69. doi:10.7453/gahmj.2014.017  Bai M, Yang L, Liao H, et al. Tauroursodeoxycholic acid improves nonalcoholic fatty liver disease by regulating gut microbiota and bile acid metabolism. Journal of Agricultural and Food Chemistry. 2024;72(41):22655–22668. doi:10.1021/acs.jafc.4c04630  Simon JA, Hudes ES. Relation of serum ascorbic acid to serum vitamin B12, serum ferritin, and kidney stones in US adults. *Archives of Internal Medicine.*1999;159(6):619–624. doi:10.1001/archinte.159.6.619  Walcher T, Haenle MM, Kron M, et al. Vitamin C supplement use may protect against gallstones: an observational study on a randomly selected population. BMC Gastroenterology. 2009;9:74. doi:10.1186/1471-230X-9-74  Tsai CJ, Leitzmann MF, Willett WC, Giovannucci EL. Long-term intake of dietary fiber and decreased risk of cholecystectomy in women. American Journal of Gastroenterology. 2004;99(7):1364–1370. doi:10.1111/j.1572-0241.2004.30281.x  Leitzmann MF, Stampfer MJ, Willett WC, Spiegelman D, Colditz GA, Giovannucci EL. Coffee intake is associated with lower risk of symptomatic gallstone disease in women. Gastroenterology. 2002;123(6):1823–1830. doi:10.1053/gast.2002.37085  Moerman CJ, Smeets FW, Kromhout D. Dietary risk factors for clinically diagnosed gallstones in middle-aged men — a 25-year follow-up study. Annals of Epidemiology. 1994;4(3):248–254. doi:10.1016/1047-2797(94)90099-x Association between dietary magnesium intake and gallstones: the mediating role of atherogenic index of plasma. Lipids in Health and Disease. 2024;23(1):82. doi:10.1186/s12944-024-02074-4  Pitt HA, Doty JE, Murphy MM, Schwarz MB. Progesterone alters biliary flow dynamics. Annals of Surgery. 1999;229(2):205–209. doi:10.1097/00000658-199902000-00008

In this episode, Dr. Ruscio breaks down the surprising gut and systemic benefits of NAC (N-acetylcysteine), including how it may help break down biofilms, support SIBO and H. pylori treatment, improve gut lining repair, boost nutrient absorption, and support glutathione, mitochondria, and brain health. You'll also learn when sustained-release NAC may be useful, how to dose NAC properly, and what side effects or cautions to keep in mind.   ✅ Start healing with us! Learn more about our virtual clinic:  https://drruscio.com/virtual-clinic/  

Inflammatory bowel disease (IBD) is a debilitating, lifelong condition that changes how people plan their entire lives. In this episode, KT Park, Global Head of Gastroenterology and Hepatology, and Seppi Lin, Head of OMNI Early Clinical Development, explore the complex biology behind IBD. They discuss the role of genetics, the gut microbiome, and an individual's environment, as well as the exciting future of "immune reset" therapies that could offer hope for people with IBD. Read the full text transcript at www.gene.com/stories/the-abcs-of-ibd

As I have said many times before, some podcast ideas come from REAL clinic encounters. In this episode, Dr Hanna V, our dedicated PGY1 on our call team, and I will answer TWO real questions which arose just today on morning rounds, on our service: 1. Does NORMOTENSIVE HELLP still need Mag Sulfate? And 2. Does an indwelling foley s/p iatrogenic bladder injury at CS require prophylactic antibiotic coverage for urinary infection? Yep: It's a BOGO sale on today's podcast- Buy ONE GET ONE! Listen in for details.1. Gestational Hypertension and Preeclampsia: ACOG Practice Bulletin, Number 222.Obstetrics and Gynecology. 2020. Committee on Practice Bulletins—ObstetricsGuideline2. Woudstra DM, Chandra S, Hofmeyr GJ, Dowswell T.SR. Corticosteroids for HELLP (Hemolysis, Elevated Liver Enzymes, Low Platelets) Syndrome in Pregnancy.The Cochrane Database of Systematic Reviews. 2010. 3. Joshi D, James A, Quaglia A, Westbrook RH, Heneghan MA.Liver Disease in Pregnancy. Lancet. 2010. Review4. Rimaitis K, Grauslyte L, Zavackiene A, et al.Observational. Diagnosis of HELLP Syndrome: A 10-Year Survey in a Perinatology Centre. International Journal of Environmental Research and Public Health. 20195. Reau N, Munoz SJ, Schiano T.Guideline Liver Disease During Pregnancy.The American Journal of Gastroenterology. 2022. 6. ACG Clinical Guideline: Liver Disease and Pregnancy.The American Journal of Gastroenterology. 2016. Tran TT, Ahn J, Reau NS.7. ACOG Practice Bulletin No. 195: Prevention of Infection After Gynecologic Procedures. Obstetrics and Gynecology. 2018. Committee on Practice Bulletins—Gynecology Guideline8. Niels Johnsen, Hunter Wessells, Krystal Archer-Arroyo, et al. Best Practices Guidelines Management of Gentiunrinary Injuries.American College of Surgeons (2025). 20259. Fletke KJ, Jeong DH, Herrera AV . Urinary Catheter Management. American Family Physician. 2024..

In this episode of Talk Nerdy, Cara is joined by neurogastroenterologist, and instructor of medicine at Harvard Medical School, Dr. Trisha Pasricha. They discuss her new book, You've Been Pooping All Wrong: How to Make Your Bowel Movements a Joy. Follow Trisha: @trishapasrichamd