Podcasts about Gastroenterology

Welcome to this week's Midlife Minute. Today, I'm focusing on all the questions I received about gallbladder health, including HRT-provoking symptoms, supplements that improve gallbladder health, and evidence-based food interventions. IN THIS EPISODE, YOU WILL LEARN: Why the risk of gallstones and gallbladder inflammation increases during the menopause transition How estrogen and progesterone HRT have different effects on gallbladder functioning The differences in risk between transdermal and oral HRT How the progesterone in HRT can cause gallbladder issues in some women What TUDCA is, and how it supports gallbladder health The value of TUDCA for women who have had their gallbladders removed How various nutrients and supplements support bile flow and gallbladder health What can contribute to gallstone formation Connect with Cynthia Thurlow   Follow on X, Instagram & LinkedIn Check out Cynthia's website. Submit your questions to support@cynthiathurlow.com  Join other like-minded women in a supportive, nurturing community: The Midlife Pause/Cynthia Thurlow.  Purchase Cynthia's book, The Menopause Gut. Cynthia's Intermittent Fasting Transformation Book The Midlife Pause Supplement Line Gallbladder Research: Cabrera D, Arab JP, Arrese M. UDCA, NorUDCA, and TUDCA in liver diseases: a review of their mechanisms of action and clinical applications. Seminars in Liver Disease. 2019;39(4):397–404. doi:10.1055/s-0039-1696799  Vang S, Longley K, Steer CJ, Low WC. The unexpected uses of urso- and tauroursodeoxycholic acid in the treatment of non-liver diseases. Global Advances in Health and Medicine. 2014;3(3):58–69. doi:10.7453/gahmj.2014.017  Bai M, Yang L, Liao H, et al. Tauroursodeoxycholic acid improves nonalcoholic fatty liver disease by regulating gut microbiota and bile acid metabolism. Journal of Agricultural and Food Chemistry. 2024;72(41):22655–22668. doi:10.1021/acs.jafc.4c04630  Simon JA, Hudes ES. Relation of serum ascorbic acid to serum vitamin B12, serum ferritin, and kidney stones in US adults. *Archives of Internal Medicine.*1999;159(6):619–624. doi:10.1001/archinte.159.6.619  Walcher T, Haenle MM, Kron M, et al. Vitamin C supplement use may protect against gallstones: an observational study on a randomly selected population. BMC Gastroenterology. 2009;9:74. doi:10.1186/1471-230X-9-74  Tsai CJ, Leitzmann MF, Willett WC, Giovannucci EL. Long-term intake of dietary fiber and decreased risk of cholecystectomy in women. American Journal of Gastroenterology. 2004;99(7):1364–1370. doi:10.1111/j.1572-0241.2004.30281.x  Leitzmann MF, Stampfer MJ, Willett WC, Spiegelman D, Colditz GA, Giovannucci EL. Coffee intake is associated with lower risk of symptomatic gallstone disease in women. Gastroenterology. 2002;123(6):1823–1830. doi:10.1053/gast.2002.37085  Moerman CJ, Smeets FW, Kromhout D. Dietary risk factors for clinically diagnosed gallstones in middle-aged men — a 25-year follow-up study. Annals of Epidemiology. 1994;4(3):248–254. doi:10.1016/1047-2797(94)90099-x Association between dietary magnesium intake and gallstones: the mediating role of atherogenic index of plasma. Lipids in Health and Disease. 2024;23(1):82. doi:10.1186/s12944-024-02074-4  Pitt HA, Doty JE, Murphy MM, Schwarz MB. Progesterone alters biliary flow dynamics. Annals of Surgery. 1999;229(2):205–209. doi:10.1097/00000658-199902000-00008

In this episode, Dr. Ruscio breaks down the surprising gut and systemic benefits of NAC (N-acetylcysteine), including how it may help break down biofilms, support SIBO and H. pylori treatment, improve gut lining repair, boost nutrient absorption, and support glutathione, mitochondria, and brain health. You'll also learn when sustained-release NAC may be useful, how to dose NAC properly, and what side effects or cautions to keep in mind.   ✅ Start healing with us! Learn more about our virtual clinic:  https://drruscio.com/virtual-clinic/  

Join us for an “In The Know” special edition where our experts discuss our Cystic Fibrosis Foundation-accredited program that is co-directed by a pediatric pulmonologist and a pediatric gastroenterologist, enabling our team of experts to provide all the services a child needs in one location. Learn more about our Cystic Fibrosis Program. 

Inflammatory bowel disease (IBD) is a debilitating, lifelong condition that changes how people plan their entire lives. In this episode, KT Park, Global Head of Gastroenterology and Hepatology, and Seppi Lin, Head of OMNI Early Clinical Development, explore the complex biology behind IBD. They discuss the role of genetics, the gut microbiome, and an individual's environment, as well as the exciting future of "immune reset" therapies that could offer hope for people with IBD. Read the full text transcript at www.gene.com/stories/the-abcs-of-ibd

Deirdre Tobias is an associate professor in the Department of Nutrition at the Harvard T.H. Chan School of Public Health and Brigham and Women's Hospital. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. D.K. Tobias and F.B. Hu. The 2025–2030 Dietary Guidelines for Americans — Progress, Pitfalls, and the Path Forward. N Engl J Med 2026;394:1969-1971.

Send us Fan MailFive years post J-pouch surgery sounds like a finish line, but our bodies do not read the brochure. We're together in person for a live catch-up with our favorite recurring guest and IBD Registered Dietitian, Stacey Collins, and we get real about what changes with time and what still blindsides you when you live with a J-Pouch after IBD.We talk through the wins that matter most day to day: more capacity, less urgency, and the quiet joy of doing normal things without panic, like waiting in line, taking long road trips, hiking, skiing, and traveling. Then we dig into the stuff patients whisper about but rarely get warned about, especially gas pain. We break down what it feels like, why it can block emptying, what actually helps (yes, including “toilet yoga”), and why travel, altitude, fasting, dehydration, carbonation, and food additives can make symptoms spike.We also cover the scary gray zones: when symptoms feel like a Crohn's flare but turn out to be SIBO, why antibiotics may be part of J-pouch life, and how to rebuild the gut microbiome afterward with food you can tolerate. Finally, we get blunt about the “surgery is curative” myth, the need for ongoing monitoring (iron deficiency anemia, B12, folate, fatigue), and what better post-op care should look like, including pelvic floor physical therapy and honest expectations at 3, 6, and 12 months.If you found this helpful, subscribe, share it with someone who needs it, and leave a review. What's one thing you wish your care team had told you before surgery?Links: Stacey's website- sign up for her waiting list, find resourcesStacey's additives guideStacey's oral rehydration guideInfo about SIBO- Mayo ClinicInfo about the ENIGMA Study- National Institutes of Health Info about the ENGIBMA Study from Stacey's websiteLet's get social!!Follow us on Instagram!Follow us on Facebook!Follow us on Twitter!

In this episode, Lin Chang, MD, and Jan Tack, MD, PhD, discuss the history and evolution of Rome criteria, developing guidelines for multifactorial disorders in Rome V and more. ·       Lin Chang, MD, and Jan Tack, MD, PhD 1:04 ·       How has the Rome Foundation evolved over the last ten years? 4:26 ·       What are the Rome criteria, and why should clinicians care about them? 7:20 ·       How did these guidelines become the Rome criteria? 10:32 ·       What is the timeline of developing these criteria? 12:35 ·       Can you tell us about how the Rome Foundation got to the name "DGBI", and why it makes sense for multifactorial conditions? 22:22 ·       What are the highlights and most important changes from Rome V?  26:38 ·       How will this information be disseminated so clinicians can learn about it? 34:22 ·       What lessons did you learn from the Rome V process? 37:40 ·       What's next for the Rome Foundation? 40:04 Lin Chang, MD, is professor of medicine and vice chief of the Vatche and Tamar Manoukian Division of Digestive Diseases at David Geffen School of Medicine at UCLA. Jan Tack, MD, PhD, is president of the Rome Foundation. He also serves as professor of medicine at KU Leuven and chief of the division of gastroenterology and hepatology at Leuven University Hospitals. We'd love to hear from you! Send your comments/questions to guttalkpodcast@healio.com. Follow us on X @HealioGastro @sameerkberry @umfoodoc. Disclosures: Chey and Tack report no financial disclosures. Chang reports consulting roles with Ardelyx, Atmo, Eli Lilly & Co., FoodMarble, GSK, Ironwood Pharmaceuticals and Ono Pharmaceutical; speaking fees from Bausch Health; research grants from AnX Robotica and Ironwood; serving on the Rome Foundation Board of Directors; and having unvested stock options with FoodMarble, ModifyHealth, PICO Health and Trellus Health. Reference: ·        Drossman DA, et al. Gastroenterology. 2026;doi:10.1053.j.gastro.2026.02.014.

Did you know one third of IBS-D cases could be triggered by bile acids in the large intestine? This week's interview is with Prof Bu'Hussain Hayee and helps explain all you need to know:What is bile acid diarrhoea?The effect of diets on bile acidsAsking your GP about whether this could be causing your IBS-DProfessor HayeeProfessor Hayee has been a Consultant Gastroenterologist at King's College Hospital since 2011. He has held Lead roles for the Inflammatory Bowel Disease service and endoscopy Training Lead and is now the Director for the Division of Liver, Gastroenterology and Endoscopy. He served as Director for the London Endoscopy Academy (2021-23) and is a member of the British Society of Gastroenterology Council, and a Fellow of the American Society of Gastrointestinal Endoscopy. He maintains an active role in basic science, endoscopic and clinical research as well as teaching internationally. His PhD, awarded in 2010, focussed on the gut immune system and Crohn's disease and he maintains an interest in gut health and immunity, treating people with a variety of long-term digestive problems through NHS and private practice.Buy my book - Inside Knowledge for people with IBS & SIBO (find it on Amazon)Get free weekly IBS & SIBO emails - https://mailchi.mp/goodnessme-nutrition.com/h6acndd1bsWork with me3 month Gut Reset - https://www.goodnessme-nutrition.com/consultations/Ready for your gut reset?

Co-hosts Ryan Piansky, a graduate student and patient advocate living with eosinophilic esophagitis (EoE) and eosinophilic asthma, and Holly Knotowicz, a speech-language pathologist living with EoE who serves on APFED's Health Science Advisory Council, interview Dr. Chukwuemeka Oko, MD, MBA, on clinical trials. Disclaimer: The information provided in this podcast is designed to support, not replace, the relationship between listeners and their healthcare providers. Opinions, information, and recommendations shared in this podcast are not a substitute for medical advice. Decisions related to medical care should be made with your healthcare provider. Opinions and views of guests and co-hosts are their own.   Key Takeaways: [:49] Co-host Ryan Piansky introduces this episode, brought to you thanks to the support of Education Partners GSK, Sanofi, Regeneron, and Takeda. Ryan introduces co-host Holly Knotowicz.   [1:13] Holly introduces today's topic — clinical trials — and today's guest, Dr. Chukwuemeka Oko, a Clinical Research and Medical Affairs Professional supporting Duke University Hospital's Department of Gastroenterology and Transplant Hepatology.   [1:33] Dr. Oko explains that he is sharing general, educational information from his perspective and experience, not speaking on behalf of Duke University, nor any industry sponsor, nor any company he has worked for.   [1:50] Dr. Oko's goal today is to help the listeners feel clearer, more confident, and more in control when they are thinking about clinical research.   [2:29] Dr. Oko's work sits mainly at the intersection of clinical research and medical affairs. He helps translate evolving science into practical, patient-centered decisions.   [2:40] From an academic standpoint, he supports clinical trials and evidence generation from feasibility through education.   [2:49] Dr. Oko also engages investigators and thought leaders from industry sponsors in scientific exchanges that lead to insights, study design, and real-world care pathways.   [3:03] Dr. Oko had two reasons to study eosinophilic esophagitis and eosinophilic disease. The first is the patient journey and biology.   [3:11] On the patient side, many people spend a long time seeking answers. Sometimes they feel dismissed before they get a clear diagnosis and a plan that fits their life.   [3:24] On the biology side, eosinophilic disease teaches us a lot about how our immune signals can drive information differently across tissues like the esophagus and airways.   [3:40] Dr. Oko supported an EoE study experience with an industry sponsor in the past. The best research doesn't just test; it helps patients and clinicians make clearer decisions.   [4:12] Dr. Oko explains that a clinical trial is a carefully designed, carefully crafted study in people that answers specific medical questions, most often about safety, effectiveness, or dosing of the study drug or how a treatment should be used.   [4:32] A key structure of a study is a written protocol where safety monitoring is in place, and the defined outcome or results are very reliable. The FDA always oversees clinical trials in the U.S.    [4:44] Dr. Oko often describes a trial as a highly-monitored learning system. It's how medicine moves from "We think this might help" to "We know what helps, for whom, and also at what risk."   [5:09] Dr. Oko says clinical trials usually study what improves patient outcomes, for whom, and at what risk, using methods that we can trust. Trials may evaluate new medicines, devices, dosage strategies, or even procedures.   [5:31] Clinical trials can also study non-drug approaches such as diet interventions, symptom tracking, monitoring tools, and education strategies.   [5:44] Many trials have also included biomarkers, or signals in the blood or tissue, helping to support an EoE diagnosis so that the patients can get treated in an early and effective manner.   [6:36] Dr. Oko says patients sometimes ask him if they are guinea pigs. In reality, trials are heavily regulated and closely monitored, with strict safety reporting requirements. Participants are not guinea pigs.   [7:06] Dr. Oko also hears patients ask if they are "stuck" once they join the clinical trial. No, a trial is a completely voluntary participation, and they can withdraw at any time.   [7:25] Other patients ask if trials are only for people who are out of options. Many trials are designed for earlier stages, especially when the goal is to prevent complications or reduce steroid exposure.   [7:46] The last question Dr. Oko hears a lot is "Will I be in the placebo group?" He says it's an understandable fear. They are asking if they will go untreated in the placebo group.   [8:29] In many trials, a placebo is not the same as "no care". Often, the participants continue the standard-of-care treatment, and the study drug or placebo is added to the standard-of-care treatment.   [8:45] Trials typically involve symptom monitoring and a plan for what happens if the symptoms worsen. There are exit criteria.   [9:01] From the pharmaceutical side, it's the end of treatment once you decide to voluntarily exit the study.   [9:10] Dr. Oko's advice is, if you participate, ask the study team physicians to explain in plain language what you'll receive, what you can continue, and what happens if you flare up. Clear answers are always a part of ethical research.   [10:33] Holly asks what it means to participate in a Phase 1, Phase 2, or Phase 3 trial. Dr. Oko says a Phase 1 trial is focused mostly on the safety and the dosing regimen. It's usually a small group of five to 100 or so.   [10:52] A Phase 2 trial always looks for the drug's effectiveness and continues monitoring safety. It's usually a group of 100 to 300 subjects. They look for meaningful signals of the outcomes derived from the trial.   [11:10] A Phase 3 trial is usually large. It's multi-centered. It's called a complementary study. It involves thousands of patients. It can even be across nations and states.   [11:26] This is where they compare new interventions against a placebo or against a standard of treatment to provide clinical benefits and support for regulatory approval.    [12:03] Participating in any phase of a trial includes fitting the eligibility criteria of inclusion for that particular phase. If you are a good match, you can be in either a Phase 1, Phase 2, or Phase 3 trial.   [12:52] Holly says she knows that a lot of people with EoE or EGIDs are very curious about trials and how to participate in them.   [13:00] Ryan says we have a very active patient community, and everyone's looking for ways to get involved in research and new diagnostics or medications to improve their own outcomes and help everyone else.   [13:35] Dr. Oko says the benefits of participating in a clinical trial include access to potentially disease-modifying therapies years before they reach the market.   [13:47] Another benefit is extraordinarily close medical monitoring. When you're in a clinical trial, you have more frequent visits and more frequent labs than usual.   [14:01] Endoscopies are out of the normal standard of care, but will be more frequent than normal to analyze the efficacy of the study drug.   [14:11] Dr. Oko says one of the risks is the unknown side effects the study drug comes with, because we are still understanding the biology.   [14:21] The time commitment for visits can be more than typical for a patient, especially if there is a long travel time involved. Patients may arrive at 7:00 or 8:00 a.m. They may need to find a place to live nearby, depending on the pace of the trial.   [14:57] Holly lives in Maine, and a lot of the trials are in Boston. It's a lot of travel. For people with any kind of chronic illness, all we think about is money. Holly asks if people pay to be part of a clinical trial.   [15:25] Dr. Oko states that the patients do not have to pay anything to be part of a clinical trial. Patients do get compensated by the trial sponsor for travel, accommodation, parking, and a meal for the days they are onsite.   [16:33] Dr. Oko says that patients tend to bring up insurance. It is a misconception that the study will pay for their standard-of-care medication during the study. Patients need to ask the study team what insurance will pay for and what the study will pay for.   [16:59] Dr. Oko says the insurance usually covers the regular standard-of-treatment, but any other additional treatment, procedures, and visits are all covered by the study sponsor.    [17:29] The study sponsor may ask for an endoscopy to be done six months before the study to determine eligibility for the study. If it is done within a year, the study sponsor will determine if you are qualified. That is part of the eligibility criteria in some cases.   [18:26] Dr. Oko tells patients to always ask questions, like what the schedule of events is in the clinical trial.   [18:35] The schedule of events tells you how many visits are required for you to be part of this study. They will list the activities to be done. They will list the labs you will need at what week. They will list when you need endoscopies, at week one and later.   [19:05] If you exit from the study, if you don't want to participate anymore, you are still required to come on site just to make sure that you are in good shape. Those are called formal visits.   [10:29] Dr. Oko explains that formal visits are necessary for the patient's safety and to make sure that the data points collected in the study will be effective.   [20:01] Patients enrolling in a clinical trial can also ask about the known risks of the symptom monitoring plan. They can ask what is covered and what is not covered by insurance, and what will be considered out of pocket.   [20:20] If patients are in the placebo group, what will happen if symptoms worsen? In the protocol, there is always a rescue plan. If a symptom flares up, the Principal Investigator carries out the rescue plan.   [20:58] The study team is available on a 24/7 hotline. The questions you ask are very important. No question is too small to ask. Every question and every symptom you report is important. You can withdraw at any time, and there is always a follow-up.   [22:19] Dr. Oko says the trial data that has already been collected from part of our eosinophilic studies has led to various FDA approvals of the biologics. We are working  to try to transform EoE from a steroid-dependent or diet-only disease into a position of long-term control.   [22:37] Trial findings have shaped care, expanding evidence-based options, clarifying which patients benefit the most, and improving how we measure our outcomes, the symptoms, and quality of life, as measured by patients' quality-of-life surveys.   [23:06] Quality-of-life surveys are very important for the study team. They help to measure safety, too. The evidence generated from this data leads to insights and improves study design, protocol design, and ultimately, improves patient care.   [23:40] Ryan says the community is interested in clinical trials because they benefit patients, researchers, and clinicians. We're thankful for the clinicians and researchers putting in all the work to make these clinical trials happen.   [24:01] Ryan adds, we're also thankful for the patients who are interested in these trials. For patients who are looking to participate, how can they find clinical trials to participate in and join?   [24:15] Dr. Oko says people can find the website ClinicalTrials.gov. It's an important tool in looking for various clinical research. Scientists are recruiting at a given time. You can use the Advanced Search option to narrow the search by state and criteria.   [24:54] You can always discuss clinical trials with your primary care physicians. You can look for major academic medical centers. Most of them always have clinical research studies going on.   [25:07] Dr. Oko says APFED.org is a very good tool. It always maintains up-to-date trial listings and patient-friendly summaries where patients can read about the studies.   [25:30] Ryan says he's very appreciative of the mention of APFED. There is a link on APFED.org so people can find studies. There are clinical trials listed that people can research more and join.   [25:46] Holly asks Dr. Oko to share advice for listeners who are considering participating in a clinical trial. He shares, "I want each one of you to approach the decision with the same care you would with any major medical choice. Review the Informed Consent Form (ICF)."   [26:23] "The word informed means you should be informed. It's your right to get informed with every line, every detail. The Consent Form can be 30 pages long, but please just know that you are not in a rush to answer."   [26:43] "You can take the Consent Form and discuss it with your friends, your family, your primary care physician, your gastroenterologist, and your allergist and get more information."   [27:00] "When you join an interventional trial, or a registry, your contribution accelerates the science and benefits the entire eosinophilic community."   [27:12] "From my years of reviewing medical charts and supporting new recruitments, I feel patients feel most satisfied when they are fully informed and genuinely partnered with the study team. That's how I partner with the patients. I am always there to help."    [27:40] Ryan says that is great advice for patients, and hopefully, some of our listeners to this episode will go out there and look for clinical trials to participate in or ask their physicians, next time they're getting care.   [27:52] For patients who would like to know more about eosinophilic disorders, we encourage you to visit APFED.org and check out the links in the show notes below, specifically to research opportunities listed on APFED.org. [28:08] If you've been personally impacted by eosinophilic disorders and are interested in sharing your experiences, we encourage you to please check out APFED.org/shareyourstory.   [28:17] Ryan thanks Dr.Oko for joining us today. This was really helpful and insightful, and hopefully, we'll have many new patients interested in joining clinical trials. Dr. Oko thanks Ryan and Holly for having him on and thanks every listener who has joined us.   [28:33] Dr. Oko says it has been a genuine pleasure and privilege for him. He has spent years seeing patients, reviewing their charts, and hearing their stories. We see you, we hear you. Science is advancing rapidly and shaping outcomes. You are not alone.   [30:17] Holly thanks Dr. Oko for his research and clinical trials, and thanks APFED's Education Partners GSK, Sanofi, Regeneron, and Takeda for supporting this episode.   Mentioned in This Episode:   APFED on YouTube, Twitter, Facebook, Pinterest, Instagram Real Talk: Eosinophilic Diseases Podcast Apfed.org apfed.org/specialist apfed.org/connections apfed.org/research/clinical-trials Duke University Hospital's Department of Gastroenterology Education Partners: This episode of APFED's podcast is brought to you thanks to the support of GSK, Sanofi, Regeneron, and Takeda.   Tweetables:   "Many people spend a long time seeking answers. Sometimes they feel dismissed before they get a clear diagnosis and a plan that fits their life." — Chukwuemeka Oko, MD, MBA   "On the biology side, eosinophilic disease teaches us a lot about how our immune signals can drive information differently across tissues like the esophagus and airways." — Chukwuemeka Oko, MD, MBA   "In many trials, a placebo is not the same as no care. Often, the participants continue the standard-of-care treatment, and the study drug or placebo is added to the standard-of-care treatment." — Chukwuemeka Oko, MD, MBA   "I tell patients to always ask questions, like what the schedule of events is in the clinical trial." — Chukwuemeka Oko, MD, MBA   "[If a patient exits the study], formal visits are necessary for the patient's safety and to make sure that the data points collected in the study will be effective." — Chukwuemeka Oko, MD, MBA   "From my years of reviewing medical charts and supporting new recruitments, I feel patients feel most satisfied when they are fully informed and genuinely partnered with the study team." — Chukwuemeka Oko, MD, MBA   Guest Bio: Chukwuemeka Oko, MD, MBA

Editor's Choice:  Optimization of methylated DNA markers to rule out endometrial cancer in patients with abnormal uterine bleedingEditorial: Tampon-based methylated DNA testing for endometrial cancer: Promising innovation, but prudence before practiceHosted by: Charles N. Landen Jr., MD; University of Virginia Charlottesville, VA, USAFeaturing: Jamie N. Bakkum-Gamez, MD; Department of Obstetrics and Gynecology, Mayo Clinic, Rochester, MN, USAJohn B. Kisiel, MD; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USAJoy M. Davis MD; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, USACheck out more content on the journal's homepage  at https://www.gynecologiconcology-online.net

Send us Fan MailThe word “surgery” can feel like a threat when you're young and already worn down by Crohn's disease. Michael Morgan, author of *The Secret Life of Crohn's*, joins us to talk about being diagnosed at age 10, cycling through medications, and living with the kind of urgency that forces you to plan every minute around toilets, school schedules, and the fear of being noticed. We get into the part people don't always see: the constant anxiety, the shrinking world, and how much mental energy IBD can steal long before anyone calls it mental health.Michael also shares what it was like to hear ostomy surgery discussed as a teenager, the misconceptions that fueled his fear, and the moment he realized life on the other side could be bigger than the life he was trying to protect. We talk about the adjustment period, confidence building, and why so many people with ostomies describe freedom and relief once their disease is under better control.From there, we dig into practical realities: asking schools for accommodations, using tools that make bathroom access easier, staying on top of Crohn's management even after major surgery, and navigating rare symptoms like inflammatory disease in the mouth. And yes, we go deep on travel with an ostomy, including packing supplies, hostel bathrooms, and the small “tricks” that make big adventures possible.If you're facing a big treatment decision, supporting a child with IBD, or trying to make your world bigger again, this conversation will meet you where you are. Subscribe, leave a review, and share this with someone who needs a little more hope and a lot more real talk.Links: More of Michael's Story- Crohn's & Colitis UKOrder Michael's bookArticle about Michael and his book- Hackney CitizenTraveling with an ostomy- United Ostomy AssociationLet's get social!!Follow us on Instagram!Follow us on Facebook!Follow us on Twitter!

What is cultural distress? It is a negative response rooted in a cultural conflict where the patient lacks control over their situation. It results in more physiologic effects on the body resulting in allostatic overload. To prevent this, healthcare practitioners must use strategies such as cultural humility to help patients navigate healthcare. Come find the best ways to deliver culturally sensitive care in any setting.

As I have said many times before, some podcast ideas come from REAL clinic encounters. In this episode, Dr Hanna V, our dedicated PGY1 on our call team, and I will answer TWO real questions which arose just today on morning rounds, on our service: 1. Does NORMOTENSIVE HELLP still need Mag Sulfate? And 2. Does an indwelling foley s/p iatrogenic bladder injury at CS require prophylactic antibiotic coverage for urinary infection? Yep: It's a BOGO sale on today's podcast- Buy ONE GET ONE! Listen in for details.1. Gestational Hypertension and Preeclampsia: ACOG Practice Bulletin, Number 222.Obstetrics and Gynecology. 2020. Committee on Practice Bulletins—ObstetricsGuideline2. Woudstra DM, Chandra S, Hofmeyr GJ, Dowswell T.SR. Corticosteroids for HELLP (Hemolysis, Elevated Liver Enzymes, Low Platelets) Syndrome in Pregnancy.The Cochrane Database of Systematic Reviews. 2010. 3. Joshi D, James A, Quaglia A, Westbrook RH, Heneghan MA.Liver Disease in Pregnancy. Lancet. 2010. Review4. Rimaitis K, Grauslyte L, Zavackiene A, et al.Observational. Diagnosis of HELLP Syndrome: A 10-Year Survey in a Perinatology Centre. International Journal of Environmental Research and Public Health. 20195. Reau N, Munoz SJ, Schiano T.Guideline Liver Disease During Pregnancy.The American Journal of Gastroenterology. 2022. 6. ACG Clinical Guideline: Liver Disease and Pregnancy.The American Journal of Gastroenterology. 2016. Tran TT, Ahn J, Reau NS.7. ACOG Practice Bulletin No. 195: Prevention of Infection After Gynecologic Procedures. Obstetrics and Gynecology. 2018. Committee on Practice Bulletins—Gynecology Guideline8. Niels Johnsen, Hunter Wessells, Krystal Archer-Arroyo, et al. Best Practices Guidelines Management of Gentiunrinary Injuries.American College of Surgeons (2025). 20259. Fletke KJ, Jeong DH, Herrera AV . Urinary Catheter Management. American Family Physician. 2024..

Dr. John Pandolfino, Chief of Gastroenterology and Hepatology and Director of the Northwestern Medicine Digestive Health Institute, joins John Landecker to discuss a new technology Northwestern has been working on and developing that could allow doctors to make a “digital twin” of your body part to help with treatment.

Colorectal cancer is making headlines — and increasingly, it's affecting younger adults. Stephen Kucera, MD, Medical Director of Gastroenterology and Endoscopic Oncology, explains why diagnoses are rising in people under 55, what may be driving the trend, and the warning signs no one should ignore. He also shares the lifesaving steps everyone can take to reduce their risk, including when to get screened and how early detection can make all the difference. You can also watch the video recording on our Vimeo channel here. For more health tips & news you can use from experts you trust, sign up for Sarasota Memorial's monthly digital newsletter, Healthe-Matters.

Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Professor Amanda Muir from the Department of Gastroenterology, Hepatology, and Nutrition, The Children's Hospital of Philadelphia, and University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA, on the paper "FOXM1 inhibition reduces IL-13-induced epithelial remodelling and inflammation in eosinophilic oesophagitis" published in paper copy in Gut in May 2026. Please subscribe to the Gut podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/3UOTwqS) or Spotify (https://bit.ly/4rRJeUI).  

In this episode of Talk Nerdy, Cara is joined by neurogastroenterologist, and instructor of medicine at Harvard Medical School, Dr. Trisha Pasricha. They discuss her new book, You've Been Pooping All Wrong: How to Make Your Bowel Movements a Joy. Follow Trisha: @trishapasrichamd

In this episode of Bowel Sounds, hosts Drs. Amber Hildreth and Jennifer Lee talk to Dr. Elizabeth Rand, a pediatric gastroenterologist in the Division of Gastroenterology, Hepatology and Nutrition at Children's Hospital of Philadelphia (CHOP), Medical Director of CHOP's Liver Transplant Program, Director of the Gastroenterology Fellowship Program and Director of the Advanced Transplant Hepatology Program. We talk everything about Fontan Associated Liver Disease (FALD), from diagnosis to management and future research opportunities in the field. Learning objectivesDescribe the pathophysiology of FALDUnderstand the management challenges in patients with FALDExplore the unanswered questions about FALD to help guide future research priorities Links:Single-cell multiomics guided mechanistic understanding of Fontan-associated liver diseaseSend us Fan MailSupport the showThis episode may be eligible for CME credit!  Once you have listened to the episode, click this link to claim your credit.  Credit is available to NASPGHAN members (if you are not a member, you should probably sign up).  And thank you to the NASPGHAN Professional Education Committee for their review!As always, the discussion, views, and recommendations in this podcast are the sole responsibility of the hosts and guests and are subject to change over time with advances in the field.Check out our merch website!Follow us on Bluesky, Twitter, Facebook and Instagram for all the latest news and upcoming episodes.Click here to support the show.

A long-term patient of Palmerston North Hospital's gastroenterology department is concerned about the care he'll receive when the last permanent doctor leaves next month. Over recent years the service, which focuses on patients suffering from problems with their digestive systems, has struggled to attract specialists to work there. One left on Friday, and the other finishes in June. Temporary and locum doctors will fill the gaps, although Health NZ says it's sent out offers of employment to new recruits. Jimmy Ellingham reports.

Send us Fan MailMedical care can be doing everything “right” and you can still feel wrecked, anxious, and trapped in a never-ending cycle of symptoms, appointments, and fear. That gap is where GI psychology lives, and it's why we wanted Dr. Anna Katherine “AK” Black. AK is a licensed clinical health psychologist at GI Psychology, with a focus on gut-brain therapies, trauma-informed care, and medical fatigue in chronic illness.We get into what clinical hypnosis actually is (no stage tricks, no mind control) and why gut-directed hypnotherapy has decades of research behind it for GI conditions. AK explains the gut-brain connection in plain language, including how stress can hijack the system, how visceral hypersensitivity turns the volume up on sensations, and why you can't just tell your gut to “calm down” with conscious thoughts alone. We also talk about how fear and pain overlap, and why techniques that shift the nervous system toward parasympathetic regulation can change real physical symptoms.Then we name the thing so many people feel but rarely hear described: medical fatigue. If you've ever canceled yet another appointment, struggled to keep up with meds and procedures, or felt judged as “noncompliant,” this conversation puts words to that burnout and offers practical next steps. We also cover trauma-informed care, what providers can do with better language and screening, and why integrated teams work best. AK shares resources and explains the Crohn's & Colitis Foundation partnership group that combines community with skills like CBT and hypnosis.Subscribe for more real talk about living with IBD, share this with someone who needs it, and please leave a rating and review so more people can find the show. What part of the gut-brain story hit closest to home?Links: Join the IBD Psychotherapy GroupInfo on Gut-Directed HypnotherapyLet's get social!!Follow us on Instagram!Follow us on Facebook!Follow us on Twitter!

Javier Ampuero, MD, PhD - Making MASH a Priority in Our Gastroenterology Practices: Why We Should and How We Can

Javier Ampuero, MD, PhD - Making MASH a Priority in Our Gastroenterology Practices: Why We Should and How We Can

Javier Ampuero, MD, PhD - Making MASH a Priority in Our Gastroenterology Practices: Why We Should and How We Can

Javier Ampuero, MD, PhD - Making MASH a Priority in Our Gastroenterology Practices: Why We Should and How We Can

How Therapists Can Help Clients With IBS, Chronic Nausea, and Gut-Brain Disorders: An Interview with Dr. Ali Navidi, PsyD Curt and Katie talk with Dr. Ali Navidi, PsyD about disorders of gut-brain interaction, including IBS, chronic nausea, and other GI conditions that therapists may see more often than they realize. They explore how the gut-brain axis works, which clients may be more likely to struggle with these concerns, how therapists can stay within scope, and why specialized behavioral health treatment can directly improve symptoms rather than only helping clients cope with them. About Our GuestDr. Ali Navidi, PsyD is a licensed clinical psychologist and co-founder of GI Psychology, a national telehealth practice specializing in the treatment of gastrointestinal (GI) disorders and chronic pain. In addition to providing patient care, Dr. Navidi oversees clinical training and outreach initiatives at the practice. He has presented on GI disorders and chronic pain to organizations across the country, including the American College of Gastroenterology, UNC School of Medicine, George Mason University, Georgetown University (Grand Rounds), INOVA, as well as through podcasts, television appearances, and multiple State Academies of Nutrition and Dietetics. Key Takeaways Therapists are in a strong position to notice GI issues, especially in clients with anxiety, trauma histories, autism, or eating disorders. Disorders of gut-brain interaction are not just “in someone's head.” The pain and symptoms are real, even when there is no visible structural problem. Therapists should encourage appropriate medical evaluation and collaborate with gastroenterologists rather than trying to diagnose IBS or other GI disorders on their own. Specialized CBT and clinical hypnosis can directly treat gut-brain disorders, not just the anxiety that surrounds them. Dr. Navidi, PsyD describes a treatment model focused on hypervigilance, catastrophizing, and visceral hypersensitivity. When diet questions come up, therapists should be cautious and refer to GI-focused dietitians when appropriate. Therapists should also be careful about overconfident claims related to the microbiome, SIBO, and other popular gut-health conversations. For full show notes and the transcript for this episode, visit mtsgpodcast.com. Join the Modern Therapist Community Linktree: https://linktr.ee/therapyreimagined Patreon: https://www.patreon.com/c/mtsgpodcast Podcast Homepage: mtsgpodcast.com Facebook Group: https://www.facebook.com/groups/therapyreimagined Modern Therapist's Survival Guide Creative Credits Voice Over by DW McCann: https://www.facebook.com/McCannDW/ Music by Crystal Grooms Mangano: https://groomsymusic.com/

Today, we're diving into autoimmunity—what it actually is, why it happens, and how ultra-processed foods may be contributing to the problem. Autoimmune disease is often misunderstood. Some will tell you diet has nothing to do with it. Others claim diet is the cure. The truth is more nuanced—and that's exactly what we explore in this episode. You'll learn: What autoimmunity really is (and why it's a case of mistaken identity) How inflammation and the immune system interact The critical role of gut health and the microbiome How ultra-processed foods disrupt intestinal integrity and immune signaling Why stress and hyper-palatable foods create a harmful cycle A practical experiment you can try to see how diet impacts your own biomarkers This isn't about selling supplements or pushing extremes. It's about understanding the science so you can make informed decisions about your health. As always, this episode is backed by scientific literature. Full citations are included below, with abbreviated versions available on shorter clips. If you're dealing with autoimmune symptoms—or just want to better understand how food impacts your immune system—this episode is for you.   Full citation list: Hall KD, et al. “Ultra-Processed Diets Cause Excess Calorie Intake and Weight Gain: An Inpatient Randomized Controlled Trial of Ad Libitum Food Intake.” Cell Metabolism, 2019.     Supports the formulation argument: UPF intake increased spontaneous calorie intake and weight gain even with diets matched for presented calories, sugar, fiber, sodium, and macronutrients. This is your anchor for “hyper-palatability and formulation change physiology, not just psychology.”   Narula N, et al. “Association of Ultra-Processed Food Intake With Risk of Inflammatory Bowel Disease: Prospective Cohort Study.” BMJ, 2021.     Best human disease-level citation for the episode. Supports the claim that higher UPF intake is associated with greater IBD risk, making the gut-immune link clinically meaningful rather than purely theoretical.   Chassaing B, et al. “Randomized Controlled-Feeding Study of Dietary Emulsifier Carboxymethylcellulose Reveals Detrimental Impacts on the Gut Microbiota and Metabolome.” Gastroenterology, 2022.     Best emulsifier paper for human translation. Supports the claim that CMC can perturb the microbiota and metabolome and may contribute to barrier-hostile gut ecology in susceptible individuals.   Daniel N, et al. “Human Intestinal Microbiome Determines Individualized Responses to Dietary Emulsifier Carboxymethylcellulose.” Cellular and Molecular Gastroenterology and Hepatology, 2024.     Useful nuance paper. Supports the point that emulsifier sensitivity is not identical across all people and that host-microbiome context matters.   Shil A, et al. “Artificial Sweeteners Disrupt Tight Junctions and Barrier Function in the Intestinal Epithelium Through Activation of the Sweet Taste Receptor T1R3.” Nutrients, 2020.     Best citation for the “sugar-free does not mean barrier-neutral” point. Supports direct epithelial barrier effects of common artificial sweeteners in experimental models.   Peng L, et al. “Butyrate Enhances the Intestinal Barrier by Facilitating Tight Junction Assembly via Activation of AMP-Activated Protein Kinase in Caco-2 Cell Monolayers.” Journal of Nutrition, 2009.     Classic mechanistic citation for butyrate. Supports the claim that loss of fermentable fiber and reduced butyrate production can weaken barrier function.   Kumar KP, et al. “The Interplay Between the Microbiota, Diet and T Regulatory Cells in Maintaining Intestinal Homeostasis.” Frontiers in Microbiology, 2023.     Useful for the tolerance language. Supports the argument that diet and microbial metabolites shape Treg biology and mucosal tolerance.   Haase S, et al. “Sodium Chloride Triggers Th17 Mediated Autoimmunity.” Frontiers in Immunology, 2019.     Key citation for high salt and autoimmune-prone immune skewing. Supports the claim that excess salt can promote pathogenic Th17 biology relevant to autoimmune disease.   Wilck N, et al. “Salt-Responsive Gut Commensal Modulates TH17 Axis and Disease.” Nature, 2017.     Strong bridge between salt, microbiome, and Th17 signaling. Supports the point that salt is not just a blood pressure story; it is also an immune-story.   Vitales-Noyola M, et al. “Analysis of Sodium Chloride Intake and Treg/Th17 Lymphocytes in Patients With Rheumatoid Arthritis and Systemic Lupus Erythematosus.” Journal of Immunology Research, 2018.     Helpful human-facing citation for salt and immune skewing in autoimmune populations. Use cautiously, but it strengthens translation from theory to autoimmune terrain.   Phuong-Nguyen K, et al. “Advanced Glycation End-Products and Their Effects on Gut Health.” Nutrients, 2023.     Good review for the AGE section. Supports the argument that AGE-rich processed foods may worsen oxidative stress, microbiota balance, and barrier function.   Chen Y, et al. “Dietary Advanced Glycation End-Products Elicit Toxicological Effects by Disrupting Gut Microbiota and Increasing Colon Permeability in Rats.” Journal of Toxicology and Environmental Health, 2021.     Useful mechanistic support for the processing-chemistry section. Reinforces the claim that dietary AGEs can alter microbial ecology and increase permeability.   Monteiro CA, et al. “Ultra-Processed Foods: What They Are and How to Identify Them.” Public Health Nutrition, 2019.   Dr. Brendan McCarthy is the founder and Chief Medical Officer of Protea Medical Center in Arizona. With over two decades of experience, he's helped thousands of patients navigate hormonal imbalances using bioidentical HRT, nutrition, and root-cause medicine. He's also taught and mentored other physicians on integrative approaches to hormone therapy, weight loss, fertility, and more. If you're ready to take your health seriously, this podcast is a great place to start.  

Marcela Belleza, Tiago Arnaud e Flávio Barbieri discutem 5 armadilhas (erros) comuns em comunicação na prática médica e como evitá-las.Referências:1. Vogel D, Meyer M, Harendza S. Verbal and non-verbal communication skills including empathy during history taking of undergraduate medical students. BMC Med Educ. 2018;18(1):157. Published 2018 Jul 3. doi:10.1186/s12909-018-1260-9 2. Riess H, Kraft-Todd G. E.M.P.A.T.H.Y.: a tool to enhance nonverbal communication between clinicians and their patients. Acad Med. 2014;89(8):1108-1112. doi:10.1097/ACM.00000000000002873. Campos VF, et al. Comunicação em cuidados paliativos: equipe, paciente e família. Revista Bioética. 2019;27(4):711–804.  4. Patel AA, Arnold RM, Taddei TH, Woodrell CD. "Am I Going to Die?": Delivering Serious News to Patients With Liver Disease. Gastroenterology. 2023;164(2):177-181. doi:10.1053/j.gastro.2022.11.0065. Roter DL, Hall JA, Kern DE, Barker LR, Cole KA, Roca RP. Improving physicians' interviewing skills and reducing patients' emotional distress. A randomized clinical trial. Arch Intern Med. 1995;155(17):1877-1884.6. Fujimori M, Uchitomi Y. Preferences of cancer patients regarding communication of bad news: a systematic literature review. Jpn J Clin Oncol. 2009;39(4):201-216. doi:10.1093/jjco/hyn1597. Paladino J, Bernacki R, Neville BA, et al. Evaluating an Intervention to Improve Communication Between Oncology Clinicians and Patients With Life-Limiting Cancer: A Cluster Randomized Clinical Trial of the Serious Illness Care Program. JAMA Oncol. 2019;5(6):801-809. doi:10.1001/jamaoncol.2019.02928. James L. Hallenbeck. Intercultural differences and communication at the end of life, Primary Care: Clinics in Office Practice, Volume 28, Issue 2, 2001, Pages 401-413, https://doi.org/10.1016/S0095-4543(05)70030-0.9. Timothy Gilligan et al.  Patient-Clinician Communication: American Society of Clinical Oncology Consensus Guideline. J Clin Oncol 35, 3618-3632(2017). DOI:10.1200/JCO.2017.75.231110. Manual de cuidados paliativos / Maria Perez Soares D'Alessandro (ed.) ... [et al.]. – 2. ed. São Paulo: Hospital Sírio-Libanês; Ministério da Saúde, 2023.11. Forte DN, Stoltenberg M, Ribeiro SCDC, de Almeida IMMO, Jackson V, Daubman BR. The Hierarchy of Communication Needs: A Novel Communication Strategy for High Mistrust Settings Developed in a Brazilian COVID-ICU. Palliat Med Rep. 2024 Feb 9;5(1):86-93. doi: 10.1089/pmr.2023.0070. PMID: 38415076; PMCID: PMC10898234.

In this episode of Bowel Sounds, hosts Dr. Peter Lu and Dr. Jason Silverman talk to Dr. Leonel Rodriguez, Chief of Pediatric Gastroenterology and Professor of Pediatrics at Yale Medicine. We discuss the rising number of children presenting to us with the inability to belch and the relatively new diagnosis of retrograde cricopharyngeal dysfunction (R-CPD).Learning objectivesRecognize the presenting symptoms of retrograde cricopharyngeal dysfunction (R-CPD) and its potential overlap with disorders of gut-brain interaction.Understand the evaluation of a child with an inability to belch and the utility of esophageal manometry.Review the management of R-CPD, including the potential role of less invasive treatment options prior to cricopharyngeal Botox injection.Send us Fan MailSupport the showThis episode may be eligible for CME credit!  Once you have listened to the episode, click this link to claim your credit.  Credit is available to NASPGHAN members (if you are not a member, you should probably sign up).  And thank you to the NASPGHAN Professional Education Committee for their review!As always, the discussion, views, and recommendations in this podcast are the sole responsibility of the hosts and guests and are subject to change over time with advances in the field.Check out our merch website!Follow us on Bluesky, Twitter, Facebook and Instagram for all the latest news and upcoming episodes.Click here to support the show.

In this episode, I'm joined by Christina Jagielski, GI health psychologist and Clinical Assistant Professor in the Division of Gastroenterology and Hepatology at Michigan Medicine. Dr Jagielski specialises in the intersection of psychological trauma and gastrointestinal health, using evidence-based approaches such as cognitive behavioural therapy, acceptance and commitment therapy, relaxation training, and gut-directed hypnotherapy to support patients with a range of GI conditions. In this episode, we explore trauma-informed care in gastroenterology — including how trauma can shape gut symptoms, patient behaviour, and healthcare experiences. We unpack the biological and psychological pathways linking trauma and the gut–brain axis, the risk of re-traumatisation in clinical settings, and why patients with trauma histories often experience more severe symptoms and poorer quality of life. We also discuss practical strategies for clinicians and healthcare teams, including how to create safer, more compassionate environments through trauma-informed principles such as safety, transparency, choice, and collaboration. Whether you're a clinician, researcher, or someone living with a gut condition, this episode offers powerful insights into how care can be delivered in a way that heals, rather than harms. Please enjoy my conversation with Dr Christina Jagielski.

Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Professor Shanshan Wu from the Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, State Key Laboratory of Digestive Health, National Clinical Research Center for Digestive Disease, Beijing, China, and Professor Yuanjie Pang from Department of Epidemiology & Biostatistics, School of Public Health, Peking University, Beijing, China, on the paper "Long-term prognosis of lean MASLD: evidence from three population-based prospective cohorts" published in paper copy in Gut in April 2026. Please subscribe to the Gut podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/3UOTwqS) or Spotify (https://bit.ly/4rRJeUI).

Send us Fan MailA Crohn's diagnosis at eight can shrink a kid's world down to fatigue, fear, and the nearest bathroom. Nicole Thornton took that same reality and built something bigger: community, advocacy, and a blueprint for how young people with IBD can lead without pretending it's easy.We talk through Nicole's early health journey and the moment Camp Purple Live in New Zealand changed everything by giving her friends who truly understood Crohn's and colitis. From there, Nicole shares how she petitioned the New Zealand Parliament at just 12 years old to improve toilet access for people with inflammatory bowel disease and other urgent health needs, and how that effort evolved into the “I Can't Wait” campaign where businesses voluntarily welcome patients to use staff bathrooms. We also dig into the everyday stakes behind “bathroom access” and how stigma and public accidents can shape mental health, confidence, and relationships.Nicole also brings a global lens from her work with the International Federation of Crohn's and Ulcerative Colitis Associations (IFCCA) youth group, including what she's learned about medication access, healthcare funding, and how different countries support young patients. Finally, we get into why she's studying nursing, how small acts of care can change someone's life, and what it takes to balance advocacy, school, work, and chronic illness without burning out.If you care about Crohn's disease, ulcerative colitis, chronic illness advocacy, bathroom accessibility, or patient leadership, hit subscribe, share this with a friend, and leave a rating and review so more people can find the show.Links: Camp Purple Live- Crohn's & Colitis New ZealandIFCCA- Youth GroupArticle on Nicole's NZ parliamentary effortsStory on CCNZ on Nicole's trip to Brussels  Let's get social!!Follow us on Instagram!Follow us on Facebook!Follow us on Twitter!

Send us Fan MailThis week, I'm taking a curious, watch-and-see approach to GLP-1 medications—things like semaglutide, Ozempic, Wegovy. We'll cover the research-backed potential benefits, the side effects, what happens after stopping, and why the conversation is about much more than just weight. No judgment, no pressure, just information, reflection, and a reminder that your choices are personal and worth considering thoughtfully.Tune in if you want to explore GLP-1 medications from a place of curiosity and clarity.Quote of the Week:“We are what we repeatedly do. Excellence, then, is not an act, but a habit.” — Will Durant Citations1.    Wilding, J. P. H., et al. (2021). Once-Weekly Semaglutide in Adults with Overweight or Obesity. New England Journal of Medicine, 384, 989–1002.2.    Rubino, D., et al. (2021). Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance. Diabetes, Obesity and Metabolism.3.    SELECT Trial Investigators (2023). Semaglutide and Cardiovascular Outcomes in Obesity. New England Journal of Medicine.4.    Drucker, D. J. (2018). Mechanisms of Action and Therapeutic Application of GLP-1. Cell Metabolism.5.    Baggio, L. L., & Drucker, D. J. (2007). Biology of Incretins. Gastroenterology.Let's go, let's get it done.Get more information at: http://projectweightloss.org

Does it fee like food gets stuck when you swallow? Or like swallowing takes more effort than it should?  These symptoms are often dismissed—but they may be signs of Eosinophilic Esophagitis (EoE), a condition that frequently goes undiagnosed for years. In this episode of Gastro Girl, Jacqueline Gaulin sits down with Dr. Neil D. Parikh to break down what these symptoms really mean—and when it's time to take action.  In this episode: Why food may feel like it's getting stuck The difference between reflux and something more Early warning signs many people overlook When swallowing problems need medical evaluation How EoE is diagnosed and why timing matters If you've ever adjusted how you eat, avoided certain foods, or felt like swallowing just isn't right—this episode will help you connect the dots. Produced by Gastro Girl, a trusted digestive health education platform and official patient education partner of the American College of Gastroenterology. This educational initiative was developed with support from Takeda.  

Long COVID isn't one single diagnosis—it's a spectrum of post-viral patterns that can affect energy, cognition, immunity, circulation, and inflammation. In this episode, Dr. Greg Jones is joined by Dr. Robin Rose, a double board-certified physician (Internal Medicine + Gastroenterology) and a leading authority on the gut–brain–immune axis, to unpack what she's seeing clinically in patients with persistent post-COVID symptoms.Dr. Rose explains how Long COVID can present as fatigue, brain fog, immune dysregulation, clotting changes, and autoimmune-like patterns—and why symptoms can vary dramatically from person to person. She shares early lab trends she noticed during the pandemic, including shifts in white blood cell counts, abnormal iron storage markers, elevated D-dimer, and increased inflammatory signals.The conversation explores mechanisms being investigated in Long COVID, including how spike-related pathways may interact with cells and contribute to ongoing inflammation in some individuals. They also discuss microclots and circulation issues, gut-derived “toxin-like” peptides, advanced testing approaches, and why some protocols focus on binding strategies rather than aggressive breakdown.If you're trying to understand the lab patterns, symptom clusters, and root-cause frameworks being used in complex Long COVID cases, this episode provides a clinically grounded, mechanism-focused overview.

Most people think you need to poo every day to be healthy. You don't. In this episode, we explain how to tell if your poo is normal, the warning signs you shouldn't ignore, and the gut mistake you may be making on the toilet every day.  Dr Trisha Pasricha, a leading Harvard gastroenterologist, a columnist for the Washington Post and author of the book You've Been Pooping All Wrong, explains how your poo, gut health, and disease risk are linked, and when you should see a doctor. Dr Pasricha guides us through why frequency, colour, and consistency all matter, and why there is no single “normal.” You'll learn how to spot changes that could signal disease, including early warning signs linked to cancer and long-term brain health. You'll hear simple advice you can use straight away. This includes how to recognise your normal pattern, what changes to look out for, and how to avoid the common toilet habit that may affect your gut. Are you looking at your poo every day? And, if not, what might you notice if you did?

Dr. David Clarke, president of the Psychophysiologic Disorders Association, details the link between stress and chronic pain and the scope of brain-generated symptoms. Clarke says many patients have symptoms not explained by disease or injury, estimating about 20% of U.S. adults (about 50 million) live with chronic pain, with costs estimated at $650 billion, and notes clinicians are often not trained to evaluate psychosocial stressors. He describes clues that pain is brain-generated (e.g., multiple long-lasting or shifting symptoms, lack of objective nerve damage) and a broad symptom spectrum from migraines and IBS to pelvic pain and rashes. Clarke discusses adverse childhood experiences, triggers, personality traits, and repressed emotions, cites randomized trials showing “pain relief psychology” can reduce pain and change MRI findings, and shares resources including a clinician directory, self-assessment quiz, and the Curable app. 

Dr. Hoffman continues his conversation with Dr. David Clarke, president of the Psychophysiologic Disorders Association.

Send us Fan MailA lot of IBD news sounds like it should change your care tomorrow and then… nothing changes at your next appointment. We wanted to close that gap, so we invited back Dr. Victor Chedid and Dr. Iris Wang from Mayo Clinic in Rochester, MN for a Research Rroundup that's honest about what's exciting, what's early, and what still has major caveats for real people living with Crohn's disease and ulcerative colitis.We dig into emerging data on GLP-1 agonists like semaglutide and tirzepatide and why several retrospective studies are turning heads with signals for fewer hospitalizations and less steroid use in IBD patients. We also get specific about the “who should not use this” question, including risks for people who are underweight or have disordered eating concerns, and why multidisciplinary support with an IBD dietitian can matter. Robin also raises a practical angle many patients care about: whether GLP-1 medications could help slow gut transit for high ostomy output or pouch output, and what makes insurance approval so challenging.From there, we talk breakthroughs that could reshape the long game of Crohn's care: fibrostenotic Crohn's disease and strictures. An antifibrotic drug targeting intestinal fibroblasts is showing early promise, and we walk through what a phase 2 trial result really means, plus why it can still take years before a therapy becomes available in clinic. We also explore the surprising two-way relationship between sex hormones and the gut microbiome, what that could imply for symptom patterns, and why microbiome testing and “fix your gut” products often outrun the evidence.We end with what makes us hopeful over the next five years: better biomarkers, precision medicine, and AI in gastroenterology, paired with a clear warning about bias and why ChatGPT-style tools can confidently generate misinformation. If you found this helpful, subscribe, leave a review, and share the episode with someone who needs a clear-eyed update on IBD research.Links: Information from Mt. Sinai about GLP-1 Medications and IBDPreventing Fibrosis in IBD: Update on immune pathways and clinical strategiesLet's get social!!Follow us on Instagram!Follow us on Facebook!Follow us on Twitter!

This month, Health Is the Key does double duty as we spotlight National Stress Awareness Month and IBS Awareness Month. If you're wondering what stress has to do with irritable bowel syndrome and other digestive disorders, you'll be glad you tuned in. We are lucky to be joined by Dr. Preeti Mehta, a gastroenterologist and founder of the private practice Digestive Disease Care. Dr. Mehta explains the effect the brain has on the digestive system and vice-versa. She also shares practical lifestyle habits that can support long-term gut health.    The Takeaway  We want to hear from you! Please complete our survey: 1199SEIUBenefits.org/member-feedback. Drop us a line at our social media channels: Facebook // Instagram // YouTube. Find out where your health stands by making an appointment with your primary care physician. Don't have one? Find one at our Provider Directory: www.1199SEIUBenefits.org/find-a-provider.  Visit the Healthy Living Resource Center for wellness tips, information and resources; www.1199SEIUBenefits.org/healthyliving. Get to know your numbers at www.1199SEIUBenefits.org/healthyhearts.  Need support managing chronic conditions such as type 2 diabetes, hypertension or overweight? Learn about our partnerships: visit www.1199SEIUBenefits.org/the-choice-is-yours/ Browse healthy recipes and meal-prep tips at www.1199SEIUBenefits.org/food-as-medicine.  Get inspired by fellow members through our Members' Voices series: www.1199SEIUBenefits.org/healthyliving/membervoices.  Stop by our Benefits Channel to join webinars on building healthy meals, managing stress and more: www.1199SEIUBenefits.org/videos. Visit our  YouTube channel to view a wide collection of healthy living videos: www.youtube.com/@1199SEIUBenefitFunds/playlists. Sample our wellness classes to exercise body and mind: www.1199SEIUBenefits.org/wellnessevents.   Guest Bio  Preeti Mehta, MD, is a board-certified gastroenterologist and hepatologist with over 25 years of experience in digestive health care. She serves as Vice President of Digestive Disease Care, a multi-physician gastroenterology practice, and oversees two large Ambulatory Surgical Centers serving patients across Long Island and Queens.  Dr. Mehta earned her Doctor of Medicine degree from the Icahn School of Medicine at Mount Sinai and completed her internship and residency in Internal Medicine at North Shore University Hospital in Manhasset, New York. She went on to complete a Research Fellowship in Hepatology at NewYork-Presbyterian Hospital, in affiliation with Weill Medical College of Cornell University and Rockefeller University. She also completed a Clinical Fellowship in Gastroenterology and Hepatology and an Advanced Endoscopy Fellowship in Endoscopic Ultrasound at the State University of New York. She is a member of the American College of Gastroenterology, the American Society for Gastrointestinal Endoscopy and the American Association for the Study of Liver Diseases. 

Dr. Sergio Quijano is a board-certified gastroenterologist at Hamilton Physician Group - Gastroenterology in Dalton, GA. Dr. Quijano attended medical school and completed his residency training at the New York University School of Medicine. He also completed his fellowship in gastroenterology at the SUNY Health Science Center at Brooklyn.Dr. Quijano treats patients with GI conditions, including GERD, abdominal pain, peptic ulcer disease, inflammatory bowel disease, liver conditions including fatty liver, hepatitis B, C, and functional GI conditions like gastroparesis and irritable bowel syndrome. He also performs general GI procedures such as upper endoscopies, colonoscopies, flexible sigmoidoscopies, video capsule endoscopies, and manometries. To make an appointment at Hamilton Physician Group – Gastroenterology, call 706-272-4127.

Dr. Sergio Quijano is a board-certified gastroenterologist at Hamilton Physician Group - Gastroenterology in Dalton, GA. Dr. Quijano attended medical school and completed his residency training at the New York University School of Medicine. He also completed his fellowship in gastroenterology at the SUNY Health Science Center at Brooklyn.Dr. Quijano treats patients with GI conditions, including GERD, abdominal pain, peptic ulcer disease, inflammatory bowel disease, liver conditions including fatty liver, hepatitis B, C, and functional GI conditions like gastroparesis and irritable bowel syndrome. He also performs general GI procedures such as upper endoscopies, colonoscopies, flexible sigmoidoscopies, video capsule endoscopies, and manometries. To make an appointment at Hamilton Physician Group – Gastroenterology, call 706-272-4127.

Dr. Sergio Quijano is a board-certified gastroenterologist at Hamilton Physician Group - Gastroenterology in Dalton, GA. Dr. Quijano attended medical school and completed his residency training at the New York University School of Medicine. He also completed his fellowship in gastroenterology at the SUNY Health Science Center at Brooklyn.Dr. Quijano treats patients with GI conditions, including GERD, abdominal pain, peptic ulcer disease, inflammatory bowel disease, liver conditions including fatty liver, hepatitis B, C, and functional GI conditions like gastroparesis and irritable bowel syndrome. He also performs general GI procedures such as upper endoscopies, colonoscopies, flexible sigmoidoscopies, video capsule endoscopies, and manometries. To make an appointment at Hamilton Physician Group – Gastroenterology, call 706-272-4127.

In this new episode, Spill with Me Jenny D talks with Dr. Bridger Clarke, chief of Gastroenterology at St. Clair Health, about Colorectal Cancer Prevention, screening guidelines, and what to expect during a colonoscopy. Also, we discussed who should be screened (starting at age 45 for average risk), common risk factors, the importance of early detection and prevention through polyp removal, prep and recovery, and a tour of the endoscopy suite to demystify the procedure. I want to give a heartfelt thank you St. Clair Health for sponsoring this episode and for helping me bring meaningful health conversations to our community.  To learn more about colorectal cancer screening or to schedule a colonoscopy at St. Clair Health call 412-942-6700 or visit stclair.org All episodes are available on all the major Audio Platforms as well as Jenny D's YouTube page. Make sure to Subscribe and Follow. http://www.youtube.com/@Spillwithmejennyd If you would like to be a guest or sponsor on Spill with Me Jenny D. Show please fill out the disclaimer at https://www.spillwithmejennyd.com/tell-your-story or email spillwithmejennyd@gmail.com Thank you to our Community Partners! Note: "The views and conversations in this podcast are intended solely for informational and educational purposes. They do not constitute professional advice, and listeners are encouraged to seek their own guidance for any specific concerns."   "Music Credit: Theme song, written and performed by Mark Ferrari"    markferrarimusic.com  

In this new episode, Spill with Me Jenny D talks with Dr. Bridger Clarke, chief of Gastroenterology at St. Clair Health, about Colorectal Cancer Prevention, screening guidelines, and what to expect during a colonoscopy. Also, we discussed who should be screened (starting at age 45 for average risk), common risk factors, the importance of early detection and prevention through polyp removal, prep and recovery, and a tour of the endoscopy suite to demystify the procedure. I want to give a heartfelt thank you St. Clair Health for sponsoring this episode and for helping me bring meaningful health conversations to our community.  To learn more about colorectal cancer screening or to schedule a colonoscopy at St. Clair Health call 412-942-6700 or visit stclair.org All episodes are available on all the major Audio Platforms as well as Jenny D's YouTube page. Make sure to Subscribe and Follow. http://www.youtube.com/@Spillwithmejennyd If you would like to be a guest or sponsor on Spill with Me Jenny D. Show please fill out the disclaimer at https://www.spillwithmejennyd.com/tell-your-story or email spillwithmejennyd@gmail.com Thank you to our Community Partners! Note: "The views and conversations in this podcast are intended solely for informational and educational purposes. They do not constitute professional advice, and listeners are encouraged to seek their own guidance for any specific concerns." "Music Credit: Theme song, written and performed by Mark Ferrari"    markferrarimusic.com

Send us Fan MailWhen it comes to colonoscopies and colon cancer, there are a lot of myths out there about the prep, the procedure, and who should get a colonoscopy. Returning to the podcast today is Dr. Douglas Purdy, gastroenterologist with St. Luke's Gastroenterology, to discuss colon cancer screening, treatment and more. If you are 45 years or older, talk to your primary care provider today about scheduling your screening colonoscopy with St. Luke's Gastroenterology, or fill out this form to request a colonoscopy >> https://uph.link/Gastroenterology-Screening-Form If you've been diagnosed with colon cancer, or any type of cancer, the Nassif Community Cancer Center is here for you. To learn more about its extensive offering of support services, call (319) 558-4876 or visit communitycancercenter.org.If you have a topic you'd like Dr. Arnold to discuss with a guest on the podcast, shoot us an email at stlukescr@unitypoint.org.

Providing primary health care in a war zone presents some extraordinary challenges. This presentation delves into the complex world of healthcare delivery amid conflict and chaos.

Identification of pancreatic cystic lesions has become increasingly common due to improved resolution and increased utilization of cross-sectional imaging. However, there are many types of pancreatic cysts, each with varying degrees of malignant potential. In this episode from the HPB team at Behind the Knife, listen in as we discuss the clinical presentation, diagnostic work-up, and management strategies for various pancreatic cysts: Pseudocysts, Serous Cystadenomas, Mucinous Cystic Neoplasms, and IPMNs, amongst others. HostsAnish J. Jain MD (@anishjayjain) is a current PGY4 General Surgery resident at Stanford University and a former T32 Research Fellow at the University of Texas MD Anderson Cancer Center.Jon M. Harrison MD is a Hepatobiliary & Pancreatic (HPB) surgeon at the Massachusetts General Hospital in Boston, MA and a former HPB Surgery fellow at Stanford University. Learning Objectives·      Develop an understanding of the clinical presentation, diagnostic work-up, and treatment of benign pancreatic cysts·      Develop an understanding of the clinical presentation, diagnostic work-up, and treatment of pre-malignant pancreatic cysts·      Develop an understanding of when surveillance is appropriate for management of pancreatic cysts, and the criteria involved in making that determination·      Develop an understanding of the prognostic utility of PancSeq for IPMNsReferences: Paniccia A, Polanco PM, Boone BA, et al. Prospective, Multi-Institutional, Real-Time Next-Generation Sequencing of Pancreatic Cyst Fluid Reveals Diverse Genomic Alterations That Improve the Clinical Management of Pancreatic Cysts. Gastroenterology. 2023 Jan;164(1):117-133.e7.PubMed Link: https://pubmed.ncbi.nlm.nih.gov/36209796/ Ohtsuka T, Fernandez-Del Castillo C, Furukawa T, et al. International evidence-based Kyoto guidelines for the management of intraductal papillary mucinous neoplasm of the pancreas. Pancreatology. 2024 Mar;24(2):255-270.PubMed Link: https://pubmed.ncbi.nlm.nih.gov/38182527/ Zelga P, Hernandez-Barco YG, Qadan M, et al. Number of Worrisome Features and Risk of Malignancy in Intraductal Papillary Mucinous Neoplasm. J Am Coll Surg. 2022 Jun 1;234(6):1021-1030.PubMed Link: https://pubmed.ncbi.nlm.nih.gov/35703792/ Ciprani D, Weniger M, Qadan M, et al. Risk of malignancy in small pancreatic cysts decreases over time. Pancreatology. 2020 Sep;20(6):1213-1217.PubMed Link: https://pubmed.ncbi.nlm.nih.gov/32819844/ ***Fellowship Application Link: https://forms.gle/QSUrR2GWHDZ1MmWC6Sponsor Disclaimer: Visit goremedical.com/btkpod to learn more about GORE® SYNECOR Biomaterial, including supporting references and disclaimers for the presented content.Refer to Instructions for Use at eifu.goremedical.com for a complete description of all applicable indications, warnings, precautions and contraindications for the markets where this product is available. Rx only Please visit https://behindtheknife.org to access other high-yield surgical education podcasts, videos and more.  If you liked this episode, check out our recent episodes here: https://behindtheknife.org/listenBehind the Knife Premium:General Surgery Oral Board Review Course: https://behindtheknife.org/premium/general-surgery-oral-board-reviewTrauma Surgery Video Atlas: https://behindtheknife.org/premium/trauma-surgery-video-atlasDominate Surgery: A High-Yield Guide to Your Surgery Clerkship: https://behindtheknife.org/premium/dominate-surgery-a-high-yield-guide-to-your-surgery-clerkshipDominate Surgery for APPs: A High-Yield Guide to Your Surgery Rotation: https://behindtheknife.org/premium/dominate-surgery-for-apps-a-high-yield-guide-to-your-surgery-rotationVascular Surgery Oral Board Review Course: https://behindtheknife.org/premium/vascular-surgery-oral-board-audio-reviewColorectal Surgery Oral Board Review Course: https://behindtheknife.org/premium/colorectal-surgery-oral-board-audio-reviewSurgical Oncology Oral Board Review Course: https://behindtheknife.org/premium/surgical-oncology-oral-board-audio-reviewCardiothoracic Oral Board Review Course: https://behindtheknife.org/premium/cardiothoracic-surgery-oral-board-audio-reviewDownload our App:Apple App Store: https://apps.apple.com/us/app/behind-the-knife/id1672420049Android/Google Play: https://play.google.com/store/apps/details?id=com.btk.app&hl=en_US

In this episode, we break down a major factor in treating SIBO and preventing recurrence: biofilm disruption. You'll learn how to identify the telltale signs of biofilms, the steps to our proven treatment protocol, and discover the dietary and supplement strategies that support lasting gut recovery. Our approach is backed by our recently published study, Biofilm Disruption Enhances Antimicrobial Therapy for Small Intestinal Bacterial Overgrowth and Intestinal Methanogen Overgrowth. Read the full findings here:https://pubmed.ncbi.nlm.nih.gov/41394228/.    If you've struggled with recurring SIBO and felt like nothing works, this episode will guide you to effective solutions.  

If you are tired of treating symptoms without real answers, this conversation challenges how you see modern medicine. You are invited to look beyond prescriptions and quick fixes and start asking why your body is reacting in the first place. Stress, lifestyle, and inflammation often sit at the center of gut issues like IBS, reflux, and chronic discomfort. You will hear why fiber, sleep, movement, and community matter more than most people realize. Rising gut disorders and colon cancer in younger adults make prevention and early awareness critical. Instead of labeling yourself by a diagnosis, you are encouraged to see symptoms as signals your body is asking for support. The focus turns to balance. You do not have to reject traditional care, but you can pair it with meditation, exercise, and simple nutrition habits that support long term digestive health. When you shift from fear to understanding, healing becomes more practical and personal.   In this Episode, You'll Learn: Differences in Healthcare and Root Causes Connection Between Stress and Gut Issues Balancing Medical and Non-Medical Treatments Probiotics and Overall Health Increasing Gut Issues and Cancer in Younger Individuals Colon Cancer and Symptoms Breaking Bad News to Patients Approaching Health with a Different Perspective Personal Health Practices Simplifying Healthy Eating   About Dr. Sameer Islam: Dr. Sameer Islam is a West Texas native, growing up in Odessa, TX. He completed his undergraduate studies at the University of Texas in Austin, graduating with honors. Dr. Islam completed both his medical degree (MD) and master's of Business association (MBA) at Texas Tech University Health Sciences Center and Texas Tech Rawls School of Business, respectively. After completing his internal medicine training at Texas Tech University, he completed his fellowship in Gastroenterology at the Mayo Clinic in Arizona. For his entire career, he's balanced a love of working with patients and an obsession with cutting-edge scientific developments that are changing the way we see digestive health, and medicine as a whole. As a functional gastroenterologist, he can provide patients with more treatment options than those offered by traditional Western Medicine.   Connect with Anna: Email: annamarie@happywholeyou.com / info@HappyWholeYou.com Website: www.happywholeyou.com / https://linktr.ee/happywholeyou Personal Website: www.DrAnnaMarie.com Instagram: @happywholeyou Personal Instagram: @Dr.Anna.Marie Facebook: Happy Whole You LinkedIn: Anna Marie Frank Venmo: @happywholeyou

Sid is joined by Dr. George Pavlou and Steven Puchik from Gastroenterology Associates of New Jersey to talk about colon cancer screening and Sid's own recent colonoscopy experience. Dr. Pavlou explains how the procedure works, why screening now begins at age 45, and why colon cancer is one of the most preventable cancers when caught early. Sid shares his experience with the process and encourages listeners not to delay getting screened, emphasizing the importance of early detection and regular checkups. Learn more about your ad choices. Visit megaphone.fm/adchoices