POPULARITY
This week we go back in time 2 years to review a recent paper from 2023 about outcomes of cardiac transplantation in the adult congenital heart patient (ACHD). Little has been written on this topic until this very robust and large scale report. How do single ventricle ACHD patients fair at transplant and how do they compare to non-ACHD heart transplant recipients? Why might 1 and 3 year outcomes not be a 'fair' method of assessing outcomes in this very high risk patient group? How do HLHS patient outcomes compare with other single ventricles? Are there better ways to measure risk in this patient group and how might the data in this work inform risk stratification and management of failing Fontan patients in whom transplantation is being considered? These are amongst the questions posed this week to the week's expert, Dr Daphne Hsu who is Professor of Pediatrics at the Albert Einstein College of Medicine at The Children's Hospital at Montefiore.https://doi.org/10.1016/j.jacc.2023.06.037For those interested in learning more about Dr. Hsu, take a listen to episode #166 from June, 2021:https://www.spreaker.com/episode/pediheart-podcast-166-a-conversation-with-professor-daphne-hsu--45144274
In this episode, I interview Dr. Shana Burstein, a second-year pediatric hematology-oncology fellow at Children's Healthcare of Atlanta. She received her MD from Albert Einstein College of Medicine in 2021, followed by a residency in Pediatrics at the Children's Hospital at Montefiore. Her current research interest is identifying novel genomic variants associated with pediatric cancer predisposition syndromes. During this conversation, Dr. Burstein shares the challenges and life lessons she learned along the way to becoming a physician. Further, she tells us about the incredible research she has performed from her work with calcium ion channels at Memorial Sloan Kettering Cancer Center to the computational biology work she is spearheading at Emory University. Lastly, we close the interview with Dr. Burstein sharing valuable advice for those aspiring to have a successful and healthy career in medicine.
Co-hosts Ryan Piansky, a graduate student and patient advocate living with eosinophilic esophagitis (EoE) and eosinophilic asthma, and Holly Knotowicz, a speech-language pathologist living with EoE who serves on APFED's Health Sciences Advisory Council, interview Fei Li Kuang, MD, PhD, an allergist and immunologist, at Northwestern Medicine, about receiving two APFED HOPE on the Horizon Grants. Disclaimer: The information provided in this podcast is designed to support, not replace, the relationship between listeners and their healthcare providers. Opinions, information, and recommendations shared in this podcast are not a substitute for medical advice. Decisions related to medical care should be made with your healthcare provider. Opinions and views of guests and co-hosts are their own. Key Takeaways: [:50] Co-host Ryan Piansky introduces this episode, brought to you thanks to the support of Education Partners GSK, Sanofi, Regeneron, and Takeda. Ryan introduces co-host Holly Knotowicz. [1:14] Holly introduces today's topic, two APFED HOPE on the Horizon Pilot Grant Projects and today's guest, Fei Li Kuang, MD, PhD, an Assistant Professor in the Division of Allergy and Immunology at Northwestern University Feinberg School of Medicine in Chicago, Illinois. [1:42] Dr. Kuang is a physician-scientist who takes care of patients with eosinophilic disorders and also performs laboratory research on these disorders in her lab, often using patient samples. Holly thanks Dr. Kuang for joining us. [2:05] As a child, Dr. Kuang always wanted to be a scientist. She is so grateful to live out her childhood dream, and it's because of the amazing people who have supported her, most importantly, her parents. [2:29] In graduate school, Dr. Kuang studied B cells. When she went on to do an allergy fellowship, she thought she would study B cells and care for patients with B cell problems. Instead, she fell in love with allergy and eosinophilic disorders. [2:50] Dr. Kuang is here, in part, because of the different mentors she has had, and in large part, because of the patients she has met along the way. [3:20] Dr. Kuang had the opportunity to work with Amy Klion at the NIH in a clinical trial to treat patients with a drug that gets rid of eosinophils. She says it was a dream come true after her training. [4:02] She says she learned so much about eosinophils, their unusual biology, and the mystery behind what they are here for. She got hooked. [4:15] Dr. Kuang thinks the patients you meet in a clinical trial in a special place like NIH occupy a space in your heart that makes you want to keep working on the subject area. [4:34] Patients in a clinical trial have given up a bunch of their time to travel to Bethesda, Maryland. For the trial Dr. Kuang participated in as a Fellow, it was a good year of their time to come out and do it. [4:47] Dr. Kuang felt there were so many interesting questions, from an intellectual point of view, but there was also a real need from patients with chronic conditions. It was a beautiful opportunity to marry scientists with physicians in training. [5:36] Dr. Kuang shares some knowledge about eosinophils. They are white blood cells that are in all of us. They have little pink packages or granules that "jumped out" in the light microscope almost 200 years ago, when we first identified them. [6:00] Dr. Kuang says that animals, dating back to reptiles, and different species of dolphins, all have eosinophils. A veterinary scientist, Dr. Nicole Stacy of the University of Florida, has taken photos of eosinophils from all these different species. [6:21] They've been around for a long time. What are they good for? What we know is that they are associated with disease conditions, such as asthma and others, including leukemia. Those were the classic first studies of eosinophils. [6:42] Now, we have a different mindset about eosinophils from work by the late James Lee at Mayo Clinic, Arizona. [6:58] Dr. Kuang credits Dr. Lee with suggesting that eosinophils not just cause us problems but also help treat parasitic infections, maintain tissue homeostasis, help wound healing, and tissue repair. That's a new area we are beginning to appreciate. [7:41] Dr. Kuang says we need to be open-minded that in some circumstances, eosinophils may be helpful or innocent. Now we have tools to start to understand some of that. We need to collect information from patients being treated with medicines. [8:10] Ryan tells of being diagnosed as a kid. Doctors explained to him that eosinophils fight parasites, but in some people, they get confused and attack the esophagus. That's EoE. That was easy to understand, but he knew that the researchers knew more. [8:53] Ryan is grateful to the patient population around eosinophilic esophagitis, and is proud of APFED's support of patients and caregivers with HOPE Grants. APFED has the HOPE on the Horizon Research Program, entirely funded by community donations. [9:13] To date, APFED has directed more than $2 million toward eosinophilic disease research initiatives through various grant programs. As a patient advocacy organization, APFED works with fantastic researchers who submit innovative research ideas. [9:32] These research ideas go through an extensive and competitive peer-review process, supported by researchers and clinicians in the APFED community. [9:42] Today, we're going to discuss two different projects supported by HOPE Pilot Grants with Dr. Kuang. [10:00] Dr. Kuang thinks there are two ways these grant programs are important to patients. One is advancing research by nurturing seedling investigators. Dr. Kuang got her first grant when she was a Fellow. It was an incredible opportunity. [10:25] These grant programs also nurture seedling ideas that don't have enough evidence yet to garner the larger NIH grants, and so forth. There are other sources for grants: pharmaceutical companies. The grant programs are for seeds. [10:49] Patients need to know that there are new things that are given some chance of being tested out. Research takes some time, and the FDA process of getting a drug approved is long. [11:04] For the newly diagnosed patient, it can feel overwhelming. It feels like there's a loss of control. Sometimes, participating in something like APFED, being part of a community, gives back a sense of control that is lost when you're handed a diagnosis. [11:45] For patients who have had it for a long time, when they participate in research and become engaged in organizations like APFED, they know they may not directly benefit today, they may benefit later, but they hope future patients will benefit. [12:21] That gives them a sense of control and hope that things will be better for the next generation. We all want that, especially in medicine, in something that we don't have a very deep understanding of. [12:58] Dr. Kuang received two HOPE Pilot Grants, one in 2018 and one in 2022. The first grant was awarded when she was a Fellow at the NIH. [13:05] That first grant explored some effects of eosinophilic depletion of pathogenic lymphocytes in hypereosinophilic syndrome and overlaps with EGIDs. Ryan asks for a broad overview of that research. [13:25] When Dr. Kuang was a Fellow at the NIH, they were doing a Phase 2 clinical trial, looking at "blowing up" eosinophils in patients who have a lot of them, hypereosinophilic syndrome patients. [13:39] They included patients who had eosinophilic GI disease, often beyond the esophagus. They may have esophageal involvement, but sometimes their stomach is impacted, sometimes their large bowel is impacted, with related symptoms. [13:57] What Dr. Kuang and the team noticed in the trial was that just within that little group of patients, there were people who did well, and people who did much better than before, but would have recurrent symptoms, and with no eosinophils in their GI tissues. [14:16] The researchers wanted to know what was causing these problems for the patient. If you take eosinophils away, what other factors will impact the immune system of the patient, semi-long-term? [14:32] Their focus was on these groups of patients who had different responses. They looked at the white blood cells that had been previously described as being the responsible, "bad" T cells that lead to eosinophils in the gut. [14:49] They found that the patients who had recurrent flares of the disease had more of the bad T cells, and the patients who responded well and never complained again about symptoms did not. [15:03] That allowed researchers to identify that there were subsets of patients with the disease that they were calling the same thing. [15:18] Dr. Kuang says that work also led them to find that those cells were being reported in patients who had food allergies for which they needed an epinephrine auto-injector. [15:27] The researchers were curious whether that was just a food allergy issue, or only applied if you had food allergies and eosinophilic GI disease. That HOPE project allowed them to do a pilot study to look at food allergy patients, too. They did, and published it. [15:45] They published that in patients who have a food allergy and have these T cells, the insides of those cells make different messages for the immune system than the ones that the researchers had previously described. [16:01] In looking for why there were differences in those responses, they accidentally found that there were differences inside these cells in a completely different disease, which also had these T cells. [16:21] Dr. Kuang says that the finding was kind of a surprise. If they had found anything in the eosinophilic GI disease patients, that would have been good. They also looked at the epithelial cells and the structure of the GI lining. [16:42] Even though there were no eosinophils in the GI lining in the patients who had been treated with a biologic that depleted eosinophils, their GI lining still looked like the GI lining of patients who had eosinophilic GI disease. [16:55] Dr. Kuang asked what was creating those spots. Our gut lining sheds, so there should have been an opportunity for the GI lining to turn over and look new. Something was there, making signals to create these spots. They did a different publication on that. [17:21] The data from the HOPE Pilot study allowed Dr. Kuang to apply for larger grants. It allowed her to propose to the company that made this drug, when they did the Phase 3 trial, to insert into that special study the study on eosinophilic GI disease. [17:48] Do patients with eosinophilic GI disease do better or worse on this drug, and how do the T cells look in that trial? That HOPE Grant gave Dr. Kuang the data to ask the drug company to give her money to study it in an international cohort of patients. [18:17] There were only 20 patients in that first NIH trial, who gave a year of their life, coming to NIH all the time. They continued to be in the study until the drug was approved for asthma. [18:28] Dr. Kuang says the main reason the company did the Phase 3 trial, which is expensive, and the market share is not huge because it's a rare disease, is that two of the patients went to bat for this disease population. [18:47] The two patients went and showed the business people what they looked like before, what the drug had done for them, and how their lives had changed. It wasn't the doctors or the great paper from the trial, but the patients who convinced the company. [19:01] Dr. Kuang says she was so floored by that and moved by what they did for the community. She is grateful. [19:24] Since the Phase 3 trial, Dr. Kuang and the other researchers realized they had not fully studied the eosinophils. They had studied them in part. They found differences in response. This inspired the second APFED HOPE Pilot Grant. [21:19] In 2022, Dr. Kuang received a two-year APFED HOPE Pilot Grant to examine how blood eosinophils in Eosinophilic Gastrointestinal Diseases differ from those of other eosinophilic diseases and how T cells in EGIDs differ from those in food allergies. [21:49] Dr. Kuang says normally, the biggest place of residence for eosinophils is the GI tract. That's where they are normally seen in people who do not have eosinophilic disorders. [21:59] People who have eosinophilic disorders that attack other parts of the body, asthma, and rarely, the heart. Dr. Kuang was curious to know why one person and not the other? [22:15] Patients who have eosinophilic GI disease often ask, How do you know this high level in the blood is not going to attack my heart or my lungs in the future? Dr. Kuang does not know. [22:29] Dr. Kuang says, looking at the cohort at the NIH, that for many patients who have both GI organ involvement and some other space, when they first went to see a provider, their first complaint was a GI condition. [22:54] If the doctor had only diagnosed a GI condition, nothing else, that would have been wrong. Those patients may not have been monitored as well. A third of the patients originally presented like that. [23:11] What that meant was that we should be paying attention to patients who have GI disease who have lots of eosinophils in their blood. Moving forward, if there are new complaints, we need to investigate. We can't forget they have that. [23:27] Dr. Kuang asks, Wouldn't it be great if we had a better tool than needing to wait? Wouldn't it be great if we had a biomarker that said the eosinophils have switched their target location and are going somewhere else? [23:41] One way to do that is to take different groups of eosinophils and look for differences between those that never target the GI tract and those that do. In patients who have EoE, the eosinophils only target or cause problems in the esophagus. [23:58] Are their eosinophils any different than those of a healthy person, with none of these conditions? That was the goal of that study. [24:10] T cells are another type of white blood cell. They contain a memory of foreign things they have encountered, which allows them to glom onto flu, COVID, peanuts, pollen, that kind of thing. They remember. [24:32] Dr. Kuang says they learned that T cells, at least in the mouse model, are required in the development of eosinophilic esophagitis. The mice in the old study, where mice were forced to develop EoE, did not get EoE if you removed their T cells. [24:50] In the first APFED HOPE grant study, Dr. Kuang found T cells in the blood and tissue of both EGIDs and food allergy patients, but the insides of the T cells were different. The food allergy patients were children recruited by a pediatric allergist. [25:19] In the second APFED HOPE grant study, at Northwestern, Dr. Kuang recruited her adult food allergy patients. That was a way to validate what they found in the first study and move further to better characterize those T cells in the two different diseases. [25:47] Dr. Kuang says we're at a point where we've recruited a lot of people. She says it's amazing what people are willing to do. It's very humbling. [26:06] Dr. Kuang's team in the lab is really great, too. To accommodate patients, they would see them after work, if that's what they had to do to isolate eosinophils. So they did that, and now they are in the process of analyzing that data. It's really exciting. [26:28] What's exciting is that they are seeing results that show that eosinophilic GI disease patients have circulating eosinophils that are different from the eosinophils of people who don't have GI involvement, and from people who have EoE. [26:46] The EoE patients have eosinophils different from those of healthy donors. Dr. Kuang says there's a lot of promise for perhaps unique signatures that could help define these conditions; maybe someday without biopsying, but that's a long time away. [27:16] Dr. Kuang says they will focus on some candidate targets and try to recreate some of that in a dish with eosinophils from healthy people. [27:26] What are the signals that lead eosinophils to do this, and can we translate that back to available drugs that target certain cytokines or other pathways, and maybe give some insight to develop drugs that target other pathways for these diseases? [28:17] Ryan thinks it's exciting that this research is narrowing in on not only the different symptoms, but also how the eosinophils are acting differently in these populations. [28:44] Dr. Kuang is super excited about this research. You could imagine that all eosinophils are the same, but you don't know until you look. When they looked, using the newest technology, they found there were differences. [29:33] Dr. Kuang says it is thought that T cells respond to triggers. We don't think eosinophils have a memory for antigens. T cells do. That's one of their definitions. When T cells react to a trigger, they give out messages through cytokines or by delivery. [30:20] Those are the messages that recruit eosinophils and other cells to come and stir up some trouble. [30:28] In the mouse model, where you don't have the T cells, and you don't get eosinophilic esophagitis in the particular way they made it happen in a mouse, that middle messenger is gone, so the eosinophils don't know where to go. [30:44] With drugs that take out eosinophils, you think that you've gotten rid of the cell that creates all the problems. It shouldn't matter what the message says because there's no cell there to cause the damage. [30:58] What Dr. Kuang learned is that, at least in certain eosinophilic GI diseases, that's not true. You erase the eosinophils from the picture, but that message is still coming. [31:10] Who's carrying out the orders? Or is that message maintaining the wall of epithelial cells in a certain way that we didn't appreciate because the eosinophils were also there? [31:24] It's important to study both, because one is the messenger and the other is one of the actors. Whether all of the actions taken by eosinophils are bad, or maybe some of them were meant to be good, we have yet to learn. [31:40] At the moment, we're using it as a marker for disease activity, and that may change in the future, as we learn more about the roles of these cells in the process. [31:50] We have drugs now that target eosinophils and drugs that target T cells. Dr. Kuang thinks it's important to study both and to study the impact of these drugs on these cells. [32:02] You could theoretically use these drugs to understand whether, if someone responds to it, what happens to these cells, and if someone doesn't respond to it, what happens to these cells, and how this disease manifests in this flavor of patients. [32:54] Dr. Kuang says, Often in science, we take a model. We think this works this way. Then, if this works this way, we expect that if we remove this, these things should happen. We did that with the first clinical trial, with NIH patients. [33:10] It didn't quite happen the way we thought, so we had to go looking for explanations. These were unusual setbacks. Sometimes you have unusual findings, like the food allergy part. [33:24] When Dr. Kuang went to Northwestern, she saw different cohorts of patients than she saw at NIH. She saw people who were seen every day, which is a different spectrum than those who are selected to be enrolled in a study protocol at the NIH. [33:42] That broadened her viewpoint. It's maybe not all food-triggered. They were seeing adults who'd never had food allergies or asthma their whole life, and they had eosinophilic esophagitis suddenly as a 50-year-old. There's a significant group of them. [34:10] What Dr. Kuang learned and tries to be open-minded about is that where you train, what sorts of patients you see, really shape your viewpoint and thinking about the disease process and the management process. [34:24] Dr. Kuang says she was so lucky to have experienced that at a quaternary care referral center like the NIH and at an academic center like Northwestern, where there are fantastic gastroenterologists who see so many of these patients. [34:56] Dr. Kuang and an Allergy Fellow knew they were going to get a wonderful data set from the NIH patients they had recruited, so they thought they had better look deeply at what had been learned before with older technology, with mice and people. [35:13] They decided to gather previous research, and that ultimately got published as an article. From that research, they learned that people did things in many different ways because there was no standard. They didn't know what the standard should be. [35:28] Different things you do to try to get eosinophils out of tissue impact how they look, in terms of transcript, gene expression, and what messages they make to define themselves as an eosinophil. [35:43] They also learned that because eosinophils are hard to work with, they die easily, and you can't freeze them and work on them the next day; you can introduce issues in there that have to be accounted for. [35:59] They learned that as an eosinophil research community, they ought to come up with some standards so that they can compare future studies with each other. Dr. Kuang says it was impossible to compare the old studies that used different premises. [36:50] Dr. Kuang says we need to be proactive in creating the datasets in a standard way so that we can compare and have a more fruitful and diverse community of data. It's hard to use the old data. [37:57] Dr. Kuang says they get fresh blood from patients, and because eosinophils are finicky, they need to be analyzed within four hours, or preserved in a way to save whatever fragile molecules are to be studied. [38:19] If you let it sit, it starts dying, so you won't have as many of them, and they start changing because they're not in the body. Dr. Kuang experimented with putting a tube of blood on the bench and checking it with the same test every two hours. It changes. [38:38] Four hours is a standard to prevent the eosinophils from dying. Patients need treatment. If a patient is hospitalized and needs treatment, Dr. Kuang's team needs to be there to get a sample before treatment is started. [39:03] The treatment impacts it, changing the situation. Much of the treatment, initially, is steroids. When you give lots of steroids, the eosinophils go away. It's no good to draw their blood then. [39:27] Dr. Kuang also gets a urine sample. The granules of the eosinophils can get into the urine. As they study people with active disease, they want to capture granule proteins in the urine as a less invasive way to monitor activity in different disease states. [40:04] The patient just needs to give Dr. Kuang either arm and a urine sample. [41:04] Dr. Kuang explains, you can count your eosinophils after four hours, but to study them, they have different flags of different colors and shapes. Those colors and shapes may mean that it's an activated eosinophil, or they may have other meanings. [41:41] Dr. Kuang focused on markers that look at whether it's going to spill its granules and some traditional markers of activation. [41:50] Everyone chooses a different marker of activation. So they decided to look at as many as they could. One marker is not sufficient. They seem to be different in different conditions. The markers are on the surface; you need to analyze them right away. [42:20] Then, Dr. Kuang breaks open the eosinophils and grabs the messenger RNA. They preserve it to do sequencing to read out the orders to see what this eosinophil is telling itself to make. RNA chops up messages. [43:00] When you open an eosinophil, a protein you find is RNA, which chops up messages, destroying parts of the cell. You want to save the message. There's a brief time to analyze the eosinophil. Dr. Kuang works to preserve and read the message. [44:04] Dr. Kuang hopes someday to run a tube of blood, look at the flags on the eosinophils, and say, "I think your eosinophilic GI disease is active," or "You have a kind of eosinophilic GI disease we need to monitor more frequently for organ damage." [44:38] If another patient doesn't have those flags, Dr. Kuang could say, "I think the chances that you're going to have involvement elsewhere are low." That can give reassurance to folks who are worried. [45:15] Dr. Kuang hopes that someday we can understand better why some people have food allergies vs. eosinophilic GI disease. They both have T cells, but the T cells have different packages inside with messages to deliver. [45:34] Every day, Dr. Kuang has to tell patients she doesn't have that answer. Someday, she hopes she can tell a patient she does have that answer. [46:35] Dr. Kuang tells about an NIH grant she's excited about and the patients she recruits after therapy, or elimination diets, to examine eosinophils and T cells, to see the impacts their treatments or diets have had on eosinophilic GI disease. [47:18] Dr. Kuang believes there will be predictors of who will respond to an elimination diet and who will respond to steroid therapy. She hopes one day to have that, rather than going through rounds of six to eight weeks followed by a scope. [47:34] If you have an elimination diet for six to eight weeks, every time you add back a food, you have to do a scope. Dr. Kuang says it would be great if you could be more precise ahead of time for therapy. [47:48] Dr. Kuang says these wonderful drugs selectively take out parts of the pathway in the immune system. They provide real-life opportunities to ask, why is this important in human biology and the human immune system? [48:15] Dr. Kuang finds the knowledge itself fascinating and useful. She hopes it informs how we choose future drugs or therapeutic avenues to get the best we can out of what we've learned, so we have more targeted ways of treating specific diseases. [48:48] Ryan is grateful for all the research happening for the eosinophilic disease community and all the patients participating in the research. He asks Dr. Kuang how a patient can participate in research. [49:12] There are lots of ways to be involved in research. Dr. Kuang says her patients come away from participating in research feeling good about having done it. [49:22] Answer a survey, if that's what you have bandwidth for. Where therapies are changing, being a part of a community is good for the community, for the future, but it's good for you, too. It's healing in ways that are not steroids or biologics. [49:58] Being part of a community is healing in ways we all need when we feel alone and bewildered. You're not alone. [50:12] There are many ways to participate: APFED, CEGIR, individual institutions, and clinical trials. They all have different amounts of involvement. It's worthwhile to participate, not only for future patients but for yourself. They're fantastic! [50:56] Dr. Kuang talks about the privilege as a physician of working with APFED and other organizations to do this work. [51:09] Holly thanks Dr. Kuang for sharing all of this research and exciting information. [51:25] Dr. Kuang is excited about what her group is doing and is hopeful. Besides showing up for this disease, we have to show up for research, in general, in this country. It's a dark time for NIH research funding. [51:55] Dr. Kuang asks the young listeners who are thinking of choosing a field to see the potential and get into it, study this, and believe that there's going to be a future with a more nurturing research environment. [52:36] Dr. Kuang would hate to lose generations of scientists. She says that once she was a little girl who was trying to be a scientist. Her parents had no connections with scientists or doctors, but she was able to get into research, and she thinks you can, too. [53:48] As a graduate student, Ryan has always been interested in trying to improve things, and he sees hope on the horizon. He's very grateful to the APFED community for supporting these research HOPE Pilot Grants. [54:17] Ryan is very grateful to Dr. Kuang for joining us today. [54:22] For our listeners who want to learn more about eosinophilic disorders, we encourage you to visit apfed.org and check out the links in the show notes. [54:28] If you're looking to find a specialist who treats eosinophilic disorders, we encourage you to use APFED's Specialist Finder at apfed.org/specialist. [54:37] If you'd like to connect with others impacted by eosinophilic diseases, please join APFED's online community on the Inspire Network at apfed.org/connections. [54:57] Dr. Kuang thanks Ryan and Holly and says she enjoyed the conversation. Holly also thanks APFED's Education Partners GSK, Sanofi, Regeneron, and Takeda for supporting this episode. Mentioned in This Episode: Fei Li Kuang, MD, PhD, Allergist and Immunologist, Northwestern Medicine Grants and publications discussed: Apfed.org/blog/apfed-announces-2018-hope-apfed-hope-pilot-grant-recipient/ Apfed.org/blog/fei-li-kuang-hope-pilot-grant-award/ Pubmed.ncbi.nlm.nih.gov/39213186/ Pubmed.ncbi.nlm.nih.gov/37487654/ APFED on YouTube, Twitter, Facebook, Pinterest, Instagram Real Talk: Eosinophilic Diseases Podcast apfed.org/specialist apfed.org/connections apfed.org/research/clinical-trials Education Partners: This episode of APFED's podcast is brought to you thanks to the support of GSK, Sanofi, Regeneron, and Takeda. Tweetables: "I think the patients that you meet in a clinical trial, especially in a special place like NIH, occupy a space in your heart — I don't mean to be all too emotional about this — that makes you want to keep working on the subject area." — Fei Li Kuang, MD, PhD "When I was a Fellow at the NIH, we were doing a Phase 2 clinical trial, looking at, for want of a better word, "blowing up" eosinophils in patients who have a lot of them, hypereosinophilic syndrome patients." — Fei Li Kuang, MD, PhD "We're at a point where we've recruited a lot of people. I've had patients drive from the northern part of Illinois … come down and give me blood. It's amazing what people want to do and are willing to do. It's very humbling, actually." — Fei Li Kuang, MD, PhD "You erase the eosinophils from the picture, but that message is still coming. Who's carrying out the orders? Or is that message maintaining the wall of epithelial cells in a certain way that we didn't appreciate because the eosinophils were also there?" — Fei Li Kuang, MD, PhD "We need to be proactive in creating the datasets in a standard way so that we can compare and have a more fruitful and diverse community of data." — Fei Li Kuang, MD, PhD "I think it's worthwhile to participate [in a clinical trial], not only for the future people but for yourself." — Fei Li Kuang, MD, PhD Guest Bio: Fei Li Kuang, MD, PhD, is currently an Assistant Professor in the Division of Allergy and Immunology at Northwestern University Feinberg School of Medicine in Chicago, IL. She is a graduate of the Albert Einstein College of Medicine Medical Scientist Training Program with both a PhD in Cell Biology/Immunology and an MD. She completed her Internal Medicine Residency at Columbia University, New York Presbyterian Hospital in New York City, she did her Fellowship in Allergy and Immunology at the National Institute of Allergy and Infectious Disease (NIAID) in Bethesda, Maryland. She is a physician-scientist who takes care of patients with eosinophilic disorders and also performs laboratory research on these disorders in her lab, often using patient samples.
Show Highlights · It’s Your Life With Dr James JC Cooley and Co-Host Dr Michael Mantell- Rational Emotive & Cognitive Behavior Coach have a sit-down conversation with Dr.Manju Chacko Dawkins – Board-Certified Dermatologist and the creator and co-founder of Thimble. · Needle Pain & Fear Are a Public-Health Crisis and We Aren’t Talking About It· Healthcare Has Normalized Pain and It’s Costing Us Trust· Introducing Thimble: The First Needle Care System· A New Standard of Care Is Possible and We’re Already Building It. Biography Dr. Manju Dawkins is a board-certified dermatologist who received her B.A. from Columbia University and her M.D. from the University of Maryland. She completed her dermatology residency — and served as Chief Resident — at the Albert Einstein College of Medicine in the Bronx, NY. She later joined the faculty at the Mount Sinai School of Medicine, where she was twice named Teacher of the Year. Dr. Dawkins has practiced dermatology in academic, private, hospital-based, and group practice settings in both New York and Los Angeles. She is also the creator and co-founder of Thimble, the first easy, safe, and comprehensive solution for reducing needle pain and stress. Thimble was awarded the Grand Prize at the 2023 American Academy of Pain Medicine Innovation Challenge and the 2024 Innovation Award by the Skin of Color Society. www.thimblehealth.com Social Media Instagram: https://www.instagram.com/thimble.health LinkedIn (Company): https://www.linkedin.com/company/thimblehealth LinkedIn (Dr. Dawkins): https://www.linkedin.com/in/manju-dawkins-md/ TikTok: https://www.tiktok.com/@thimble.healthSupport the show: http://www.cooleyfoundation.org/See omnystudio.com/listener for privacy information.
This episode brings together the science, the medicine, and the lived experience behind BRCA mutations. Emily Goldberg, JScreen's Director of Genetic Counseling Services, breaks down what these mutations are, how they're inherited, and what the actual cancer risks look like. Dr. Melissa Frey, a GYN oncologist at Cornell who works closely with high-risk families, walks us through what happens after someone tests positive — from screening to risk-reducing surgeries to the big conversations around fertility and timing. We also hear from Heather Boussi, who shares her powerful story of living with both BRCA1 and BRCA2 mutations. She talks about diagnosis, surveillance, surgeries, and how this all shaped her family-building decisions. Lastly, we look at what BRCA means for men, how that journey differs, and why PGT can still be an option. If you or someone you love is navigating this, we close with places to turn for support: JScreen, Sharsheret, I Was Supposed To Have A Baby, and Stardust (links below). It's a mix of expertise, honesty, and heart — the kind of conversation so many people wish they had heard earlier, especially when faced with such difficult decisions. Note: This episode is the 4th of a series of 5 that we are collaborating on with Jscreen in 2025. Take a look at our previous three episodes here : Episode 157: Introduction to Genetics and Infertility Episode 166: Fragile X Syndrome: A Silent Factor in Infertility Episode 185: It's Not Just Her: Male Factor Fertility and Genetics Uncovered Resources: Genetics and Personalized Cancer Prevention Program Facing Our Risk Empowered (FORCE) Jewish Fertility Foundation Stardust Foundation Sharsheret JScreen More about Emily Goldberg: Emily Goldberg serves as the Director of Genetic Counseling Services at jscreen, where she is dedicated to helping individuals understand and manage their genetic health. With dual bachelor's degrees in biology and psychology from Brandeis University and a master's degree in Human Genetics from Sarah Lawrence College, Ms. Goldberg has been a certified genetic counselor since 2011. Prior to joining jscreen, she worked at Montefiore Medical Center in the Bronx, specializing in prenatal and cancer genetics. In addition to her role at jscreen, Ms. Goldberg is committed to education, serving as an Instructor at the Albert Einstein College of Medicine and adjunct faculty at Sarah Lawrence College, where she teaches and mentors future genetic counselors. Her expertise and dedication make her a key member of the jscreen team. Connect with JScreen: - visit their website here - check out their Instagram More about Melissa Frey, MD: Dr. Melissa Frey is an Associate Professor of Obstetrics and Gynecology in the division of Gynecologic Oncology and the Director of the Genetics and Personalized Cancer Prevention Program at Weill Cornell Medicine / NewYork Presbyterian Hospital. Dr. Frey's clinical care and research focus on the management of individuals with hereditary cancer syndromes (e.g. BRCA1, BRCA2, Lynch syndrome) and strong family history of breast and gynecologic cancers. She performs gynecologic cancer risk-reducing surgeries and is the principal investigator on several large trials aimed at cancer prevention among high-risk individuals. Dr. Frey has presented her research at national and international meetings and has more than 130 publications in peer-reviewed scientific journals. Connect with Dr. Melissa Frey: - check out her Instagram - view the Genetics and Personalized Cancer Prevention Program website More about Heather Boussi : Heather grew up in Westchester, NY and now lives in Englewood, NJ with her husband and three children. Her personal experience with hereditary cancer risk and genetic testing has made her a passionate advocate for awareness, education, and empowerment in women's health. Grounded in faith and family, Heather shares her story to help others approach life's challenges with strength, perspective, and gratitude. Connect with Heather: - check out Heather's Instagram Connect with us: -Check out our Website -Follow us on Instagram and send us a message -Watch our TikToks -Follow us on Facebook -Watch us on YouTube -Connect with us on LinkedIn
Genetics professor Dr. Jan Vijg explains how DNA damage causes aging and why human lifespan may be limited to 115 years. Learn about the 100,000 DNA hits your cells take daily, breakthrough research on the DREAM gene complex that could slow mutation accumulation, and whether we can extend maximum lifespan.In this conversation, Dr. Jan Vijg, Professor and Chair of Genetics at Albert Einstein College of Medicine, explains how genome instability drives the aging process. We explore how your cells sustain 100,000 DNA lesions daily, the difference between DNA damage and somatic mutations, and why mutations accumulate exponentially with age.Dr. Vijg discusses his controversial 2016 Nature paper arguing human maximum lifespan is capped at 115 years, and why mean lifespan improvements don't translate to breaking this limit. He shares exciting new research on the DREAM gene complex - a potential master regulator that could enhance DNA repair across multiple pathways simultaneously.Key topics include: how DNA repair systems decline with age, why long-lived species have better repair mechanisms, tissue-specific mutation rates, the role of SIRT6 and NAD in DNA repair, rare genetic variants in centenarians, and whether pharmacological interventions could slow aging at the cellular level.
How far are people willing to go for glass skin and a clear face? For years, we have witnessed adventurous — and sometimes extreme — pursuits within skincare and cosmetic treatments in the quest for ageless beauty. We've heard it all: the Vampire Facial, human placenta for collagen, snail slime, and, in recent years, salmon sperm DNA. From celebrities like Jennifer Aniston to Kim Kardashian, salmon sperm facials have become the latest craze promising skin regeneration, brightening, and that coveted youthful glow. But what exactly is salmon sperm DNA therapy, and does it actually work — or is it just another viral beauty trend swimming through social media?In this episode, we are joined by Dr. Lanna Cheuck, DO, FACS. Dr. Cheuck is a board-certified urologic surgeon specializing in aesthetics and sexual health and is the CEO and Medical Director of LC Medical Aesthetics, a medical spa empire with multiple locations specializing in cosmetic surgery, injectables, sexual health.Dr. Cheuck received her DO from the NYIT College of Osteopathic Medicine, completed her Urology Residency at Brown University, and pursued a Minimally Invasive Urologic Surgery Fellowship at Albert Einstein College of Medicine. Currently, Dr. Cheuck is an Assistant Professor of Head and Neck Facial Anatomy at Montefiore Hospital, National Trainer for Galderma Aesthetics (a center of education for GAIN training), Owner and National Trainer for FACE Med-Spa Training, Co-Founder of FACE Med Store, and the Host and Co-Founder of Future of Aesthetics Global Summit (an inclusive network for virtual aesthetics). Dr. Cheuck has been featured on Forbes, Cosmopolitan, New York Post, Well+Good, RealSelf News, Global Woman Magazine, Asian Hustle Network, and NewBeauty.Follow Friends of Franz Podcast: Website, Instagram, FacebookFollow Christian Franz (Host): Instagram, YouTube
Is it true that people with bipolar disorder have different sleep needs to maintain wellness? How many hours of sleep is optimal? Dr. Holly Swartz breaks down why sleep regularity is so essential for mood stability - and what the science actually tells us.Bipolar Explained is a new #talkBD series spotlighting expert perspectives on the history, biology, and management of bipolar disorder.--Dr. Holly A. Swartz is Professor of Psychiatry at the University of Pittsburgh School of Medicine and President of the International Society of Bipolar Disorders (ISBD). She received her undergraduate degree from Harvard College, medical degree from Albert Einstein College of Medicine, and completed her psychiatric residency training at New York Hospital / Cornell University School of Medicine. Dr. Swartz's research focuses on understanding and optimizing treatments for mood disorders. She is well known for her work evaluating Interpersonal Psychotherapy (IPT) and Interpersonal and Social Rhythm Therapy (IPSRT) as treatments for depression and bipolar disorder. Her research focuses on the role of IPSRT and pharmacotherapy in the management of bipolar II depression and IPT in the management of maternal depression. She is engaged in collaborative projects to develop computational frameworks to model dyadic interpersonal behaviors in relation to psychotherapy process and outcomes and to understand neural correlates of change in chronotherapeutic behavioral interventions. Her research has been funded by the National Institute of Health, National Science Foundation, and the Brain and Behavior Research Foundation.
In this episode, Sakara founders Whitney Tingle and Danielle DuBoise sit down with world-renowned fertility expert Dr. Zaher Merhi, founder and medical director of the Rejuvenating Fertility Center. Named one of the Top 2% Scientists in the World, Dr. Merhi is pioneering a new era of women's health—one where fertility, longevity, and regenerative medicine are deeply interconnected. Together, they explore groundbreaking new frontiers in fertility—from stem cell ovarian rejuvenation and reproductive immunology to natural and low-dose IVF alternatives. Dr. Merhi challenges traditional fertility medicine, emphasizing that IVF isn't always the answer—and that many women can restore fertility and hormonal health by addressing underlying inflammation, immune imbalances, and lifestyle factors. Whether you're thinking about kids, navigating perimenopause, or simply curious about optimizing your hormonal health, this conversation offers a powerful perspective: your fertility is a reflection of your overall vitality—and supporting it means nurturing your whole body, mind, and spirit. Dr. Merhi Shares: Why inflammation is at the root of many fertility challenges How reproductive immunology helps prevent miscarriage and support healthy pregnancies The science of PRP and stem cell ovarian rejuvenation Why IVF is not the only answer The link between mental state, nourishment, and fertility How regenerative therapies like ozone and exosome treatments are advancing longevity and hormonal health Check out the video version on the Sakara Life YouTube channel here: https://youtu.be/uTjlwH7wNhM About Dr. Merhi: Dr. Merhi is the founder and the medical director of Rejuvenating Fertility Center (RFC). He is an internationally recognized fertility doctor, lecturer, editor, and grant reviewer. His training and faculty appointments included Albert Einstein College of Medicine/Montefiore Medical Center, NYU School of Medicine, and University of Vermont. He was a Professor at SUNY Downstate Health Sciences University and the Director of the Reproductive Endocrinology and Infertility (REI) Fellowship program (ACGME accredited). He is currently a Professor at Albert Einstein College of Medicine and Maimonides Medical Center in New York. He has 3 American Board certifications in OB/GYN, Reproductive Endocrinology and Infertility, and High-Complexity Laboratory Director (HCLD). Dr. Merhi is one of the few Reproductive Immunologists in the country and is an active researcher with an interest in women older than 40 with Low Ovarian Reserve (low AMH or high FSH), Stem Cell ovarian rejuvenation, gentle stimulation IVF, natural IVF, and IVF without injectables. He was named “Top 2% Scientists in the World.”His research also focuses on technologies, such as Stem Cell Exosomes, Ozone Sauna therapy, and Low Level Laser Therapy (LLLT), that could improve egg quality especially in women with endometriosis, immune disorders, and PCOS. Dr. Merhi is also experienced in treating overweight women and those who had weight loss surgery. He is a strong proponent of the LGBTQ+ community and has proudly served the Arabic and Jewish Communities for over two decades.
If you've ever been told you're “too old,” your AMH is “too low,” your eggs are “gone,” or that donor eggs are your only option—you must listen to this episode.This is one of the most comprehensive, honest, science-based fertility conversations ever recorded.I sit down with one of the most innovative fertility specialists in the field to discuss breakthroughs that are changing possibilities for women at ANY age, including those with low ovarian reserve, recurrent loss, failed IVF cycles, or unexplained infertility.Today's guest is Dr. Zaher Merhi. Dr Merhi is the founder and the medical director of Rejuvenating Fertility Center (RFC). He is an internationally recognized fertility doctor, lecturer, editor, and grant reviewer. His training and faculty appointments included Albert Einstein College of Medicine/Montefiore Medical Center, NYU School of Medicine, and University of Vermont. He was a Professor at SUNY Downstate Health Sciences University and the Director of the Reproductive Endocrinology and Infertility (REI) Fellowship program (ACGME accredited). He is currently a Professor at Albert Einstein College of Medicine and Maimonides Medical Center in New York. He has 3 American Board certifications in OB/GYN, Reproductive Endocrinology and Infertility, and High-Complexity Laboratory Director (HCLD). Dr Merhi is one of the few Reproductive Immunologists in the country and is an active researcher with an interest in women older than 40 with Low Ovarian Reserve (low AMH or high FSH), Stem Cell ovarian rejuvenation, gentle stimulation IVF, natural IVF, and IVF without injectables. He was named “ONE OF THE TOP 2% SCIENTISTS IN THE WORLD.”For the first time publicly, you'll hear the truth about:✨ Environmental toxins are damaging eggs across generations✨ The rise of premature ovarian insufficiency✨ Microplastics found in the brain, ovaries & food supply✨ How inflammation drives aging, poor egg quality & failed implantation✨ Why diet absolutely impacts fertility (despite what many doctors say)✨ Cutting-edge ovarian rejuvenation options backed by published research✨ Stem-cell therapies are being used internationally to revive ovarian function✨ Why embryo testing is NOT black-and-white✨ The link between sperm DNA fragmentation & miscarriage✨ And why low AMH should NEVER be treated as an “infertility diagnosis”This conversation empowers couples with answers, hope, and real science—not fear.
This week, Dominique is joined by Dr. Evan Garfein, Chief of Plastic Surgery at Montefiore Medical Center and Professor of Surgery at the Albert Einstein College of Medicine. Together, they dive into one of the most important and often overlooked conversations in women's health: breast cancer, mastectomy, identity, and the power of choice in reconstruction.Dr. Garfein has dedicated his career to helping women restore both their bodies and confidence after breast cancer. With more than 60 peer-reviewed publications, three biomedical patents, and nearly a decade named in New York Magazine's Best Doctors, he is not only a surgeon but an advocate. He helped author a New York State law requiring doctors to inform women of their right to reconstruction, a crucial step toward bridging healthcare inequality.In this episode, Dominique and Dr. Garfein discuss:What inspired him to leave cardiac surgery and dedicate his life to breast reconstructionHow reconstruction has evolved from early muscle-flap techniques to modern options like implants and DIEP flapsThe emotional impact of mastectomy and why reconstruction is about more than appearanceThe critical importance of timing, radiation, and why women must speak to a plastic surgeon early in their diagnosisThe hidden inequality in breast cancer care, and his fight to make reconstruction information and access a legal right for all womenClarifying implant safety, longevity, and the truth behind breast implant illness and removal trendsFor more on Dr. Garfein, follow him on:Instagram: https://www.instagram.com/drevangarfein/?hl=en Website: https://evangarfeinmd.com/ LinkedIn: https://www.linkedin.com/in/evan-garfein-md-mba-800ba03/ This episode is brought to you by:Ritual: My listeners get early access to their Black Friday sale with 40% off your first month at Ritual.com/OVER50 Honeylove: Save 20% at honeylove.com/OVER50Clean Simple Eats: Visit https://glnk.io/73q00/dominique and use code FLOURISHING20 at checkout for 20% off your first orderRidge Wallet: Head to Ridge.com to get up to 47% off your order.Timeline Nutrition: Head to timeline.com/flourishing to get 20% off your order. Revolve: Shop at Revolve.com/FLOURISHING and use code FLOURISHING for 15% off your first order. #REVOLVEpartnerHollow Socks: Hollow Socks is having a Buy 3, Get 3 Free Sale. Head to Hollowsocks.com today for up to 50% off your order.Keep in Touch:Website: https://dominiquesachse.tv/Book: https://dominiquesachse.tv/book/Insta: https://www.instagram.com/dominiquesachse/Facebook: https://www.facebook.com/DominiqueSachse/TikTok: https://www.tiktok.com/@dominiquesachse?lang=enYouTube: https://www.youtube.com/@dominiquesachsetvHave a question for Dominique? Submit it here for a chance to have it answered on the show! https://forms.gle/MpTeWN1oKN8t18pm6 Interested in being featured as a guest? Please email courtney@dominiquesachse.tv We want to make the podcast even better. Help us learn how we can: https://bit.ly/2EcYbu4Please note that this episode may contain paid endorsements and advertisements for products and services. Individuals on the show may have a direct or indirect financial interest in products or services referred to in this episode.Produced by Dear Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Why does bipolar disorder exist? And what if bipolar disorder isn't just an illness, but also an evolutionary adaptation? Dr. Holly Swartz reveals the evolutionary secrets of bipolar disorder - from flexible circadian rhythms that once helped our ancestors survive, to the creativity and boldness often linked with mania.(0:00) Evolution(0:22) Circadian Control in Nature(1:43) Advantages of Flexible Biological Clocks(4:48) Risk-Taking & CreativityBipolar Explained is a new talkBD series spotlighting expert perspectives on the history, biology, and management of bipolar disorder.--Dr. Holly A. Swartz is Professor of Psychiatry at the University of Pittsburgh School of Medicine and President of the International Society of Bipolar Disorders (ISBD). She received her undergraduate degree from Harvard College, medical degree from Albert Einstein College of Medicine, and completed her psychiatric residency training at New York Hospital / Cornell University School of Medicine. Dr. Swartz's research focuses on understanding and optimizing treatments for mood disorders. She is well known for her work evaluating Interpersonal Psychotherapy (IPT) and Interpersonal and Social Rhythm Therapy (IPSRT) as treatments for depression and bipolar disorder. Her research focuses on the role of IPSRT and pharmacotherapy in the management of bipolar II depression and IPT in the management of maternal depression. She is engaged in collaborative projects to develop computational frameworks to model dyadic interpersonal behaviors in relation to psychotherapy process and outcomes and to understand neural correlates of change in chronotherapeutic behavioral interventions. Her research has been funded by the National Institute of Health, National Science Foundation, and the Brain and Behavior Research Foundation.
Have you ever felt the quiet pull to change everything you thought you were building? For Marty Ross-Dolen, that moment came on September 11, 2001. She had devoted her entire life to psychiatry, but as she watched the towers fall with her children nearby, something in her said it was time to let go. That decision set her on a new course — one that led to motherhood, teaching, and eventually a memoir that uncovered the silence of multi-generational grief. In this conversation, Marty shares what it means to step away from a lifelong identity and find a new one through writing and reflection. Why listening to the voice inside matters more than the expectations you were raised to follow How unspoken grief can ripple through generations and quietly shape a family’s story What happens when you allow yourself to change your mind, even after decades of commitment Marty’s journey is both personal and universal, a reminder that it’s never too late to begin again.
Love the episode? Send us a text!In this episode of Breast Cancer Conversations, host Laura Carfang sits down with Dr. Evan Garfein, Chief of Plastic Surgery at Montefiore Medical Center, Professor of Surgery at Albert Einstein College of Medicine, and Co-Founder of Greenwich Street Aesthetics. With more than 60 peer-reviewed publications, three biomedical patents, and a leadership role in shaping New York State's groundbreaking breast reconstruction equity law, Dr. Garfein brings unmatched insight into the intersection of medicine, policy, and patient empowerment.Together, Laura and Dr. Garfein unpack:How breast reconstruction has evolved—and where the field is headedWhat patients need to know about their rights, options, and insurance coverageThe real-world impact of legislation that expands access and equity in reconstructive careThe latest innovations in surgical techniques and materials that are reshaping outcomesThe emotional and psychological dimensions of reconstruction and recoveryWhether you're a patient, caregiver, or clinician, this conversation offers valuable guidance on making informed decisions and navigating the post-mastectomy journey with confidence.Attend a free virtual SurvivingBreastCancer.org program (support groups, yoga, medication, expressive writing, art expression, and more!):https://www.survivingbreastcancer.org/eventsSubscribe to our weekly newsletterhttps://www.survivingbreastcancer.org/subscribeFollow us on InstagramSurvivingBreastCancer.org: https://www.survivingbreastcancer.org/Breast Cancer Conversations: https://www.instagram.com/breastcancerconversations/Support our Podcast, every dollar counts!https://givebutter.com/0fCiEUSupport the showLatest News: Join our Tell Cancer To Go #TakeAHike October 25, 2025 fundraiser! It's free to sign up! Learn more and start your team! Become a Breast Cancer Conversations+ Member! Sign Up Now.
Host Tracey Spencer Walsh sits down with Dr. Lydia Soifer, a renowned language pathologist, teacher trainer, and founder of the Soifer Center, for a thought-provoking conversation on the intersection of language, learning, and teaching.With decades of experience in interdisciplinary clinical and educational settings, Dr. Soifer breaks down the science of language development and the practical strategies teachers and families need to support children with diverse learning needs.
Dr Irene Grant is an Infectious Disease specialist with expertise in infectious complications in the immunocompromised and unusual infections in the immunocompetent. In the 1980's, in the midst of the HIV/AIDS epidemic, she trained at Memorial Sloan-Kettering Cancer Center in New York City, under Dr. Donald Armstrong (former President of the Infectious Disease Society of America) where she acquired training in Microbiology and Hospital Infection Control. Thereafter she spent years in academic medicine as an Assistant Professor of Medicine at Albert Einstein College of Medicine (1988 – 2000) and later Clinical Assistant Professor of Medicine at New York Medical College, involved in teaching, clinical epidemiology, and research, while treating inner city patients in the HIV “epicenter” in the Bronx. Later, in private practice, she applied her experience investigating unusual illnesses to help her patients sick from hazardous indoor exposures. For the past 24 years, she has evaluated and treated hundreds of debilitated patients and families with environmentally proven hazardous microbial exposures, correlating the development of multi-system illness with hazardous exposures, the reliability of diagnostic tests, and efficacy of anti-fungal treatment.
Send us a textIn this inspiring episode, Anne E. Goldfeld, MD—physician-scientist, humanitarian, and recipient of the 2025 Jimmy and Rosalynn Carter Humanitarian Award—joins Marla Dalton, CAE, and William Schaffner, MD, to reflect on a remarkable career in medicine, science, and global health. From treating patients in refugee camps along the Thai-Cambodian border to conducting groundbreaking research at Harvard Medical School and Boston Children's Hospital, Goldfeld shares the path that led her to a career that is tackling 2 of the greatest epidemics of our time: tuberculosis and HIV/AIDS.Show NotesA native Californian, Dr. Goldfeld attended Brown University and the University of California, Berkeley, and earned her medical degree from Albert Einstein College of Medicine. She completed her internship and residency in internal medicine and a clinical fellowship in infectious diseases at the Massachusetts General Hospital followed by a postdoctoral research training in molecular biology at Harvard University. She is Professor of Medicine and Pediatrics at Harvard Medical School and a Senior Investigator in the Program in Cellular and Molecular Medicine at Boston Children's Hospital, where her research laboratory is located. She is also Professor of Immunology and Infectious Disease at the Harvard TH Chan School of Public Health and a physician in the infectious disease division of Brigham and Women's Hospital. On the frontlines of the TB and AIDS crises, Dr. Goldfeld co founded transformative treatment and research programs—bringing care to some of the world's most underserved populations—that have led to fundamental discoveries that have saved countless lives.Follow NFID on social media
It was a pleasure to sit down with Dr. Nir Barzilai for a conversation that turned out to be both lively and thought-provoking. His decades of research on centenarians, biological age, and the hallmarks of aging have shaped how we think about longevity—and what's possible when we start targeting aging itself, not just individual diseases. We get into the science behind why some people live 20–30 years longer and healthier, and what it means to measure the biological age of individual organs. But we also hit a few sparks—especially when it comes to nutraceuticals and the role of metformin in prevention. I don't agree with everything you'll hear, and I followed up with Dr. Barzilai afterward to unpack some of the more provocative claims. We may just need a second round for this one... stay tuned. Check out the show notes at www.drkarafitzgerald.com/fxmed-podcast/ for all the relevant links and resources. ~DrKF Check out the show notes at https://www.drkarafitzgerald.com/fxmed-podcast/ for the full list of links and resources. GUEST DETAILS Nir Barzilai M.D. Director of the Einstein Institute for Aging Research Professor of Medicine and Genetics President of the Academy for Health & Lifespan Research Website: https://einsteinmed.edu/faculty/484/nir-barzilai Email: nir.barzilai@einsteinmed.edu Dr. Nir Barzilai is a pioneer in aging science, known for his work on centenarians, the biology of aging, and the TAME trial. He is Director of the Institute for Aging Research at Albert Einstein College of Medicine and author of Age Later and has published over 330 papers. THANKS TO OUR SPONSORS DIAMOND DUTCH: https://dutchtest.com/for-providers Biotics Research: https://www.bioticsresearch.com/ GOLD Vibrant Wellness: https://www.vibrant-wellness.com/ OneSkin: http://oneskin.co/DRKARA EXCLUSIVE OFFERS FROM OUR SPONSORS Why MitoQ's mitochondria-targeting is a critical step for your healthspan and longevity strategy.https://tinyurl.com/4f8t7jt6 OneSkin: Get 15% off OneSkin with the code DRKARA at oneskin.co/DRKARA CONNECT with DrKF Want more? Join our newsletter here: https://www.drkarafitzgerald.com/newsletter/ Or take our pop quiz and test your BioAge! https://www.drkarafitzgerald.com/bioagequiz YouTube: https://tinyurl.com/hjpc8daz Instagram: https://www.instagram.com/drkarafitzgerald/ Facebook: https://www.facebook.com/DrKaraFitzgerald/ DrKF Clinic: Patient consults with DrKF physicians including Younger You Concierge: https://tinyurl.com/yx4fjhkb Younger You Practitioner Training Program: https://www.drkarafitzgerald.com/trainingyyi/ Younger You book: https://tinyurl.com/mr4d9tym Better Broths and Healing Tonics book: https://tinyurl.com/3644mrfw
if you have any feedback, please send us a text! Thank you!Dr. Jason Leong began his career as a night-shift nurse in the emergency department, quickly advancing to the role of charge nurse. Determined to further his impact in patient care, he went on to attend medical school at Albert Einstein College of Medicine in New York. He then completed a combined Internal Medicine and Anesthesiology residency at Stanford University, followed by advanced training in Critical Care Medicine and Cardiac Anesthesiology.Unique? Absolutely. But beyond his impressive credentials, Dr. Leong is an engaging and insightful conversationalist. In this episode of Vital Times, Dr. Ludwig Lin sits down with him for an in-depth discussion.
Is your pelvic floor holding you back — literally? This week on the Growing Older Living Younger podcast, Dr. Nicole Fleischmann joins Dr. Gillian Lockitch to shatter the myths surrounding women's pelvic health. Discover why “the second mouth” — your pelvic floor — is key to nervous system regulation, continence, and vitality as you age. Learn how pushing to pee could be damaging your body, why Kegels might not be the answer, and how a simple sniff can reconnect you with your core. This is a must-listen episode for every woman over 40 who wants to age with grace, strength, and confidence. Dr. Nicole Fleischmann is a board-certified urologist specializing in female pelvic medicine and reconstructive surgery. She earned her MD from SUNY Downstate and completed her training in urology at Albert Einstein College of Medicine, followed by a fellowship at NYU. With over 25 years of clinical experience, she currently directs the FPMRS program at White Plains Hospital Center and serves as Assistant Clinical Professor at Albert Einstein College of Medicine. Dr. Fleischmann is the author of The Second Mouth: One Woman's Journey to Decode a Hidden Language for a New Era of Women's Health. Her integrative approach blends science and somatic awareness, helping women reconnect mind and body for lifelong pelvic health. Episode Timeline 0:00 – Introduction Dr. Gillian introduces the podcast theme of aging youthfully and welcomes Dr. Nicole Fleischmann to discuss pelvic health, aging, and the nervous system. 4:00 – Why Dr. Fleischmann Wrote The Second Mouth Nicole shares her motivation: translating intuitive understanding into a narrative that reframes pelvic floor function as neurological and energetic, not just mechanical. 6:30 – Urinary Issues and Aging Discussion of prevalence: incontinence affects up to 80% of women by age 80. Why pelvic floor dysfunction is universal yet misunderstood. 8:30 – What Is Embodied Awareness? Nicole defines “interoception” — tuning in to how your body feels from the inside — and why it's critical to aging well. 10:40 – What is the Second Mouth? How the pelvic floor functions like a jaw and why “opening” it via breath awareness is crucial to urination and defecation. 14:00 – Dysfunctional Urination Explained Dr. Fleischmann describes the three common (and harmful) ways women urinate and how proper breathwork can retrain this system. 17:30 – Childhood Origins of Dysfunction How toilet training ingrains habits of pushing, setting the stage for adult dysfunction — and what neurological milestones are missed. 21:30 – The Medical Establishment's Blind Spot Nicole explains why mainstream urogynecology hasn't caught up and why breathwork offers a path beyond surgery and drugs. 23:30 – Why Not Kegels? A passionate critique of Kegels and chest breathing — and how both disrupt pelvic harmony and nervous system regulation. 26:30 – The Sniff Technique Demonstration of a simple sniffing maneuver to engage the diaphragm and drop the pelvic floor — a key to functional urination and core stability. 29:00 – Unconscious Behaviors and Structural Damage Exploring how daily habits like pushing to urinate can lead to prolapse and why posture and breath matter more than strength. 33:00 – The One Habit to Build Today Dr. Fleischmann's no-nonsense advice: stop sucking in your belly. Let it out to free your diaphragm and align your body for healthy aging. 36:00 – Takeaway Message Breath is the key to nervous system regulation. Awareness can't be explained — it must be felt. Learn more about Dr. Fleischmann's work thesecondmouthbook.com @drnicolefleischmann for TikTok, instagram, LinkedIn Action Steps: Download my EBook Guide: Guide to Building Back a Better Body Schedule a CALL with Dr. Gillian Lockitch. Join the GOLY Community: https://www.facebook.com/groups/growingolderlivingyounger
With the increase in the public's attention to all aspects of brain health, neurologists need to understand their role in raising awareness, advocating for preventive strategies, and promoting brain health for all. To achieve brain health equity, neurologists must integrate culturally sensitive care approaches, develop adapted assessment tools, improve professional and public educational materials, and continually innovate interventions to meet the diverse needs of our communities. In this BONUS episode, Casey Albin, MD, speaks with Daniel José Correa, MD, MSc, FAAN and Rana R. Said, MD, FAAN, coauthors of the article “Bridging the Gap Between Brain Health Guidelines and Real-world Implementation” in the Continuum® June 2025 Disorders of CSF Dynamics issue. Dr. Albin is a Continuum® Audio interviewer, associate editor of media engagement, and an assistant professor of neurology and neurosurgery at Emory University School of Medicine in Atlanta, Georgia. Dr. Correa is the associate dean for community engagement and outreach and an associate professor of neurology at the Albert Einstein College of Medicine Division of Clinical Neurophysiology in the Saul Korey Department of Neurology at the Montefiore Medical Center, New York, New York. Dr. Said is a professor of pediatrics and neurology, the director of education, and an associate clinical chief in the division of pediatric neurology at the University of Texas Southwest Medical Center in Dallas, Texas. Additional Resources Read the article: Bridging the Gap Between Brain Health Guidelines and Real-world Implementation Subscribe to Continuum®: shop.lww.com/Continuum Continuum® Aloud (verbatim audio-book style recordings of articles available only to Continuum® subscribers): continpub.com/Aloud More about the American Academy of Neurology: aan.com Social Media facebook.com/continuumcme @ContinuumAAN Host: @caseyalbin Guests: @NeuroDrCorrea, @RanaSaidMD Full episode transcript available here Dr Jones: This is Dr Lyell Jones, Editor-in-Chief of Continuum. This exclusive Continuum Audio interview is available only to you, our subscribers. We hope you enjoy it. Thank you for listening. Dr Albin: Hi all, this is Dr Casey Albin. Today I'm interviewing Dr Daniel Correa and Dr Rana Said about their article on bridging the gap between brain health guidelines and real-world implementation, which they wrote with Dr Justin Jordan. This article appears in the June 2025 Continuum issue on disorders of CSF dynamics. Thank you both so much for joining us. I'd love to just start by having you guys introduce yourselves to our listeners. Rana, do you mind going first? Dr Said: Yeah, sure. Thanks, Casey. So, my name is Rana Said. I'm a professor of pediatrics and neurology at the University of Texas Southwestern Medical Center in Dallas. Most of my practice is pediatric epilepsy. I'm also the associate clinical chief and the director of education for our division. And in my newer role, I am the vice chair of the Brain Health Committee for the American Academy of Neurology. Dr Albin: Absolutely. So just the right person to talk about this. And Daniel, some of our listeners may know you already from the Brain and Life podcast, but please introduce yourself again. Dr Correa: Thank you so much, Casey for including us and then highlighting this article. So yes, as you said, I'm the editor and the cohost for the Brain and Life podcast. I do also work with Rana and all the great members of the Brain Health Initiative and committee within the AAN, but in my day-to-day at my institution, I'm an associate professor of neurology at the Albert Einstein College of Medicine in the Montefiore Health System. I do a mix of general neurology and epilepsy and with a portion of my time, I also work as an associate Dean at the Albert Einstein College of Medicine, supporting students and trainees with community engagement and outreach activities. Dr Albin: Excellent. Thank you guys both so much for taking the time to be here. You know, brain health has really become this core mission of the AAN. Many listeners probably know that it's actually even part of the AAN's mission statement, which is to enhance member career fulfillment and promote brain health for all. And I think a lot of us have this kind of, like, vague idea about what brain health is, but I'd love to just start by having a shared mental model. So, Rana, can you tell us what do you mean when you talk about brain health? Dr Said: Yeah, thanks for asking that question. And, you know, even as a group, we really took quite a while to solidify, like, what does that even mean? Really, the concept is that we're shifting from a disease-focused model, which we see whatever disorder comes in our doors, to a preventative approach, recognizing that there's a tremendous interconnectedness between our physical health, our mental health, cognitive and social health, you know, maintaining our optimal brain function. And another very important part of this is that it's across the entire lifespan. So hopefully that sort of solidifies how we are thinking about brain health. Dr Albin: Right. Daniel, anything else to add to that? Dr Correa: One thing I've really liked about this, you know, the evolution of the 2023 definition from the AAN is its highlight on it being a continuous state. We're not only just talking about prevention of injury and a neurologic condition, but then really optimizing our own health and our ability to engage in our communities afterwards, and that there's always an opportunity for improvement of our brain health. Dr Albin: I love that. And I really felt like in this article, you walked us through some tangible pillars that support the development and maintenance of this lifelong process of maintaining and developing brain health. And so, Daniel, I was wondering, you know, we could take probably the entire time just to talk about the five pillars that support brain health. But can you give us a pretty brief overview of what those are that you outlined in this article? Dr Correa: I mean, this was one of the biggest challenges and really bundling all the possibilities and the evidence that's out there and just getting a sense of practical movement forward. So, there are many organizations and groups out there that have formed pillars, whether we're calling them seven or eight, you know, the exact number can vary, but just to have something to stand on and move forward. We've bundled one of them as physical and sleep health. So really encouraging towards levels of activity and not taking it as, oh, that there's a set- you know, there are recommendations out there for amount of activity, but really looking at, can we challenge people to just start growing and moving forward at their current ability? Can we challenge people to look at their sleep health, see if there's an aspect to improve, and then reassess with time? We particularly highlight the importance of mental health, whether it's before a neurologic condition or a brain injury occurs or addressing the mental health comorbidities that may come along with neurologic conditions. Then there's of course the thing that everyone thinks about, I think, with brain health in terms of is cognitive health. And you know, I think that's the first place that really enters either our own minds or as we are observers of our elder individuals in our family. And more and more there has been the highlight on the need for social interconnectedness, community purpose. And this is what we include as a pillar of social health. And then across all types of neurologic potential injuries is really focusing on the area of brain injury. And so, I think the area that we've often been focused as neurologists, but also thinking of both the prevention along with the management of the condition or the injury after it occurs. Dr Albin: Rana, anything else to add to that? That's a fantastic overview. Dr Said: Daniel, thank you for- I mean, you just set it up so beautifully. I think the other thing that maybe would be important for people to understand is that as we're talking through a lot of these, these are individual. These sound like very individual-basis factors. But as part of the full conversation, we also have to understand that there are some factors that are not based on the individual, and then that leads to some of the other initiatives that we'll be talking about at the community and policy levels. So, for example, if an individual is living in an area with high air pollution. Yes, we want them to be healthy and exercise and sleep, but how do we modify those factors? What about lead leaching from our aging pipes or even infectious diseases? So, I think that outside of our pillars, this is sort of the next step is to understand what is also at large in our communities. Dr Albin: That's a really awesome point. I love that the article really does shine through and that there are these individual factors, and then there there's social factors, there's policy factors. I want to start just with that individual because I think so many of our patients probably know, like, stress management, exercise, sleep, all of that stuff is really important. But when I was reading your article, what was not so obvious to me was, what's the role that we as neurologists should play in advocating? And really more importantly, like, how should we do that? And again, it struck me that there are these kind of two issues at play. And one is that what Daniel was saying that, you know, a lot of our patients are coming because they have a problem, right? We are used to operating in this disease-based care, and there's just limited time, competing clinical demands. If they're not coming to talk about prevention, how do we bring that in? And so Rana, maybe I'll start with you just for that question, you know, for the patients who are seeing us with a disease complaint or they're coming for the management of a problem, how are you organizing this at the bedside to kind of factor in a little bit about that preventative brain health? Dr Said: You know, I think the most important thing at the bedside is, one, really identifying the modifiable risk factors. These have been well studied, we understand them. Hypertension, diabetes, smoking, weight management. And we know that these definitely are correlative. So is it our role just to talk about stroke, or should we talk about, how are you managing your blood pressure? Health education, if there was one major cornerstone, is elevating health literacy for everyone and understanding that patients value clear and concise information about brain health, about modifiable risk factors. And the corollary to that, of course, are what are the resources and services? I completely understand---I'm a practicing clinician---the constraints that we have at the bedside, be it in the hospital or in our clinics. And so being the source of information, how are we referring our families and individuals to social workers, community health worker support, and really partnering with them, food banks, injury prevention programs, patient advocacy organizations? I think those are really ways that we can meet the impacts that we're looking at the bedside that can feel very tangible and practical. Dr Albin: That's really excellent advice. And so, I'd like to ask a follow-up question. With your knowledge of this, trying to get more multidisciplinary buy-in from your clinic so that you really have the support to get these services that are so critically important. And how do you do that? Dr Said: Yeah, I think it's, one, being a champion. So, what does a champion mean? It means that somebody has to decide this is really important. And I think we all realize that we're not the only ones in the room who care about this. We're all in this, and we all care about it. But how do we champion it and carry it through? And so that's the first. Second you find your partnerships: your social workers, your case managers, your other colleagues. And then what is the first-level entry thing that you can do? So for example, I'm a pediatric epileptologist. One of the things we know is that in pediatric epilepsy, depression and anxiety are very strong comorbidities. So, before we get to the point where a child is in distress, every single one of our epilepsy patients who walks in the door over the age of twelve has an age-appropriate screener that is given to them in both English and Spanish. And we assess it and we determine stratifying risk. And then we have our social workers on the back end and we decide, is this a child who needs resources? Is this a child who needs to be walked to the emergency room, escorted? And anything in between. And I think that that was a just a very tangible example of, every single person can do this and ask about it. And through the development of dot phrases and clear protocols, it works really well. Dr Albin: I love that, the way that you're just being mindful. At every step of the way, we can help people towards this lifelong brain health. And Daniel, you work with an adult population. So I wonder, what are your tips for bringing this to a different patient population? Dr Correa: Well, I think---adult or child---one thing that we often are aware of with so many of the other things that we're doing in bedside or clinic room counseling, but we don't necessarily think of in this context of brain health, is, remember all the people in the room. So, at the bedside, whether it's in the ICU, discharge counseling, the initial admission, the whole family is often involved and really concerned about the active issue. But you can look for opportunities- we often try to counsel and support families about the importance of their own sleep and rest and highlighting it not just as being there for their family member, but highlighting it to them as a measure of their own improvement of their brain health. So, looking at ways where, one, I try to find, is there something I can do to support and educate the whole family about their brain health? And then- and with an epilepsy, or in many other situations, I try to look for one comorbidity that might be a pillar of brain health to address that maybe I wasn't already thinking. And then I consider, is there an additional thing that they wouldn't naturally connect to their epilepsy or their headaches that I can bring in for them to work on? You know, we can't often give people twelve different things to work on, and they'd just feel like, okay like, you have no realistic understanding of my life. But if we can just highlight on one, and remind them that there can be many more ways to improve their health and to follow up either with us as their neurologist or their future primary care doctors to address those additional needs. Again, I would really highlight the importance of a multidisciplinary approach and looking for opportunities. We've too often, I feel, relied on primary care as being the first line for addressing unmet social health needs. We know that so many people, once they have a neurologic condition or the potential, even, of a neurologic condition, they're concerned about dementia or something, they may view us, as their neurologist, as their most important provider. And if they don't have the resource of time and money to show up at other doctors, we may be the first one they're coming to. And so, tapping into your institution's resources and finding out, are there things that are available to the primary care services that for some reason we're not able to get on the inpatient side or the outpatient side? Referring to social workers and care workers and showing that our patients have an independent need, that they're not somehow getting captured by the primary care doctors. Dr Albin: I really love that. I think that we- just being more invested and just being ready to step into that role is really important. I was noticing in this article, you really call that being a brain health ambassador, being really mindful, and I will direct all of our listeners to Figure 3, which really captures what practitioners can do both at the bedside, within their local community, and even at the professional society level, to really advocate for policies that promote brain wellness. Rana, at the very beginning of this conversation, you noted, you know, this is not just an individual problem. This really is something that is a component of our policy and the structure of our local communities. I really loved in the article, there's a humility that this cannot be just a person-by-person bedside approach, that this is a little bit determined by the social determinants of health. And so, Rana, can you walk us through a little bit of what are the social determinants of health, and why are these so crucially important when we think about brain health for all? Dr Said: Yeah, social determinants of health are a really key factor that it looks at, what are the health factors that are environmental; for example, that are not directly like what your blood pressure is, what, you know, what your BMI is, that definitely impact our health outcomes. So, these include environmental things like where people are born, where they live, where they learn, work, play, worship, and age. It encompasses factors like your socioeconomic status, your education, the neighborhoods where you are living, definitely healthcare access. And then all of this is in a social and community context. We know that the impact of social determinants of health on brain health are profound for the entire lifespan and that- so, for example, if someone is from a disadvantaged background or that leads to chronic stress, they can have limited access to healthcare. They can have greater risk of exposure to, let's say, environmental toxins, and all of that will shape how their brain health is. Violence, for example. And so, as we think about how we're going to target and enhance brain health, we really have to understand that these are vulnerable populations, special high-risk populations, that often have a disproportionate burden of neurologic disorders. And by identifying them and then developing targeted interventions, it promotes health equity. And it really has to be done in looking at culturally- ethnocultural-sensitive healthcare education resources, thinking about culturally sensitive or adaptive assessment tools that work for different populations so that these guidelines that we have, that we've already identified as being so valuable, can be equitably applied, which is one crucial component of reducing brain health risk factors. And lastly, at the neighborhood level, this is where we really rely on our partnerships with community partners who really understand their constituents and they understand how to have the special conversations, how to enhance brain health through resource utilization. And so, this is another plug for policy and resources. Dr Albin: I love that. And thinking about the neighborhood and the policy levels and all the things that we have to do. Daniel, I'd like to ask you, is there anything else you would add? Dr Correa: Yeah, you know, so I really wanted to come back to this thing is that often and unfortunately, in the beginning understanding of social determinants of health, they're thought of as a positive or a negative factor, and often really negative. These are just facts. They're aspects about our community, our society, and some of them may be at the individual level. They're not at fault of any individual or community, or even our society. They're just the realities. And when someone has a factor that may predict a health disparity or an unmet social need---I wanted to come back to that concept and that term---one or two positive factors that are social determinants of health for that individual are unmet social needs. It's a point of promise. It's a potential to be addressed. And seeking ways to connect them with community services, social work, caregivers, these are ways where- that we can remove a barrier to, so that the possibility of the recommendations that we're used to doing, giving recommendations about medications and management, can be fully appreciated for that person. And the other aspect is, like brain health, this is a continuous state. The social determinants of health may be different for the child, the parent, and the elderly family member in the household, and there might be some that are shared across them. And when one of those individuals has a new medical illness or a new condition, a stroke, and now has a mobility limitation, that may change a social determinant of health for that person or for anyone else in the family, the other people now becoming caregivers. We're used to this. And for someone after a stroke or traumatic brain injury, now they have mobility changes. And so, we work on addressing those. But thinking on how those things now become a barrier for engaging with community and accessing things, something as simple as their pharmacy. Dr Albin: I hear a lot of “this is a fluid situation,” but there's hope here because these are places that we can intervene and that we can really champion brain health throughout this fluid situation. Which kind of brings me to what we're going to close out with, which is, I'm going to have you do a little thought exercise, which is that you find a magic lamp and a genie comes out. And we'll call this the brain health genie. The genie says that they are going to grant you one wish for the betterment of brain health. Daniel, I'll start with you. What is the one thing that you think could really move the needle on promoting and maintaining brain health? Dr Correa: I will jump on nutrition and food access. If we could somehow get rid of food insecurity and have access to whole and fresh foods for everyone, and people could go back to looking at opportunities from their ancestral and cultural experiences to cook and make whole-food recipes from their own cultures. Using something like the Mediterranean diet and the mind diet as a framework, but not looking at those as cultural barriers that we somehow all have to eat a certain way. So, I think that would really be the place I would go to first that would improve all of our brain health. Dr Albin: I love that. So, wholesome eating. Rana, how about you? One magic wish. Dr Said: I think traumatic brain injury prevention. I think it's so- it feels so within our reach, and it just always is so heart-hurting when you think that wearing helmets, using seatbelts, practicing safety in sports, gun safety---because we know unfortunately that in pediatric patients, firearm injury is the leading cause of traumatic brain injury. In our older patients, fall reduction. If we could figure out how to really disseminate the need for preventative measures, get everyone really on board, I think this is- the genie wouldn't have to work too hard to make that one come true. Dr Albin: I love that. As a neurointensivist, I definitely feel that TBI prevention. We could talk about this all day long. I really wish we had a longer bit of time, but I really would direct all of our listeners to this fantastic article where you give really practical advice. And so again, today I've been interviewing Drs Daniel Correa and Rana Said about their article on bridging the gap between brain health guidelines and real-world implementation, written with Dr Justin Jordan. This article appears in the most recent issue of Continuum on the disorders of CSF dynamics. Be sure to check out Continuum Audio episodes from this and other issues. And thank you so much for our listeners for joining us today. Dr Monteith: This is Dr Teshamae Monteith, Associate Editor of Continuum Audio. We hope you've enjoyed this subscriber-exclusive interview. Thank you for listening.
In our July replay episode, Dr. Karinn Glover, an Assistant Professor of Psychiatry at the Albert Einstein College of Medicine, explored burnout, the unique stressors that healthcare workers face and resources that can help. In our July Key Note, Dr. Glover discusses the role empathy plays – tuning into others' feelings as well as our own – in building supportive relationships that are key to battling burnout. The Takeaway We want to hear from you! Please complete our survey: 1199SEIUBenefits.org/member-feedback Drop us a line at our social media channels: Facebook // Instagram // YouTube. Find a mental health therapist through the Benefit Funds' Provider Directory: www.1199SEIUBenefits.org/find-a-provider Connect with a therapist online through Teladoc: www.Teladoc.com or (800) TELADOC (835-2362). Visit the Healthy Minds section of our Healthy Living Resource Center for additional information and resources: www.1199SEIUBenefits.org/healthyminds For additional support, call our Wellness Member Assistance Program: (646) 473-6900. Contact our partners at the National Alliance on Mental Illness (NAMI) for a wide variety of community resources: www.naminycmetro.org . Reach out to the New York State Office of Mental Health Emotional Support Helpline at (844) 863-9314. Guest Bio Karinn Glover, MD, MPH, is an Assistant Professor of Psychiatry at the Albert Einstein College of Medicine, where she teaches psychopharmacology and aspects of psychotherapy to Psychiatry and Family Medicine residents. Her decade-plus experience as a psychiatrist and leader in the practice of integrated care and workplace mental health has informed her approach to health equity, Diversity, Equity, Inclusion and Belonging (DEI+B), and the styles of leadership that produce organizational success. Dr. Glover attended SUNY Downstate College of Medicine and obtained a Master of Public Health from Columbia University's Mailman School of Public Health via the highly competitive Macy Scholars Program.
In this conversation, I talk with neuropsychologist Lisa Rappaport about the realities of living with dyslexia—something she knows firsthand. We get into what dyslexia really is (and isn't), how awareness and support have evolved, and why early diagnosis and strong advocacy matter so much. Lisa shares insights from both her personal and professional experience, and we talk through ways parents can support their kids with dyslexia at home and in school. About Lisa Rappaport, PhD Lisa Rappaport, PhD, is a licensed psychologist in private practice in Manhattan with a specialty in working with and diagnosing learning disabilities. She has extensive training and experience in treating adults and children with dyslexia, attention deficit disorder, and anxiety disorders. In addition to her private practice, Dr.Rappaport is also on the faculty at the Rose F. Kennedy Center Children's Evaluation and Rehabilitation Center at the Children's Hospital at Montefiore, Albert Einstein College of Medicine. She lives in Manhattan. Things you'll learn from this episode Why early diagnosis and intervention are essential to support dyslexic children's learning and confidence How parental advocacy can play a powerful role in securing school accommodations and support Why stigma and misunderstanding around dyslexia can negatively impact self-esteem—and how to counter it How gaps in teacher training contribute to delays in recognizing and addressing dyslexia in the classroom How consistent support at home and school can help dyslexic children thrive academically and emotionally Resources mentioned Dr. Lisa Rappaport's website Parenting Dyslexia: A Comprehensive Guide to Helping Kids Develop Confidence, Combat Shame, and Achieve Their True Potential by Lisa Rappaport, PhD and Jody Lyons, MEd Parenting Dyslexia on Hachette Author Micki Boas on Advocating for Dyslexic Students (Full-Tilt Parenting) One in Five: How We're Fighting for Our Dyslexic Kids in a System That's Failing Them by Micki Boas Learn more about your ad choices. Visit podcastchoices.com/adchoices
The menstrual cycle is as regular as clockwork, or at least it should be. But for many adolescent patients, what should be a manageable monthly event turns into a full-blown disruptor of school, sports, sleep and sanity. As we explore the world of adolescent gynecology, we take a closer look at the intricate details: how cramps can hide endometriosis and ‘normal' isn't always what it seems. These symptoms are not just part of puberty. These are signals that deserve attention, validation, and thorough evaluation. This episode was recorded live on the exhibit floor at the 2025 Pediatric Academic Societies Conference in Honolulu, Hawaii. Joining us for this episode is Elizabeth Alderman, MD, Chief of the Division of Adolescent Medicine at The Children's Hospital at Montefiore. She is also a professor at the Albert Einstein College of Medicine. Some highlights from this episode include: First-line treatments for painful periods in adolescents Red flags in menstrual history that could lead to further concerns Primary care diagnostic steps before referring to gynecology How to create a comfortable environment for discussing these uncomfortable topics for adolescents Charting Pediatrics is in the running for a People's Choice Podcast Award, and we need your help to get nominated! Starting July 1, you can head to www.podcastawards.com and nominate us for the “science and medicine” category, as well as the “people's choice” category. Listeners like you are the reason we have become one of the top pediatric podcasts for providers around the world. Your nomination could make all the difference in us receiving this recognition! Nominate us by July 31st and help Children's Hospital Colorado lead the way in pediatric podcasting. Thank you for your support! For more information on Children's Colorado, visit: childrenscolorado.org.
In this special episode, host Chris Patil (VP-Media, BioAge) moderates a live panel discussion at the 25th Bay Area Aging Meeting at UCSF, bringing together six leading voices across the aging research ecosystem to tackle one of the field's most critical challenges: how to move promising discoveries from the laboratory to therapies that can benefit patients.The distinguished panel spans academia, industry, and scientific publishing, featuring Janine Sengstack (CEO, Junevity), Saul Villeda (Professor, UCSF), Jodi Nunnari (Director, Bay Area Institute of Science, Altos Labs), Sebastien Thuault (Chief Editor, Nature Aging), Anne Brunet (Professor, Stanford), and Nir Barzilai (Professor, Albert Einstein College of Medicine). Together, they explore the most promising research directions for clinical impact, the revolutionary tools enabling modern aging research, and the structural challenges that must be overcome to bring longevity therapies to market.Listeners will gain insights into the emerging science of cellular rejuvenation, the importance of systemic factors in aging, how to balance high-risk discovery with practical drug development, and the cultural shifts needed to better prepare the next generation of scientists for translational work. The panel also addresses the regulatory challenges of targeting aging itself as an indication and offers candid advice for young researchers navigating this rapidly evolving field.The Finer Details:Emerging research directions with the greatest clinical potential: cellular senescence, rejuvenation and repair, DNA methylation clocks, and understanding what makes aging biomarkers tickThe revolution in cellular and spatial resolution tools and how single-cell technologies are revealing cell-type-specific aging responsesSystemic factors and the remarkable plasticity remaining in aging organisms that can be unlocked through interventionsThe critical importance of starting with human data and working backward to validate targets and approachesChallenges unique to aging biotech: the need for aging-specific cellular assays, testing in older animal models, and genetic validationCultural and structural barriers between academia and industry, including the shift from mechanism-focused to mission-driven researchBalancing high-risk fundamental discovery with the practical needs of drug development and clinical translationThe regulatory landscape for aging interventions and potential pathways to FDA approval beyond traditional disease indicationsAdvice for young scientists: embracing rejection as part of the process, finding passion, working as teams, and considering diverse career paths in the growing longevity ecosystemQuotes:"Our goal as a company is to increase human health span, and the way I like to frame that more colloquially is we want to increase the number of happy, healthy years each person gets to spend on Earth." - Janine Sengstack"There is an exquisite amount of plasticity left in an aging organism, both within the tissues, within the cells. There is plasticity that we can actually tap into." - Saul Villeda"Burn bright, but don't burn out." - Jodi Nunnari"The challenge that we run into is that there are so many combinations that very quickly it would become intractable to line up enough test tubes to test them all." - Sebastien Thuault, on the complexity of aging interventions"We love our job. If not, we would not be doing it. I would do it again in a heartbeat... you get paid to play, to ask the questions that interest you, the approaches that interest you to play with who you want to—it is a fantastic job." - Saul Villeda"Our life is a life of rejection...and still, we're having fun and making an advance. So don't give up." - Nir Barzilai
Check out my top picks for skin care here. Why do so many of us avoid going to the doctor—even when we know we shouldn't? In this episode, Dr. Mina sits down with Dr. Manju Dawkins to unpack the deeply human fear that keeps patients away from the care they need. From needle phobia to fear of diagnosis, this conversation dives into the emotional blocks that sabotage our health and skin wellness. Together, they explore how to replace avoidance with empowerment, creating safer, more compassionate healthcare spaces. Dr. Dawkins shares data, clinical insights, and thoughtful approaches to addressing patient fear—helping listeners understand what's really behind the hesitation and how providers and patients alike can better navigate it. Key Takeaways: Fear of doctors is common and layered—often rooted in pain, past trauma, or fear of diagnosis. Over 60% of adults now report needle fear, up dramatically from past decades. Creating space in the exam room for vulnerability leads to better healthcare outcomes. The traditional “paternalistic” model of medicine is outdated; patient autonomy and understanding are now key. Transparency in healthcare—like doctors on social media—can reduce anxiety and increase trust. Addressing fear can improve everything from skin health to early diagnosis and treatment of serious conditions. Dr. Manju Dawkins is a board certified dermatologist who received her B.A. from Columbia University and her M.D. from the University of Maryland. She completed her dermatology residency and served as Chief Resident at Albert Einstein College of Medicine in the Bronx, NY. She was Assistant Professor at Mount Sinai School of Medicine where she was twice named Teacher of the Year. She has practiced in academic, private, hospital based, and group practice settings in New York and Los Angeles. She is also the creator and co-founder of Thimble, the first easy, safe, and comprehensive solution for alleviating needle pain and stress. www.thimblehealth.com Fun fact: She is 5'2" (on a good day. ) Even more fun fact: She played Division I basketball at Columbia University and served as captain her senior year. She is a founding and current member of the Columbia Women's Basketball Advisory Board and a member of the Columbia Athletics Women's Leadership Council. Follow Dr. Dawkins here: https://www.instagram.com/thimble.health/ https://www.linkedin.com/company/thimblehealth/ https://www.linkedin.com/in/manju-dawkins-md-a0224359/ http://thimblehealth.com/ https://www.tiktok.com/@thimble.health https://www.facebook.com/thimble.health
Listen as we talk about recognizing burnout with Dr. Karinn Glover, a board-certified physician and psychiatrist and clinician with Montefiore Health System. Dr. Glover helps us examine the unique stressors that healthcare workers face, the symptoms of burnout and when to ask for help. She offers insights and strategies for getting the support you need, from DIY remedies like self-care to professional care and how to find it. Dr. Glover also runs down some outside influences that can contribute to burnout and what you can do to overcome them. The Takeaway Find a mental health therapist through the Benefit Funds' Provider Directory: www.1199SEIUBenefits.org/find-a-provider. Connect with a therapist online through Teladoc: www.Teladoc.com or (800) TELADOC (835-2362). Visit the Healthy Minds section of our Healthy Living Resource Center for additional information and resources: www.1199SEIUBenefits.org/healthyminds/ For additional support, call our Wellness Member Assistance Program: (646) 473-6900. Contact our partners at the National Alliance on Mental Illness (NAMI) for a wide variety of community resources: www.naminycmetro.org. Reach out to the New York State Office of Mental Health Emotional Support Helpline at (844) 863-9314. Guest Bio Karinn Glover, MD, MPH, is an Assistant Professor of Psychiatry at the Albert Einstein College of Medicine, where she teaches psychopharmacology and aspects of psychotherapy to Psychiatry and Family Medicine residents. Her decade-plus experience as a psychiatrist and leader in the practice of integrated care and workplace mental health has informed her approach to health equity, Diversity, Equity, Inclusion and Belonging (DEI+B), and the styles of leadership that produce organizational success. Dr. Gloverattended SUNY Downstate College of Medicine and obtained a Master of Public Health from Columbia University's Mailman School of Public Health via the highly competitive Macy Scholars Program.
On this episode of Newly Erupted, host Dr. Joel Berg talks about the keys to avoiding burnout with Dr. Trudy-Ann Frazer. Dr. Frazer shares her three-step approach to mitigating burnout, particularly for female practitioners and what steps to take once you realize burnout has taken hold – either in yourself or your team. Guest Bio: Dr. Trudy-Ann Frazer has experience working exclusively with children. It is her goal to promote good oral habits to children and parents as a part of preserving beautiful, healthy smiles for a lifetime. She earned her DDS from Meharry Medical College in Nashville, Tennessee as the Valedictorian, then completed her certificate in Pediatric Dentistry residency from the Albert Einstein College of Medicine/ Montefiore Medical Center in the Bronx, New York. She is a proud graduate of Oakwood University in Huntsville, Alabama where she received her Bachelor of Science in Biology. Dr. Frazer was born in Negril, Jamaica and grew up in Stone Mountain, Georgia. She has dedicated much of her professional career to educating and serving children and participated in numerous outreach activities, which include several mission trips to offer dental services to children in Jamaica. She is also involved in various organizations, including the American Academy of Pediatric Dentistry, American Dental Association, and National Dental Association, as well as a diplomate of the American Board of Pediatric Dentistry. She enjoys swimming, basketball, camping, traveling and spending quality time with her family and friends.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
The Theology, Medicine, and Culture Initiative (TMC) welcomed Dr. Elaine Eng for this virtual seminar on October 27, 2023. Elaine Eng, M.D., is a graduate of Princeton University and the Albert Einstein College of Medicine. She is a professor of mental health counseling who integrates faith, medicine, and psychology in her international and local work as an educator, psychiatrist, and author. Dr. Eng was diagnosed with retinitis pigmentosa in hear adulthood. Her impending blindness meant that she would no longer be able to practice as an obstetrician/gynecologist. Dr. Eng shares a compelling story of faith and commitment to medicine amidst adversity in this virtual seminar. Dr. Eng's books include "The Transforming Power of Story: How Telling Your Story Brings Hope to Others and Healing to Yourself," and "A Christian Approach to Overcoming Disability: A Doctor's Story."
The former Director of Ohio's Department of Health, Amy Acton, M.D., MPH was the first Democratic candidate to announce a campaign for Ohio Governor. Dr. Acton was nominated Director of Ohio's Department of Health by Governor Mike DeWine in February 2019. She quickly became a household name, joining Governor DeWine during his daily afternoon press conferences in the early days of the COVID-19 pandemic.rnrnDr. Acton began her career as the Director of Project L.O.V.E, managing public-private partnerships between Columbus area hospitals and key community stakeholders. Amy then joined the faculty at Ohio State University, and eventually joined the Columbus Foundation, where she worked to improve the community's health and well-being, particularly in the area of women's health and youth homelessness.rnrnDr. Acton received her medical degree from Northeastern Ohio University College of Medicine and completed her internship and residency training in pediatrics at Albert Einstein College of Medicine in New York City, and at Nationwide Children's Hospital in Columbus. Dr. Acton lives in Bexley, Ohio with her husband Eric, and together they have six kids.
Marty Ross-Dolen joins Let's Talk Memoir for a conversation discovering the story while writing, inviting the speculative and magical elements into a narrative, rediscovering lost relatives, advocating for our vision and for our books, scaffolding fragmented forms, being raised by a mother in protracted mourning, incorporating letters, photographs, and erasure poetry, when people tell you what your book is supposed to be, living with an inherited sense of grief, unspoken family pacts, when structure is a surprise, and her new memoir Always There, Always Gone: A Daughter's Search for Truth. Also in this episode: --being raised in silence around a tragedy -telling 3 stories at once -memoir as erasure Books mentioned in this episode: -Safekeeping by Abigail Thomas -Another Bullshit Night in Suck City by Nick Flynn -Ghostbread by Sonja Livingston -Disconto for My Father by Harrison Kandelaria Fletcher -Fearless Confessions by Sue William SIlverman Marty Ross-Dolen is a graduate of Wellesley College and Albert Einstein College of Medicine and is a retired child and adolescent psychiatrist. She holds an MFA in Writing from Vermont College of Fine Arts. Prior to her time at VCFA, she participated in graduate-level workshops at The Ohio State University. Her essays have appeared in North Dakota Quarterly, Redivider, Lilith, Willow Review, and the Brevity Blog, among others. Her essay entitled “Diphtheria” was named a notable essay in The Best American Essays series. She teaches writing and lives in Columbus, Ohio. Connect with Marty: Website: www.martyrossdolen.com Instagram: https://www.instagram.com/martyrossdolen Get the book: https://a.co/d/5HtWU4s https://www.thurberhouse.org/adult-writers-studio – Ronit's writing has appeared in The Atlantic, The Rumpus, The New York Times, Poets & Writers, The Iowa Review, Hippocampus, The Washington Post, Writer's Digest, American Literary Review, and elsewhere. Her memoir WHEN SHE COMES BACK about the loss of her mother to the guru Bhagwan Shree Rajneesh and their eventual reconciliation was named Finalist in the 2021 Housatonic Awards Awards, the 2021 Indie Excellence Awards, and was a 2021 Book Riot Best True Crime Book. Her short story collection HOME IS A MADE-UP PLACE won Hidden River Arts' 2020 Eludia Award and the 2023 Page Turner Awards for Short Stories. She earned an MFA in Nonfiction Writing at Pacific University, is Creative Nonfiction Editor at The Citron Review, and teaches memoir through the University of Washington's Online Continuum Program and also independently. She launched Let's Talk Memoir in 2022, lives in Seattle with her family of people and dogs, and is at work on her next book. More about Ronit: https://ronitplank.com Subscribe to Ronit's Substack: https://substack.com/@ronitplank Follow Ronit: https://www.instagram.com/ronitplank/ https://www.facebook.com/RonitPlank https://bsky.app/profile/ronitplank.bsky.social Background photo credit: Photo by Patrick Tomasso on Unsplash Headshot photo credit: Sarah Anne Photography Theme music: Isaac Joel, Dead Moll's Fingers
Today we are delighted to welcome Dr. Erin Smith and Dr. Timothy Imafidon Jr, passionate art collectors and owners of Goldsboro Pediatric Dentistry and Orthodontics. Originally from Greensboro, North Carolina, Dr . Erin Smith completed her undergraduate education at Duke University in Durham. After her graduation she earned her Doctorate from Howard University before heading south to continue her training at Jacksonville University School of Orthodontics, earning certification in Orthodontics and Maxillofacial Orthopedics. Professionally, Dr . Smith is a member of the American Association of Orthodontists, American Dental Association, and the National Dental Association. Personally, she is a proud member of Delta Sigma Theta Sorority, Incorporated. Dr. Timothy Imafidon Jr . is a Board Certified pediatric dentist who was born in High Point, North Carolina. Growing up, he called North Carolina, Ohio and Indonesia home before heading off to Guilford College in Greensboro where he received his Bachelor of Science degree in Biology. Following college, Dr. Imafidon completed four additional years of dental school at Howard University in Washington D.C. before completing a two-year residency program at Jacobi Medical Center, a teaching hospital affiliated with Albert Einstein College of Medicine in New York. While in N.Y . he received extensive training in treating special needs and medically compromised children at the Rose F. Kennedy Center for Developmental Disabilities. He is a member of the North Carolina Dental Society, the American Academy of Pediatric Dentistry and the American Dental Association. He is a proud member of Kappa Alpha Psi. In this episode of The Art Elevator podcast, Sarah Reeder and Larissa Wild speak with Dr. Erin Smith and Dr. Timothy Imafidon Jr. about their journey in collecting art. I Topics discussed: - How to start educating yourself on the type of art you are interested in - Their tips on how to start a collection - How their collecting focus on African American art has influenced their friends, family and clients - The importance of supporting artists whose work speaks to you - The joy of living surrounded by art You can read more in the show notes here: https://larissawild.com/post/13416-the-art-elevator-episode-48---insights-on-collecting
In our May episode, we marked Hypertension Awareness Month with Dr. Robert Ostfeld, a cardiologist at Montefiore Medical Center. Dr. Ostfeld shared how his patients naturally lowered their blood pressure by adopting a plant-based diet and offered tips for eating more plant-based foods. In this month's Key Note, he explains how getting proper sleep can reduce stress hormones that contribute to high blood pressure. The Takeaway We want to hear from you! Please complete our survey: org/member-feedback. Drop us a line at our social media channels: Facebook// Instagram // YouTube. Get started on your health journey by making an appointment with your primary care physician to know your numbers. Get to know your numbers at 1199SEIUBenefits.org/healthyhearts. Find healthy recipes and meal-prep tips at 1199SEIUBenefits.org/food-as-medicine. Visit the Healthy Living Resource Center for wellness tips, information and resources; 1199SEIUBenefits.org/healthyliving. Get inspired by fellow members through our Members' Voices series: 1199SEIUBenefits.org/healthyliving/membervoices. Stop by our Benefits Channel to join webinars on building healthy meals, managing stress and more: 1199SEIUBenefits.org/videos. Visit our YouTube channel to view a wide collection of healthy living videos: youtube.com/@1199SEIUBenefitFunds/playlists. Sample our wellness classes to exercise body and mind: 1199SEIUBenefits.org/wellnessevents. Robert Ostfeld, MD, MSc, FACC, is the Director of Preventive Cardiology at Montefiore Health System and a Professor of Medicine at the Albert Einstein College of Medicine. Dr. Ostfeld treats patients with adult cardiovascular disease, including coronary artery disease, hypertension, hyperlipidemia and erectile dysfunction with a focus on prevention and treatment through lifestyle change. He works closely with his patients to help them adopt a plant-based diet. Dr. Ostfeld received his Bachelor of Arts in the Biologic Basis of Behavior from the University of Pennsylvania, graduating Summa Cum Laude and Phi Beta Kappa and his Doctor of Medicine from Yale University School of Medicine. He then did his medical internship and residency at the Massachusetts General Hospital and his Cardiology Fellowship and Research Fellowship in Preventive Medicine at Brigham and Women's Hospital, both teaching hospitals of Harvard Medical School. During his Cardiology Fellowship, he earned a Master's of Science in Epidemiology from the Harvard School of Public Health. Dr. Ostfeld's research focus is on cardiovascular disease prevention and reversal through lifestyle modification. Ongoing topics he investigates include the impact of plant-based nutrition on erectile function, coronary artery disease, angina and heart failure. His work has been published in peer-reviewed journals, books, articles, and clinical statements and has been presented nationally. Dr. Ostfeld is board certified in Cardiovascular Disease and Echocardiography, and he is a member of numerous professional societies, including the Physician's Committee for Responsible Medicine and the American College of Cardiology.
Topics covered in this episode: What is the pelvic floor? Why toilet posture is at the root of pelvic floor dysfunction. The guarding reflex, bladder and bowel dysfunction. Why real or perceived stress impacts your bowel and bladder dysfunction. How big a problem is pelvic floor dysfunction? And more ... Dr. Fleischmann is board certified in urology and Female Pelvic Medicine and Reconstructive Surgery. She received her medical degree from the State University of New York Downstate Health Sciences University in Brooklyn, NY, where she graduated summa cum laude. Dr. Fleischmann completed her surgery and urology residency at Albert Einstein College of Medicine in Bronx, NY and continued her training in a fellowship at NYU School of Medicine. She is passionate about practicing an integrative approach to urogynecology, correcting the pervasive, unconscious and paradoxical behaviors which can turn into the structural problems and bothersome symptoms that prompt women to seek care. She is the author of the new book “The Second Mouth”, which addresses the powerful mind-body connection in functional urology. Dr. Fleischmann serves as Director of FPMRS at White Plains Hospital Center where she has been in clinical practice for the last 25 years. She holds an active appointment as Assistant Clinical Professor in Obstetrics and Assistant Clinical Professor of Gynecology and Urology at Albert Einstein College of Medicine. Additionally, she is a member of the American Urologic Association and Society for Urodynamics and Female Urology (SUFU). Dr. Fleischmann is the author of several research publications and presentations. She lives and practices in New York. @drnicolefleischmann Thesecondmouthbook.com
Episode Overview: In this captivating episode of the Higher Density Living Podcast, host Jason Rigby sits down with Dr. Rick Strassman, a world-renowned psychedelic researcher and author of the groundbreaking book DMT: The Spirit Molecule. Known for his pioneering clinical research on DMT and his deep explorations into altered states of consciousness, Dr. Strassman brings a unique perspective to the table as he dives into the Book of Genesis. Together, they explore the intersections of biblical narratives, Jewish tradition, and the spiritual insights gleaned from his decades of psychedelic and personal inquiry. From the creation accounts to the Fall, the Flood, and the Tower of Babel, this episode unpacks Genesis through a lens that blends science, spirituality, and prophetic wisdom. Dr. Strassman shares his journey from Zen Buddhism to Judaism, his literal approach to interpreting biblical texts, and how his DMT research informs his understanding of human consciousness and divine interaction. Whether you're a spiritual seeker, a psychedelics enthusiast, or simply curious about the deeper meanings of Genesis, this episode offers a thought-provoking and enriching discussion. Meet Dr. Rick Strassman Born in 1952 in Los Angeles, California, Dr. Rick Strassman is a clinical psychiatrist, psychedelic researcher, and author whose work has reshaped our understanding of consciousness. After graduating with honors from Stanford University in biological sciences and earning his medical degree from Albert Einstein College of Medicine, he built a distinguished career in psychiatry and psychopharmacology. His groundbreaking DMT studies at the University of New Mexico in the 1990s marked the first U.S.-approved psychedelic research in over two decades, earning him global recognition. Dr. Strassman's books, including DMT: The Spirit Molecule (a quarter-million copies sold and translated into over a dozen languages) and DMT and the Soul of Prophecy, bridge science and spirituality. His latest work, My Altered States (December 2024), is an illustrated memoir exploring his personal experiences with altered states from birth to early adulthood. Currently a Clinical Associate Professor of Psychiatry at the University of New Mexico School of Medicine, Dr. Strassman resides in Gallup, New Mexico, where he continues to write and consult for psychedelic startups. Connect with Dr. Strassman: Website: rickstrassman.com Books: Amazon Author Page Joe Rogan Appearances: 2022 Episode | Earlier Episode Key Topics Discussed: 1. Genesis Through a Jewish Lens Dr. Strassman shares how his return to Jewish texts after leaving Zen Buddhism in 1996 shaped his understanding of Genesis. Raised in a conservative Jewish household, he re-engaged with the Hebrew Bible as an adult, finding parallels between the vivid experiences of his DMT volunteers and the prophetic visions of biblical figures. Two Creation Narratives: Genesis 1 offers a cosmic, orderly account, while Genesis 2 zooms into a detailed, human-focused story. Dr. Strassman views them as complementary—an overview followed by specifics—reflecting a divine act of creation from nothing. Divine Order and Cause-and-Effect: He explores how Genesis reveals God's nature through the laws of cause and effect, suggesting that nature itself mirrors divine will. 2. The Fall: Free Will and Consciousness The conversation delves into Adam and Eve's disobedience, which Dr. Strassman frames as the first exercise of free will with explicit consequences. He challenges the notion of the fruit as a psychedelic, instead emphasizing its role in shifting human perception from truth to the duality of good and evil. Shabbat as Eternal Rest: Jason raises the idea of the Sabbath lacking an “evening and morning” close, hinting at an eternal state. Dr. Strassman connects this to emulating God's rest, though he notes the Hebrew Bible avoids afterlife specifics. 3. Cain, Abel, and the Flood: Sin as a Virus From Cain's envy-driven murder of Abel to the violence (Hebrew: Hamas) preceding the Flood, Dr. Strassman sees these stories as literal events encoding lessons about human nature and societal decay. The Flood, he suggests, was a divine reset prompted by humanity's failure to align with God's intent. Sons of Elohim: Theories range from angels to elites interbreeding with humans, disrupting divine order. Dr. Strassman remains open but grounded in the text's ambiguity. 4. Tower of Babel: Misunderstood Ambition Dr. Strassman offers a fresh take on the Tower of Babel, arguing it's less about hubris and more about humanity's refusal to disperse post-Flood as God commanded. The scattering, he posits, fulfilled an original divine plan, with the tower as a symbol of misdirected unity. 5. Abraham's Covenant and Monotheism The patriarchal narratives (Genesis 12–50) shift focus to Abraham, Isaac, Jacob, and Joseph. Dr. Strassman highlights Abraham's call as a pivotal revelation of monotheism, questioning why Abraham was chosen—a mystery deepened by Midrashic tales of his iconoclastic zeal. Egypt's Role: He attributes Egypt's prominence to its cultural dominance, akin to the modern U.S., rather than mystical significance. 6. Prophecy, Psychedelics, and the Living Word Drawing from his DMT research, Dr. Strassman theorizes that prophetic visions might stem from endogenous DMT spikes, serving as a bridge for divine communication. He views Genesis as a prophetically received text, resonating with readers through its altered-state origins. Is the Bible Living? While Jason sees it as God's living word, Dr. Strassman approaches it as a guidebook to cause and effect, enduringly relevant but not inherently “alive” beyond its influence. 7. From Zen to Judaism Dr. Strassman reflects on his shift from Zen Buddhism—where he felt alienated by iconography—to Judaism's monotheistic grounding. This transition, sparked by personal and professional changes, led him to a more literal, grounded study of biblical texts. Memorable Quotes On DMT and Reality: “When volunteers said it felt ‘more real than real,' I learned to take it at face value—it opened up the strangest, most fascinating parts of their experiences.” On Genesis: “If you assume it's real, you can enter its world and learn what it's like. It's complex and rich in ways you miss if you see it as just archetypes.” On Prophecy: “The Hebrew Bible's appeal lies in its prophetic state—it's like reading a text that tingles with divine resonance.” On Monotheism: “It's not about whether it's wise—it's about whether it's true.” Why You Should Listen This episode is a rare fusion of psychedelic science and biblical exegesis, offering fresh insights into Genesis from a thinker who's explored both the outer edges of consciousness and the depths of Jewish tradition. Dr. Strassman's literal yet open-minded approach challenges conventional interpretations, making this a must-listen for anyone interested in spirituality, human potential, or the mysteries of existence. Resources & Links Books by Dr. Rick Strassman: DMT: The Spirit Molecule – Buy on Amazon DMT and the Soul of Prophecy – Buy on Amazon My Altered States (Dec 2024) – Buy on Amazon Joe Rogan Episodes: 2022 Interview Earlier Interview Dr. Strassman's Website: rickstrassman.com Call to Action Enjoyed this deep dive into Genesis with Dr. Rick Strassman? Subscribe to the Higher Density Living Podcast for more thought-provoking conversations. Share this episode with friends, leave a review, and grab Dr. Strassman's books to explore his groundbreaking work further. Let us know your thoughts in the comments—what's your take on Genesis as a living text?
For Hypertension Awareness Month, we are fortunate to have Dr. Robert Ostfeld, a cardiologist at Montefiore Medical Center, join us to talk about lifestyle approaches for treating – and preventing – high blood pressure. In this episode, Dr. Ostfeld explains the numbers, the symptoms – or lack of symptoms – and the associated risks. A self-confessed “reformed cardiologist,” he talks about how he saw his patients who adopted a plant-based diet significantly lower their blood pressure. Not ready to go totally plant-based? Dr. Ostfeld says simply adding more fruits, vegetables and whole grains to your diet can help lower not only your blood pressure but also your risk for heart disease, stroke and dozens of other conditions. The Takeaway We want to hear from you! Please complete our survey: org/member-feedback. Drop us a line at our social media channels: Facebook// Instagram // YouTube. Get started on your health journey by making an appointment with your primary care physician to know your numbers. Get to know your numbers at 1199SEIUBenefits.org/healthyhearts. Find healthy recipes and meal-prep tips at 1199SEIUBenefits.org/food-as-medicine. Visit the Healthy Living Resource Center for wellness tips, information and resources; 1199SEIUBenefits.org/healthyliving. Get inspired by fellow members through our Members' Voices series: 1199SEIUBenefits.org/healthyliving/membervoices. Stop by our Benefits Channel to join webinars on building healthy meals, managing stress and more: 1199SEIUBenefits.org/videos. Visit our YouTube channel to view a wide collection of healthy living videos: youtube.com/@1199SEIUBenefitFunds/playlists. Sample our wellness classes to exercise body and mind: 1199SEIUBenefits.org/wellnessevents. Robert Ostfeld, MD, MSc, FACC, is the Director of Preventive Cardiology at Montefiore Health System and a Professor of Medicine at the Albert Einstein College of Medicine. Dr. Ostfeld treats patients with adult cardiovascular disease, including coronary artery disease, hypertension, hyperlipidemia and erectile dysfunction with a focus on prevention and treatment through lifestyle change. He works closely with his patients to help them adopt a plant-based diet. Dr. Ostfeld received his Bachelor of Arts in the Biologic Basis of Behavior from the University of Pennsylvania, graduating Summa Cum Laude and Phi Beta Kappa and his Doctor of Medicine from Yale University School of Medicine. He then did his medical internship and residency at the Massachusetts General Hospital and his Cardiology Fellowship and Research Fellowship in Preventive Medicine at Brigham and Women's Hospital, both teaching hospitals of Harvard Medical School. During his Cardiology Fellowship, he earned a Master's of Science in Epidemiology from the Harvard School of Public Health. Dr. Ostfeld's research focus is on cardiovascular disease prevention and reversal through lifestyle modification. Ongoing topics he investigates include the impact of plant-based nutrition on erectile function, coronary artery disease, angina and heart failure. His work has been published in peer-reviewed journals, books, articles, and clinical statements and has been presented nationally. Dr. Ostfeld is board certified in Cardiovascular Disease and Echocardiography, and he is a member of numerous professional societies, including the Physician's Committee for Responsible Medicine and the American College of Cardiology.
Welcome to Perimenopause WTF!, brought to you by Perry—the #1 perimenopause app and safe space for connection, support, and new friendships during the menopause transition. You're not crazy, and you're definitely not alone! Download the free Perry App on Apple or Android and join our live expert talks, receive evidence-based education, connect with other women, and simplify your perimenopause journey.Today's Episode“From Medical to Lifestyle: Building Your Perimenopause Weight Loss Toolbox ”Weight gain during perimenopause and menopause is a huge concern for women; a real source of frustration. There are reasons behind it, oftentimes, hormonal reasons during this season as Dr. Disha Narang and Dr. Rocio Salas-Whalen explain. Listen in as they discuss why this happens to women and the various ways one can combat the dreaded visceral fat and weight gain!Discover What's New at Perry!Whether you're navigating perimenopause or empowering others as a women's health professional, Perry has something for you. Explore our latest features:
Welcome to MIGS Front Page episode our new host, Dr. Richard Hsu.In this episode, we are thrilled to feature our distinguished guest who is shaping the landscape of minimally invasive gynecologic surgery,Dr. Emily Wang, Assistant Professor of Obstetrics and Gynecology at Albert Einstein College of Medicine and Montefiore Medical Center. Dr. Wang shares her inspiring journey across diverse medical communities and discusses her groundbreaking research on endometriosis and surgical complications. Her insights into perioperative risks and multidisciplinary care provide valuable guidance for gynecologists navigating complex cases.Connect with the JMIG Social Media Team!X: @AAGLJMIGInstagram: @AAGLJMIGFacebook: AAGLJMIG
Dr. Catherine Oseni, Pharm.D., FAAMFM, ABAAHP Dr. Catherine Oseni is a board-certified, fellowship-trained clinical integrative pharmacist with deep expertise in both traditional pharmaceuticals and the impact of supplements and herbs on the body. Her career is rooted in a unique understanding of how conventional medications interact with integrative therapies, allowing her to create safe, personalized, and effective treatment plans for her clients. Since 2006, Dr. Oseni has provided direct client care, skillfully blending Western medicine with holistic, evidence-based approaches to address the root causes of health concerns. Her individualized care model focuses on achieving optimal wellness through natural, whole-person solutions. Recognized by peers as a leader in functional and integrative medicine, Dr. Oseni remains at the forefront of her field by continually expanding her knowledge through ongoing education and participation in professional conferences. She is also a passionate educator, frequently speaking at national and local events for both the public and healthcare professionals to promote and advance the field of integrative medicine. Dr. Olusegun Oseni, MD Dr. Olusegun Oseni serves as the Medical Director of Alpha Care Wellness Center and is board certified in internal medicine, pulmonary care, critical care, and sleep medicine. Originally from Nigeria, he earned his medical degree from the University of Ilorin College of Medicine before moving to the United States for postgraduate training. He completed his residency in internal medicine and a fellowship in pulmonary medicine at Harlem Hospital Center (an affiliate of Columbia University), followed by a fellowship in critical care medicine at Montefiore Medical Center (an affiliate of Albert Einstein College of Medicine), both in New York City. Dr. Oseni is a Fellow of the American College of Chest Physicians (FCCP), a Diplomate of the American Board of Sleep Medicine (DABSM), and an active member of the Society of Critical Care Medicine, American Lung Association, and American Medical Association. Highly respected by his peers and beloved by his patients, Dr. Oseni is known in the community for his thorough, compassionate care and unwavering commitment to improving quality of life—regardless of the complexity of the condition.
Send us a textOn this episode we speak with Dr. Jesse Goodman about the spread of the H5N1 virus. We will discuss what a virus is, how viruses migrate from animal populations to humans and assess the chances for a new pandemic.Jesse L. Goodman, M.D., M.P.H., directs Georgetown COMPASS, which focuses on science based policy and research to address unmet public health needs with an emphasis on product development and access and antimicrobial resistance and stewardship. Until February 2014 he served as the Chief Scientist of the US Food and Drug Administration (FDA), a position he assumed in 2009 along with Deputy Commissioner for Science and Public Health (2009-2012). As FDA's Chief Scientist he had broad responsibility for strategic leadership of crosscutting scientific and public health efforts, including developing and implementing FDA's Strategic Plan for Regulatory Science and FDA's public health preparedness and response and medical countermeasures efforts.A graduate of Harvard, Dr. Goodman received his M.D. from the Albert Einstein College of Medicine and did residency and fellowship training in Medicine, Infectious Diseases and Oncology at the Hospital of the University of Pennsylvania and at the University of California in Los Angeles (UCLA), where he was also Chief Medical Resident. https:/natureandsciencepodcast.com
This isn't exactly the radical message one would expect from a primary physician from Columbia, Maryland. But according to Dr Andy Lazris, co-author of A Return to Healing, Big Pharma wields an iron grip on the American healthcare system. And it's only by aggressively challenging the control of the pharmaceutical industry, Lazris says, that we can begin to reform the system. Lazris discusses how pharmaceutical companies heavily influence healthcare through funding medical organizations, research, and federal agencies like the CDC and FDA. He advocates for a return to patient-centered medicine with longer appointment times and less emphasis on unnecessary tests and medications. He suggests three core reforms: removing pharmaceutical influence from federal agencies, changing Medicare reimbursement to favor primary care over procedures, and increasing Medicare funding for primary care residency programs. Interestingly, Lazris views RFK Jr.'s health agency cuts as chaotic, but potentially beneficial.Five Key Takeaways from Andy Lazris's Interview* Pharmaceutical Industry Influence: The pharmaceutical industry has excessive influence over healthcare, including federal agencies (CDC, FDA), medical associations, academic research, and treatment protocols, prioritizing profit over patient wellbeing.* Primary Care Crisis: Primary care physicians are a "dying breed" despite their importance, as they face burnout from administrative burdens, quality metrics, protocol constraints, and insufficient time with patients.* Protocol-Driven Medicine: Doctors are increasingly forced to follow standardized protocols and quality indicators rather than providing individualized care, with financial penalties for not adhering to these guidelines.* Patient-Centered Reform: Lazris advocates for a return to healing through longer patient visits (40 minutes), focusing on lifestyle factors like diet and exercise (duh), and reducing unnecessary testing and medication.* Actionable Reforms: Lazris proposes three immediate reforms: eliminating pharmaceutical influence in federal agencies, restructuring Medicare reimbursement to favor primary care over procedures, and increasing Medicare funding for primary care residency programs.Dr. Andy Lazris is a physician Board Certified in Internal Medicine. He has practiced both primary care Internal Medicine and Geriatrics for the past 30 years. In addition to Internal Medicine board certification, he has a Certified Medical Director (CMD) degree and is the director of several long term care facilities in Howard County and beyond. He also is a certified wound specialist physician with a CWSP degree. Dr. Lazris is a Magna Cum Laude and Phi Beta Kappa graduate of Brown University. He received a full merit scholarship to Albert Einstein College of Medicine in New York and completed his Internal Medicine training at University of Virginia Hospital. In 2021 and 2022 Dr. Lazris received the prestigious Top-Doc recognition in Geriatrics for the Baltimore region. In 2022 he was named one of America's most honored doctors. He has received numerous accolades and awards for his practice of medicine, his writing, and his work to reform health care.Named as one of the "100 most connected men" by GQ magazine, Andrew Keen is amongst the world's best known broadcasters and commentators. In addition to presenting the daily KEEN ON show, he is the host of the long-running How To Fix Democracy interview series. He is also the author of four prescient books about digital technology: CULT OF THE AMATEUR, DIGITAL VERTIGO, THE INTERNET IS NOT THE ANSWER and HOW TO FIX THE FUTURE. Andrew lives in San Francisco, is married to Cassandra Knight, Google's VP of Litigation & Discovery, and has two grown children.Keen On America is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit keenon.substack.com/subscribe
In this Healthy, Wealthy, and Smart Podcast episode, host Dr. Karen Litzy welcomes Dr. Nicole Fleischman, a board-certified urogynecologist based in New York. Dr. Fleischman specializes in treating women with pelvic floor conditions, including urinary incontinence and organ prolapse, utilizing both medical and surgical approaches. During the conversation, they explore a paradigm shift in understanding pelvic health—moving away from the traditional view of pelvic weakness and the need for strengthening to a more nuanced perspective. Dr. Fleischman also discusses her book, "The Second Mouth," which delves into these concepts. Tune in to gain insights into women's urinary health and the importance of specialized care in this field. Time Stamps: [00:01:26] Urogynecology and pelvic health. [00:04:32] Pelvic floor muscle understanding. [00:08:12] Pelvic floor awareness through breathing. [00:12:19] Stomach sucking and breathing issues. [00:14:14] Breathing and pelvic floor health. [00:18:45] Pelvic floor awareness and coordination. [00:21:51] Surgery necessity in urogynecology. [00:26:21] Empowering women through education. [00:29:10] Biopsychosocial lens in medicine. [00:32:19] Importance of proper toilet training. [00:34:55] Incontinence awareness and prevention. [00:38:26] Breathing techniques for health. [00:42:07] Knowledge sharing in healthcare. More About Dr. Nicole Fleischman: Dr. Fleischmann is board certified in urology and Female Pelvic Medicine and Reconstructive Surgery. She received her medical degree from the State University of New York Downstate Health Sciences University in Brooklyn, NY, where she graduated summa cum laude. Dr. Fleischmann completed her surgery and urology residency at Albert Einstein College of Medicine in Bronx, NY and continued her training in a fellowship at NYU School of Medicine. She is passionate about practicing an integrative approach to urogynecology, correcting the pervasive, unconscious and paradoxical behaviors which can turn into the structural problems and bothersome symptoms that prompt women to seek care. She is the author of the new book “The Second Mouth”, which addresses the powerful mind-body connection in functional urology. Dr. Fleischmann serves as Director of FPMRS at White Plains Hospital Center where she has been in clinical practice for the last 25 years. She holds an active appointment as Assistant Clinical Professor in Obstetrics and Assistant Clinical Professor of Gynecology and Urology at Albert Einstein College of Medicine. Additionally, she is a member of the American Urologic Association and Society for Urodynamics and Female Urology (SUFU). Dr. Fleischmann is the author of several research publications and presentations. She lives and practices in New York.Resources from this Episode: The Second Mouth Book Dr. Fleischman on TikTok Dr. Fleischmann on Instagram Jane Sponsorship Information: Book a one-on-one demo here Front Desk @ Jane Mention the code LITZY1MO for a free month Follow Dr. Karen Litzy on Social Media: Karen's Twitter Karen's Instagram Karen's LinkedIn Subscribe to Healthy, Wealthy & Smart: YouTube Website Apple Podcast Spotify SoundCloud Stitcher iHeart Radio
Follow the intellectual and emotional journey of a group of medical students at Albert Einstein College of Medicine in the Bronx in the new PBS documentary "The Calling: A Medical School Journey". Captured through verité scenes and personal video diaries, the film offers an inside look at America's healthcare system through the eyes of these aspiring practitioners as they learn what it takes to become a doctor in one of the country's most underserved communities. On this episode I speak with the filmmaker Asako Gladsjo and one of the medical students from her documentary, Shauna Phinazee. The film premieres on PBS Monday, March 17th. https://youtu.be/8tMGWx-8PIY From the DC/DOX film festival website: Asako Gladsjo is an award-winning documentary director, producer, and writer based in New York City. Her recent credits include the upcoming "Eyes on the Prize III" for HBO; "Rise and Rebuild: A Tale of Three Cities"; "Why We Hate" for Discovery; "(Un)Well" for Netflix; "By Whatever Means Necessary", for Epix; the PBS special "Black America Since MLK: And Still I Rise"; Soundtracks: "Songs that Made History" for CNN; and "The African Americans: Many Rivers to Cross", which won Emmy, DuPont, Peabody, and NAACP Image awards. She has directed and written documentaries on society, culture, race, and immigration for international broadcasters including Arte, BBC, and France Télévision. She teaches directing in the School of Visual Art's MFA Program in Social Documentary.
What if doctors led the next wave of healthcare innovation? Join us for an eye-opening conversation with Dr. Manju Dawkins, board-certified dermatologist and co-founder of Thimble Health—the first comprehensive solution for alleviating needle pain and stress. She'll share why physicians should get involved in startups, how innovation can transform patient care, and why compassion is key to healthcare advancements.Dr. Dawkins earned her B.A. from Columbia University and her M.D. from the University of Maryland. She completed her dermatology residency and served as Chief Resident at Albert Einstein College of Medicine in the Bronx, NY. As an Assistant Professor at Mount Sinai School of Medicine, she was twice named Teacher of the Year. With experience in academic, private, hospital-based, and group practice settings in New York and Los Angeles, she brings a wealth of knowledge to the conversation.Fun fact: She is 5'2" (on a good day). Dr. Dawkins played Division I basketball at Columbia University and served as team captain her senior year. She is a founding and current member of the Columbia Women's Basketball Advisory Board and a member of the Columbia Athletics Women's Leadership Council.Don't miss this inspiring discussion on how physicians can drive meaningful change in healthcare!Website: thimblehealth.comInstagram:@thimble.healthManju's LinkedIn https://www.linkedin.com/in/manju-dawkins-md-a0224359/Thimble's LinkedIn https://www.linkedin.com/company/thimblehealth/Tik Tok: https://www.tiktok.com/@thimble.health
Dr. Armin Feldman's Pretrial Prelitigation Medical Legal Consulting Coaching Program will teach you to build your own nonclinical consulting business as a valued consultant to attorneys without doing med mal cases or expert witness work. Armin will teach you everything from business concepts to the medicine involved when launching your new consulting business during one year of unlimited coaching. For more information go to nonclinicalphysicians.com/mlconsulting/ Learn the business and management skills you need by enrolling in the University of Tennessee Physician Executive MBA program at nonclinicalphysicians.com/physicianmba. Get the FREE GUIDE to 10 Nonclinical Careers at nonclinicalphysicians.com/freeguide. Get a list of 70 nontraditional jobs at nonclinicalphysicians.com/70jobs. =============== Robert J. Cooper, MD, is an attending physician in the Department of Endocrinology at Holyoke Medical Center in Holyoke, Massachusetts. He received his medical degree from Albert Einstein College of Medicine, Bronx, New York, and completed residency training in internal medicine at Long Island Jewish Hospital, New Hyde Park, New York. He completed fellowship training in endocrinology at Long Island Jewish Hospital and Winthrop–University Hospital, Mineola, New York. He lectured this past year at SEAK on combating physician burnout with nonclinical diversification, including knowledge consulting. He provides keynote lectures and/or provide workshops to physician groups interested in combining nonclinical and clinical activities. During these lectures, he provides a roadmap for entrance to nonclinical work while maintaining a flexible clinical presence. In this week's interview, Robert explains how and why he started adding nonclinical part-time work to his career, as he cut back on his clinical time. John and Robert discuss several types of knowledge consulting, including expert witness consulting. And Robert provides advice for those physicians who want to pursue these opportunities, including how to optimize earnings, and how to please the organizations looking for your assistance. You'll find links mentioned in the episode at nonclinicalphysicians.com/part-time-consulting/
Gut, Food, & Health series “Your body will tell you what it needs. Be curious about what your body's telling you, you will make the right decision.” —Dr. Edison de Mello The health of our gut is intricately tied to the health of our mind. Emerging research reveals just how profoundly our thought patterns can influence digestive function and overall well-being. Hence, mastering the mind-gut connection may be the key to unlocking optimal vitality. Dr. Edison de Mello is a pioneering integrative medicine expert and clinical psychotherapist. As the Founder and Chief Medical Officer of the Akasha Center for Integrative Medicine, he blends cutting-edge science with holistic wisdom to help patients achieve transformative results. Tune in as Dr. de Mello shares eye-opening insights on the surprising link between our thoughts, gut function, and mental resilience. Meet Dr. de Mello: Dr. Edison de Mello, MD, PhD is the founder and Chief Medical Officer of the Akasha Center for Integrative Medicine. He is a board-certified integrative physician and a licensed psychotherapist. Dr. de Mello completed his residency at the Albert Einstein College of Medicine at Beth Israel Medical Center in New York City, where he trained in a biopsychosocial model and integrated complementary medicine into Family Medicine. Inspired by his grandmother, Nana, who practiced natural healing, Dr. de Mello's approach combines Western and Eastern medicine, focusing on treating the mind, body, and spirit. He has written several articles and contributed to Dr. Andrew Weil's upcoming book on the microbiome and food addiction. Dr. de Mello is also on the advisory board of several organizations and a member of various professional associations. Website Instagram Facebook YouTube X Connect with NextGen Purpose: Website Facebook Instagram LinkedIn YouTube Resources:
Gut, Food, & Health series “The food that you eat affects everything, including your mental health.” —Dr. Edison de Mello What if the key to better mental health was as simple as the food on your plate? Emerging research reveals the profound influence of gut health on cognitive function, mood, and emotional resilience. By nourishing the body, we may unlock the path to nourishing the mind. Dr. Edison de Mello is an integrative medicine specialist and the founder of the Akasha Center for Integrative Medicine. As a physician and psychologist, he has dedicated his career to exploring the intricate connections between physical, mental, and emotional well-being. Tune in as Dr. de Mello shares his insights on leveraging the power of nutrition to support brain health, combat depression, and optimize cognitive performance. Meet Dr. de Mello: Dr. Edison de Mello, MD, PhD is the founder and Chief Medical Officer of the Akasha Center for Integrative Medicine. He is a board-certified integrative physician and a licensed psychotherapist. Dr. de Mello completed his residency at the Albert Einstein College of Medicine at Beth Israel Medical Center in New York City, where he trained in a biopsychosocial model and integrated complementary medicine into Family Medicine. Inspired by his grandmother, Nana, who practiced natural healing, Dr. de Mello's approach combines Western and Eastern medicine, focusing on treating the mind, body, and spirit. He has written several articles and contributed to Dr. Andrew Weil's upcoming book on the microbiome and food addiction. Dr. de Mello is also on the advisory board of several organizations and a member of various professional associations. Website Instagram Facebook YouTube X Connect with NextGen Purpose: Website Facebook Instagram LinkedIn YouTube Episode Highlights: 02:16 the Impact of Diet on Mental Health 05:35 Dietary Reboot 08:46 How IV Therapy Works 14:22 Addressing Memory Issues and Depression 19:53 Gut and Mental Health Connection
Gut, Food, & Health series Episode Description: “Your taste buds have a different agenda than your mind and your gut. They're not connected in congruence all the time. So what tastes good in your mouth, is not necessarily what your gut or your brain needs.” —Dr. Edison de Mello Your gut is the gateway to your overall health and well-being. Did you know that the gut-brain connection can significantly influence your mood, cognitive function, and immune system? Maintaining a balanced gut microbiome is crucial for optimizing both physical and mental wellness. Dr. Edison de Mello MD, PhD, is a renowned expert in the field of integrative medicine. As the Founder and Chief Medical Officer of the Akasha Center for Integrative Medicine, he seamlessly blends cutting-edge Western medical practices with the wisdom of Eastern holistic approaches to provide personalized, comprehensive care to his patients. Discover the profound impact of food on gut health, the challenges of implementing dietary changes, and the importance of tailored solutions as Dr. de Mello and Justine Reichman dive deep into the gut health revolution. Meet Dr. de Mello: Dr. Edison de Mello, MD, PhD is the founder and Chief Medical Officer of the Akasha Center for Integrative Medicine. He is a board-certified integrative physician and a licensed psychotherapist. Dr. de Mello completed his residency at the Albert Einstein College of Medicine at Beth Israel Medical Center in New York City, where he trained in a biopsychosocial model and integrated complementary medicine into Family Medicine. Inspired by his grandmother, Nana, who practiced natural healing, Dr. de Mello's approach combines Western and Eastern medicine, focusing on treating the mind, body, and spirit. He has written several articles and contributed to Dr. Andrew Weil's upcoming book on the microbiome and food addiction. Dr. de Mello is also on the advisory board of several organizations and a member of various professional associations. Website Instagram Facebook YouTube X Connect with NextGen Purpose: Website Facebook Instagram LinkedIn YouTube Episode Highlights: 01:13 Food and Gut Health 04:46 Mindfulness and Food Insensitivity 07:33 Allergy and Intolerance Test 13:59 Tailoring Dietary Advice and Personal Needs 16:45 The Role of Medical Education in Nutrition 20:50 Navigating Global Health
Send us a textKetamine is emerging as one of the new break through medical treatments for a variety of ailment from Depression and Anxiety to Post Traumatic Stress. On this episode we feature two board certified doctors who administer these treatment and are here to bear witness to the benefits.Dr. Joseph Affortunato:Joseph Affortunato, DO, is a board-certified Emergency Medicine physician who co-founded KetaRevive. Dr. Affortunato is devoted to providing exceptional care to all his patients in Bergen and Morris counties, as well as the surrounding areas in northern New Jersey.Dr. Affortunato is ready to use his experience and expertise to treat patients with chronic pain and mental health disorders with this new and exciting treatment of ketamine infusion.Dr. Jerome Balbin:Jerome Balbin, MD, FAAEM is one of the co-founders of KetaRevive. He is a board-certified emergency medicine physician who is passionate about providing exceptional patient care. He is known nationally and internationally as a result of his impact in the medical field with numerous journal publications and leadership roles in his specialty. He is currently an active lecturer for numerous medical and educational organizations. Dr. Balbin completed his undergraduate studies at The College of New Jersey before pursuing his medical degree at Rutgers University - Robert Wood Johnson Medical School. Dr. Balbin went on to complete his residency at Albert Einstein College of Medicine - Montefiore/Jacobi Medical Center in the Bronx. Recognizing the importance of improving patient care through education, he then pursued a fellowship in Medical Education & Simulation at New York City Health+Hospitals Simulation Center.Dr. Balbin's commitment to his patients is evident in his compassionate and caring approach. He firmly believes in building strong doctor-patient relationships and understanding the unique goals and aspirations of each person under his care. Dr. Balbin is a compassionate healthcare professional who prioritizes patient care above all else especially when taking care of patients at KetaRevive during their ketamine treatments.KetaRevive WebsiteFind The Suffering PodcastThe Suffering Podcast InstagramKevin Donaldson InstagramMike Failace InstagramApple PodcastSpotifyYouTubeThe Suffering Podcast FamilySherri AllsupKetaReviveToyota of HackensackPoPl Discount code TSP20Support the showThe Suffering Podcast Instagram Kevin Donaldson Instagram TikTok YouTube
A common worry among older adults is how their brains and bodies might decline as they age.A small but fortunate group will live past their 95th birthdays, while staying cognitively sharp and free of major health complications. They're called “SuperAgers.”Researchers are working to figure out some of the genetic factors behind SuperAgers' longevity—and how that knowledge might help the rest of the population live longer and healthier lives.Ira talks with Dr. Sofiya Milman, director of Human Longevity Studies at Albert Einstein College of Medicine and the lead researcher of the SuperAgers Family Study; and one of the study's participants, Sally Froelich, a 95-year-old New York resident.Transcript for this segment will be available after the show airs on sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.