Podcasts about HIV

Human retrovirus, cause of AIDS

  • 11,353PODCASTS
  • 25,430EPISODES
  • 43mAVG DURATION
  • 4DAILY NEW EPISODES
  • Nov 10, 2025LATEST
HIV

POPULARITY

20172018201920202021202220232024

Categories




    Best podcasts about HIV

    Show all podcasts related to hiv

    Latest podcast episodes about HIV

    Predators I've Caught With Chris Hansen
    “I'm lonely. I'm a lonely person.”- Matthew Klein

    Predators I've Caught With Chris Hansen

    Play Episode Listen Later Nov 10, 2025 46:16


    Chris delves into the case of Matthew Klein, a 43-year-old caught attempting to meet underage boys online. Using his expertise, Chris explores the troubling excuses predators, like Klein, give, such as loneliness and personal struggles. The episode uncovers Klein's dual life as a law firm receptionist and Uber driver, questioning his motivations and the potential harm he posed. Chris also discusses legal charges, including Klein's failure to disclose HIV status, and reflects on the influences behind his crime-fighting career. The episode concludes with audience interactions and Hansen's personal anecdotes.  Sponsored by:  TruthFinder.com. To get the answers you're looking for about the new people in your life, and to discover information on potential predators, go to www.TruthFinder.com/predators Home Title Lock: Go tohttps://hometitlelock.com/chrishansen and use promo code HANSEN to get a FREE title history report and a FREE TRIAL of their Triple Lock Protection! For details visit https://hometitlelock.com/warranty   Go to https://expressvpn.com/CHRISHANSEN and find out how you can get up to 4 extra months thanks to our sponsor, ExpressVPN! Dupe: Go to Dupe.com today and make your holiday shopping so much easier. It's 100% free to use. Stop overspending on gifts and start saving big this holiday season with Dupe.com Get your official Chris Hansen merchandise at https://haveaseat.dashery.com/ Learn more about your ad choices. Visit megaphone.fm/adchoices

    Cinema Smorgasbord
    Episode 289 – How Do You Do, Fellow Kids? – Parting Glances (1986)

    Cinema Smorgasbord

    Play Episode Listen Later Nov 10, 2025 71:01


    On a returning HOW DO YOU DO, FELLOW KIDS? (the world's finest Steve Buscemi-themed podcast) we're heading back to the past with Bill Sherwood's gay romantic drama PARTING GLANCES from 1986, featuring Steve Buscemi's breakout performance as Nick, an HIV-positive rock musician. Two straight dudes talking about a pioneering queer work? It happened! Now you can hear it and all the latest Steve Buscemi news. Enjoy! The post Episode 289 – How Do You Do, Fellow Kids? – Parting Glances (1986) first appeared on Cinema Smorgasbord.

    Above The Noise
    Dr. Agnella (Aggy) Chingwaro: Fighting HIV With Faith And Medicine

    Above The Noise

    Play Episode Listen Later Nov 8, 2025 62:17 Transcription Available


    Send us a Text Message about the podcastA five-day trek, a river that swallows missteps, and a video call that saves a mother and baby—this is what frontline HIV care looks like in Papua, Indonesia. We sit down with Dr. Agnela “Iggy” Chingwaro, an infectious disease physician from Zimbabwe, whose work braids medical expertise with faith, cultural humility, and stubborn hope. Her story exposes the hard truths behind late testing, the fear of national registration, and the maze of more than 300 local languages that shape how people understand illness, trust, and treatment.We unpack the crucial difference between HIV and AIDS, why “undetectable” means suppressed rather than cured, and how that nuance can make or break adherence. Dr. Iggy contrasts Africa's evolving HIV response with Papua's current challenges, where stigma keeps many away until opportunistic infections like TB and meningitis take hold. She details how government-supplied antiretrovirals, TB, and leprosy drugs still need community bridges—portable diagnostics, trained local educators, and clinics willing to meet people where they are. You'll hear how her team trains traditional midwives to screen pregnant women, uses telemedicine to coach emergency care, and partners with pilots and pastors to reach mountainside villages.The conversation turns deeply human: the adoption of a child orphaned by AIDS, the refusal of ambulance drivers to transport patients due to fear, and the practical ways to dismantle myths about transmission. We also shine a light on the “forgotten generation”—youth facing rising HIV rates alongside alcohol and drug abuse—and the vision for a safe, youth-friendly center that offers counseling, education, and dignity. This is global health at eye level: compassionate, persistent, and built on trust.If this moved you, help us grow the impact: subscribe, leave a rating, and share with a friend. Got thoughts or want to support Dr. Aggy's work? Email abovethenoise24@gmail.com and join the conversation.#HIV;  #AIDS;   #Papua  # Indonesia Leave reviewFollow and ShareSend Text Message New WebsiteBuy Me A Coffee Support the show#abovethenoise24# faith#reconciliation#race#racialreconciliationWe appreciate your support: Buy Me A CoffeeStay in touch: Email us at: abovethenoise24@gmail.com Facebook: @abovethenoise24 Instagram: abovethenoise24 Podcast art by Mario Christie.

    HIV Hour
    148: HIV Hour 16th October 2025

    HIV Hour

    Play Episode Listen Later Nov 8, 2025 46:26


    On the show The 2nd part of Davids Interview with Ann Whatmore, talking about her experiences has a an HIV nurse in the 1980s and 90s in Brighton. A in-depth chat with Jordan Chan. Jordan's work as an LGBTQ+ activist and fundraiser, as well as the inspiration behind The Red Ribbon 2026 Calendar. A reminder you can order your calendar now at https://payhip.com/b/M5bjs . Follow Jordan on Instagram. .https://www.instagram.com/jordanwch_92/ HIV News and Great music too!

    VOV - Sự kiện và Bàn luận
    Tiêu điểm - Trẻ em dưới 15 tuổi nhiễm HIV: Nỗi đau âm thầm

    VOV - Sự kiện và Bàn luận

    Play Episode Listen Later Nov 7, 2025 7:08


    VOV1 - Nhiễm HIV qua đường tình dục ở tuổi vị thành niên là một nỗi đau âm thầm và dai dẳng. Đáng tiếc là những năm gần đây, ngày càng nhiều bạn trẻ phải đối mặt với cú sốc này.

    Sniffies' Cruising Confessions
    Fisting For Compliments

    Sniffies' Cruising Confessions

    Play Episode Listen Later Nov 6, 2025 48:01 Transcription Available


    Fisting used to be a niche fetish practiced by kinksters in dungeons, but today “Fisting is the It Girl” according to writer and expert fister Alexander Cheves. In this deep dive, Alex explains how the availability of fisting content on Twitter has led to a surge of interest from younger queer folks in recent years. But there’s a lot that first time fist fuckers need to know about how to prepare and train for play, in order to avoid serious injuries. Luckily, Alex has plenty of smart tips (and sweet stories) to share for both beginners and pros. Get the x-lube and puppy pads ready. It’s time to go Fisting For Compliments. Follow Sniffies' Cruising Confessions: cruisingconfessions.com Try Sniffies: sniffies.com Follow Sniffies on Social: Instagram: instagram.com/sniffiesapp X: x.com/sniffiesapp TikTik: tiktok.com/@sniffiesapp Follow the hosts: Gabe Gonzalez: instagram.com/gaybonez Chris Patterson-Rosso: instagram.com/cprgivesyoulife Guests featured in this episode: Alex Cheves: instagram.com/badalexcheves/See omnystudio.com/listener for privacy information.

    EquiTEA
    Unspoken Truths: HIV Awareness in the Latinx Community

    EquiTEA

    Play Episode Listen Later Nov 6, 2025 21:19


    On this episode of EquiTEA, Juan sits down with Dr. Carlos Calderon, Medical Director of the HIV/STD Early Intervention Program at Riverside University Health System- Public Health, for a powerful conversation in honor of National Latinx HIV & AIDS Awareness Day, observed Oct. 15. Together, they unpack the disproportionate impact of HIV on Hispanic/Latinx communities, spotlight the life-saving importance of testing and early detection and confront the stigma that continues to surround the virus. Resources: To get connected with HIV/STD resources, please visit: ⁠https://ruhealth.org/public-health/rivco-hiv-std-program

    Keeping Current
    The Hidden Battle: Understanding Chronic Inflammation in Aging People Living With HIV and Comorbidities

    Keeping Current

    Play Episode Listen Later Nov 6, 2025 35:11


    Untangle the hidden links between chronic inflammation, aging, HIV, and comorbidities. Credit available for this activity expires: 11/5/26 Earn Credit / Learning Objectives & Disclosures: https://www.medscape.org/viewarticle/1003078?ecd=bdc_podcast_libsyn_mscpedu

    The Best of Breakfast with Bongani Bingwa
    US aid cuts threaten to derail SA's HIV fight

    The Best of Breakfast with Bongani Bingwa

    Play Episode Listen Later Nov 6, 2025 9:30 Transcription Available


    Bongani Bingwa speaks to a health expert as South Africa faces a major setback in its decades-long fight against HIV. After years of progress marked by fewer deaths, wider treatment access, and millions on life-saving medication, the sudden withdrawal of key U.S. funding since February has left clinics struggling to stay open. The impact is already being felt — with an estimated 660,000 viral-load tests missed, thousands may be going without critical monitoring to ensure their treatment is effective. This morning, we unpack what these aid cuts mean for the country’s public health system, the vulnerable communities most at risk, and the urgent steps needed to prevent South Africa from losing hard-won ground in the battle against HIV. 702 Breakfast with Bongani Bingwa is broadcast on 702, a Johannesburg based talk radio station. Bongani makes sense of the news, interviews the key newsmakers of the day, and holds those in power to account on your behalf. The team bring you all you need to know to start your day Thank you for listening to a podcast from 702 Breakfast with Bongani Bingwa Listen live on Primedia+ weekdays from 06:00 and 09:00 (SA Time) to Breakfast with Bongani Bingwa broadcast on 702: https://buff.ly/gk3y0Kj For more from the show go to https://buff.ly/36edSLV or find all the catch-up podcasts here https://buff.ly/zEcM35T Subscribe to the 702 Daily and Weekly Newsletters https://buff.ly/v5mfetc Follow us on social media: 702 on Facebook: https://www.facebook.com/TalkRadio702 702 on TikTok: https://www.tiktok.com/@talkradio702 702 on Instagram: https://www.instagram.com/talkradio702/ 702 on X: https://x.com/Radio702 702 on YouTube: https://www.youtube.com/@radio702See omnystudio.com/listener for privacy information.

    Strawberry Letter
    Health Tips: She discusses social determinants of health; education, food deserts, and redlining which contribute to disparities.

    Strawberry Letter

    Play Episode Listen Later Nov 5, 2025 39:53 Transcription Available


    Tank Talks
    Building a Billion-Dollar Biotech Legacy with Roberto Bellini of BSQUARED Capital

    Tank Talks

    Play Episode Listen Later Nov 5, 2025 48:50


    In this episode of Tank Talks, host Matt Cohen sits down with Roberto Bellini, Co-Founder of BSQUARED Capital and former CEO of Bellus Health, for a powerful conversation about family, legacy, and resilience in the world of biotech.Originally recorded just two weeks before the passing of his father, Dr. Francesco Bellini, one of the founding giants of Canadian biotech, this re-recorded episode serves as a moving tribute to the man known as “Mr. Biotech Canada.” Roberto opens up about what it was like growing up under the guidance of such a visionary figure and how that experience shaped his own path as an entrepreneur and leader.He reflects on the highs and lows of leading Bellus Health, from moments of near collapse to its remarkable $2 billion acquisition by GSK, sharing lessons on risk-taking, perseverance, and the importance of staying grounded through uncertainty. Roberto also offers his perspective on the future of Canadian biotech, highlighting the need for stronger late-stage funding and how BSquared Capital is helping to cultivate the next generation of innovators.This episode isn't just about business success; it's about honoring a legacy, learning through adversity, and discovering what it truly means to build something that endures.The Legacy of Dr. Francesco Bellini (00:02:52)* Francesco Bellini's incredible immigrant story: from arriving in Canada with nothing to a $6B biotech exit.* Business was the family's dinner table conversation, and attending AGMs as a child.* The founding of Biochem Pharma and the discovery of the groundbreaking HIV treatment.* “He was a visionary... he saw things before other people saw them.”Growing Up in Biotech (00:06:30)* Roberto's early memories of board meetings and dinner-table business lessons* How being “in the room” shaped his entrepreneurial mindset* Watching a $6B biotech deal become part of family historyThe Rise, Fall, and Rebirth of Bellus Health (00:08:27)* Roberto's journey from family office analyst to a 30-year-old, first-time CEO of a public company.* The devastating failure of the phase three trial for a rare kidney disease.* Inside a Biotech Failure: The intense, weekend-long “war room” process of unblinding clinical trial data and preparing for a public announcement.The Second Act: Finding the Cough Drug (00:13:47)* Discovering a promising molecule through the NeoMed Institute* Betting the company's future on a last-chance asset* Raising $20M when no one believed and turning it into a $2B successNegotiating the GSK Deal (00:24:45)* The strategic shift from “build-to-sell” to “build-to-scale”, positioning the company for a premium acquisition.* The M&A Playbook: Why you should never lead with a desire to sell; the importance of building for independence.* The high-stakes negotiation with GSK: going from an $11 offer to $14.75, almost losing the deal, and the “mellow tone” that saved it.* The entrepreneur's dilemma: “Every single entrepreneur I've met that sold their company, there's always a moment of not wanting to do it.”Building Canada's Biotech Future (00:30:11)* Why Canada has the innovation but lacks the enduring biotech giants.* The critical gap: The need for more late-stage capital and the role of Canadian pension funds.* The “Gilead of the North” vision: Creating a virtuous cycle of capital, entrepreneurs, and translational science.* Upcoming trends: The convergence of AI and drug discovery to de-risk development and lower costs.Beyond the Lab: Leadership, Risk, and Legacy (00:46:20)* Learning to embrace risk and find joy in reinvention* The best advice from Dr. B: “Spend your money, it'll make you want to earn more.”* Why true success isn't just building a company, but building peopleAbout Roberto BelliniFounder & Managing Partner, BSQUARED CapitalRoberto Bellini is a second-generation biotech entrepreneur and investor. As the former CEO of Bellus Health, he led the company's dramatic turnaround and eventual $2 billion acquisition by GSK. Drawing on his deep operational experience in drug development, he now co-manages BSQUARED Capital, a family office focused on investing in and supporting promising biotech ventures. He is a passionate advocate for building a stronger, more resilient biotech ecosystem in Canada.Connect with Roberto Bellini on LinkedIn: https://www.linkedin.com/in/robertobellini/Visit BSQUARED Capital Website: https://bsq-c.com/Connect with Matt Cohen on LinkedIn: https://ca.linkedin.com/in/matt-cohen1Visit the Ripple Ventures website: https://www.rippleventures.com/ This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit tanktalks.substack.com

    The Dr. Haley Show
    127 | Why You Crave Junk Food Instead of Being Addicted To Wellness with Ashley James

    The Dr. Haley Show

    Play Episode Listen Later Nov 4, 2025 55:16


    Ashley James is a Master Practitioner and Trainer in Neuro-Linguistic Programming (NLP), Time Line Therapy, and holistic health coaching. She is host of the "Learn True Health" podcast.. She recently published "Addicted to Wellness", a book that guides you through a 12 week program promising a "total metamorphosis" in your approach to health.RESOURCES:This episode's Blog Page:https://drhaley.com/addicted-to-wellness/Buy "Addicted to Wellness" on Amazon:https://amzn.to/4oh1AMKVisit Ashley James's website :Learn True Health"https://learntruehealth.com/TIMESTAMPS:00:00 Intro Snip00:57 Introduce Ashley James02:40 Ashley's previous health challenges and how she overcame them06:48 Dr. Haley tells how he realized Diet Coke was causing tinnitis07:53 Ashley shares her soda healthy replacements09:20 Dr. Haley discusses the difference between medical care and alternative medicine10:40 Ashley discusses the parts of the Blood Type O diet that she likes11:27 Ashley James talks about her whole food plant based cooking program and gives some plant based diet tips13:45 Ashley explains how flu season is a lie and how is it actually candy (sugar) season15:28 Ashley did well from 6 years old until 13 when she rebelled by eating candy. What followed...19:20 Dr. Haley and Ashley James discuss the different diets and why diet dogma is bad22:07 Why you should ease into a big diet change and use the "crowding out" method23:00 Dr. Haley and Ashley discuss why plant foods are becoming more important in our diets24:20 Why do we need to detoxify and eat more fiber27:00 Why you should chew your food more29:32 What are post-biotics?32:54 What is the Food Mood Poop journal?36:20 What is the book "Addicted To Wellness"41:35 What really happens when you are dehydrated?44:45 What is the hydration challenge?48:40 How to get a free call with Ashley James49:30 What you get on the "Learn True Health Podcast"51:00 What do we know about aloe vera and HIV?53:20 How to Turn Off Anxiety

    Going anti-Viral
    Medical Cannabis: Evidence and Insight with Dr Donald Abrams

    Going anti-Viral

    Play Episode Listen Later Nov 4, 2025 29:34


    In episode 60 of Going anti-Viral, Dr Donald Abrams joins host Dr Michael Saag to discuss medical cannabis. Dr Abrams is a professor emeritus at the University of California San Francisco and a specialist in integrative oncology at the Osher Center for Integrative Health. Dr Abrams has studied complementary and alternative therapies, including mind-body treatments, botanical therapies, medical use of cannabis and herbal therapies used in traditional Chinese medicine. He continues to research the health effects of medical cannabis. Dr Abrams was previously at the forefront in HIV/AIDS research and treatment at San Francisco General Hospital and served as chief of the medical oncology service from 2003 to 2017. Dr Saag and Dr Abrams discuss the history of medical cannabis and the challenges Dr Abrams experienced in researching its use for medical therapy. They discuss the medical benefits of cannabis and the recommendations that clinicians may make as well as addressing the differences in products available including THC and CBD. They also discuss research in whether use of cannabis in young adults is related to schizophrenia. Finally, Dr Saag and Dr Abrams discuss the future of medical cannabis and whether physicians should continue to provide a role in its use, whether the scheduling of cannabis as a controlled substance will change, and the type of research that is needed to continue to explore where its use is beneficial. 0:00 – Introduction1:20 – Overview of the history of medical cannabis 4:10 – The fight for medical cannabis research and its use in people with AIDS 10:59 – Understanding the medical benefits of cannabis particularly for pain, insomnia, nausea, vomiting, anxiety, and depression 13:15 – How physicians navigate recommendations for the use of cannabis and the differences with the types of cannabis whether inhaled, digested, or tinctures 18:13 – CBD vs. THC: understanding the differences and other possible cannabinoid therapeutics23:25 – The role of physicians in the future of medical cannabis, the need for more research, and the overall availability for people who want it 25:57 – Overview of research if there a relationship between the use of cannabis and schizophrenia in young adults __________________________________________________Produced by IAS-USA, Going anti–Viral is a podcast for clinicians involved in research and care in HIV, its complications, and other viral infections. This podcast is intended as a technical source of information for specialists in this field, but anyone listening will enjoy learning more about the state of modern medicine around viral infections. Going anti-Viral's host is Dr Michael Saag, a physician, prominent HIV researcher at the University of Alabama at Birmingham, and volunteer IAS–USA board member. In most episodes, Dr Saag interviews an expert in infectious diseases or emerging pandemics about their area of specialty and current developments in the field. Other episodes are drawn from the IAS–USA vast catalogue of panel discussions, Dialogues, and other audio from various meetings and conferences. Email podcast@iasusa.org to send feedback, show suggestions, or questions to be answered on a later episode.Follow Going anti-Viral on: Apple Podcasts YouTubeXFacebookInstagram...

    Books and Beyond with Bound
    8.20 Gardiner Harris: On The Dark Secrets of Johnson & Johnson

    Books and Beyond with Bound

    Play Episode Listen Later Nov 4, 2025 55:19 Transcription Available


    What dangerous secrets lie beneath the "comforting newborn smell" of one of the most trusted companies in the world?In this explosive episode, Pulitzer Prize-nominated NYT journalist Gardiner Harris pulls back the curtain on Johnson & Johnson's history, detailed in his book No More Tears: The Dark Secrets of Johnson & Johnson.Gardiner reveals J&J's systemic deception, from knowingly selling asbestos-contaminated baby powder for seven decades to marketing drugs as cancer cures that were actually "Miracle Grow" for tumours. He exposes J&J's hidden role in the opioid crisis and their shocking refusal to share life-saving HIV drugs with Africa, costing millions of lives.Drawing from years of investigative reporting, Gardiner explains how corporate PR, media influence, and medical incentives allow giants like J&J to evade accountability, even with secret Grand Jury testimony as evidence. Tara and Gardiner also discuss the stories that didn't make it into the book and the mental toll of exposing the truth.Tune in for an essential, eye-opening conversation that forces consumers to question the products of a company they love and trust.Upcoming Bound RetreatsImmersive, one-of-a-kind literary experiences that take writers into the heart of India's most breathtaking landscapes.Wiling: A Weekend Writing Retreat | 28-30 November, 2025Learn more: https://boundindia.com/retreats/ Apply to all retreats: http://bit.ly/44TzYpY ‘Books and Beyond with Bound' is the podcast where Tara Khandelwal and Michelle D'costa uncover how their books reflect the realities of our lives and society today. Find out what drives India's finest authors: from personal experiences to jugaad research methods, insecurities to publishing journeys. Created by Bound, a storytelling company that helps you grow through stories. Follow us @boundindia on all social media platforms.

    In conversation with...
    Deborah Persaud on the possibility of HIV remission in neonates

    In conversation with...

    Play Episode Listen Later Nov 4, 2025 35:39


    In the ongoing search for an HIV cure, promising evidence suggests that early treatment of infants might help achieve lasting HIV remission: the IMPAACT P1115 study is designed to investigate that potential. We talk to a lead investigator about what we know so far.Read the full article: www.thelancet.com/journals/lanhiv/article/PIIS2352-3018(25)00189-4/fulltextContinue this conversation on social!Follow us today at...https://thelancet.bsky.social/https://instagram.com/thelancetgrouphttps://facebook.com/thelancetmedicaljournalhttps://linkedIn.com/company/the-lancethttps://youtube.com/thelancettv

    Common Censored
    Episode 287 - Destructive Billionaires & Hurricanes, No Food For You Just Billions For Israel

    Common Censored

    Play Episode Listen Later Nov 3, 2025 62:02


    In the wake of one of the most intense hurricanes on record, Bill Gates wants you to know that climate change is no biggie.  Meanwhile, we might see HIV rates spike 49% in the next five years if planned cuts go ahead. That's roughly 75,000 new cases.  In that same vein, as more than 40 million people lose their food stamps, the money keeps flowing to Israel - that's the type of funding we just can't live without, government shutdown or no!  And of course, Israel is flaunting its untouchable status, violating the ceasefire literally hundreds of times. Gaza is still being decimated, murdered, starved.  And in Sudan, UAE-backed forces commit horrific acts of torture and murder as part of a coalition of US and Israeli interest in Sudan's natural resources.  Because ultimately, when the going gets tough, the empire goes back to its roots, as a dealer of doom.    leecamp.net artkillingapathy.com

    The Sandy Show Podcast
    JB and Sandy Never Get The "Fun" Version of their Wives

    The Sandy Show Podcast

    Play Episode Listen Later Nov 3, 2025 16:52 Transcription Available


     Have you ever wondered how a simple drive could turn into a scene straight out of a movie—complete with flat tires, chaos, and a mysterious ladder in the road? On this episode of The JB and Sandy Show, hosts JB and Sandy McIlree are joined by the ever-adventurous Tricia, who brings tales from Dallas that will leave you laughing, gasping, and itching to tune in. The episode opens with a lively discussion about streaming wars and the impact of the YouTube TV dispute with Disney, ABC, and ESPN—reminding listeners how quickly their favorite shows and games can disappear from their screens. But the real excitement begins when Tricia shares her wild weekend in Dallas, starting with a Romanian food festival (cabbage rolls, skinless sausage, and polenta, anyone?) and ending with a highway disaster that left at least 20 cars stranded with blown tires. Key Moments & Themes:Honky Tonk Festival Announcement: Austin Monthly launches its first annual Honky Tonk Fest, celebrating the city's iconic two-stepping venues like Jenny's Little Longhorn and The Broken Spoke. Tricia's enthusiasm for the festival and her legendary two-stepping partners add a personal touch to the local culture spotlight[1].Highway Mayhem: Tricia recounts a harrowing drive on I-30, where a rogue ladder caused a mass flat tire event. “Within five minutes, all of these cars were taken out on the side of the road. You got here is wrong place, wrong time.” The chaos, quick thinking, and camaraderie among strangers make for a gripping story[1].Romanian Festival Fun: From delicious food to unexpected gymnastics exhibitions and a vampire sighting, Tricia's night out is full of surprises. Her ability to turn any outing into an adventure is on full display.Drag Show Fundraiser: The episode wraps up with Tricia attending a drag show benefit for HIV research, highlighting the vibrant and supportive community spirit that defines Austin and Dallas alike.Memorable Quotes:“Squirming like a worm in hot ashes is what my grandma would say.” – Sandy“Within five minutes, all of these cars were taken out on the side of the road. You got here is wrong place, wrong time.” – Tricia“There's nobody I have two-stepped more with in my life than those two girls. Those two girls will drink the entire festival out of beer.” – Tricia Enjoyed the episode? Subscribe to The JB and Sandy Show, leave a review, and share this episode with friends who love wild stories and local flavor. Your support helps us keep bringing you the best of Austin, Dallas, and beyond!

    Pharma and BioTech Daily
    Precision Oncology and HIV Prevention Breakthroughs

    Pharma and BioTech Daily

    Play Episode Listen Later Nov 3, 2025 7:18


    Good morning from Pharma Daily: the podcast that brings you the most important developments in the pharmaceutical and biotech world. Today, we're diving into a series of fascinating advancements and strategic movements that are shaping the landscape of drug development and patient care.Starting with a significant milestone in precision oncology, China has approved its first EGFR-targeted antibody-drug conjugate. This approval marks a pivotal moment in the industry's shift towards targeted therapies, which promise more precise treatment options with potentially fewer side effects than traditional chemotherapy. Targeted therapies are at the forefront of personalized medicine, where treatments are tailored to individual genetic profiles, offering hope for more effective cancer care.In the realm of HIV prevention, Gilead Sciences has reported impressive sales for its new long-acting pre-exposure prophylaxis medication, Yetztugo. Since its launch in June 2025, Yetztugo has generated $54 million in U.S. sales, underscoring the demand for long-term HIV prevention solutions. This development is part of Gilead's broader strategy to strengthen its HIV franchise as it advances its pipeline with promising candidates like GS-3242 alongside lenacapavir. The aim is to develop treatments that require less frequent dosing, which could significantly improve patient adherence and outcomes. Despite challenges within its HIV portfolio and declining Veklury sales, Gilead Sciences is actively seeking growth opportunities through strategic partnerships and pipeline advancements—an essential approach for navigating patent cliffs while sustaining long-term growth.On the financial front, AbbVie has increased its revenue forecast by $400 million to a staggering $60.9 billion, driven by robust sales from its immunology drugs Skyrizi and Rinvoq. These treatments address chronic inflammatory conditions like psoriasis and rheumatoid arthritis, reflecting AbbVie's strong positioning in this therapeutic area despite competitive pressures. AbbVie continues to report strong earnings from Skyrizi and Rinvoq, reinforcing its dominance in the immunology market and highlighting the profitable nature of successful biologics in treating chronic inflammatory diseases.Biogen continues to bolster its multiple sclerosis franchise by focusing on both legacy treatments and new product launches. This strategy highlights the importance of balancing innovation with lifecycle management to maintain market strength against generic competition—a common challenge in the industry.Meanwhile, the American Academy of Pediatrics has taken a cautious stance by not endorsing leucovorin for autism treatment due to insufficient evidence. This decision emphasizes the critical need for rigorous, evidence-based practices in developing clinical guidelines for complex disorders like autism.Internationally, CSL Seqirus has partnered with Saudi Arabia to supply cell-based influenza vaccines and support local production capabilities. This move aligns with global efforts to enhance pandemic preparedness and healthcare resilience through local manufacturing initiatives.The volatile nature of the biotech sector is evident with reports of 16 companies ceasing operations in 2025 due to high R&D costs and regulatory challenges. Despite these closures, such volatility opens doors for new innovations that could address unmet medical needs.Turning our attention to obesity treatment, Eli Lilly stands at a crucial juncture with its novel obesity medication, orforglipron. The company aims to make this weight loss pill accessible while maintaining financial viability for future R&D—a balancing act faced by many pharmaceutical companies as they strive to deliver affordable yet innovative treatments amid growing global health concerns. However, not all R&D efforts reach fruition. Eli Lilly has decided to discontinue its mid-stage program Support the show

    The Hearing – A Legal Podcast
    EP. 183 – Reforming health laws for better outcomes (Mandeep Dhaliwal, United Nations Development Programme)

    The Hearing – A Legal Podcast

    Play Episode Listen Later Nov 3, 2025 50:52


    Mandeep Dhaliwal, Director of the HIV and Health Group at the United Nations Development Programme (UNDP) joins host Janelle Wrigley to discuss how legal frameworks and governance shape health outcomes worldwide. Drawing on more than 25 years at the intersection of health policy and human rights, Mandeep explains the UNDP's mission and her experiences showing that leadership and participation from affected communities must be at the center of effective public health policy. Mandeep and Janelle explore how punitive laws around HIV drive-up infections, deaths, and costs. They discuss how countries can engage in reform, such as Zimbabwe's repeal of HIV criminalization after a UNDP‑supported legal environment assessment, and they examine access‑to‑medicines barriers tied to patents and trade agreements. Mandeep suggests practical ways communities and legal professionals can advance change in this critical area.

    When Humanitarians Kill
    “No push over”

    When Humanitarians Kill

    Play Episode Listen Later Nov 2, 2025 74:31 Transcription Available


    An interview with Lyn Hatch the mother of Martin, the Aussie kid knowingly provided with tainted blood, who started the legal fight for justice for the Australian victims of the global infected blood scandal.  Support a petition for a Royal Commission of inquiry into the Australian Red Cross/CSL infected blood scandal here https://www.infectedbloodaustralia.com/registrationWatch the speech where former 1980s health minister Neal Blewett claims HIV just ‘fell out of a clear blue sky' https://youtu.be/REv6oC1jYUE?si=mHCs8-bEGIBLfI5iHelp Charles MacKenzie survive by donating to his Go Fund Me here https://gofund.me/4908d7926 The evidence they don't want you to see: https://www.infectedbloodaustralia.com/the-evidence-they-did-t-want-you-to-see

    This Week in Virology
    TWiV 1266: Clinical update with Dr. Daniel Griffin

    This Week in Virology

    Play Episode Listen Later Nov 1, 2025 50:06


    In his weekly clinical update, Dr. Griffin and Vincent Racaniello ponder the nomination of Casey Means for Surgeon General by President Trump, how mRNA vaccines may enhance effectiveness of check point inhibitor cancer therapies, if viral infection associates with cardiac disease, H5N1 isolation from backyard birds and turkey farms, and the effectiveness of the COVID-19, RSV and influenza vaccines before Dr. Griffin deep dives into recent statistics on the measles epidemic, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, if revaccination with the mRNA RSV vaccine is effective, how effective today's COVID-19 vaccine is for protection against severe disease following infection with current viral variants, where to find PEMGARDA, how to access and pay for Paxlovid, can you be retreated with Paxlovid, long COVID treatment center, where to go for answers to your long COVID questions, and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode The Challenge of Malignancies in HIV-1, Beyond Immune Activation and Back to Decreased Immune Surveillance (Journal of AIDS & Clinical Research) SARS-CoV-2 mRNA vaccines sensitize tumours to immune checkpoint blockade (Nature) TWiV 1265: mRNA vaccines make cancer treatment great again (microbeTV: TWiV 1265) Viral Infections and Risk of Cardiovascular Disease (Journal of the American Heart Association) Confirmations of Highly Pathogenic Avian Influenza in Commercial and Backyard Flocks (USDA: Animal and Plant Health Inspection Service) Three large turkey farms in Minnesota hit with H5N1 avian flu (CIDRAP) Updated Evidence for Covid-19, RSV, and Influenza Vaccines for 2025–2026 (NEJM) Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Tracking Measles Cases in the U.S. (Johns Hopkins) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health) Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola)) Presumptive evidence of measles immunity (CDC) Contraindications and precautions to measles vaccination (CDC) Measles vaccine recommendations from NYP (jpg) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses) Weekly surveillance report: Cliff notes (CDC FluView) ACIP Recommendations Summary (CDC: Influenza) Influenza Vaccine Composition for the 2025-2026 U.S. Influenza Season (FDA) RSV: Waste water scan for 11 pathogens (WastewaterSCan) Respiratory Diseases (Yale School of Public Health) US respiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV)) Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP) Safety, Tolerability, and Immunogenicity of Revaccination With mRNA-1345, an mRNA Vaccine Against RSV, Administered 12 Months Following a Primary Dose in Adults Aged ≥50 Years (CID) Vaccine effectiveness of a bivalent respiratory syncytial virus (RSV) pre-F vaccine against RSV-associated hospital admission among adults aged 75–79 years in England (LANCET: Infectious Diseases) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Antigenic and Virological Characteristics of SARS-CoV-2 Variant BA.3.2, XFG, and NB.1.8.1 (bioRxiV) Association of 2024–2025 Covid-19 Vaccine with Covid-19 Outcomes in U.S. Veterans (NEJM) Durability of 2024-2025 COVID-19 Vaccines Against JN.1 Subvariants (JAMA: Internal Medicine) Where to get pemgarda (Pemgarda) EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) Understanding Coverage Options (PAXCESS) Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC) Anticoagulation guidelines (hematology.org) Daniel Griffin's evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Reaching out to US house representative Letters read on TWiV 1266 Dr. Griffin's COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

    RNZ: Tagata o te Moana
    Tagata o Te Moana for 1 November 2025

    RNZ: Tagata o te Moana

    Play Episode Listen Later Nov 1, 2025 30:31


    Coming up in Tagata o te Moana this week: A recent report finds Pacific countries are at risk of becoming "narco-states". Health experts warn Fiji's HIV crisis could spread across the Pacific. And the US government shutdown affects its Pacific territories. All that and more stories from RNZ Pacific.Go to this episode on rnz.co.nz for more details

    3 Things
    Jharkhand HIV infection case, Goa's tourism woes, and Trump-Xi meet

    3 Things

    Play Episode Listen Later Oct 31, 2025 29:58 Transcription Available


    First, we talk to The Indian Express' Shubham Tigga about a case that has emerged in Jharkhand, where five children suffering from Thalassemia went for their regular blood transfusion and came back HIV positive. He talks about the state government's reaction, the hospital's response and the investigation that is happening. Next, we talk to The Indian Express' Pavneet Singh Chadha about the concerns around tourism in Goa. Since a social media controversy broke out last year about Goa's tourism infrastructure, the tourism stakeholders of the state have been concerned about the footfall during its peak tourist season. (13:40)Lastly, we talk about Chinese President Xi Jinping meeting US President Donald Trump on the sidelines of the Asia Pacific Economic Cooperation Summit in South Korea. (26:35)Hosted by Niharika NandaProduced by Niharika Nanda, Ichha Sharma, and Shashank BhargavaEdited and mixed by Suresh Pawar

    Napleiten
    #158: De Groninger HIV-zaak

    Napleiten

    Play Episode Listen Later Oct 31, 2025 40:48


    Tussen 2005 en 2007 raken steeds meer mannen die naar seksfeesten gaan in de Groningse gayscene besmet met het HIV-virus, dat aids kan veroorzaken. Drie mannen die óók op deze feesten te vinden zijn worden ervan verdacht hun slachtoffers op de seksfeesten te drogeren, en ze vervolgens opzettelijk te injecteren met HIV-besmet bloed. Heiko Eckert is inmiddels rechter, maar verdedigde destijds als advocaat een van de drie verdachten. Rechtbank Groningen: https://uitspraken.rechtspraak.nl/details?id=ECLI:NL:RBGRO:2008:BG4169 Hof Leeuwarden: https://uitspraken.rechtspraak.nl/details?id=ECLI:NL:GHLEE:2010:BL0299 Hoge Raad: https://uitspraken.rechtspraak.nl/details?id=ECLI:NL:HR:2012:BT6362 Hof Arnhem: https://uitspraken.rechtspraak.nl/details?id=ECLI:NL:GHARN:2012:BY4618See omnystudio.com/listener for privacy information.

    Sniffies' Cruising Confessions
    Heaux Church

    Sniffies' Cruising Confessions

    Play Episode Listen Later Oct 30, 2025 42:46 Transcription Available


    You’re not supposed to get horny or talk about sex in church, but Brandon Kyle Goodman is not your normal pastor. In their new off-Broadway show HEAUX CHURCH, the host of iHeart’s hit podcast “Tell Me Something Messy” reimagines church as a place for queer people to shed their religious trauma, sexual shame, and become happier, more fulfilled lovers. In this episode, Chris and Gabe talk with Goodman about how religious homophobia fucks up queer people’s access to sexual pleasure, highlighting how Brandon’s upbeat Tammy Faye Baker-style sermon - complete with talking penis, vagina and butthole puppets - offers a path to enlightenment. Heaux-llelujah! Follow Sniffies' Cruising Confessions: cruisingconfessions.com Try Sniffies: sniffies.com Follow Sniffies on Social: Instagram: instagram.com/sniffiesapp X: x.com/sniffiesapp TikTik: tiktok.com/@sniffiesapp Follow the hosts: Gabe Gonzalez: instagram.com/gaybonez Chris Patterson-Rosso: instagram.com/cprgivesyoulife Guests featured in this episode: Brandon Kyle Goodman instagram.com/brandonkylegoodman/ Heaux Church at Ars Nova arsnovanyc.com/events/heaux/See omnystudio.com/listener for privacy information.

    Broads Next Door
    Rewind: The Body Kept The Score- Modern Medical Nightmares & Experiments

    Broads Next Door

    Play Episode Listen Later Oct 30, 2025 84:20 Transcription Available


    Grab your consent forms (but don't sign them yet) and your government-issued fetal monitoring bracelet, because today we're getting a broader understanding of what happens when people aren't treated like people but like data, vessels, and experiments. The body keeps the score- even when it's for medical horror stories. From Adriana Smith, kept alive against her will to serve as a human incubator under Georgia's abortion laws, to Henrietta Lacks, whose cells were stolen, immortalized, and monetized without her knowledge or family's consent, this episode unpacks the long, horrifying legacy of unethical medical research in America.We'll walk through the Tuskegee Syphilis Study, the Holmesburg Prison experiments, the HIV-tainted blood scandal that infected kids like Ryan White, while the government spent more money on the Tylenol murders than AIDS research. And this isn't ancient history, it's happening today- not just with Adriana Smith, or Terri Schiavo as a human prop before her but with forced sterilizations, CRISPR babies, and what happens when “the greater good” doesn't include you.This isn't an anti-science episode. I'm pro-science, but not when the most marganilzed among us have to die for it. And in a world where women, people of color, and the poor are still being used, sometimes even after death- it's more important than ever to ask:Who gets to be a patient? And who's just a test subject?(Originally released May 2025)Become a supporter of this podcast: https://www.spreaker.com/podcast/broads-next-door--5803223/support.

    Creator to Creator's
    Creator to Creators S7 Ep 63 I.K.P

    Creator to Creator's

    Play Episode Listen Later Oct 30, 2025 35:32 Transcription Available


    https://www.ikp.meYoutubeSpotifyInstagramBio K.P. (The Infamous King of Positivity) is a first-generation Honduran American of Garifuna descent and a non-binary rapper and producer whose every move is intentional. From their stage name to their sonic palette, I.K.P. creates with layered purpose.Their latest single “FTW” is a high-voltage anthem built to energize your morning, fuel your workout, or soundtrack your world domination. The track's rattling drums and bass, combined with an eerie and dominant melody, drive a sense of urgency that perfectly matches I.K.P.'s electrifying performance.“I want them to feel unstoppable. Whatever you're doing, you're doing it for the win, and you'reundeniable,” they share.I.K.P.'s writing process is as fluid as it is instinctive. Sometimes they write with pen and pad, other times they record voice notes or use their phone's notes app.“Inspiration strikes in fragments or floods. As they say, you don't gotta get ready if you stay ready.”In a landscape where many artists cling to one sound, I.K.P. thrives in versatility. Whether it's boom bap, drill, reggae, or Latin rhythms, they co-produce and collaborate across styles, honoring Hip-Hop's hybrid roots and their own Afro-Caribbean heritage.“I gravitate towards a lot of things and I don't like to be in a box. I do a lot of co-producing with a multifaceted team. I love Hip-Hop so much because you can make all these hybrid styles make sense.”Their sonic range mirrors a life of movement and resilience. Raised in Norfolk, Virginia after their family emigrated from Honduras, I.K.P. also served over five years in the Marines. Growing up near Portsmouth, they drew early inspiration from Missy Elliott's boundary-breaking creativity.The name I.K.P. represents more than music. It embodies advocacy and empowerment. Their stage name was inspired by their mission to combat the stigma surrounding HIV-positive diagnoses and to use art as a tool for visibility and strength among marginalized communities.“I decided I wasn't going to let things that happened to me define how I saw the world. I wanted to show people who looked like me and lived like me that they could gain a sense of power. And if they didn't know how to do it for themselves, I could show them that it could be done.”I.K.P. also explores the intersection of rap, pop culture, and the evolving LGBTQIA+ experience, acknowledging both the progress and the challenges that remain. They reference artists like Kevin Abstract, Tyler The Creator, Lil Nas X, Young M.A, Steve Lacy, and Syd, trailblazers who continue to push the conversation forward.“It's about self-actualization. Whether you're Black, gay, and/or queer, you're often kept out of certain rooms and conversations. I want to show people that you can always take control and be free.”For I.K.P., rap is a ritual, a reflection of joy, pain, and transformation.“I want to continue to speak for those who feel like they don't have a voice or that their voice is being suppressed. Hip-Hop has always been a tool of progression and evolution, and I just want to continue that tradition,” they said.Their fanbase, affectionately known as #PozFriendlies, can expect a wave of new releases following the success of their fourth full-length project 11:11 | eleven eleven released in 2021. I.K.P. is also expanding their BLOCK SPINNINseries on TikTok and Instagram, a Stereogum-inspired chronicle exploring the history of Billboard Hot 100 hits.Become a supporter of this podcast: https://www.spreaker.com/podcast/creator-to-creators-with-meosha-bean--4460322/support.

    NECA in the Know
    Episode 178: What's Happening with STIs?

    NECA in the Know

    Play Episode Listen Later Oct 30, 2025 14:29


    This week, Marianna sits down with John Faragon to talk about new data released from the Centers for Disease Control regarding sexually transmitted infections. Learn all about the rates of infections such as chlamydia, gonorrhea, and varying types of syphilis, and why this matters for you as an HIV care provider. -- Help us track the number of listeners our episode gets by filling out this brief form! (https://www.e2NECA.org/?r=AQX7941)--Want to chat? Email us at podcast@necaaetc.org with comments or ideas for new episodes. --Check out our free online courses: www.necaaetc.org/rise-courses--Download our HIV mobile apps:Google Play Store: https://play.google.com/store/apps/developer?id=John+Faragon&hl=en_US&gl=USApple App Store: https://apps.apple.com/us/developer/virologyed-consultants-llc/id1216837691

    Well, Well, Well
    20 Years of Well Well Well: 2015 Revisited

    Well, Well, Well

    Play Episode Listen Later Oct 30, 2025 51:38


    Show alum Renee Thompson joins us as guest co-host on a walk down memory lane circa 2015, discussing the Marriage Equality debate and Thorne Harbour's shift from HIV and gay men's health to the broader LGBTIQA+ communities. We also hear from outgoing Thorne Harbour Health CEO Simon Ruth about his 12 years at the organisation and the issues affecting our communities during that time. Check out our other JOY Podcasts for more on LGBTIQ+ health and wellbeing at joy.org.au/wellwellwell. If there's something you'd like us to explore on the show, send through ideas or questions at wellwellwell@joy.org.au Find out more about LGBTIQ+ services and events in Victoria and South Australia at thorneharbour.org and samesh.org.au.

    Think Out Loud
    Portlander's global health development podcast centers voices of USAID workers amid agency's dismantling

    Think Out Loud

    Play Episode Listen Later Oct 29, 2025 18:53


    In February, the Trump administration announced cuts to more than 90% of USAID’s foreign aid contracts and $60 billion in overall assistance around the world. In July, the agency’s remaining programs were brought under the control of the State Department. Thousands of USAID staff and contractors working in the US and around the world have been fired or laid off, including Portlander Leah Petit. A global health professional for nearly 20 years, Petit was a senior program advisor at USAID’s Office of HIV/AIDS when she lost her job in late January. Her projects focused on strengthening local health systems in Africa and Asia to sustain long-term HIV prevention, monitoring and treatment efforts.    In August, Petit embarked on a new career when she launched “Global Development Interrupted,” a podcast she hosts and produces featuring former USAID workers who help dispel misconceptions about the agency’s work overseas and how it has benefited Americans here. Established nearly 65 years ago, USAID has delivered lifesaving humanitarian assistance and medicines, mobilized to halt the spread of deadly diseases like Ebola, expanded access to clean drinking water and sanitation, along with countless other relief and development programs. Petit joins us to share more details about her podcast and what’s at stake when the US reverses its leadership on international aid, including the millions of lives that are expected to be lost with the dismantling of USAID.  

    Public News Service
    PNS Daily Newscast: October 29, 2025

    Public News Service

    Play Episode Listen Later Oct 29, 2025 6:00


    Hurricane Melissa plows across Jamaica, its eye now moving toward Cuba; Israel launches strikes on Gaza after Netanyahu orders 'powerful' attacks; HIV outbreak in ME shows risk of federal crackdown on homelessness; Iowans face changes to Medicare plans; WI Farmers Union calls for policy investments in rural Wisconsin.

    Public News Service
    PNS Daily Newscast: October 29, 2025

    Public News Service

    Play Episode Listen Later Oct 29, 2025 6:00


    Hurricane Melissa plows across Jamaica, its eye now moving toward Cuba; Israel launches strikes on Gaza after Netanyahu orders 'powerful' attacks; HIV outbreak in ME shows risk of federal crackdown on homelessness; Iowans face changes to Medicare plans; WI Farmers Union calls for policy investments in rural Wisconsin.

    Real Talk: Eosinophilic Diseases
    TSLP and EoE: Exploring the Science Behind a Potential Treatment Target

    Real Talk: Eosinophilic Diseases

    Play Episode Listen Later Oct 29, 2025 33:10


    Co-hosts Ryan Piansky, a graduate student and patient advocate living with eosinophilic esophagitis (EoE) and eosinophilic asthma, and Holly Knotowicz, a speech-language pathologist living with EoE who serves on APFED's Health Sciences Advisory Council, interview Dr. Andrew Lee, Vice President, Clinical Research at Uniquity Bio, about Thymic Stromal Lymphopoietin (TSLP) and eosinophilic esophagitis (EOE). Disclaimer: The information provided in this podcast is designed to support, not replace, the relationship between listeners and their healthcare providers. Opinions, information, and recommendations shared in this podcast are not a substitute for medical advice. Decisions related to medical care should be made with your healthcare provider. Opinions and views of guests and co-hosts are their own.   Key Takeaways: [:49] Co-host Ryan Piansky introduces the episode, brought to you thanks to the support of Education Partners Bristol Myers Squibb, GSK, Sanofi, Regeneron, and Takeda. Ryan introduces co-host Holly Knotowicz.   [1:13] Holly introduces today's topic, Thymic Stromal Lymphopoietin (TSLP) and eosinophilic esophagitis (EOE), and today's guest, Dr. Andrew Lee, Vice President, Clinical Research at Uniquity Bio.   [1:36] Dr. Lee has nearly 20 years of experience in the clinical development of new vaccines, biologics, and drugs. Holly welcomes Dr. Lee.   [1:52] Dr. Lee trained in internal medicine and infectious diseases.   [1:58] Dr. Lee has been fascinated by the immune system and how it can protect people against infections, what happens when immunity is damaged, as in HIV and AIDS, and how to apply that knowledge to boost immunity with vaccines to prevent infections.   [2:16] Dr. Lee led the clinical development for a pediatric combination vaccine for infants and toddlers. It is approved in the U.S. and the EU.   [2:29] Dr. Lee led the Phase 3 Program for a monoclonal antibody to prevent RSV, a serious infection in infants. That antibody was approved in June 2025 for use in the U.S.   [2:44] In his current company, Dr. Lee leads research into approaches to counteract an overactive immune system. They're looking at anti-inflammatory approaches to diseases like asthma, EoE, and COPD.   [2:58] Dr. Lee directs the ongoing Phase 2 studies that they are running in those areas.   [3:28] Dr. Lee sees drug development as a chance to apply cutting-edge research to benefit people. He trained at Bellevue Hospital in New York City in the 1990s.   [3:40] When Dr. Lee started as an intern, there were dedicated ICU wards for AIDS patients because many of the sickest patients were dying of AIDS and its complications.    [3:52] Before the end of Dr. Lee's residency, they shut down those wards because the patients were on anti-retroviral medications and were doing so well that they were treated as outpatients. They didn't need dedicated ICUs for AIDS patients anymore.   [4:09] For Dr. Lee, that was a powerful example of how pharmaceutical research and drug regimen can impact patients' lives for the better by following the science. That's what drove Dr. Lee to go in the direction of research.   [4:48] Dr. Lee explains Thymic Stromal Lymphopoietin (TSLP). TSLP serves as an alarm signal for Type 2 or TH2 inflammation, a branch of the immune responses responsible for allergic responses and also immunity against parasites.   [5:17] When the cells that line the GI tract and the cells that line the airways in our lungs receive an insult or an injury, they get a danger signal, then they make TSLP.   [5:28] This signal activates other immune cells, like eosinophils and dendritic cells, which make other inflammatory signals or cytokines like IL-4, IL-13, and IL-5.   [5:47] That cascade leads to inflammation, which is designed to protect the body in response to the danger signal, but in some diseases, when there's continued exposure to allergens or irritants, that inflammation goes from being protective to being harmful.   [6:15] That continued inflammation, over the years, can lead to things like the thickened esophagus with EoE, or lungs that are less pliant and less able to expand, in respiratory diseases.   [6:48] Dr. Lee says he thinks of TSLP as being a master switch for this branch of immune responses. If you turn on TSLP, that turns on a lot of steps that lead to generating an allergic type of response.   [7:06] It's also the same type of immune response that can fight off parasite infections. It's the first step in a cascade of other steps generating that type of immune response.   [7:30] Dr. Lee says people have natural genetic variation in the genes that incur TSLP.   [7:38] Observational studies have found that some people with genetic variations that lead to higher levels of TSLP in their bodies had an increased risk for allergic inflammatory diseases like EoE, atopic dermatitis, and asthma.   [8:13] Studies like the one just mentioned point to TSLP being important for increased risk of developing atopic types of diseases like EoE and others. There's been some work done in the laboratory that shows that TSLP is important for activating eosinophils.    [8:38] There's accumulating evidence that TSLP activation leads to eosinophil activation, other immune cells, or white blood cells getting activated.   [9:07] Like a cascade, those cells turn on T-cells and B-cells, which are like vector cells. They lead to direct responses to fight off infections, in case that's the signal that leads to the turning on TSLP.   [9:48] Ryan refers to a paper published in the American Journal of Gastroenterology exploring the role of TSLP in an experimental mouse model of eosinophilic esophagitis. Ryan asks what the researchers were aiming to find.   [10:00] Dr. Lee says the researchers were looking at the genetic studies we talked about, the observational studies that are beginning to link more TSLP with more risk for EoE and those types of diseases.   [10:12] The other type of evidence that's accumulating is from in vitro (in glass) experiments or test tube experiments, where you take a couple of cells that you think are relevant to what's going on.   [10:28] For example, you could get some esophageal cells and a couple of immune cells, and put TSLP into the mix, and you see that TSLP leads to activation of those immune cells and that leads to some effects on the esophageal cells.   [10:42] Those are nice studies, but they're very simplified compared to what you can do in the body. These researchers were interested in extending those initial observations from other studies, but working in the more realistic situation of a mouse model.   [11:00] You have the whole body of the mouse being involved. You can explore what TSLP is doing and model a disease that closely mimics what's happening with EoE in humans.   [12:23] They recreated the situation of what seems to be happening in EoE in people. We haven't identified it specifically, but there's some sort of food allergen in patients with EoE that the immune system is set off by.   [12:55] What researchers are observing in this paper is that in these mice that were treated with oxazolone, there is inflammation in the esophagus, an increase in TSLP levels, and eosinophils going into the esophageal tissues.   [13:15] Dr. Lee says, that's one of the main ways we diagnose EoE; we take a biopsy of the esophagus and count how many eosinophils there are. Researchers saw similar findings. The eosinophil count in the esophageal tissues went way up in these mice.    [13:34] Researchers also saw other findings in these mice that are very similar to EoE in humans, such as the esophageal cells lining the esophagus proliferating. They even saw that new blood vessels were being created in that tissue that's getting inflamed.   [14:00] Dr. Lee thinks it's a very nice paper because it shows that correlation: Increase TSLP and you see these eosinophils going to the esophagus, and these changes that are very reminiscent of what we see in people with EoE.   [14:51] In this paper, the mice made the TSLP, and researchers were able to measure the TSLP in the esophageal tissue. The researchers didn't introduce TSLP into the mice. The mice made the TSLP in response to being repeatedly exposed to oxazolone.   [15:20] That's key to the importance of the laboratory work. The fact that the TSLP is made by the mice is important. It makes it a very realistic model for what we're seeing in people.   [15:41] In science, we like to see correlation. The researchers showed a nice correlation.   [15:46] When TSLP went up in these mice, and the mice were making more TSLP on their own, at the same time, they saw all these changes in the esophagus that look a lot like what EoE looks like in people.    [16:01] They saw the eosinophils coming into the esophagus. They saw the inflammation go up in the esophagus. What Dr. Lee liked about this paper is that they continued the story.   [16:15] The researchers took something that decreases TSLP levels, an antibody that binds to and blocks TSLP, and when they did that, they saw the TSLP levels come down to half the peak level.   [16:35] Then they saw improvement in the inflammation in the esophagus. They saw that the amount of eosinophils decreased, and the multiplication of the esophageal cells went down. The number of new blood vessels went down after the TSLP was reduced.   [16:53] Dr. Lee says, you see correlation. The second part is evidence for causation. When you take TSLP away, things get better. That gives us a lot of confidence that this is a real finding. It's not just observational. There is causation evidence here.   [18:26] Ryan asks if cutting TSLP also help reduce other immune response cells. Dr. Lee says TSLP is the master regulator for this Type 2 inflammation. It definitely touches and influences other cells besides eosinophils.   [18:44] TSLP affects dendritic cells, which are an important type of immune cell, like a coordinating cell that instructs other cells within the immune system what to do. In this paper, they looked at a lot of other effects of TSLP on the tissues of the body.   [19:10] Dr. Lee says, There's a lot of research on TSLP, and one of the reasons we're excited about the promise of TSLP is that it's so far upstream; so much of the beginning, that it's affecting other cells.   [19:29] Its effects could be quite broad. If we're able to successfully block TSLP, we could block a lot of different effects.   [19:40] One treatment for EoE is dupilumab, which blocks IL-4 and IL-13 specifically, and that works well, but TSLP has the potential to have an even greater effect than blocking IL-4 and IL-13, since it is one step before turning on IL-4 and IL-13.    [20:14] That's one of the reasons researchers are excited about the promise of blocking TSLP. There are studies ongoing of TSLP blockers in people with EoE.   [20:34] Ryan asks if there are negative repercussions from blocking TSLP. Dr. Lee says in this study and in people, we are not completely blocking TSLP by any means. There will still be residual TSLP activated, even with very potent drugs.   [21:01] In the study, they block TSLP about 50%‒60%. TSLP is involved in immunity against parasites. In studies with people, they make sure not to include anybody who has an active parasitic infection. A person under treatment should not be in a study.   [21:27] Dr. Lee says we haven't seen any problems with parasitic infections becoming more severe, but that is a theoretical possibility, so for that reason, in studies with TSLP blockers, we generally exclude patients with known parasitic infections.   [22:17] What excited Dr. Lee in this paper was that they showed that when you block TSLP in the mice, then you get real effects in their tissues. Eosinophils went away. The thickening of the basal layers in the esophagus got much better.   [22:38] That kind of real effect reflected in the tissue is super exciting to see. That gives us more confidence that this could work in people, since we're seeing it in a realistic whole-body model in the mice.   [23:12] Dr. Lee says there are ongoing clinical studies on TSLP blockers for EoE. His company is studying an antibody that blocks TSLP in eczema, COPD, and EoE. One of the exciting things about immunology is that it affects many different parts of the body.   [23:42] EoE is associated with other immune-type disorders. There's a high percentage of patients with EoE who have other diseases. EoE coexists with asthma, atopic dermatitis, and chronic rhinitis.   [24:09] It's exciting that if you figure out something that's promising for one disease that TSLP affects, it could have very broad-ranging implications for a variety of diseases.   [24:22] Ryan shares his experience of his doctor talking to him about a TSLP blocker, tezepelumab, as a potential option when it's out of clinical trials. It would target something a little higher up the chain and help with some of his remaining symptoms.   [24:59] Ryan is excited to hear that this research is so encouraging and how it could potentially help treat EoE, asthma, and other conditions, all at once.   [25:16] Dr. Lee says that being in these later-stage studies is super exciting. If these late-stage trials are successful, the next step is to apply for regulatory approval with the various agencies around the world.   [26:40] Dr. Lee shares one takeaway for listeners to remember. Think of TSLP as an alarm that turns on inflammation. He compares TSLP to turning on an alarm during a robbery. There are multiple steps designed to protect the bank and the money.   [27:20] To extend that analogy, with TSLP, once you turn it on, all these other steps are going to happen. Inflammation is designed to protect the body. It's a protective response. If there's an infection, it can clear the infection.   [27:38] If the infection persists, as in HIV, the immune response, which is protective and beneficial, eventually becomes damaging. It becomes dysfunctional. In EoE, if you continually eat the allergic food, the inflammation becomes damaging to the esophagus.   [28:27] Long-term inflammation leads to replacing the normal esophageal tissue with fibrotic tissue, and that's why the esophagus eventually gets hardened and less able to let the food go through.   [28:40] In respiratory diseases, the soft tissue of the lung gets replaced with thicker tissue, and the lung is not able to expand.   [28:54] Dr. Lee says he people to think about TSLP as this master alarm switch. We hope that if you could turn off that TSLP, you could then avoid a lot of the complications that we see with chronic inflammation in these conditions.   [29:14] We're hopeful that you could even take away the symptoms that you see in these diseases, make patients feel better, and with extended treatment, you could begin to reverse some of the damage resulting from inflammation.   [29:32] Ryan likes that analogy and how Dr. Lee has concisely explained these complicated concepts.   [29:51] Dr. Lee thanks Holly and Ryan and adds one more plea to listeners. Please consider getting involved with research. Clinical trials cannot be done without patients. We need patients to advance new treatments.   [30:27] Researchers like Dr. Lee spend a lot of time thinking about how to make the studies not only informative but also fair to patients who decide to become involved. It's a lot of work and a fair amount of time commitment.   [30:44] If you don't want to be in a study, you can help by being on a patient feedback panel and reviewing protocols and informed consents. Follow your interests. Think about getting involved with research, however you can.   [31:06] Ryan and Holly are very grateful for the community, with so many wonderful clinicians and researchers, and so many patients who are willing to volunteer their time and their data to help researchers find better solutions going forward.   [31:26] Ryan thanks Dr. Lee for coming on and putting out that call to action. It's a great reminder for listeners and the patients in the community to look for those opportunities. Chat with your physician. Go to APFED's website. There's a link to active clinical trials.   [31:47] For our listeners who want to learn more about eosinophilic disorders, we encourage you to visit apfed.org and check out the links in the show notes below.   [31:53] For those looking to find specialists who treat eosinophilic disorders, we encourage you to use APFED's Specialist Finder at apfed.org/specialist.   [32:01] If you'd like to connect with others impacted by eosinophilic diseases, please join APFED's online community on the Inspire Network at apfed.org/connections.   [32:11] Ryan thanks Dr. Andrew Lee for joining us today. We learned a lot. Holly also thanks APFED's Education Partners Bristol Myers Squibb, GSK, Sanofi, Regeneron, and Takeda for supporting this episode.   Mentioned in This Episode: Andrew Lee, M.D., VP Clinical Research, Uniquity Bio   "A Mouse Model for Eosinophilic Esophagitis (EoE)" Current Protocols, Wiley Online Library   APFED on YouTube, Twitter, Facebook, Pinterest, Instagram Real Talk: Eosinophilic Diseases Podcast apfed.org/specialist apfed.org/connections apfed.org/research/clinical-trials   Education Partners: This episode of APFED's podcast is brought to you thanks to the support of Bristol Myers Squibb, GSK, Sanofi, Regeneron, and Takeda.   Tweetables:   "I see drug development as a chance to apply cutting-edge research to benefit people." — Andrew Lee, M.D.   "When the cells that line the GI tract and the cells that line the airways in our lungs receive an insult or an injury, they get a danger signal, then they make TSLP." — Andrew Lee, M.D.   "Observational studies have found that some people with genetic variations that lead to higher levels of TSLP in their bodies had an increased risk for allergic inflammatory diseases like EoE, atopic dermatitis, and asthma." — Andrew Lee, M.D.   "There's a lot of research on TSLP, and one of the reasons we're excited about the promise of TSLP is that it's so far upstream; so much of the beginning, that it's affecting other cells." — Andrew Lee, M.D.   "Please consider getting involved with research. We can't do these clinical trials without patients. We need patients to advance new treatments for patients." — Andrew Lee, M.D.

    Dr. Berg’s Healthy Keto and Intermittent Fasting Podcast
    The HIDDEN Killer Deadlier than the Plague

    Dr. Berg’s Healthy Keto and Intermittent Fasting Podcast

    Play Episode Listen Later Oct 28, 2025 12:27


    One in 4 people is infected with this silent killer disease that's deadlier than the plague. You may even have this infection! Find out about this deadly microbial threat and how to stay healthy so you don't become the next victim. 0:00 Introduction: Infectious disease deadlier than the plague 1:30 Latent infections 2:59 Tuberculosis facts 4:39 Tuberculosis and vitamin D7:38 Immune system function8:20 Sun exposure and infrared rays Many people are infected with a disease that's worse than the plague! The plague killed 200 million people, and in total, this bacterium has killed 1 billion! It's the world's deadliest infectious disease and kills more people than HIV and malaria combined. It kills around 1.3 million people each year, yet you don't hear much about it. Latent infections such as herpes, EBV, CMV, HPV, and Hepatitis B and C are able to go in and out of remission. Today, we're going to talk about the pathogen that gives you tuberculosis.Tuberculosis (TB) doesn't evade the immune system, it invades it. TB hides inside the macrophage, which is responsible for cleaning up bacteria and infections in the body. TB affects more people in the northern hemisphere away from the equator, and its incidence increases in the winter. Older people or those with type 2 diabetes, HIV, or low vitamin D are at an increased risk of an active TB infection. TB blocks the vitamin D receptor, which lowers your immune function. There was an uptick in TB outbreaks in the 80s when sun phobia was promoted. This campaign significantly reduced vitamin D levels by reducing sun exposure. Before the development of antibiotics, people with tuberculosis would go to sanatoriums for fresh air and sunlight exposure. Cod liver oil was also shown to be beneficial for people with tuberculosis infections.The immune system destroys TB with a compound called cathelicidin, a broad-spectrum antimicrobial that depends on vitamin D. Not only is the sun vital for vitamin D production, but it also exposes you to infrared light. Infrared reverses mitochondrial damage and can increase vitamin D signaling, further protecting you from a TB infection. Dr. Eric Berg DC Bio:Dr. Berg, age 60, is a chiropractor who specializes in Healthy Ketosis & Intermittent Fasting. He is the Director of Dr. Berg Nutritionals and author of the best-selling book The Healthy Keto Plan. He no longer practices, but focuses on health education through social media.Disclaimer: Dr. Eric Berg received his Doctor of Chiropractic degree from Palmer College of Chiropractic in 1988. His use of “doctor” or “Dr.” in relation to himself solely refers to that degree. Dr. Berg is a licensed chiropractor in Virginia, California, and Louisiana, but he no longer practices chiropractic in any state and does not see patients, so he can focus on educating people as a full-time activity, yet he maintains an active license. This video is for general informational purposes only. It should not be used to self-diagnose, and it is not a substitute for a medical exam, cure, treatment, diagnosis, prescription, or recommendation. It does not create a doctor-patient relationship between Dr. Berg and you. You should not make any change in your health regimen or diet before first consulting a physician and obtaining a medical exam, diagnosis, and recommendation. Always seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition.

    40 Days for Life Podcast
    Birth Control Is a Blessing...--PODCAST Season 10, episode 43

    40 Days for Life Podcast

    Play Episode Listen Later Oct 28, 2025 66:02


    Contraception is designed to prevent untended pregnancies. Unintended pregnancies account for the majority of abortions. So it would seem that contraception reduces the number of abortions and that birth control is a blessing. But is that true? It's a disputed matter—especially among pro-lifers. On this episode of The 40 Days for Life Podcast, we answer the question: Is contraception a blessing or a curse? NOTE: On this episode, we discuss Dr. Edward Green's explanation of the concept of risk compensation. Dr. Green describes the phenomenon using the examples of HIV and sun exposure. We apply the principle to contraception and pregnancy. See this interview for more information: bbc.co.uk/blogs/ni/2009/03/aids_expert_who_defended_the_p.html

    Infectious Disease Puscast
    Infectious Disease Puscast #92

    Infectious Disease Puscast

    Play Episode Listen Later Oct 28, 2025 36:55


    On episode #92 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 10/9/25 – 10/22/25. Host: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Long-term clinical, immunologic, and viral reservoir outcomes in children treated with VRC01LS and 10-1074 monoclonal antibodies in the Tatelo Study (CID) Resistance Analyses of Lenacapavir, Emtricitabine/Tenofovir Alafenamide and Emtricitabine/Tenofovir Disoproxil Fumarate in the PURPOSE 1 and 2 Studies (JID) Susceptibility of measles virus to WHO hand rubs, oral and surface disinfectants (OFID) Measles without rash during acute febrile illness surveillance in Tanzania, 2023-2024 (CID) The 2025 Centers for Disease Control and Prevention Non-Occupational HIV Post-Exposure Prophylaxis Guidelines (CID) Bacterial Paratyphoid fever and relapsing fever in 1812 Napoleon's devastated army (Current Biology) Mass Administration of Azithromycin to Infants in Mali to Reduce Mortality (NEJM) Efficacy and safety of tedizolid in the treatment of acute bacterial skin and skin-structure infections (CMI: Clinical Microbiology and Infection) Zoonotic Escherichia coli and urinary tract infections in Southern California (mBio) Cefdinir Versus Cephalexin for the Treatment of Uncomplicated Urinary Tract Infections (OFID) Fungal The Last of US Season 2 (YouTube) Antagonistic in vitro interaction between olorofim and voriconazole against Aspergillus fumigatus (Journal of Antimicrobial Chemotherapy) Parasitic Miscellaneous CARB Your Enthusiasm: An Ethics-Informed Analysis for Clinicians of the US National Action Plan for Combating Antibiotic-Resistant BacteriaCID) Infection Control in Carceral Facilities (CID) Infection Prevention and Control in Carceral Settings (CID) The Challenge of Malignancies in HIV-1, Beyond Immune Activation and Back to Decreased Immune Surveillance (Journal of AIDS & Clinical Research) SARS-CoV-2 mRNA vaccines sensitize tumours to immune checkpoint blockade (Nature) TWiV 1265: mRNA vaccines make cancer treatment great again (microbeTV) Infected With the Academic Bug (CID) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.

    The Daily Friend Show
    Can SA end HIV?

    The Daily Friend Show

    Play Episode Listen Later Oct 28, 2025 33:37


    Nicholas Lorimer and Makone Maja discuss South Africa's opportunity to end HIV if it makes the right choices. They also discuss South Africans having a favourable view of military rule, and how many people actually benefit from BEE. Website · Facebook · Instagram · Twitter

    True Murder: The Most Shocking Killers
    A TOWN WITHOUT PITY—Jason Vuic

    True Murder: The Most Shocking Killers

    Play Episode Listen Later Oct 27, 2025 83:56 Transcription Available


    In the 1980s, the tiny town of Arcadia, Florida, was “fifty miles and fifty years from Sarasota.” With its cowboy roots, low-wage agricultural industries, and violent frontier history, Arcadia was a curious mix of the desolate ranchlands of West Texas and the stately homes and bitter race relations of the South. In A Town without Pity, award-winning author Jason Vuic recounts two heartbreaking stories from Arcadia that rose to national prominence at the end of the Reagan era and forced the town to reckon with not only AIDS hysteria but also the legacies of a racist past. This book delves into the case of James Richardson, a Black migrant worker accused in 1967 of poisoning his seven children. Richardson spent twenty years in prison due to suppressed evidence for a crime he didn't commit. Vuic also tells the story of the public mistreatment of the three Ray brothers, white school-age children with hemophilia who contracted the HIV virus from a tainted medicine called factor VIII. The Rays were barred from attending their local church and school, and when their house burned down in a mysterious arson, reporters dubbed Arcadia the “town without pity.”Through extensive use of newspapers, court records, and interviews, Vuic shows how the actions of authorities and residents left little room for the voices that spoke up against bias, harassment, and coercion. At the same time, this cautionary tale places Arcadia as a microcosm of many small towns in the late twentieth-century United States, reminding readers of the staying power of social divisions and prejudice even after the achievements of the civil rights movement. A TOWN WITHOUT PITY: AIDS, Race, and Resistance in Florida's Deep South—Jason Vuic

    The Sleep Is A Skill Podcast
    237: Lynne Peeples, Science Journalist & Author of The Inner Clock: Reprogram Your Circadian Rhythm: The Secret Code of Sleep & Health

    The Sleep Is A Skill Podcast

    Play Episode Listen Later Oct 27, 2025 36:16


    Lynne Peeples is an author and journalist covering science, health, and the environment. Her writing has appeared in The Guardian, Scientific American, Nature, HuffPost, NBC News, The Atlantic, and other publications. Before becoming a journalist, she crunched numbers as a biostatistician for HIV clinical trials and environmental health studies. Peeples is a recipient of an MIT Knight Science Journalism fellowship and an Alfred P. Sloan Foundation book grant. She also holds master's degrees in biostatistics from the Harvard School of Public Health and in science journalism from New York University. She lives in Seattle. SHOWNOTES:

    BOSS Business of Surgery Series
    Ep. 204 [MVP] When the wrong job is hurting you with Dr. Sara Rasmussen

    BOSS Business of Surgery Series

    Play Episode Listen Later Oct 27, 2025 61:27


    Summary This podcast episode from the Boss Surgery Series features Dr. Amy Vertries interviewing Dr. Sarah Rasmussen, a pediatric transplant surgeon, about her experience of being in the wrong job and navigating a career transition. Dr. Rasmussen shares her journey from working at the University of Virginia (UVA) to Seattle Children's Hospital and then to a new position that better aligned with her career goals and values. Dr. Rasmussen begins by describing her background as a Gen-Xer born in West Virginia who initially planned to practice medicine with her father. She pursued an MD-PhD program at WVU in 1997, focusing on HIV research at the National Cancer Institute. During her medical training, she discovered her passion for surgery during rotations and completed her residency at Virginia Commonwealth University followed by a pediatric surgery fellowship at Johns Hopkins. She then worked at UVA from 2011 to 2020, where she established a pediatric liver transplant program in partnership with Children's Hospital of Pittsburgh. Dr. Rasmussen explains that leadership changes at UVA led to her role being reduced from performing 42 liver transplants annually to being limited to only pediatric cases (about 5 per year). This significant reduction in surgical volume prompted her to accept a position at Seattle Children's Hospital as the surgical director of pediatric liver transplant, which she accepted just before the COVID-19 pandemic began in early 2020. At Seattle Children's, Dr. Rasmussen encountered challenges that made her realize she was in the wrong job. Despite the hospital performing more transplants (13-15 liver transplants and 30 kidney transplants annually), she faced issues with case allocation, micromanagement of her decisions, and resistance to her suggestions for improving processes. After 18 months, she compiled data showing her limited involvement in transplant cases and presented it to leadership, hoping for change. Instead, this led to increased scrutiny of her abilities. Dr. Rasmussen describes how the job stress affected her health, causing panic attacks, chest pain, and dangerously high blood pressure. With support from her family and through Dr. Vertries' coaching program, she decided to explore other opportunities. She interviewed at four institutions and found a position with a partner who shared her vision and valued her contributions. In her new role, Dr. Rasmussen found a supportive environment where her partner encourages her growth, helps her through complications, and values her strengths. She shares how her new partner supported her through a surgical complication by not letting her isolate herself and helping her move past self-doubt. He also encourages her to take on challenging cases, such as performing laparoscopic procedures on very small infants. The conversation concludes with reflections on the importance of finding the right job fit, the impact of career decisions on family, and how having the right partner can make a significant difference in professional growth and satisfaction. Chapters Dr. Rasmussen's Background and Early Career Path ‎ 00:02:12 Dr. Sarah Rasmussen introduces herself as a Gen-Xer born in West Virginia. She initially planned to practice medicine with her father but became interested in research during medical school. She joined an MD-PhD program at WVU in 1997, focusing on HIV research at the National Cancer Institute. During her clinical rotations, she discovered her passion for surgery, which engaged "all parts of her brain." She completed her residency at Virginia Commonwealth University and a pediatric surgery fellowship at Johns Hopkins. From 2011 to 2020, she worked at the University of Virginia (UVA) as an assistant professor, where she also completed an additional fellowship in abdominal transplant surgery. At UVA, she was active in research, clinical work, teaching, and helped establish a pediatric liver transplant program in partnership with Children's Hospital of Pittsburgh. Transition to Seattle Children's Hospital During the Pandemic ‎ 00:05:21 Dr. Rasmussen explains that leadership changes at UVA led to her role being reduced from performing 42 liver transplants annually to being limited to only pediatric cases (about 5 per year). This significant reduction prompted her to accept a position as surgical director of pediatric liver transplant at Seattle Children's Hospital. She signed her offer letter just before the COVID-19 pandemic began, making the transition particularly challenging as it occurred during social distancing measures. Dr. Rasmussen was attracted to Seattle Children's because they performed more transplants (13-15 liver transplants and 30 kidney transplants annually), and she believed she would have a good working relationship with the program head who had similar training. Challenges at Seattle Children's Hospital ‎ 00:09:27 Dr. Rasmussen describes her initial positive reception at Seattle Children's but quickly noticed concerning dynamics between surgeons during her observation of a liver-kidney transplant on her second day. Despite her efforts to integrate into the team, she faced significant challenges: her clinical decisions were micromanaged, her requests for time off were complicated by "unwritten rules," and she was often excluded from transplant cases because "fellows needed the experience." After 12 months, she realized that her situation wasn't improving despite her efforts to be helpful and engaged. After 18 months, she compiled data showing her limited involvement in transplant cases (only 20% of livers and 15% of kidneys despite being on call 33% of the time) and presented it to leadership, hoping for change. Instead of addressing her concerns, this led to increased scrutiny of her abilities. Recognizing the Need for Change ‎ 00:16:45 Dr. Rasmussen sought advice from colleagues but was consistently told that the situation "would never change." She realized that her vision of being a pediatric liver transplant surgeon required meaningful involvement in cases, which wasn't happening at Seattle. In January 2021, she learned of four potential job openings in her field. Initially resistant to moving her family again so soon after relocating during the pandemic, she joined Dr. Vertries' "difficult partner course" hoping to learn how to succeed in her current position. Through the course, she gave herself permission to explore other opportunities and interviewed at all four institutions. Two positions seemed promising, with one standing out immediately because of her connection with the potential new boss. Health Impact and Decision to Leave ‎ 00:25:56 Dr. Rasmussen describes how the job stress severely affected her health, causing panic attacks manifesting as chest pain and dangerously high blood pressure (190/110 with a heart rate of 197). One night after seeing the clinic and call schedule, she couldn't calm down despite trying mindfulness techniques. Her husband witnessed this and declared, "We are done here." Additional factors influencing her decision included the death of a mentor and her mother's illness. Dr. Rasmussen realized that despite her efforts, the team at Seattle Children's was unwilling to accommodate her career needs, which she viewed as a "breach of contract" - not from the institution but from the team that should invest in its members. Family Considerations in Career Decisions ‎ 00:28:55 Dr. Rasmussen discusses the challenge of considering another move so soon after relocating her family during the pandemic. She worried about uprooting her children who had just established connections in Seattle. A turning point came when her oldest child told her, "Mom, I think it's time for you to worry about yourself. I'm going to be okay." For her job interviews, she took the unusual step of requesting that both potential employers bring her entire family for second visits, not just her spouse. She received advice that "how happy do you think your family can be if mom is not happy?" and realized that many children move multiple times during childhood without negative consequences. She also learned that her oldest child had been bullied at their previous school, reinforcing that staying in Virginia might not have been better for her family. Finding the Right Partner and Environment ‎ 00:47:08 Dr. Rasmussen describes how she connected with her new boss by cold-calling him about a position at his former institution and inquiring if he needed a partner in his new program. Their initial conversation revealed shared vision and energy for building a program. Unlike her experience in Seattle, her new boss explicitly stated, "You tell me what you need out of a case, and that's what will happen," emphasizing team function over hierarchy. She contrasts this with her previous experience, noting the difference between a hierarchical environment and one with a shared vision. When she experienced a serious complication in her first liver transplant at the new institution, her partner provided support without judgment, wouldn't let her isolate herself, and eventually told her "it's time to stop" ruminating, while acknowledging that such complications happen to everyone. Growth and Support in the New Position ‎ 00:54:01 Dr. Rasmussen shares how her new environment supports her growth through challenging cases. During her first on-call experience, she consulted on a 1.6-kilogram baby with duodenal atresia. Though initially planning an open procedure, she researched laparoscopic approaches and found evidence supporting minimally invasive surgery for this condition. When she proposed this to her boss, he gave no pushback and even came to observe the successful procedure. Three months later, when she hesitated about performing a laparoscopic cholecystectomy on an eight-week-old baby, her boss reminded her, "Three months ago, you did a lap duodenal atresia repair on a 1.6 kilo baby - get over it," encouraging her to trust her abilities. Dr. Rasmussen appreciates how her partner recognizes when her tendency to overthink is a strength (when writing policies or justifications) and when it's holding her back. Reflections on Career Transitions and Lessons Learned ‎ 01:00:00 Dr. Rasmussen and Dr. Vertries reflect on the lessons learned through this career journey. Dr. Rasmussen acknowledges how she overcame limiting beliefs such as "I can't move because it will hurt my family" and "I can't have an ideal partner." Dr. Vertries notes that Dr. Rasmussen has experienced a "hero's journey" and that her lessons will have an "exponential effect on other people." Dr. Rasmussen expresses gratitude for the opportunity to reflect on how far she's come in a relatively short time, demonstrating that "you can make some pretty life-altering things in a short period of time with a little bit of help." Action Items Dr. Vertries mentioned reaching out to her at bosssurgery.com for help with toxic job situations. ‎ 00:00:35 Dr. Rasmussen suggested asking detailed questions about job expectations and case allocation when interviewing for new positions. ‎ 00:13:54 Dr. Rasmussen recommended bringing family members on second job interviews when considering relocation. ‎ 00:29:58 Dr. Rasmussen advised seeking coaching before leaving a job to process the situation properly. ‎ 00:42:17 Dr. Rasmussen suggested researching evidence-based approaches to surgical techniques when considering new procedures. ‎ 00:55:57

    Afternoon Drive with John Maytham
    SA to roll out twice-yearly HIV jab

    Afternoon Drive with John Maytham

    Play Episode Listen Later Oct 27, 2025 7:33 Transcription Available


    John Maytham speaks to journalist, Mia Malan, of the Bhekisisa Health Journalism Centre, about a new twice-yearly HIV prevention jab that has been approved by the Health Products Regulatory Authority. Presenter John Maytham is an actor and author-turned-talk radio veteran and seasoned journalist. His show serves a round-up of local and international news coupled with the latest in business, sport, traffic and weather. The host’s eclectic interests mean the program often surprises the audience with intriguing book reviews and inspiring interviews profiling artists. A daily highlight is Rapid Fire, just after 5:30pm. CapeTalk fans call in, to stump the presenter with their general knowledge questions. Another firm favourite is the humorous Thursday crossing with award-winning journalist Rebecca Davis, called “Plan B”. Thank you for listening to a podcast from Afternoon Drive with John Maytham Listen live on Primedia+ weekdays from 15:00 and 18:00 (SA Time) to Afternoon Drive with John Maytham broadcast on CapeTalk https://buff.ly/NnFM3Nk For more from the show go to https://buff.ly/BSFy4Cn or find all the catch-up podcasts here https://buff.ly/n8nWt4x Subscribe to the CapeTalk Daily and Weekly Newsletters https://buff.ly/sbvVZD5 Follow us on social media: CapeTalk on Facebook: https://www.facebook.com/CapeTalk CapeTalk on TikTok: https://www.tiktok.com/@capetalk CapeTalk on Instagram: https://www.instagram.com/ CapeTalk on X: https://x.com/CapeTalk CapeTalk on YouTube: https://www.youtube.com/@CapeTalk567 See omnystudio.com/listener for privacy information.

    The Daily Beans
    Refried Beans | Advice Of Counsel (feat. Anna Bower) | Oct 26, 2023

    The Daily Beans

    Play Episode Listen Later Oct 25, 2025 47:33


    Friday, October 27th, 2023In the Hot Notes: at least 18 people are dead and another 13 injured after shootings in Lewiston Maine; New York Republicans push ahead with a resolution to expel George Santos from the House; NRA revenue is in free-fall after dues and membership plummet; A federal judge has struck down Georgia's congressional and legislative maps ruling that they violate Section 2 of the Voting Rights Act; Ford and the United Auto Workers Union have reached a tentative deal that includes a record pay raise; Republicans delay more than $1B in HIV program funding; a former healthcare executive is charged for a multi-million dollar Medicare fraud scheme; the DoJ responds to Trump's motions to stay his DC gag order and to alert the court of his advice of counsel defense; the US economy grew at a blistering rate in the third quarter; the Ohio secretary of state has quietly removed 26,000 people from voter rolls; plus Allison delivers your Good News.Dana is out and about.More from our Guest:Anna Bowerhttps://twitter.com/annabowerhttps://www.lawfaremedia.orgSubscribe to Lawyers, Guns, And Money:Ad-free premium feed:https://lawyersgunsandmoney.supercast.comSubscribe for free everywhere else:https://link.chtbl.com/LawGunsMoney Our Donation LinksNational Security Counselors - DonateMSW Media, Blue Wave California Victory Fund | ActBlueWhistleblowerAid.org/beansFederal workers - feel free to email AG at fedoath@pm.me and let me know what you're going to do, or just vent. I'm always here to listen. Find Upcoming Actions 50501 Movement, No Kings.org, Indivisible.orgDr. Allison Gill - Substack, BlueSky , TikTok, IG, TwitterDana Goldberg - BlueSky, Twitter, IG, facebook, danagoldberg.comCheck out more from MSW Media - Shows - MSW Media, Cleanup On Aisle 45 pod, The Breakdown | SubstackShare your Good News or Good TroubleMSW Good News and Good TroubleHave some good news; a confession; or a correction to share?Good News & Confessions - The Daily Beanshttps://www.dailybeanspod.com/confessional/ Listener Survey:http://survey.podtrac.com/start-survey.aspx?pubid=BffJOlI7qQcF&ver=shortFollow the Podcast on Apple:The Daily Beans on Apple PodcastsWant to support the show and get it ad-free and early?The Daily Beans | SupercastThe Daily Beans & Mueller, She Wrote | PatreonThe Daily Beans | Apple Podcasts Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

    Creating a Family: Talk about Infertility, Adoption & Foster Care
    Should We Expand Our Special Needs Checklist to Include HIV? - Weekend Wisdom

    Creating a Family: Talk about Infertility, Adoption & Foster Care

    Play Episode Listen Later Oct 25, 2025 12:32 Transcription Available


    Click here to send us a topic idea or question for Weekend Wisdom.Question: My husband and I are considering whether we will open our special needs consideration to include children who are HIV+. We have already been approved to adopt from India, and as our home study update approaches, we are taking a good, hard look at the Special Needs list again. I was listening to your podcast episode on this topic from 2013 and wondered if this was worth an updated episode? Has much changed for families living with HIV?Resources:Factors to Consider When Adopting from IndiaCountry Comparison ChartsCommon Special Needs in International AdoptionSupport the showPlease leave us a rating or review. This podcast is produced by www.CreatingaFamily.org. We are a national non-profit with the mission to strengthen and inspire adoptive, foster & kinship parents and the professionals who support them.Creating a Family brings you the following trauma-informed, expert-based content: Weekly podcasts Weekly articles/blog posts Resource pages on all aspects of family building

    The Naked Scientists Podcast
    Eye implant restores vision, and corvids follow human calls

    The Naked Scientists Podcast

    Play Episode Listen Later Oct 24, 2025 34:44


    In the news podcast, a new retinal implant - just two millimetres wide - that is helping restore sight to blind people; a 'pristine' star that gives us a glimpse of the workings of the early Universe; and we'll be finding out how wild rooks can master human commands. Like this podcast? Please help us by supporting the Naked Scientists

    Horror Queers
    The Orphanage (2007) feat. Shelagh Rowan-Legg

    Horror Queers

    Play Episode Listen Later Oct 22, 2025 120:37


    Don your mask for the treasure hunt because we're discussing J.A. Bayona's The Orphanage (2007) along with Spanish horror scholar (and returning guest) Shelagh Rowan-Legg.Join us as we praise Belén Rueda's lead performance, the film's unsettling set pieces, its curious lack of Spanish cultural signifiers, and speculate on the film's use of HIV in the plot.Plus: the film's obsession with jaws, Joe's suspicions of Carlos' infidelity, and multiple interpretations of the bittersweet ending! Questions? Comments? Snark? Connect with the boys on BlueSky, Instagram, Youtube, Letterboxd, Facebook, or join the Facebook Group or the Horror Queers Discord to get in touch with other listeners.> Trace: @tracedthurman (BlueSky)/ @tracedthurman (Instagram)> Joe: @joelipsett (BlueSky) / @bstolemyremote (Instagram) > Shelagh: @shelaghrowanlegg (BlueSky) / https://shelaghrowanlegg.com/Be sure to support the boys on Patreon!  Theme Music: Alexander Nakarada    Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

    Slate Daily Feed
    3: “A Church with AIDS” | When We All Get to Heaven

    Slate Daily Feed

    Play Episode Listen Later Oct 22, 2025 46:54


    In the late ‘80s, two MCC San Francisco ministers wrote an article called “We Are the Church Alive, the Church with AIDS.” We wanted to know how a gay/lesbian church came to call itself “a church with AIDS.” The answers lie in the years before our audio archive begins. So we started asking people. We explore two stories in what's likely a more complicated shift. One story is about a pair of religion geeks who learned to make queer church in New York during the early years of the AIDS crisis and then came to San Francisco to lead MCCSF. And the other is how an Easter Sunday ritual made the Christian hope of life through death viscerally real. “We Are the Church Alive, the Church with AIDS,” by Kittredge Cherry and Jamies Mitulski was published in the Christian Century on January 27, 1988. For images and links about this episode visit https://www.heavenpodcast.org/episode-3. Get more Outward with Slate Plus! Join for weekly bonus episodes of Outward and ad-free listening on all your favorite Slate podcasts. Subscribe from the Outward show page on Apple Podcasts or Spotify, or visit slate.com/outwardplus for access wherever you listen. Production credits:  When We All Get to Heaven is produced by Eureka Street Productions. It is co-created by Lynne Gerber, Siri Colom, and Ariana Nedelman. Our story editor is Sayre Quevedo. Our sound designer is David Herman. Our managing producer is Krissy Clark. Tim Dillinger is our consulting producer and Betsy Towner Levine is our fact-checker. We had additional story editing help from Sarah Ventre, Arwen Nicks, Allison Behringer, and Krissy Clark. For a complete list of credits, please visit http://heavenpodcast.org/credits. This project received generous support from individual donors, the Henry Luce Foundation (www.hluce.org), the E. Rhodes and Leona B. Carpenter Foundation, and California Humanities, a non-profit partner of the National Endowment for the humanities (www.CalHum.org). Eureka Street Productions has 501c3 status through our fiscal sponsor FJC: A Foundation of Philanthropic Funds. The music for this episode is from the Metropolitan Community Church of San Francisco's archive. It was performed by MCC-SF's musicians and members with Bob Crocker and Jack Hoggatt-St.John as music directors. Additional music is by Tasty Morsels.  “We See You God” is a variation on the anonymously written hymn “We See the Lord.” The soloist in “I Lift Mine Eyes Up” is Bob Crocker. It's by Antonin Dvorak, Biblical Songs, Op. 99, no. 9 on Psalm 121.  “Hush, Hush. Somebody's Calling My Name” is a traditional African American spiritual.  Great thanks, as always, to the members and clergy of the Metropolitan Community Church of San Francisco who made this project possible.   Some links to good groups: The Metropolitan Community Church of San Francisco – the congregation's current website.  Metropolitan Community Churches – the denomination of which MCC San Francisco is a part.  San Francisco AIDS Foundation – a place to seek information about HIV.  POZ Magazine – a place to learn everything else about HIV (information included). Save AIDS Research – their recent, epic 24 hours to Save Research conference with all the latest HIV research is available on YouTube through this site.   LGBTQ Religious Archives Network – the place to get lost in LGBTQ+ religious history. Learn more about your ad choices. Visit megaphone.fm/adchoices

    lemonparty
    156: Statistics to Make You Weep

    lemonparty

    Play Episode Listen Later Oct 21, 2025 79:04


    Ben opines on Akash Singh and the beautiful world of Africa, meanwhile Jace is very upset with HIV transmissions, and Devan basks in the bar culture Sirhan Sirhan once enjoyed in Los Angeles.... this week on lemonparty. bonus episodes ⁠⁠https://www.patreon.com/lemonparty⁠⁠ LP Tour ⁠https://www.lemonparty.life/ ⁠ Support the sponsors: ⁠https://lucy.co/lemon⁠ ⁠https://www.hellofresh.com/lemon10off Learn more about your ad choices. Visit megaphone.fm/adchoices

    Mental Illness Happy Hour
    #770 Imprisoned For Having HIV - Robert Suttle

    Mental Illness Happy Hour

    Play Episode Listen Later Oct 17, 2025 90:12


    Robert Suttle joins Paul to share his experience with the criminalization of HIV. He talks about the unexpected arrest related to his diagnosis, his experience in prison, and living with HIV in the modern day.Links/Resources that Robert mentioned:Elizabeth Taylor AIDS Foundation site: https://elizabethtayloraidsfoundation.org/Elizabeth Taylor AIDS Foundation's HIV is Not a Crime initiative site: https://www.hivisnotacrime-etaf.org/Robert Suttle's site: https://www.robertsuttle.com/ETAF HIV is Not a Crime Roundtable Conversation with Don Lemon (featuring Robert): https://www.youtube.com/watch?v=_cC19N3_IrwVideo spotlight on Robert's story: https://www.youtube.com/watch?v=sw-ZvH-aI9Y This episode is sponsored Quince. Go to www.Quince.com/mental for free shipping on your order and 365-day returns. Now available in Canada, too.This episode is sponsored by NOCD. If you're struggling with OCD or unrelenting intrusive thoughts, NOCD can help. Book a free 15 minute call to get started: https://learn.nocd.com/mentalpodIf you're interested in seeing or buying the furniture that Paul designs and makes follow his IG @ShapedFurniture or visit the website www.shapedfurniture.comWAYS TO HELP THE MIHH PODCASTSubscribe via Apple Podcasts (or whatever player you use). It costs nothing. It's extremely helpful to have your subscription set to download all episodes automatically. https://itunes.apple.com/us/podcast/mental-illness-happy-hour/id427377900?mt=2Spread the word via social media. It costs nothing.Our website is www.mentalpod.com our FB is www.Facebook.com/mentalpod and our Twitter and Instagram are both @Mentalpod Become a much-needed Patreon monthly-donor (with occasional rewards) for as little as $1/month at www.Patreon.com/mentalpod Become a one-time or monthly donor via PayPal at https://mentalpod.com/donateYou can also donate via Zelle (make payment to mentalpod@gmail.com) To donate via Venmo make payment to @Mentalpod See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.