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The FiltrateJoel Topf @kidneyboy.bsky.socialSwapnil Hiremath@hswapnil.medsky.socialAC @medpeedskidneys.bsky.socialSpecial GuestMike Walsh Associate Professor in the Departments of Medicine and Health Research Methods, Evidence, and Impact, McMaster University as well as a Scientist at the Population Health Research Institute and a nephrologist at St. Joseph's Healthcare Hamilton where he is the Chair of the Clinical Nephrology Research Group. Editing and Show Notes bySophia AmbrusoThe Kidney Connection written and performed by Tim YauShow NotesALCHEMIST (NephJC Shorts, Rossignol et al Lancet 2025)AC is in her 83rd year of med-peds fellowship.Joel's monologue brings us all down.Prophylactic ICD therapy doesn't improve sudden cardiac death or all-cause mortality in HD patients in the ICD2 trial (Jukema JW et al. Circulation 2019)Initiation with statins do not impact MACE endpoints or atherosclerotic events (4D AURORA trial Fellstrom BC et al. NEJM 2009 & SHARP trial Baigent C et al. Lancet 2011)Mike tries to liven up the mood by mentioning positive outcomes with iron therapy in heart failure with the PIVOTAL trial (Macdougall IC et al. NEJM 2018)TOPHAT trial revealed treatment with spironolactone in HFpEF did not affect MACE outcomes. (Pitt B et al. NEJM 2014)NephTrials ‘Run-in periods in clinical trials: What can we ACHIEVE?'SPIN D trial - spironolactone dose finding trial in ESRD (Charytan DM et al. Kidney Int 2018)Mike shares the human experience of the trial after being instructed to end the trial prematurely and being told they have “answered their question”Study in Japan - spironolactone predominantly benefits male over females (cannot find this)Male vs female benefit not observed in ACHIEVE despite Mike's initial hypothesisSwap compares and contrasts ACHIEVE, ALCHEMIST & Meta-analysis (Pyne L et al. Lancet 2025)Mike discusses how nonadherence to spironolactone impacted the intention to treat outcomes in the trial.What is a high risk of bias for dummies?Mike, Swap & Joel ponder future nsMRA or ASI trials hemodialysis?Tubular secretionsSwap is probably stalking Martha Wells by now, has moved on from Witch King, now onto Queen Demon on Good ReadsAC is adding to her brood, 2 dogs (Snickers & Harper), 1 childDungeon Crawler Call - a science fantasy book series by Matt Dinniman (on goodreads), which he lovingly referred to as complete nerd trash.Joel is binging on the series Task on HBO max, featuring Mark Ruffalo as FBI agent.NephJC is having its annual fundraiser (get your tickets here) at ASN. Providing a party shuttle that is leaving every 30 minutes from the conference center. As always, it will feature a live podcast recording covering the ASN late breaking, high impact clinical trials.Swap describes the high impact model at ASN this year - go big or go home.
In this flavorful new episode of The Food Professor Podcast—presented by Caddle—Michael LeBlanc and Dr. Sylvain Charlebois serve up an inspiring conversation with Rob Sengotta, chef and co-founder of Von Slick's Finishing Touch, the award-winning Manitoba-based producer of gourmet compound butters.The InterviewRob takes listeners behind the scenes of his chef-to-entrepreneur journey—from fine-dining kitchens in London and France to building a small-batch butter business on the prairies. He shares how curiosity and culinary discipline led to Von Slick's signature push-tube packaging and eight imaginative flavours, including garlic confit, roasted red pepper, mushroom duxelle, and cowboy butter.Listeners learn how Rob and partner Landon Craker turned a spark of an idea into a thriving Western Canadian brand by mastering distribution, leveraging farmers' markets, and staying creative on social media. Rob reflects on his early appearance on Dragon's Den, the lessons learned about timing and valuation, and the advantages of remaining proudly local. He also reveals new restaurant-format products, growing online sales nationwide, and why Canadians' appetite for supporting homegrown brands continues to expand.The NewsIn the first half, Sylvain reports live from Medellín, Colombia, where he's attending an international conference on rural food economies. He offers a fascinating window into Colombia's agricultural transformation—how coffee and cocoa remain vital exports and how farmers are striving to move beyond decades of narcotics-driven instability.Back in Canada, Michael and Sylvain unpack the latest headlines:CFIA factory inspections and the urgent need for transparency;Health Canada's cloned-meat consultations, why silent science can backfire, and the parallels to GMO controversies;Parliamentary hearings on the grocery code of conduct and why supplier–retailer trust still drives price volatility;Bank of Canada's rate decision, its implications for restaurants and food-service recovery; andThere is a growing debate over adopting a U.S.-style SNAP food-assistance program in Canada.This episode blends global perspective, policy insight, and entrepreneurial inspiration—proving again that from farm to fork, the Canadian food economy is as complex as it is delicious. The Food Professor #podcast is presented by Caddle. About UsDr. Sylvain Charlebois is a Professor in food distribution and policy in the Faculties of Management and Agriculture at Dalhousie University in Halifax. He is also the Senior Director of the Agri-food Analytics Lab, also located at Dalhousie University. Before joining Dalhousie, he was affiliated with the University of Guelph's Arrell Food Institute, which he co-founded. Known as “The Food Professor”, his current research interest lies in the broad area of food distribution, security and safety. Google Scholar ranks him as one of the world's most cited scholars in food supply chain management, food value chains and traceability.He has authored five books on global food systems, his most recent one published in 2017 by Wiley-Blackwell entitled “Food Safety, Risk Intelligence and Benchmarking”. He has also published over 500 peer-reviewed journal articles in several academic publications. Furthermore, his research has been featured in several newspapers and media groups, including The Lancet, The Economist, the New York Times, the Boston Globe, the Wall Street Journal, Washington Post, BBC, NBC, ABC, Fox News, Foreign Affairs, the Globe & Mail, the National Post and the Toronto Star.Dr. Charlebois sits on a few company boards, and supports many organizations as a special advisor, including some publicly traded companies. Charlebois is also a member of the Scientific Council of the Business Scientific Institute, based in Luxemburg. Dr. Charlebois is a member of the Global Food Traceability Centre's Advisory Board based in Washington DC, and a member of the National Scientific Committee of the Canadian Food Inspection Agency (CFIA) in Ottawa. Michael LeBlanc is the president and founder of M.E. LeBlanc & Company Inc, a senior retail advisor, keynote speaker and now, media entrepreneur. He has been on the front lines of retail industry change for his entire career. Michael has delivered keynotes, hosted fire-side discussions and participated worldwide in thought leadership panels, most recently on the main stage in Toronto at Retail Council of Canada's Retail Marketing conference with leaders from Walmart & Google. He brings 25+ years of brand/retail/marketing & eCommerce leadership experience with Levi's, Black & Decker, Hudson's Bay, CanWest Media, Pandora Jewellery, The Shopping Channel and Retail Council of Canada to his advisory, speaking and media practice.Michael produces and hosts a network of leading retail trade podcasts, including the award-winning No.1 independent retail industry podcast in America, Remarkable Retail with his partner, Dallas-based best-selling author Steve Dennis; Canada's top retail industry podcast The Voice of Retail and Canada's top food industry and one of the top Canadian-produced management independent podcasts in the country, The Food Professor with Dr. Sylvain Charlebois from Dalhousie University in Halifax.Rethink Retail has recognized Michael as one of the top global retail experts for the fourth year in a row, Thinkers 360 has named him on of the Top 50 global thought leaders in retail, RTIH has named him a top 100 global though leader in retail technology and Coresight Research has named Michael a Retail AI Influencer. If you are a BBQ fan, you can tune into Michael's cooking show, Last Request BBQ, on YouTube, Instagram, X and yes, TikTok.Michael is available for keynote presentations helping retailers, brands and retail industry insiders explaining the current state and future of the retail industry in North America and around the world.
U.N. Secretary General Antonio Guterres has said that global warming will ‘inevitably' surpass 1.5 degrees. What does this mean for global health? The ninth annual Lancet report on health and climate could hold some answers.Also on the program, could contaminated meat be a source for some urinary tract infections? Professor Lance Price speaks about his new study finding a link between the two. Also on the program, could how we walk affect our health more than the distance we've travelled? Health journalist Layal Liverpool joins Claudia Hammond to discuss these stories and more. Presenter: Claudia Hammond with Layal Liverpool Producer: Hannah Robbins and Margaret Sessa-Hawkins with Alice McKee
複雜性創傷後壓力症(complex post-traumatic stress disorder,complex PTSD)在 ICD-11 中被列為「與壓力特別相關的疾病」,它和邊緣型人格障礙症(borderline personality disorder, BDP)是病因相同且相似的疾病,但你知道兩者的核心症狀有何異同嗎?想知道複雜性創傷後壓力症的評估重點以及治療原則又有哪些嗎?
Over the past few months, the stray dog crisis has rocked the country. The numbers are staggering and how to deal with them has elicited multiple, heated opinions. One crucial aspect to this however is rabies: a disease that is completely preventable and yet claims many lives, primarily of children, every year. While the government states that there were 54 human rabies deaths in 2024, a research paper in The Lancet earlier this year put the number at over 5,700 every year. More of concern is cases that have emerged recently – of people dying even after having taken the rabies vaccination.What is the rabies situation in India? Why does the vaccine not work in some cases – are there systemic gaps that need to be addressed? Where does India stand on surveillance of rabies cases, and do dog bites need to be made notifiable? Guest: Dr Subramanian Swaminathan Director of infectious diseases, Glenagles Global Hospital, president, Clinical Infectious Diseases Society of India Host: Zubeda Hamid Edited and produced by Sharmada Venkatasubramanian Learn more about your ad choices. Visit megaphone.fm/adchoices
In this dynamic episode of The Food Professor Podcast, presented by Caddle, co-hosts Michael LeBlanc and Dr. Sylvain Charlebois dive into the latest headlines shaping Canada's food and beverage sector before welcoming Kiran Mann, CEO of Brar's, one of North America's fastest-growing South Asian food manufacturers.The episode opens with a timely look at the hospitality boost from the Toronto Blue Jays' World Series run, a much-needed economic shot in the arm for restaurants and bars coast-to-coast. From there, Sylvain unpacks fresh Canadian inflation data, connecting global trade policy, tariffs, and drought-driven beef shortages to continued food-price volatility. He explains why Canadian beef prices will likely remain high until mid-2027, and how regional differences—from Saskatchewan's 5.5 percent food inflation to Ontario's 3.5 percent—highlight a widening national divide. The conversation also tackles layoffs at Molson Coors and Nestlé, changing consumer habits amid the Ozempic effect, and why Big CPG must reinvent itself as Canadians buy more locally produced goods. The duo rounds out the news rundown with an update on Agropur's cottage-cheese lockout and a surprising salmonella outbreak in dog treats, underscoring the need for better pet-food safety oversight.Then, Michael and Sylvain welcome Kiran Mann, an inspirational immigrant entrepreneur and visionary leader steering Brar's from family-run origins to a national and expanding international powerhouse. Mann shares her remarkable journey—from her roots in Amritsar, India, to leading a modern Canadian company that connects authentic Indian flavours with contemporary manufacturing innovation. She explains Brar's evolution across three categories—dairy, snacks, and sweets—including its beloved samosas, signature paneer, and pure-vegetarian veggie burgers.Mann introduces her proprietary “Harmonic System”—a leadership and operational philosophy grounded in balance, authenticity, and purpose. Her approach integrates people, process, and passion, ensuring that growth doesn't outpace culture or quality. The discussion explores how Brar's sustains traditional recipes while using food science to extend shelf life naturally, create sustainable packaging, and meet the needs of health-conscious, multicultural consumers. Looking ahead, Mann outlines her strategy of “depth and impact,” combining Canadian multiculturalism, sustainable supply chains, and bold U.S. expansion to make Brar's a global ambassador of modern Indian cuisine made in Canada. The Food Professor #podcast is presented by Caddle. About UsDr. Sylvain Charlebois is a Professor in food distribution and policy in the Faculties of Management and Agriculture at Dalhousie University in Halifax. He is also the Senior Director of the Agri-food Analytics Lab, also located at Dalhousie University. Before joining Dalhousie, he was affiliated with the University of Guelph's Arrell Food Institute, which he co-founded. Known as “The Food Professor”, his current research interest lies in the broad area of food distribution, security and safety. Google Scholar ranks him as one of the world's most cited scholars in food supply chain management, food value chains and traceability.He has authored five books on global food systems, his most recent one published in 2017 by Wiley-Blackwell entitled “Food Safety, Risk Intelligence and Benchmarking”. He has also published over 500 peer-reviewed journal articles in several academic publications. Furthermore, his research has been featured in several newspapers and media groups, including The Lancet, The Economist, the New York Times, the Boston Globe, the Wall Street Journal, Washington Post, BBC, NBC, ABC, Fox News, Foreign Affairs, the Globe & Mail, the National Post and the Toronto Star.Dr. Charlebois sits on a few company boards, and supports many organizations as a special advisor, including some publicly traded companies. Charlebois is also a member of the Scientific Council of the Business Scientific Institute, based in Luxemburg. Dr. Charlebois is a member of the Global Food Traceability Centre's Advisory Board based in Washington DC, and a member of the National Scientific Committee of the Canadian Food Inspection Agency (CFIA) in Ottawa. Michael LeBlanc is the president and founder of M.E. LeBlanc & Company Inc, a senior retail advisor, keynote speaker and now, media entrepreneur. He has been on the front lines of retail industry change for his entire career. Michael has delivered keynotes, hosted fire-side discussions and participated worldwide in thought leadership panels, most recently on the main stage in Toronto at Retail Council of Canada's Retail Marketing conference with leaders from Walmart & Google. He brings 25+ years of brand/retail/marketing & eCommerce leadership experience with Levi's, Black & Decker, Hudson's Bay, CanWest Media, Pandora Jewellery, The Shopping Channel and Retail Council of Canada to his advisory, speaking and media practice.Michael produces and hosts a network of leading retail trade podcasts, including the award-winning No.1 independent retail industry podcast in America, Remarkable Retail with his partner, Dallas-based best-selling author Steve Dennis; Canada's top retail industry podcast The Voice of Retail and Canada's top food industry and one of the top Canadian-produced management independent podcasts in the country, The Food Professor with Dr. Sylvain Charlebois from Dalhousie University in Halifax.Rethink Retail has recognized Michael as one of the top global retail experts for the fourth year in a row, Thinkers 360 has named him on of the Top 50 global thought leaders in retail, RTIH has named him a top 100 global though leader in retail technology and Coresight Research has named Michael a Retail AI Influencer. If you are a BBQ fan, you can tune into Michael's cooking show, Last Request BBQ, on YouTube, Instagram, X and yes, TikTok.Michael is available for keynote presentations helping retailers, brands and retail industry insiders explaining the current state and future of the retail industry in North America and around the world.
New research has confirmed Ozempic reduces the risk of strokes and heart attacks by 20 percent - even in patients who weren't severely overweight to start with. The study, which was led by University College London and published in The Lancet, found that weight loss accounted for only one third of this reduction. Auckland University molecular medicine professor Peter Shepherd says this is proof other factors are behind the slowdown of heart disease. "We know a few of them, we know a bit about how it effects heart tissue growth, we know a bit about the positive effects it has on the deposition of the lipids, but there's still a long way to go to fully understand its effects." LISTEN ABOVESee omnystudio.com/listener for privacy information.
D'après une récente étude publiée dans la revue médicale The Lancet, la France aurait le taux de cancer le plus élevé au monde après Monaco. Un classement inquiétant qui a fait couler beaucoup d'encre dans les médias français. Mais comment l'expliquer ? Est-ce à cause du mode de vie des Français, de facteurs environnementaux, ou simplement parce que leur système de santé détecte mieux les cancers ? Dans cet épisode, Hugo explore les raisons de ce phénomène. Il explique aussi pourquoi, malgré ces chiffres alarmants, les taux de survie restent parmi les meilleurs d'Europe. Enfin, il évoque les défis du système de santé français et l'importance cruciale du dépistage. Un sujet préoccupant... mais pas sans espoir ! Retrouvez la transcription de l'épisode sur www.innerfrench.com/e182 Retrouvez nos cours pour améliorez votre français sur www.courses.innerfrench.com
Dr. Dipen J. Parekh is a globally renowned urologic oncologist, healthcare innovator, and leader in academic medicine. He was appointed Executive Vice President for Health Affairs at the University of Miami and Chief Executive Officer of its health system (UHealth) on June 1, 2025. He remains Founding Director of the Desai Sethi Urology Institute and is an accomplished researcher and professor at the University of Miami Miller School of Medicine who holds the Victor A. Politano Endowed Chair in Urology and is widely celebrated for his groundbreaking contributions to the field of robotic-assisted urologic oncology. Having served as Chief Operating Officer of UHealth from 2020-2025, Chief Clinical Officer from 2017-2020, Chairman of the Department of Urology since 2012, Executive Dean of Clinical Affairs at the University of Miami Miller School of Medicine, and Director of Robotic Surgery for UHealth, Dr. Parekh brings a wealth of academic, clinical, administrative, and institutional experience to the role.Over the course of his career, Dr. Parekh has performed more than 6,000 robotic urologic cancer surgeries, making him one of the most experienced practitioners worldwide. He led the groundbreaking RAZOR trial, published in The Lancet in 2018, which established the efficacy of robotic-assisted radical cystectomy as comparable to open surgery for bladder cancer. He is an NCI funded surgeon scientist with over 200 peer reviewed publications in urologic oncology. His dedication to innovation has also included establishing advanced robotic surgery programs in academic centers across the globe.
Rethinking Diabetes: 7 Eye-Opening Truths Every Woman Should Knowhttps://rawfoodmealplanner.com/rethinking-diabetes-7-eye-opening-truths-every-woman-should-know/Boost Your Wellness Journey:The Brain Reboot Plan: 5 Simple Daily Shifts for More Focus, Energy & Peacehttps://rawfoodmealplanner.com/brain-reboot-plan/Revitalize Your Brain: A Lifestyle Approach for Women Over 50https://rawfoodmealplanner.clickfunnels.com/webinar-replay-brain-health-breakthrough-coaching-programRESET: 3 Metabolic Mistakes Women 30+ Make And How to Fix Themhttps://rawfoodmealplanner.com/reset-3-metabolic-mistakes-women-30-make-and-how-to-fix-them/The Lancet published a study here https://www.thelancet.com/journals/lanhl/article/PIIS2666-7568(24)00191-0/fulltext emphasizing that young adults (ages 18–39) are a neglected but crucial window for dementia prevention. Most dementia research focuses on mid-to-late life, yet many modifiable risk factors that affect long-term brain health emerge or peak in young adulthood.Key Modifiable Risk FactorsEducation: Low levels reduce cognitive reserve and increase dementia risk.Hearing loss: One billion young adults globally are at risk due to unsafe listening practices.Traumatic brain injury (TBI): High rates from sports, motor accidents, and intimate partner violence.Hypertension: One in 12 young adults is affected; rates higher among Black Americans and in LMICs.Alcohol use: Peaks in early 20s, linked to long-term brain changes.Obesity & physical inactivity: Both rising rapidly; linked to inflammation and cardiovascular risk.Smoking/vaping: 90% of daily smokers start before 26.Depression & social isolation: Peak in early 20s, linked to later ADRD (Alzheimer's disease and related dementias) risk.Diabetes: 4% prevalence in young adults; prediabetes affects 1 in 4.Environmental factors: Air pollution, vision loss, high LDL cholesterol, and even emerging risks like sleep disruption, stress, spirituality, and microplastics.Join the Conversation:Subscribe and share this episode with anyone on their own path of health and transformation. // HOST Samantha Salmon, NBC-HWC Nationally Board Certified Health & Wellness CoachBrain Health Licensed TrainerIntegrative Nutrition CoachIntuitive Eating CoachThe information provided in this broadcast is for educational purposes only and is not intended as medical advice. These statements have not been evaluated by the Food and Drug Administration or the equivalent in your country. Any products/services mentioned are not intended to diagnose, treat, cure, or prevent disease. RawFoodMealPlanner.com © 2025
In this special series on The Cardiovascular Outcome Trials our host, Dr. Neil Skolnik will discuss the history and importance of the Cardiovascular Outcome Trials for diabetes medications . In Part 1 we discuss an historical perspective with Dr. Steven Nissan and how this has lead to the CVOTs that change the way we practice from EMPA-REG in 2015 to SURPASS-CVOT in 2025. This special episode is supported by an independent educational grant from Lilly. Presented by: Neil Skolnik, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington Jefferson Health Steven Nissen, M.D., Chief Academic Officer of the Heart and Vascular Institute at the Cleveland Clinic and Professor of Medicine at the Clevland Clinic Lerner College of Medicine. Selected references: Nissen SE, Wolski K, Topol EJ. Effect of Muraglitazar on Death and Major Adverse Cardiovascular Events in Patients With Type 2 Diabetes Mellitus. JAMA. 2005;294:2581-2586 Kahn SE, Haffner SM, Heise MA, et al. Glycemic Durability of Rosiglitazone, Metformin, or Glyburide Monotherapy (ADOPT). N Engl J Med 2006;355:242743. DREAM trial investigators. Effect of rosiglitazone on the frequency of diabetes in patients with impaired glucose tolerance or impaired fasting glucose: a randomised controlled trial. Lancet 2006;368:1096 Nissen SE, Wolski K. Effect of Rosiglitazone on the Risk of Myocardial Infarction and Death from Cardiovascular Causes. N Engl J Med 2007;356:2457-2471.
In patients with heart failure, remote hemodynamic monitoring can identify health changes long before symptoms appear, contributing to slower disease progression, improved patient outcomes, and reduced rehospitalizations. Learn more about current and future technology that can support better patient health, and the role of nurses in patient education and monitoring. Guests: Linda Park, PhD, MS, FNP-BC, FAAN, FAHA, FPCNA, and Eryn Bryant, MSN, APRN-CNP, FPCNA.PCNA Heart Failure Tools: https://pcna.net/health-topics/heart-failure/Tele-HF study: https://www.jacc.org/doi/10.1016/j.jchf.2015.07.017 CHAMPION Trial (CMEMs after CRT): Pulmonary Artery Pressure-Guided Management of Patients With Heart Failure and Reduced Ejection Fraction https://www.acc.org/latest-in-cardiology/clinical-trials/2015/12/29/12/44/championJournal of American College of Cardiology paper, Remote Monitoring and Heart Failure Scientific Statement: https://www.jacc.org/doi/10.1016/j.jacc.2023.04.010 European Society of Cardiology consensus statement: https://doi.org/10.1093/eurheartjsupp/suae116BMAD trial: BMAD Trial: Wearable Remote Monitor Reduces Hospital Readmission Risk in HF Patients - American College of Cardiology: https://www.acc.org/Latest-in-Cardiology/Articles/2023/03/01/22/45/mon-830am-bmad-acc-2023 GUIDE-HF trial (CMEMS, Lancet): Haemodynamic-guided management of heart failure (GUIDE-HF): a randomised controlled trial - The Lancet: https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(21)01754-2/abstractESCAPE trial (using RHC / pulm art pressures to guide therapy during ADHF: Evaluation study of congestive heart failure and pulmonary artery catheterization effectiveness: the ESCAPE trial - PubMed: https://pubmed.ncbi.nlm.nih.gov/16204662/MONITOR-HF trial (improved QOL and functional status w/ CMEMs): Remote haemodynamic monitoring of pulmonary artery pressures in patients with chronic heart failure (MONITOR-HF): a randomised clinical trial - The Lancet: https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(23)00923-6/abstract MONITOR-HF: Pulmonary artery pressure monitoring in chronic heart failure: effects across clinically relevant subgroups in the MONITOR-HF trial | European Heart Journal | Oxford Academic: https://academic.oup.com/eurheartj/article/45/32/2954/7668040MONITOR-HF (summary in ACC): Remote Hemodynamic Monitoring of Pulmonary Artery Pressures in Patients With Chronic Heart Failure - American College of Cardiology: https://www.acc.org/Latest-in-Cardiology/Clinical-Trials/2023/07/18/17/21/monitor-hfHeartLogic: HeartLogic Multisensor Algorithm Identifies Patients During Periods of Significantly Increased Risk of Heart Failure Events: https://www.ahajournals.org/doi/10.1161/CIRCHEARTFAILURE.117.004669SCALE-HF-1 Trial (bodyport scale to predict worsening HF trends): Use of a Cardiac Scale to Predict Heart Failure Events: Design of SCALE-HF 1 | Circulation: Heart Failure: https://www.ahajournals.org/doi/10.1161/CIRCHEARTFAILURE.122.010012See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Un nouvel épisode du Pharmascope est disponible! Dans ce 165e épisode, Nicolas, Isabelle et Olivier discutent d'un sujet douloureux… La migraine! Dans cette dernière partie d'une série de trois épisodes, nous abordons la migraine chronique et la céphalée par abus médicamenteux Les objectifs pour cet épisode sont les suivants: Discuter de l'évaluation et du diagnostic de la migraine chronique et de la céphalée médicamenteuse Discuter de la prise en charge de la migraine chronique Discuter de la prise en charge de la céphalée d'abus médicamenteux Ressources pertinentes en lien avec l'épisode Ashina M. Migraine. N Engl J Med. 2020;383(19):1866-1876. Medrea I et coll. Updated Canadian Headache Society Migraine Prevention Guideline with Systematic Review and Meta-analysis. Can J Neurol Sci. 2024 Nov 7:1-23. Pozo-Rosich P et coll. Atogepant for the preventive treatment of chronic migraine (PROGRESS): a randomised, double-blind, placebo-controlled, phase 3 trial. Lancet. 2023 Sep 2;402(10404):775-785. Chowdhury D et coll. TOP-PRO study: A randomized double-blind controlled trial of topiramate versus propranolol for prevention of chronic migraine. Cephalalgia. 2022 Apr;42(4-5):396-408. Dodick DW et coll.; PREEMPT Chronic Migraine Study Group. OnabotulinumtoxinA for treatment of chronic migraine: pooled results from the double-blind, randomized, placebo-controlled phases of the PREEMPT clinical program. Headache. 2010 Jun;50(6):921-36. Ashina S et coll. Medication overuse headache. Nat Rev Dis Primers. 2023 Feb 2;9(1):5. Rossi P et coll. Advice alone vs. structured detoxification programmes for medication overuse headache: a prospective, randomized, open-label trial in transformed migraine patients with low medical needs. Cephalalgia. 2006 Sep;26(9):1097-105. Hagen K et coll. Management of medication overuse headache: 1-year randomized multicentre open-label trial. Cephalalgia. 2009 Feb;29(2):221-32. Carlsen LN et coll. Comparison of 3 Treatment Strategies for Medication Overuse Headache: A Randomized Clinical Trial. JAMA Neurol. 2020 Sep 1;77(9):1069-1078. Tepper SJ et coll. Efficacy and Safety of Erenumab for Nonopioid Medication Overuse Headache in Chronic Migraine: A Phase 4, Randomized, Placebo-Controlled Trial. JAMA Neurol. 2024 Sep 16;81(11):1140-9. de Goffau MJ, Klaver ARE, Willemsen MG, Bindels PJE, Verhagen AP. The Effectiveness of Treatments for Patients With Medication Overuse Headache: A Systematic Review and Meta-Analysis. J Pain. 2017 Jun;18(6):615-627. Grazzi L et coll. Efficacy of mindfulness added to treatment as usual in patients with chronic migraine and medication overuse headache: a phase-III single-blind randomized-controlled trial (the MIND-CM study). J Headache Pain. 2023 Jul 14;24(1):86.
Shun Lu joins Ben Abbott of The Lancet to discuss the phase 3 HARMONi-6 trial of ivonescimab plus chemotherapy as first-line treatment in advanced squamous non-small-cell lung cancer, which is being presented at ESMO 2025.Click here to read the full articleContinue this conversation on social!Follow us today at...https://thelancet.bsky.social/https://instagram.com/thelancetgrouphttps://facebook.com/thelancetmedicaljournalhttps://linkedIn.com/company/the-lancethttps://youtube.com/thelancettv
In this WKC Spill The Tea episode, we're joined by the extraordinary Fiona Clark, award-winning journalist, women's health advocate, and author of MenoWars. Fiona brings fire, humour and expertise to the menopause landscape which has become muddied with commercialism and mis-information. Fiona's career spans continents and causes- from reporting in Moscow on the collapse of the Soviet Union, to writing for The Lancet, and now to tackling menopause- one of the most misunderstood and politicised topics in women's health.We chat about:
Gavin is joined once again by Richard and Jessamy as they examine key developments in global health and science.This week's discussion features reflections on the launch of a new Lancet series on Alzheimer's disease, highlighting advances in prevention, diagnosis, and care, as well as the ethical and practical challenges posed by emerging treatments.We also explore the global landscape of liver cancer, demographic change, the shifting centre of scientific research, and recent studies on human longevity. Join us for a thoughtful, evidence-based conversation on pressing issues in health, policy, and research worldwide.Read the full series: https://www.thelancet.com/series-do/alzheimers-diseaseRead the full commission: https://www.thelancet.com/commissions-do/hepatocellular-carcinomaSend us your feedback!Read all of our content at https://www.thelancet.com/?dgcid=buzzsprout_tlv_podcast_generic_lancetCheck out all the podcasts from The Lancet Group:https://www.thelancet.com/multimedia/podcasts?dgcid=buzzsprout_tlv_podcast_generic_lancetContinue this conversation on social!Follow us today at...https://thelancet.bsky.social/https://instagram.com/thelancetgrouphttps://facebook.com/thelancetmedicaljournalhttps://linkedIn.com/company/the-lancethttps://youtube.com/thelancettv
In this episode of The Food Professor Podcast, presented by Caddle, co-hosts Michael LeBlanc and Dr. Sylvain Charlebois open with a wide-ranging conversation on global trade tensions, the state of Canadian agriculture, and the latest policy moves shaping our food economy — before turning to the fascinating story of Stephen Mitchell, President of Sprucewood Shores Estate Winery, Ontario's only beachfront winery on the Lake Erie North Shore.Michael and Sylvain begin by unpacking the economic aftershocks of U.S. tariff wars, as soybean farmers in America face devastating losses and look for government bailouts amid shifting Chinese trade alliances. Sylvain, speaking from Purdue University in Indiana, shares first-hand insights from conversations with American farmers reeling from collapsed exports and rising equipment costs. The hosts then pivot to the EV tariff dispute between Canada, China, and the U.S., discussing whether Ottawa should drop tariffs on Chinese electric vehicles to save Canadian canola farmers — a debate intensified by security concerns and diplomatic pressures. They also explore evolving Canada–India trade relations, the potential of government-run grocery stores, and Canada's climb to #7 in the Global Agri-Food Most Influential Nations report released on World Food Day, produced in partnership with MNP.Then, Michael introduces Stephen Mitchell for a compelling look at the business of craft wine in Ontario. Stephen recounts the family story behind Sprucewood Shores — from his father's dream of returning to his farming roots to the hands-on creation of a 52-acre lakeside vineyard and winery. He describes how the business evolved from a weekend “hobby farm” into a major local producer, now recognized for its Beach Glass Series, Classic Series, and signature Warm & Cozy mulled wine, distributed through the LCBO and beyond. Stephen details how the winery balances tradition with innovation — focusing on approachability, sustainability, and product diversification — while investing to capture new market momentum as Ontario's wine industry gains visibility and political support. He also shares marketing lessons learned through social media, tastings, and direct-to-consumer engagement, underscoring that success in wine is about constant connection and storytelling.Link Global Agri-Food Most Influential Nations interactive site and report released on World Food Day, produced in partnership with MNPhttps://www.mnp.ca/en/clients/food-and-beverage-processing/momentum-is-building-canadas-rise-in-global-agri-food#reportLink to Whole Foods trends report 2026https://www.freshfruitportal.com/news/2025/10/13/whole-foods-trends-2026/. The Food Professor #podcast is presented by Caddle. About UsDr. Sylvain Charlebois is a Professor in food distribution and policy in the Faculties of Management and Agriculture at Dalhousie University in Halifax. He is also the Senior Director of the Agri-food Analytics Lab, also located at Dalhousie University. Before joining Dalhousie, he was affiliated with the University of Guelph's Arrell Food Institute, which he co-founded. Known as “The Food Professor”, his current research interest lies in the broad area of food distribution, security and safety. Google Scholar ranks him as one of the world's most cited scholars in food supply chain management, food value chains and traceability.He has authored five books on global food systems, his most recent one published in 2017 by Wiley-Blackwell entitled “Food Safety, Risk Intelligence and Benchmarking”. He has also published over 500 peer-reviewed journal articles in several academic publications. Furthermore, his research has been featured in several newspapers and media groups, including The Lancet, The Economist, the New York Times, the Boston Globe, the Wall Street Journal, Washington Post, BBC, NBC, ABC, Fox News, Foreign Affairs, the Globe & Mail, the National Post and the Toronto Star.Dr. Charlebois sits on a few company boards, and supports many organizations as a special advisor, including some publicly traded companies. Charlebois is also a member of the Scientific Council of the Business Scientific Institute, based in Luxemburg. Dr. Charlebois is a member of the Global Food Traceability Centre's Advisory Board based in Washington DC, and a member of the National Scientific Committee of the Canadian Food Inspection Agency (CFIA) in Ottawa. Michael LeBlanc is the president and founder of M.E. LeBlanc & Company Inc, a senior retail advisor, keynote speaker and now, media entrepreneur. He has been on the front lines of retail industry change for his entire career. Michael has delivered keynotes, hosted fire-side discussions and participated worldwide in thought leadership panels, most recently on the main stage in Toronto at Retail Council of Canada's Retail Marketing conference with leaders from Walmart & Google. He brings 25+ years of brand/retail/marketing & eCommerce leadership experience with Levi's, Black & Decker, Hudson's Bay, CanWest Media, Pandora Jewellery, The Shopping Channel and Retail Council of Canada to his advisory, speaking and media practice.Michael produces and hosts a network of leading retail trade podcasts, including the award-winning No.1 independent retail industry podcast in America, Remarkable Retail with his partner, Dallas-based best-selling author Steve Dennis; Canada's top retail industry podcast The Voice of Retail and Canada's top food industry and one of the top Canadian-produced management independent podcasts in the country, The Food Professor with Dr. Sylvain Charlebois from Dalhousie University in Halifax.Rethink Retail has recognized Michael as one of the top global retail experts for the fourth year in a row, Thinkers 360 has named him on of the Top 50 global thought leaders in retail, RTIH has named him a top 100 global though leader in retail technology and Coresight Research has named Michael a Retail AI Influencer. If you are a BBQ fan, you can tune into Michael's cooking show, Last Request BBQ, on YouTube, Instagram, X and yes, TikTok.Michael is available for keynote presentations helping retailers, brands and retail industry insiders explaining the current state and future of the retail industry in North America and around the world.
Daniel Månsson is a clinical psychologist and co-founder of Flow Neuroscience, a medical device comapny which produces transcranial direct current stimulation (TDCS) headsets for depression. Today we discuss: What may be happening neurologically in certain cases of depressionDifferent research studies that have looked into the effectiveness of TDCS treatment for depressionThe ethical challenges of studying, producing and selling medical devicesHow these devices may complement psychological treatments like psychotherapy Studies mentioned:Transcranial direct current stimulation as an additional treatment to selective serotonin reuptake inhibitors in adults with major depressive disorder in Germany (DepressionDC): a triple-blind, randomised, sham-controlled, multicentre trial - The Lancet - https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(23)00640-2/abstractHome-based transcranial direct current stimulation treatment for major depressive disorder: a fully remote phase 2 randomized sham-controlled trial | Nature Medicine - https://www.nature.com/articles/s41591-024-03305-yHome-Use Transcranial Direct Current Stimulation for the Treatment of a Major Depressive Episode: A Randomized Clinical Trial | Depressive Disorders | JAMA Psychiatry | JAMA Network https://jamanetwork.com/journals/jamapsychiatry/fullarticle/2813623Northamptonshire NHS study:https://www.scirp.org/journal/paperinformation?paperid=131358--------------------------------------------------------------------------------------------------------------Interviewed by Dr. Alex Curmi with Dr. Anya Borissova. Dr. Alex is a consultant psychiatrist and a UKCP registered psychotherapist in-training. Dr. Anya is a academic registrar psychiatrist at the South London and Maudsley trust. If you would like to invite Alex to speak at your organisation please email alexcurmitherapy@gmail.com with "Speaking Enquiry" in the subject line.Alex is not currently taking on new psychotherapy clients, if you are interested in working with Alex for focused behaviour change coaching , you can email - alexcurmitherapy@gmail.com with "Coaching" in the subject line.Check out The Thinking Mind Blog on Substack: https://substack.com/home/post/p-174371597Give feedback here - thinkingmindpodcast@gmail.com Follow us here: Twitter @thinkingmindpod Instagram @thinkingmindpodcast
In this powerful new episode of The Food Professor Podcast, presented by Caddle, co-hosts Michael LeBlanc and Dr. Sylvain Charlebois dissect the forces shaping Canada's food and agriculture economy—from farmland bubbles and provincial politics to the latest retail coffee price increases.The show opens with Michael's visit to Prince Edward County, where he talks about reconnecting with past guest Dan Sullivan of Rosehall Run Vineyards and celebrates the growing influence of culinary innovator and recent guest Charlotte Langley, whose tinned-seafood brand Nice Cans is redefining Canadian bespoke tinned fish dining. Sylvain weighs in on stalled interprovincial trade and Premier Doug Ford's ongoing feud with Crown Royal and Diageo, exploring the politics of booze, bans, and consumer choice - and his support of ice cream maker Chapman's. The hosts also spotlight the wild-blueberry disaster in Atlantic Canada, where drought and fires have slashed yields by up to 70%, threatening regional processors and exports.Then the conversation shifts to a fascinating—and controversial—guest: Trent Klarenbach, BSA AgEc PAg, Special Crops & Grain Marketing Analyst and Founder of Klarenbach Research. A former Saskatchewan farmer turned analyst, Trent explains how he uses technical analysis—tools typically reserved for stock markets—to assess farmland value. His research suggests land in Saskatchewan and Alberta may be overbought, echoing warning signs that preceded the dramatic farmland correction of the 1980s.Trent describes how investor psychology and market cycles shape agriculture just as they do equities, applying RSI and Elliott Wave patterns to farmland data. He details his own journey through farming's booms and busts, his motivation for building a subscription-based insights service, and the mixed reactions he's received from farmers, lenders, and ag-finance professionals. For listeners seeking deeper understanding of the economics—and emotion—behind land ownership, his approach reframes how to think about farm equity and risk.The episode wraps with Michael and Sylvain analyzing temporary-foreign-worker fines, Tim Hortons' price move and Starbucks store closures, and Donald Trump's revived talk of U.S. dairy access. They close on a high note—what soaring bullion signals about global uncertainty and food-price volatility.Website: https://www.klarenbach.ca/YouTube:https://www.youtube.com/@KlarenbachResearchPodcast:https://youtube.com/playlist?list=PL28YhqW-kvxkfu1I6xFdtaa5BN1GVoHxa&si=_iVqyKVYCkfm6S1m The Food Professor #podcast is presented by Caddle. About UsDr. Sylvain Charlebois is a Professor in food distribution and policy in the Faculties of Management and Agriculture at Dalhousie University in Halifax. He is also the Senior Director of the Agri-food Analytics Lab, also located at Dalhousie University. Before joining Dalhousie, he was affiliated with the University of Guelph's Arrell Food Institute, which he co-founded. Known as “The Food Professor”, his current research interest lies in the broad area of food distribution, security and safety. Google Scholar ranks him as one of the world's most cited scholars in food supply chain management, food value chains and traceability.He has authored five books on global food systems, his most recent one published in 2017 by Wiley-Blackwell entitled “Food Safety, Risk Intelligence and Benchmarking”. He has also published over 500 peer-reviewed journal articles in several academic publications. Furthermore, his research has been featured in several newspapers and media groups, including The Lancet, The Economist, the New York Times, the Boston Globe, the Wall Street Journal, Washington Post, BBC, NBC, ABC, Fox News, Foreign Affairs, the Globe & Mail, the National Post and the Toronto Star.Dr. Charlebois sits on a few company boards, and supports many organizations as a special advisor, including some publicly traded companies. Charlebois is also a member of the Scientific Council of the Business Scientific Institute, based in Luxemburg. Dr. Charlebois is a member of the Global Food Traceability Centre's Advisory Board based in Washington DC, and a member of the National Scientific Committee of the Canadian Food Inspection Agency (CFIA) in Ottawa. Michael LeBlanc is the president and founder of M.E. LeBlanc & Company Inc, a senior retail advisor, keynote speaker and now, media entrepreneur. He has been on the front lines of retail industry change for his entire career. Michael has delivered keynotes, hosted fire-side discussions and participated worldwide in thought leadership panels, most recently on the main stage in Toronto at Retail Council of Canada's Retail Marketing conference with leaders from Walmart & Google. He brings 25+ years of brand/retail/marketing & eCommerce leadership experience with Levi's, Black & Decker, Hudson's Bay, CanWest Media, Pandora Jewellery, The Shopping Channel and Retail Council of Canada to his advisory, speaking and media practice.Michael produces and hosts a network of leading retail trade podcasts, including the award-winning No.1 independent retail industry podcast in America, Remarkable Retail with his partner, Dallas-based best-selling author Steve Dennis; Canada's top retail industry podcast The Voice of Retail and Canada's top food industry and one of the top Canadian-produced management independent podcasts in the country, The Food Professor with Dr. Sylvain Charlebois from Dalhousie University in Halifax.Rethink Retail has recognized Michael as one of the top global retail experts for the fourth year in a row, Thinkers 360 has named him on of the Top 50 global thought leaders in retail, RTIH has named him a top 100 global though leader in retail technology and Coresight Research has named Michael a Retail AI Influencer. If you are a BBQ fan, you can tune into Michael's cooking show, Last Request BBQ, on YouTube, Instagram, X and yes, TikTok.Michael is available for keynote presentations helping retailers, brands and retail industry insiders explaining the current state and future of the retail industry in North America and around the world.
Wes, Eneasz, and David keep the rationalist community informed about what's going on outside of the rationalist communitySupport us on Substack!News links:Youtube is the latest company to give Trump a payoffHegseth sent 200 national guard troops to PortlandE.J. Antoni nomination to BLS withdrawnHHS said it is referring Harvard for suspension and debarment proceedings.Trump defunding the ethics watchdogspaused $2.1B in federal funds for Chicago infrastructure projectsTrump made an Israel-Hamas peace plan?James Comey indictedTrumpRX is apparently going to be a thingFederal Judge: Trump Administration violated 1A by deporting Palestinian sympathizersHegseth called in all the generals to tell them they're too fatTrump apparently all-in on support for Ukraine.EA bought out by (among others) the Saudi Public Investment CorporationHappy News!San Fran Supervisor going YIMBY on business regulationsJames Web Space Telescope is now examining the atmospheric make-up of exoplanets!Denver's Support Team Assistance Response (STAR) program is working!city reports 45% decrease in street peopleRecent study in Lancet shows people dying from chronic diseases globally fell in four out of five nations between 2010 and 2019The 60th nation ratified the High Seas Treaty, meaning it'll soon become legally bindingChina has signed on to this one and a related treaty20% increase in kids getting school lunches in last five years, worldwideHuntington disease treated for the first time!Got something to say? Come chat with us on the Bayesian Conspiracy Discord or email us at themindkillerpodcast@gmail.com. Say something smart and we'll mention you on the next show!Follow us!RSS: http://feeds.feedburner.com/themindkillerGoogle: https://play.google.com/music/listen#/ps/Iqs7r7t6cdxw465zdulvwikhekmPocket Casts: https://pca.st/vvcmifu6Stitcher: https://www.stitcher.com/podcast/the-mind-killerApple: Intro/outro music: On Sale by Golden Duck Orchestra This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit mindkiller.substack.com/subscribe
In July 2023, the ACOG released a Practice Advisory stating, “Based on data on the benefit of adjunct HPV vaccination, ACOG recommends adherence to the current Centers for Disease Control and Prevention (CDC) recommendations for vaccinations of individuals aged 9–26 years, and to consider adjuvant HPV vaccination for immunocompetent previously unvaccinated people aged 27–45 years who are undergoing treatment for CIN 2+”. The possible beneficial effect of peri-treatment HPV vaccination goes back to the early 2010s. But science is always changing, and MEDICINE MOVES FAST. In September 2025, the Lancet's Obstetrics, Gynecology, and Women's Health journal published the VACCIN trial to test that guidance. These authors found that, “Although previous studies, including meta-analyses and observational studies, have shown that adjuvant HPV vaccination reduces the recurrence of cervical dysplasia after surgical treatment, our trial suggests that adjuvant HPV vaccination is not effective in reducing the recurrence of CIN 2–3 lesions, contradicting the conclusions of previous works”. They have also called for a REVISION to prior guidance. This is FASCINATING. Listen in for details. 1. ACOG PA July 2023, “Adjuvant Human Papillomavirus Vaccination for Patients Undergoing Treatment for Cervical Intraepithelial Neoplasia 2+”2. Adjuvant prophylactic human papillomavirus vaccination for prevention of recurrent high-grade cervical intraepithelial neoplasia lesions in women undergoing lesion surgical treatment (VACCIN): a multicentre, phase 4 randomised placebo-controlled trial in the Netherlands: https://www.sciencedirect.com/science/article/pii/S305050382500007X#:~:text=To%20our%20knowledge%2C%20this%20is,the%20conclusions%20of%20previous%20works.STRONG COFFEE PROMO: 20% Off Strong Coffee Company https://strongcoffeecompany.com/discount/CHAPANOSPINOBG
Join the Behind the Knife Surgical Oncology Team as we discuss the nuances in the work up and management of patients with pheochromocytomas. Hosts: Timothy Vreeland, MD, FACS (@vreelant) is an Assistant Professor of Surgery at the Uniformed Services University of the Health Sciences and Surgical Oncologist at Brooke Army Medical Center. Daniel Nelson, DO, FACS (@usarmydoc24) is Surgical Oncologist/HPB surgeon at Kaiser LAMC in Los Angeles. Lexy (Alexandra) Adams, MD, MPH (@lexyadams16) is a 2ndYear Surgical Oncology fellow at MD Anderson. Beth (Elizabeth) Barbera, MD (@elizcarpenter16) is a General Surgery physician in the United States Air Force station at RAF Lakenheath. Joe (Joseph) Broderick, MD, MA (@joebrod5) is a General Surgery research resident between his second and third year at Brooke Army Medical Center. Galen Gist, MD (@gistgalen) is a General Surgery research resident between his second and third year at Brooke Army Medical Center. Learning Objectives: 1) Review the presentation of patients with pheochromocytomas. 2) Review the work up of patients with pheochromocytomas. 3) Review the treatment of patients with pheochromocytomas. 4) Review the surveillance of patients with pheochromocytomas. References used in the making of this episode: Patel D. Surgical approach to patients with pheochromocytoma. Gland Surg. 2020;9(1):32-42. doi:10.21037/gs.2019.10.20. PMID: 32206597; PMCID:PMC7082266. Eisenhofer G, Lenders JW, Siegert G, et al. Plasma methoxytyramine: a novel biomarker of metastatic pheochromocytoma and paraganglioma in relation to established risk factors of tumour size, location and SDHB mutation status. Eur J Cancer. 2012;48(11):1739-1749. doi:10.1016/j.ejca.2011.07.016. PMID:22036874; PMCID: PMC3372624. Lenders JWM, Eisenhofer G, Mannelli M, Pacak K. Phaeochromocytoma. Lancet. 2005;366(9486):665-675. doi:10.1016/S0140-6736(05)67139-5. Vicha A, Musil Z, Pacak K. Genetics of pheochromocytoma and paraganglioma syndromes: new advances and future treatment options. Curr Opin Endocrinol Diabetes Obes. 2013;20(3):186-191. doi:10.1097/MED.0b013e32835fcc45. PMID: 23481210; PMCID: PMC4711348. https://pubmed.ncbi.nlm.nih.gov/23481210/ Dickson PV, Alex GC, Grubbs EG, et al. Posterior retroperitoneoscopic adrenalectomy is a safe and effective alternative to transabdominal laparoscopic adrenalectomy for pheochromocytoma. Surgery. 2011;150(3):452-458. doi:10.1016/j.surg.2011.07.004. https://pubmed.ncbi.nlm.nih.gov/21878230/ Lei K, Wang X, Yang Z, et al. Comparison of the retroperitoneal laparoscopic adrenalectomy versus transperitoneal laparoscopic adrenalectomy for large (≥6 cm) pheochromocytomas: a single-centre retrospective study. Front Oncol. 2023;13:1043753. doi:10.3389/fonc.2023.1043753. PMID: 36910608; PMCID: PMC9992891. https://pubmed.ncbi.nlm.nih.gov/36910608/ Please visit https://behindtheknife.org to access other high-yield surgical education podcasts, videos and more. If you liked this episode, check out our recent episodes here: https://behindtheknife.org/listen Behind the Knife Premium: General Surgery Oral Board Review Course: https://behindtheknife.org/premium/general-surgery-oral-board-review Trauma Surgery Video Atlas: https://behindtheknife.org/premium/trauma-surgery-video-atlas Dominate Surgery: A High-Yield Guide to Your Surgery Clerkship: https://behindtheknife.org/premium/dominate-surgery-a-high-yield-guide-to-your-surgery-clerkship Dominate Surgery for APPs: A High-Yield Guide to Your Surgery Rotation: https://behindtheknife.org/premium/dominate-surgery-for-apps-a-high-yield-guide-to-your-surgery-rotation Vascular Surgery Oral Board Review Course: https://behindtheknife.org/premium/vascular-surgery-oral-board-audio-review Colorectal Surgery Oral Board Review Course: https://behindtheknife.org/premium/colorectal-surgery-oral-board-audio-review Surgical Oncology Oral Board Review Course: https://behindtheknife.org/premium/surgical-oncology-oral-board-audio-review Cardiothoracic Oral Board Review Course: https://behindtheknife.org/premium/cardiothoracic-surgery-oral-board-audio-review Download our App: Apple App Store: https://apps.apple.com/us/app/behind-the-knife/id1672420049 Android/Google Play: https://play.google.com/store/apps/details?id=com.btk.app&hl=en_US
Dr. Kiran Thakur talks with Dr. Ava Easton about the World Health Organization's technical brief on encephalitis. Read the related article in The Lancet. Disclosures can be found at Neurology.org.
We've talked about eco-anxiety before on Do You Really Know, and it's real. A survey published in the Lancet in December 2021 found that 75% of young people thought the future was frightening. But others are preaching a more positive outlook, with cautious climate optimism looking set to be a trend in 2023. While our fears around the climate crisis are justified and useful, if they paralyse us out of doing anything, those feelings of hopelessness are inevitable. Psychologists call it “learned helplessness”. What cause is there for optimism? What are the arguments against climate optimism? In under 3 minutes, we answer your questions! To listen to more episodes, click here: Should I walk 10000 steps a day? What is a vertiport? What is productivity paranoia? A Bababam Originals podcast. Written and produced by Joseph Chance. First Broadcast: 20/1/2023 Learn more about your ad choices. Visit megaphone.fm/adchoices
In this lively new episode of The Food Professor Podcast, Michael LeBlanc and Dr. Sylvain Charlebois dive into the latest food, retail, and agriculture headlines before sitting down with a fascinating guest: Bryce Lobreau, Co-Founder of 8 Acres, one of Canada's most innovative organic and grass-fed beef brands.The episode begins with a timely look at Canadians' Thanksgiving dinner costs for 2025. Sylvain shares the results of his annual food price survey, which shows some rare good news: overall holiday meal costs are essentially flat compared to last year, with turkey and fresh produce slightly cheaper. However, canned items like cranberries and pumpkin pie fillings are more expensive due to tariffs on aluminum packaging. The hosts debate changing consumer choices at Thanksgiving, including a move toward lamb and premium proteins.From there, Michael and Sylvain analyze the broader North American food landscape. They unpack the impact of a potential U.S. government shutdown on Canadian agriculture, food inspections, and border trade. The duo also explore the ongoing pistachio recall tied to salmonella contamination, with Sylvain warning consumers to toss any pistachio products they may still have at home. Dairy access in trade negotiations between Canada and the U.S. also comes under scrutiny, with Sylvain highlighting the structural problems in Canada's supply management system. Other hot topics include soybean market disruptions caused by Chinese buying patterns, Canada Post strikes affecting grocery flyers, wildfire impacts on crop yields, and the surprising growth of sushi sales in North American grocery stores.The second half of the show features an in-depth conversation with Bryce Lobreau of 8 Acres. Bryce shares his journey as a third-generation Manitoba farmer who pivoted into organic cattle ranching to survive tough agricultural markets. He and his business partner, Ben Stewart, have built 8Acres into a pioneering national brand, raising over 3,000 head of cattle across certified organic and grass-fed programs. Bryce explains the challenges of scaling in today's cattle market, from soaring calf prices to attracting new ranchers to transition into organics.Listeners will also hear how 8Acres is embracing regenerative agriculture practices, integrating livestock into cropping systems, extending grazing periods, and even experimenting with live-stream farm cameras to build transparency with consumers. Bryce candidly discusses “farmer guilt” around pricing, the importance of branding in Canada's protein sector, and his vision of making organic and grass-fed beef mainstream in Canadian grocery stores over the next decade. Here is the link to buy Sylvain's great Poutine Nation:https://utpdistribution.com/9781487541781/poutine-nation/ The Food Professor #podcast is presented by Caddle. About UsDr. Sylvain Charlebois is a Professor in food distribution and policy in the Faculties of Management and Agriculture at Dalhousie University in Halifax. He is also the Senior Director of the Agri-food Analytics Lab, also located at Dalhousie University. Before joining Dalhousie, he was affiliated with the University of Guelph's Arrell Food Institute, which he co-founded. Known as “The Food Professor”, his current research interest lies in the broad area of food distribution, security and safety. Google Scholar ranks him as one of the world's most cited scholars in food supply chain management, food value chains and traceability.He has authored five books on global food systems, his most recent one published in 2017 by Wiley-Blackwell entitled “Food Safety, Risk Intelligence and Benchmarking”. He has also published over 500 peer-reviewed journal articles in several academic publications. Furthermore, his research has been featured in several newspapers and media groups, including The Lancet, The Economist, the New York Times, the Boston Globe, the Wall Street Journal, Washington Post, BBC, NBC, ABC, Fox News, Foreign Affairs, the Globe & Mail, the National Post and the Toronto Star.Dr. Charlebois sits on a few company boards, and supports many organizations as a special advisor, including some publicly traded companies. Charlebois is also a member of the Scientific Council of the Business Scientific Institute, based in Luxemburg. Dr. Charlebois is a member of the Global Food Traceability Centre's Advisory Board based in Washington DC, and a member of the National Scientific Committee of the Canadian Food Inspection Agency (CFIA) in Ottawa. Michael LeBlanc is the president and founder of M.E. LeBlanc & Company Inc, a senior retail advisor, keynote speaker and now, media entrepreneur. He has been on the front lines of retail industry change for his entire career. Michael has delivered keynotes, hosted fire-side discussions and participated worldwide in thought leadership panels, most recently on the main stage in Toronto at Retail Council of Canada's Retail Marketing conference with leaders from Walmart & Google. He brings 25+ years of brand/retail/marketing & eCommerce leadership experience with Levi's, Black & Decker, Hudson's Bay, CanWest Media, Pandora Jewellery, The Shopping Channel and Retail Council of Canada to his advisory, speaking and media practice.Michael produces and hosts a network of leading retail trade podcasts, including the award-winning No.1 independent retail industry podcast in America, Remarkable Retail with his partner, Dallas-based best-selling author Steve Dennis; Canada's top retail industry podcast The Voice of Retail and Canada's top food industry and one of the top Canadian-produced management independent podcasts in the country, The Food Professor with Dr. Sylvain Charlebois from Dalhousie University in Halifax.Rethink Retail has recognized Michael as one of the top global retail experts for the fourth year in a row, Thinkers 360 has named him on of the Top 50 global thought leaders in retail, RTIH has named him a top 100 global though leader in retail technology and Coresight Research has named Michael a Retail AI Influencer. If you are a BBQ fan, you can tune into Michael's cooking show, Last Request BBQ, on YouTube, Instagram, X and yes, TikTok.Michael is available for keynote presentations helping retailers, brands and retail industry insiders explaining the current state and future of the retail industry in North America and around the world.
Pulse has a brand-new format — Hot Topics only! Louise and George dive straight into the biggest stories shaping digital health right now.The cost of lies: From the US President's paracetamol claim to Tina Purnat's new Lancet paper, we explore why misinformation isn't just a trust issue but a global operational and financial burden.Wearables grow up: A fresh NEJM survey shows wearables are moving from gimmicks to clinical tools — but will insurers, EHRs, and workflows catch up?Aussie pride: Nine Australian companies make Time's 2025 Top HealthTech list. From AI to aged care, we unpack how local innovators are scaling globally.Why doctors hate their EPRs: A new UK survey confirms what many clinicians already know — clunky systems slow care. But implementation may matter more than the software itself.One scan, two diagnoses: Australian researchers unveil an AI that predicts cardiovascular risk from mammograms — doubling the impact of routine screening.Resources:Gerontology conference in Hong Kong LinkNavigating information space: the role of health-care providers — The Lancet Primary Care LinkThe information environment as a determinant of health LinkWearable Health Technologies Are on the Rise — NEJM CatalystTime's World's Top HealthTech Companies of 2025 LinkUK EPR Usability Survey Report LinkAustralian-developed AI algorithm predicts cardiovascular risk using mammograms —Pulse+ITADHA Digital Health Adviser roles. Applications close 16 October LinkVisit Pulse+IT.news to subscribe to breaking digital news, weekly newsletters and a rich treasure trove of archival material. People in the know, get their news from Pulse+IT – Your leading voice in digital health news.Follow us on LinkedIn Louise | George | Pulse+ITFollow us on BlueSky Louise | George | Pulse+ITSend us your questions pulsepod@pulseit.newsProduction by Octopod Productions | Ivan Juric
Donate (no account necessary) | Subscribe (account required) Join Bryan Dean Wright, former CIA Operations Officer, as he dives into today's top stories shaping America and the world. In this episode of The Wright Report, we cover the federal government shutdown, Pete Hegseth's blunt message to America's generals, new immigration updates from Chicago to Central America, and surprising global research on obesity. From furloughs in Washington to fat generals at the Pentagon, today's brief connects politics, security, and science shaping America's future. Federal Government Shutdown Begins: Negotiations collapsed after Democrats demanded $1 trillion for health care tied to Biden's immigration surge. Trump warned, “We can do things during the shutdown that are irreversible,” and began cutting federal workers, including 100 FBI agents. Essential services like Social Security remain open, while departments like Labor shutter. Bryan notes, “This shutdown is ultimately about an argument I thought we settled last November.” Pete Hegseth Calls Out Fat Generals: The Secretary of War unveiled a 10-point plan to toughen the military, starting with weight and fitness standards for all ranks. “It is tiring to look out… at any formation and see fat troops,” Hegseth said. The plan includes tougher boot camp, one combat standard for men and women, and no more promotions based on quotas. Trump joked, “Pete gave a great speech… but I don't want him to get so good I can't go on after that.” Immigration Updates from Chicago to Central America: Four leftist protesters attacked an ICE facility in Chicago, one threatening, “I'll f------ kill you right now.” In Portland, illegals shined lasers at a CBP helicopter. In Iowa, ICE arrested a school superintendent who was in the country illegally and registered to vote. Meanwhile, Bloomberg reports migrants are sending record remittances home — $161 billion projected this year — fearing deportation. Bryan says, “Migrants are getting while the getting is good.” Obesity Campaigns Fail Worldwide: A new Lancet study found that none of 17 childhood obesity programs worked, even with parental training and nutrition education. French researchers concluded rising caloric intake is the real driver, echoing why drugs like Ozempic work by cutting appetite. Bryan quips, “I put a new picture of Pete Hegseth on my fridge. I've already lost five pounds.” "And you shall know the truth, and the truth shall make you free." - John 8:32 Keywords: federal government shutdown 2025, Trump irreversible budget cuts quote, FBI agents fired shutdown, Pete Hegseth fat generals 10 point plan, military fitness standards women combat, Chicago ICE attack leftist protesters, Portland illegals laser CBP helicopter, Iowa illegal superintendent voter registration, migrant remittances $161 billion Bloomberg, Lancet obesity study children, French study caloric intake obesity, Ozempic Wegovy appetite suppression
In this episode of the Let's Talk Brain Health Podcast, we welcome Dr. Kellyann Niotis, MD, the world's first fellowship-trained preventive neurologist, who shares her insights on early detection and risk reduction for neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease, and Lewy body dementia. Dr. Niotis discusses the emerging field of preventive neurology, the role of blood biomarkers and genetic testing, and the importance of lifestyle choices in maintaining brain health. She also highlights the impact of cholesterol management, sleep studies, and the significance of personalized care approaches. Join us as we dive into a comprehensive discussion about the future of brain health and the proactive steps we can take today for healthier brains tomorrow.00:00 Introduction to Dr. Kellyann Niotis, MD02:47 What is Preventive Neurology?06:08 The Role of Biomarkers in Early Detection13:52 Lifestyle Modifications and Brain Health17:12 Cholesterol and Brain Health24:15 The Impact of Statins on Cognition26:05 Underutilized Tools in Brain Health30:11 Rapid Fire Questions and Final ThoughtsResourcesConnect with Kellyann on Instagram @drkellyannniotis Visit her website and learn more about her new clinic on their websiteResearchLearn more about the research-informed brain health risks mentioned in this episode from the “Dementia prevention, intervention, and care: 2024 report of the Lancet standing Commission” ReportRead more about Dr. Lisa Misconi's research on how estrogen receptors are unregulated in perimenopause in this research article
Welcome to Ozempic Weightloss Unlocked, where we dive into the latest breakthroughs and controversies surrounding Ozempic, its medical use, and its impact on everyday wellness.The big headline this month is the arrival of a new pill form of semaglutide, the main ingredient in Ozempic. According to The New England Journal of Medicine, people who took this daily pill lost almost 14 percent of their body weight over 64 weeks, compared to just 2 percent for those on a placebo. Fifty percent of the patients shed at least 15 percent of their weight, with nearly a third losing 20 percent or more. Novo Nordisk, the company that makes Ozempic, announced even stronger results for those who stuck to their treatment plan, with close to 17 percent average weight loss. This pill, pending approval, could be a game changer for people who prefer not to take injections.On the injectable front, clinical trials featured in The Lancet indicate that a higher 7.2 milligram weekly dose of semaglutide in adults without diabetes led to almost 19 percent average weight loss, higher than what's seen with lower doses. These numbers highlight ongoing efforts to increase the effectiveness of Ozempic for those struggling with obesity.Yet, it's crucial to balance these promising results with real-world insights. The Mayo Clinic and NYU Langone Health recently compared Ozempic's results to traditional weight loss surgery, like gastric bypass and sleeve gastrectomy. Their research revealed that surgery is five times more effective than GLP-1 drugs such as Ozempic, with surgical patients losing an average of 58 pounds after two years versus just 12 pounds for those on the drug for six months. Experts also noted that only 30 percent of patients stick with GLP-1 drugs for longer than a year, and real-world weight loss may be lower than trial results suggest. Surgery, however, isn't without its risks, including potential infections, blood clots, and hernias, and requires strict diet and lifestyle changes afterward.Turning to genetics, Cleveland Clinic research shows that the effectiveness of Ozempic may depend on your DNA. A specific variant in the Neurobeachin gene seems to make some people much more responsive to these medications, leading to 82 percent higher odds of substantial weight loss. This new insight could help doctors tailor treatments so patients get therapies most suited to their genetic profile.Lifestyle stakes are high, and so are concerns about side effects and safety. Recent studies report that Ozempic may cause severe conditions such as gastroparesis, bowel blockages, pancreatic and kidney injuries, and vision problems. Even hair loss is emerging as a potentially significant side effect, especially for women—according to recent findings, female users experienced about twice the rate of hair loss compared to those not using Ozempic.Because of these risks, there are currently over two thousand active lawsuits against Novo Nordisk and other GLP-1 manufacturers, with ongoing multidistrict litigation. These lawsuits allege that the companies did not give enough warning about the dangers, and some patients claim life-changing or life-threatening complications.Compounded GLP-1 drugs, made in pharmacies rather than by pharmaceutical companies, became popular when Ozempic was in short supply. However, the FDA warns that compounded drugs can be risky because they're not evaluated for safety or effectiveness. While the shortage has officially ended, compounded formulations remain in circulation.If you are considering Ozempic—whether as a pill, injection, or a compounded version—talk with your healthcare provider and review your health history, genetic background, and lifestyle goals. Widespread interest has led to changing availability, promising new forms, and more transparent labeling, especially after recent updates about kidney and pancreatic risks.To sum up, Ozempic continues to make waves as both a treatment for diabetes and a potent tool for weight loss. With fresh news about new pill forms, higher effective doses, genetic influences, and ongoing legal cases, it's important to stay informed and make choices based on both science and your personal health needs.Thanks for tuning in to Ozempic Weightloss Unlocked. Don't forget to subscribe to stay up to date on the latest developments. This has been a Quiet Please production, for more check out quiet please dot ai. Some great Deals https://amzn.to/49SJ3QsFor more check out http://www.quietplease.aiThis content was created in partnership and with the help of Artificial Intelligence AI
Professors Guy Brusselle and Celeste Porsbjerg join us to discuss their recent Series papers on asthma, which will be featured in a cross journal project with The Lancet, published to coincide with a Lancet journal session on asthma at ERS in Amsterdam. The Series aims to provide an overview of recent research advances related to asthma; to provide new insights into the genetics, prevention and risk factors for asthma; review advances arising as a result of the use of monoclonal antibody therapeutics; and assess remission in adult patients. Late breaking research will also be included within the journal session and linked to the Series.Continue this conversation on social!Follow us today at...https://thelancet.bsky.social/https://instagram.com/thelancetgrouphttps://facebook.com/thelancetmedicaljournalhttps://linkedIn.com/company/the-lancethttps://youtube.com/thelancettv
Across healthcare, new technologies often land in the hands of nurses without their input, adding complexity instead of easing it. In the age of artificial intelligence, more than ever, leaving nurses out of the design process risks creating tools that miss the mark, fail to build trust, threaten safety and security, and can add to the very burdens they're meant to relieve. In this episode of our AI in Play series, we meet Ryannon Frederick, MS, RN, System Chief Nursing Officer at Mayo Clinic, who has restructured nursing leadership teams to ensure nurses identify the problems, co-develop the solutions, and remain partners from design through implementation and testing. Frederick shares how this “for nurses, by nurses” model is transforming innovation at Mayo, making nursing work visible, rebuilding trust in technology, and delivering tools like ambient documentation and nurse virtual assistants that give time back to patients and strengthen the workforce. Find this episode's resources at www.seeyounowpodcast.com, and for more information on the podcast bundles, visit ANA's Innovation Website at: https://www.nursingworld.org/practice-policy/innovation/education/. Have questions for the SEE YOU NOW team? Feedback? Future episode ideas? Contact us at: hello@seeyounowpodcast.com. Resources Enabling nurses' engagement in the design of healthcare technology – Core competencies and requirements: A qualitative study (2024) BMC Nursing. https://www.sciencedirect.com/science/article/pii/S2666142X23000541?via%3Dihub Impact of Bottom-Up Cocreation of Nursing Technological Innovations: Explorative Interview Study Among Hospital Nurses and Managers (2025).JMIR. https://humanfactors.jmir.org/2025/1/e60543/ Global prevalence and contributing factors of nurse burnout: an umbrella review of systematic review and meta-analysis. (2025) BMC Nursing. https://bmcnurs.biomedcentral.com/articles/10.1186/s12912-025-03266-8 Documentation Burden in Nursing and Its Role in Clinician Burnout Syndrome. (2022) ACI. https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0042-1757157 Addressing burnout in the healthcare workforce: current realities and mitigation strategies. (2024) The Lancet. https://www.thelancet.com/journals/lanepe/article/PIIS2666-7762(24)00128-5/fulltext
Dr. Deanna Saylor talks with Dr. Senjuti Saha about colonialism in global health and the importance of pathogen genomics. Read the related article in The Lancet. Disclosures can be found at Neurology.org.
In this journal club, we will discuss two pivotal studies in ILD, the FIBRONEER study and the RECITAL study: Nerandomilast in Patients with Progressive Pulmonary Fibrosis, Maher, T.M. et al. NEJM. 2025 May 19. doi: 10.1056 Rituximab versus intravenous cyclophosphamide in patients with connective tissue disease-associated interstitial lung disease in the UK (RECITAL): a double-blind, double-dummy, randomised, controlled, phase 2b trial, Maher T.M., et al. Lancet 2023 Jan;11(1). doi: 10.1016 Panelists: Toby Maher, MD Shervin Assassi, MD Jack Cush, Moderator
L'arrivée de la nouvelle administration Trump début 2025 a sonné la fin de l'USAID, l'agence du gouvernement des États-Unis chargée du développement économique et de l'aide humanitaire dans le monde. Selon une étude publiée par The Lancet le 1ᵉʳ juillet, l'effondrement des financements américains qui étaient dédiés à l'aide internationale pourrait entraîner la mort de plus de 14 millions de personnes. Quelles répercussions concrètes cela a sur le terrain pour les acteurs de santé ? Nous posons la question à des activistes de santé en Afrique. Dr Bintou Kéita Dembele, médecin directrice d'ARCAD/SIDA au Mali (ARCAD-SIDA est la première association de lutte contre le Sida au Mali) Denise Ngatchou, directrice exécutive de Horizons Femmes au Cameroun Dr Ephrem Mensah, médecin généraliste, directeur exécutif de l'ONG Espoir Vie-Togo (EVT) dont le siège est à Lomé. Programmation musicale : ► Boy Spyce, Jeriq – Achalugo ► Sahad – Vultures.
L'arrivée de la nouvelle administration Trump début 2025 a sonné la fin de l'USAID, l'agence du gouvernement des États-Unis chargée du développement économique et de l'aide humanitaire dans le monde. Selon une étude publiée par The Lancet le 1ᵉʳ juillet, l'effondrement des financements américains qui étaient dédiés à l'aide internationale pourrait entraîner la mort de plus de 14 millions de personnes. Quelles répercussions concrètes cela a sur le terrain pour les acteurs de santé ? Nous posons la question à des activistes de santé en Afrique. Dr Bintou Kéita Dembele, médecin directrice d'ARCAD/SIDA au Mali (ARCAD-SIDA est la première association de lutte contre le Sida au Mali) Denise Ngatchou, directrice exécutive de Horizons Femmes au Cameroun Dr Ephrem Mensah, médecin généraliste, directeur exécutif de l'ONG Espoir Vie-Togo (EVT) dont le siège est à Lomé. Programmation musicale : ► Boy Spyce, Jeriq – Achalugo ► Sahad – Vultures.
Maternal perception of decreased fetal movement at term occurs in up to 15% of pregnancies and is a cause for maternal and provider concern. All maternal concerns of decreased fetal movement require an assessment of fetal wellbeing. But what about the patient with recurrent episodes of reduced fetal movements at term? Routine induction of labor is not supported solely for decreased fetal movement in a non-growth-restricted fetus, as increased intervention rates (including induction of labor and early term birth) have not demonstrated improved perinatal outcomes and may increase neonatal morbidity, such as respiratory distress and NICU admission. Some international sources (ISUOG) have recognized the cerebroplacental ratio (CPR) as a possible ultrasound tool to investigate possible early placental insufficiency before fetal growth restriction occurs. Is CPR helpful for decreased fetal movements at term? A new publication from the Lancet's new journal- Obstetrcis, Gynecology, and Women's Health- states that it is. Is the CPR ultrasound assessment recognized by the ACOG or SMFM? Listen in for details. 1. The cerebroplacental ratio: a useful marker but should it be a screening test? (2025): https://obgyn.onlinelibrary.wiley.com/doi/10.1002/uog.29154#:~:text=The%20ISUOG%20guidelines%20recommend%20using,after%2038%20weeks'%20gestation44.2. Turner JM, Flenady V, Ellwood D, Coory M, Kumar S.Evaluation of Pregnancy Outcomes Among Women With Decreased Fetal Movements.JAMA logoJAMA Network Open. 2021;4(4):e215071. doi:10.1001/jamanetworkopen.2021.5071.3. Cerebroplacental ratio-based management versus care as usual in non-small-for-gestational-age fetuses at term with maternal perceived reduced fetal movements (CEPRA): a multicentre, cluster-randomised controlled trial. https://www.sciencedirect.com/science/article/pii/S30505038250000204. Hofmeyr GJ, Novikova N. Management of Reported Decreased Fetal Movements for Improving Pregnancy Outcomes. The Cochrane Database of Systematic Reviews. 2012;(4):CD009148. doi:10.1002/14651858.CD009148.pub2.STRONG COFFEE PROMO: 20% Off Strong Coffee Company https://strongcoffeecompany.com/discount/CHAPANOSPINOBG
00:02:10 – Jimmy Kimmel Pulled Off AirKimmel is suspended after mocking Trump, with the FCC accused of pressuring networks into compliance. 00:07:43 – Bureaucracy as Speech PoliceUnelected regulators weaponize licenses and rules to censor content, compared to mafia-style intimidation. 00:24:52 – Both Parties Embrace CensorshipAnalysis that Republicans and Democrats alike are now justifying cancel culture, betraying Kirk's free speech legacy. 00:49:57 – Israel Lobby & Boycott BansConcerns about pro-Israel groups pushing GOP leaders to outlaw boycotts, further undermining free speech. 00:55:09 – Bondi vs. Kirk on Hate SpeechPam Bondi calls to outlaw hate speech, directly contradicting Kirk's past defense of free expression. 01:15:23 – Golden Trump Statue & Cult ImageryDiscussion of Trump's cult-like following, including a golden statue erected in DC, and how his lawsuits read like propaganda hagiographies. 01:18:08 – Weaponizing Lawsuits & CensorshipConcerns that Trump's lawfare isn't about winning in court but punishing media through process, intimidation, and regulatory pressure. 01:47:00 – Dearborn Mayor Tells Christian to LeaveMayor of Dearborn, Michigan tells a resident critical of Hezbollah/Hamas sympathizers that he is “not welcome” in the city, highlighting cultural tensions. 01:50:24 – Gaza, Netanyahu & Just WarDebate over Israel's war in Gaza, Trump's anger at Netanyahu for targeting Hamas leaders in Doha, and the moral principles of just war. 02:06:26 – Celente on Hate Speech & Endless WarsGerald Celente blasts the hypocrisy of labeling dissent as “hate speech” while U.S. presidents wage murderous wars, citing Obama, Clinton, and Bush. 02:10:15 – Trump's Broken Peace PromisesTrump is accused of lying about ending wars while escalating Venezuela strikes. Comparisons are drawn to Duterte's extrajudicial killings in the Philippines. 02:15:53 – Israel, Genocide & Kushner's DealsDiscussion of U.S. support for Israeli bombardment of Gaza, Kushner's billion-dollar Gulf investments, and how financial interests override peace. 02:33:56 – Venezuela, Oil & U.S. MeddlingAnalysis of U.S. attempts to overthrow Maduro, framed as another “war for oil” racket. Corporate and political elites are accused of profiting from intervention. 02:36:21 – We the People's Party VisionCelente announces domain registrations for “We the People's Party,” arguing populism is the future and rallies like “Unite the Kingdom” show the growing pushback. 02:47:21 – FCC Shakedowns & Open CorruptionTrump's use of FCC pressure to extract millions from CBS and Paramount is described as mafia-style extortion. 03:54:37 – Gaza Death Toll & Zionism CritiqueConversation returns to Gaza with Lancet estimates of 200,000 deaths, while U.S. leaders openly align with Israeli policy. Zionism is critiqued as a political ideology, not faith. 02:57:29 – Peace Rally & Isolationist LabelCelente promotes his upcoming Occupy Peace rally, arguing that rejecting endless wars isn't isolationism but moral necessity. Follow the show on Kick and watch live every weekday 9:00am EST – 12:00pm EST https://kick.com/davidknightshow Money should have intrinsic value AND transactional privacy: Go to https://davidknight.gold/ for great deals on physical gold/silverFor 10% off Gerald Celente's prescient Trends Journal, go to https://trendsjournal.com/ and enter the code KNIGHTFind out more about the show and where you can watch it at TheDavidKnightShow.com If you would like to support the show and our family please consider subscribing monthly here: SubscribeStar https://www.subscribestar.com/the-david-knight-showOr you can send a donation throughMail: David Knight POB 994 Kodak, TN 37764Zelle: @DavidKnightShow@protonmail.comCash App at: $davidknightshowBTC to: bc1qkuec29hkuye4xse9unh7nptvu3y9qmv24vanh7Become a supporter of this podcast: https://www.spreaker.com/podcast/the-david-knight-show--2653468/support.
CraftLit - Serialized Classic Literature for Busy Book Lovers
Ep. 696: Mr. Harrison's Confessions | Chapters 3-4 Book talk begins at 25:15 Pears, parties, and peculiar housemates—Mr. Harrison's adventures just keep getting more awkward (and more entertaining). --------------------------------------------------------------- SEPTEMBER Raffle - THIS WEEK'S TEA: and (thank you LilyM) We caught Hank The Ultimate video from @KristineVike And the evil of (actually, she has a LOT of useful informational videos!) Spectacular FIXED SciShow video: I Remade the SciShow Knitting Video (with accurate SCIENCE) Solomon's Seal: Dutch Tiles—as with Cranford, these were out of style when the story was written/takes place. They have a resurgence of popularity during the Arts & Crafts movement: The Jargonelle pear () is an ancient, hardy, long-lived pear variety, first mentioned in the 17th century. It produces medium-sized, yellow-green fruit with a reddish flush and musky, sweet, juicy flesh, ripe in late summer. The fruit must be eaten fresh as it does not store well. & again Duncombe (silent final “be”) The back room was my consulting-room (“the library,” he advised me to call it), and he gave me a skull to put on the top of my bookcase, in which the medical books were all ranged on the conspicuous shelves; while Miss Austen, Dickens and Thackeray were, by Mr. Morgan himself, skilfully placed in a careless way, upside down or with their backs turned to the wall. HA! Women's veils: deep widow's mourning; such veils and fails, and capes and cloaks, that she looked like a black crape haycock. very mal-àpropos that I could hardly keep from smiling; but I would not have done it for the world, … ‘“I have the ‘dognoses' of my dear husband's complaint in my desk, Mr. Harrison, if you would like to draw up the case for the Lancet. : is a comedic character from Richard Brinsley Sheridan's 1775 play The Rivals. She is a pretentious and self-important aunt who constantly makes humorous verbal blunders by using words that sound similar to, but are inappropriate for, the intended word. This type of linguistic error is now known as a . Her name is derived from the French term “mal à propos,” which means “inappropriate” or “poorly placed”. ***a memorable scene occurs when she instructs her niece, Lydia Languish, on the importance of controlling her passions, famously advising her to begin matrimony with “a little aversion,” and later attempts to describe Lydia's headstrong nature by calling her “as headstrong as an allegory on the banks of the Nile”. then She tells Lydia that she must forget the young man, saying, “But I say it is, miss; there is nothing on earth so easy as to forget, if a person chooses to set about it. I'm sure I have as much forgot your poor dear uncle as if he had never existed”. Miscellaneous BOOK/WATCH PARTIES coming up in 2025: Last Thursday of every month, 8pm Eastern: Sep—The Last Unicorn (movie) Oct—Random Harvest (book) Nov—Random Harvest (movie) Dec—Lamb: The Gospel According to Biff, Christ's Childhood Pal (book) *CraftLit's Socials* • Find everything here: https://www.linktr.ee/craftlitchannel • Join the newsletter: http://eepurl.com/2raf9 • Podcast site: http://craftlit.com • Facebook: https://www.facebook.com/CraftLit/ • Facebook group: https://www.facebook.com/groups/craftlit • Pinterest: https://www.pinterest.com/craftlit/ • TikTok podcast: https://www.tiktok.com/@craftlit • Email: heather@craftlit.com • Previous CraftLit Classics can be found here: https://bit.ly/craftlit-library-2023 *SUPPORT THE SHOW!* • CraftLit App Premium feed bit.ly/libsynpremiumcraftlit (only one tier available) • PATREON: https://patreon.com/craftlit (all tiers, below) ——Walter Harright - $5/mo for the same audio as on App ——Jane Eyre - $10/mo for even-month Book Parties ——Mina Harker - $15/mo for odd-month Watch Parties *All tiers and benefits are also available as* —*YouTube Channel Memberships* —*Ko-Fi* https://ko-fi.com/craftlit —*NEW* at CraftLit.com — Premium Memberships https://craftlit.com/membership-levels/ *IF you want to join a particular Book or Watch Patry but you don't want to join any of the above membership options*, please use PayPal.me/craftlit or CraftLit @ Venmo and include what you want to attend in the message field. Please give us at least 24 hours to get your message and add you to the attendee list. • Download the FREE CraftLit App for iOS or Android (you can call or email feedback straight from within the app) • Call 1-206-350-1642
00:02:10 – Jimmy Kimmel Pulled Off AirKimmel is suspended after mocking Trump, with the FCC accused of pressuring networks into compliance. 00:07:43 – Bureaucracy as Speech PoliceUnelected regulators weaponize licenses and rules to censor content, compared to mafia-style intimidation. 00:24:52 – Both Parties Embrace CensorshipAnalysis that Republicans and Democrats alike are now justifying cancel culture, betraying Kirk's free speech legacy. 00:49:57 – Israel Lobby & Boycott BansConcerns about pro-Israel groups pushing GOP leaders to outlaw boycotts, further undermining free speech. 00:55:09 – Bondi vs. Kirk on Hate SpeechPam Bondi calls to outlaw hate speech, directly contradicting Kirk's past defense of free expression. 01:15:23 – Golden Trump Statue & Cult ImageryDiscussion of Trump's cult-like following, including a golden statue erected in DC, and how his lawsuits read like propaganda hagiographies. 01:18:08 – Weaponizing Lawsuits & CensorshipConcerns that Trump's lawfare isn't about winning in court but punishing media through process, intimidation, and regulatory pressure. 01:47:00 – Dearborn Mayor Tells Christian to LeaveMayor of Dearborn, Michigan tells a resident critical of Hezbollah/Hamas sympathizers that he is “not welcome” in the city, highlighting cultural tensions. 01:50:24 – Gaza, Netanyahu & Just WarDebate over Israel's war in Gaza, Trump's anger at Netanyahu for targeting Hamas leaders in Doha, and the moral principles of just war. 02:06:26 – Celente on Hate Speech & Endless WarsGerald Celente blasts the hypocrisy of labeling dissent as “hate speech” while U.S. presidents wage murderous wars, citing Obama, Clinton, and Bush. 02:10:15 – Trump's Broken Peace PromisesTrump is accused of lying about ending wars while escalating Venezuela strikes. Comparisons are drawn to Duterte's extrajudicial killings in the Philippines. 02:15:53 – Israel, Genocide & Kushner's DealsDiscussion of U.S. support for Israeli bombardment of Gaza, Kushner's billion-dollar Gulf investments, and how financial interests override peace. 02:33:56 – Venezuela, Oil & U.S. MeddlingAnalysis of U.S. attempts to overthrow Maduro, framed as another “war for oil” racket. Corporate and political elites are accused of profiting from intervention. 02:36:21 – We the People's Party VisionCelente announces domain registrations for “We the People's Party,” arguing populism is the future and rallies like “Unite the Kingdom” show the growing pushback. 02:47:21 – FCC Shakedowns & Open CorruptionTrump's use of FCC pressure to extract millions from CBS and Paramount is described as mafia-style extortion. 03:54:37 – Gaza Death Toll & Zionism CritiqueConversation returns to Gaza with Lancet estimates of 200,000 deaths, while U.S. leaders openly align with Israeli policy. Zionism is critiqued as a political ideology, not faith. 02:57:29 – Peace Rally & Isolationist LabelCelente promotes his upcoming Occupy Peace rally, arguing that rejecting endless wars isn't isolationism but moral necessity. Follow the show on Kick and watch live every weekday 9:00am EST – 12:00pm EST https://kick.com/davidknightshow Money should have intrinsic value AND transactional privacy: Go to https://davidknight.gold/ for great deals on physical gold/silverFor 10% off Gerald Celente's prescient Trends Journal, go to https://trendsjournal.com/ and enter the code KNIGHTFind out more about the show and where you can watch it at TheDavidKnightShow.com If you would like to support the show and our family please consider subscribing monthly here: SubscribeStar https://www.subscribestar.com/the-david-knight-showOr you can send a donation throughMail: David Knight POB 994 Kodak, TN 37764Zelle: @DavidKnightShow@protonmail.comCash App at: $davidknightshowBTC to: bc1qkuec29hkuye4xse9unh7nptvu3y9qmv24vanh7Become a supporter of this podcast: https://www.spreaker.com/podcast/the-real-david-knight-show--5282736/support.
Stress isn't just something to “manage” — it's a signal, a teacher, and often, an invitation to look deeper at our health, our choices, and our lives. In this solo episode, Darin reframes stress not as an enemy, but as a dashboard light pointing toward misalignments in our nervous system, environment, relationships, and purpose. Drawing on science, practical tools, and personal insight, Darin reveals how layered stress silently drains our vitality — and how to transform it into an ally for growth, healing, and deeper contentment. Whether it's hidden trauma, toxic environments, unresolved conflict, or the modern distractions constantly pulling at our attention, Darin lays out a roadmap to stop the leaks and reclaim the energy already within you. This episode is a powerful reminder: stress isn't the end of the story — it's the beginning of awareness, safety, and a super life. What You'll Learn in This Episode [00:00] Introduction to the Super Life podcast [03:27] Why stress might not be your enemy [04:17] Stress as an ally: the signals it gives us about misalignment [04:32] The dashboard light metaphor: how stress reveals hidden issues [05:28] The illusion of “no choice” and the infinite possibilities always available [06:12] Global stress statistics and why most people underestimate their stress load [07:23] Hidden stress revealed through heart rate variability and physiology [08:23] Layered stress: how sleep, exercise, and poor choices compound each other [09:25] Safety vs. calm — why your nervous system craves safety first [10:15] Trauma and the unconscious mind: how old wounds drive our stress response [11:54] Inner narratives and negative self-talk as hidden stress multipliers [12:22] The role of community and your social field in stress and resilience [13:53] Relationships, honesty, and how your circle shapes your energy [14:55] Why boundaries around media and politics are vital for mental clarity [17:42] Finding micro-purpose when life feels overwhelming [18:52] Environmental layers of stress — light, air, and clutter [19:15] The existential layer: stress from living without service or purpose [20:12] Stress as a risk amplifier — how it undermines healing and health [20:55] The deeper truth of safety, connection, and higher power [23:00] Practical tools: breathing, grounding, nature, and conscious choices [24:01] Trauma reframed: not a problem, but a protector at the time [25:25] Lessons from Peter Levine and wild animals: releasing trauma physically [26:04] Questions to ask trauma: “What are you protecting me from?” [26:56] Stress as a multiplier of aging, disease, and poor outcomes [29:20] Why stress isn't a single cause — it's layered and chronic [30:18] Anti-stress strategies: circadian rhythm, nature, and gratitude [31:49] Energy leaks to avoid: clutter, poor food, scrolling, bad boundaries [32:22] What matters most: service, contribution, and alignment [33:28] Final toolkit: breathwork, movement, nature, sleep, and gratitude [34:38] The deeper invitation: step into sovereignty and live your SuperLife Thank You to Our Sponsors: Manna Vitality: Go to mannavitality.com/ or use code DARIN20 for 20% off your order. Bite Toothpaste: Go to trybite.com/DARIN20 or use code DARIN20 for 20% off your first order. Find More from Darin Olien: Instagram: @darinolien Podcast: SuperLife Podcast Website: superlife.com Book: Fatal Conveniences Check out my podcast with Dr. Amy Abbington Key Takeaway “Stress is not the enemy. It's a dashboard light — a teacher showing you where you're out of alignment. When you reframe stress, you reclaim your energy and create space for healing, safety, and the joy of living a super life.” Bibliography (selected, peer-reviewed) Sources: Gallup Global Emotions (2024); Gallup U.S. polling (2024); APA Stress in America (2023); Natarajan et al., Lancet Digital Health (2020); Orini et al., UK Biobank (2023); Martinez et al. (2022); Leiden University (2025). Cohen S, Tyrrell DA, Smith AP. Psychological stress and susceptibility to the common cold. N Engl J Med.1991;325(9):606–612. New England Journal of Medicine Cohen S, et al. Chronic stress, glucocorticoid receptor resistance, inflammation, and disease risk. Proc Natl Acad Sci USA. 2012;109(16):5995–5999. PNAS Kiecolt-Glaser JK, et al. Slowing of wound healing by psychological stress. Lancet. 1995;346(8984):1194–1196. The Lancet Kiecolt-Glaser JK, et al. Hostile marital interactions, proinflammatory cytokine production, and wound healing.Arch Gen Psychiatry. 2005;62(12):1377–1384. JAMA Network Tawakol A, et al. Relation between resting amygdalar activity and cardiovascular events. Lancet.2017;389(10071):834–845. The Lancet Epel ES, et al. Accelerated telomere shortening in response to life stress. Proc Natl Acad Sci USA.2004;101(49):17312–17315. PNAS McEwen BS, Stellar E. Stress and the individual: mechanisms leading to disease. Arch Intern Med.1993;153(18):2093–2101. PubMed McEwen BS, Wingfield JC. Allostasis and allostatic load. Ann N Y Acad Sci. 1998;840:33–44. PubMed Felitti VJ, et al. Relationship of childhood abuse and household dysfunction to many leading causes of death in adults (ACE Study). Am J Prev Med. 1998;14(4):245–258. AJP Mon Online Edmondson D, et al. PTSD and cardiovascular disease. Ann Behav Med. 2017;51(3):316–327. PMC Afari N, et al. Psychological trauma and functional somatic syndromes: a systematic review and meta-analysis.Psychosom Med. 2014;76(1):2–11. PMC Goyal M, et al. Meditation programs for psychological stress and well-being: a systematic review and meta-analysis. JAMA Intern Med. 2014;174(3):357–368. PMC Qiu Q, et al. Forest therapy: effects on blood pressure and salivary cortisol—a meta-analysis. Int J Environ Res Public Health. 2022;20(1):458. PMC Laukkanen T, et al. Sauna bathing and reduced fatal CVD and all-cause mortality. JAMA Intern Med.2015;175(4):542–548. JAMA Network Zureigat H, et al. Physical activity lowers CVD risk by reducing stress-related neural activity. J Am Coll Cardiol.2024;83(16):1532–1546. PMC Holt-Lunstad J, Smith TB, Layton JB. Social relationships and mortality risk: a meta-analytic review. PLoS Med.2010;7(7):e1000316. PMC Chen Y-R, Hung K-W. EMDR for PTSD: meta-analysis of RCTs. PLoS One. 2014;9(8):e103676. PLOS Hoppen TH, et al. Network/pairwise meta-analysis of PTSD psychotherapies—TF-CBT highest efficacy overall.Psychol Med. 2023;53(14):6360–6374. PubMed van der Kolk BA, et al. Yoga as an adjunctive treatment for PTSD: RCT. J Clin Psychiatry. 2014;75(6):e559–e565. PubMed Kelly U, et al. Trauma-center trauma-sensitive yoga vs CPT in women veterans: RCT. JAMA Netw Open.2023;6(11):e2342214. JAMA Network Bentley TGK, et al. Breathing practices for stress and anxiety reduction: components that matter. Behav Sci (Basel). 2023;13(9):756.
A large meta-analysis in The Lancet found clopidogrel superior to aspirin for long-term secondary prevention in coronary artery disease, reducing major cardiovascular events by 14% without added bleeding risk. The REBOOT trial in NEJM showed no benefit of beta-blockers in post-MI patients with preserved ejection fraction, and even potential harm in women on high doses, prompting reevaluation of routine use. Finally, a phase 2 trial in JAMA Internal Medicine showed daily azelastine nasal spray reduced COVID-19 incidence by 67% and shortened illness duration, though larger studies are needed to confirm its prophylactic role.
Think you can out-eat or out-exercise poor sleep? You can't. Sleep isn't just rest—it's repair, it's hormone balance, it's fat burning, and it's brain detox. So if you've been working hard on your health but still feeling stuck, your sleep might be the reason your results aren't showing up. In this episode, I break down what sleep really does for your body—from hormone production and muscle repair to fat metabolism and cognitive function. I explain why just one night of poor sleep can throw your insulin, mood, and metabolism off—and what chronic sleep debt is quietly doing to your body over time. We're done treating sleep like a luxury. It's a biological necessity. What you'll learn: What your "night shift workers" are doing while you sleep (and why they're striking) Why deep and REM sleep are non-negotiable for fat loss and brain function How lack of sleep increases cravings, brain fog, and belly fat What poor sleep does to your hormones—including cortisol and testosterone 5 science-backed habits you can start tonight for better sleep Sleep is the foundation of every health goal you have—so let's stop ignoring it. Ashley's Favorite Sleep Mask Get Weekly Health Tips: thrivehealthcoachllc.com Let's Connect:@ashleythrivehealthcoach or via email: ashley@thrivehealthcoachingllc.com Podcast Produced by Virtually You! Sources: Andrews, R. C., Cooper, A. J., Montgomery, A. A., Norcross, A. J., Peters, T. J., Sharp, D. J., ... & Dayan, C. M. (2020). Diet or diet plus physical activity versus usual care in patients with newly diagnosed type 2 diabetes: the Early ACTID randomised controlled trial. The Lancet, 373(9678), 829–835. https://doi.org/10.1016/S0140-6736(09)60484-2
Inflammation is the body's natural way of healing, but when it becomes chronic and hidden, it quietly drives many of today's most common health problems—heart disease, diabetes, dementia, cancer, autoimmune conditions, and more. Unlike the redness and swelling from a cut or sprain, this “silent inflammation” often goes unnoticed while slowly damaging tissues and speeding up aging. Modern life fuels the fire: processed foods, food additives, pollution, plastics, chronic stress, too much sitting, and poor sleep. The good news is inflammation can be calmed by simple daily choices—eating colorful whole foods like berries, leafy greens, beans, nuts, seeds, and omega-3 rich fish; adding herbs and spices like turmeric and cumin; moving regularly; practicing relaxation; and repairing gut health. Even small shifts, like climbing stairs, eating within a shorter window, or reducing sugar, can make a big difference. By lowering inflammation, the body finds balance again, opening the door to more energy, resilience, and healthy aging. In this episode, I discuss, along with Dr. Shilpa Ravella and Dr. David Furman, why it's important to be aware of systemic inflammation and how to address it. Dr. Ravella is a gastroenterologist and Assistant Professor of Medicine at Columbia University Medical Center. She is the author of A Silent Fire: The Story of Inflammation, Diet & Disease, which investigates inflammation—the hidden force at the heart of modern disease. Her writing has appeared in The Atlantic, New York Magazine, The Wall Street Journal, TIME, Slate, Discover, and USA Today, among other publications. Dr. David Furman is Associate Professor and Director of the Bioinformatics Core at the Buck Institute for Research on Aging, as well as the Director of the Stanford 1000 Immunomes Project. He obtained his doctoral degree in immunology from the School of Medicine, University of Buenos Aires, Argentina, for his work on cancer immune-surveillance. During his postdoctoral training at the Stanford School of Medicine, Dr. Furman focused on the application of advanced analytics to study the aging of the immune system in humans. He has published nearly thirty scientific articles in top-tier journals such as Cell, Nature Medicine, PNAS, The Lancet, and others. This episode is brought to you by BIOptimizers. Head to bioptimizers.com/hyman and use code HYMAN to save 15%. Full-length episodes can be found here:What Causes Inflammation And How Can You Treat It? The Silent Killer: Inflammation And Chronic Disease How Silent Inflammation Accelerates Aging
Ralph welcomes Ben Cohen (anti-war activist and ice cream entrepreneur) to discuss his new campaign, "Up in Arms," which advocates for a common-sense Pentagon budget. Then, Ralph speaks to Guardian columnist Arwa Mahdawi about her recent piece: "When will we finally admit: the Gaza death toll is higher than we've been told."Ben Cohen is an entrepreneur, philanthropist, and longtime anti-war activist. He is a co-founder of the ice cream company Ben & Jerry's and a prominent supporter of progressive causes. He is co-founder of Up In Arms, a public education and advocacy campaign pushing for a common-sense approach to military budgeting. In May of this year, Ben was arrested by Capitol Police after he interrupted Robert F. Kennedy Jr.'s testimony by screaming,”Congress kills poor kids in Gaza by buying bombs and pays for it by kicking kids off Medicaid.”We're up in arms because the government has taken the kindness, the heart, the soul of the American people and essentially replaced it with so many bombs that there's no rational use for them. They've turned us all into mass murderers.Ben CohenYou know, politicians starting from Reagan are fond of saying “a nuclear war cannot be won and must never be fought.” And then they turn around and spend $100 billion a year on a nuclear arsenal that's capable of blowing up the entire world several times over. So they say one thing and they do another. I mean, a nuclear arsenal capable of blowing up the entire world several times over? That's not deterrence. That's delusion.Ben CohenI just go back to the moral issue of our time, which is Gaza—two-thirds of the American people don't support continuing to arm Israel. And we need to make our politicians pay the price for continuing to arm Israel… We have a midterm election coming up. If your guy voted to continue to essentially facilitate the genocide, vote them out.Ben CohenWhen you have more money than is needed, you tend to invite corruption, cost overruns, machinery that doesn't work, and I would advise that you look into why the GAO and the Pentagon auditors are being asked to do fewer audits of the military budget. Because there's almost a direct correlation between throwing money at a government program (especially at that scale) and corruption. And corruption is understandable to everybody. It's the number one political issue all over the world, when the pollsters poll.Ralph NaderArwa Mahdawi is a columnist for the Guardian and author of Strong Female Lead: Lessons from Women in Power. Here is her recent piece on the genocide in Gaza: “When will we finally admit: the Gaza death toll is higher than we've been told” (The Guardian, August 8, 2025)To be fair, the New York Times, Washington Post, and Wall Street Journal have published some pretty devastating reports from their reporters in that area. They've put out some devastating features on what's going on [in Gaza], but it doesn't translate into editorial denunciation by these papers. And it doesn't translate into taking the next step and doing what they would do in other conflicts around the world where there isn't so much prejudice and domestic pressureRalph NaderI'm an opinion writer, but as journalists, you're always supposed to report facts. And the fact is: we have absolutely no idea how many people are dead in the Gaza Strip. But there are plenty of studies (which I reference in the article—one Lancet peer-reviewed study, one letter to the Lancet by a highly-respected scientist, one empirical study by Michael Spagat) which show that the death count is a lot higher. So I truly believe that unless you're saying “the official figure from the Ministry of Health is around 60,000 but studies show it is probably much higher,” then that's just journalistic malpractice.Arwa MahdawiI think there's just this instinct to believe that Palestinians are lying and Israelis are telling the truth. And it also goes back to…this isn't just Israel's war, this is America's war as well. And this desire to see America as the good guys—we're the good guys, the Palestinians are the bad guys. And to have this black-and-white narrative where, obviously, we're the good guys, you know, and so if the Palestinian narrative casts doubt on that, then it must be wrong.Arwa MahdawiI always suggest that people write to the media outlets and say that they want to see more Palestinian narratives, they want the media outlets to voice their concern that foreign reporters are not being let in, that more aid workers are not being let in, that pictures are not coming out.Arwa MahdawiThere are very few pictures coming out of the scale of this destruction in Gaza, but when you see the ones that do come out, it is very, very obvious that there are more than 60,000 people dead.But there seems to be this lack of curiosity with some of my peers. Why aren't they asking, “Why aren't we seeing more pictures?” There should be nonstop outrage that their press freedom is being stifled like this and so many Palestinian journalists are being slaughtered.Arwa MahdawiNews 8/22/25* Last Thursday, during an event in her Masscusetts congressional district, Congresswoman Katherine Clark – who holds the position of House Minority Whip, making her the number two Democrat in the House – called Israel's campaign in Gaza a “genocide,” per Axios. According to Zeteo, this makes Clark the 14th member of Congress to use the “g word.” Lest she be accused of bravery however, Clark quickly walked back her comments. In a statement to the Jewish News Syndicate, Clark said “last week, while attending an event in my district, I repeated the word ‘genocide' in response to a question…I want to be clear that I am not accusing Israel of genocide.” This incident illustrates the cross-cutting pressures facing Democratic Party leaders. This divide will be on the agenda again at the DNC meeting on August 26th, where among other issues, party leaders will vote on competing resolutions to lay out the Democrats' position on Gaza. Allison Minnerly, the progressive DNC delegate sponsoring the resolution to end arms shipments to Israel, is quoted saying “Our voters…are saying that they do not want U.S. dollars to enable further death and starvation anywhere across the world, particularly in Gaza…I don't think it should be a hard decision for us to say that clearly,” per the Intercept.* Even as Democrats wrestle with their position on Gaza, the politics are clearly shifting. The Reject AIPAC coalition has released a new statement saying that among Democrats, AIPAC is now a “toxic pariah.” As evidence of this, Reject AIPAC cites the fact that only 14 House Democrats attended the AIPAC-sponsored Israel trip this year. According to Mondoweiss, “In 2023, the lobbying group brought 24 House Dems to Israel over recess. In 2019, over 40 attended.” Reject AIPAC also cites the fact that Reps. Valerie Foushee and Maxine Dexter, both recipients of millions of AIPAC dollars, voted to block arms to Israel and Foushee is even now rejecting AIPAC money. As these small victories mount, the horizon of possibility for movement within the party grows ever wider.* Last week, Tom Artiom Alexandrovich – a senior department head in Israel's National Cyber Directorate – was arrested in a “multi-agency operation targeting child sex predators,” in Clark County, Nevada according to the Las Vegas Metropolitan Police Department. According to Reuters, “Alexandrovich faces a felony charge of luring or attempting to lure a child or mentally ill person to commit a sex act ‘with use of computer technology.'” Yet, inexplicably, Alexandrovich was released by U.S. authorities and is back in Israel. This set off a firestorm in the U.S., with many accusing the Trump administration of facilitating Alexandrovich's release. The State Department was forced to issue a statement denying these claims, stating that Alexandrovich "did not claim diplomatic immunity and was released by a state judge…Any claims that the U.S. government intervened are false." The AP adds that the “Israeli Embassy in Washington and the Israeli Prime Minister's Office did not immediately return messages.” Disturbingly, the mainstream media seems to be purposely ignoring this case. While it has been covered by the Guardian, the Times of Israel, and Haaretz, there has been zero coverage in the New York Times or Washington Post, or ABC, NBC, or CBS. This media blackout adds fuel to the speculation that this case is being tamped down by the administration for political reasons.* Another troubling story regarding minors on the internet comes to us from Mark Zuckerberg's Meta AI. According to Reuters, internal documents from Meta Platforms detail “policies on chatbot behavior…[permitting] the company's artificial intelligence creations to ‘engage a child in conversations that are romantic or sensual,' generate false medical information and help users argue that Black people are ‘dumber than white people.'” Former Federal Trade Commission Chair Lina Khan called these reports “disturbing” and cited a legal complaint filed by the FTC to the Justice Department against Snap in January, under her leadership, “charging that [Snap's] AI chatbot was creating risks and harms for young users.” Khan noted that the “DOJ hasn't filed the case or taken any steps to protect these kids,” and demanded that “Any lawmaker concerned about big tech's abuse of kids should ask what is going on.” The administration's lack of action on these issues indicates that despite their rhetorical inveighing against the tech industry, they are treating SIlicon Valley with the same kid gloves they use for the rest of corporate America, even when it affects minors.* In more positive news from abroad, the Washington Post reports that between 2022 and 2024, Mexico lifted a stunning 8.3 million residents out of poverty. This 18% drop in poverty includes a 23% decrease in extreme poverty and a 16% drop in moderate poverty. According to experts, this remarkable achievement is the result of the policies of former President Andres Manuel Lopez Obrador, or AMLO, and his successor Claudia Sheinbaum, such as tripling the minimum wage and instituting a raft of social programs to aid “senior citizens, unemployed youth, students, farmers and people with disabilities.” President Sheinbaum is now plowing ahead with a new project – producing a “small, 100% electric, accessible [EV],” called the “Olinia,” to be fully manufactured and assembled in Mexico, per Mexico News Daily.* Turning to domestic politics, Congresswoman Elise Stefanik finally showed up in her district on Monday after an extended period of avoiding public appearances. At a ceremony honoring a late Clinton County clerk in Plattsburgh, Stefanik was drowned out by cries of “‘You sold us out!', ‘Shame!', and ‘Unseal the Epstein files!', along with a “steady stream of boos,” according to the Daily Beast. Stefanik “left the podium after speaking for less than a minute,” and when she returned, she was booed again. Stefanik's chronic absence and chilly reception is a bad sign for her gubernatorial aspirations. In the months since she has held a town hall, her constituents held a mock town hall where they addressed an empty chair, per WRGB, and New York Democrats AOC and Paul Tonko held town halls in her district, per the Albany Times-Union.* In more political news from New York, disgraced former Governor Andrew Cuomo is explicitly seeking to woo New York Republicans in his independent bid for Mayor of New York City. POLITICO reports that at a fundraiser at media mogul Jimmy Finkelstein's Southampton estate, Cuomo told the crowd that he agrees with President Trump that the “goal is to stop Mamdani.” To this end, he is trying to convince Republicans that they would be “wasting [their] vote on [Curtis] Sliwa,” the Republican nominee for Mayor, “because he'll never be a serious candidate.” Cuomo also implied that he is open to an alliance with Trump, telling the crowd “Let's put it this way: I knew the president very well.” Dora Pekec, a spokesperson for the Zohran campaign, is quoted saying “Since he's too afraid to say it to New Yorkers' faces, we'll make it clear: Andrew Cuomo IS Donald Trump's choice for mayor.”* In Texas, state Democrats have returned to the state, ending their attempt to defeat Governor Abbott's mid-decade redistricting scheme by denying the legislature a quorum. In a statement Gene Wu, chairman of the Texas House Democratic Caucus, said "We killed the corrupt special session, withstood unprecedented surveillance and intimidation, and rallied Democrats nationwide to join this existential fight for fair representation — reshaping the entire 2026 landscape," per the BBC. The legislature is now expected to approve the redrawn congressional maps; the state Democrats plan to continue fighting them in the courts. California has vowed to redraw their own maps to compensate for the expected loss of five Democrat-held seats in Texas. New York, New Jersey, New Hampshire and Maryland are also considering their own redistricting plans. Vice President JD Vance was deployed to Indiana to pressure Republicans in that state to redraw their maps to favor Republicans as well, per the IndyStar. It is a sad state of affairs that American politics has been reduced to such naked power grabbing plots, but here we are.* In local news, the federal occupation of Washington, D.C. continues to deepen. CBS reports the governors of at least six Republican-led states are sending contingents from their National Guards to the capital. These include Mississippi and Louisiana, West Virginia, South Carolina, Ohio and Tennessee. Just what these troops will do in Washington remains unclear. Tennessee Governor Bill Lee, who is sending 160 troops, cited “monument security” and “traffic control” among their official responsibilities. The federal agents on the ground, with little to do – the DOJ itself reports as violent crime is at a 30-year low in the District – seem to be mostly just harassing residents. The Daily Beast reports ICE tore down a banner and replaced it with a dildo. A local, Amanda Moore, posted a photo of 15 federal agents calling an ambulance for a drunk girl in Dupont Circle. And, while the Lever reports D.C. corporate lobbyists pushed for the occupation, it is wreaking havoc on local businesses; Rolling Stone reports reservations at D.C. restaurants are down between 25 and 31%, to take just one example. We can only hope that this pointless, destructive farce of quasi-fascistic political theater ends sooner rather than later.* Finally, investigative reporter and Iraq war veteran Seth Harp is out with a new book – The Fort Bragg Cartel: Drug Trafficking and Murder in the Special Forces – which details the double murder of Master Sergeant Billy Lavigne and Chief Warrant Officer Timothy Dumas, along with the “many more unexplained deaths…other murders connected to drug trafficking in elite units, and dozens of fatal overdoses,” at Fort Bragg in North Carolina. Among other remarkable discoveries, Harp “describes a U.S. special forces k9 [unit] that was given titanium dentures and encouraged to feast on human brains in the field,” in the words of publisher and producer Chris Wade. Remember these titanium dentures whenever you hear that there is no money to pay for critical social programs. The money is there. The political will is not.This has been Francesco DeSantis, with In Case You Haven't Heard. Get full access to Ralph Nader Radio Hour at www.ralphnaderradiohour.com/subscribe