Podcasts about enucleation

Send us a textIn this episode, Robyn Stewart, the county extension coordinator for the Northwest District for the University of Georgia Extension Service, shares the story of Web and his journey through losing his eye.  We talk about how Web adapted, and how Robyn made the tough decision to remove his eye.

In this episode of the Eye Believe Podcast, we delve into the topic of eye enucleation, offering a detailed guide on how to prepare for this significant medical procedure. We cover: An overview of eye enucleation Essential pre-surgery steps The surgical process explained Tips for post-operative care and recovery Emotional and psychological support resources Whether you are undergoing this surgery or supporting someone who is, this episode provides valuable insights and practical advice to help you through the process.

AUA2024: Surgical Laser Enucleation of the Prostate Guests: Amy Krambeck, MD and Mark Assmus, MD Outline: Segment #1: Why Enucleation Segment #2: What makes this course special? Segment #3: What is new this year compared to last year? Segment #4: What do you think makes this course unique? Segment #5: Who is the ideal participant?

Show Notes: The Perverted World Order addressed by The Hebrew Apostle Paul to the Romans Ch. 1. (Analysis). Please support the [Show] and its [Research] with Donations, please send all funds and gifts to :$aigner2019 (cashapp) or https://www.paypal.me/Aigner2019 or Zelle (1-617-821-3168).}

In this podcast Dr Sasha Vereecken describes and evaluates the randomised trial of holmium laser vs thulium laser vs bipolar enucleation of large prostate gland. (https://bjui-journals.onlinelibrary.wiley.com/doi/10.1111/bju.16174) The aim of the trial is to compare the outcome and morbidity of bipolar transurethral enucleation of the prostate (B-TUEP) and thulium laser enucleation of the prostate (ThuLEP) with those of holmium laser enucleation of the prostate (HoLEP) in the treatment of large symptomatic benign prostatic obstruction (BPO) through a non-inferiority randomised controlled trial (NCT03916536).

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.07.21.549990v1?rss=1 Authors: Fujii, K., Kondo, T., Kimura, A. Abstract: The centrosome is a major microtubule-organizing center in animal cells. The intracellular positioning of the centrosomes is important for proper cellular function. One of the features of centrosome positioning is the spacing between centrosomes. The spacing activity is mediated by microtubules extending from the centrosomes; however, the underlying mechanisms are not fully understood. To characterize the spacing activity in the Caenorhabditis elegans embryo, a genetic setup was developed to produce enucleated embryos. The centrosome duplicated multiple times in the enucleated embryo, which enabled us to characterize the chromosome-independent spacing activity between sister and non-sister centrosome pairs. We knocked down genes in the enucleated embryo and found that the timely spacing was dependent on cytoplasmic dynein. Based on these results, we propose a stoichiometric model of cortical and cytoplasmic pulling forces for the spacing between centrosomes. We also found a dynein-independent but non-muscle myosin II-dependent movement of the centrosomes in a later cell cycle phase. The dynein-dependent spacing mechanisms for positioning the centrosomes revealed in this study is likely functioning in the cell with nucleus and chromosomes, including the processes of centrosome separation and spindle elongation. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

This week Dr. Massnick continues discussing Enucleation and the Texas Eye Ball Killer. 

In this episode, host Alyssa Watson, DVM, welcomes back DJ Haeussler Jr, DVM, MS, DACVO, to talk about his recent Clinician's Brief article, “Transpalpebral Enucleation in Cats & Dogs.” Dr. Haeussler discusses the common indications for enucleation, some of the typical complications, and different approaches. Then, he dives deeper into the details of the transpalpebral approach, sharing many helpful tips along the way.Resource:https://www.cliniciansbrief.com/article/transpalpebral-enucleation-cats-dogsContact us:Podcast@briefmedia.comWhere to find us:Youtube.com/@clinicians_briefCliniciansbrief.com/podcastsFacebook.com/clinciansbriefTwitter: @cliniciansbriefInstagram: @clinicians.briefThe Team:Alyssa Watson, DVM - HostAlexis Ussery - Producer & Multimedia Specialist

This week Dr. Massnick starts her journey into the world of Enucleation. 

Join A Cure in Sight host, Danet Peterson, as well as 3 other omies for "Enucleation 101," part 2 of a 2 part episode release covering the varying experiences of enucleation of 3 more patients, their tips for recovery, as well as their insights on the process as a whole. Discussion of the prosthetic eye is not covered but we have plans to cover an ocularist and a panel of adjusting to the experience of having a prosthetic eye. Panelists featured:  Julie LeBlanc Lindsay (lind-SAY) Brown Kristen MacDonald Please share these 2 episodes with anyone considering Enucleation as a treatment path and be sure to subscribe to our podcast and newsletter to stay up to date! ANNOUNCEMENTS: 5K SITES ARE OPEN FOR REGISTRATION NEAR YOU! May 20, Raleigh, NC https://bit.ly/3KnyTwp May 21, Washington DC https://bit.ly/3ZotGIZ June 10, Minneapolis, MN https://bit.ly/3o5Mwr2 June 11, Philly, PA https://bit.ly/3U4hsUH July 8, Seattle, WA https://bit.ly/3TTgvP3 July 15, Palo Alto, CA https://bit.ly/3lRFi9D August 6, NYC/Brooklyn/Jersey area https://bit.ly/40KUtQH   Head to our site to register for a 5K Lookin' for a Cure near you for the remainder of the year!! www.lookinforacure.org   Swing for Sight April 22, 2023 REGISTER for SWING FOR SIGHT TODAY: Subscribe to the newsletter to stay in the know Newsletter link   Email contact@acureinsight.org for questions regarding any upcoming events! ********* Be sure to follow us on Facebook, Twitter, Linked In, or  Instagram @acureinsight, for more stories, tips, research news, and ideas to help you navigate this journey with OM! *A Cure in Sight is a 501c3 organization. All donations made can help fund our podcast to educate patients, fund research, aid patients, and more! Donate $10 $15 $20 today to help A Cure in Sight in their quest to find a cure. Contribute via  PAYPAL OR VENMO or reach out directly to contact@acureinsight.org  The Eye Believe Podcast is brought to you by Castle Biosciences. Castle Biosciences is a leading diagnostics company improving health through innovative tests that guide patient care. The Company aims to transform disease management by keeping people first: patients, clinicians, employees and investors.  This podcast was hosted by Danet Peterson and produced by Page Fronczek.

Join A Cure in Sight host, Danet Peterson, as well as 3 other omies for "Enucleation 101," part 1 of a 2 part episode release covering the varying experiences of enucleation of 4 patients, their tips for recovery, as well as their insights on the process as a whole. Discussion of the prosthetic eye is not covered but we have plans to cover an ocularist and a panel of adjusting to the experience of having a prosthetic eye. Panelists featured:  Clay Butler (primary enucleation) Wendy Carpenter (enucleation after recurrence) Danet Peterson (host) (enucleation after eye deterioration) Alison Benjamin (primary enucleation) ANNOUNCEMENTS: Head to our site to register for a 5K Lookin' for a Cure near you! www.lookinforacure.org   Swing for Sight April 22, 2023 REGISTER for SWING FOR SIGHT TODAY: Subscribe to the newsletter to stay in the know Newsletter link   Email contact@acureinsight.org for questions regarding any upcoming events! ********* Be sure to follow us on Facebook, Twitter, Linked In, or  Instagram @acureinsight, for more stories, tips, research news, and ideas to help you navigate this journey with OM! *A Cure in Sight is a 501c3 organization. All donations made can help fund our podcast to educate patients, fund research, aid patients, and more! Donate $10 $15 $20 today to help A Cure in Sight in their quest to find a cure. Contribute via  PAYPAL OR VENMO or reach out directly to contact@acureinsight.org  The Eye Believe Podcast is brought to you by Castle Biosciences. Castle Biosciences is a leading diagnostics company improving health through innovative tests that guide patient care. The Company aims to transform disease management by keeping people first: patients, clinicians, employees and investors.  This podcast was hosted by Danet Peterson and produced by Page Fronczek.

As a result of participation in this activity, participants should be able to:1. Describe the basics of BPH and Holmium laser enucleation of the prostate2. Explain the appropriate evaluation and patient selection for Holmium laser enucleation of the prostate3. Outline the Pro's and Con's of Holmium laser enucleation of the prostate

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2022.11.11.516158v1?rss=1 Authors: Colonnese, P., Phillips, M. A., Boley, N. C., Colonnese, M. T. Abstract: Early-life blindness causes lasting visual impairment, for which the circuit basis is only partially understood. Degradation of visual connections as well as the network dynamics supporting neural oscillations and arousal states are likely contributors. To define how blindness affects dynamics, we examined the effects of two forms of blindness, bilateral loss of retinal input (enucleation) and degradation of visual input (eyelid-suture), on emergent network properties and their state-dependence in the visual cortex of awake head-fixed mice. Neither form of early visual deprivation fundamentally altered the state-dependent regulation of firing-rates or local field potential oscillations. However, each form of deprivation did cause a unique set of changes in network behavior. Enucleation caused a loss of low-frequency synchronization specifically during movement, suggesting a mouse model for human alpha oscillations. Neurons were also less correlated and fired more regularly, with no change in mean firing rates. Chronic lid-suture decreased firing rates during quiet-wakefulness, but not during movement, and had no effect on neural correlations or firing regularity. Sutured animals also had a broadband increase in LFP power and increased occurrence, but reduced central frequency, of narrowband gamma oscillations. The complementary, rather than additive, effects of lid-suture vs.enucleation suggest that the development of these emergent network properties does not require vision but is plastic to modified input. Our results suggest that the etiology of human blindness will be a crucial determinant of circuit pathology and its capacity to respond to clinical interventions. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

Dr. Christine Lim is back talking about cat eyes. She has a great book with lots of cat pictures, the Small Animal Ophthalmic Atlas and Guide. We discuss what comfort level you should have treating eyes, how to do an enucleation, entropion, and infectious eye diseases.

In this episode I discuss the HOLEP (Holmium Laser Enucleation of the Prostate) with Dr. Andrew Bergersen.  The HOLEP procedures is used for men with very large, obstructive prostates causing urinary symptoms. You can find Dr. Bergersen at https://mnurology.com/physicians/andrew-bergersen/  Connect with me at  www.whyurologypodcast.com  

Amy Krambeck, MD, professor of Urology, discusses Holmium Laser Enucleation of the Prostate (HoLEP) for the treatment of lower urinary tract symptoms related to benign prostatic hyperplasia (BPH). She describes how HoLEP compares to other surgical BPH treatments and how MOSES-enabled pulsed laser modulation (MoLEP) advances the procedure.

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.11.02.365130v1?rss=1 Authors: Bhandari, A., Smith, J., Van Hook, M. Abstract: Within the nervous system, homeostatic mechanisms stabilize network activity following disruption by injury, disease, or degeneration. Vision loss and optic nerve injury in age-related diseases such as glaucoma might trigger homeostatic responses in direct retinal projection targets in the brain in adulthood. We tested this possibility using patch-clamp electrophysiology, optogenetics, and single-cell dendritic analysis to probe the effects of optic nerve injury and vision loss on dLGN thalamocortical (TC) relay neurons and their synaptic inputs following bilateral enucleation. Using vGlut2 immunostaining, we found that retinal axon terminals in the dLGN degenerated over several days post-enucleation, which corresponded with the loss of retinogeniculate (RG) synaptic function as assessed with optogenetic stimulation of ganglion cell axons in acute brain slices. Analysis of TC neuron dendritic structure from single-cell dye fills revealed a gradual loss of dendrites proximal to the soma, where TC neurons receive the bulk of RG inputs. Surprisingly, there was little change to the frequency of miniature post-synaptic currents (mEPSCs), even two weeks post-enucleation, although we did find an increase in the relative proportion of mEPSCs with slower kinetics, hinting at a possible enhancement of corticogeniculate input. Whole-cell current clamp recordings showed that enucleation enhanced TC neuron action potential firing and input resistance, consistent with homeostatic scaling of intrinsic neuronal excitability following perturbation of synaptic inputs. Our findings show that degeneration of the retinal axons/optic nerve and loss of RG synaptic inputs induces structural and functional changes in TC neurons consistent with compensatory homeostatic plasticity in the dLGN. Copy rights belong to original authors. Visit the link for more info

"This article presents an overview of retinoblastoma and enucleation and discusses the care and management of the unique patient population undergoing enucleation." Volume 111, Issue 1 [https://aornjournal.onlinelibrary.wiley.com/doi/full/10.1002/aorn.12896]

Dr. Timothy Chou of the State University of New York, Stoneyboork, discusses the only known case of eye penetration by an airsoft bb. Rangemaster Larry provides an update on SB 199 which has since passed the California Assembly Appropriations Committe. Rate the show on iTunes. See www.airsoftmedicine.com.

Dr. Timothy Chou of the State University of New York, Stoneyboork, discusses the only known case of eye penetration by an airsoft bb. Rangemaster Larry provides an update on SB 199 which has since passed the California Assembly Appropriations Committe. Rate the show on iTunes. See www.airsoftmedicine.com.

A conversation between Robert Goldberg, MD, and Mark Lucarelli, MD, during the Annual Fall Scientific Symposium of the American Society of Ophthalmic Plastic & Reconstructive Surgery (ASOPRS). Dr. Lucarelli and colleagues conducted an anonymous, online survey of ASOPRS members as well as a literature review to determine surgeons

Production of cloned transgenic rabbits from somatic nuclei was hampered since the nuclear transfer technique had extremely low rate of success. The objectives of the present study were to evaluate the developmental potential of cloned embryos from different types of donor cells and to produce cloned rabbits from cultured somatic cells. In vivo matured MII oocytes were treated with demecolcine to induce small cytoplasmic extrusion containing all maternal chromatin. Enucleation was carried out by the removal of the cytoplasmic extrusion. Various types of cells were used as nuclear donors. After electric pulses, embryonic blastomeres were introduced into enucleated oocyte cytoplasm having escaped from meiotic arrest by electric pulses followed by treatment with 6-DMAP/CHX. Nuclei from in vitro cultured cumulus cells (RCCs) and fetal fibroblast cells (RFFs) either grown to confluency or deprived of serum from the culture medium (starved-RFFs) or treated with sodium butyrate (NaBu-RFFs) were introduced into enucleated oocytes by electric pulses, and the reconstructed oocytes were activated by electric pulses followed by 6-DMAP/CB. The developmental potential of nuclear transfer embryos was assessed by the rates of in vitro blastocyst formation and in vivo development to term. The results showed that the chemically assisted enucleation protocol was successfully used with MII oocytes since high extrusion and enucleation rates were obtained. High cleavage rates were obtained in any type of nuclear donors (87% for embryonic blastomere, 78% for RCC, 93% for confluent RFF, 87% for starved-RFF, 95% for NaBu-RFF). However, higher blastocyst rates were obtained from embryonic blastomere and NaBu-RFF derived embryos (59% and 49%, respectively) than that from other type of somatic donors (RCC: 32.3%, confluent RFF: 33.1%, starved-RFF: 32.5%). When cloned embryos were transferred into pseudo-pregnant mothers, live offspring derived from embryonic blastomeres and day 27-fetuses derived from cultured RCCs were produced. No full-term development was achieved when RFFs were used as nuclear donors. Additionally, When 4-10-cell stage cloned embryos were aggregated with one or two blastomeres of 6-12-cell stage in vivo fertilized embryos, although a greater proportion of aggregated embryos developed to blastocysts as compared with cloned, non-aggregated embryos (78% vs. 61%, P0.05) and two of them developed to term, although the development to blastocyst was similar to that of cloned embryos (58% vs. 61%, P>0.05), and even lower than that of cloned-in vivo fertilized embryos (58% vs. 78%, P