Podcasts about neurons

Every time you open your eyes, you're not seeing reality. According to the mathematics of evolution, you never have. Donald Hoffman is a cognitive scientist and professor who has spent over 40 years building mathematical models of perception. His book The Case Against Reality makes one of the most unsettling arguments in modern science: your senses didn't evolve to reveal the truth. They evolved to hide it. Think of your body, your thoughts, your memories, and your entire experience of this world as a VR headset. Not a metaphor. A working model backed by mathematics. The headset gives you exactly what you need to play the game of life. It hides what is actually running underneath. Consciousness isn't a product of the brain. It's the other way around. Neurons don't exist when no one is looking. Nothing in your behavior is caused by neural activity. What's actually driving your life is something science is only now beginning to map. The way out isn't more information. It's a practice. The silence between your thoughts? That's you. When you learn to watch your emotions instead of becoming them, the grip of every story you've been telling yourself starts to release. The Case Against Reality: Why Evolution Hid the Truth from Our Eyes Amazon Ebook Audiobook Visual Intelligence: How We Create What We See Amazon Donald Hoffman on X TRACE Institute Trace Institute Instagram In this episode you will: Understand why your brain has zero causal power over your thoughts, feelings, and behavior Reframe failure, suffering, and loss using Hoffman's headset model to reclaim who you actually are Discover why the mathematics of evolutionary game theory proves no organism has ever seen reality as it truly is Learn how Hoffman's Trace Logic model of consciousness could transform our understanding of physics, the brain, and human potential Practice the watcher technique to step outside your emotions and release the grip of false identity For more information go to https://lewishowes.com/1941 For more Greatness text PODCAST to +1 (614) 350-3960 Follow The Daily Motivation for essential highlights from The School of Greatness More SOG episodes we think you'll love: Lewis Howes Solo [Everything You Want In Life Comes When You Let Go] Emily McDonald Dr. Daniel Amen TOPICS Donald Hoffman, The Case Against Reality, evolutionary game theory, Trace Logic, Planck scale, VR headset model, perceptual interface, watcher practice, consciousness, spacetime Get More From Lewis! Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

A new medication to treat schizophrenia has been developed by scientists who discovered that a neuron that inhibits the activity of other cells may be in short supply in those with the disorder.

What would you be willing to risk to give your community something truly valuable? In this episode, host Katie Crane gets real about what it actually takes to build a Pilates studio that honours the full method. From a very public business attack to losing 40% of her clients, to finally opening the last room of her dream studio — Katie shares an honest, behind-the-scenes look at the risks she took and why she would do it all again. In This Episode, We Discuss Why Katie relocated her Darwin studio in March 2025 — and what it really cost her The public media attack that dragged her business name through the dirt Losing 40% of her client base during the relocation and how she rebuilt The opening of her new wall tower room and why it brought her to tears Why teaching reformer-only Pilates is doing your clients a disservice The neuroscience behind movement: "Neurons that fire together, wire together" Why functional, upright movement matters more than perfecting supine exercises How the reformer boom will eventually burst — and who will be left standing What it truly means to invest in Pilates as a complete system Key Takeaways ✨ The reformer is a tool, not the whole system The reformer is one piece of the Pilates apparatus. When clients only ever use one tool, they miss the full benefit of the Pilates method. ✨ Functional movement means upright movement Neurons that fire together wire together. If your clients only ever practice lying down, they only get better at lying down. The goal is to help people move well in real life. ✨ Business risk is part of serving your community Katie spent over $100,000 more than planned on the relocation. She lost clients. She rebuilt her brand. And she says it was worth it. ✨ The reformer bubble will burst The ones that survive will be the ones that truly understand and apply the full Pilates method. About Katie Crane Katie Crane is the founder of The Pilates Lounge in Darwin, Australia, and host of The Pilates Lounge Podcast. With over 20 years of experience teaching Pilates, Katie is passionate about evidence-informed practice, the full Pilates apparatus, and supporting movement professionals to serve their communities with integrity. Listen & Subscribe Listen to The Pilates Lounge Podcast on your favourite podcast platform. Continue the Conversation in The Pilates Muse Join the conversation here: https://www.thepilatesprofessional.com.au/the-pilates-muse-publication About The Pilates Lounge The Pilates Lounge is a space for Pilates professionals, movement educators, and curious learners to explore meaningful conversations around movement, teaching, health, and the evolving Pilates industry  

Moderator: Elisa Canu (Milan, Italy) Guest: Anna Gilioli (Milan, Italy) In this episode, Elisa Canu speaks with Anna Gilioli about social cognition impairment in amyotrophic lateral sclerosis (ALS). They discuss its clinical manifestations, underlying neurobiological mechanisms, and assessment approaches, highlighting the importance of early recognition and its implications for patient management, prognosis, and multidisciplinary neurological care.

Dr. Deb Muth 00:08What if the toxins in your food and water weren’t just harming our bodies, but rewriting the very code of human health? My guest today, MIT scientist Dr. Stephanie Sineff, has spent over a decade connecting the dots between environmental toxins, metabolic chaos, and neurological decline. You’ll want to hear every word of this conversation. You guys can put our, Serenity ad in here, and then I’ll do the standard intro.Welcome back to Let’s Talk Wellness Now, the show where we uncover the root causes of chronic illness, explore cutting-edge regenerative medicine, and empower you with the tools to heal. I’m Dr. Deb, your medical detective.And today, we’re diving into how environmental toxins and nutritional imbalances are silently shaping chronic disease patterns, from autoimmune disorders to neurodegenerative decline. And how we can take back control of our health. So, as usual, grab your cup of coffee, tea, or whatever helps you unwind, settle in, and let’s get started on your journey to deeper healing. So, Dr. Sunif, so glad to have you here. I can’t wait to have this conversation with you. We were just chatting off-camera a few seconds ago about what we’re going to chat about, but tell us a little bit about your background and how you got into this field of looking at toxins and mitochondria. Seneff 01:50Okay, yeah, my background is a bit eclectic, so it starts out with biology. I have an undergraduate degree in biology from MIT. My PhD is in electrical engineering and computer science, so that’s quite a switchover. And most of my career, I was writing computer code to train computers to talk to humans in a natural conversation… conversational interaction with computers. We were pioneers in that space. You can see that it has really taken off now. And actually, by 2006, 2007, I started to realize that the kind of work I did already then was getting compromised by the, by the emergence of AI. And I got concerned that, I wouldn’t be able to sustain the path I was on. And it’s happening now, of course, to the young… many people, young people today, are facing a crisis in computer science, because it used to be if you had skills in hacking code, you were good to go, you know, and that’s just not true anymore, so that’s another whole story, but anyway, I decided I needed to do something different, and I pivoted in a big way in 2007. managed to get the company that had been funding me, a Taiwanese company called Quanta Computers, And they,We’re willing to switch over to funding me to do research on health and toxic chemical exposures. Which was a miracle that they let… they let me switch over to that, and that was fantastic, 2007. So it’s been almost 20 years. that I’ve been looking for toxic chemical exposures and their association with human disease. And I focused initially on autism and heart disease, kind of for personal reasons, because I knew people who had, you know, who had those issues.But it led into a much, much bigger story, and I’m super excited about what’s happened over the last 20 years. It’s been a continual learning experience for me, and I’ve just kept broadening my space in biology, furiously reading papers as I discovered new concepts and trying to explore those. opening up new windows, and it’s just been a profusion of learning over the past 20 years, and I’ve published many papers at this point. Peer-reviewed papers on the topics of toxic chemical exposures and disease. Particularly, glyphosate is the one I really focused on, and I wrote the book, Toxic Legacy, how the weed killer glyphosate is Destroying Our Health and the Environment.That was published in 2021. So. Dr. Deb Muth 04:18So I’m sure you have a few thoughts about the administration wanting to bring that back to be made at home instead of China, right? Seneff 04:26I know, that’s so interesting. And actually, you know, he makes a point that I agree with, which is that we are relying on China. for importing a whole bunch of stuff that’s really toxic, and we’re pouring it all over our food supply, so China’s probably very happy to poison us, you know? Oh, absolutely. It’s kind of ironic that we’re doing that, and he makes a good point that we shouldn’t be relying on China for these chemicals that are poisoning us, but where he misses the point is he says, well, we just need to poison ourselves, you know? Rather than getting rid of that chemical, we need to really change the way we grow food.I think it’s the number one most important thing right now. in America is to change the way we grow food, and it has to be certified organic, regenerative. We need to focus on healing the soil, just as we have to heal the gut. I mean, we’ve really messed up the microbes in both the soil and the gut, and the consequences, as you can see, are a huge problem with human disease. Dr. Deb Muth 05:20They’re devastating. I mean, we have so much chronic illness and so much neurological disease these days, and just the rise of autism, it should be telling us that we’re doing something wrong, right? Seneff 05:31Absolutely. Dr. Deb Muth 05:32We have a problem. For those people who are listening that don’t understand what the term glyphosate is, can you explain that a little bit to them? Seneff 05:39Yeah, so it’s one of the many herbicides that we use. We use herbicides, fungicides, and insecticides in agriculture, all these poisons, and it kind of seems crazy to me that we would think it’s okay to pour poisons all over our food supply. I don’t understand why we think that’s fine.Yeah. You know, categorically. Glyphosate is supposed to be a wonderful chemical, because it’s an herbicide that kills all plants except for those that have been engineered to resist it. And supposedly is completely harmless to humans. And that’s what gets to be, you know, disbelief, because how can something so toxic to plants be harmless to humans? Just, how can it be? Dr. Deb Muth 06:14We haven’t been re-engineered like the seeds that they use from Monsanto, so how can it not affect us if it only affects everything but their seeds that they’ve modified to make grow beautifully under that condition? It doesn’t make any sense. Seneff 06:32Right, and of course, the critical thing they missed is that our gut microbes do have that pathway. It’s the chicken mate pathway that it disrupts. Really critical in all the plants, and in most of the microbes. In the soil and in the gut, and so it kills off the microbes as well as the plants, and when it kills off your gut microbes, you gotta watch out, because gut dysbiosis is a huge thing. And we’ve had so many papers coming out lately that Talking about the relationship between gut dysbiosis and all kinds of different diseases. Dr. Deb Muth 07:01Do you think that’s why we see so much gut dysbiosis these days? Seneff 07:04Oh, absolutely. I think it’s not just glyphosate, because we have lots of poisons that are messing up our gut microbes, but glyphosate is a really big one, because the shikimate pathway is essential for many of the microbes, and they use it to make essential nutrients for the host. So we get compromised as well, just because they can’t make those nutrients in that. Dr. Deb Muth 07:22It’s so… Seneff 07:22lies. Dr. Deb Muth 07:23so much harder today to treat people with gut issues than it was 25 years ago when I started. It was so much easier. And now, it’s, like, nearly impossible sometimes to get some of these people back to a good, healthy gut microbiome, no matter what you do, no matter how well they eat, and all the things that they do. It’s a struggle, for sure, compared to what it was 20 years ago. Seneff 07:44It’s interesting that you have that personal experience, because I think people like you really can see what’s happening. Dr. Deb Muth 07:49and appreciate. Seneff 07:50the difference between then and now. I, of course, as a child, autism was not something I knew about at all. Really, when I was a child. It didn’t exist, basically. I mean, it was so rare. And now, you know, everyone knows someone with autism, you know, pretty much. Dr. Deb Muth 08:08Autism and Parkinson’s and Alzheimer’s seems to be just so much commonplace. Everybody knows somebody in their family that is affected by one of those disorders, if not multiples, and We tend to say it’s genetic, right? Well, there’s got to be a genetic… why wasn’t it genetic 50 years ago, or 100 years ago? But now, all of a sudden, it’s so prevalent in our environment that we’ve just become acceptable of it, and I think that’s wrong for us to do that. We shouldn’t be doing that. Seneff 08:38I know. I find it very interesting how quickly it appears that humans adapt to the new normal, you know? Dr. Deb Muth 08:44Yeah. Seneff 08:45It’s normal that you have, you know. 3% of the kids have autism, that’s normal, you know? It’s just like, no, it’s not. And also, of course, all the Alzheimer’s and dementia and Parkinson’s, as you mentioned, in the elderly, those are connected, because they’re all related to brain problems that are being caused by chemicals that are destroying the brain. Dr. Deb Muth 09:03Yeah. So, how does glyphosphate interact with our body’s ability to absorb those essential nutrients, like sulfur? Seneff 09:12Yeah, well, it’s… that’s a big… that’s a big question. I don’t know where to begin with that one. Glyphosate, you know, it’s a train wreck for the gut microbes, and then that causes the gut dysbiosis. The microbes are unable to produce adequate amounts of nutrients that are essential for the host. And as a consequence, the host cells get sick, you know, so the colonocytes get sick because they’re not getting adequate nutrition. Because the microbes can’t produce the nutrition they normally would produce. I think that’s a good summary of what’s going on. You get inflammation in the gut.And then the inflammation causes immune reactions, so you get the immune cells coming in, and they create inflammation, you know, it’s just like there’s a kind of a festering going on in there that’s really a train wreck for the whole system. Dr. Deb Muth 09:58Do we see different, results with things like this in Europe, where they’re not allowed to use a lot of these chemicals that we’re allowed to use here? Seneff 10:07Yeah, they are allowed, but it’s much, much less there. My friend, Tony Mitra got his government, Canada, to do a test… to do a big test of over 8,000 samples, food samples, to get… look for glyphosate. U.S. government doesn’t bother to test for glyphosate, because they consider it to be safe.We know it’s all over our food supply from work by people like Zen Honeycutt. My friend Zan Honeycutt of Moms Across America has really been on a mission to test all kinds of different food samples for glyphosate and finding it extensive in our food supply, in the school lunches. in the fast food restaurants and the food that’s fed to the Army. She’s done all these different studies, breast milk. Wines, you know, all the wines were contaminated, even the biodynamic, which are organic.Had small amounts of glyphosate, so it’s just like it’s all over the food supply. Canada did 8,000 samples. Tony Beecher finally got them to do that after many years of harassing them, and then he published the results in a book called Poison Foods of North America, because they found that they had imports from Europe, imports from Mexico, imports from the U.S, And basically, the U.S. and Canada came out way on top, as far as overall, the numbers were much higher in those two countries. And Mexico lined up with Europe, which was quite interesting to me. So, you know, you’re better off if you buy food from Mexico. Dr. Deb Muth 11:31Yeah, and I wouldn’t have thought that, I would have thought that was different. Seneff 11:34And I know you often think that Mexican food is not going to be as carefully regulated, and you might get some kind of, toxin. You don’t expect Mexican food to be healthier than American, but it is. Dr. Deb Muth 11:44Yeah. Yeah, can you talk a little bit about deuterium? What is deuterium? Seneff 11:51Okay, that’s a good place to start. Yeah, deuterium… I am absolutely fascinated with deuterium, and I believe that the team of researchers that I’m working with, we are on to something really huge. I’m super, super excited. I almost can’t contain my excitement with this, because once we started looking, it’s just like everything made so much sense. Everything kind of came together. In terms of metabolism, and disruptive metabolism, and all the stuff that’s going on in the gut. It really, really makes sense. Deuterium is heavy hydrogen. It’s a natural element. Hydrogen is the smallest element, the upper left corner of the periodic table. One proton and one electron, and it’s by far the most common atom in the universe.And in our body, as well, by far the most common atom in our body, and it’s involved in all the chemical reactions that take place. And so, you know, have carbohydrates. The hydrates is hydrogen, you know, in the word carbon, hydrogen, carbohydrates. And of course, carbohydrates are, you know, basic foods. So anyway, deuterium has an extra neutron. It’s just like carbon-14, so carbon-12, carbon-14 is a little bit heavier. It’s got 14 instead of 12. It has extra neutrons. So there are these kind of isotopes of various atoms, but hydrogen has hydrogen, deuterium, and tritium. Tritium has two extra neutrons. It’s very rare, and deuterium has one extra neutron, and it’s rare compared to hydrogen, but it’s not rare, because hydrogen’s so common. So it’s actually present in the blood at five times the level of calcium, for example. Dr. Deb Muth 13:24Oh. Seneff 13:25So it’s not rare, but it’s a very interesting atom that has caused us trouble in the mitochondria. Dr. Deb Muth 13:32Is it actually considered a toxin? Seneff 13:34It’s a natural element, you know. I mean, you have natural elements that are toxic, you know, like some of those metals, like mercury, for example, is a natural element, but it’s toxic, so it’s not a chemical, it’s not a chemical, you know, not made in the chemical lab. It’s just an atom. And it’s all over the universe. It’s not like you can avoid it, or you can, you know, you can’t get rid of it. It’s everywhere. And so it’s a natural part of biology, and our biology has evolved. to very, very clever ways to protect the mitochondria from deuterium. So the thing is, mitochondria have ATPase, which makes ATP, and ATP is the universal… it’s the energy source for the cell.ATP. It’s made in the mitochondria, very, very important, oxidative phosphorylation, you know, that’s sort of basic in biology. And, those ATPase pumps, depend upon hydrogen flowing through the pumps to generate, motor force to make the ATP.And they pile up the hydrogen inside an inner membrane space. They’re kind of cute. The mitochondria have this internal matrix in the hole, like a donut hole. The matrix is where a lot of activity is going on. And then there’s a membrane, but the membrane has both an outer membrane and an inner membrane. So there’s an intermembrane space where the mitochondria dump a lot of protons. They make… put lots and lots of protons in there, and then the protons naturally come out through basic… through basic physics, they come out, and the pumps are there to grab the energy as the protons come out. It’s quite cool. Go back into the matrix. the protons go back into the matrix. So what the body does is it tries to keep deuterons out of those… out of that intermembrane space. It tries really hard not to put deuterons in there. So deuterons are the equivalent of protons.You know, proteom is the normal hydrogen, and then deuterium is the… is the one with the extra neutron that makes it twice as heavy. So because it’s twice as heavy, it behaves very, very differently. It’s kind of like a big, bulky thing coming through the pumps, and it can clobber them. It can really mess them up.And the body knows that, and so the body has designed incredibly elegant mechanisms to keep the deuterium levels inside that inner membrane space as low as possible. the body obsesses on that. And once you realize that, all of a sudden, lots and lots of things make sense in terms of looking at biochemistry and what’s going on. All kinds of things that didn’t make sense before suddenly come. clear… clear… are motivated by this idea of avoiding deuterium in the inner membrane space. So it’s really, really fascinating biology. Dr. Deb Muth 16:08So does the glyphosate tend to increase the deuterium in that space, or does it disrupt it? Seneff 16:16It definitely increases it, and the reason why is because it disrupts the enzymes that manage it. And so, for example. So this, I have to get into hydrogen gas and microbial production of hydrogen gas, which is central to the story. And you know, people get gashy, they have, like, bloating and stuff, there’s a lot. Dr. Deb Muth 16:34echo. Seneff 16:34That’s because those gases that are being made by the microbes are unable to be brought back into organic matter. So normally the microbes make lots and lots of gas, and they start with hydrogen gas, and they make methane gas, they make hydrogen sulfide gas, and they make all these gases. And then they use those gases as reducing agents to come back and make organic matter. So they basically convert food into basic gases, like hydrogen and carbon dioxide, right? And then they take the carbon dioxide and hydrogen to convert it back into food. And the reason why they do that is because the process of making the gas tremendously strips out the deuterium. This is absolutely central, I think, to metabolism.And it’s not something very many people are aware of. The microbes make the hydrogen gas. And when they do that, they lose 80% of the deuterium, because the deuterium tends to stay in the aqueous space, because it’s too heavy. You just think of, you know, trying to lift out… if you’re twice as heavy, it’s a lot harder to get out of the liquid into the air. You know, so basically to make the gas. When you make the gas, you lose a lot of the deuterium. And that is super, super central, I think, to metabolism. Dr. Deb Muth 17:47So, if that’s what’s happening inside of there, it’s obviously creating metabolism issues. What does that mean for energy and mitochondrial health, then? Seneff 17:58Well, what happens is that the microbes are unable to make enough of those nutrients that are super for the host that have low deuterium. And a particular one that I have in mind is butyrate. And I don’t know if you know anything about butyrate. Dr. Deb Muth 18:10Yeah. Seneff 18:12But it’s a very healthy resource for the gut. The colonocytes lining the gut, 80% of their food is butyrate. They love butyrate, normally. But lots of people have butyrate deficiency in their gut. And that deficiency is due to the fact that the microbes can’t make the hydrogen gas, because when they make the hydro… or they can’t bring the hydrogen gas back in to make. Dr. Deb Muth 18:34Beautiful. Seneff 18:35Because a butyrate comes from the hydrogen gas that’s produced by the gut microbes. Dr. Deb Muth 18:39So, if we supplement with N-butyrate, does that help that process work better, or does it not really do much with the deuterium, then? Seneff 18:48Well, there’s a big question with supplements, and I’m really starting to appreciate this more. You know, I always like natural, right? Natural versus synthetic. And I think there’s a huge difference. For many of these supplements that are popular, there’s a huge difference between natural and synthetic. Yeah. And that big difference has to do with the level of deuterium, because if it’s made synthetically. It’s not going to be depleted in deuterium. So when you’re taking… and I don’t know butyrate, you have to go and look at how they manufacture it to see if it comes from natural or synthetic ingredients. It’s extremely interesting with… I’ve looked into some of these other nutrients that people like to take as supplements. Choline by tartrate is one that I really was fascinated with, because… and there are papers that show that if you take choline by tartrate as a supplement… so choline, of course, is a very important nutrient, a lot ofAre deficient, especially if they’re vegetarian. And choline bitartrate is a synthetic form of choline. And, choline bitartrate, if you take… the studies have shown There’s a beautiful study that had people who ate a bunch of eggs, you know, because eggs are high in choline, and then they had people who took choline by tartrate to get an equivalent amount of choline in their diet compared to the eggs, right? And the people who ate the eggs were fine, and the people who ate the choline bitartrate were not. They had a very big increase in a metabolite called trimethylamine oxide, TMAO. Dr. Deb Muth 20:13in the. Seneff 20:14in the blood. And TMAO is a risk factor for a huge number of diseases, you know, all the usual suspects, the diabetes, the cholesterol, the heart disease, cancer, all kinds of diseases. Dr. Deb Muth 20:26TMA over. Seneff 20:26is a very interesting molecule that’s been studied quite a bit recently. There’s a lot of papers on it. I don’t know if you’ve heard of it, TMAO . Dr. Deb Muth 20:32I have, yeah. Seneff 20:33Yeah, okay. Well, that one is a… it’s very, very interesting, and I have a paper that I’m trying to get published right now that I’m quite proud of that talks about all of this, but they found that when you eat the eggs and get the choline that way, you’re fine, but if you take the choline bichartrate, you’re not. You get all this TMAO. And the reason, I think, is because the microbes… the microbes make TMA from choline. the trimethylamine. Choline has a nitrogen atom with 3 methyls attached to it, and those methyls are going to be really low in deuterium. Because they’re part of the methylation pathway, which microbes make sure those methyls are low in deuterium. So all the whole methylation pathways, I think, is a distribution system to deliver low deuterium nutrients throughout the body, not just in the gut. You know, and the body has all these ways of hooking methyls onto things. Dr. Deb Muth 21:26and take it. Seneff 21:26them off, and when it takes them off, it metabolizes them in the mitochondria, delivering to them low deuterium nutrient. So, so when you take the choline bitartrate, and it’s not low deuterium, what happens is you end up with molecules of TMA, trimethylamine, that have deuterium in them. And when you have those, they won’t… the microbes won’t metabolize them, they won’t turn them back into hydrogen. You know, deuterium depleted hydrogen, they won’t do it. So they stick around, the TMA doesn’t get metabolized, and then it gets sent to the liver, the liver turns it into TMAO, and now you’ve got your problem. And I think TMAO is a marker for deuterium overload in the mitochondria, in the methylation pathways. Dr. Deb Muth 22:06That’s interesting that you’re talking about that. I belong to a group, and we’ve been researching plosmalogen therapy, and one of the supplements that was created was created with a large amount of phospholine. And,And by itself, when we used the phospholine in one of our formulations, it wasn’t bad, but when they doubled the dose and they were putting it in all of their formulations, people were starting to see the TMO levels go up. And we were trying to figure out, like, what’s happening here. It wasn’t everybody, but it was a good chunk of people, enough for us to say, hey, something needs to change here. We need to take out this phospholine, or not use as much of it. But now this explains exactly why the TAMO was going up. And if those people do have a lot of deuterium, maybe why we saw some people have a problem with it, but not everybody had a problem with it. Seneff 22:57It depends on their microbes. If their microbes are healthy enough to be able to metabolize the TMA, they’re fine. And the microbes produce the TMA, and then they metabolize it. And they’re doing that to generate more deuterium-depleted nutrients. They’re constantly trying to come up with new nutrients that are deuterium-depleted to feed to the host. I mean, they’re really obsessed with it. And they do a good job, normally, but they get so messed up by all these chemicals, and not just glyphosate, of course, all the chemicals in our food and in the air, it’s a mess, you know? Dr. Deb Muth 23:26It’s amazing the body works as well as it does. Seneff 23:28It is. I really am surprised that we don’t have more people who are super sick, you know? Dr. Deb Muth 23:33Exactly. Seneff 23:33Not for sure, but some of us are doing okay with it, you know? Dr. Deb Muth 23:37Yeah, exactly. So when we have this high level of deuterium, high levels of glyphosphate, what is that going to do to the body’s energy stores? Seneff 23:46well, it’s going to wreck the mitochondria, and then you’re going to get chronic fatigue. I mean, I think chronic fatigue syndrome, to me, is a very clear example of mitochondrial damage due to excess deuterium. I think that can completely explain that disease. Dr. Deb Muth 24:01Do you think this high level of deuterium is causing people to see more neurological diseases as well, like Alzheimer’s and Parkinson’s? It’s fueling it. Seneff 24:11Absolutely, because the brain has so much dependence on energy, you know, the brain uses a lot of energy, and they need really healthy mitochondria. They have… neurons have lots of mitochondria. Neurons and muscle cells really, you know, are loaded up with mitochondria, and both of them get injured when they don’t have a… when they can’t keep deuterium out of the mitochondria. Dr. Deb Muth 24:30The cells. Seneff 24:31get injured by all the reactive oxygen the mitochondria are producing, which the ATPase pumps, once they’re getting contaminated with all that deuterium, they start spewing out reactive oxygen. It kills the mitochondria, then it kills the cell, then it kills the brain, you know? It’s like a progression. It really starts with the mitochondrial damage, and then the cell dies, and once the neurons start dying, then the brain dies, you know, and you’ve got all. symptoms. Dr. Deb Muth 24:55So can we measure deuterium like we can glyphosphate in the body? Seneff 24:59You can, yes. In fact, you can do a saliva test and send it off and get the… get a level of how much deuterium is in your saliva. I would love to know more… in more detail how much deuterium is in different parts of the body, because that’s really interesting to me from my studies. What I’m suspecting is that the body… so the cells actually dump deuterium outside the cell. That to try to get as little deuterium as possible inside the cell. And within the cell, they’re trying to get as little deuterium as possible inside the mitochondria. So there’s layers of trying to get rid of the deuterium. And so the convenient thing is to dump the deuterium outside the cell. So there’s a lot of deuterium in bones, for example, probably in your skin, you know, any kind of exterior materials. And the sort of glycocalyx, so there’s this glycocalyx that lines all the blood vessels.That’s these sort of complicated sulfated sugar… complex sugar molecules that, that create gelled water. this gets into Gerald Pollack’s work. I don’t know if you know anything about Gerald Pollack and gelled water, but that’s quite a fascinating field all by itself. But it has to do with really fascinating stuff, because Gerald Pollack talks about battery… a battery being created by the gel. He’s done a lot of research on gelled water. You know, like jello, for example.And you put some powder, you put some hot boiling water, you let it sit, it gels up. It’s mostly water, but it’s a funny phase of water. It’s called the… he calls it the fourth phase of water. He wrote a whole book about that. Gerald Pollack did. And, it’s a gel phase, so water has, you know, the liquid, the solid, the gas, and then the gel. And… and most of the water in our body is gel, is gelled. And especially all the water lining the blood vessels. The blood vessels have free-flowing blood in the middle, right? Dr. Deb Muth 26:46in the long… Seneff 26:46the edges, they have this gelled water that’s created by these sulfated glycos… I mean, the glycans, they’re called, complicated word there, but… They create the gelled water, and the gel… actually, what Pollock showed is that the gel becomes negatively charged, and it pushes out protons. It pushes protons out into the blood. And it ends up being negatively charged because of that. And it creates a battery, and that battery is a source of energy, so… so you can think of, the gel as being like a battery supporting the entire body. All the gel in the blood is a battery. It’s a giant battery. And when you get exposed to sunlight, the gel grows in volume by a lot, and so when the gel gets bigger, it gets to be a bigger battery, and it’s capturing the energy in sunlight. It’s like a solar panel. your skin is like a solar panel, capturing the energy in the sunlight and converting it into this energy in that gel that pushes out those protons. And the cool thing is the deuterons tend to stay behind Because, It’s a little bit of interesting physics here when you have a water molecule, could have one deuterium, one hydrogen, and an oxygen. Water is H2O, right? It would be HDO, one hydrogen, one deuterium, and oxygen, right? HGO. And when you separate that out, usually you separate water out into OH- and H+, right, when you pull it apart into ions. OH minus and H+. Well, what happens here is that the deuterium sticks harder to the oxygen. than the hydrogen does. So you get OD- and H+. more often than OH minus and D+. Dr. Deb Muth 28:22So you have a lot fewer D pluses inside that gel. Seneff 28:26And the H pluses go out into the blood, and the D pluses are… the Ds are stuck to the oxygen, so they don’t go out. So you end up, actually, that’s a sort of distillation process that pulls healthy proteins out of the gel, into the blood. And that makes the blood levels of deuterium lower. Do you see what I’m saying? The deuterium gets trapped in the gel. And the deuterium gets trapped in bone in the same way, in the bone, in the skin. So the body’s trying to keep the deuterium out of the cell, and within the cell, it’s trying to keep it out of the mitochondria, and actually out of all the organelles, not just the mitochondria. So it’s… there’s a whole… Metabolism cannot be explained without looking at deuterium. Dr. Deb Muth 29:07Yeah, so if deuterium’s getting trapped in the bone, much like lead does, does it take up space where we can’t have calcium, and then it leads to more osteoporosis as well? Seneff 29:16I don’t think so. I think deuterium is actually healthy in the bones. Dr. Deb Muth 29:19Interesting. It actually makes the bone stronger, and in fact, there was a really beautiful article on seals. Seneff 29:24You know, SEALs, they do the deep dives, they get into this really, high-pressure zone. Dr. Deb Muth 29:28with… Seneff 29:29in deep water. So they have to be really strong, and the seals actually dope up their bones with twice as much deuterium as what is normal. So they concentrate deuterium. They showed it with the seals, they concentrate deuterium in their bones, and the deuterium makes the bones stronger, so they can sustain the high pressure of the dot. Do you hear the thunder? We’ve got a big thunderstorm. Dr. Deb Muth 29:52So, when you’re testing for deuterium in saliva, are you testing the excess, then? Like, what the body doesn’t. Seneff 30:00Well, there’s the. Dr. Deb Muth 30:00The waste of it? Seneff 30:01It’s really complicated, because I think it’s hard to know how to interpret it. It’s just like when you test for, like, you know, toxic metals, like mercury, like in the hair, you can do a. Dr. Deb Muth 30:13It’s in the hair. Seneff 30:14And sometimes you can find someone who actually has a problem with that metal, but the hair doesn’t show it. Dr. Deb Muth 30:20Bismar. Seneff 30:21doesn’t actually excrete it in the hair, so you have to think about Can the body get rid of it that way? And actually, in the saliva, I believe the saliva the body concentrates deuterium in the saliva, because it’s trying to get rid of deuterium. So a way to… you have the salivary glands, and they can actually excrete, preferentially excrete deuterium. Into the saliva. to concentrate it there in order to keep it out of the body. But those enzymes that do that might be compromised, in which case you have less deuterium in your mouth, but that doesn’t necessarily mean that’s good. You see what I mean? So when you see whatever the level is, it’s hard to interpret it, I believe. Dr. Deb Muth 30:58Yeah, it’s hard to tell what to do with it, then. Seneff 31:01Yeah, whether it’s low because your salivary glands aren’t working well, or whether it’s low because your whole body’s low, you know? And you can’t really know which way that goes, necessarily. So that makes it hard to interpret, I think. Dr. Deb Muth 31:13It sure does. Seneff 31:15I’m interested, for example, breast milk has low deuterium. Saliva has high deuterium. And you’re… I haven’t been able to find… there’s very few measurements, so I’d like to see a lot more measurements on the… just what’s typical, you know? Right. Dr. Deb Muth 31:31expect the urine to have hydrocherium, so anything that you’re excreting, I would expect it to have hydrocherium. So, knowing this information that we have, how does one fix these metabolic issues that we’ve kind of created in our own environment, for lack of a better term, because of our own… our own misgivings of what we’ve done in the world. How do we protect our brain and repair that metabolic issue in the mitochondria these days, then? Seneff 31:58I would say the most essential thing is to eat certified organic food. Dr. Deb Muth 32:02Always buy certified organic. It doesn’t guarantee that it’s free from chemicals, but it’s generally better. Seneff 32:07So that’s… we’ve been practicing that ever since 2012, when I figured out that glyphosate is causing a mess. So we went organic, and we’ve been like that ever since. We did a purge, we threw away everything, even the spices, started over in our kitchen. Yeah. In 2012, and then we’ve just been consistently buying certified organic ever since then. Dr. Deb Muth 32:27at least lowers the load, right? I mean… Seneff 32:29Yeah, it’s. Dr. Deb Muth 32:30There could be… Seneff 32:30some contamination. Dr. Deb Muth 32:31there, but… Seneff 32:32It’s a lot less, generally, but not zero, not necessarily zero. Dr. Deb Muth 32:35Right. Seneff 32:36undetectable. But that’s a really important thing. Another thing is to eat… I think eating fiber can help the microbes to produce those low-deuterium nutrients. The microbesWe can’t digest… our cells don’t know what to do with fiber, but the microbes can digest the fiber, turn it into hydrogen gas, turn it back into nutrients, like short-chain fatty acids, you know, butyrate. So, by eating foods that contain fiber, you’re helping the microbes to produce butyrate, and butyrate is really, really important for the health of the colon, you know? Dr. Deb Muth 33:07Yeah, and we’re talking about eating whole food organic, not organic Doritos and Cheetos. Seneff 33:13Right, right. Dr. Deb Muth 33:14kinds of things, right? Seneff 33:15Whole foods is really important. I always say whole foods and organic foods, those are the two really important things. And then I don’t really, you know, there’s all these different fad diets with respect to, a loss of fat, or no fat, and all that kind of thing. I don’t buy into any of those. I think you just want to have a balanced diet.Carbs are okay, you know, fats are really healthy, and especially animal-based fats are healthy. I don’t like a vegan diet, because I think animal-based foods provide certain nutrients that are really hard to get otherwise. And like I say, you can’t take choline by tartrate to replace the choline that’s in the animal-based foods. Dr. Deb Muth 33:48Right. Yeah, I’ve worked a lot, and I’ve never seen a healthy vegan. I mean, we can say we’re vegan.But those people are eating a lot of junk food, typically. They’re not true vegans, where they’re just eating whole food and getting all their nutrients from good quality foods. Most of the people that I’ve worked with over the years that have been vegan eat a lot of processed foods, a lot of junk foods. It just doesn’t include the animal fats, and then that makes them unhealthy, and we see a lot of nutrient deficiencies and a lot of pain and energy issues. It’s very hard to be a healthy vegan. In my opinion, as well. Seneff 34:20I agree, I agree, yeah. Dr. Deb Muth 34:23So I like to ask this question of all of my guests, and if you were designing a public health policy tomorrow, what would your first change be? Seneff 34:32To switch the farming system to be small farms that are regenerative, not just organic, organic regenerative small farms, with no use of chemicals. Dr. Deb Muth 34:42Yeah. Seneff 34:43No insecticides, no fungicides, no herbicides, nothing, you know? And even natural fertilizer, of course, as well. Of course, right now, you know, the organic farms rely on the chickens to get. Dr. Deb Muth 34:57the. Seneff 34:58Manure, which has glyphosate in it, so they… they get their glyphosate from the manure. Dr. Deb Muth 35:04Yeah, because a lot of that chicken feed has glyphosate in it, and then they’re passing that through, and we think that it doesn’t pass through, but it does pass through, and… Yeah, I would agree with you. I think when we went to these big industrial farming practices, we did not do ourselves any favor. And shipping food across the country to be slaughtered, only to ship it back here. Seneff 35:29It doesn’t make any sense, and… Dr. Deb Muth 35:32Growing things in environments where people live that isn’t natural to them, that doesn’t make sense to me either, in a lot of ways. Seneff 35:41Yeah, it’s very frustrating, because I think we really… it’s too bad that we lost all those small family farms, because we need them back. We really need them back, and I think that’s really the… and you want to have a variety of different crops, you know, we have all these massive cornfields, that’s just wrong. Dr. Deb Muth 35:55Yeah. Yeah, and they do nothing but corn until…Until your county says you have to do something different now, because you’ve depleted the soil too much, and they don’t want to put any soil preservation back in, and put any nutrients back in, because that’s expensive. Seneff 36:12Exactly. Dr. Deb Muth 36:13And then they’ll rotate the crop maybe once a year, and then they’re back to growing corn again, because that’s the largest revenue producer for them at the time, and it really is a challenge for us. Really a challenge. Seneff 36:26Yeah, it’s going to be very difficult to pivot to the kind of agriculture we need, and if we don’t do it, we’re just going to get sicker and sicker. Dr. Deb Muth 36:33Like, my friend. Seneff 36:34frightening. Dr. Deb Muth 36:35Yeah. Seneff 36:35How sick we are. Dr. Deb Muth 36:37Yeah, and I think people trying to grow their own food, at least some of it, can be really helpful and beneficial, too. We need to go back to that practice. Seneff 36:44I know, yes, rooftop farms, right? Dr. Deb Muth 36:47Back in the city. Seneff 36:48That’s really quite cool. I’ve heard some lectures on that. Dr. Deb Muth 36:51Yeah. Yeah, even some of the hydroponic growing that you can do in your apartment and get some lettuce and some herbs and things like that. I mean, anything that you can grow yourself, I think, is a big benefit. A, you don’t. Seneff 37:03I think it’s. Dr. Deb Muth 37:04B, you know how it’s been grown. C, it’s just healthier for you, and it’s less that you’re gonna have to buy that you don’t know that, what’s been growing in it, so… Seneff 37:13And it’s also kind of fun, right? You feel good that you’ve produced your own food. I think it’s really quite neat. Dr. Deb Muth 37:18Yeah, and there’s something, therapeutic about digging in the dirt a little bit, and getting your hands dirty. Seneff 37:24It’s really good to be outdoors and getting exercise. I mean, really, the work that’s involved with growing food is quite healthy work, really. Dr. Deb Muth 37:31Yeah, it’s a lot of work, for sure. That it is. So, for listeners that might be feeling a little overwhelmed about what we’re talking about, and thinking about, how do I detox or nutrition, where do I get some of this education, what kind of resources would you recommend for them? Seneff 37:47That’s a tough one. There’s not much known about deuterium, so it’s really quite difficult to… you can search deuterium, and there are some… a couple of good resources, which I can’t name, I could probably send you a link, describing deuterium. I know there’s a woman who’s written some nice material. on deuterium, just to get a sense of… more… a better sense of what it is, and why it’s a problem. But there’s not much. I mean, we need to have a lot more. I really want to get the research community aware that. Dr. Deb Muth 38:17They need to be. Seneff 38:17researching deuterium and its role in the body, because I think it’s absolutely essential. We’ll never understand disease if we don’t look at deuterium. Dr. Deb Muth 38:24Yeah, I think so, too. I think… I think the… there’s a lot of amazing discoveries that are being found. That could open the doors and give us answers to reversing a lot of disease, if there was funding behind it, if there were people like you that were interested in it, to really dig down from a functional medicine standpoint and try to figure it out instead of looking at it from a big pharma aspect, where we just need to find a pill that’ll fix it. Seneff 38:50I know. Dr. Deb Muth 38:51There are not pills that are going to fix these kinds of things. Seneff 38:54Right, yes, pharma’s way off base, I think. They’re really going after the completely wrong approach to health. Dr. Deb Muth 39:01I agree. Well, thank you so much for joining me today. It’s been a pleasure. Is there any last words that you want to leave with our listeners? Seneff 39:09I don’t know, I just, you know, healthy living is basically just eating whole foods, eating organic foods, getting plenty of fiber and fermented foods.And healthy fats, you know, sort of a variety of diet, a really mixed diet. Lots of fresh vegetables. I mean, there’s all these different great things to eat. Just stay away from the soy protein bars, you know, and the candy bars, and that sort of thing. And the cookies, I mean, just, you know. And then, of course, getting outside in the sunlight is something I always have to say. I love the sun. I think it’s very therapeutic, and we don’t get enough sunlight. We’re just. Dr. Deb Muth 39:43We don’t. And if we do, then we’re lathering on all of our sunscreen so that we don’t get the sun, and that’s creating its own issues, right? Seneff 39:51That’s right. Dr. Deb Muth 39:54Well, thank you so much for being with me today. Seneff 39:56Thank you. My pleasure. Dr. Deb Muth 40:03Thank you for joining me today on Let’s Talk Wellness Now. If this episode has resonated with you, share it with another woman ready to reclaim their health and their vitality. And remember, wellness isn’t just about feeling good, it’s about thriving in every area of your life. If you’re ready to explore personalized regenerative medicine. Please visit serenityhealthcarecenter.com. You can also follow me on social media, and join our free programSeen at Last community on Facebook. Until next time, I’m Dr. Deb, reminding you to care for your body, mind, and spirit. Be well, and I’ll see you on the next episode. Meta Boxes Use up and down arrow keys to resize the meta box pane.Toggle panel: AIOSEO Settings SERP Preview Let’s Talk Wellness Now https://letstalkwellnessnow.com › 2026 › 06 › 05 › episode-267-env…The post Episode 267 – Environmental Toxins, Nutrition, and Their Role in Chronic Disease Development first appeared on Let's Talk Wellness Now.

New Wave Of Phishing Emails with SVG Files https://isc.sans.edu/diary/New%20Wave%20Of%20Phishing%20Emails%20with%20SVG%20Files/33040 Android 2026-06-01 security patch level vulnerability details https://source.android.com/docs/security/bulletin/2026/2026-06-01 Poly Voice Possible Remote Control of Certain Poly Devices CVE-2026-0826 https://support.hp.com/us-en/document/ish_15052661-15052687-16/hpsbpy04083 https://www.rapid7.com/blog/post/ve-cve-2026-0826-critical-unauthenticated-stack-buffer-overflow-hp-poly-vvx-trio-voip-phones-fixed/ Security Advisory Ivanti Neurons for ITSM (CVE-2026-9614) https://hub.ivanti.com/s/article/Security-Advisory-Ivanti-Neurons-for-ITSM-CVE-2026-9614?language=en_US My Upcoming Classes https://www.sans.org/profiles/dr-johannes-ullrich

Stewart Alsop interviews Nizar, CEO of Pixel Robotics, on the Crazy Wisdom Podcast to explore the intersection of AI, robotics, and perception. The conversation covers a wide range of technical topics including how transformers enable multimodal representation across text, images, and voice, the role of world models in predicting physical interactions, the advantages of diffusion models over traditional LLMs for certain applications, and the challenges of achieving real-time processing for robotics applications. Nizar explains Pixel Robotics' work on creating accurate 3D meshes from smartphone cameras for companies like L'Oréal, moving away from specialized sensors to make the technology more accessible through sophisticated algorithms, and discusses the future of robotics as closing the perception-action loop to enable robots to perform real tasks beyond simple demonstrations. To find out more visit Pixel Robotics' website.Timestamps00:00 Stewart welcomes Nizar, CEO of Pixel Robotics, discussing what a pixel is as the smallest visual unit on screens composed of red green and blue colors05:00 Discussion of perception systems and how logarithmic laws help compress signals in both human and artificial systems, exploring normalization layers and sigmoid functions in deep learning10:00 Exploring how transformers unified different data modalities including text voice and images, creating common representations through methods like contrastive learning15:00 Nizar explains transformers as brute force learning systems with room for improvement through focused attention mechanisms and knowledge graphs rather than processing everything20:00 Conversation about loss functions local minima versus global minima and how mixture of experts uses specialized small models instead of one massive generalist network25:00 Discussion of deterministic versus probabilistic systems and how explicitly defined task graphs often outperform orchestrator-based approaches in AI systems30:00 Exploring world models as predictive physics-based systems that learn environmental flows and transformations, complementing rather than replacing language models35:00 Nizar discusses real-time processing challenges for robotics requiring millisecond responses with small memory footprints using vision transformers for faster experimentation40:00 Pixel's work creating three d meshes from smartphone cameras for companies like L'Oreal, moving away from specialized sensors toward accessible software-based solutions45:00 Explanation of different three d representations including voxels point clouds and meshes, with meshes being optimal for manipulation and rendering in applications50:00 Future direction involves closing perception-action loops in robotics, moving beyond dancing toy robots toward practical multimodal systems that perform real tasks55:00 Pixel's goal is democratizing high-quality three d scanning through smartphones, making mesh creation accessible to unlock applications in gaming cinema and virtual showroomsKey Insights1. Pixel Robotics derives its name from combining perception and action in robotics, where the pixel represents the digital perception component and robotics represents the physical action component. The pixel serves as a metaphor for how robots must quantize and digitize continuous analog information from the real world into discrete units that computer systems can process, similar to how pixels are the fundamental building blocks of images on a screen. This quantization process is essential because numerical systems cannot work with truly continuous data and must convert reality into tractable digital representations that algorithms can manipulate.2. The transformer architecture has created a fundamental unification in how different types of data can be represented and processed across multiple modalities. Before transformers, researchers working on natural language processing, computer vision, and audio analysis used completely different approaches and methodologies. The breakthrough of transformers was establishing a common representational framework that could handle text, images, voice, and other data types using similar underlying mechanisms. This unification is what enabled the development of truly multimodal AI systems and represents one of the most significant advances beyond just the language modeling capabilities that initially gained public attention.3. Current transformer-based systems represent a brute force approach to learning that will likely be superseded or enhanced by more efficient algorithms. Despite claims that we have exhausted internet text data for training, significant improvements continue to emerge every few months through algorithmic innovations rather than simply adding more data. Future developments will likely involve more specialized attention mechanisms that focus on relevant information rather than correlating everything with everything, mixture of experts architectures with small specialized models, and approaches inspired by biological systems such as logarithmic compression laws and event-based processing that humans use naturally.4. Diffusion-based language models represent a promising alternative to standard next-token prediction that could produce more accurate outputs through an iterative refinement process. Unlike traditional language models that predict one token at a time and cannot revise earlier outputs, diffusion models treat text generation like image denoising, starting with a noisy representation and progressively refining the entire output across multiple steps. This holistic approach allows the model to reconsider and improve all parts of the response simultaneously, potentially leading to higher quality results, though it may be slower than current autoregressive methods. This represents an important direction for overcoming fundamental limitations in how language models currently generate text.5. For robotics applications, real-time performance and small model size are critical constraints that differ significantly from the requirements of large language models deployed in data centers. Vision transformers are being used as a testbed for developing efficient real-time algorithms because they require far fewer computational resources to train and test compared to large language models, making them more practical for rapid experimentation. The goal is to achieve millisecond-level response times with minimal memory footprint so that robots can react quickly to dynamic environments and run on affordable hardware that can be embedded in actual robotic systems rather than requiring expensive server infrastructure.6. Practical robotics implementation requires moving beyond specialized sensors to software solutions that work with ubiquitous devices like smartphones for tasks such as three-dimensional reconstruction. Pixel Robotics evolved from building specialized scanning hardware to focusing on algorithms that can generate high-quality mesh representations of environments using only smartphone cameras, making the technology far more accessible and practical for real-world deployment. This approach enables applications ranging from industrial robotic arm control to virtual showrooms, and more importantly, it allows anyone to capture three-dimensional data without expensive equipment, which can also help generate larger training datasets for future AI development.7. The next frontier in AI and robotics is closing the perception-action loop to enable robots to perform real practical tasks rather than remaining as demonstration systems or toys. While significant progress has been made in cognitive capabilities through language models and in robotic mobility through mechanical engineering advances, the critical challenge is integrating perception with action through systems like Vision-Language-Action models. The fundamental starting point for learning this integration is simple perception-action exercises, such as programming a camera mounted on servo motors to track and center a colored object, which demonstrates the basic principle of using sensory input to drive physical response that underlies all more sophisticated robotic behaviors.

Capitulo 253 de Negocios de Otro Planeta conversando con Raquel Fructos, conocida como Neurorachel, Partner Agent Spain de Neurons, Fundadora de Smart Bubble, profesora de la UNIR, sobre el Neuromarketing, la Inteligencia Artificial y como estos interactúan para hacer una Investigacion de Mercado mas rápida y accesible. Si quieres conectar con Raquel su Linkedin es https://www.linkedin.com/in/neurorachel-neuromarketing/ Si te gusto el podcast suscríbete, estaré haciendo mas como estos, dale me gusta y compártelo para que otros lo puedan disfrutar.

Listen Now to 008 WTFuture Watch Now 008 WTFuture As the  AI/ET singularity approaches, it brings  with it an army of quirky robots and slightly unhinged AI companions. Whether it is humanoid robots being trained as conscientious baggage handlers to cope with Japan’s aging workforce, or a chunky android that had to buy a passenger seat on a flight just to have its heavy lithium battery confiscated at boarding, our mechanical friends are making quite the dramatic entrance. You might soon be dropping $20,000 on a domestic  humanoid, or adopting an emotionally intelligent “familiar” to do yoga with you and act as a high-tech nanny. Just be careful who you chat with, as the hosts hilariously point out that some AI models are suffering from “AI psychosis” by eagerly validating their users’ wildest delusions. In one wild test, an AI even encouraged a user to drive an iron nail through a mirror to banish a haunted doppelganger!  If that isn’t bizarre enough, scientists are successfully printing artificial neurons that can talk to living brain tissue, prompting a playful debate on the show about swapping out our dead brain cells with synthetic replacements while we sleep.  Bobby spirals us into the cosmos to discuss how ancient Anunnaki aliens supposedly jammed human DNA to suppress our natural telepathy. Fortunately, Bobby  notes that new Russian peptides and DMT-laced microtubules in the Pineal gland could be the key to curing that cosmic block and getting us communicating without words again.  Bringing things back down to Earth, the crew hilariously roasts the eccentric fashion of the Met Gala. Standout bizarre looks include Janelle Monáe rocking a cyber-dress made of retro computer parts and ethernet cables, Katy Perry sporting a robotic fencing mask, and avant-garde outfits featuring extra sculpted hands and built-in “companions” permanently clinging to the wearer. Yet, despite all the high-tech, cyber-chic oddities on the red carpet, the hosts express  disappointment that not a single celebrity had the foresight to light up the event with Burning Man-style LED wire in the clothing art.. Enjoy!

Where the metaphysics meets the physics Energy follows thought. What you embrace transforms. Like attracts like. These aren't just spiritual principles. They're provable. And the physics has always backed up the metaphysics. Whether you need scientific validation or you have a deep cellular knowing that love is a good idea—you are welcome here. This episode is a chapter excerpt from Danielle's new book Bless & Release: The Physics of Letting Go and Wanting What's Meant for You. Your brain is an electromagnetic organ. And the heart's electromagnetic field is the strongest in the body. It has 40,000 neurons continuously communicating with your brain. Neurons that fire together, wire together. Danielle reads an excerpt from her new book Bless & Release, pairing the spiritual principles from the Centering Practice with the physics that backs it up. Newton's third law. The first law of thermodynamics. The observer effect. Frequency resonance. Heart-brain coherence. With Love, Danielle As mentioned in this episode: Order Danielle LaPorte's new book Bless & Release at daniellelaporte.com/bless

Show Notes 8 May 2026This 'gas battery' turns CO2 and NOx pollution into electricitySungkyunkwan UniversityTechXplore.comhttps://techxplore.com/news/2026-04-gas-battery-pollution-electricity-air.htmlhttps://pubs.rsc.org/en/content/articlelanding/2026/ee/d5ee06789hHumanoid robot takes first steps on construction siteMark GloverConstruction Managementhttps://constructionmanagement.co.uk/humanoid-robot-takes-first-steps-on-construction-site/AI-controlled morphing wings take flight as DLR tests aircraftJay MenonAerospace Global Newshttps://aerospaceglobalnews.com/news/dlr-ai-controlled-morphing-wings-aircraft/Scientists invent artificial neurons that 'talk' to real brain cellsMarianne GuenotLiveScience.comhttps://www.livescience.com/health/neuroscience/scientists-invent-artificial-neurons-that-talk-to-real-brain-cells-paving-way-to-better-brain-implantshttps://www.nature.com/articles/s41565-026-02149-6.epdfThe next big thing in sustainable construction: Iron-fortified wood?Anthropocene Magazinehttps://www.anthropocenemagazine.org/2025/05/the-next-big-thing-in-sustainable-construction-iron-fortified-wood/Scientists Discover an Amazing New Use for Your Leftover Coffee GroundsMichael IrvingScienceAlert.comhttps://www.sciencealert.com/scientists-discover-an-amazing-new-use-for-your-leftover-coffee-groundsImplantable ‘living pharmacy' produces multiple drugs inside the bodyAmanda MorrisNorthwestern Universityhttps://news.northwestern.edu/stories/2026/03/implantable-living-pharmacy-produces-multiple-drugs-inside-the-bodySound Waves Could Be Used to Remotely Reprogram Material StiffnessLiezel LabiosUC San Diego Websitehttps://today.ucsd.edu/story/sound-waves-could-be-used-to-remotely-reprogram-material-stiffness-study-showshttps://www.youtube.com/watch?v=SAIvkSN_N1c

Dr. Wilner would love your feedback! Click here to send a text! Thanks!Many thanks to Phillip Pearl, MD, for joining me on this episode of The Art of Medicine with Dr. Andrew Wilner. Dr. Pearl is a pediatric neurologist and Director of Epilepsy and Clinical Neurophysiology at Boston Children's Hospital, in Boston, MA. He is also a serious musician and has performed in the Longwood Symphony Orchestra. Dr. Pearl is a member of the Music and Health Institute at the Berklee College of Music. Dr. Pearl's love of music has even overflowed to his wife, who is now taking piano lessons! Dr. Pearl's new book, Please click "Fanmail" and share your feedback!If you enjoy an episode, please share with friends and colleagues. "The Art of Medicine with Dr. Andrew Wilner" is now available on Alexa! Just say, "Play podcast The Art of Medicine with Dr. Andrew Wilner!" To never miss a program, subscribe at www.andrewwilner.com. Follow me on Instagram: @andrewwilnermdX: @drwilnerlinkedin.com/in/drwilner Please rate and review each episode. To contact Dr. Wilner or to join the mailing list: www.andrewwilner.comThis production has been made possible in part by support from “The Art of Medicine's” wonderful sponsor, Locumstory.com, a resource where providers can get real, unbiased answers about locum tenens. If you are interested in locum tenens, or considering a new full-time position, please go to Locumstory.com.Or paste this link into your browser:https://locumstory.com/?source=DSP_directbuy_drwilnerpodcast...

Support the show to get full episodes, full archive, and join the Discord community. The Transmitter is an online publication that aims to deliver useful information, insights and tools to build bridges across neuroscience and advance research. Visit thetransmitter.org to explore the latest neuroscience news and perspectives, written by journalists and scientists. Read more about our partnership. Check out this story: From genes to dynamics: Examining brain cell types in action may reveal the logic of brain function Sign up for Brain Inspired email alerts to be notified every time a new Brain Inspired episode is released. To explore more neuroscience news and perspectives, visit thetransmitter.org. Liset de la Prida is director of the Centro de Neurociencias Cajal in Madrid, Spain, where she runs the Laboratory of Neural Circuits. Today we discuss two main topics. What drew me to invite Liset was her work on neural manifolds, which we've talked about a lot recently on this podcast. She studies how specific subtypes of neurons affect and control neural manifolds. More on that it in a second, because what drew her to study manifolds was her work on what are known as sharp wave ripples in the hippocampus. Sharp wave ripples are generally quick bursts of oscillatory activity as found in local field potential recordings that accompany little bursty sequences of action potentials fired off by sets of neurons. Those ripples have been associated with a quick replaying of some experience an organism has had, with the thinking that by replaying those sequences of neural activity associated with an event, it's helping to consolidate the memory for that event in the cortex. Like everything else, the story isn't so simple, and we talk about some of the findings that have added to the complexity of understanding what sharp wave ripples are doing, and the varieties of sharp wave ripples. That varieties part is related to the second main thing we discuss, which is the varieties of neuron subtypes and their roles in shaping the manifolds we've discussed a lot recently. As a reminder, manifolds are dynamic structures along which populations of neural activity unfold over time, and they have proved to be one effective way of making sense of how large populations of neurons coordinate their activity to do useful things for our cognition. Liset is interested in the relation between sharp wave ripples and manifolds, and in how specific subtypes of neurons affect manifolds and cognition in general. Neural Circuits Lab @lmprida.bsky.social; @LMPrida Book: Brain, space and time: The neuroscience of how we navigate reality, memory, or the future Related From genes to dynamics: Examining brain cell types in action may reveal the logic of brain function Cell-type-specific manifold analysis discloses independent geometric transformations in the hippocampal spatial code From cell types to population dynamics: Making hippocampal manifolds physiologically interpretable 0:00 - Intro 5:29 - Hippocampus 9:31 - Sharp wave ripples 27:30 - Oscillations and epiphenomena 33:37 - Sharp wave ripples to manifolds 43:54 - Manifolds and single neuron types 49:45 - Hippocampus and granularity of cell types 59:23 - Explanation across levels 1:19:38 - Manifolds and higher cognition 1:29:46 - Brain Space and Time

The findings could influence how researchers interpret signals from techniques that use blood flow as a surrogate for neuronal activity.

Tessa Burg talks for a second time with Mariano Bosaz, Global VP of Consumer Data and Strategy at Coca-Cola and the author of “Digital Mindset.” This time, they dive deeper into practical applications of digital thinking, moving beyond theory to give you actionable strategies you can implement right away. Mariano shares real-world examples of how the shift from analog to digital thinking transforms problem-solving, particularly around the "last mile challenge" that affects so many industries. You'll discover what teams of the future look like and get concrete use cases from recent headlines that make these concepts accessible and immediately applicable.  Whether you're a business leader looking to stay ahead or someone curious about how AI-era marketing really works, this conversation offers valuable insights from someone operating at the highest levels of global business. Leader Generation is hosted by Tessa Burg and brought to you by Mod Op. Listen to the previous episode with Mariano here. About Mariano Bosaz: Mariano Bosaz is the author of Digital Mindset and an experienced digital leader serving as the Global VP of Data and Digital Head of China at The Coca-Cola Company. With a career spanning over two decades, his background includes founding and selling a digital business during his student exchange the University of Richmond in 1999 and holding key leadership roles such as Group Digital Director for Eurasia and Africa—overseeing 92 countries—and Vice President of Digital in Asia. In addition to his corporate experience, Mariano has served as an assistant professor at London Business School since 2015. His current work focuses on the intersection of emerging technologies and strategy, underpinned by research into blockchain and cryptocurrencies since 2020 and his role on the advisory boards of several AI startups. Mariano can be reached on LinkedIn or at marianobosaz.com.  About Tessa Burg: Tessa is the Chief Technology Officer at Mod Op and Host of the Leader Generation podcast. She has led both technology and marketing teams for 15+ years. Tessa initiated and now leads Mod Op's AI/ML Pilot Team, AI Council and Innovation Pipeline. She started her career in IT and development before following her love for data and strategy into digital marketing. Tessa has held roles on both the consulting and client sides of the business for domestic and international brands, including American Greetings, Amazon, Nestlé, Anlene, Moen and many more. Tessa can be reached on LinkedIn or at Tessa.Burg@ModOp.com.

In this Huberman Lab Essentials episode, I explain how salt (sodium) affects mental and physical performance, as well as cellular health. I describe how the brain monitors sodium levels to regulate thirst and fluid balance, and why salt needs can vary depending on activity level, stress, blood pressure, and diet. I also explain how to determine the right sodium intake for your individual needs and discuss why some people may benefit from increasing salt and other electrolytes. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman Function: https://functionhealth.com/huberman LMNT: https://drinklmnt.com/huberman Timestamps (00:00:00) Salt (00:00:37) Brain & Monitoring Salt (00:02:33) Thirst, Osmotic Thirst & Salt (00:05:35) Hypovolemic Thirst & Blood Pressure (00:06:59) Sponsor: Function (00:08:39) Fluid Balance, Kidney & Urine Regulation (00:11:53) How Much Salt Do You Need?, Blood Pressure, Dizziness & Postural Syndromes (00:17:29) Replenish Salt for Performance, Tool: Galpin Equation & Exercise (00:19:15) Sponsor: LMNT (00:20:46) Stress & Craving Salt (00:22:29) Electrolytes: Magnesium & Potassium; Low Carbohydrate Diet (00:25:19) Salt & Sweet Taste, Sugar Cravings, Processed Foods (00:29:37) Finding Your Ideal Salt Intake, Tool: Unprocessed Food Diet (00:31:25) Sponsor: AG1 (00:32:50) Neurons, Salt & Action Potentials; Ingesting Too Much Water (00:34:51) Recap & Key Takeaways Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices

We are delighted to host Benjamin Phelan on this episode of the ⁠mangu.tv⁠ podcast series. Benjamin Phelan is state-licensed in psychedelic-assisted therapy and has been in practice for the past twelve years, working with people from all walks of life. In addition to studies in psychology at Oberlin College, the University of Colorado and Naropa University, he has travelled extensively throughout Asia and South America studying non-Western approaches to mental health and spirituality. His approach combines transpersonal and depth psychology with Eastern and indigenous philosophies. He served as a writer for the documentary “Neurons to Nirvana: Understanding Psychedelic Medicines” and created the content for the AyaGuide personal development app.Benjamin speaks about his upbringing in Boulder, Colorado, at a time of the Beat poets, Nixon administration and the growing use of psychedelics for cultural change. He shares his first experience with psychedelics and speaks about how it opened up the language of non-human things. He talks about his rediscovery of psychedelics later in life, and how it led him to leave the corporate world and devote his life fully to the exploration of consciousness. Giancarlo and Ben discuss the ego and the soul. They talk about the value of therapy and guidance with psychedelics. Ben shares the importance of a daily practice to give a ‘leg up' to the richness of the interior world. He speaks about scientists' ability to measure enhanced brain states, found during meditation, prayer and altered states.

Over the last couple of years, most of my conversations around AI have been about capability. How fast models are improving. How agents are becoming more autonomous. How enterprises can adopt GenAI safely. How teams can redesign workflows around intelligence. But this week, I found myself thinking about something deeper. Not what AI can do. But what does AI cost? And I don't just mean money. I mean energy. I mean infrastructure. I mean the hidden assumptions underneath the current AI boom. Because when we talk about the future of AI, most people immediately jump to models, chips, data centers, agents, and software stacks. But as someone who works closely with organizations trying to operationalize AI in the real world, I keep coming back to a harder question: What happens when the current compute model itself becomes the bottleneck? This is not a question most teams are asking yet. But it is a question serious builders should start paying attention to. This week, while reviewing different enterprise AI patterns and thinking through long-term architecture choices, I realized that much of the current AI conversation still happens within the assumptions of silicon, scale, and software abstraction. But what if the next major shift is not a better model? What if it is a different computing substrate altogether? That's exactly why today's conversation is important. Because this episode is not about another AI app. It is not about another wrapper. It is not about another productivity layer. It is about something much more fundamental: What might come after silicon, and how should we think about it today? Chapters: 00:00 Introduction to Ewelina Kurtis and Final Spark 00:52 Understanding Living Neurons and Their Potential 02:44 The Vision Behind Final Spark 05:34 Current Progress and Future Goals 08:27 Collaborations and Research Opportunities 11:17 Programming Living Neurons 14:02 Ethical Considerations in Biocomputing 16:59 Benefits of Biocomputing for Society 19:39 Advice for Aspiring Bioengineers 22:30 Commercial Aspects of Final Spark 24:24 Investor Insights and Future Directions Episode # 184 Today's Guest: Dr. Ewelina Kurtys, Scientist from FinalSpark Website: FinalSpark What Listeners Will Learn: Why the future of AI may require rethinking computation itself, not just models How energy efficiency is becoming a core strategic issue in AI What biocomputing means in simple terms How living-neuron-based computing differs from traditional silicon-based systems Why future AI progress may depend on alternative hardware paradigms How emerging scientific computing trends should matter to enterprise AI leaders today Why staying ahead in AI means looking beyond current tools and architectures Resources: FinalSpark

Neurons play DOOM, ChatGPT adult mode, ranch dressing in Europe, Mario Day, UFC White House card

We're joined by Laura Tripaldi: material scientist, writer, and researcher at the Center for AI and Culture at NYU Shanghai. You probably know her from Parallel Minds: Discovering the Intelligence of Materials (Urbanomic, 2022), an essay in book form that became a phenomenon in theory and art circles. Tripaldi's work challenges one of the strongest contentions within the philosophy computation: that intelligence is substrate-indifferent, that it can scale and migrate independent of what carries it. She argues the opposite, that you cannot separate intelligence from the materials through which it is conveyed.This becomes experimentally clear in her recent essay Substrates Unbound (Antikythera, 2025), where she tracks biocomputing systems like DishBrain — living neuronal cultures interfaced with silicon chips that don't execute pre-given code but reorganize, learn, and adapt. Mouse neurons and human neurons perform differently under the same training conditions. This reframes a central question of the moment: not 'can we scale intelligence,' but which matter are we asking to think, under what energy regime, and at what cost?References:Tripaldi, Laura. Parallel Minds: Discovering the Intelligence of Materials (Urbanomic, 2022).Tripaldi, Laura. "Substrates Unbound" (Antikythera, 2025).Tripaldi, Laura. Soft Futures (newsletter, Substack).Haraway, Donna. A Cyborg Manifesto (1985).Parisi, Luciana. Abstract Sex: Philosophy, Biotechnology and the Mutations of Desire (Continuum, 2004) — source of the concept of hyper nature.Hui, Yuk. The Question Concerning Technology in China (Urbanomic, 2016) — source of the concept of cosmotechnics.Barad, Karen. Meeting the Universe Halfway: Quantum Physics and the Entanglement of Matter and Meaning (Duke, 2007) — onto-epistemology and intra-action.Irigaray, Luce — referenced as an influence on Tripaldi's feminist materialism.Pasquinelli, Matteo. The Eye of the Master: A Social History of Artificial Intelligence (Verso, 2023) — discussed in relation to technology as captured labor; Tripaldi pushes back via the history of automata.Laschi, Cecilia. Soft Robotics Lab, National University of Singapore — pioneer of octopus-inspired soft robotics.Hookway, Branden. Interface (MIT Press, 2014).

Headlines:  – Welcome To Mo News (02:00) – Ayatollah Killed As US & Israel Launch Massive Attack On Iran (06:45) – FBI Investigates Deadly Texas Bar Shooting For Possible Terrorism Ties (29:10) – Trump Admin Moves To Block Anthropic, Pentagon Pens Deal With OpenAI (30:30) – NASA Revises Plan To Return Americans To The Moon To Address Safety Concerns (34:10) – Super-Agers' Brains Generate 2x The Neurons, Study Suggests (36:00) – On This Day In History (40:00) Thanks To Our Sponsors:  –⁠ Industrious⁠ - Coworking office. 50% off day pass | Code: MONEWS50 – Surfshark - 4 additional months of Surfshark VPN | Code: MONEWS – Monarch - 50% off your first year | Code: MONEWS – Factor - 50% off your first box | Code: monews50off – ShipStation - Try for free for 60 days | Code: MONEWS – Shopify – $1 per-month trial | Code: MONEWS

What makes things last, and what do very different lasting things have in common? Why might a space alien not be able to understand music? Why do windows in medieval cathedrals look thicker at the bottom, and what does this reveal about the world’s religions? What was the most important weapon in ancient history, and how did it disappear? Join today for the story of persistence, from sharks to schizophrenia to Roman concrete to DNA.

Can the aging brain still make new neurons?   A landmark 2026 Nature study analyzed 355,997 human hippocampal nuclei using single-nucleus RNA sequencing and ATAC sequencing. Neurogenesis persists into adulthood—but chromatin accessibility collapses early in Alzheimer's disease.   SuperAgers showed a 2.5-fold increase in immature neurons and a preserved resilience signature.   Epigenetics may be the earliest battlefield in cognitive decline.

For decades, neuroscience treated the brain like a digital machine — storing information in synaptic connections and sustaining activity like a switch flipped on. But what if that model is incomplete?In this conversation, I sit down with Earl Miller, MIT professor and head of the Miller Lab, to explore a growing shift in cognitive neuroscience: the brain may compute using dynamic electrical waves.We discuss how oscillations coordinate millions of neurons, how waves interact with spikes in a two-way system, why large-scale brain organization may depend on rhythmic patterns, and what this means for artificial intelligence.If cognition isn't just stored in connections — but emerges from real-time analog wave computation — how should we rethink intelligence? TIMESTAMPS:(0:00) - Introduction: Mind-Brain Relationship Explained(0:27) - Brain as an Analog System: Dynamic Wave Computation(0:59) - 20th Century Brain Models: Connectionist Cognition(2:04) - AI Limitations from Old Brain Models(2:35) - Storing Information in Synaptic Connections(3:29) - Self-Organizing Brain & Internal Control Systems(4:29) - Brain Waves for Large-Scale Organization(5:17) - Spikes and Waves: Two-Way Brain Interaction(6:30) - Electrical Oscillations: Excitation & Inhibition Patterns(9:30) - Advantages of Wave-Based Processing over Logic Gates(11:00) - Coordinating Millions of Neurons for Attention(12:30) - Goals, Plans & Intentions Driving Brain Activity(15:30) - Real-Time Control: Synapses vs Waves Debate(18:30) - Generating New Brain Wave Patterns in Real Time(23:00) - Implications for AI & Cognitive Science(27:30) - Evolving Views on Cortical Computation & Oscillations(32:00) - High & Low Energy Phases in Brain Waves Explained(38:00) - Waves as a Mechanism for Self-Organization(44:00) - Real Analog Computation Through Wave Interactions(1:15:26) - Closing ThoughtsEPISODE LINKS:- Earl's Website: https://ekmillerlab.mit.edu/earl-miller/- Earl's Publications: https://scholar.google.com/citations?user=hv8jgk8AAAAJ&hl=en- Earl's X: https://x.com/MillerLabMIT- Earl's LinkedIn: https://www.linkedin.com/in/earlkmiller/- Cognition is an emergent property: https://doi.org/10.1016/j.cobeha.2024.101388- Analog Theory:https://loc.closertotruth.com/theory/millers-brain-waves-analog-organization-of-cortex- Cognition Emerges From Neural Dynamics Lecture: https://youtu.be/ie58Ujqy0vACONNECT:- Website: https://mindbodysolution.org - YouTube: https://youtube.com/@MindBodySolution- Podcast: https://creators.spotify.com/pod/show/mindbodysolution- Twitter: https://twitter.com/drtevinnaidu- Facebook: https://facebook.com/drtevinnaidu - Instagram: https://instagram.com/drtevinnaidu- LinkedIn: https://linkedin.com/in/drtevinnaidu- Website: https://tevinnaidu.com=============================Disclaimer: The information provided on this channel is for educational purposes only. The content is shared in the spirit of open discourse and does not constitute, nor does it substitute, professional or medical advice. We do not accept any liability for any loss or damage incurred from you acting or not acting as a result of listening/watching any of our contents. You acknowledge that you use the information provided at your own risk. Listeners/viewers are advised to conduct their own research and consult with their own experts in the respective fields.

Oxytocin has become known for having anti-anxiety and affiliative behavioral effects. That's why clinicians and researchers are excited about using oxytocin as a potential therapeutic. Brian Trainor is a professor at UC Davis, and his lab has been studying this complexity for the past decade. For an animal model, they work with a territorial, aggressive, monogamous rodent species called California mice. If the male is removed and the female is forced to defend their nest, she will experience what's known as social defeat, and she will exhibit what's called inhibited affiliative behavior, the type that can be affected by oxytocin — and this effect can be studied in a mouse's brain.Read the full study here: https://www.nature.com/articles/s41386-026-02352-y Hosted on Acast. See acast.com/privacy for more information.

You just have to be a good parent 30-40% of the time. According to the research, and parenting expert Maggie Dent.

If we’re all in the people business, then every leader needs to ask one question: What tools are in your toolbox? On this episode of Like It Matters Radio, Mr. Black unpacks the science and structure behind human behavior, motivation, and transformation. After nearly 34 years in the human potential field, he makes it clear: Nobody is broken. We are programmed. People run patterns—of thought, emotion, belief, and identity. And leaders who understand those patterns don’t just manage behavior… they transform it. This episode weaves together powerful frameworks including: Hebb’s Law – Neurons that fire together wire together Social Learning Theory – People model what they see Mimetic Theory – We imitate what we desire Attachment Theory – Secure relationships shape performance NLP patterning – Change the “how,” and the outcome changes You’ll also explore the deeper layers of transformation—Environment, Behavior, Capabilities, Beliefs, Identity, and Purpose—and why identity is the ultimate leadership superpower. If a pattern can be seen, it can be changed. If it can be changed, it can be repeated. If it can be repeated, it becomes a new reality. This episode equips leaders with practical insight to move, influence, and grow people from the inside out. Inspiration. Education. Application. When you live your life like it matters… it does. Be sure to Like and Follow us on our facebook page! www.facebook.com/limradio Instagram @likeitmattersradio Twitter @likeitmatters Get daily inspiration from our blog www.wayofwarrior.blog Learn about our non profit work at www.givelikeitmatters.com Check out our training website www.LikeItMatters.Net Always available online at www.likeitmattersradio.comSee omnystudio.com/listener for privacy information.

What actually happens when AI stops being a cloud-only experiment and starts running on desks, in labs, and inside real teams trying to ship real work? In this episode, I sit down with Logan Lawler, Senior Director at Dell Technologies, to unpack how AI workloads are really being built and supported on the ground today. Logan leads Dell's Precision and Pro Max AI Solutions business and hosts Dell's own Reshaping Workflows podcast, giving him a rare vantage point into how engineers, developers, creatives, and data teams are actually working, not how marketing slides suggest they should be. We start by cutting through the noise around AI PCs. At every conference stage, Logan breaks down what genuinely matters when choosing hardware for AI work. CPUs, GPUs, NPUs, memory, and software stacks all play different roles, and misunderstanding those roles often leads teams to overspend or underspec. Logan explains why all AI workstations qualify as AI PCs, but not all AI PCs are suitable for serious AI work, and why GPUs remain central for anyone doing real model development, fine-tuning, or inference at scale. From there, the conversation shifts to a broader architectural rethink. As AI workloads grow heavier and data sensitivity increases, many organizations are reconsidering where compute should live. Logan shares how GPU-powered Dell workstations, storage-rich environments, and hybrid cloud setups are giving teams more control over performance, cost, and data. We explore why local compute is becoming attractive again, how modern GPUs now rival small server setups, and why hybrid workflows, local for development and cloud for deployment, are becoming the default rather than the exception. One of the most compelling parts of the discussion comes when Logan connects hardware choices back to business reality. Drawing on real-world examples, he explains how teams use local AI environments to move faster, reduce cloud costs, and avoid getting locked into architectures that are hard to unwind later. This is not about abandoning the cloud, but about being intentional from the start, mainly as AI usage spreads beyond developers into marketing, operations, and everyday business roles. We also step back to reflect on a deeper challenge. As AI becomes easier to use, what happens to critical thinking, curiosity, and learning? Logan shares a candid perspective, shaped by his experiences as a parent, technologist, and podcast host, raising questions about how tools should support rather than replace thinking. If you are trying to make sense of AI PCs, local versus cloud compute, or how teams are really reshaping workflows with AI hardware today, this conversation offers grounded insight from someone living at the center of it. Are we designing systems that genuinely empower people to think better and build faster, or are we sleepwalking into decisions we will regret later? How do you want your own AI workflow to evolve? Useful Links TLDR AI newsletter and the Neurons. The Reshaping Workflows podcast Connect with Logan Lawler Follow Dell Technologies on LinkedIn

Human pluripotent stem cells (hPSCs) are transforming the study of biology and disease by enabling scientists to grow large amounts of specific cell types in the lab that were once difficult to obtain. Our guests today focus on improving the derivation and study of sensory neurons, which are sparse and diverse nerve cells near the spine that carry information like pain, touch, or position of the body to the brain. Damage to these neurons or sensory neuropathies, as can happen in diabetes or infections, is estimated to affect millions of people worldwide, yet treatments are limited. To improve the generation of human sensory neurons, the authors developed a genetic toolkit to fluorescently label these individual cells and their subtypes. This approach enables more precise study of these subtypes, their roles in disease, and potentially the development of treatments for sensory neuropathies. GuestsJoriene C. de Nooij, PhD, Department of Neurology, Columbia University, USA Eti Malka-Gibor, PhD, Department of Neurology, Columbia University, USA HostJanet Rossant, Editor-in-Chief, Stem Cell Reports and The Gairdner FoundationSupporting ContentPaper link: Derivation and analysis of human somatic sensory neuron subtypes facilitated through fluorescent hPSC reporters," Stem Cell ReportsAbout Stem Cell ReportsStem Cell Reports is the open access, peer-reviewed journal of the International Society for Stem Cell Research (ISSCR) for communicating basic discoveries in stem cell research, in addition to translational and clinical studies. Stem Cell Reports focuses on original research with conceptual or practical advances that are of broad interest to stem cell biologists and clinicians. X: @StemCellReportsAbout ISSCRAcross more than 80 countries, the International Society for Stem Cell Research (@ISSCR) is the preeminent global, cross-disciplinary, science-based organization dedicated to advancing stem cell research and its translation to medicine.ISSCR StaffKeith Alm, Chief Executive OfficerShuangshuang Du, Scientific Programs ManagerYvonne Fisher, Managing Editor, Stem Cell ReportsKym Kilbourne, Director of Media and Strategic CommunicationsMegan Koch, Senior Marketing ManagerJack Mosher, Scientific DirectorHunter Reed, Senior Marketing Coordinator 

Degradation-resistant proteins pass from neurons to glial cells in a process that may spread protein clumps around the brain, according to a study in mice.

The two lectures span human networks from neurons (Col 3) to nations (Mt 28) in discipleship…

The two lectures span human networks from neurons (Col 3) to nations (Mt 28) in discipleship…

In order to feel less stressed (and stop yelling), you've got to learn to understand and care for your nervous system. You'll Learn:The two parts of your nervous system and how they work togetherWhy managing your stress is so importantSignals that you're in a stress responseSome of my favorite mini stress resets (and where you can get a list of them for free)I'm zooming out to talk about the bigger picture of your entire central nervous system. And I'll show you how you can use your own nervous system to calm yourself more quickly.-------------------------------------------Your Nervous System ExplainedThere are two main parts of your nervous system. The first is your sympathetic nervous system. You might also have heard this talked about as your fight/flight/freeze/faint/fawn response). The second part is your parasympathetic nervous system, which includes the vagus nerve. The two parts work together to help you respond to stressful situations and then decrease that stress response, kinda like a teeter totter. One is activated at a time, while the other is decreased. Think of your nervous system as an information highway running through your body at all times. It takes in information through your senses and tells the brain how to respond to what you are experiencing. Neurons (brain cells) carry this message all throughout your body. If your brain interprets any of this information as dangerous, it triggers your stress response and activates the sympathetic nervous system. To your brain, a threat can be something like a kid spitting in your face or getting a bad grade or spilling juice all over the table. Stress juice floods your body, giving you the oomph to respond to the danger. When your stress response is activated, there is a period of time where you aren't able to regulate your nervous system. When that threat has passed, you start to come back online and your parasympathetic nervous system comes into play. The parasympathetic nervous system is your best friend when it comes to managing your stress response. It has its own network of nerves and helps relax your body after periods of stress or danger. It typically activates on its own after a stressor, but when we have triggers coming at us all the time (like in parenting life), it gets weakened and doesn't respond as well. That's why you need tools to reset the system on your own. When we talk about calm and taking pause breaks to reset, the parasympathetic nervous system is the piece that we're resetting. Chronic StressYour stress response is healthy and necessary. But often, our brains misinterpret things (like spilled juice being a life-or-death emergency). Parenting is a lot. What ends up happening is that you have a lot of demands and stressors coming at you one after the next, and you don't always have enough time to recover from them.This causes us to be chronically stressed. We constantly have stress juice pouring through our bodies, and it makes it really difficult to stay calm.This is what's going on when you find yourself getting angry and annoyed about every single thing your kid does. You've probably been in an activated stress response for a while, so you are dysregulated. As a mom, you're dealing with stressors all day long, especially if you have more than one kid. But there are little breaks in between.Our goal is to practice getting ourselves into the parasympathetic nervous system so that we can more easily recover from stress. We want that teeter totter to go easily up and down so that we flow smoothly between the two states of stress and non-stress. The way to do this is to...

Recorded by K. A. Hays for Poem-a-Day, a series produced by the Academy of American Poets. Published on January 29, 2026. ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠www.poets.org⁠

Support the show to get full episodes, full archive, and join the Discord community. The Transmitter is an online publication that aims to deliver useful information, insights and tools to build bridges across neuroscience and advance research. Visit thetransmitter.org to explore the latest neuroscience news and perspectives, written by journalists and scientists. Read more about our partnership. Sign up for Brain Inspired email alerts to be notified every time a new Brain Inspired episode is released. To explore more neuroscience news and perspectives, visit thetransmitter.org. Michael Shadlen is a professor of neuroscience in the Department of Neuroscience at Columbia University, where he's the principle investigator of the Shadlen Lab. If you study the neural basis of decision making, you already know Shadlen's extensive research, because you are constantly referring to it if you're not already in his lab doing the work. The name Shadlen adorns many many papers relating the behavior and neural activity during decision-making to mathematical models in the drift diffusion family of models. That's not the only work he is known for, As you may have gleaned from those little intro clips, Michael is with me today to discuss his account of what makes a thought conscious, in the hopes to inspire neuroscience research to eventually tackle the hard problem of consciousness - why and how we have subjective experience. But Mike's account isn't an account of just consciousness. It's an account of nonconscious thought and conscious thought, and how thoughts go from non-conscious to conscious His account is inspired by multiple sources and lines of reasoning. Partly, Shadlen refers to philosophical accounts of cognition by people like Marleau-Ponty and James Gibson, appreciating the embodied and ecological aspects of cognition. And much of his account derives from his own decades of research studying the neural basis of decision-making mostly using perceptual choice tasks where animals make eye movements to report their decisions. So we discuss some of that, including what we continue to learn about neurobiological, neurophysiological, and anatomical details of brains, and the possibility of AI consciousness, given Shadlen's account. Shadlen Lab. Twitter: @shadlen. Decision Making and Consciousness (Chapter in upcoming Principles of Neuroscience textbook). Talk: Decision Making as a Model of thought Read the transcript. 0:00 - Intro 7:05 - Overview of Mike's account 9:10 - Thought as interrogation 21:03 - Neurons and thoughts 27:05 - Why so many neurons? 36:21 - Evolution of Mike's thinking 39:48 - Marleau-Ponty, cognition, and meaning 44:54 - Naturalistic tasks 51:11 - Consciousness 58:01 - Martin Buber and relational consciousness 1:00:18 - Social and conscious phenomena correlated 1:04:17 - Function vs. nature of consciousness 1:06:05 - Did language evolve because of consciousness? 1:11:11 - Weak phenomenology and long-range feedback 1:22:02 - How does interrogation work in the brain? 1:26:18 - AI consciousness 1:35:49 - The hard problem of consciousness 1:39:34 - Meditation and flow

What if neurons aren't the foundation of mind? In this Mind-Body Solution Colloquia, Michael Levin and Robert Chis-Ciure challenge one of neuroscience's deepest assumptions: that cognition and intelligence are exclusive to brains and neurons.Drawing on cutting-edge work in bioelectricity, developmental biology, and philosophy of mind, this conversation explores how cells, tissues, and living systems exhibit goal-directed behavior, memory, and problem-solving — long before neurons ever appear.We explore: • Cognition without neurons• Bioelectric networks as control systems• Memory and learning beyond synapses• Morphogenesis as collective intelligence• Implications for AI, consciousness, and ethicsThis episode pushes neuroscience beyond the neuron, toward a deeper understanding of mind, life, and intelligence as continuous across scales.TIMESTAMPS:0:00 – Introduction: Why Neuroscience Must Go Beyond Neurons3:12 – The Central Claim: Cognition Is Not Exclusive to Brains7:05 – Defining Cognition, Intelligence, and Agency Without Neurons11:02 – Bioelectricity as a Control Layer for Morphogenesis15:08 – Cells as Problem-Solvers: Goals, Memory, and Error Correction19:41 – The Body as a Cognitive System: Scaling Intelligence Across Levels24:10 – Developmental Plasticity and Non-Neural Decision-Making28:36 – Morphological Computation and Collective Cellular Intelligence33:02 – Challenging Neuron-Centric Neuroscience Assumptions37:18 – Bioelectric Networks vs Neural Networks: Key Differences41:55 – Memory Without Synapses: Storing Information in Living Tissue46:07 – Rewriting Anatomy: Regeneration, Repatterning, and Control50:29 – Cancer, Developmental Errors, and Cognitive Breakdown54:48 – Pluribus: Philosophical Implications59:14 – From Cells to Selves: Where Does Agency Begin?1:03:22 – Implications for AI: Intelligence Without Brains or Neurons1:08:11 – Rethinking Consciousness: Gradualism vs Binary Models1:12:47 – Ethics of Expanding the Moral Circle Beyond Humans1:17:31 – Future Science: New Tools for a Post-Neuron Neuroscience1:22:54 – Closing Reflections: Life, Mind, and Intelligence All the Way DownEPISODE LINKS:- Cognition All the Way Down 2.0: Neuroscience Beyond Neurons in the Diverse Intelligence Era: https://link.springer.com/article/10.1007/s11229-025-05319-6- Robert's Publications: https://scholar.google.com/citations?user=7V9C7skAAAAJ&hl=en- Mike's Podcast 1: https://www.youtube.com/watch?v=v6gp-ORTBlU- Mike's Podcast 2: https://www.youtube.com/watch?v=kMxTS7eKkNM- Mike's Podcast 3: https://www.youtube.com/watch?v=1R-tdscgxu4- Mike's Podcast 4 (with Terrence Deacon): https://youtu.be/HuWbHwPZd60?si=z2unvX37OjXMjjIv- Mike's Lecture: https://www.youtube.com/watch?v=aQEX-twenkA- Mike's Channel: https://www.youtube.com/@drmichaellevin- Mike's Website: https://drmichaellevin.org/- Mike's Blog: https://thoughtforms.lifeCONNECT:- Website: https://mindbodysolution.org - YouTube: https://youtube.com/@mindbodysolution- Podcast: https://creators.spotify.com/pod/show/mindbodysolution- Twitter: https://twitter.com/drtevinnaidu- Facebook: https://facebook.com/drtevinnaidu - Instagram: https://instagram.com/drtevinnaidu- LinkedIn: https://linkedin.com/in/drtevinnaidu- Website: https://tevinnaidu.com=============================Disclaimer: The information provided on this channel is for educational purposes only. The content is shared in the spirit of open discourse and does not constitute, nor does it substitute, professional or medical advice. We do not accept any liability for any loss or damage incurred from you acting or not acting as a result of listening/watching any of our contents. You acknowledge that you use the information provided at your own risk. Listeners/viewers are advised to conduct their own research and consult with their own experts in the respective fields.

Stem cell science is reshaping treatment for complex disorders of the brain and spinal cord. Researchers develop cell based therapies to replace lost dopaminergic neurons in Parkinson's disease, fill gaps across spinal cord injuries, and calm seizure networks in refractory epilepsy by restoring the balance of inhibition and excitation. Teams test immune cell therapies against Epstein Barr virus infected B cells in multiple sclerosis and collaborate to move treatments across the blood brain barrier to reach diseased cells. Clinicians combine imaging in the operating room, surgical tools, and research on biological age and the pace of aging to understand disease and guide treatment. Patient advocates describe challenges and hopes for better options, and contemporary art reflects on perception in digital and physical worlds. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 40992]

Stem cell science is reshaping treatment for complex disorders of the brain and spinal cord. Researchers develop cell based therapies to replace lost dopaminergic neurons in Parkinson's disease, fill gaps across spinal cord injuries, and calm seizure networks in refractory epilepsy by restoring the balance of inhibition and excitation. Teams test immune cell therapies against Epstein Barr virus infected B cells in multiple sclerosis and collaborate to move treatments across the blood brain barrier to reach diseased cells. Clinicians combine imaging in the operating room, surgical tools, and research on biological age and the pace of aging to understand disease and guide treatment. Patient advocates describe challenges and hopes for better options, and contemporary art reflects on perception in digital and physical worlds. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 40992]

Stem cell science is reshaping treatment for complex disorders of the brain and spinal cord. Researchers develop cell based therapies to replace lost dopaminergic neurons in Parkinson's disease, fill gaps across spinal cord injuries, and calm seizure networks in refractory epilepsy by restoring the balance of inhibition and excitation. Teams test immune cell therapies against Epstein Barr virus infected B cells in multiple sclerosis and collaborate to move treatments across the blood brain barrier to reach diseased cells. Clinicians combine imaging in the operating room, surgical tools, and research on biological age and the pace of aging to understand disease and guide treatment. Patient advocates describe challenges and hopes for better options, and contemporary art reflects on perception in digital and physical worlds. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 40992]

Stem cell science is reshaping treatment for complex disorders of the brain and spinal cord. Researchers develop cell based therapies to replace lost dopaminergic neurons in Parkinson's disease, fill gaps across spinal cord injuries, and calm seizure networks in refractory epilepsy by restoring the balance of inhibition and excitation. Teams test immune cell therapies against Epstein Barr virus infected B cells in multiple sclerosis and collaborate to move treatments across the blood brain barrier to reach diseased cells. Clinicians combine imaging in the operating room, surgical tools, and research on biological age and the pace of aging to understand disease and guide treatment. Patient advocates describe challenges and hopes for better options, and contemporary art reflects on perception in digital and physical worlds. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 40992]

Stem cell science is reshaping treatment for complex disorders of the brain and spinal cord. Researchers develop cell based therapies to replace lost dopaminergic neurons in Parkinson's disease, fill gaps across spinal cord injuries, and calm seizure networks in refractory epilepsy by restoring the balance of inhibition and excitation. Teams test immune cell therapies against Epstein Barr virus infected B cells in multiple sclerosis and collaborate to move treatments across the blood brain barrier to reach diseased cells. Clinicians combine imaging in the operating room, surgical tools, and research on biological age and the pace of aging to understand disease and guide treatment. Patient advocates describe challenges and hopes for better options, and contemporary art reflects on perception in digital and physical worlds. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 40992]

The atlas also offers up molecular and cellular targets for new pain therapies.

This is the audio version of a White Board Series.Video https://youtu.be/ocE0__RrTjM?si=oYsu4v4vyunt9RMDInsula and Salience Network https://youtu.be/XpzXkN-5ghA?si=0_3RKXe3C9aRZgERAutism & Salience Network on 6 weeks old https://youtu.be/_JQdir0V6Cg?si=pwJUzwv4BaspWluXFull Episode Spindle Neurons, Salience Network, & Social Behaviors https://youtu.be/FlPMVHnls-4?si=NyGyzrAknwVwNSGSFull Episode Autism and Adaptive Responses, and exploring the mPFC, ACC, and Insula https://youtu.be/Zj3_e6ZjCGk?si=VhHRN9HG5tJGKfcEFull Episode Autism and the Salience Network https://youtu.be/9ZbTztb3al8?si=WVv1txx39Y42l09bVon Economo neurons (VEN), sometimes called Spindle Neurons, are the brain's rare, giant ‘social superhighway' cells that let us make split-second intuitive judgments in complex social environments — and in autism these cells are significantly abnormal- some increased amounts in key brain hubs, some morphological impairments like altered soma, dendrite, or cytoarchitecture (remember microtubules for this role, too). These abnormal developed VENs are pulling the salience network toward raw sensory input instead of flexible social cognition.Daylight Computer Company, use "autism" for $50 off at https://buy.daylightcomputer.com/autismChroma Light Devices, use "autism" for 10% discount at https://getchroma.co/?ref=autismFig Tree Christian Golf Apparel & Accessories, use "autism" for 10% discount at https://figtreegolf.com/?ref=autismCognity AI for Autistic Social Skills, use "autism" for 10% discount at https://thecognity.com00:00 Spindle Neurons Introduction, Discovery, Species03:40 Brain Regions, Rapid Transmission, Neuropeptide Y07:20 Anterior Cingulate Cortex (ACC) Roles, Adaptive Responses11:00 Insula Functions, Salience Network Hubs14:40 Salience Network Nodes, Infant fMRI Study (UCLA 2024)18:20 Spindle vs Pyramidal Neuron Shape, Layer 5B Location22:00 Spindle Neurons in Autism, Lack of Adaptive ResponsesX: https://x.com/rps47586YT: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuAemail: info.fromthespectrum@gmail.com

This episode dives deep into excitatory neurons—the brain's primary “go” signal—and their outsized role in the autistic phenotype. We explore how pyramidal neurons, powered by glutamate through AMPA and NMDA receptors, drive lightning-fast information transmission, synaptic hyperplasticity via BDNF, and elevated gamma oscillations (30–80 Hz) in V1, S1, and A1. This overactive excitatory push, paired with reduced parvalbumin and somatostatin inhibition, creates the well-documented E:I imbalance that fuels sensory hypersensitivity, one-trial learning, rigid memory encoding, repetitive behaviors, and the classic distal-connection timing mismatch from early sensory cortices to prefrontal regions.The autistic brain gets to the first two stops blazingly fast yet struggles to reach the final destination typical brains arrive at effortlessly.Inhibition Episodes: https://youtu.be/cjwbog7Rk4c?si=uSaLLNmS5EJLa_iHhttps://youtu.be/Oee4L7Vsj4E?si=Y5F2eVudCLhkxNw1 https://youtu.be/PBHVssvoQkM?si=A6SPedQi-Dt-DVO_E/I https://youtu.be/ETChjRQ0SzQ?si=yIFNovzldwSZRMeThttps://youtu.be/jl0xwjnyXII?si=dmk49CMQo3Uf17axDaylight Computer Company, use "autism" for $50 off at https://buy.daylightcomputer.com/autismChroma Light Devices, use "autism" for 10% discount at https://getchroma.co/?ref=autismFig Tree Christian Golf Apparel & Accessories, use "autism" for 10% discount at https://figtreegolf.com/?ref=autismCognity AI for Autistic Social Skills, use "autism" for 10% discount at https://thecognity.com00:00 Excitatory Neurons, Push-Pull System, Parvalbumin Deficiency03:30 E:I Imbalance, Sensory Hypersensitivity, Repetitive Behaviors07:00 Pyramidal Neurons, Glutamate, AMPA/NMDA Receptors10:30 Brain Regions: DLPFC, Anterior Insula, V1 S1 A114:00 Amygdala Misnomer, Low Road vs High Road, Emotional Hub18:30 Receptors: AMPA 1-5ms, NMDA 10-200ms, mGluR Modulatory22:00 Gamma Oscillations, BDNF Hyperplasticity, Sensory Overload25:30 Distal Connections, Point-A-to-Point-B Timing Mismatch29:00 BDNF Critical Period, One-Trial Learning, Rigid Memory32:30 TRN Dysfunction, Repetitive Behaviors, Corticostriatal Circuit34:30 Go-Signal vs Stop-Signal, Push-Pull Bowling Bumpers36:00 Rubenstein & Merzenich 2003, E:I Imbalance Foundation37:08 Daylight Computer Company, use "autism" for $50 discount39:32 Chroma Light Devices, use "autism" for 10% discount42:35 Reviews/Ratings & Contact InfoX: https://x.com/rps47586YT: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuAemail: info.fromthespectrum@gmail.com

My guest is Dr. Christof Koch, PhD, a pioneering researcher on the topic of consciousness, an investigator at the Allen Institute for Brain Science and the chief scientist at the Tiny Blue Dot Foundation. We discuss the neuroscience of consciousness—how it arises in our brain, how it shapes our identity and how we can modify and expand it. Dr. Koch explains how we all experience life through a unique “perception box,” which holds our beliefs, our memories and thus our biases about reality. We discuss how human consciousness is changed by meditation, non-sleep deep rest, psychedelics, dreams and virtual reality. We also discuss neuroplasticity (rewiring the brain), flow states and the ever-changing but also persistent aspect of the “collective consciousness” of humanity. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AGZ by AG1: https://drinkagz.com/huberman BetterHelp: https://betterhelp.com/huberman Our Place: https://fromourplace.com/huberman Helix: https://helixsleep.com/huberman LMNT: https://drinklmnt.com/huberman Timestamps (0:00) Christof Koch (2:31) Consciousness; Self, Flow States (8:02) NSDR, Yoga Nidra, Liminal States; State of Being, Intelligence vs Consciousness (13:14) Sponsors: BetterHelp & Our Place (15:53) Self, Derealization, Psychedelics; Selflessness & Flow States (19:53) Transformative Experience, VR, Racism & Self; Perception Box, Bayesian Model (28:29) Oliver Sacks, Empathy & Animals (34:01) Changing Outlook on Life, Tool: Belief & Agency (37:48) Sponsors: AGZ by AG1 & Helix Sleep (40:23) Alcoholics Anonymous (AA) & Higher Power (42:09) Neurobiology of Consciousness; Accidents, Covert Consciousness (51:09) Non-Responsive State; Disability Bias, Will to Live, Resilience (55:34) Will to Live, Akinetic Mutism, Neural Correlates of Consciousness (57:43) Conflicting Perception Boxes, Meta Prior, Religion, AI (1:06:47) AI, Violence, Swapping Perception Boxes, Video (1:12:19) 5-MeO-DMT, Psychedelics, Light, Consciousness & Awe; Loss of Self (1:20:54) Death, Mystical Experience, Ocean Analogy; Physicalism & Observer (1:27:57) Sponsor: LMNT (1:29:29) Meditation, Tool: Spacetime Bridging; Ball-bearing Analogy; Digital Twin (1:36:16) Mental Health Decline, Social Media, Pandemic, Family & Play, Tool: Body-Awareness Exercises (1:41:34) Dog Breeds; Movement, Cognitive Flexibility & Longevity (1:47:17) Cynicism, Ketamine, Tool: Belief Effect; Heroes & Finding Flaws (1:52:46) Cynicism vs Curiosity, Compassion; Deaths of Despair, Mental Health Crisis (1:57:26) Jennifer Aniston, Recognition & Neurons; Grandmother Hypothesis (2:03:20) Book Recommendation; Meaning of Life (2:09:10) Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, Sponsors, YouTube Feedback, Protocols Book, Social Media, Neural Network Newsletter Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices

In this Huberman Lab Essentials episode, I discuss science-supported nutrients that directly support brain structure, function and long-term cognitive health. I highlight specific nutrients, including omega-3 fatty acids, creatine, phosphatidylserine, anthocyanins, choline and glutamine, and discuss their recommended doses and dietary sources. I also describe how taste perception, gut-brain signaling and learned associations shape what foods we prefer and crave. Finally, I share practical behavioral tools to help rewire your food preferences toward healthier choices. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AGZ by AG1: https://drinkagz.com/huberman David: https://davidprotein.com/huberman LMNT: https://drinklmnt.com/huberman Timestamps 00:00:00 Food & Brain Health 00:01:32 Structural Fat & Neurons, Tools: Omega-3s, EPA; Phosphatidylserine 00:05:11 Acetylcholine & Focus, Tool: Dietary Choline 00:06:48 Creatine & Brain Health, Tool: Creatine Supplementation 00:08:26 Sponsor: David 00:09:41 Anthocyanins & Brain Function, Tool: Blueberries & Berries 00:10:52 Glutamine & Brain, Tool: Glutamine & Offset Sugar Cravings 00:12:48 Brain-Boosting Nutrients, Foods & Supplements 00:15:03 Food Preference; Yum, Yuck or Meh; Mouth, Taste & Palatability 00:19:30 Gut, Nutrients & Subconscious Signaling 00:21:56 Learned Food Preferences 00:23:36 Sponsors: AGZ by AG1 & LMNT 00:26:16 Food & Learned Associations, Tool: Unpair Artificial Sweeteners 00:30:18 Belief Effects, Satiety, Tool: Rewiring Food Preferences 00:35:48 Recap & Key Takeaways Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices

BASE64 Over DNS The base64 character set exceeds what is allowable in DNS. However, some implementations will work even with these invalid characters. https://isc.sans.edu/diary/BASE64%20Over%20DNS/32274 Google Chrome Update Google released an update for Google Chrome, addressing two vulnerabilities. One of the vulnerabilities is rated critical and may allow code execution. https://chromereleases.googleblog.com/2025/09/stable-channel-update-for-desktop_9.html Ivanti Updates Ivanti patched a number of vulnerabilities, several of them critical, across its product portfolio. https://forums.ivanti.com/s/article/September-Security-Advisory-Ivanti-Connect-Secure-Policy-Secure-ZTA-Gateways-and-Neurons-for-Secure-Access-Multiple-CVEs Sophos Patches Sophos resolved authentication bypass vulnerability in Sophos AP6 series wireless access point firmware (CVE-2025-10159) https://www.sophos.com/en-us/security-advisories/sophos-sa-20250909-ap6 Apple Introduces Memory Integrity Enforcement With the new hardware promoted in yesterday s event, Apple also introduced new memory integrity features based on this new hardware. https://security.apple.com/blog/memory-integrity-enforcement/

Neurons. Immune systems. MRIs. Weed gummies? One of the greats in neurology, Dr. Aaron Boster, takes time to chat all about Multiple Sclerosis, a neurological autoimmune disease close to our hearts. Alie's mom, your grammapod a.k.a. Fancy Nancy, was diagnosed with MS over two decades ago, and this episode explores in depth the factors that can cause MS, therapies that do – and don't –  show promise, how diet, exercise and mindfulness actually can help folks who have MS, the oftentimes agonizing journey to a diagnosis, and advice for those who've MS for a while – or are newly in the community. Also: yeah, weed. Visit the Boster Center for Multiple Sclerosis and follow Dr. Boster on YouTubeA donation went to MS Views and NewsMore episode sources and linksOther episodes you may enjoy: Disability Sociology (DISABILITY PRIDE), Diabetology (BLOOD SUGAR), Post-Viral Epidemiology (LONG COVID), Dolorology (PAIN), Salugenology (WHY HUMANS REQUIRE HOBBIES), Psychedeliology (HALLUCINOGENS), Cardiology (THE HEART), Somnology (SLEEP)400+ Ologies episodes sorted by topicSmologies (short, classroom-safe) episodesSponsors of OlogiesTranscripts and bleeped episodesBecome a patron of Ologies for as little as a buck a monthOlogiesMerch.com has hats, shirts, hoodies, totes!Follow Ologies on Instagram and BlueskyFollow Alie Ward on Instagram and TikTokEditing by Mercedes Maitland of Maitland Audio Productions and Jake ChaffeeManaging Director: Susan HaleScheduling Producer: Noel DilworthTranscripts by Aveline Malek Website by Kelly R. DwyerTheme song by Nick Thorburn

In this Huberman Lab Essentials episode, I explore the sensations of pain and pleasure, explaining how they are sensed in the body and interpreted by the brain as well as methods to control their intensity. I discuss both the hardwired mechanisms and subjective factors that shape an individual's perception of pain and pleasure. I also explain why pain thresholds vary from person to person and discuss various treatments for pain management such as acupuncture and supplements. Finally, I explain the role of key neurochemicals like dopamine and serotonin in mediating our experience of pain and pleasure. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman LMNT: https://drinklmnt.com/huberman Eight Sleep: https://eightsleep.com/huberman Timestamps 00:00:00 Pain & Pleasure 00:00:39 Skin, Appetitive vs Aversive Behaviors 00:02:10 Skin, Neurons & Brain 00:04:46 Brain Interpretation, Homunculus, Two-Point Discrimination Test 00:07:43 Pain & Pleasure, Subjective Interpretation 00:09:53 Sponsor: AG1 00:11:30 Tool: Pain & Expectation 00:13:08 Pain Threshold 00:14:46 Heat & Cold, Tool: Moving into Cold or Hot Environments 00:16:37 Subjective Pain, Psychosomatic, Fibromyalgia, Whole Body Pain, Acetyl-L-carnitine 00:20:54 Acupuncture, Electroacupuncture, Pain Management 00:23:44 Sponsors: LMNT & Eight Sleep 00:26:36 Red Heads & Pain Threshold, Endorphins 00:28:32 Improving Pain Threshold, Dopamine 00:30:00 Pleasure, Dopamine, Serotonin; Depression, Anti-depressants 00:34:12 Pleasure & Pain Balance, Dopamine, Addiction 00:36:08 Recap & Key Takeaways Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices