Podcasts about Plasticity

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Best podcasts about Plasticity

Latest podcast episodes about Plasticity

Science (Video)
Dissecting the Biological Complexity of Animal Regeneration

Science (Video)

Play Episode Listen Later Dec 3, 2025 57:01


Alejandro Sánchez Alvarado, Ph.D., argues that real progress in understanding regeneration comes from studying whole organisms rather than cells grown under artificial conditions. Sánchez Alvarado shows how observations from intact animals reveal organizing rules that narrow laboratory systems can miss. He presents evidence that stem cells in a studied animal lack detectable junctions with neighboring cells and instead respond to signals that travel across tissues. Sánchez Alvarado links this communication to extracellular vesicles that carry RNA and to metabolic support involving creatine, highlighting how distant tissues influence repair. Using imaging and molecular analyses, he tracks how signals move through the body and how specific cell populations change state during recovery. Sánchez Alvarado concludes that broad, comparative research is essential for uncovering general principles that govern how adult tissues restore form and function. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 40454]

Health and Medicine (Video)
Dissecting the Biological Complexity of Animal Regeneration

Health and Medicine (Video)

Play Episode Listen Later Dec 3, 2025 57:01


Alejandro Sánchez Alvarado, Ph.D., argues that real progress in understanding regeneration comes from studying whole organisms rather than cells grown under artificial conditions. Sánchez Alvarado shows how observations from intact animals reveal organizing rules that narrow laboratory systems can miss. He presents evidence that stem cells in a studied animal lack detectable junctions with neighboring cells and instead respond to signals that travel across tissues. Sánchez Alvarado links this communication to extracellular vesicles that carry RNA and to metabolic support involving creatine, highlighting how distant tissues influence repair. Using imaging and molecular analyses, he tracks how signals move through the body and how specific cell populations change state during recovery. Sánchez Alvarado concludes that broad, comparative research is essential for uncovering general principles that govern how adult tissues restore form and function. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 40454]

University of California Audio Podcasts (Audio)
Dissecting the Biological Complexity of Animal Regeneration

University of California Audio Podcasts (Audio)

Play Episode Listen Later Dec 3, 2025 57:01


Alejandro Sánchez Alvarado, Ph.D., argues that real progress in understanding regeneration comes from studying whole organisms rather than cells grown under artificial conditions. Sánchez Alvarado shows how observations from intact animals reveal organizing rules that narrow laboratory systems can miss. He presents evidence that stem cells in a studied animal lack detectable junctions with neighboring cells and instead respond to signals that travel across tissues. Sánchez Alvarado links this communication to extracellular vesicles that carry RNA and to metabolic support involving creatine, highlighting how distant tissues influence repair. Using imaging and molecular analyses, he tracks how signals move through the body and how specific cell populations change state during recovery. Sánchez Alvarado concludes that broad, comparative research is essential for uncovering general principles that govern how adult tissues restore form and function. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 40454]

Health and Medicine (Audio)
Dissecting the Biological Complexity of Animal Regeneration

Health and Medicine (Audio)

Play Episode Listen Later Dec 3, 2025 57:01


Alejandro Sánchez Alvarado, Ph.D., argues that real progress in understanding regeneration comes from studying whole organisms rather than cells grown under artificial conditions. Sánchez Alvarado shows how observations from intact animals reveal organizing rules that narrow laboratory systems can miss. He presents evidence that stem cells in a studied animal lack detectable junctions with neighboring cells and instead respond to signals that travel across tissues. Sánchez Alvarado links this communication to extracellular vesicles that carry RNA and to metabolic support involving creatine, highlighting how distant tissues influence repair. Using imaging and molecular analyses, he tracks how signals move through the body and how specific cell populations change state during recovery. Sánchez Alvarado concludes that broad, comparative research is essential for uncovering general principles that govern how adult tissues restore form and function. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 40454]

Science (Audio)
Dissecting the Biological Complexity of Animal Regeneration

Science (Audio)

Play Episode Listen Later Dec 3, 2025 57:01


Alejandro Sánchez Alvarado, Ph.D., argues that real progress in understanding regeneration comes from studying whole organisms rather than cells grown under artificial conditions. Sánchez Alvarado shows how observations from intact animals reveal organizing rules that narrow laboratory systems can miss. He presents evidence that stem cells in a studied animal lack detectable junctions with neighboring cells and instead respond to signals that travel across tissues. Sánchez Alvarado links this communication to extracellular vesicles that carry RNA and to metabolic support involving creatine, highlighting how distant tissues influence repair. Using imaging and molecular analyses, he tracks how signals move through the body and how specific cell populations change state during recovery. Sánchez Alvarado concludes that broad, comparative research is essential for uncovering general principles that govern how adult tissues restore form and function. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 40454]

UC San Diego (Audio)
Dissecting the Biological Complexity of Animal Regeneration

UC San Diego (Audio)

Play Episode Listen Later Dec 3, 2025 57:01


Alejandro Sánchez Alvarado, Ph.D., argues that real progress in understanding regeneration comes from studying whole organisms rather than cells grown under artificial conditions. Sánchez Alvarado shows how observations from intact animals reveal organizing rules that narrow laboratory systems can miss. He presents evidence that stem cells in a studied animal lack detectable junctions with neighboring cells and instead respond to signals that travel across tissues. Sánchez Alvarado links this communication to extracellular vesicles that carry RNA and to metabolic support involving creatine, highlighting how distant tissues influence repair. Using imaging and molecular analyses, he tracks how signals move through the body and how specific cell populations change state during recovery. Sánchez Alvarado concludes that broad, comparative research is essential for uncovering general principles that govern how adult tissues restore form and function. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 40454]

The Nature Recovery Podcast
Living in 'The What Ought to Be' with David Farrier

The Nature Recovery Podcast

Play Episode Listen Later Dec 3, 2025 36:11 Transcription Available


Send us a textProfessor David Farrier (University of Edinburgh) discusses his 2025 book Nature's Genius: Evolution's Lessons for a Changing Planet and explores how rapid, human-driven evolutionary pressures reveal both the fragility and inventive resilience of life. We cover urban evolution (birds and snails), domestication and self-domestication, collective and distributed forms of intelligence across living systems, and how rethinking time can help us reconnect with the natural world. The conversation balances urgency with hope: we can change behaviour and systems  - not by waiting for nature to “fix” things, but by learning from nature's adaptive strategies.Key takeaways:Human activities are now major selection pressures shaping evolution — sometimes rapidly.Plasticity (the ability of organisms to change gene expression and behaviour) offers insights for human adaptation — e.g., city design, economies, conservation strategies.Intelligence in nature is often collective and co-evolved; viewing ecosystems as forms of distributed intelligence could reshape politics and policy.Time matters: reframing our relationship with temporal scales (wild clocks vs. clock time) supports long-term thinking and reconnection.Nature recovery begins with “nature reconnection” — shifting how we see ourselves (embedded, not separate).Guest bio (brief): David Farrier is Professor of Literature and the Environment at the University of Edinburgh. His first book, Footprints: In Search of Future Fossils, examined the marks we are leaving on the planet and how they might appear in the deep-future fossil record; it was named a book of the year by both The Times and The Telegraph and has been translated into multiple languages. His new book Nature's Genius (2025) examines how life adapts under human-caused change and what lessons that offers for our own future and has been shortlisted for major awards.Buy the book / further reading: Nature's Genius: Evolution's Lessons for a Changing Planet — Canongate Books. Available as hardback, e-book and audio; shortlisted for the Wainwright Prize for Conservation Writing (and other 2025 recognitions). More details / purchase: https://canongate.co.uk/books/4911-natures-genius-evolution-039-s-lessons-for-a-changing-planet/ The Leverhulme Centre for Nature Recovery is interested in promoting a wide variety of views and opinions on nature recovery from researchers and practitioners. The views, opinions and positions expressed within this podcast are those of the speakers alone, they do not purport to reflect the opinions or views of the Leverhulme Centre for Nature Recovery, or its researchers.The work of the Leverhulme Centre for Nature Recovery is made possible thanks to the support of the Leverhulme Trust.

Wholistic Living
Episode 100: From Comfort Zone to Brain Zone: Unlocking Mental Flexibility

Wholistic Living

Play Episode Listen Later Nov 3, 2025 27:27


Discover how stepping outside your comfort zone can literally rewire your brain! In this episode of Wholistic Living, the science of neuroplasticity, showing how trying new things builds new synapses, strengthens neural networks, and boosts cognitive flexibility. Learn why novelty and challenge are essential for brain health, memory, and adaptability, and get practical tips to stimulate your brain every day, from learning new skills to simple daily habit changes. Backed by research on synaptic plasticity and brain growth, this episode is perfect for anyone looking to enhance mental performance, improve memory, and keep their mind sharp.I also share 4 NEW things that I have been doing the past couple months to challenge my brain!Join my FREE gut reset MASTERCLASS: https://mailchi.mp/holisticspring.com/reset-your-gut-workshopEquip Foods Grass-fed beef protein - Code: MARLAWant to work with me? email me to health@holisticspring.com

The Third Wave
From Placebo to Plasticity: What LSD Really Does – Conor Murray, Ph.D.

The Third Wave

Play Episode Listen Later Oct 27, 2025 50:45


In this episode of The Psychedelic Podcast, Paul F. Austin speaks with Dr. Conor H. Murray, a neuroscientist at UCLA whose research explores how psychedelics affect the brain. Find full show notes and links here: https://thethirdwave.co/podcast/episode-327/?ref=278  Conor shares insights from his placebo-controlled LSD microdosing study revealing measurable increases in neural complexity, suggesting unique neurological benefits even at sub-perceptual doses. He and Paul discuss what these findings mean for depression, addiction, and brain plasticity, as well as the future of citizen neuroscience through Conor's platform Psynautics. They also touch on his ongoing psilocybin study for cocaine use disorder and why low-dose research may hold keys to understanding consciousness itself. Interested in participating in Dr. Murray's Microdosing Study? Get 10% Off Your Enrollment! Use code WAVE3 to receive 10% off your study kit. https://www.psynautics.com/microdosing Conor Murray is a neuroscientist specializing in altered states of consciousness at UCLA. He is also the founder of Psynautics, the world's first citizen neuroscientist platform built for testing hypotheses related to altered states of mind and brain, from meditation to microdosing. His scientific expertise spans from the neurobiology of addiction to the effects of cannabis and psychedelics on the brain. Highlights How Dr. Murray entered psychedelic research by chance What LSD microdosing reveals about neural complexity The “sweet spot” around 13 micrograms for mental clarity Why placebo effects don't fully explain brain changes Microdosing vs macrodosing in neuroplastic outcomes BDNF, inflammation, and the mechanisms of healing Psilocybin's potential for cocaine use disorder How environment influences addiction and relapse The rise of citizen neuroscience and DIY EEG studies Where psychedelic science is headed next Episode Links Conor H. Murray, PhD Personal website Psynautics (Citizen Neuroscience Project) Psynautics Microdosing Study (Use code WAVE3 to receive 10% off your study kit) Episode Sponsors The Practitioner Certification Program by Third Wave's Psychedelic Coaching Institute. Golden Rule Mushrooms - Get a lifetime discount of 10% with code THIRDWAVE at checkout

The Human Risk Podcast
Dr Nikolay Kukushkin on Memory

The Human Risk Podcast

Play Episode Listen Later Oct 25, 2025 66:34


What if your body is learning things your mind doesn't know? What if memory wasn't just something that our brain has?Episode Summary On this episode, I'm exploring a bold idea with neuroscientist Dr Nikolay Kukushkin: memory doesn't just live in the brain. It might be a basic property of life itself. We unpack how scientists define memory (behavioural change over time) versus how the rest of us use the word, and why that distinction matters—from sea slugs to kidney cells. I ask the “muscle memory” question we all carry, and we separate the metaphor from the biology: your basal ganglia automate behaviours, but your muscle cells do literally adapt to patterned use.We go deep on “patterns.” Nikolay's work shows that even non-neural cells can detect minute-scale timing differences—preferring spaced pulses over a single crammed dose. That has huge implications for learning, exercise, nutrition, and even medicine; it suggests timing might be as important as quantity. We also talk about sleep as essential “synaptic housekeeping,” why false memories are an adaptive feature (not a failure), and what it really means to “run out of memory” in our overstimulated world.Finally, we tilt at the big questions: how consciousness might have evolved, why Plato's model of perception eerily echoes today's top-down/bottom-up neuroscience, and what AI still lacks—learning patterns in time within an embodied world. If you've ever crammed for an exam, worried about forgetting your own name, or wondered what your cells are quietly learning from your daily routines, this one will rewire how you think about memory.Guest Biography — Dr Nikolay KukushkinDr Nikolay Kukushkin is a Clinical Associate Professor at NYU. His book One Hand Clapping: Unraveling the Mystery of the Human Mind  traces how consciousness emerged from the natural world; the original Russian edition won the Enlightener (Prosvetitel) Award and the Alexander Belyaev Medal.His recent research (Nature Communications, Nov 2024) showed that non-neural human cells display the classic “spacing effect,” suggesting memory-like temporal patterning beyond the brain.AI-Generated Timestamped Summary [00:00:00] Cold open: reframing memory as cellular, not just neural. [00:01:00] Scientists' definition of memory vs everyday usage. [00:03:00] From behaviour change to cellular change; beyond “plugging a muscle into a brain.” [00:05:00] All cells have experiences; “pattern matters.” [00:06:00] Muscle memory: basal ganglia automation vs literal muscle adaptation. [00:07:00] Shared molecular machinery: “use it or lose it” in brain and muscle. [00:08:00] Nikolay's path: from molecules to minds; bottom-up neuroscience. [00:09:00] Protein quality control: molecular barcodes and cellular “conversations.” [00:11:00] Why sea slugs: short path from molecules to behaviour. [00:13:00] Hypothesis leap: if single neurons learn from pulses, could kidney cells? [00:14:00] The experiment: four 3-min pulses vs one 12-min pulse (spacing wins). [00:16:00] What's uniquely neural: synapses and specific connectivity; where salience arises. [00:19:00] Memory without awareness; non-neural systems can store patterns. [00:20:00] Applications: exercise, diet, medicine; timing as a lever. [00:23:00] The dark mirror: life as obsessive optimisation if we over-pattern. [00:24:00] Personal practice: being mindful of inputs, attention as filter. [00:26:00] Debunking “10% of the brain” and the sleep–memory link. [00:28:00] Sleep weakens synapses; deprivation leads to saturation and hallucinations. [00:30:00] The social-media “soup” analogy for saturated memory. [00:32:00] Names, identity and rehearsal; de-naming as degradation. [00:33:00] Reconsolidation: why false memories are a feature we need. [00:34:00] 9/11/Challenger studies: how memories drift with time. [00:36:00] Ebbinghaus and the spacing effect across species and systems. [00:39:00] Cramming vs spacing: initial strength and decay rates. [00:41:00] The forgetting curve and why “more” can decay slower in memory. [00:42:00] “My whole life is one big experiment on my brain.” [00:43:00] Practical “tip”: fix attention first; follow interest, not force. [00:45:00] Attention economy and selective inputs as memory hygiene. [00:48:00] From smoking to scrolling: a future of information hygiene. [00:50:00] One Hand Clapping: why it feels special to be you. [00:54:00] Plato's “two fires”: ancient echoes of top-down/bottom-up perception. [00:58:00] Intuition as hidden associations; LLMs as an analogy. [01:00:00] AI: excitement, unease, and the risk of outsourcing humanness. [01:03:00] What AI lacks: learning patterns in time without a body. [01:05:00] Close and thanks. [01:06:00] Outro and calls to action.LinksNikolay's website - https://www.nikolaykukushkin.com/His NYC profile - https://liberalstudies.nyu.edu/about/faculty-listing/nikolay-kukushkin.htmlHis book 'One Hand Clapping' - https://www.nikolaykukushkin.com/press-1'Memory Takes Time': research into how wemory is not confined to a particular location or locations in the brain - https://www.cell.com/neuron/fulltext/S0896-62731730467-1Herman Ebbinghaus - https://en.wikipedia.org/wiki/Hermann_Ebbinghaus and The Ebbinghaus Illusion: https://en.wikipedia.org/wiki/Ebbinghaus_illusion

Colloques du Collège de France - Collège de France
Colloque de rentrée 2025 - Une histoire de l'intelligence est-elle possible ? - Sur l'évolution technique de l'intelligence : une histoire artificielle

Colloques du Collège de France - Collège de France

Play Episode Listen Later Oct 16, 2025 36:08


Collège de FranceAnnée 2025-2026Colloque de rentrée 2025 - Une histoire de l'intelligence est-elle possible ? - Sur l'évolution technique de l'intelligence : une histoire artificielleDavid BatesProfessor, University of California, BerkeleyRésuméCet article retrace une histoire artificielle de l'intelligence naturelle, affirmant que, depuis l'émergence de la pensée moderne lors de la révolution scientifique en Europe, l'esprit et ses capacités ont été appréhendés comme intriqués dans les corps, les machines et les technologies prothétiques de la pensée, comme l'écriture. L'intelligence humaine a donc été appréhendée en termes d'automatisme. Compte tenu de l'hypertechnologisation contemporaine de la vie humaine, marquée par une automatisation croissante grâce aux infrastructures numériques, l'automatisation constitue une menace pour l'indépendance humaine tout en exigeant des décisions politiques et sociales d'une importance cruciale. Cette histoire artificielle tente de renouer avec une tradition de pensée de l'intelligence comme résistance à l'automatisme. Autrement dit, malgré la relation intime, voire constitutive, de l'esprit avec la technologie, celui-ci peut néanmoins abriter les moyens de ce que Bernard Stiegler appelle la désautomatisation, et ainsi réhabiliter la capacité humaine de décision. Partant de Descartes et du concept d'automate à l'époque moderne, cet article s'inscrit dans une réflexion qui intègre les conceptions de l'esprit, du cerveau et des machines aux XIXe et XXe siècles, les premiers dispositifs informatiques, la cybernétique et les théories d'après-guerre de l'interaction homme-machine, afin de suivre une certaine interaction entre l'esprit humain et l'ouverture au sein des formes techniques et machiniques de détermination. Nous conclurons par une critique de l'intelligence artificielle, affirmant que l'intelligence naît de la confrontation de l'esprit à l'automatisme, et non des processus automatiques en soi.David W. Bates is Professor in the Department of Rhetoric at the University of California, Berkeley, an affiliate with the Center for Science, Technology, Medicine and Society, and past Director of the Berkeley Center for New Media. He received his PhD in European History from the University of Chicago. His research and teaching is focused on the relations between technology and cognition, and the history of political and legal thought. His book An Artificial History of Natural Intelligence: Thinking with Machines from Descartes to the Digital Age will be published by the University of Chicago Press in Spring 2024. He has previously published two books on early modern thought — Enlightenment Aberrations: Error and Revolution in France (Cornell, 2002) and States of War: Enlightenment Origins of the Political (Columbia, 2011) — and edited (with Nima Bassiri) a volume Plasticity and Pathology: On the Formation of the Neural Subject (Fordham, 2015). Other publications include articles on topics such as Cybernetics, Artificial Intelligence, and 20th-century political and legal theory.

Spectrum Autism Research
New questions around motor neurons and plasticity

Spectrum Autism Research

Play Episode Listen Later Oct 10, 2025 10:37


A researcher's theory hangs muscle degeneration on a broken neural circuit.

RX'D RADIO
E610: Technique Isn't Enough: How Motor Learning Drives Real Adaptation

RX'D RADIO

Play Episode Listen Later Aug 20, 2025 55:45


Shallow and Jiunta break down the difference between technique, skill, and motor learning. From rehab to high-level performance, we explore how intention, quality of execution, and adaptability define your ability to actually get stronger, build muscle, and stay injury-free. Join the PSL1 Waitlist Now For Our Only Course Discount. https://www.pre-script.com/psl1 FREE Coach's Field Guide: https://www.pre-script.com/coachs-field-guide We've got a new sponsor! Marek Health is a health optimization company that offers advanced blood testing, health coaching, and expert medical oversight. Our services can help you enhance your lifestyle, nutrition, and supplementation to medical treatment and care. https://marekhealth.com/rxd Code RXD Don't miss the release of our newest educational community - The Pre-Script ® Collective! Join the community today at www.pre-script.com. For other strength training, health, and injury prevention resources, check out our website, YouTube channel, and Instagram. For more episodes, subscribe and tune in to our podcast. Also, make sure to sign up to our mailing list at www.pre-script.com to get the first updates on new programming releases. You can also follow Dr. Jordan Shallow and Dr. Jordan Jiunta on Instagram! Dr. Jordan Shallow: https://www.instagram.com/the_muscle_doc/ Dr. Jordan Jiunta: https://www.instagram.com/redwiteandjordan/ Early Podcast Struggles (00:00:00) Airplanes, Neck Pillows, and Public Weirdness (00:03:00) From Travel Devices to Gym Devices (00:06:40) Engineers Who Forget Physics at the Gym (00:07:50) Motor Learning vs. Technique (00:08:20) Intention, Adaptation, and Misaligned Training (00:10:10) Running Like You're Chased vs. Running with Skill (00:13:10) Motor Learning Always Comes First (00:15:30) Novices, Frequency, and False Progress (00:20:00) Redefining Success in Training Sessions (00:31:00) Rehab, Subjectivity, and Skill Isolation (00:34:20) Whole-Part-Whole Teaching Model (00:38:00) Showing Your Work: Coaching as Problem-Solving (00:41:00) Age, Plasticity, and Motor Learning Challenges (00:43:30) Coaching Youth vs. Older Athletes (00:47:30) Assessments, Movement Quality, and Coaching Experience (00:50:00) Subjective vs. Objective Progression (00:54:30)

Huberman Lab
How to Rewire Your Brain & Learn Faster | Dr. Michael Kilgard

Huberman Lab

Play Episode Listen Later Aug 11, 2025 189:50


In this episode, my guest is Dr. Michael Kilgard, PhD, a professor of neuroscience at the University of Texas at Dallas and a leading expert on neuroplasticity and learning across the lifespan. We discuss the need for alertness, effortful focus, post-learning reflection and sleep to induce neuroplasticity, and how dopamine, acetylcholine, serotonin and norepinephrine are each involved. He explains the behavioral steps for neuroplasticity, as well as vagal nerve stimulation (VNS) and other therapies for tinnitus, stroke, depression, PTSD and paralysis. This episode ought to be of use to anyone interested in understanding the modern science of brain rewiring and learning to improve cognitive or motor skills or treat sensory or motor disorders. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman Eight Sleep: https://eightsleep.com/huberman Wealthfront*: https://wealthfront.com/huberman Carbon: https://joincarbon.com/huberman Function: https://functionhealth.com/huberman *This experience may not be representative of the experience of other clients of Wealthfront, and there is no guarantee that all clients will have similar experiences. Cash Account is offered by Wealthfront Brokerage LLC, Member FINRA/SIPC. The Annual Percentage Yield (“APY”) on cash deposits as of December 27,‬ 2024, is representative, subject to change, and requires no minimum. Funds in the Cash Account are swept to partner banks where they earn the variable‭ APY. Promo terms and FDIC coverage conditions apply. Same-day withdrawal or instant payment transfers may be limited by destination institutions, daily transaction caps, and by participating entities such as Wells Fargo, the RTP® Network, and FedNow® Service. New Cash Account deposits are subject to a 2-4 day holding period before becoming available for transfer. Timestamps (00:00) Michael Kilgard (03:24) Neuroplasticity (05:13) Child vs Adult Plasticity, Childhood Development & Learning (09:37) Sponsors: Eight Sleep & Wealthfront (12:41) Kids, Real vs Artificial Experiences & Balance, Video Games, Natural World (21:13) Social Media & Videos, Kids, Overstimulation & Development (33:42) Early Language Development, Passive vs Real Experiences, Kids & Adults (39:23) Sponsors: AG1 & Carbon (42:44) Learning & Plasticity Requirements; Focus, Friction, Rest & Reflection (52:24) Brain Connections, Complexity, Life Experiences & Plasticity (1:02:51) Learning, Reflection, Visualization, Testing (1:09:45) Experience Diversity & Time, Happiness, Life Appreciation (1:18:05) Sponsor: Function (1:19:53) Learning & Life Meaning (1:23:25) Neuromodulators, Brain Complexity, Synaptic Eligibility Trace & Learning (1:34:28) Synapses, Therapy for PTSD, Rewiring the Brain (1:39:01) Vagus Nerve Stimulation (VNS), Stroke, Spinal Cord Injury, Tinnitus, PTSD (1:47:33) Psychedelics, Neurostimulation, Importance of Timing (1:57:47) Electroconvulsive Therapy (ECT) & Major Depression (2:01:51) Psychedelics/SSRIs as Plasticity Tools, SSRIs & Bone Strength, Failed Clinical Trials (2:13:18) Can VNS Accelerate Learning? (2:16:01) VNS Surgery, Patient Use & Specificity, Closed-Loop Vagus Nerve Stimulation (2:18:18) Tinnitus Cause, Incidence & Self-Amplification; PTSD & Control (2:28:12) VNS for Tinnitus; Disease Complexity & Treatments, Lazy Eye (2:41:05) Complexity of Disease Treatments & Combination Therapies (2:48:50) Brain-Machine Interfaces, Information & Experiences; Closed-Loop Feedback; Resilience (2:59:09) Evolving Clinical Trials, Combination Treatments & Disease Complexity (3:05:21) Acknowledgements (3:07:04) Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, Sponsors, YouTube Feedback, Protocols Book, Social Media, Neural Network Newsletter Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices

Disintegrator
34. Spirit (w/ Catherine Malabou)

Disintegrator

Play Episode Listen Later Aug 8, 2025 46:09


We couldn't be more honored to have Catherine Malabou on the pod, a serious inspiration for all of us. This episode covers so much, moving from AI to education to anarchism to feminism, but all grounded within a focus on automony -- the autonomy of language from us, the autonomy of an anarchic subject or an anarchic collective, the autonomy of the clitoris from gender, the autonomy of the plastic being or form with respect to change.If you're unfamiliar with Malabou's work, this is actually a really great place to start. Her work includes all of the above topics, and it pushes further into language, neuroscience, and politics than most philosophers dare. We've been following her since the epic What Should We Do With Our Brains?, the legendary Plasticity at the Dusk of Writing (whose fleshing out of Malabou's reading of the plastic inspired so many theorists, arists, and researchers across endless fields and disciplines), and our personal favorite, the recent Stop Thief! Anarchism and Philosophy. We'd almost recommend working backwards from this episode (as an Anglophone, I'm thinking in terms of English translation), going into Stop Thief and Pleasure Erased: The Clitoris Unthought before taking on the works on Hegel, Derrida, and plasticity.We're so so inspired by the freshness of Catherine Malabou's perspective on AI -- as always, she dares to say and formalize things that many philosophers treat reflexively. We hope to have more conversations on the topic of AI and education soon, following from Malabou's hot takes. :) 

Theoretical Neuroscience Podcast
On co-dependent excitatory and inhibitory plasticity - with Tim Vogels - #30

Theoretical Neuroscience Podcast

Play Episode Listen Later Jul 19, 2025 90:54


Synaptic plasticity underlies several key brain functions including learning, information filtering and homeostatic regulation of overall neural activity. While several mathematical rules have been developed for plasticity both at excitatory and inhibitory synapses, it has been difficult to make such rules co-exist in network models.  Recently the group of the guest has explored how co-dependent plasticity rules can remedy the situation and, for example, assure that long-term memories can be stored in excitatory synapses while inhibitory synapses assure long-term stability.

Equine Assisted World with Rupert Isaacson
Your Brain, Your Way: Curiosity, Neurodiversity, and Healing with Dr. Chantel Prat | EP 28 Equine Assisted World

Equine Assisted World with Rupert Isaacson

Play Episode Listen Later May 15, 2025 99:14 Transcription Available


In this episode of Equine Assisted World, Rupert Isaacson sits down with Dr. Chantel Prat—a neuroscientist, psychologist, linguist, and horsewoman. Dr. Prat teaches at the University of Washington and is the author of The Neuroscience of You, a groundbreaking book that examines how every brain is different and what that means for our lives, relationships, and learning processes.Rupert and Chantel dive deep into individual brain differences, the neuroscience of curiosity, attention, and empathy, and how equine-assisted practices can benefit from this knowledge. From mirror neurons to movement, nature, and neurodivergence, this episode explores how understanding our brains can transform education, therapy, leadership, and horsemanship.

Scientific Sense ®
Prof. Michael Frank of Brown Univ. on Brain, Memory, decision-making, uncertainty, and plasticity

Scientific Sense ®

Play Episode Listen Later May 3, 2025 55:07


Scientific Sense ® by Gill Eapen: Prof. Michael Frank is Professor of Cognitive and Psychological Sciences at Brown University. His research interests include Cognitive Neuroscience, Higher-Level Cognition, Neural/Computational Models of Mind Brain and Behavior.Please subscribe to this channel:https://www.youtube.com/c/ScientificSense?sub_confirmation=1

Stanford Medcast
Episode 102: Pediatric Pulse Mini-Series: Inside the Epileptic Brain - How Myelin Plasticity Could Change Epilepsy Care

Stanford Medcast

Play Episode Listen Later Apr 8, 2025 25:26 Transcription Available


Pediatric epilepsy is a complex condition that affects countless children, but advancements in treatment are paving the way for brighter futures. Join us as Dr. Juliet Knowles, Assistant Professor of Neurology at Stanford University, sheds light on the multifaceted nature of epilepsy in children. In this enlightening discussion, we'll explore the critical differences between seizures and epilepsy, the profound impact of early intervention on neonatal brain development, and the exciting advancements in genetics that promise to transform treatment options. Read Transcript CME Information: https://stanford.cloud-cme.com/medcastepisode102 Claim CE: https://stanford.cloud-cme.com/Form.aspx?FormID=3286

Ask the Naked Scientists Podcast
Is my microwave disrupting my Wi-Fi?

Ask the Naked Scientists Podcast

Play Episode Listen Later Apr 4, 2025 20:46


In this episode of Ask the Naked Scientist: does miso ferment differently in space? How can I improve my memory? Could receiving hepatitis A, tetanus, and typhoid vaccinations, in combination, cause chronic fatigue? Why does food go bad, and are food packet instructions accurate? What is brain plasticity, and how do we train it? What is mindfulness? Is my diabetes causing a strange smell in my urine? Like this podcast? Please help us by supporting the Naked Scientists

Ask the Naked Scientists
Is my microwave disrupting my Wi-Fi?

Ask the Naked Scientists

Play Episode Listen Later Apr 4, 2025 20:46


In this episode of Ask the Naked Scientist: does miso ferment differently in space? How can I improve my memory? Could receiving hepatitis A, tetanus, and typhoid vaccinations, in combination, cause chronic fatigue? Why does food go bad, and are food packet instructions accurate? What is brain plasticity, and how do we train it? What is mindfulness? Is my diabetes causing a strange smell in my urine? Like this podcast? Please help us by supporting the Naked Scientists

BizNews Radio
AI can be powerful stimulant for brain health and plasticity - George Vradenburg

BizNews Radio

Play Episode Listen Later Apr 4, 2025 14:23


Brain health has emerged as one of the defining challenges of our time, driven by a double whammy of soaring rates of neurological conditions such as stroke, dementia, and Parkinson's disease linked to ageing populations, alongside a rise in mental health issues among young people. To confront this escalating crisis, an initiative called Brain House was launched earlier this year at Davos, Switzerland. The initiative seeks to drive a unified global effort, bringing together stakeholders—from mental health experts to philanthropic and for-profit investors—to prioritise brain health like never before. Leading this movement is George Vradenburg, chairman and co-founder of the Davos Alzheimer's Collaborative (DAC). Vradenburg told Biznews in an interview that it is crucial to reduce risk factors, build brain resilience, and harness technology and AI to transform brain health outcomes. He emphasised that new technologies, such as AI, have consistently been adapted to extend the capabilities of our brains. “These technologies are powerful stimulants to brain plasticity and to brain health,” he remarked. A Health for Africa programme is set to launch at the G20 summit in South Africa this November.

Hypnosis and relaxation |Sound therapy
Promote the plasticity of brain nerves Release healing energy from the source Practice mindfulness in daily life Keep your body and mind healthy anytime, anywhere Clearly feel the sound effect of the sound flying over your head

Hypnosis and relaxation |Sound therapy

Play Episode Listen Later Mar 28, 2025 9:51


Support this podcast at — https://redcircle.com/hypnosis-and-relaxation-sound-therapy9715/donationsAdvertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

Mind & Matter
Gut Microbiome Plasticity | Peter Turnbaugh | 214

Mind & Matter

Play Episode Listen Later Mar 14, 2025 41:19


Send us a textShort Summary: How diet shapes the gut microbiome and impacts health, with microbiologist Dr. Peter Turnbaugh breaking down the complex science.About the guest: Peter Turnbaugh, PhD is a professor of microbiology and immunology at the University of California, San Francisco, where he leads a lab studying the gut microbiome's role in nutrition and drug response.Note: Podcast episodes are fully available to paid subscribers on the M&M Substack and everyone on YouTube. Partial versions are available elsewhere. Full transcript and other information on Substack.Episode Summary: Nick talks to Peter Turnbaugh discuss the pitfalls of oversimplified diet labels in research, Turnbaugh's studies comparing plant-based and animal-based diets in humans, and how these shifts rapidly alter gut microbes and short-chain fatty acid profiles. Key Takeaways:The term “high-fat diet” in research is often misleading, as it can include high carbs and vary widely, complicating study comparisons.In a 2014 study, switching humans to a plant-based (high-fiber) or animal-based (ketogenic, no-fiber) diet changed their gut microbiome within one day, showing its remarkable adaptability.Ketogenic diets reduce Bifidobacterium in the gut, which may lower inflammation-linked immune cells (Th17), potentially aiding conditions like multiple sclerosis.Short-chain fatty acids (e.g., butyrate) don't just come from fiber; they persist even on zero-fiber ketogenic diets, hinting at alternative microbial pathways.Gut microbes can activate or deactivate drugs, like antibiotics or digoxin, suggesting microbiomes may explain why drugs work differently across individuals.Ketone bodies like BHB alone can mimic some ketogenic diet effects on the microbiome and immunity, simplifying research and hinting at therapeutic potential.Related episode:M&M #203: Metagenomics, Microbiome Transmission, Gut Microbiome in Health & Disease | Nicola Segata*Not medical advice.Support the showAll episodes, show notes, transcripts, etc. at the M&M Substack Affiliates: Lumen device to optimize your metabolism for weight loss or athletic performance. Use code MIND for 10% off. Readwise: Organize and share what you read. Athletic Greens: Comprehensive & convenient daily nutrition. Free 1-year supply of vitamin D with purchase. KetoCitra—Ketone body BHB + potassium, calcium & magnesium, formulated with kidney health in mind. Use code MIND20 for 20% off any subscription. MASA Chips—delicious tortilla chips made from organic corn and grass-fed beef tallow. No seed oils or artificial ingredients. Use code MIND for 20% off. For all the ways you can support my efforts

Mind-Body Solution with Dr Tevin Naidu
Daniel McShea: What is Field Theory? Unseen Fields Guide All Goal-Directed Things in the Universe

Mind-Body Solution with Dr Tevin Naidu

Play Episode Listen Later Mar 6, 2025 66:54


Daniel McShea is Professor of Biology, and Associate Professor of Philosophy at Duke University. He is a scientist, philosopher and author. His work focuses on 2 main areas: 1) Evolution of Complexity: In a 2010 book with Robert Brandon, Biology's First Law, he argues that the complexity of organisms will tend to increase spontaneously in the absence of natural selection and other forces. In evolution, complexity is easy (and simplicity is hard.) A second book, The Missing Two Thirds of Evolutionary Theory (Brandon and McShea 2020), further develops the theory, offering a quantitative formulation.2) Teleology (purpose, goal directedness): A common physical structure underlies all goal-directed systems, from acorns turning into oak trees to homing torpedoes to human passions and purposes. All of these are hierarchically structured, consisting a small thing nested within a large thing, more precisely, a goal-directed entity moving within a larger directing field.TIMESTAMPS:(0:00) - Introduction (1:00) - What is Field Theory?(6:44) - Goal-Directedness(10:13) - Support for Field Theory(15:15) - Persistence & Plasticity(22:20) - Purposiveness & Teleology(31:10) - Free Will & Consciousness(41:15) - Internal Conflicts(44:30) - Future of Field Theory(53:40) - Intentionality(55:45) - External Influences vs Internal Fields(1:01:20) - Purpose in the Universe/Meaning of Life(1:05:20) - Final Thoughts(1:06:20) - ConclusionEPISODE LINKS:- Dan's Website: https://scholars.duke.edu/person/dmcshea- Dan's Work: http://www.biology.duke.edu/mcshealab/- Dan's Publications: https://scholar.google.com/citations?user=IB5lqFwAAAAJ&hl=en- Dan's Books: https://www.amazon.com/Books-Daniel-W-McShea/s?rh=n%3A283155%2Cp_27%3ADaniel%2BW.%2BMcShea- Elusive But Everywhere: https://aeon.co/essays/a-new-field-theory-reveals-the-hidden-forces-that-guide-us- Levin, Solms, Babcock, McShea: https://youtu.be/VUszs0nALxM?feature=shared- Levin, Babcock, McShea: https://youtu.be/7ZahEQGwc1g?feature=sharedCONNECT:- Website: https://tevinnaidu.com - Podcast: https://creators.spotify.com/pod/show/mindbodysolution- YouTube: https://youtube.com/mindbodysolution- Twitter: https://twitter.com/drtevinnaidu- Facebook: https://facebook.com/drtevinnaidu - Instagram: https://instagram.com/drtevinnaidu- LinkedIn: https://linkedin.com/in/drtevinnaidu=============================Disclaimer: The information provided on this channel is for educational purposes only. The content is shared in the spirit of open discourse and does not constitute, nor does it substitute, professional or medical advice. We do not accept any liability for any loss or damage incurred from you acting or not acting as a result of listening/watching any of our contents. You acknowledge that you use the information provided at your own risk. Listeners/viewers are advised to conduct their own research and consult with their own experts in the respective fields.

IngenioUs
IngenioUs Mini. Reimagining Higher Education: The Plasticity of Universities

IngenioUs

Play Episode Listen Later Feb 27, 2025 5:19


In his latest University Designs column and conversation, David Staley discusses the concept of plasticity in universities, drawing parallels with neuroplasticity in the human brain. He explores the challenges of institutional transformation and the importance of mindset shifts, as articulated in Jessica Riddell's work on hope circuits. The discussion emphasizes the need for universities to adapt and evolve, questioning their capacity for change and the role of language in shaping institutional practices.Key takeaways:Innovation in universities requires expansive thinking.Translating visionary ideas into tangible change is challenging.Hope is intertwined with learning and flourishing.Language influences our capacity to achieve change.Riddell presents a mindset shift for fostering change.We can rewire institutions for human flourishing.Institutional self-knowledge is critical for transformation.The neuroplasticity metaphor raises questions about institutional capacity for change.Are universities capable of the plasticity Riddell envisions?How plastic is our organization?Sounds bites:"We can rewire institutions for human flourishing.""Hope is a key mechanism in the rewiring process.""How plastic is our organization?"Chapters00:00The Plasticity of the University02:46Hope Circuits and Institutional Transformation04:12Challenges of Change in Higher Education

Boston Public Radio Podcast
BPR Full Show 02/21: Mental Plasticity

Boston Public Radio Podcast

Play Episode Listen Later Feb 21, 2025 150:53


GBH Music is about to kick off a new string of live jazz shows. For this week's Live Music Friday, we'll hear from four-time Grammy winner Oscar Stagnaro and his band TRIAD. We'll also talk about the series with GBH Music's Sam Brewer & JazzBoston's Ken Field.Retired Federal Judge Nancy Gertner on what courts can and can't do to reign in Trump's orders on birthright citizenship and the mass firing of federal officials. Love Letters advice columnist Meredith Goldstein on why our brains lose plasticity as we age and how this impacts our relationships.We launch a new media analysis segment with GBH's Callie Crossley & Adam Reilly.

Love Letters
The Gates of Plasticity

Love Letters

Play Episode Listen Later Feb 11, 2025 31:38


Meredith sits down with Dr. Steven Hyman – a brain expert at The Broad Institute – for a talk about the meaning of change … and whether it's actually possible. Are people capable of change – in life and relationships? If so, how? Dr. Hyman explains the plastic brain, how it works, how eating a great sandwich in Chicago can be the best thing ever, and why Meredith once thought she looked like Reese Witherspoon. We also catch up with a very special Love Letters couple. Learn more about your ad choices. Visit megaphone.fm/adchoices

Defenders Podcast
Defenders: Excursus on Creation of Life and Biological Diversity (Part 19): The Plasticity and Flexibility of ANE Myths

Defenders Podcast

Play Episode Listen Later Jan 29, 2025


Defenders: Excursus on Creation of Life and Biological Diversity (Part 19): The Plasticity and Flexibility of ANE Myths

The EMJ Podcast: Insights For Healthcare Professionals
Hema Now: Episode 7: Decoding T Cells and Advancing Immunology

The EMJ Podcast: Insights For Healthcare Professionals

Play Episode Listen Later Jan 2, 2025 41:43


This week, Jonathan is joined by Dr Shahram Kordasti, Associate Professor in Applied Cancer Immunopathology at King's College London, UK. In this episode, Dr Kordasti discusses the immunobiology of Myelodysplastic syndrome and Aplastic anaemia, the role of CD4+ T cells in myeloid malignancies, and how cutting-edge computational tools are enhancing treatment strategies.   Timestamps:  (00:00)-Introduction  (01:23)-Hodgkin's lymphoma origin   (04:21)- Immunobiology of diseases  (08:55)-Plasticity of T cells   (13:42)-Computational biology and multiomics for patient stratification  (21:00)-Standardising immune monitoring  (25:41)- Pretreatment with systemic agents  (27:55)- Myeloproliferative neoplasms  (31:48)-Synthetic data generation   (36:22)-Exciting developments on the horizon   (39:16)-Three wishes for healthcare  

Health and Medicine (Video)
A Tale of Two Barriers: Plasticity of Lung Epithelium and Mesothelium

Health and Medicine (Video)

Play Episode Listen Later Dec 18, 2024 58:40


Le Xu, Ph.D., examines the intricate processes underlying lung development and disease, with a focus on idiopathic pulmonary fibrosis (IPF). Xu explores the roles of genetic and cellular mechanisms, including the hedgehog pathway, FGF signaling, and epithelial-mesenchymal interactions, in driving lung fibrosis. Xu also highlights links between congenital diaphragmatic hernia (CDH) and lung development, suggesting that both mechanical and genetic factors contribute to lung hypoplasia. The discussion includes the development of advanced mouse models that replicate key aspects of human IPF, offering insights into fibrosis progression. Xu's research ultimately seeks to identify the causes of lung tissue abnormalities and pave the way for targeted therapies. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 39460]

University of California Audio Podcasts (Audio)
A Tale of Two Barriers: Plasticity of Lung Epithelium and Mesothelium

University of California Audio Podcasts (Audio)

Play Episode Listen Later Dec 18, 2024 58:40


Le Xu, Ph.D., examines the intricate processes underlying lung development and disease, with a focus on idiopathic pulmonary fibrosis (IPF). Xu explores the roles of genetic and cellular mechanisms, including the hedgehog pathway, FGF signaling, and epithelial-mesenchymal interactions, in driving lung fibrosis. Xu also highlights links between congenital diaphragmatic hernia (CDH) and lung development, suggesting that both mechanical and genetic factors contribute to lung hypoplasia. The discussion includes the development of advanced mouse models that replicate key aspects of human IPF, offering insights into fibrosis progression. Xu's research ultimately seeks to identify the causes of lung tissue abnormalities and pave the way for targeted therapies. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 39460]

Health and Medicine (Audio)
A Tale of Two Barriers: Plasticity of Lung Epithelium and Mesothelium

Health and Medicine (Audio)

Play Episode Listen Later Dec 18, 2024 58:40


Le Xu, Ph.D., examines the intricate processes underlying lung development and disease, with a focus on idiopathic pulmonary fibrosis (IPF). Xu explores the roles of genetic and cellular mechanisms, including the hedgehog pathway, FGF signaling, and epithelial-mesenchymal interactions, in driving lung fibrosis. Xu also highlights links between congenital diaphragmatic hernia (CDH) and lung development, suggesting that both mechanical and genetic factors contribute to lung hypoplasia. The discussion includes the development of advanced mouse models that replicate key aspects of human IPF, offering insights into fibrosis progression. Xu's research ultimately seeks to identify the causes of lung tissue abnormalities and pave the way for targeted therapies. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 39460]

The Trip Report
Special Dispatch: Regulatory Plasticity with Matt Zorn

The Trip Report

Play Episode Listen Later Nov 19, 2024 60:57


Welcome to another Special Dispatch from The Trip Report Podcast, a production of Beckley Waves. Today, I am speaking with Matt Zorn, a litigator and partner at Yetter Coleman. With a practice spanning antitrust, competition, IP, and a deep focus on controlled substances and drug regulation, Matt brings a unique perspective to the shifting landscape of drug policy and health agency reform.What makes this discussion especially relevant today is the backdrop of the recent political realignment in the U.S., with RFK Jr.'s role within a Trump administration and the Make America Healthy Again (MAHA) initiative looming over the political landscape.As a result, we find ourselves at a unique inflection point to reassess drug policy and, perhaps, a pivotal moment of mental health, psychedelics, and regulatory processes.Matt's insights don't shy away from the complex history and challenges facing the psychedelic movement and broader healthcare reform. He argues that the FDA's structure itself may not be fit for purpose in modern mental health treatment.In our conversation, we explore:* The origins and inefficiencies of current drug regulation processes.* Why the Controlled Substances Act and FDA efficacy requirements may hinder real-world applications.* How reforming clinical trial processes or even fundamentally changing statutory requirements could reshape the space.* Concrete ideas for reforming the system, including lessons drawn from MDMA's recent regulatory struggles.* How drug development pathways intertwine with controlled substances law, patent incentives, and the broader economic landscape of pharmaceuticals.Without further ado, I bring you my conversation with Matt Zorn.Listen to the episode on Substack, Spotify, Google or Apple.Credits:* Hosted by Zach Haigney * Produced by Zach Haigney, Erin Greenhouse, and Katelin Jabbari* Find us at thetripreport.com* Follow us on Instagram, Twitter, LinkedIn and YouTubeTheme music by MANCHO Sounds, Mixed and Mastered by Rollin Weary This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit www.thetripreport.com

Huberman Lab
Bill Eddy: How to Deal With High Conflict People

Huberman Lab

Play Episode Listen Later Oct 28, 2024 159:21


In this episode, my guest is Bill Eddy, a lawyer, licensed therapist, professional mediator, and faculty member at the Pepperdine University School of Law. He specializes in identifying, reducing friction with, and disentangling from high-conflict individuals. We explain how high-conflict personalities differ from personality disorders and examine the cycles of blame and drama that cause persistent conflict in their relationships. We discuss how to quickly recognize high-conflict individuals based on specific criteria and behaviors, helping listeners learn to spot their less obvious tactics. You'll also learn how to disengage from them with minimal friction and understand the methods they use to draw people back in or keep conflict alive. Additionally, we cover effective communication strategies for mediating situations involving high-conflict individuals, emphasizing empathy and problem-solving approaches. This episode equips listeners with tools to navigate conflict in various contexts, promoting resolutions that benefit all parties involved. Access the full show notes for this episode at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman Maui Nui Venison: https://mauinuivenison.com/huberman ExpressVPN: https://expressvpn.com/huberman Function: https://functionhealth.com/huberman David Protein: https://davidprotein.com/huberman Timestamps 00:00:00 Bill Eddy 00:02:58 Sponsors: Maui Nui & ExpressVPN 00:06:41 High-Conflict Families, High-Conflict Individuals & Patterns 00:10:48 Personality Disorders, Prevalence & Overlap 00:18:28 High-Conflict Personality vs. Personality Disorders, Blame 00:24:33 High-Conflict Individuals, Tool: First-Year Rule & Commitment 00:30:53 Sponsor: AG1 00:32:05 Relationship Stability, Tool: Vetting Potential Partners 00:38:54 Heightened Emotions, Negative Advocates, Divorce 00:47:50 Brain, Plasticity & Fear; Bullies, Polarization 00:54:51 Sponsors: Function & David 00:58:00 Emotions, Media, Politics 01:04:57 Tool: WEB Method, Identify High-Conflict Individuals 01:12:20 Body Cues, Identify High-Conflict Individuals 01:18:40 Tool: Don't Label & Empathy; Adapting Your Behavior 01:23:12 High Conflict Personalities & Occupations 01:28:18 Big Personalities: Evidence vs Assumptions 01:37:27 Tool: Leaving a Combative High-Conflict Individual, Blame, Gradual Exit 01:45:41 Exiting a High Conflict Relationship & Timing 01:49:27 Tool: Disentangling from a Victim High-Conflict Individual, “Hoovering” 01:52:32 High Conflict Divorce, Small Families & Parental Estrangement 01:57:01 Tool: Managing Emotions & Relationships, EAR Statements 01:59:52 Large Families & Conflict Resolution 02:04:11 Bullies & Online Social Groups 02:09:18 Personality Disorders, Causes, Culture 02:13:09 Tool: 4 “Fuhgeddaboudits”, Topics to Avoid in High Conflict Resolution 02:19:50 Tool: CARS Method, Connecting & EAR Statements, Analyzing 02:27:03 Tool: CARS Method, Responding & BIFF Response, Setting Limits & SLIC 02:36:40 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, Sponsors, YouTube Feedback, Protocols Book, Social Media, Neural Network Newsletter Disclaimer & Disclosures

The Trip Report
#34 Shamil Chandaria: Computational Neuroscience and Human Flourishing

The Trip Report

Play Episode Listen Later Oct 17, 2024 107:22


Welcome back to The Trip Report Podcast, a production of Beckley Waves.Today's conversation is with Shamil Chandaria, and as I alluded to in last week's newsletter introducing computational neuroscience—it is the longest and most technical conversation we've had to date.I have wanted to speak with Shamil since I watched his lecture at Oxford titled The Bayesian Brain and Meditation.Shamil is a former advisor to Google DeepMind, co-foudner and research fellow at Imperial College London Centre for Psychedelic Research and Oxford University's Centre for Eudaimonia and Human Flourishing, and a co-author with Robin Carhart-Harris and the Imperial team of the influential 2023 paper titled Canalization and Plasticity in Psychopathology, Importantly for this conversation, Shamil is also a longtime meditation practitioner, and his current work is dedicated to exploring contemplative practices, spiritual awakening, and psychedelics through the lens of computational neuroscience. At the heart of the conversation is the Free Energy Principle, a relatively new concept in cognitive neuroscience that conceives of the brain as a prediction machine constantly updating its internal models to minimize prediction errors. This framework along with the Bayesian Brain Hypothesis show how the brain optimally processes sensory data through inference, which has profound implications for how we perceive and experience the world.We discuss:* The brain as a prediction machine* The convergence of ancient wisdom and modern neuroscience.* Defining human flourishing beyond the absence of suffering to include meaning, love, joy, connection, and psychological resilience.* The role of body sensations, emotions, and somatic practices in psychotherapy and how they tie into the brain's predictive coding mechanisms.* Spiritual awakening, liberation and human flourishing through a neurocomputational lens* The potential for integrating free energy principle-based models into the field of psychiatry, improving therapeutic approaches and mental health care.* And much moreMy takeaway from this conversation is that we are, in fact, in the midst of a paradigm shift—one that bridges the fields of meditation, psychology, psychedelics, phenomenology, psychiatry, and even artificial intelligence. This new understanding, grounded in the free energy principle, offers a unified theory that links ancient wisdom with modern neuroscience, reshaping how we think about consciousness, well-being, and what it means to be sentient.And now, I bring you my conversation with Shamil Chandaria.I want to highlight our friends at the Tiny Blue Dot Foundation (TBD), who have just announced their latest Request for Proposals for scientific studies of the Perception Box.Tiny Blue Dot Foundation strives to help people understand that they live in their own unique Perception Box whose walls can be expanded to minimize suffering, increase acceptance of self and others, and view trauma and other challenges as opportunities for growth.TBD has allocated $9,000,000 to fund up to 10 rigorous research projects related to The Science of the Perception Box. TBD ran similar RFPs over the last two years and funded a total of 23 projects thus far. Information about these projects can be found here and here.Listen to the episode on Substack, Spotify, Google or Apple.Credits:* Hosted by Zach Haigney * Produced by Zach Haigney, Erin Greenhouse, and Katelin Jabbari* Find us at thetripreport.com* Follow us on Instagram, Twitter, LinkedIn and YouTubeTheme music by MANCHO Sounds, Mixed and Mastered by Rollin Weary This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit www.thetripreport.com

Talklaunch with Ryan Estes
Denver Walls, Vintage Markets, Woof-O-Ween, and Our Favorite Denver Coffee Shops!

Talklaunch with Ryan Estes

Play Episode Listen Later Oct 1, 2024 45:59


October 1st,  2024 - It's getting chilly. Warm up at our must see coffee spots around town and hear what's going on this week!   As always, we're sharing our favorite upcoming cultural events, art openings, concerts, and all of the things that make Denver the city we're proud to call home.   Follow WDG: YouTube: https://www.youtube.com/channel/UC8u8GmvBi6th6LOOMCuwJKw Instagram: https://www.instagram.com/whats_good_denver/ TikTok: https://www.tiktok.com/@whatsgooddenver   Do you have a Denver event, cause, opening, or recommendation that you want to share with us? We want to hear from you! Tell us what's good at tom@kitcaster.com.     The Goods:   FIRST FRIDAY!!   Colorado Rapids vs LA Galaxy @ Dicks Sporting Goods Park   Red Rocks Schedule   Denver Walls 2024 @ RiNo Art District   Genomic Approaches to Understanding Adaptation and Plasticity at High Altitude @ CU Museum of Natural History   Whisky Library Tasting @ Spirit Hound Denver Tasting Room   Idaho Springs Literary Festival @ Idaho Springs   Old School Cool First Friday Vintage Market @ The Bird Lot   Pet Pawrade and Woof-O-Ween @ Aspen Grove     Coffee Shop Feature:   Metropolis Coffee   Improper City   The Welton Room (espresso martinis)   Stellas   The Molecule Effect       Our Sponsor: Kitcaster Podcast Agency Music produced by Troy Higgins  

Science & Spirituality
263 | How Your Attention Shapes Reality: A Quantum Approach To Form New Neural Pathways In Your Brain & Improve Your Life

Science & Spirituality

Play Episode Listen Later Sep 2, 2024 45:58


Have you ever wondered why what you focus on seems to expand in your life? We're breaking down the science behind this phenomenon, exploring how the power of your attention isn't just a mental exercise—it's a force that literally creates new neural pathways in your brain. We even touch on the mind-bending double slit experiment in quantum physics, which shows that the mere act of observation can change the behavior of particles. Imagine what that means for your day-to-day reality! But it doesn't stop there. We discuss how your attention, when combined with imagination, can be a potent tool for creating the life you truly desire. In a world where our attention spans are shrinking, learning how to sustain your focus on your goals is more important than ever. So, what are you paying attention to? Is it helping you grow, or is it holding you back? Tune in to discover how you can harness the power of your attention to rewire your brain, achieve your goals, and transform your life. Plus, don't miss the chance to book a free strategy session with us to explore your goals and get personalized guidance! Ready to receive support on your growth journey? Book a free 1 hour Strategy Session with Kevin! In this 1:1 zoom call, you'll get clear on the main challenges you're facing, solidify your vision of a dream life, and discover practical steps to take to bridge the gap from where you are to where you want to be. This session is valued at $250, but today it's Kevin's gift to you. Only 15 sessions are available this month, so schedule your call now: https://scienceandspirituality.mykajabi.com/calendar Double slit experiment Youtube Video - https://www.youtube.com/watch?v=Q1YqgPAtzho Chapters 00:00 Introduction to the Power of Attention 03:21 The Power of Attention and Energy Flow 05:17 Compound Effect and the Importance of Small Actions 08:01 Social Media and the Grasp for Attention 13:07 The Double Slit Experiment and the Influence of Consciousness 19:21 Perception and the Plasticity of Circumstances 24:11 The Power of Attention: Consciously Creating Your Reality 26:08 Accountability and Support: Enhancing Focus and Achieving Goals 39:14 Limiting Negativity: A More Effective Approach

Ironweeds
239 - Mental Plasticity

Ironweeds

Play Episode Listen Later Aug 26, 2024 70:55


There's plastic in our brains. The DNC is led by a terrifying joyful warrior. Cops in Iowa shoot a family dog in front of a child. Tourism is going haywire around the world. Charging for plastic bags may be having a positive effect on UK beaches.    https://e360.yale.edu/digest/microplastics-human-brains   https://www.thenation.com/article/politics/aoc-dnc-speech-gaza/   https://www.motherjones.com/politics/2024/08/dnc-speech-uncommitted-movement-harris-walz-ruwan-romman/   https://www.ourquadcities.com/news/local-news/watch-davenport-officer-fatally-shoots-dog-family-wants-answers/   https://www.thenation.com/article/politics/dnc-gaza-genocide/   https://www.cnn.com/travel/tourism-why-it-went-wrong?cid=ios_app   https://www.theguardian.com/environment/article/2024/jul/29/number-of-plastic-bags-found-on-uk-beaches-down-80-since-charge-introduced   https://apnews.com/article/abortion-new-york-election-2024-ad674ee66389e3703a847fa385a308c7

Mind & Matter
Epigenetics, Chromatin Plasticity & the Neural Basis of Memory | Giulia Santoni | #169

Mind & Matter

Play Episode Listen Later Aug 9, 2024 83:45 Transcription Available


Send us a Text Message.About the guest: Giulia Santoni, PhD is a neuroscientist who obtained her PhD at the EPFL in Switzerland, where she studied epigenetic influences on memory formation.Episode summary: Nick and Dr. Santoni discuss: transcription & gene regulation; synaptic plasticity; learning & associative memory; epigenetics, histones, DNA methylation, and mechanisms of gene regulation; chromatin plasticity & the neural basis of memory formation; and more.Related episodes:Emotion, Cognition, Consciousness, Behavior & Brain Evolution | Joseph LeDoux | #73Cognitive Neuroscience, Cognitive Flexibility & Control, Attention, Working Memory, Multitasking & Behavior | Tobias Egner | #130*This content is never meant to serve as medical advice.Support the Show.All episodes (audio & video), show notes, transcripts, and more at the M&M Substack Try Athletic Greens: Comprehensive & convenient daily nutrition. Free 1-year supply of vitamin D with purchase.Try SiPhox Health—Affordable, at-home bloodwork w/ a comprehensive set of key health marker. Use code TRIKOMES for a 10% discount.Try the Lumen device to optimize your metabolism for weight loss or athletic performance. Use code MIND for 10% off.Learn all the ways you can support my efforts

The Wellness Process
Healing From Rare Cancer at 27: The Power Of Mindset, Emotional Plasticity, Alternative Treatments, Diet & Building A Non-Toxic Home With Rachel Yaffe

The Wellness Process

Play Episode Listen Later Jul 16, 2024 45:43


For additional, weekly tea-filled episodes, join the TWP PatreonFollow us on Instagram: www.instagram.com/wellnessprocesspodFollow us on TikTok: https://www.tiktok.com/@thewellnessprocessProduced by Peoples Media Hosted on Acast. See acast.com/privacy for more information.

Huberman Lab
Perform with Dr. Andy Galpin: Why Muscle Matters & How to Build It

Huberman Lab

Play Episode Listen Later Jun 19, 2024 116:27


I'm honored to share Episode 2 of the first season of Perform with Dr. Andy Galpin. Dr. Andy Galpin is a tenured full professor at California State University, Fullerton, where he co-directs the Center for Sport Performance and leads the Biochemistry and Molecular Exercise Physiology Laboratory. Andy is both a friend and a colleague, and I'm delighted to have assisted in the creation of this podcast. I'm certain you'll both enjoy and learn from it. Season 1 features 10 episodes, airing every Wednesday for 10 weeks. Dr. Galpin will cover everything from building strength, the importance of strength for long-term health, the science of breathing, the benefits of sleep extension, genetic testing for personalized training, and nutrition for injury recovery. While we have Episode 2 of Perform with Dr. Andy Galpin here, please be sure to subscribe and follow Perform with Dr. Andy Galpin on your preferred platform. Show notes for this episode can be found at performpodcast.com. Timestamps 00:00:00 Introduction from Dr. Andrew Huberman 00:01:06 Skeletal Muscle 00:04:06 Sponsors: Absolute Rest & Momentous 00:07:20 Quantity & Quality; Organ System; Health & Performance 00:12:58 Plasticity, “Look Good, Feel Good, Play Good”; Muscle Types 00:15:46 What is Muscle?, Muscle Fibers, Tendon 00:21:37 Muscle Fiber Number, Hyperplasia, Anabolic Steroids, Age 00:24:03 Myonuclei & Adaptability 00:26:27 Muscle Fiber Types, Variable Muscle Functions 00:32:24 Fiber Type & Lifestyle Factors 00:34:54 Sponsors: David Protein & AG1 00:37:37 Age & Muscle Loss, Slow vs. Fast-Twitch Fibers; Motor Units 00:46:36 Muscle Size vs. Muscle Strength, Quantity vs. Quality 00:50:56 Investigate: Muscle Quantity, Fat-Free Mass Index (FFMI) 00:56:21 FFMI, Elite Athletes, Muscle Mass 01:00:59 Muscle Asymmetry; Too Much Muscle Possible? 01:03:49 Interpret: Muscle Mass, FFMI Calculations & Percentiles 01:09:28 Tool: Intervene - Increase Muscle Mass, 72-Hour Rule 01:15:27 Sponsors: Maui Nui & Renaissance Periodization 01:17:51 Investigate: Muscle Quality & 4 Movement Principles 01:23:34 Muscle Quality & 3 Performance Principles  01:26:42 Interpret: Muscle Speed, Age 01:32:45 Muscle Power, Vertical Jump, Broad Jump 01:36:17 Muscle Strength, Powerlifting Elite, Bench Press, Leg Press, Grip Strength 01:44:05 Increasing Strength, Improve Health & Longevity 01:46:44 Tool: Intervene - Improve Muscle Quality, 4 Training Principles, 3-to-5 Rule 01:53:56 Zero-Cost Support, YouTube, Spotify & Apple Subscribe & Reviews, Sponsors, YouTube Feedback, Social Media 01:56:10 Conclusion from Dr. Andrew Huberman Disclaimer

Barbell Shrugged
[Muscle Plasticity] How to Build More Muscle, Faster w/ Dr. Christopher Fry, Anders Varner, and Doug Larson #751

Barbell Shrugged

Play Episode Listen Later Jun 12, 2024 60:18


Christopher Fry is an Associate Professor with tenure in the Department of Athletic Training and Clinical Nutrition and the Co-Director for the Center for Muscle Biology at the University of Kentucky. Chris completed a B.S. in Biology at Baylor University (2006), Ph.D. in biomedical sciences at the University of Texas Medical Branch (UTMB, 2011) and postdoctoral training in muscle physiology at the University of Kentucky (2014). Chris's research focuses on elucidating the mechanisms that regulate skeletal muscle plasticity to establish interventions to maintain strength and function during conditions of muscle wasting. Over the course of his career, he has created a focused research program that bridges targeted mechanistic approaches to clinical translation. Chris's work spans the translational spectrum, from targeted genetic strategies in pre-clinical models to randomized controlled trials. He has competed as an amateur bodybuilder and enjoys working out, traveling, cooking and spending time with his wife and son. Work with RAPID Health Optimization Dr. Christopher Fry on X Anders Varner on Instagram Doug Larson on Instagram Coach Travis Mash on Instagram

The Daily Zeitgeist
WE Might Be Giants? Testicular Plasticity 05.24.24

The Daily Zeitgeist

Play Episode Listen Later May 24, 2024 63:01 Transcription Available


In episode 1682, Jack and Miles are joined by host of More Than A Movie, Alex Fumero, to discuss… Microplastics Found In Every Human and Dog Testicle Tested, Breaking News: …uhhh…Giants Built All The Cool Buildings Conspiracy Just Dropped? Hulu Is Making A Dating Show For Virgins and more! Microplastics Found In Every Human and Dog Testicle Tested Breaking News: …uhhh…Giants Built All The Cool Buildings Conspiracy Just Dropped? Hulu Is Making A Dating Show For Virgins Dating series for virgins slammed as ‘most dystopian' reality show yet LISTEN: Good Day by Theo CrokerSee omnystudio.com/listener for privacy information.

This Week in Microbiology
310: Starvation vs Dehydration: Who Loses, Who Wins?

This Week in Microbiology

Play Episode Listen Later May 12, 2024 58:38


TWiM explores the plasticity of the adult human small intestinal stoma microbiota, and survival and rapid resuscitation that permit limited productivity in desert microbial communities. Hosts: Vincent Racaniello, Michael Schmidt, Petra Levin and Michele Swanson. Subscribe to TWiM (free) on Apple Podcasts, Spotify, Android, RSS, or by email. Become a patron of TWiM. Links for this episode Plasticity of small intestinal stoma microbiome (Cell Host Micr) Desert microbial communities (Nat Comm) How soil microbes survive in the desert (Science Daily) Negev Desert (WikiCommons) Take the TWiM Listener survey! Send your microbiology questions and comments (email or recorded audio) to twim@microbe.tv

You Start Today with Dr. Lee Warren | Weekly Prescriptions to Become Healthier, Feel Better, and Be Happier.
Getting Better at Getting Better (The 9th commandment of Self-Brain Surgery)

You Start Today with Dr. Lee Warren | Weekly Prescriptions to Become Healthier, Feel Better, and Be Happier.

Play Episode Listen Later May 9, 2024 28:32 Transcription Available


What You're Doing, You're Getting Better AtToday, a look at the 9th commandment of Self-Brain Surgery: I must believe that what I'm doing I'm getting better at.Scripture: Psalm 19:14, Matthew 22:37, Psalm 51:17, II Corinthians 10:5The Ten Commandments of Self-Brain SurgeryI must relentlessly refuse to participate in my own demise.I must believe that feelings are not facts, they are chemical events in my brain.I must believe that most of my thoughts are untrue.I must believe that my brain is designed to heal (Ryker's Regular Legs)I must love tomorrow more than I hate how I feel right now. (No Tomorrow Tax! Corollary: I must not treat bad feelings with bad operations.)I must stop making an operation out of everything.I must not perpetuate generational thought or behavioral issues in my family or start any new ones.I must love my brain and live in such a way as to protect and improve it.I must believe that what I'm doing I'm getting better at.I must understand that thoughts become things.Leave a voicemail with your question or comment!Five Ways You Can Support this show:Pray for us!Subscribe, like, and share it with your friends! (We even have a YouTube channel!)Leave reviews and comments wherever you listen to podcasts!You can become a paid partner of the podcast and get special bonus episodes and lots more content by clicking here. Visit one of our affiliate partners and consider using their products (we use them every day):Improve your gut health, support your immune system, and protect your brain with Pique!Other Helpful Links:Click here to access the Hope Is the First Dose playlist of hopeful, healing songs!Be sure to check out my new book, Hope Is the First Dose!Here's a free 5-day Bible study on YouVersion/BibleApp based on my new book!Sign up for my weekly Self-Brain Surgery Newsletter here!All recent episodes with transcripts are available here! (00:01) - Introduction to Self-Brain Surgery (02:29) - Exploring the Brilliance of William James (04:57) - William James on the Plasticity of the Brain (11:28) - The Ninth Commandment: Believing in Improvement (16:19) - Locus Minoris Resistentes: Synaptic Scars (21:51) - God's Desire for Your Thoughts (23:43) - Thoughts Become Things (25:37) - Choosing to Get Better at Getting Better

The Human Upgrade with Dave Asprey
The Science Behind Memory - Dr. Charan Ranganath : 1152

The Human Upgrade with Dave Asprey

Play Episode Listen Later Apr 16, 2024 81:27


In today's episode you'll explore the complexities of memory with Dr. Charan Ranganath, a top expert in cognitive neuroscience. This episode takes you through the fascinating ways our brains record, process, and utilize memories to navigate daily life and shape our futures. You'll learn how memory impacts decision-making, the truth about common myths, and the role of groundbreaking research in our understanding of cognitive function. Dr. Ranganath shares insights from his book "Why We Remember," shedding light on the brain's ability to predict and prepare for what comes next. Whether you're a seasoned biohacker or just starting, this conversation offers valuable perspectives on the science of memory that will change how you think about your mind.Timestamp highlights (00:01:03) The Role of Memory in Shaping Our Reality (00:04:51) The Truth about Remembering and Forgetting (00:12:27) Psychedelics, Plasticity, and the Future of Memory Research (00:16:32) The Ethics of Memory Enhancement (00:21:10) Harnessing Memory for Predicting the Future (00:29:17) How Memory Evolves with Age (00:33:27) The Power of Pattern Recognition in Human Intelligence (00:38:34) Debunking Memory Myths with Dr. Ranganath (00:40:54) The Role of Diet and Lifestyle in Memory Preservation (00:50:18) What 'Spider Sense' Says About Our Predictive Brains (00:55:10) Building a Life of Meaningful Memories (00:59:42) How Long Would You Want to Live if Your Memory Stayed Intact? Sponsors Sunlighten | Head to Sunlighten.com/dave to save up to $600 STEMREGEN | Go to STEMREGEN.co/Dave for 20% off Resources Get your copy of 'Why We Remember' by Dr. Charan Ranganath Dave Asprey's NEW Book ‘Smarter Not Harder' is out now: https://daveasprey.com/books Follow Dr. Ranganath on Instagram: @TheMemoryDoc See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Optimal Living Daily
3022: Write A List Of All Your Desired Future Experiences by Benjamin Hardy on Personality Plasticity

Optimal Living Daily

Play Episode Listen Later Dec 28, 2023 13:31 Very Popular


Discover all of the podcasts in our network, search for specific episodes, get the Optimal Living Daily workbook, and learn more at: OLDPodcast.com. Episode 3022: Benjamin Hardy's insightful article encourages readers to envision and list their desired future experiences, emphasizing how this practice shapes our identity and enhances decision-making. He argues that anticipating future experiences, embracing new challenges, and reflecting on past experiences can lead to a more fulfilling and dynamic life. Read along with the original article(s) here: https://medium.com/mind-cafe/write-a-list-of-all-your-desired-future-experiences-c285f42e9b5a Quotes to ponder: "The most successful lives are those that have the most worthwhile experiences." "The best way to predict your future is to create it." "It's incredibly difficult, if not impossible, to make high-quality decisions in the present without having a clear sense of future. All actions lead to outcomes." Learn more about your ad choices. Visit megaphone.fm/adchoices

Huberman Lab
Robert Greene: A Process for Finding & Achieving Your Unique Purpose

Huberman Lab

Play Episode Listen Later Dec 4, 2023 191:17 Very Popular


In this episode, my guest is Robert Greene, multiple New York Times bestselling author and expert on human psychology and behavior both at the individual and group levels and in the context of relationships, careers, and society. We discuss how to find, pursue and achieve one's unique life purpose, and how to best learn from good and hard experiences along that journey. We discuss power dynamics in relationships, the different types of human communication and the interplay between seduction and vulnerability. We discuss how to find the right romantic partner, improve healthy self-awareness, the link between anxiety and creativity, and pick ideal mentors and role models. Robert also discusses his recent stroke and what he has learned from his near-death experience about motivation, urgency and appreciation for life. Listeners of all ages will benefit from Robert's insights on navigating the process of building a deeply purposeful life and enhancing one's relationship with the self, others and society.  For show notes, including referenced articles and additional resources, please visit hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman ROKA: https://roka.com/huberman Helix Sleep: https://helixsleep.com/huberman Waking Up: https://wakingup.com/huberman InsideTracker: https://insidetracker.com/huberman Momentous: https://www.livemomentous.com/huberman Timestamps (00:00:00) Robert Greene (00:01:58) Sponsors: ROKA, Helix Sleep & Waking Up (00:05:56) Mastery (The Book), Purpose (00:08:26) Finding Purpose, Childhood, Learning & Emotional Engagement (00:18:00) Early Interests, Delight & Discovery (00:22:50) Love vs. Hate Experiences & Learning (00:28:25) Self-Awareness, Frustration, Excitation (00:31:47) Sponsor: AG1 (00:33:18) Sublime Experiences, Real vs. False; Authenticity & Time (00:43:57) Power & Relationships; Purpose & Mastery (00:55:51) Seduction, Vulnerability, Childhood (01:07:04) Sponsor: InsideTracker (01:08:05) Power Dynamics & Romance; Equality, Love Sublime & Connection (01:18:42) Vulnerability in Relationships, Creativity; Social Media, Justice (01:29:45) Outrage, Control, “Art of Ignore” (01:33:50) Masculinity & Femininity (01:42:16) Picking Role Models; Purpose & Mentor Relationship (01:51:07) “Alive” Thinking; Anxiety & Creativity (01:58:55) Convergent Interests & Romantic Relationships (02:07:19) Self-Awareness, Core Values & Romantic Relationships (02:15:27) Non-Verbal Communication & Relationships (02:24:58) Eyes, Voice, Intuition & Seduction (02:28:38) Virtual World, Social Skills, Non-Verbal Communication (02:32:19) Self-Awareness & Intelligence, Artificial Intelligence (AI), Nuance (02:41:43) Human Brain, Plasticity (02:45:18) Stroke & Near-Death Experiences, Self, Time (02:55:49) Appreciation & Near-Death Experience, Urgency (03:01:36) “Death Ground” & Urgency (03:09:13) Zero-Cost Support, Spotify & Apple Reviews, Sponsors, YouTube Feedback, Momentous, Social Media, Neural Network Newsletter Disclaimer