Podcasts about palo alto

Wearing the CMO+ hat rewires the role. You pick up a second lane, your calendar tightens, and perceptions shift from “just the marketer,” a label no one should wear, to business leader.   The path is demanding, but when the plus lines up with company priorities and earns trust across the business, the impact is unmistakable.   In this episode, Drew sits down with Sandy Ono, EVP and CMO at OpenText, who leads global marketing across ten business units while also owning partnerships and alliances. She treats both as one go-to-market, aligning partners and the field around a single story, running the forecast together, and keeping a steady rhythm so co-selling and co-marketing stay aimed at the same targets.  Three Actions Behind Sandy's CMO+ Success: Mindset: Claim growth as the job and step closer to revenue through partnerships  Skillset: Learn forecasting, deal construction, and the weekly rigor of partner sales  Toolset: Build the operating rhythm that connects co-selling, co-marketing, and accountability at scale  Plus:  How to choose a plus that aligns with company growth priorities  How to juggle both roles with capacity planning and clear priorities  How to protect brand integrity while telling a shared story with partners  How to measure progress with sourced pipeline, influenced revenue, retention, and feedback loops into product Weighing a plus or already living one? You'll find proven moves here.   If you're a B2B CMO, you can meet Sandy and another 100 incredible marketing leaders at the CMO Super Huddle in Palo Alto, California on November 6th and 7th. She'll be speaking on a panel about how CMOs are leading the charge with GenAI.  For full show notes and transcripts, visit https://renegademarketing.com/podcasts/ To learn more about CMO Huddles, visit https://cmohuddles.com/

Bad Crypto, Blood Thirsty Zombie CPUs, Y2K38, Park Mobile, Palo Alto, Redis, Red Hat, Deloitte, Aaran Leyland, and more on the Security Weekly News. Visit https://www.securityweekly.com/swn for all the latest episodes! Show Notes: https://securityweekly.com/swn-518

Today, I am thrilled to connect with Dr. Elizabeth Yurth. Dr. Yurth is double board-certified, as a physician in physical medicine and rehabilitation in addition to anti-aging and regenerative medicine. With over 30 years of clinical experience, Dr. Yurth continues to lead the way in orthopedics, cellular and regenerative medicine, and the future of aging. In our conversation, we explore immunosenescence and its implications for longevity. We discuss the off-label utilization of medications, including low-dose naltrexone, rapamycin, and GLP-1s, and examine other types of peptides, growth hormone secretagogues, and thymic peptides. We speak about hormones and anabolics, highlighting the benefits of anabolics for the bone health of those with osteopenia and osteoporosis. Dr. Yurth also shares her favorite supplements and outlines the key elements for optimal brain health. This episode is the first of a series of conversations with Dr. Yurth. She will join us again to dive into cardiovascular disease and explore powerful ways to support healthy aging at the cellular level. IN THIS EPISODE, YOU WILL LEARN: Why the thymus gland shrinks with age and what that means for immunity How thymic peptides support immune health, healing, and recovery The role thymosin alpha-1 plays in modulating the immune system Why thymosin beta-4 must be cycled for safe healing support How IGF (Insulin-like Growth Factor) decline impacts muscles, joints, and the brain with aging How growth hormone secretagogues can safely raise IGF How BPC-157 (a gastric peptide) aids gut repair, musculoskeletal healing, and brain protection Why mitochondrial peptides matter for energy, recovery, and repair How anabolics support bone strength and recovery How creatine and choline support the brain and muscles Bio: Elizabeth Yurth, MD, ABPMR, ABAARM, FAARM, FAARFM, FSSRP, is Co-Founder and Chief Medical Officer of Boulder Longevity Institute, where she has been providing Tomorrow's Medicine Today to her clients since 2006.  Dr. Yurth obtained her Medical Degree from the University of Southern California Keck School of Medicine, completed her residency at the University of California – Irvine, and her Fellowship in Sports and Spine Medicine from Stanford-affiliated Sports Orthopedics and Rehabilitation (SOAR) in Palo Alto, CA., along with her 30 years as a practicing orthopedist specializing in sports and spine medicine.  Dr. Yurth has made it her mission to learn and share the latest scientific research on how to truly heal the body at the cellular level. She is Fellowship trained in Anti-Aging, Regenerative, and Cellular Medicine. She has completed +500 hours of CME training focused on Longevity, Nutrition, Epigenetics, Bioidentical Hormone Replacement Therapy, Regenerative Peptide Treatments, and Regenerative Orthopedic Procedures.  Dr. Yurth continues to serve as a thought leader in Cellular Medicine, speaking at longevity events across the world and teaching others through her position as a founding faculty member for Seeds Scientific Research and Performance Institute (SSRP), which leads the way in connecting the latest research to clinical practice. Connect with Cynthia Thurlow   Follow on X, Instagram & LinkedIn Check out Cynthia's website Submit your questions to support@cynthiathurlow.com Connect with Dr. Elizabeth Yurth On her website Dr. Yurth on Facebook The Boulder Longevity Institute on Facebook Dr. Yurth on Instagram The Boulder Longevity Institute on Instagram

“How are we going to show up in LLMs?”  That's the new CEO question keeping B2B CMOs on alert. As AI-powered search reshapes how buyers find answers, B2B brands need a new organic strategy—Answer Engine Optimization (AEO). In this episode, Drew Neisser brings together two AEO trailblazers: Guy Yalif (Webflow) and Omer Gottlieb (Salespeak). Together, they tackle what it really takes to earn your place in AI answers. Forget keyword stuffing—this is about understanding how LLMs ingest, rank, and cite information, and how B2B marketers can respond now. You'll learn how to earn placement in AI-generated answers by mastering the four pillars of AEO: Content: Answer real buyer questions clearly and concisely.  Technical: Make your site machine-readable.  Authority: Earn credibility where buyers AND models are looking.  Measurement: Track share of voice across critical questions, then iterate. Also in this episode:  What LLMs want—but often can't find—on B2B websites  How to build a question-driven content strategy using sales calls, support tickets, and win-loss data.  Why share of voice (across buyer questions) is the new metric for AI visibility.  How to serve two audiences at once: humans and machines 

Three Buddy Problem - Episode 66: We discuss drone sightings that shut down airports across Europe and what they reveal about hybrid warfare and the changing nature of conflict; Oracle ransomware/extortion campaign tied to unpatched E-Business Suite vulnerabilities and the company's muted response. Plus, the TikTok–Oracle deal and the strange role Oracle now plays in U.S. national security; OpenAI's Sora 2 launch and its implications for social media and human expression; Palo Alto's “Phantom Taurus” APT report, a follow-up on Cisco's ArcaneDoor disclosures, and the impact of the U.S. government shutdown on CISA. Cast: Juan Andres Guerrero-Saade (https://twitter.com/juanandres_gs), Ryan Naraine (https://twitter.com/ryanaraine) and Costin Raiu (https://twitter.com/craiu).

Episode summary Joe and Mary dive into how platform censorship and shifting algorithms have reshaped psychedelic media, why DoubleBlind moved to a “newsletter-first” model, and what that's revealed about true audience engagement. They reflect on the post-2024 MDMA decision headwinds, state-level policy moves (wins and losses), and how funding, politics, and culture continue to reconfigure the field. They also explore alternatives to alcohol, chronic pain research, reciprocity around iboga/ibogaine, and lessons from PS25 (MAPS' Psychedelic Science 2025). Highlights & themes From platforms to inboxes: Social and search suppression (IG/FB/Google) throttled harm-reduction journalism; DoubleBlind's pivot to email dramatically improved reach and engagement. Post-MDMA decision reality: Investment cooled; Mary frames it as painful but necessary growth—an ecosystem “airing out” rather than a catastrophic pop. Policy pulse: Mixed year—some state measures stalled (e.g., MA), others advanced (e.g., NM; ongoing Colorado process). Rescheduling cannabis may add complexity more than clarity. Censorship paradox: Suppressing education makes use less safe; independent outlets need community support to keep harm-reduction info visible. Chronic pain & long COVID: Emerging overlaps and training efforts (e.g., Psychedelics & Pain communities) point beyond a psychiatry-only frame. Alcohol alternatives: Low-dose or occasional psychedelic use can shift habits for some; Mary stresses individual context and support beyond any single substance. Reciprocity & iboga: Rising interest (including from right-leaning funders) must include Indigenous consultation and fair benefit-sharing; pace of capitalism vs. community care is an active tension. PS25 field notes: Smaller, more manageable vibe than 2023; fewer “gold-rush” expectations; in-person dialogue beats online flame wars. Notable mentions DoubleBlind: Newsletter-first publishing; nurturing new writers and reported stories. Psychedelics & Pain Association / Clusterbusters: Community-driven models informing care and research (cluster headache protocols history). Books & media: Body Autonomy (Synergetic Press anthology); Joanna Kempner's work on cluster headaches - Psychedelic Outlaws; Lucy Walker's forthcoming iboga film. Compounds to watch: LSD (under-studied relative to MDMA), 2C-B, 5-MeO-DMT (synthetic focus), and broader Shulgin-inspired families.   Mary Carreon: [00:00:00] Okay, I'm gonna send it to my dad because he wants to know. Here Joe Moore: we go. Yeah, send it over. So, hi everybody. We're live Joe here with Mary Anne, how you doing today? Mary Carreon: I'm great Joe. How are you? Joe Moore: Lovely. I actually never asked you how to pronounce your last name does say it right? Mary Carreon: Yes, you did. You said it perfectly Joe Moore: lovely. Joe Moore: Um, great. So it's been a bit, um, we are streaming on LinkedIn, YouTube, Twitch X and Kick, I guess. Yeah. Kick meta. Meta doesn't let me play anymore. Um, Mary Carreon: you're in forever. Timeout. I got it. I got it. Yeah. Joe Moore: Yeah. I think they found a post the other day from 2017. They didn't like, I'm like, oh cool. Like neat, you Mary Carreon: know, you know. Mary Carreon: Yeah. That happened to me recently, actually. Uh, I had a post taken down from 2018 about, uh, mushroom gummies and yeah, it was taken down and I have strikes on my account now. So Joe Moore: Do you get the thing where they ask you if you're okay? Mary Carreon: Yes, with, but like with my searches though, [00:01:00] like if I search something or, or someone's account that has, uh, like mushroom or psychedelic or LSD or something in it, they'll be like, mm-hmm are you okay? Mary Carreon: And then it recommends getting help. So Joe Moore: it's like, to be fair, I don't know if I'm okay, but Yeah, you're like, probably not. I don't really want your help. Meta. Yeah. Mary Carreon: You're like, I actually do need help, but not from you. Thanks. Yeah, Joe Moore: yeah, yeah. Mary Carreon: So not from the techno fascists. Joe Moore: Oh, good lord. Yeah. Uh, we'll go there. Joe Moore: I'm sure. Mary Carreon: I know. I just like really dove right there. Sorry. Yeah. All right, so let's, Joe Moore: um, before we go, let's give people like a bit of, you know, high kicks on, on who is Mary, where you working these days and what are you doing? Mary Carreon: Yeah, thank you. My name is Mary Carryon and I am forever and first and foremost a journalist. Mary Carreon: I have been covering, I say the plant legalization spaces for the past decade. It's, it's been nine and a half years. Uh, on January 3rd it will be [00:02:00] 10 years. And I got my start covering cannabis, uh, at OC Weekly. And from there went to High Times, and from there went to Mary Jane, worked for Snoop Dogg. And then, uh, I am now. Mary Carreon: Double blind. And I have become recently, as of this year, the editor in chief of Double Blind, and that's where I have been currently sinking my teeth into everything. So currently, you know, at this moment I'm an editor and I am basically also a curator. So, and, and somebody who is a, uh, I guess an observer of this space more than anything these days. Mary Carreon: Um, I'm not really reporting in the same way that I was. Um, but still I am helping many journalists tell stories and, uh, I feel kind of like a story midwife in many ways. Just like helping people produce stories and get the, get the quotes, get the angles that need to be discussed, get the sentences structures right, and, um, uh, helping [00:03:00] sometimes in a visionary kind of, uh, mindset. Mary Carreon: So yeah, that's what I'm doing these days. Joe Moore: Oh, there it is. Oh, there you are. Love that. And um, you know, it's important to have, um, editors who kind of really get it from a lot of different angles. I love that we have a lot of alignment on this kind of, and the drug war thing and kind of let's, uh, hopefully start developing systems that are for people. Joe Moore: Yeah, absolutely. If you wanna just say that. Yeah, absolutely. Mary Carreon: Yeah, absolutely. Joe Moore: So, um, yeah, I almost 10 years in January. That's great. We um, it's so crazy that it's been that long. I think we just turned nine and a half, so we're maybe just a few, a few months shorter than your I love it. Plant medicine reporting career. Joe Moore: That's great. I love it. Um, yeah, so I think. I think one of the first times we chatted, [00:04:00] um, I think you were doing a piece about two cb Do you, do you have any recollection of doing a piece on two cb? Mary Carreon: I do, yes. Yes. Wait, I also remember hitting you up during an Instagram live and I was like, are you guys taking any writers? Mary Carreon: And you guys were like writers, I mean, maybe depending on the writer. Joe Moore: And I was like, I was like, I dunno how that works. Mary Carreon: Like me. Yeah. Joe Moore: Yeah. It was fun. It was fun to work with people like yourself and like get pieces out there. And eventually we had an awesome editor for a bit and that was, that was really cool to be able to like support young startup writers who have a lot of opinions and a lot of things to point out. Joe Moore: There's so much happening. Um, there was so much fraud in like wave one. Of kind of the psychedelic investment hype. There's still some, but it's lesser. Um, and it's really a fascinating space still. Like changing lives, changing not just lives, right? Like our [00:05:00] perspective towards nearly everything, right? Joe Moore: Yeah. Mary Carreon: Yes, absolutely. Absolutely. I mean, it's interesting because the space has matured. It's evolved. It's different than it was even, what a, I mean, definitely nine years ago, but even five years ago, even four years ago, even last year, things are different. The landscape is different than it was a year ago. Mary Carreon: And I, it's, it's interesting to see the politics of things. It's interesting to see who has money these days given like how hard it is just to kind of survive in this space. And it's interesting just to. Bear witness to all of this going down because it really is a once in a lifetime thing. Nothing is gonna look the same as it does now, as it, uh, then it will like in a, in a year from now or anything. Mary Carreon: So it's really, yeah. It's interesting to take account of all of this Joe Moore: That's so real. Uh, maybe a little [00:06:00] too real, like it's serious because like with everything that's going on from, um, you know, governance, governments, ai Yes. Drug policy shifts. Drug tech shifts, yes. There's so much interesting movement. Um, yes. Joe Moore: You, you know, you, you kind of called it out and I think it's really actually worth discussing here since we're both here on the air together, like this idea that the psychedelic market, not idea, the lived experience of the psychedelic market having shifted substantially. And I, I, I think there's a lot of causes. Joe Moore: But I've never had the opportunity to really chat with you about this kind of like interesting downturn in money flowing into the space. Mm-hmm. Have you thought about it? Like what might the causes be? I'm sure you have. Mary Carreon: Yeah. Yeah, I have. Yeah. I've thought about it. I mean, it's hard. Well, I don't know. I am really not trying to point fingers and that's not what I'm [00:07:00] trying to do here. Mary Carreon: But I mean, I think a lot of people were really hopeful that the FDA decision last June, not last June, the previous June, a year ago, 2024, June was going to open the floodgates in terms of funding, in terms of, um. In terms of mostly funding, but also just greater opportunities for the space and, uh, greater legitimacy granted to the psychedelic medicine space. Mary Carreon: Mm. And for those who might not know what I'm talking about, I'm talking about the, uh, FDA decision to reject, uh, MDMA assisted therapy and, um, that whole, that whole thing that happened, I'm sure if it, you didn't even have to really understand what was going on in order to get wind of that wild situation. Mary Carreon: Um, so, so maybe, yeah. You probably know what I'm talking about, but I, I do think that that had a great impact on this space. Do I think it was detrimental to this space? [00:08:00] I don't think so. We are in a growth spurt, you know, like we are growing and growing pains happen when you are evolving and changing and learning and figuring out the way forward. Mary Carreon: So I think it was kind of a natural process for all of this and. If things had gone forward like while, yeah, there probably would be more money, there would be greater opportunity in this space for people wanting to get in and get jobs and make a living and have a life for themselves in this, in this world. Mary Carreon: I don't know if it was, I don't know if it would necessarily be for the betterment of the space in general for the long term. I think that we do have to go through challenges in order for the best case scenarios to play out in the future, even though that's difficult to say now because so many of us are struggling. Mary Carreon: So, but I, but I have hope and, and that statement is coming from a place of hope for the future of this space and this culture. Joe Moore: Yeah. It's, um, I'm with [00:09:00] you. Like we have to see boom bust cycles. We have to see growth and contraction just like natural ecosystems do. Mary Carreon: Absolutely, absolutely. It has to be that way. Mary Carreon: And if it's not that way, then ifs, if. It's, it like what forms in place of that is a big bubble or like a, a hot air balloon that's inevitably going to pop, which, like, we are kind of experiencing that. But I think that the, I think that the, um, the, the air letting out of the balloon right now is a much softer experience than it would be if everything was just like a green light all the way forward, if that makes sense. Mary Carreon: So, Joe Moore: right. And there's, there's so many factors. Like I'm, I'm thinking about, uh, metas censorship like we were talking about before. Yes. Other big tech censorship, right? Mm-hmm. SEO shifts. Mary Carreon: Oh. Um, yes, absolutely. Also, uh, there were some pretty major initiatives on the state level that did not pass also this past year that really would've also kind of [00:10:00] helped the landscape a little bit. Mary Carreon: Um. In terms of creating jobs, in terms of creating opportunities for funding, in terms of having more, uh, like the perception of safer money flow into the space and that, you know, those, those things didn't happen. For instance, the measure for in Massachusetts that didn't go through and just, you know, other things that didn't happen. Mary Carreon: However, there have been really good things too, in terms of, uh, legalization or various forms of legalization, and that's in New Mexico, so we can't, you know, forget that there, and we also can't forget just the movement happening in Colorado. So there are really great things happening and the, the movement is still moving forward. Mary Carreon: Everything is still going. It's just a little more difficult than maybe it could have been Joe Moore: right. Yeah. Amen. Amen. Yes. But also, we Mary Carreon: can't forget this censorship thing. The censorship thing is a horse shit. Sorry. I'm not sure if I'm allowed to cuss, but it is, [00:11:00] but it is Joe Moore: calling it out and it's important to say this stuff. Joe Moore: And you know, folks, if you want to support independent media, please consider supporting Doubleblind and psychedelics today. From a media perspective, absolutely. We wanna wanna put as much out as we can. Yes. The more supporters we have, the more we can help all of you understand what's happening and yes. Joe Moore: Getting you to stay safer. Mary Carreon: Yeah, absolutely. And that's the whole difficulty with the censorship is that psychedelics today, and Doubleblind for instance, but also Lucid News, also other, uh, other influencers, other creators in the space, they like. What all of us are doing is putting out information that is ultimately creating a safer user experience. Mary Carreon: And so with the censorship, we are not able to do so anymore, which creates actually a lot of danger. So. Yeah, it's, it's difficult. The censorship is difficult, and if you are somebody who posts about psychedelics, I know that you know this and I am preaching to the choir. Joe Moore: Yeah. So can you talk a [00:12:00] little bit about you all at Double Blind made a major shift in the last number of months towards, uh, kind of not necessarily putting everything out there and, and kind of like, um, actually I don't even know the language you use. Joe Moore: What's the, what's the language you use for the kind of model shift you took on? Mary Carreon: Yeah, I mean, it's great. It's been a wild shift. It's been a wild shift. Um, what we are currently doing is we went to a newsletter first model, which instead of just posting onto a website for everyone to see, and then, um, you know, hopefully getting SEO hits and also posting on their, then posting those stories onto Instagram and Facebook and Twitter, and hoping to get traffic through social media. Mary Carreon: Uh, we decided that that was no longer working for us because it wasn't, um, because the censorship is so bad on, on social media, like on Instagram, for instance, and Facebook and Twitter, well, less on Twitter, [00:13:00] but still, nonetheless on social media, the censorship is so bad. And also the censorship exists on Google. Mary Carreon: When you Google search how to take mushrooms, double blinds is not even on. You know, our guide is not on the first page. It's like, you know, way the heck, way the heck down there. Maybe page 2, 3, 4, 5. I don't know. But, um, the issue, the issue with that, or, or the reason why rather that it's that way is because Google is prioritizing, um, like rehabilitation centers for this information. Mary Carreon: And also they are prioritizing, uh, medical information. So, like WebMD for instance. And all of these organizations that Google is now prioritizing are u are, are, are, are organizations that see psychedelic use through the lens of addiction or through drug drug abuse. So [00:14:00] again, you know, I don't know, take it for how you want to, I'm not gonna say, I'm not gonna tell anybody like what is the right way to use their substances or whatever. Mary Carreon: However, it's really important to have the proper harm reduction resources and tools available. Uh, just readily available, not five pages down on a Google search. So anyways, all of that said double blind was our traffic was way down. And it was looking very bleak for a while. Just we were getting kicked off of Instagram. Mary Carreon: We weren't getting any traffic from social media onto our website, onto our stories. It was a, it was a vicious kind of cycle downward, and it wasn't really working. And there was a moment there where Doubleblind almost shut down as a result of these numbers because there's a, like you, a media company cannot sustain itself on really low page views as a result. Mary Carreon: So what we [00:15:00] decided to do was go to a newsletter first model, which relies on our email list. And basically we are sending out newsletters three days a week of new original content, mostly, uh, sometimes on Wednesdays we repost an SEO story or something like that. Um, to just to engage our audience and to work with our audience that way, and to like to actually engage our audience. Mary Carreon: I cannot emphasize that enough because on Instagram and on Facebook, we were only reaching like, I don't know, not that many people, like not that many people at all. And all of that really became obvious as soon as we started sending out to our email list. And as soon as we did that, it was wild. How many, how many views to the website and also how many just open like our open rate and our click through rate were showing how our audience was reacting to our content. Mary Carreon: In other words. [00:16:00] Social media was not a good, in, like, was not a good indicator of how our content was being received at all because people kind of weren't even receiving it. So going to the newsletter first model proved to be very beneficial for us and our numbers. And also just reaching our freaking audience, which we were barely doing, I guess, on social media, which is, which is wild, you know, for, for a, an account that has a lot of followers, I forget at this exact moment, but we have a ton, double blind, has a ton of followers on, on Instagram. Mary Carreon: We were, we, we get like 500 likes or, you know, maybe like. I don't know. If you're not looking at likes and you're looking at views, like sometimes we get like 16 K views, which, you know, seems good, but also compared to the amount of followers who follow us, it's like not really that great. And we're never reaching new, like a new audience. Mary Carreon: We're always reaching the same audience too, [00:17:00] which is interesting because even with our news, with our, with our email list, we are still reaching new people, which is, which says just how much more fluid that space is. Mm-hmm. And it's because it's, because censorship does not at least yet exist in our inboxes. Mary Carreon: And so therefore email is kind of like the underground, if you will, for this kind of content and this type of material journalism, et cetera. So, so yeah. So it, it, it has been a massive shift. It is required a lot of changes over at double blind. Everything has been very intense and crazy, but it has been absolutely worth it, and it's really exciting that we're still here. Mary Carreon: I'm so grateful that Double-Blind is still around, that we are still able to tell stories and that we are still able to work with writers and nurture writers and nurture the storytelling in this space because it needs to evolve just the same way that the industry and the [00:18:00] culture and everything else is evolving. Joe Moore: Yeah, I think, I think you're spot on like the, when I watch our Instagram account, like, um, I haven't seen the number change from 107 K for two years. Mary Carreon: Absolutely. Same. And, um, same. Joe Moore: Yeah. And you know, I think, I think there's certain kinds of content that could do fine. I think, uh, psychedelic attorney, Robert Rush put up a comment, um, in response to Jack Coline's account getting taken down, um, that had some good analysis, um. Joe Moore: Of the situation. Go ahead. You had No, Mary Carreon: no, I'm just like, you know, I can't, when, when journalists are getting kicked off of these, of these platforms for their stories, for their reported stories, that's like, that is a massive red flag. And that's all I have to say. I mean, we could go into more, more details on that, but that is a [00:19:00] huge red flag. Joe Moore: Mm-hmm. Yeah. Um, for sure. The, I, yeah. And like I'm sure he'll get it back. I'm sure that's not for good, but I think he did. Okay, great. Mary Carreon: I think he did. Yeah. Yeah, I think he did. Joe Moore: Yeah. So thank you. Shout out to Jack. Yeah, thanks Jack. Um, and I think, you know, there's, there's no one with that kind of energy out there. Joe Moore: Um, and I'm excited to see what happens over time with him. Yeah. How he'll unfold. Absolutely unfold. Oh yeah. It's like, um. Crushing the beat. Mary Carreon: Oh yeah, absolutely. Especially the political, the political beat. Like, there's no, there's few people who are really tackling that specific sector, which is like mm-hmm. Mary Carreon: So exciting for a journalist. Joe Moore: Yeah. Um, so model shifting, like we all have to like, adapt in new ways. Kyle and I are still trying to figure out what we're gonna do. Like maybe it is newsletter first. Like I, I realized that I hadn't been writing for [00:20:00] years, which is problematic, um, in that like, I have a lot of things to say. Mary Carreon: Totally. Joe Moore: And nobody got to hear it. Um, so I started a substack, which I had complicated feelings about honestly. 'cause it's just another. Rich person's platform that I'm, you know, helping them get Andreessen money or whatever. And, you know, so I'm gonna play lightly there, but I will post here and there. Um, I'm just trying to figure it all out, you know, like I've put up a couple articles like this GLP one and Mushrooms article. Mary Carreon: I saw that. I saw that. Really? And honestly, that's a really, like, it's so weird, but I don't, like, it's such a weird little thing that's happening in the space. I wonder, yeah, I wonder, I wonder how that is going to evolve. It's um, you know, a lot of people, I, I briefly kind of wrote about, um, psychedelics and the GLP, is that what it is? Mary Carreon: GLP one. Joe Moore: GLP one. Say Ozempic. Yeah, just, yeah, Ozempic. Yeah, exactly. Mary Carreon: Yeah, exactly. I wrote about [00:21:00] that briefly last year and there were a bunch of people like obviously horrified, which it is kind of horrifying, but also there's a bunch of people who believe that it is extremely cutting edge, which it also is. Mary Carreon: So it's really interesting, really fascinating. Joe Moore: Yeah. Um, I remember Bernie Sanders saying like, if this drug gets as much traction as it needs to, it will bankrupt Medicaid. I guess that's not really a problem anymore. Um, but, but, uh, but so like naming it real quick, like it changed the way we had to digest things, therefore, like mushrooms get digested differently and, um, some people don't respond in the expected ways. Joe Moore: And then there was some follow up, oh, we, in the regulated model, we just do lemon tech. And then I was like, is that legal in the regulated model? And I, I don't know the answer still. Mm-hmm. Like there was a couple things, you know, if users know to do it, you know, I don't, I don't totally understand the regulated model's so strange in Oregon, Colorado, that like, we really need a couple lawyers opinions. Joe Moore: Right. I think Mary Carreon: yes, of course Joe Moore: the lawyers just gave it a [00:22:00] thumbs up. They didn't even comment on the post, which is, laughs: thanks guys. Um, Joe Moore: but you know, laughs: yeah. You're like, thank you. Joe Moore: Thanks and diversity of opinions. So yeah, there's that. And like GLP ones are so interesting in that they're, one friend reached out and said she's using it in a microdose format for chronic neuroinflammation, which I had never heard of before. Joe Moore: Whoa. And um, I think, you know, articles like that, my intent was to just say, Hey, researchers yet another thing to look at. Like, there's no end to what we need to be looking at. Abso Mary Carreon: Oh, absolutely, absolutely. You know, reporting on this space actually taught me that there's so much just in general that isn't being researched, whether that's in this space, but also beyond and how, um, yeah, just how behind, actually, maybe not, maybe behind isn't the right word, but it kind of feels from my novice and from my novice place in the, in the world and [00:23:00] understanding research, it's. Mary Carreon: Hard for me to see it as anything, but being behind in the research that we all really need, that's really going to benefit humanity. But also, you know, I get that it's because of funding and politics and whatever, whatever, you know, we can go on for days on all of that. Joe Moore: What's the real reason? What's the real reason? Joe Moore: Well, drug war. Mary Carreon: Yeah. Well, yeah, definitely the drug war. Nixon. Yeah. Yes, yes, definitely the drug war. Yeah. I mean, and just the fact that even all of the drug research that happens is, again, through the lens of addiction and drug abuse, so Joe Moore: mm-hmm. Hard to right. Yeah. Um, like ni a is obviously really ridiculous and, and the way they approach this stuff, and Carl Hart illustrates that well, and, Mary Carreon: oh man, yes, he does. Joe Moore: Like, I think Fadiman's lab in Palo Alto got shut down, like 67, 66 or 67, and like that's, you know, that was one of the later ones, Mary Carreon: right? And, Joe Moore: and like, Mary Carreon: and here we are. Joe Moore: The amount of suffering that could have been alleviated if we [00:24:00] had not done this is. Incalculable. Um, yes. Yes. Yeah. Mary Carreon: I mean the, yeah, it's hard to say exactly how specifically it would be different, but it's difficult to also not think that the fentanyl crisis and the opioid addiction rate and situation that is currently like plaguing the, the world, but particularly the United States, it's hard to think that it wouldn't be, like, it wouldn't be a different scenario altogether. Joe Moore: Right, right. Absolutely. Um, and it's, um, it's interesting to speculate about, right? Like Yeah. Yes. Where would we be? And Mary Carreon: I know, I know, I know, I know it is speculation. Absolutely. But it's like hard, as I said, it's hard not to think that things would be different. Joe Moore: Right. Right. Um, I like, there's two kind of quotes, like, um, not, this one's not really a quote. Joe Moore: Like, we haven't really had a [00:25:00] blockbuster psychiatric med since Prozac, and I think that was in the eighties or early nineties, which is terrifying. And then, um, I think this guy's name is James Hillman. He is kinda like a Jungian, um, educator and I think the title of one of his books is, we're a hundred Years Into Psychotherapy and the World is Still a Mess. Joe Moore: And I think like those two things are like, okay, so two different very white people approaches didn't go very far. Yes. Um, yes and laughs: mm-hmm. Joe Moore: Thankfully, I think a lot of people are seeing that. Mm-hmm. Um, finally and kind of putting energy into different ways. Um, Mary Carreon: yeah. Absolutely. I think, yeah, I mean, we need to be exploring the other options at this point because what is currently happening isn't working on many fronts, but including in terms of mental health especially. Mary Carreon: So mm-hmm. We gotta get going. Right? We [00:26:00] gotta get moving. Geez. Joe Moore: Have you all, have you all seen much of the information around chronic pain treatments? Like I'm, I'm a founding board member with the Psychedelics and Pain Association, which has a really fun project. Oh, that's interesting. Mary Carreon: Um, I've seen some of the studies around that and it's endlessly fascinating for obvious, for obvious reasons. Mary Carreon: I, um, we have a writer who's been working for a long time on a story, uh, about the chronic pain that has since. Become an issue for this, for her, for the writer. Mm-hmm. Um, since she had COVID. Mm-hmm. Since, since she is just like, COVID was the onset basically of this chronic pain. And, um, there she attended a psychedelics in pain, chronic pain conference and, uh, that has pretty much like, changed her world. Mary Carreon: Um, well, in terms of just the information that's out there, not necessarily that she's painless, but it's just, you know, offering a, a brand new, a brand new road, a brand new path that is giving her, [00:27:00] um, relief on days when the pain is, uh, substantial. laughs: Yeah. Mary Carreon: So that's interesting. And a lot of people are experiencing that as well. Joe Moore: Mm-hmm. So there's, there's a really cool set of overlap between the COVID researchers, long COVID researchers and the chronic pain people. 'cause there is Yes. This new science of pain that's yes. Our group, PPA put out like a really robust kind of training, um, for clinicians and researchers and even patients to get more educated. Joe Moore: And we're, we're getting, um, kind of boostered by cluster busters and we're kind of leveraging a lot of what they've done. Mary Carreon: Wait, what is a cluster buster? Joe Moore: Oh gosh. Um, so they're a 5 0 1 C3. Okay. Started with Bob Wald. Okay. Bob Wald is a cluster headache survivor. Oh, oh, oh, Mary Carreon: okay. Got it. Got it. Yes. So they're Joe Moore: the charity that, um, has been really championing, um, cluster headache research because they found a protocol [00:28:00] with mushrooms. Joe Moore: Yes, yes, yes. To eliminate. Mm-hmm. Yeah. Um, this really great, I Mary Carreon: love that. Joe Moore: This really great book was written by a Rutgers, um, I think medical sociologist or anthropologist psychedelic. Love laughs: that. Joe Moore: Joanna Kempner. Cool. Um, and it kind of talks about the whole, um, cluster busters saga, and it was, it was pretty cool. Joe Moore: Nice. So they've been at it for about as long as maps. Um, oh wow. Maybe a little earlier. Maybe a little later. Mary Carreon: I love that. Cool. I mean, yeah, that's really great. That's really great. Joe Moore: So we're copying their playbook in a lot of ways and Cool. We about to be our own 5 0 1 C3 and, um, nice. And that should be really fun. Joe Moore: And, uh, the next conference is coming up at the end of next month if people wanna check that out. Psychedelic. Nice. Mary Carreon: Nice, nice, nice. Cool. Joe Moore: Yeah, so that, like, how I leaned into that was not only did I get a lot of help from chronic pain with psychedelics and going to Phish shows and whatever, um, you know, I, and overuse for sure helped me somehow. Joe Moore: [00:29:00] Um, God bless. Yeah. But I, I like it because it breaks us out of the psychiatry only frame for psychedelics. Mm. And starts to make space for other categories. Mm-hmm. Is one of the bigger reasons I like it. Mary Carreon: Mm-hmm. Mm-hmm. Yes. Yes. Which, like, we need to be, we need to, we, no one else is gonna do it for us. We like the people in the space who are finding new uses for these substances need to be creating those, those pathways and those new niches for people to then begin studying, et cetera, and exploring and yeah. Mary Carreon: Making, making a proper avenue for, Joe Moore: right, right. And, you know, um, I don't know that this is a Maha thing, so No, I'm going there, I guess, but like, how do we kind of face squarely America and the world's drinking problems? Not [00:30:00] knowing what we know now about alcohol, you know what I mean? And then like, what are the alternatives? Joe Moore: You know, some, some writers out there on substack are very firm that everybody needs to not do any substance. And like all psychedelics are super bad and drugs are evil, you know, famous sub stackers that I won't name. But you know, like what is the alternative? Like, I, like we have to have something beyond alcohol. Joe Moore: And I think you've found some cannabis helpful for that. Mary Carreon: Yeah, I, you know, it's, it's interesting because it's, there are, there's definitely an argument to be made for the power of these substances in helping, I don't wanna, I don't wanna say curb, but definitely reduce the symptoms of, uh, wanting to use or to drink or to consume a specific substance. Mary Carreon: There's obviously there is an argument to be made. There are, there is ano another camp of people who are kind [00:31:00] of in the, in the, in the, in the realm of using a drug to get off of a drug isn't how you do it. However, and, and I do, it depends on the individual. It depends on the individual and the, and how that person is engaging with their own addiction. Mary Carreon: I think for whether or not the substances work, like whether psychedelics work to help somebody kind of get off of alcohol or get off of cocaine or stop using opioids or, you know, et cetera. Mm-hmm. However, I think like, when the situation is so dire, we need to be trying everything. And if that means, like, if, like, you know, if you look at the studies for like smoking cessation or alcohol use, mushrooms do help, psilocybin does help with that. Mary Carreon: Mm-hmm. But, you know, there's, there's a lot of, there's a lot of things that also need to happen. There's a lot of things that also need to happen in order for those, uh, that relief to maintain and to stick and to, uh, really guide [00:32:00] somebody off of those substances. Mm-hmm. It's not just the substance itself. Joe Moore: Right. So I'm, I'm explicitly talking like recreational alternatives, right. Like how do I Yeah. On per minute, like, am Anitas becoming helpful? Yeah, yeah. Are helpful and Yeah. Yeah. I think like even, um, normal. What we might call like normal American alcohol use. Like Yeah. That's still like, quite carcinogenic and like, um, absolutely. Joe Moore: We're kind of trying to spend less as a country on cancer treatments, which I hope is true. Then how do we, how do we develop things that are, you know, not just abstinence only programs, which we know for sure aren't great. Mary Carreon: Yeah. They don't work. Yeah. I don't, it's, it's difficult. Mm-hmm. It's difficult to say. Mary Carreon: I mean mm-hmm. I don't know. Obviously I, I, well, maybe it's not obvious at all for people who don't know me, but, you know, I exist in a, I exist in, in a world where recreational use is like, it's like hard to define what recreational use is because if we are using this, if we are using mushrooms or LSD even, or MDMA, [00:33:00] you know, there are so many, there's a lot of the therapy that can happen through the use of these substances, even if we're not doing it, you know, with a blindfold on or whatever and yeah, I think like. Mary Carreon: There is a decent swap that can happen if you, if you are somebody who doesn't wanna be, you know, having like three beers a night, or if you are somebody who's like, you know, maybe not trying to have like a bottle of wine at a night or something like that, you know, because like Americans drink a lot and a lot of the way that we drink is, um, you know, like we don't see it as alcoholism. Mary Carreon: Even though it could be, it could be that's like a difficult Joe Moore: potentially subclinical, but right there. Mary Carreon: Um, yeah. Yeah. It's like, you know, it's, um, we don't see it as that because everybody, a lot of people, not everybody, but a lot of people drink like that, if that makes sense. If you know mm-hmm. If you, if you get what I'm, if you get what I'm saying. Mary Carreon: So, you know, I do think that there's a lot of benefit that, I don't [00:34:00] know, having, like a, having a mushroom, having a mushroom experience can really help. Or sometimes even like low dose, low doses of mushrooms can also really help with, like, with the. Desire to reach for a drink. Yeah, totally. And, and AMS as well. Mary Carreon: I know that that's also helping people a lot too. And again, outside of the clinical framework. Joe Moore: Yeah. I'm, a lot of people project on me that I'm just like constantly doing everything all the time and I'm, I'm the most sober I've been since high school. You know, like it's bonkers that like Yeah. Um, and you know, probably the healthiest event since high school too. Joe Moore: Yeah. But it's fa it's fascinating that like, you know, psychedelics kind of helped get here and even if it was like For sure something that didn't look like therapy. Yeah, Mary Carreon: yeah, yeah, yeah. Absolutely. Absolutely. Yeah. I, I think, I think most of us here in this space are getting projected on as to like, you know, being like what Normies would consider druggies or something, or that we are just like, you know, high all the time. Mary Carreon: Um, [00:35:00] I know that that is definitely something that I face regularly, like out in the world. Um, but, you know, I would also, I would also argue that. Uh, like mushrooms have completely altered my approach to health, my approach to mental health, and not even having to consume that, you know, that substance in order or that, you know, that fun fungi, in order for me to like tap into taking care of my mental health or approaching better, uh, food options, et cetera. Mary Carreon: It's kind of like what these, it's like how the mushrooms continue to help you even after you have taken them. Like the messages still keep coming through if you work with them in that capacity. Right. And yeah, and also same with, same with LSD too. LSD has also kind my experiences with that have also guided me towards a healthier path as well. Mary Carreon: I, I understand that maybe for some people it's not that way, but, um, for me that substance is a medicine as well, [00:36:00] or it can be. Joe Moore: Yeah. Um, so. What are, what are some things popping up these days about like US drug policy that's like getting exciting for you? Like, are you feeling feeling like a looming optimism about a, a major shift? Joe Moore: Are you kind of like cautiously optimistic with some of the weird kind of mandatory minimum stuff that's coming up or? Mary Carreon: Yeah. Yeah. I mean, I know that there was a huge, a, a pretty huge shift over at the DEA and I wish I remembered, I wish I remembered his name. The new guy who's now, I believe the head of the DEA, I don't know enough information about it to really feel a way. Mary Carreon: However, I don't think that he's necessarily going to be serving us as a community here, uh, in the psychedelic space. I, you know, I just don't think that that's something that we can ever depend on with the DEA. Uh, I also don't think that [00:37:00] the DEA is necessarily going to be. All that helpful to cannabis, like the cannabis space either. Mary Carreon: Um, I know that, that Trump keeps kind of discussing or, or dangling a carrot around the rescheduling of cannabis. Um, for, he's been, he's been, but he's doing it a lot more now. He's been talking about it more recently. Uh, he says like, in the next like couple weeks that he's going to have some kind of decision around that, allegedly. Mary Carreon: But we will see also, I'm not sure that it's going to necessarily help anybody if we reschedule two. Uh, what from schedule one to schedule th two, three, schedule three. Joe Moore: Either way it's like not that useful. Right. Exactly. Mary Carreon: Yeah. Yeah, exactly. It's, um, just going to probably cause a lot more red tape and a lot of confusion for the state rec markets. Mary Carreon: So it's like something that we, it's like only ridden with unintentional, unintentional consequences. Unintended consequences. Mm-hmm. Because no one knows how it's really going to [00:38:00] impact anything, um, if, if at all. But I don't know. It's hard, it's hard to imagine that there won't be any, uh, like more complex regulatory issues for business owners and also probably consumers as well. Joe Moore: Hmm. Yeah. This guy's name's Terry Cole. Mary Carreon: Oh, the new DEA guy. Joe Moore: Yeah. Um, I don't know much about him. Terry. Yeah. Terry, I would love to chat. Mary Carreon: Yeah. Terry, let's talk. I'm sure your people Joe Moore: are watching. Yeah. So like, just let him know. We wanna chat. Yeah. We'll come to DC and chat it out. Um, yeah. It's, um, but yeah, I, Carl Hart's solution to me makes like almost most of the sense in the world to just end the scheduling system Absolutely. Joe Moore: And start building some sort of infrastructure to keep people safe. That's clearly not what we have today. Mary Carreon: No. But building an infrastructure around the health and wellness and uh, safety of [00:39:00] people is the exact opposite system that we have currently right now. Because also the scheduling system has a lot to do with the incarceration in the United States and the criminal just, or the criminal system. Mary Carreon: So, so yeah, like we can't disentangle the two really. Joe Moore: It just started, um, I feel negligent on this. Uh, synergetic press put out a book like a year or two ago called Body Autonomy. Mm-hmm. Um, did that one come across your desk at all? Mm-hmm. No. I wish basically contributed. Oh, nice. A number of people. So it's both like, um. Joe Moore: Drug policy commentary and then like sex work commentary. Oh, nice. And it was like high level, like love that really, really incredible love that detailed science based conversations, which is not what we have around this. Like, that doesn't make me feel good. So you should go to jail kind of stuff. Or like, I'm gonna humiliate you for real though. Joe Moore: Ticket. Yeah, Mary Carreon: yeah, yeah, yeah, yeah. Oh God. Uh, when you think about it like that, it just really also shows [00:40:00] just the uh, um, the level at which religion has also kind of fundamentally infused itself into the scheduling system, but also our laws, you know, like what you just said, this like, shame-based, I'm going to embarrass you and make you into a criminal when you know actually you are a law for the most part, a law abiding citizen, with the exception of this one thing that you're doing for. Mary Carreon: A, your survival and or your, like, your feeling good, wanting to feel good addressing pain. Um, there's a large, uh, like noise coming out of the front yard of my house right now. Hold on. Just a, it doesn't sound too bad. It doesn't sound too bad. Okay. Okay, good. Not at all. Not at all. Okay. Yeah, I had Joe Moore: people working on my roof all day and somehow it worked out. Joe Moore: Oh, good. Um, yeah. Um, yeah, it's, it's fascinating and I, I've been coming around like, I, I identify as politically confused, [00:41:00] um, and I feel like it's the most honest way I can be. Um, Mary Carreon: I am also politically confused these days, impossible to align with any, uh, party or group currently in existence at this exact juncture in American history. Joe Moore: I can't find any that I want to throw my dice in with. Nah. This idea of like fucking way being. Like what is the most humane way to do government as a way it's been put to me recently. And that's interesting. So it comes down to like coercion, are we caring for people, things like that. And um, I don't think we're doing it in a super humane way right now. Mary Carreon: Um, we, yeah, I am pretty sure that even if there was, I mean, I think that even if we looked at the data, the data would support that we are not doing it in a humane way. Joe Moore: So Mary Carreon: unfortunately, and Joe Moore: you know, this whole tech thing, like the tech oligarch thing, you kind of dropped at the beginning and I think it's worth bringing that back because we're, we're on all [00:42:00] these tech platforms. Joe Moore: Like that's kind of like how we're transmitting it to people who are participating in these other platforms and like, you know, it's not all meta. I did turn on my personal Facebook, so everybody's watching it there. I hope. Um, see if that count gets, Mary Carreon: um, Joe Moore: but you know, this idea that a certain number of private corporations kind of control. Joe Moore: A huge portion of rhetoric. Um, and you know, I think we probably got Whiffs of this when Bezos bought Washington Post and then Yes. You know, Musk with X and like yes. You know, is this kind of a bunch of people who don't necessarily care about this topic and the way we do, and they're like in larger topics too about humane government and like, you know, moving things in good directions. Joe Moore: Um, I don't know, thoughts on that rift there as it relates to anything you, wherever you wanna go. Yeah. Mary Carreon: Yeah. I mean, I don't think that they are looking at, I don't think that they are looking [00:43:00] at it the way that we are. I don't think that they can see it from their vantage point. Um, I think that like, in the, in a similar way that so many CEOs who run businesses have no fucking clue about what's actually happening in their businesses and the actual workers and, and employees of their businesses can tell them in more detail. Mary Carreon: Far more detail about what's actually happening on the, on the floor of their own business. Uh, I think that it is something like that. However, that's not to say that, you know, these, these CEOs who employ people who build the A algorithm are obviously guided to create the limitations on us as people who speak about drugs, et cetera, and are creating a algorithm that ultimately is looking at things in a very blanket way in terms of, uh, like we're probably seen on the same level as like drug dealers, if that makes sense. Mary Carreon: Which is obviously a much, you know, there's, [00:44:00] it's a very different thing. Um, so, you know, there's like these CEOs are giving directions to their employees to ultimately create systems that harm. Information flow and inform and, and like the information health of, of platforms and of just people in general. Mary Carreon: So it's hard to say because there's nuance there, obviously, but I would bet you that someone like Elon Musk doesn't really have a full grasp as to the, the nuances and details of what's even happening within, on the ground floor of his businesses. Because that's like, not how CEOs in America run, run, and operate. Mary Carreon: They're stupid companies. So, so yeah. And I feel like that, like, that's across the board, like that's across the board. That's how I, that's probably how Zuck is operating with Meta and Facebook, et cetera. And yeah, just likewise and across, across the whole, [00:45:00] across the whole spectrum. Joe Moore: Mm-hmm. Yeah. And I think, um, a thing. Joe Moore: Then as the people like, we need to keep looking at how can we keep each other informed. And that's kind of circling back to drug journalism like we do and like, um, other, other sorts of journalism that doesn't really get the press it deserves. Right. And I've been getting far more content that I find more valuable off of tragically back on Zucks platform like IG is getting me so much interesting content from around the world that no major outlet's covering. Mary Carreon: That's so interesting. Like what? Like what would you say? Joe Moore: Oh, um, uh, certain, um, violent situations overseas. Oh, oh, got it. Yeah, yeah, yeah. And, um, you know, that America's paying for, so like, you know, I just don't love that I don't have a good, you know, journalistic source I can [00:46:00] point to, to say, hey, like right. Joe Moore: These writers with names, with addresses, like, and offices here. Yes. You know, they did the work and they're held, you know, they're ethical journalists, so yes. You can trust them. Right. You know what I mean? Yes, Mary Carreon: yes. Yeah, yeah, yeah. I mean, all of this makes everything so much harder for determining, like, the censorship specifically makes it so much harder for the people to determine like, what's real, what's not. Mary Carreon: Because, because of exactly what you just said. Mm-hmm. Like, you know, we are, we are basically what that means, like what is required of the people and people who are consuming information is becoming a smart consumer and being able to determine what's real, what's not. How can we trust this individual? Mary Carreon: How can we not, which isn't analysis process that all of us need to be sharpening every single day, especially with the advent of AI and, uh, how quickly this, this type of content is coming at all of us. Like, especially if you're on TikTok, which many of us are, you know, like information comes flying at you 3000 miles an hour, and it's sometimes [00:47:00] really difficult to determine what's real, what's not, because AI is. Mary Carreon: AI is not where it's going to be, and it still is in its nascent phase. However, it's still pretty fucking good and it's still very confusing on there. So, so again, like the media literacy of the people needs to be sharpened every single day. We cannot be on there, we cannot be on the internet existing. Mary Carreon: That everything that we are seeing is real. Whether that's about, you know, these, um, the violence overseas, uh, happening at the hands of the United States, whether that is, uh, even drug information like, you know, et cetera, all of all of it. Or just like news about something happening at Yellowstone National Park or something that is happening in the, uh, at like. Mary Carreon: Um, like potential riots also happening at protests in downtown la, et cetera. Like all, all of it, we need to be so careful. And I think what that also, like, one way that [00:48:00] we can adjust and begin to develop our media literacy skills is talking to people maybe who are there, reaching out to people who are saying that they were there and asking them questions, and also sussing that out. Mary Carreon: You know, obviously we can't do that for all situations, but definitely some of them. Joe Moore: Yeah, absolutely. Like, Joe Moore: um, a quick pivot. Mm-hmm. Were you at PS 25? Mary Carreon: Yes, I was. What did I think? Uh, you know, I, I was running around like crazy at this one. I felt like I didn't even have a second to breathe and I feel like I didn't even have a second to really see anybody. I was like, worry. I was jumping from one stage to the next. Mary Carreon: However, I would say, uh, one of, one of the things that I have said and how I felt about it was that I felt that this, this event was smaller than it was two years ago. And I preferred that I preferred the reduction in size just because it was, uh, less over, less overwhelming [00:49:00] in an, in an already very overwhelming event. Mary Carreon: Um, but I thought that from the panels that I did see that everyone did a really great job. I thought that maps, you know, it's impressive that maps can put on an event like that. Um, I also was very cognizant that the suits were there in full effect and, uh, you know, but that's not unusual. That's how it was last time as well. Mary Carreon: And, um, I felt that there was Mary Carreon: a, uh, like the, the, the level of excitement and the level of like opportunity and pro, like the prosperous. The like, prospect of prosperity coming down the pipeline like tomorrow, you know, kind of vibe was different than last time. Mm-hmm. Which that was very present at the one, two years ago, uh, which was the last PS psychedelic science. Mary Carreon: Yeah. Um, anyways. Yeah. But it was, you know, it was really nice to see everybody. [00:50:00] I feel like in-person events is a great way for everybody in the psychedelic space to be interacting with each other instead of like keyboard warrioring against each other, you know, uh, over the computer and over the internet. Mary Carreon: I think that, um, yeah, uh, being in person is better than being fighting each other over the internet, so, yeah. Joe Moore: Mm-hmm. People seem to be a little bit more civil in person. Mary Carreon: Exactly. Exactly. Mm-hmm. And I think that that is something that we all need to be considering more often, and also inviting people from across the aisle to your events and creating peace, because in person it's a little different than it is. Mary Carreon: When you have the opportunity to, uh, yeah, like keyboard attack someone over the internet, it's like, yeah. It's just so silly. So silly. We look like fools. Like we look like absolute idiots doing that. And you know what? I cannot sit here and say that I haven't looked like an idiot. So, you know, it's like I'm not, I'm not talking from like a high horse over here, but, but you know, it's like, it's [00:51:00] better when it's in person. Mary Carreon: I feel like there's like more civil engagements that we can all have. Joe Moore: It's practice, you know? Yeah. We're learning. Yeah. We are. We should be learning, including us, and yes, of course. Um, I, I play a subtler game these days and, uh, you know, I, I, I, it's better when we all look a lot better in my opinion, because yes, we can inform policy decisions, we can be the ones helping inform really important things about how these things should get implemented and absolutely right. Joe Moore: Like, Mary Carreon: absolutely. Yeah, it does. It does. Nobody, any service, especially these medicines, especially these sacraments, especially these plants, these molecules, et cetera, if we are all sitting here fighting each other and like calling each other names and trying to dunk on one another, when like in reality, we are also all kind of pushing for the same thing more or less. Joe Moore: Mm-hmm. So a thing that [00:52:00] I, it's a, it's kind of a, I, I had a great time at PS 25. I have no, no real complaints. I just wish I had more time. Yeah, same. Um, same. Yeah. Our booth was so busy. It was so fun. Just good. And it was like, good. I, I know. It was really good. I'm trying to say it out loud. I get to talk at the conference before Rick did. laughs: Oh, oh, Joe Moore: the morning show they put us on at like seven 30 in the morning or something crazy. Oh my god. It was early. I dunno if it was seven 30. Mary Carreon: That's so early. That's so early. Joe Moore: Yeah, right. Like that's crazy. I got zero nightlife in That's okay. Um, I was not, I was there for work. Yeah, Mary Carreon: yeah. I was Joe Moore: jealous. I didn't party, but you know, whatever. Joe Moore: Yeah, yeah. Mary Carreon: I did not party this time really in the same way that I did at PS 20. Was it 2023? Joe Moore: 23, yeah. 23. I only stay up till 11 one night in 23. Nice. Mary Carreon: Okay. Um, okay. Joe Moore: So I behaved, I have a pattern of behaving. 'cause I like That's good. I'm so bent outta shape inside going into these things. I'm like, I know, I know. Joe Moore: And, and I'm like, oh, all [00:53:00] my friends are gonna be there. It's gonna be great. And then it's like, yeah. It's mostly friends and only a little bit of stress. Yeah. Um, yeah. Yeah, Mary Carreon: yeah. I had a, I had a great time. It was really good seeing everybody again. Like you, I wish that I had more time with people. Like there are people that I like didn't even see who are my friends, Joe Moore: so, which Yeah. Joe Moore: Which is sad. That's like a subtext in, in like the notes coming away from 25. Is that the, um, American Right, if we wanna call it that, is very interested in this stuff. Oh yeah. Like the Texas establishment. Oh yeah. Um, the Texas contingent, right? They're deep. They're real deep. Mm-hmm. I have, um, Mary Carreon: let's talk about that more. Mary Carreon: Yeah. So Joe Moore: it's optimistic in, in some sense that psychedelic science is getting funded more. By states. 'cause the feds aren't stepping up. Right. I love that. Right. Yeah. Like, Hey feds, look what we can do. And you can't somehow, and [00:54:00] then, um, we'll see if state rights stays around for a while longer, maybe, maybe not. Joe Moore: And then the other part is like, is there a slippery slope given the rhetoric around addiction and the rise in interest in iboga for compulsory addiction treatment with psychedelics or, or compulsory mental health treatments with psychedelics because of the recent, it's illegal to be a person without housing. Joe Moore: Um, and you're gonna get put in treatment. Mm. Like, that's now a thing. So like, I don't know, I don't think forced treatment's good at all. I, and I don't think like, um, like the data is something like 15% effective, maybe less. Right. Right. It's not a good use of money. I don't know. We're, let's, I. You can go there if you want, and riff on that, or if you wanna talk about like, Texas, um, Arizona more generally. Mary Carreon: Yeah. I mean, I will just say this, I also don't really believe that forced treatment is like good, you [00:55:00] know, data Joe Moore: says it's bad. Mary Carreon: Yeah. Yeah. I also, yeah, I mean, it's like, I don't know. Yeah, that's, it's complex. It's a complex issue. I also don't think it's good, but I also do think that we need a much better framework and foundation for like, if people do want the help, helping them get it. Mary Carreon: Much more easily and in a way that's going to be beneficial for them. Um, and I don't think that that system or that pathway currently exists as we saw in, uh, with, with, um, measure 1 0 9 and the failure of measure 1 0 9 or, or was it Measure 1 0 10, 1 10, measure one 10 in Oregon. Joe Moore: But did you see the response yesterday or two days ago? Joe Moore: No, I didn't. No, I didn't. I'll I'll send it to you later. Okay. So the university did the research, um, Portland State University did the research Yes. And said, Hey, look, there was actually 20 other things that were higher priority. Like that actually influenced this increase in overdoses, not our law. Mary Carreon: Right. Mary Carreon: Yes. It was really COVID for Okay. [00:56:00] Like for, yeah. Right. Absolutely. Also, there was not a. Like there was not a framework in place that allowed people to get off the street should they want to, or you know, like, like you just can't really have a, all drugs are legal, or small amounts of drugs are legal without also offering or creating a structure for people to get help. Mary Carreon: That, that's, you can't do one without the other. Unfortunately. That's just like a, that's faulty from the start. So that's all I'll really say about that. And I don't think that that had fully been implemented yet, even though it was something that wasn't ideal for the, um, for the, for the measure. And I believe it was measure one 10, not measure 1 0 9, to be clear. Mary Carreon: Measure one 10. Um, yes, but confirmed one 10 confirmed one 10, yes. Mm-hmm. Um, but yeah, uh, that's, you know, that's kind of what I'll say. That's what I'll, that's where I'll leave that portion. Mm-hmm. You know? Uh, but yeah, forced treatment. I don't know. [00:57:00] We can't be forcing, forcing people to do stuff like that. Mary Carreon: I don't know. It's not gonna, it's, yeah, it doesn't seem Joe Moore: very humane. Mary Carreon: Yeah. No. And it also probably isn't gonna work, so, Joe Moore: right. Like, if we're being conservative with money, like, I like tote, like to put on Republican boots once in a while and say like, what does this feel like? And then say like, okay, if we're trying to spend money smartly, like where do we actually get where we want to be? Joe Moore: And then sometimes I put on my cross and I'm like, okay, if I'm trying to be Christian, like where is the most, like, what is the most Christian behavior here in terms of like, what would the, you know, buddy Jesus want to do? And I'm just like, okay, cool. Like, that doesn't seem right. Like those things don't seem to align. Joe Moore: And when we can find like compassionate and efficient things, like isn't that the path? Um, Mary Carreon: compassionate and t. Yeah, even, I don't know, I don't know if it looks lefty these days, but Yeah, I know what you mean. Yeah, I know what you mean. I know what you mean. Yeah. [00:58:00] Yeah. Um, yeah, it's complicated. It's complicated, you know, but going back, kind of, kind of pivoting and going back to what you were talking about in regards to the subtext, some of the subtext of like, you know, where psychedelic medicine is currently getting its most funding. Mary Carreon: You know, I do believe that that was an undercurrent at psychedelic science. It was the, the iboga conversation. And there's, there's a lot, there's a lot happening with the Iboga conversation and the Iboga conversation and, um, I am really trying to be open to listening to everyone's messages that are currently involved in. Mary Carreon: That rise of that medicine right now? Um, obviously, yeah, we will see, we'll see how it goes. There's obviously a lot of people who believe that this is not the right move, uh, just because there's been no discussions with, uh, the Wii people of West Africa and, you know, because of [00:59:00] that, like we are not talking to the indigenous people about how we are using their medicine, um, or medicine that does like that comes from, that comes from Africa. Mary Carreon: Um, also with that, I know that there is a massive just devastating opioid crisis here that we need to do something about and drug crisis that we need to be helping with. And this medicine is something that can really, really, really help. Um, I find it absolutely fascinating that the right is the most interested party in moving all of this forward, like psychedelic medicine forward. Mary Carreon: And I, I currently have my popcorn and I am watching and I am eating it, and I am going to witness whatever goes down. Um, but I'm, I, I hope that, uh, things are moving in a way that is going to be beneficial for the people and also not completely leave behind the indigenous communities where this medicine comes from. Joe Moore: [01:00:00] Mm-hmm. Mary Carreon: We'll see how it goes. Yeah. We'll see how it goes. We'll see how it goes. It Joe Moore: would be lovely if we can figure it out. Um, I know, and I think, uh, Lucy Walker has a film coming out on Iboga. Mm. I got to see it at Aspen, um, symposium last summer, and it was really good. Mm. So I'm sure it'll be cut different, but it's so good and it tells that story. Joe Moore: Okay. Um, in a helpful way. I'm gonna, I, yeah. I always say I'm gonna do this. I'm like, if I have space, maybe I'll be able to email her and see if we can screen it in Colorado. But it's like a brilliant film. Yeah. Cool. This whole reciprocity conversation is interesting and challenging. And so challenging being one of the few countries that did not sign onto the Nagoya protocol. Joe Moore: Absolutely. We're not legally bound, you know, some countries are Mary Carreon: I know. Yes, yes, yes. So Joe Moore: we're, you know, how do we do that? How do we do that skillfully? We still haven't done it with, um, first Nations folks around their [01:01:00] substances. Um, I think mushrooms are a little flexible and account of them being global, um, from Africa to Ireland and beyond. Joe Moore: And, but you know, that's, we still want to give a nod to the people in Mexico for sure. Yeah, absolutely. Absolutely. Yeah. Um, yeah. Yeah, it's, I had some fun commentary there that I would love to flesh out someday. Uh, but yeah, it's not for today. Mary Carreon: Yeah, yeah, yeah. Um, there's, yeah, there's obviously, there's obviously a lot with the conversation of reciprocity here and, um, I know, I, I don't know. Mary Carreon: I, I, what I do know is that we need to be listening to the indigenous people, not just listening to them second, like secondhand or listening to them, uh, once we have moved something forward, like actually consulting with them as the process goes. And that, you know, the way that both parties move, indigenous folks and, uh, western folks move, uh, are at inherently different paces. Mary Carreon: And, [01:02:00] um, I just hope, and I wish, and I, I hope, I just hope that, uh, Western what, like the Western party, the western folks who are diving into these medicines. Slow the fuck down and listen and just are able to at least make one right move. Just one, just like you. Like it's, doesn't have to be this, it doesn't have to be that hard. Mary Carreon: Although the pace of capitalism usually propels, uh, the western folks at, at a much quicker rate than, u

McDonald's is rebooting Monopoly after nearly a decade - this time with a digital twist - as the fast-food giant looks to boost sales and drive customers to its app. R-J Hottovy, Head of Analytical Research at the Palo Alto-based foot traffic analysis firm Placer.ai, joins Andy Dahn on the WBBM Noon Business Hour with the details.

James sits down with cybersecurity pioneer HD Moore, the legendary founder of the Metasploit framework, whose journey from dumpster-diving teenager to cybersecurity pioneer was anything but easy.   HD recounts how Microsoft called his employer weekly trying to get him fired for releasing exploits — harassment that ultimately motivated him to "drop zero days continuously, forever, until it got normal." He shares tales of accidentally controlling satellite systems after following network hops too far, backdooring 7,000 systems through tainted warez, and spending $80,000 on his personal credit card to build the Rapid7 team when traditional corporate processes moved too slowly. From crawling through school windows at 5 AM to access Apple computers as a poor kid, to discovering that Palo Alto devices were leaking 5,000 customers' domain admin passwords to internet scanners, HD's stories illuminate the wild early days when vulnerability research was considered criminal activity rather than corporate necessity. Discover how he accidently destroyed his first self-built computer, why his ex-wife held a pile of cash as bail money ready during years of FBI visits, and how the Phrack IRC channel became an unlikely recruitment ground for his first cybersecurity job.

Drs Kaniksha Desai and Julie Ann Sosa discuss the 2025 American Thyroid Association guidelines for the management of differentiated thyroid cancer. This podcast is intended for healthcare professionals only. Kaniksha Desai, MD, Associate Professor of Medicine, Department of Endocrinology, Stanford School of Medicine, Palo Alto, California Julie Ann Sosa, MD, Professor, Department of Medicine, University of California, San Francisco (UCSF) To read a partial transcript or to comment, visit: https://www.medscape.com/index/list_15483_0

When I sit down with product leaders who've spent decades shaping how Silicon Valley builds products, I'm always struck by how their career arcs echo the very lessons they now teach. Michael Margolis is no exception.Michael started his career as an anthropologist, stumbled into educational software in the late 90s, helped scale Gmail during its formative years, and eventually became one of the first design researchers at Google Ventures (GV). For fifteen years, he sat at the intersection of startups and product discovery, helping founders learn faster, save years of wasted effort, and—sometimes—kill their darlings before they drained all the fuel.In our conversation, Michael didn't just share war stories. He laid out a concrete, repeatable framework for product teams—whether you're a PM at a FAANG company or a fresh hire at a Series A startup—on how to cut through noise, get to the truth, and accelerate learning cycles.This post is my attempt to capture those lessons. If you're an early to mid-career PM in Silicon Valley trying to sharpen your craft, this is for you.From Anthropology to Gmail: The Value of Unorthodox BeginningsMichael's path to Google wasn't a linear “go to Stanford CS, join a startup, IPO” narrative. Instead, he started in anthropology and educational software, producing floppy-disk learning titles at The Learning Company and Electronic Arts. That detour turned out to be foundational.“Studying anthropology was my introduction to usability and ethnography,” Michael told me. “It gave me a lens to look at people's behaviors not just as data points but as cultural patterns.”For PMs, the lesson is clear: don't discount the odd chapters of your own career. That sales job, that nonprofit internship, or that side hustle in teaching can become your secret weapon later. Michael carried those anthropology muscles into Gmail, where understanding human behavior at scale was just as critical as writing code.Actionable Advice for PMs:* Audit your own “non-linear” career experiences. What hidden skills—interviewing, pattern-recognition, narrative-building—could you bring into product work?* When hiring, don't filter only for straight-line resumes. The best PMs often bring unexpected perspectives.The Google Years: Scaling Research at Hyper-speedMichael joined Gmail in 2006, when it was still young but maturing fast. He quickly noticed how different the rhythm was compared to the slow, expensive ethnographic studies he had done for consulting clients like Walmart.com.“At Walmart,” he explained, “I had to compress these big, long expensive projects into something faster. Gmail demanded that same speed, but at enormous scale.”At Google, the prime “clients” for his research were often designers. The questions he answered were things like: How do we attract Outlook users? How do we make the interface intuitive enough for mass adoption?This difference matters for PMs: in big companies, research questions often start downstream—how to refine, polish, or optimize. In startups, questions live upstream: What should we build at all? Knowing where you sit in that spectrum changes the kind of research (and product bets) you should prioritize.Jumping to Google Ventures: Bringing UXR Into VCIn 2010, Michael made a bold move: leaving the mothership to become one of the very first design researchers embedded inside a venture capital firm. GV was trying to differentiate itself by not just writing checks but also offering operational help—design, hiring, PR.“I got lucky,” he recalled. “GV had already hired Braden Kowitz as their design partner, and Braden said, ‘I need a researcher.' That was my break.”Working with founders was a shock. They didn't act like Google PMs. “It was like they were playing by a different set of rules. They'd say, ‘Here's where we're going. You can help me, or get out of my way.'”That forced Michael to reinvent how he showed value. Instead of writing reports that might sit unread, he had to deliver insights in real-time, in ways founders couldn't ignore.The Watch Party Method: Stop Writing ReportsHere's where the gold nuggets come in. Michael realized traditional reports weren't cutting it. Instead, he invented what he calls “watch parties.”“I don't do the research study unless the whole team watches,” he said. “I compress it into a day—five interviews with bullseye customers, the whole team in a virtual backroom. By the end, they've seen it all, they're debriefing themselves, and alignment happens automatically. I haven't written a report in years.”Think about that. No 30-page decks. No long hand-offs. Just visceral, shared observation.Actionable Advice for PMs:* Next time you run a user test, insist that at least your core team attends live. Skip the sanitized recap slides.* At the end of a session, have the team summarize their top three takeaways. When they say it, it sticks.Bullseye Customers: Getting Uncomfortably SpecificOne of Michael's most powerful contributions is the bullseye customer exercise.“A bullseye customer,” he explained, “is the very specific subset of your target market who is most likely to adopt your product first. The key is to define not just inclusion criteria but also exclusion criteria.”Founders (and PMs) often resist narrowing. They want to believe their TAM is huge. But Michael's method forces rigor. He described grilling teams until they admit things like: Actually, if this person doesn't work from home, they probably won't care. Or if they've never paid for a premium tool, they won't convert.Example: Imagine you're building a new coffee subscription. Your bullseye might be: Remote tech workers in San Francisco, ages 25-35, who already spend $50+ per month on specialty coffee, and who like experimenting with new roasters. If your product doesn't delight them, it won't magically resonate with “all coffee drinkers.”Actionable Advice for PMs:* Write down both inclusion and exclusion criteria for your bullseye.* Add triggers: life events that make adoption more likely (e.g., new job, new diagnosis, move to a new city).* Recruit five people who fit it exactly. If they're lukewarm, rethink your product.Why Five Interviews Is EnoughMichael swears by the number five.“After three interviews, you're not sure if it's a pattern,” he said. “By five, you hit data saturation. Everyone sees the signal. Any more and the team is begging you to stop so they can make changes.”For PMs under pressure, this is liberating. You don't need 100 customer calls. You need five of the right customers, observed by the right team members, in a compressed timeframe.Multiple Prototypes: Don't Ask Customers to ImagineAnother Margolis rule: never show just one prototype.“If you show one, the team gets too attached, and the customer can only react. With three, I can say: compare and contrast. What do you love? What do you hate? I collect the Lego pieces and assemble the next iteration.”Sometimes those prototypes aren't even original mockups—they're competitor landing pages. As Michael joked: “Have you tested your competitor's prototypes? No? Then you've left something out.”Actionable Advice for PMs:* When exploring value props, mock up three different landing pages. Don't ask “Which do you prefer?” Instead ask: “Which elements matter most, and why?”* Treat mild praise as a “no.” Only visceral excitement counts as signal.Founders, Stubbornness, and the Henry Ford TrapI pressed Michael on what happens when founders dismiss customer feedback by invoking Henry Ford's famous line about “faster horses.”He smiled. “The beauty of bullseye customers is it forces accountability. If you told me these people are your dream users, and they shrug, then you can't hand-wave it away. Either change your customer definition or your product.”This is a crucial lesson for PMs who work with visionary leaders. Conviction is necessary, but unchecked conviction can sink a product. Anchoring on bullseye customers creates a shared contract that keeps both egos and hypotheses grounded.Bright Spots > Exit InterviewsWhen teams ask him to interview churned customers, Michael often refuses.“There are a bazillion reasons people don't use something,” he said. “It's inefficient. Instead, I go find the bright spots—the power users who love it. I want to know why they're on fire, and then go find more people like them.”This “bright spot” focus helps PMs avoid premature pivots. Instead of chasing every no, double down on the yeses until you understand the common thread.Case Study: Refrigerated Medications and ZiplineTo illustrate, Michael shared a project with Zipline, the drone-delivery company. They wanted to deliver specialty medications. The core question: was speed or timing more important?Through interviews, the bright spot insight emerged: refrigeration was the killer constraint. Patients didn't care about “fastest possible” delivery in the abstract. They cared about not leaving refrigerated drugs on their porch.That nuance completely changed the product and infrastructure design.For PMs, the takeaway is that sometimes the decisive factor isn't the flashy benefit you advertise (“we're the fastest!”) but a practical detail you only uncover through careful listening.AI and the Future of ResearchWe couldn't avoid the AI question. Has it changed his process?“I worry about how AI is creating distance between teams and customers,” Michael admitted. “If my bot talks to your bot and spits out a report, you miss the nuance. The power of research is in the stories, the details, the visceral reactions.”That said, he does use AI for quick prototype copywriting and summaries. But he insists on live team observation for the real work.For PMs, the advice is to use AI as an accelerant, not a replacement. Let it write the rough draft of your landing page copy, but don't outsource customer empathy to a transcript.What PMs Should Do Differently TomorrowLet's distill Michael's 15 years of wisdom into actionable steps you can implement this week:* Define your bullseye. Write down exact inclusion, exclusion, and trigger criteria.* Recruit five. Stop at five, but make them exact matches.* Run a watch party. Get your designer, engineer, and PM peers in the virtual backroom. No observers, no insights.* Prototype in threes. Landing pages are cheap. Competitor screenshots are free.* Look for visceral reactions. Anything less than “Wait, can I get this now?” is a polite no.* Study the bright spots. Find your power users and figure out what makes them glow.* Compress cycles. The whole exercise—recruit, test, learn—should take days, not months.Quotes Worth RememberingTo make these lessons stick, here are five quotes from Michael that every PM should tape to their desk:* “I don't do the research unless the whole team watches.”* “A bullseye customer is the very specific subset of your target market most likely to adopt first.”* “After five interviews, you hit data saturation. Everyone sees the pattern.”* “If you show one prototype, the team gets too attached. With three, you collect the Lego pieces.”* “Mild encouragement is a polite no. Only visceral excitement counts as yes.”My Takeaways as a Coach and PMTalking to Michael reinforced something I've seen in my own career: product failure often comes not from bad execution, but from weak learning cycles. Teams don't test the right people, don't synthesize together, and don't act quickly on what they learn.Michael's methods aren't magic—they're discipline. They compress time, sharpen focus, and force alignment. Whether you're building the next Gmail or the next startup idea in a Palo Alto garage, these principles apply.If you're an early to mid-career PM, start by practicing on a small scale. Don't wait for your manager to bless a massive UXR budget. Run a five-person watch party with your next prototype. You'll be surprised at how quickly the fog lifts.ClosingIf this resonated and you're looking for deeper guidance, I also work 1:1 with PMs and executives on career, product, and leadership challenges. You can learn more at tomleungcoaching.com.And if you haven't yet, I'd love your input on my Future of Product Management survey. It only takes about 5 minutes, and by filling it out you'll get early access to the results plus an invitation to a live readout with a panel of top product leaders. The survey explores how AI, team structures, and skill sets are reshaping the PM role for 2026 and beyond. Let's ship greatness. This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit firesidepm.substack.com

Highlights from this week's conversation include:Michaela's Career Journey and Entry into Impact Investing (1:06)Lessons from Early Impact Experiences (3:36)Misconceptions about Impact Investing and Returns (6:39)Lessons from Clean Energy Investments (10:11)Venture and Asset Class Inclusion in Impact (12:03)Capricorn's Ecosystem Building and Value Add (15:59)Current Client Questions and Market Backlash (17:49)Strategies and Dislocations in Capital Markets (19:39)Marie-Celine's Background and Role at Capricorn (22:40)Asset Class Commitments (25:10)GP Engagement and Inflection Points (26:49)Investment Excellence and Entrepreneurial Teams (29:01)LP Relationships and GP Support (31:17)Mission Alignment for GPs (34:02)Due Diligence, Regulatory Risk, and Diversification (35:49)Connecting with Capricorn and Parting Thoughts (37:19)Capricorn Investment Group is a $13B mission-aligned investment firm founded on the belief that sustainable investment practices can enhance risk-adjusted returns. With offices in New York City and Palo Alto, Capricorn invests across asset classes, from venture capital to GP staking, supporting scalable solutions to the world's most pressing problems. Learn more at www.capricornllc.com.Silicon Valley Bank (SVB), a division of First Citizens Bank, is the bank of the world's most innovative companies and investors. SVB provides commercial and private banking to individuals and companies in the technology, life science and healthcare, private equity, venture capital and premium wine industries. SVB operates in centers of innovation throughout the United States, serving the unique needs of its dynamic clients with deep sector expertise, insights and connections. SVB's parent company, First Citizens BancShares, Inc. (NASDAQ: FCNCA), is a top 20 U.S. financial institution with more than $200 billion in assets. First Citizens Bank, Member FDIC. Learn more at svb.com.Swimming with Allocators is a podcast that dives into the intriguing world of Venture Capital from an LP (Limited Partner) perspective. Hosts Alexa Binns and Earnest Sweat are seasoned professionals who have donned various hats in the VC ecosystem. Each episode, we explore where the future opportunities lie in the VC landscape with insights from top LPs on their investment strategies and industry experts shedding light on emerging trends and technologies. The information provided on this podcast does not, and is not intended to, constitute legal advice; instead, all information, content, and materials available on this podcast are for general informational purposes only. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Want ad-free episodes, exclusives and access to community Q&As? Subscribe to Forever Strong Insider: https://foreverstrong.supercast.comIn this episode, Dr. Gabrielle Lyon sits down with Dr. Teo Soleymani, a fellowship-trained skin cancer surgeon and dermatologist, to cut through the noise of the skincare industry. They discuss everything from viral trends like "glass skin" to the science behind hormones, sun protection, and the lifestyle factors that truly determine your skin's health and longevity.Dr. Teo Soleymani debunks common myths and provides actionable, no-nonsense advice on what to use—and what to avoid—to build a powerful, evidence-based skincare regimen. This conversation is a must-watch for anyone who wants to stop guessing about their skin and start seeing real results.Join the Forever Strong Menopause Challenge today and get your 4-week, science-based plan to build strength, improve sleep, and feel in control again: https://drgabriellelyon.com/forever-strong-menopause-challenge/Chapters:0:00 - Intro: K-Beauty, Multi-Step Routines & The Makeup Debate6:15 - The Dangers of Makeup & Environmental Toxins11:50 - The Shocking Effects of Hormones on Skin & Hair16:59 - How Testosterone & Estrogen Impact Your Skin22:58 - The Best Way to Use Hormones for Skin Health29:20 - The Rise of Social Media Doctors & Medical Misinformation33:24 - The TRUTH About Sun Exposure, Skin Cancer & Aging46:00 - The Crucial Role of Diet & Protein in Skin Health48:13 - Oral Collagen, Vitamin C & Skin Hydration54:12 - Treating Crepey Skin with Lasers & Topicals1:02:47 - Dr. Solommani's Perfect Anti-Aging Regimen1:14:03 - The Beef Tallow Debate & How to Choose a Moisturizer1:16:53 - Red Light Therapy for Skin & Hair Growth1:21:26 - The Truth About Minoxidil, PRP & Exosomes1:28:40 - The Best Oral Supplements for Internal Sun Protection1:34:01 - Sun Powder: An Internal Sunscreen1:40:56 - Final Thoughts & The Future of SkincareWho is Dr Soleymani:A Los Angeles native, Dr. Soleymani completed his undergraduate studies in Evolutionary Biology at UCLA. He went on to graduate from the University of California, Irvine School of Medicine, during which time he was awarded numerous accolades for academic excellence and was inducted into the prestigious Alpha Omega Alpha honor society, considered widely to be the highest award bestowed in medical school. Dr.Soleymani completed his internship at Cedars-Sinai Medical Center, where he was awarded the UCLA David Geffen School of Medicine Excellence in Teaching with Humanism Award. He then went on to complete his residency at Stanford University in Palo Alto, California, one of the world's most premier dermatology training programs. While at Stanford, Dr. Soleymani worked with world-renowned experts in cutaneous oncology and complex skin diseases and was the recipient of various academic awards and distinctions. This episode is brought to you by:Puori - Use code DRLYON for 20% off - https://puori.com/DRLYONARMRA - Use code DRLYON to get 15% off your first order - https://tryarmra.com/DRLYONBON CHARGE - Use code DRLYON to get 15% off your entire order - https://boncharge.com/DRLYONManukora - Get $25 off your Starter Kit at https://manukora.com/DRLYONFind Dr Soleymani at: Instagram: https://www.instagram.com/teosoleymanimdWebsite: https://www.californiadermatology.com/provider/teo-soleymani-md-faad-facmsFind Dr. Gabrielle Lyon at: Instagram:@drgabriellelyon TikTok: @drgabriellelyonFacebook: facebook.com/doctorgabriellelyonYouTube: youtube.com/@DrGabrielleLyonX...

Everyone knows about Linsanity. But in this episode, we take you back to Lin's childhood in Palo Alto, California where he was an undersized point guard who seemingly had no chance to make the NBA.CREDITSRick Loayza: Head researcher, writer, and voiceJacob Loayza: Editor, producer, and publisher MUSIC"Broken" by AJ PRO"Horizons" by Roa SPORTS HISTORY NETWORKsportshistorynetwork.comsportshistorynetwork.com/podcasts/basketball-history-101/ FACEBOOKm.facebook.com/Basketball-History-101-103801581493027/ BUSINESS CONTACTbballhistory101@gmail.comMentioned in this episode:Sports History Network Theme SongThis theme song was produced by Ron "Tyke" Oliver of Music Meets Sportz https://sites.google.com/view/sportsfanztastic/sports-history-network?authuser=0

Comdivision CEO Yves Sanfort comes to Palo Alto to work with VCF teams and talks about customer adoption across the globe, from Europe, now to America's and also a APJ perspecitve. Yves also covers the AI drivers in the enterprise and moving workloads back to VCF from other Vendors.

All of you are taking Harinām initiation today. You may also say, 'Why is it that we take an initiation into a free mantra? I can get this downtown Palo Alto at Lytton Plaza. They just have to go and find the youth Harinām kīrtan and hang around, right?' "They're not selling it down there. They're just giving it away free, and Lord Caitanya gave it away free. 'Why do I have to take all these vows?' Well, Viśvanāth Cakravartī Ṭhākur answers this question in his commentary to the sixth canto of the Śrīmad Bhāgavatam regarding the power of chanting the holy name. He says, 'If you can get the holy name from a Vaiṣṇav who's gotten it from a Vaiṣṇav, and that's the definition of a Vaiṣṇav—someone who has received the mantra from a Vaiṣṇav and is following the Vaiṣṇavs. That's why we call it Vaiṣṇavism.' He said, 'And you don't take it, then you're committing the third offense against the chant of the holy name.' In other words, you've got an attitude problem because you think you can go it alone. We can't go it alone. We consider that any advancement we make, any step we take, is enabled by the mercy of Lord Caitanya Mahāprabhu, who's Kṛṣṇa Himself, allowing us the highest, the biggest dispensation ever given in the history of the world, in the history of the universe, in the history of all the universes. 'Anarpita-carīṁ cirāt karuṇayāvatīrṇaḥ kalau' means there's the biggest sale of all time going on. Lord Chaitanya is giving this process through his Vaiṣṇava devotees. So we take the humble route, and we take the mantra, the Hare Kṛṣṇa mantra, from a devotee who's following a devotee who's following a devotee all the way back to Kṛṣṇa. And then Bhaktivinod Ṭhākur says in his Harinām Cintāmaṇi, 'Success of the highest kind is available to such a person.' If one chants Hare Kṛṣṇa, incidentally, one can be freed from many sins. 'jaya nāmadheya muni-vṛnda-geya he' 'jana-rañjanāya param akṣarākṛte' 'tvam anādarād api manāg udīritaḿ' 'nikhilogra-tāpa-paṭalīṁ vilumpasi' (Nāmāṣṭakam Verse 2) Somebody says it derisively, it can be cleared from many sins. But if someone becomes sincere and says that this is my sole purpose in life—to remember Kṛṣṇa and the process recommended by Śukadev Gosvāmī, by the Śrīmad Bhāgavatam—a whole canto is dedicated to it: how to be extricated from the material world, but much more than that, how to develop love for Kṛṣṇa. It's just by chanting the Lord's Names, what to speak of Caitanya Mahāprabhu coming and demonstrating how this is the process in Kali Yuga. Anyone can take. All of you who are doing this today will change the world by your stance of unwavering dedication to the chanting of 16 rounds every day, minimum, following the four regulative principles. ------------------------------------------------------------ To connect with His Grace Vaiśeṣika Dāsa, please visit https://www.fanthespark.com/next-steps/ask-vaisesika-dasa/ ------------------------------------------------------------ Add to your wisdom literature collection: https://iskconsv.com/book-store/ https://www.bbtacademic.com/books/ https://thefourquestionsbook.com/ ------------------------------------------------------------ Join us live on Facebook: https://www.facebook.com/FanTheSpark/ Podcasts: https://podcasts.apple.com/us/podcast/sound-bhakti/id1132423868 For the latest videos, subscribe https://www.youtube.com/@FanTheSpark For the latest in SoundCloud: https://soundcloud.com/fan-the-spark ------------------------------------------------------------ #spiritualawakening #soul #spiritualexperience #spiritualpurposeoflife #spiritualgrowthlessons #secretsofspirituality #vaisesikaprabhu #vaisesikadasa #vaisesikaprabhulectures #spirituality #bhaktiyoga #krishna

In this episode, we welcome editor Glen Scantlebury, ACE. Glen has worked on a variety of influential films such as Megalopolis, Dracula, The Cotton Club, The Godfather Part III, Armageddon, Con Air, The Rock, Lara Croft: Tomb Raider, The Texas Chainsaw Massacre (2003), Friday the 13th (2009), A Nightmare on Elm Street (2010), Tropic Thunder, and Palo Alto. In our chat, we hear about his pathway to editing features, his role in pioneering digital editing workflows, collaborating with Francis Ford Coppola, and much more. Glen also offers the next generation of creators various insights and recommendations on editing and storytelling. “The Making Of” is presented by AJA:Gear up: AJA just launched new techFlexibility is everything in production, which is one of many reasons to check out AJA's newest products. IP25-R bridges SMPTE ST 2110 networks and 4K SDI/HDMI infrastructure, UDC-4K scales between HD and 4K/UltraHD, and BRIDGE LIVE 12G-4 provides a multi-channel UltraHD IP video workflow bridge for remote production, streaming, video contribution, and more. Learn more.Next-Gen DIY Storage, UnleashedThe OWC Express 1M2 80G delivers over 6000 MB/s real-world performance using the latest USB4 v2 (80 Gb/s) interface, with Thunderbolt 5 compatibility for next-gen workflows. Choose a ready-to-run or DIY enclosure—upgradeable to 8 TB using NVMe M.2 SSDs. Its passive heatsink design ensures silent, consistent speeds, all in a bus-powered, palm-sized form factor. Explore hereThe Art of Editing “Andor” with Yan Miles, ACE: OWC Takes Home Two Future's Best of IBC2025 Show Awards:Both the OWC Thunderbolt 5 Dual 10GbE Network Dock and OWC Jellyfish S24 Earn Coveted Honor at IBCOther World Computing announced its OWC Thunderbolt 5 Dual 10GbE Network Dock and its OWC Jellyfish S24 have both been awarded a Future's Best of Show Award, presented at IBC2025 by TVBEurope. Read more here Introducing Ninja TX:Introducing Ninja TX, the all-new addition to the Ninja family. It's equipped with 12G-SDI and HDMI, so now you can monitor & record from any pro camera to ultra-fast CFexpress media or external USB-C storage. You also get built in Wi-Fi for C2C workflows and AirGluTM timecode for multicam projects, all in a lightweight, compact 5-inch form factor. Atomos Ninja TX is available for pre-order for only $999 at Videoguys.com. Learn more herePost|Production World NY 2025:We're proud to support Post|Production World NY 2025, October 22–23 at NAB Show New York. Join editors, filmmakers, and creators for two days of expert-led sessions in color grading, cinematography, workflows, and creative AI. Save 15% with code FMCP15. Get your pass herePodcast Rewind:Sept 2025 - Ep. 95…Sponsor “The Making Of” newsletter and reach 250,000 filmmakers, TV production pros, and content creators each week. For more info, email mvalinsky@me.com Get full access to The Making Of at themakingof.substack.com/subscribe

EVEN MORE about this episode!Grief is not something to “get over”—it's a lifelong journey of learning how to live while honoring the memory of those we love. In this powerful episode, grief experts Dr. Gloria Horsley and Dr. Heidi Horsley share compassionate wisdom on navigating loss, breaking free from unrealistic timelines, and embracing the personal process of creating a “new normal.”Together, we explore the emotional, biological, social, and spiritual dimensions of grief, and highlight the unique challenges faced by families who've lost loved ones in service roles such as the military and firefighting. Gloria and Heidi discuss the importance of peer-to-peer support through organizations like TAPS, share personal stories of resilience, and reflect on gender differences in grieving and remarriage.You'll learn how unresolved grief can resurface years later, how joy and laughter can coexist with sorrow, and how forgiveness and post-traumatic growth can bring deep healing and purpose. Above all, this conversation reminds us that grief is not linear—it is unique, unpredictable, and filled with moments of both pain and profound spiritual growth.Join us for this heartfelt discussion on love, connection, and the strength of community in the face of loss.Guest Biography:Heidi Horsley, PhD is a licensed psychologist, social worker, and bereaved sibling. She is the Executive Director and co-founder of the Open to Hope Foundation, and co-hosts the award-winning Open to Hope cable television show and podcast. An Adjunct Professor at Columbia University and an award-winning author of eight books, Dr. Heidi maintains a private practice in NYC and has been featured on numerous media outlets, including 20/20. She serves on the advisory boards of TAPS (Tragedy Assistance Program for Survivors), the Elisabeth Kübler-Ross Foundation, and Peace of Mind Afghanistan (POMA). For a decade, she worked with the FDNY-Columbia University Family Guidance Program, supporting families of firefighters lost in the 9/11 attacks. Her doctoral research focused on the sudden death of a sibling.Gloria Horsley, PhD is a licensed marriage and family therapist, clinical nurse specialist, and president/cofounder of the Open to Hope Foundation. She co-hosts the award-winning Open to Hope TV and podcast, and previously served on the faculty of the University of Rochester School of Nursing and the Academy of Intuition Medicine. Gloria has co-authored 10 books, contributed to numerous publications, and appeared on major media outlets including The Today Show. She is a member of the Forbes Nonprofit Council and serves on the advisory boards for the Tragedy Assistance Program for Survivors (TAPS) and the Elisabeth Kübler-Ross Foundation. Widowed after 60 years of marriage, she is the mother of four children (including a deceased son) and grandmother to 10. Gloria and her partner, Dr. Frank Powers, divide their time between Palo Alto, CA, and Scottsdale, AZ.Episode Chapters:(0:00:01) - Understanding Grief and Healing(0:14:20) - Navigating Loss and Moving Forward(0:24:19) - Grieving Without Set Stages(0:38:31) - Navigating Grief and Finding Joy(0:46:01) - Lessons in Grief and Spiritual Growth➡️Subscribe to Ask Julie Ryan YouTube➡️Subscribe to Ask Julie Ryan Español YouTube➡️Subscribe to Ask Julie Ryan Português YouTube➡️Subscribe to Ask Julie Ryan Deutsch YouTube➡️Subscribe to Ask Julie Ryan Français YouTube✏️Ask Julie a Question!

Every CMO wants alignment with their CEO. But all too frequently, things go sideways. It turns into chasing growth at any cost, drowning in acronyms, or scrambling to justify marketing's seat at the revenue table. What if the real secret isn't louder advocacy, but clearer translation, seeing the world the way your CEO does?  That's the perspective Rohini Kasturi brings as CEO of HG Insights. Fresh off two bold acquisitions in just a few months, HG Insights is redefining revenue growth intelligence and giving CMOs a new way to frame growth, retention, and efficiency. Rohini's advice: Stop playing defense on budget lines and start leading with business outcomes. In this episode:  How CMOs can connect their work to the three CEO obsessions: Growth, retention, and efficiency  Why spotting churn signals early matters as much as chasing pipeline  What it takes to balance efficiency with agility… without cutting corners Plus:  The role of revenue growth intelligence in shaping GTM strategy  How acquiring TrustRadius and MadKudu expands HG Insights' platform  Why every marketing move should tie back to revenue, even on a longer timeline  What CMOs gain by learning to speak the language of the boardroom If you want to know how CEOs really think and how CMOs can match them step for step, this one's for you! BONUS: HG Insights it THE Official GTM Partner of CMO Huddles and one of the Founding Sponsors of the 2025's CMO Super Huddle in Palo Alto. Rohini will join for a panel on The Future of GTM. With sharp strategic insight and deep empathy for the CMO's ever-evolving role, Rohini offers a rare CEO perspective on what it takes to drive smarter, more connected growth in 2025 and beyond.  For full show notes and transcripts, visit https://renegademarketing.com/podcasts/ To learn more about CMO Huddles, visit https://cmohuddles.com/

In the early to mid-2000s Palo Alto was rocked by a cluster of teen suicides. For Suicide Prevention Awareness Month, we're airing a documentary from audio reporter and producer I-Yun Chan, who traveled to Palo Alto to help her understand her own loss, and what it means to live on after someone losing someone to suicide. This story was edited by Shereen Marisol Meraji and was made in the audio program at UC Berkeley's Graduate School of Journalism. It was engineered by Chris Hoff. This episode discusses suicide. If you are experiencing thoughts of suicide, call or text 988 to reach the National Suicide Prevention Lifeline. Learn more about your ad choices. Visit megaphone.fm/adchoices

My guest today is Jonathan Siddharth, co-founder and CEO of Turing.Jonathan incubated Turing in Foundation Capital's Palo Alto office in 2018. Since then, it has grown into a multi-billion dollar company that powers nearly every frontier AI lab: OpenAI, Anthropic, Google, Meta, Microsoft, and others. If you've seen a breakthrough in how AI reasons or codes, odds are Turing had a hand in it.Jonathan has a provocative thesis: within three years, every white-collar job, including the CEO's, will be automated. In this episode, we talk about what it will take to reach artificial superintelligence, why this goal matters, and how the agentic era will fundamentally reshape work. We also dig into his founder journey: what he learned from his first startup Rover, how he built Turing from day one, and how his leadership style has evolved to emphasize speed, intensity, and staying in the details.Jonathan has been at the edge of AI for years, and he has the rare ability to translate what's happening at the frontier into lessons for builders today.Hope you enjoy the conversation! Chapters: 00:00 Cold open00:02:06 Jonathan's backstory: his experience at Stanford00:06:37 Lessons from Rover00:08:39 Early Turing: incubation at Foundation Capital and finding PMF00:13:52 Why Turing took off00:15:12 Evolving from developer cloud to AGI partner for frontier labs00:16:49 How coding improved reasoning - and why Turing became essential00:20:38 Founder lessons: building org speed and intensity00:23:33 Why work-life balance is a false dichotomy00:24:17 Daily standups, flat orgs, and Formula One culture00:25:15 Confrontational energy and Frank Slootman's influence00:29:50 Positioning Turing as “Switzerland” in the AI arms race00:34:32 The four pillars of superintelligence: multimodality, reasoning, tool use, coding00:37:39 From copilots to agents: the 100x improvement00:40:00 Why enterprise hasn't had its “ChatGPT moment” yet00:43:09 Jonathan's thoughts on RL gyms, algorithmic techniques, and evals00:46:32 The blurring line between model providers and AI apps00:47:35 Why defensibility depends on proprietary data and evals00:55:20 RL gyms: how enterprises train agents in simulated environments00:57:39 Underhyped: $30T of white-collar work will be automated

Ordinary Judean families cry out under crushing debt, famine, and heavy Persian taxes, while their own nobles and officials exploit them for profit. Nehemiah responds with righteous anger, confronting the elites in a public assembly and demanding immediate restitution. He calls them back to God's Law, reminds them of their covenant duty, and sets the example himself when, as Governor over Judea, he refuses the governor's food allowance and instead provides for many out of his own wealth.  The Rev. Stewart Crown, pastor of Trinity Lutheran Church in Palo Alto, CA, joins the Rev. Dr. Phil Booe to study Nehemiah 5.   To learn more about Trinity Lutheran, visit trinitylutheranpaloalto.com. From rubble to renewal, Nehemiah shows how the Lord rebuilds not just walls but hearts. Brick by brick and prayer by prayer, we follow God's people through repentance, courageous leadership, fierce opposition, covenant renewal, and joyful dedication. This verse-by-verse series keeps Law and Gospel front and center, tracing the story from burned gates to the greater Builder — Christ Jesus — who secures a city that cannot fall. Expect honest history, practical application, and the steady comfort of God's promises when the work is heavy and critics are loud. Thy Strong Word, hosted by Rev. Dr. Phil Booe, pastor of St. John Lutheran Church of Luverne, MN, reveals the light of our salvation in Christ through study of God's Word, breaking our darkness with His redeeming light. Each weekday, two pastors fix our eyes on Jesus by considering Holy Scripture, verse by verse, in order to be strengthened in the Word and be equipped to faithfully serve in our daily vocations. Submit comments or questions to: thystrongword@kfuo.org.

Lords: * John * Avery * Jay Topics: * Being known for one thing and trying to do a different thing * https://jtholen.bandcamp.com/album/new-active-object * Finding instruments on the street * Accidentally arguing with sauna guy Microtopics: * Many-Time Topic Lord John Mystery. * Talking the plunge into the Topic Lords discord. * An unspoken constant presence like Seymour Glass in the Glass Family novels. * The Once and Future Musician. * Putting a formant filter on your organ so you can play the organ on Zoom. * Why pouring hot water sounds different from pouring cold water. * The sound of boiling hot urine. * The top rated coffee shop in San Francisco on Yelp for seven months in a row. * Remaining your coffee shop after Mark Zuckerberg in hopes that he'll show up in person. * Trying to open up a coffee shop in late 90s San Francisco and only realizing too late that it's 2016. * ADA compliant seating. * Four-person episodes of Topic Lords. * A 6'5" guy trying to barter a half-used spray paint can for a cup of coffee. * The Menacing Barterer. * Aggressive Wimpy gladly paying you tomorrow for a hamburger today or else. * Aggressive Wimpy throwing a shoe at your espresso machine. * Your car accidentally becoming an art car. * Letting people spray paint your car until it's nothing but spray paint. * Calling 911 and explaining that the guy menacing you needs marijuana. * Being detained by Mark Zuckerberg's private security force. * Living near Mark Zuckerberg's house so you can do whatever your fixation with Mark Zuckerberg is. * Aggressive Barter Guy trying to barter a Porsche for a cup of coffee. * The $6 Porsche. * Tholen or Tholen. * A prog album constructed from Klik n Play samples. * When someone who does I've things decides to do something else. * The Mountain Goats novelizations. * Leonard Cohen's terrible poetry. * Thinking a song is deeply meaningful until you read the lyrics. * New Active Object. * Lunch Music. * Doing a thing for a long time and getting good at it. * Who has time to read a novel? * Having Game Boys Advance but still reading books sometimes. * Telling your teacher that you need to go to your job at NASA and they're like "oh you must be doing something important over there" * Working in the waterslide industry. * The Joy of Being the Secrets Guy. * Reading too much into it is the next Frog Fractions game. * Admitting to your wife that you found a digital piano on the curb. * The digital piano in the background of the Frog Fractions 2 pitch video. * Walking by a theremin at a party and it chirps at you like a proximity car alarm. * The Moog Etherwave. * Staring at your broken Omnichord. * A toddler whose first word is "mandolin." * Living Out Yonder. * The Roland Space Echo. * A cassette tape except there isn't any cassette, the tape is just kind of wriggling around in there. * Buying synthesizers from thrift shops that don't know how to tell whether synthesizers are broken. * The Two Organs Behind Me. * Ukelins. * Zither-esques. * Dulcimers vs. hammered dulcimers. * Looping your song and picking the notes that kind of sound like they belong. * A Xylophone For Jandek. * Feeling like you're taking to extremely accomplished people and you're just a weird little guy. * Who Is Sauna Guy?? * Stuck debating sauna guy while the venerated author with similar interests to yours is holding court in the next room. * Physics Philosophy guy talking about physics and philosophy. * An hour into the conversation, telling Sauna Guy that you don't even like being warm and he just stares at you. * The new way to joke about forum URLs. * Back when the Internet was full of exciting possibilities. * What topics turn you into Sauna Guy. * David Byrne sitting alone at the David Byrne art exhibit in Palo Alto. * We're All Sauna Guy Now. * Voting each other off the podcast. * Lightning round sudden death topics. * When the sunscreen finally makes it onto your cornea. * Not having a home page again but meaning to someday.

Fr. Seán ÓLaoire, born in Ireland, embarked on a journey of profound exploration and service. Armed with a B.Sc. degree in Mathematics from the National University of Ireland, he answered a higher calling, becoming ordained as a Catholic priest in 1972. His path led him to spend 14 transformative years in Kenya, where he immersed himself in diverse cultures and languages.Driven by a deep curiosity for the human spirit, Fr. ÓLaoire pursued advanced studies, earning an M.A. and Ph.D. in Transpersonal Psychology. Today, he channels his insights and expertise as a Licensed Clinical Psychologist in private practice, enriching the lives of those he encounters.A visionary and spiritual guide, Fr. ÓLaoire is the co-founder and Spiritual Director of "Companions on the Journey," a vibrant non-denominational community based in Palo Alto.Through this platform, he fosters unity, compassion, and growth among seekers from all walks of life.Fr. ÓLaoire's literary contributions resonate globally, transcending borders and languages. His thought-provoking works, including "Spirits in Spacesuits" and "Souls on Safari," delve into the depths of human existence, offering profound insights and perspectives. His latest endeavor, "Setting God Free: Moving Beyond the Caricature We've Created in Our Own Image," challenges conventional beliefs and invites readers to embark on a liberating journey of self-discovery and spiritual liberation.With each publication, Fr. ÓLaoire continues to inspire and empower individuals worldwide, bridging the gap between spirituality and psychology. His legacy is one of enlightenment, compassion, and a relentless pursuit of truth.Become a supporter of this podcast: https://www.spreaker.com/podcast/next-level-soul-podcast-with-alex-ferrari--4858435/support.

Food-forward convenience stores are stealing fast-food's breakfast customers in a big way. RJ. Hottovy, Head of Analytical Research at Palo Alto–based foot traffic analysis firm Placer.ai, joins Rob Hart on the WBBM Noon Business Hour to explain...

En 1969, à Palo Alto, Ron Jones, professeur d'histoire, lance une expérience pour montrer à ses élèves comment le fascisme peut naître. À partir d'un simple cours sur la discipline, il crée un mouvement fictif : La Troisième Vague, fondé sur l'obéissance, le collectif et l'action. Les élèves se prennent immédiatement au jeu, adoptent des règles strictes, des signes de ralliement et des slogans, sans se rendre compte qu'ils glissent dans un système autoritaire. En quelques jours, la classe double de taille, les dénonciations se multiplient, l'école entière est contaminée. Pris dans son propre rôle, Jones devient malgré lui le chef charismatique d'un mouvement réel. Pour mettre fin à la dérive, il orchestre une mise en scène finale qui confronte les élèves à la mécanique du totalitarisme. Cette expérience, longtemps passée sous silence, inspirera le film La Vague. Elle montre à quel point chacun peut être tenté de suivre… plutôt que de penser. Merci pour votre écoute Vous aimez l'Heure H, mais connaissez-vous La Mini Heure H https://audmns.com/YagLLiK , une version pour toute la famille.Retrouvez l'ensemble des épisodes de l'Heure H sur notre plateforme Auvio.be :https://auvio.rtbf.be/emission/22750 Intéressés par l'histoire ? Vous pourriez également aimer nos autres podcasts : Un jour dans l'Histoire : https://audmns.com/gXJWXoQL'Histoire Continue: https://audmns.com/kSbpELwAinsi que nos séries historiques :Chili, le Pays de mes Histoires : https://audmns.com/XHbnevhD-Day : https://audmns.com/JWRdPYIJoséphine Baker : https://audmns.com/wCfhoEwLa folle histoire de l'aviation : https://audmns.com/xAWjyWCLes Jeux Olympiques, l'étonnant miroir de notre Histoire : https://audmns.com/ZEIihzZMarguerite, la Voix d'une Résistante : https://audmns.com/zFDehnENapoléon, le crépuscule de l'Aigle : https://audmns.com/DcdnIUnUn Jour dans le Sport : https://audmns.com/xXlkHMHSous le sable des Pyramides : https://audmns.com/rXfVppvVous aimez les histoires racontées par Jean-Louis Lahaye ? Connaissez-vous ces podcast?Sous le sable des Pyramides : https://audmns.com/rXfVppv36 Quai des orfèvres : https://audmns.com/eUxNxyFHistoire Criminelle, les enquêtes de Scotland Yard : https://audmns.com/ZuEwXVOUn Crime, une Histoire https://audmns.com/NIhhXpYN'oubliez pas de vous y abonner pour ne rien manquer.Et si vous avez apprécié ce podcast, n'hésitez pas à nous donner des étoiles ou des commentaires, cela nous aide à le faire connaître plus largement. Hébergé par Audiomeans. Visitez audiomeans.fr/politique-de-confidentialite pour plus d'informations.

In this week's episode, Steve and Brad set the stage for a pivotal stretch in the Sounders' season. They preview Saturday's home clash against LA Galaxy and look ahead to next Tuesday's showdown at Inter Miami, breaking down the key matchups and what's at stake in this final stretch of the regular season. With the Western Conference standings tightening, the hosts dive into where the Sounders could – and should – finish as the postseason approaches.The episode also features an in-depth interview with goalkeeper Andrew Thomas. He reflects on his standout performances during the Leagues Cup, shares the story of how he first fell in love with soccer growing up in England, and recounts his college journey at Stanford. Thomas also discusses the mentorship he's received from club legend Stefan Frei, and lets listeners in on some of his favorite local spots in Palo Alto.A blend of tactical insights, personal storytelling, and playoff context – this episode is a must-listen for Sounders fans gearing up for a crucial run of matches.

Born in a Lincoln Park antique shop with a potbelly stove - then eventually becoming a publicly traded company - Chicago's Potbelly Sandwich Shop is now being sold to convenience store operator RaceTrac... RJ Hottovy, Head of Analytical Research at Palo Alto–based foot traffic analysis firm Placer.ai, joins Rob Hart on the WBBM Noon Business Hour to discuss...

September 1998 – Palo Alto, CA. Tetris co-creator Vladimir Pokhilko was found dead with a stab wound on the right side of his neck. His wife, Elena Fedotova, and 12-year-old son, Peter Pokhilko, were brutally killed. The case was ruled a murder-suicide, but the local Russian community insisted it was a Mafia hit. More than twenty years later, investigators are still searching for the truth of what happened. For bonus episodes and outtakes visit: patreon.com/generationwhySee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

FREE Training: https://www.govclose.comSchedule a Enrollment Consultation: https://www.govclose.com/enrollment-interviewGovClose Certification OVERVIEW: https://www.govclose.com/govclose-certification-programHow does a small cybersecurity company land a government contract with the U.S. Army worth $1.8 million? In this interview, Harold shares how he used the GovClose strategy to identify opportunities, build relationships with the Army's small business office, and execute a subcontracting strategy that opened the door to federal contracting success.We break down his journey from first outreach to contract award, and why help desk support and network security are some of the hottest federal spending categories right now. If you're trying to break into government contracting, subcontracting is one of the fastest ways to win early and scale from there.Watch this interview to learn:- How Harold went from training to a $1.8M Army contract- Why small business offices can be the key to success- The subcontracting strategy that works again and again- What it takes to scale a cybersecurity company in federal salesReach out to Harold:https://www.linkedin.com/in/harold-kwigova/Follow me on LinkedIn for free live training: https://www.linkedin.com/in/govcloseWant to start your own consulting business in federal contracting? Learn more at https://govclose.comTimestamps:00:00 – Introduction: Harold's $1.8M Army contract win01:00 – Using Army acquisition forecasts to find opportunities02:15 – How the Small Business Office opened the right doors03:00 – Harold's cybersecurity niche: network security & Palo Alto firewalls04:15 – From college football to government contracting06:00 – The subcontracting strategy that landed the contract07:15 – Breaking into the Army help desk and IT support arena08:30 – Why few companies bid on these overlooked contracts09:30 – Building relationships with contracting officers early11:00 – Hiring staff and executing on a multi-year Army contract12:15 – Scaling a small business in the government contracting market13:45 – The power of the GovClose community for teaming & scaling15:15 – Revenue goals and building a $15M+ pipeline18:00 – Certifications (8a, SDVOSB, etc.) and when they matter20:00 – Advice for entrepreneurs entering federal contracting21:30 – Why persistence, research, and mentorship are key23:00 – Final thoughts and Harold's vision for the future

Superpowers for Good should not be considered investment advice. Seek counsel before making investment decisions. When you purchase an item, launch a campaign or create an investment account after clicking a link here, we may earn a fee. Engage to support our work.Watch the show on television by downloading the e360tv channel app to your Roku, LG or AmazonFireTV. You can also see it on YouTube.Devin: What is your superpower?Chad: GritHemp is more than a crop—it's a solution. In today's episode, Chad Rosen, Founder and CEO of Victory Hemp Foods, shared how his company is revolutionizing agriculture and nutrition while supporting farmers and sustainable practices.Chad started Victory Hemp Foods in 2014, inspired by the legalization of industrial hemp and its potential to solve critical problems in the food industry. “Farmers needed a manufacturer who could bring their products to market,” Chad explained. His company processes hemp seeds to create nutrient-dense ingredients like protein powder and oil that are used by global food brands in everything from protein bars to beverages.The secret to Victory Hemp Foods' success lies in its patented process. “We separate the oil and protein into two fractions,” Chad said. This innovation produces a clean, lightly flavored protein powder rich in essential amino acids and a heart-healthy oil with the ideal omega-6 to omega-3 ratio. By valorizing all parts of the hemp seed, including turning the hulls into sweeteners, Victory Hemp Foods creates a sustainable, profitable model that benefits farmers and consumers alike.Hemp's environmental benefits are equally compelling. It promotes biodiversity, breaks pest and weed cycles, and can grow with less water compared to many other crops. Chad emphasized its potential: “Hemp can be a 20-million-acre crop,” he said, noting its ability to transform both farming and food production.Victory Hemp Foods is scaling its operations to meet growing demand. The company is currently raising capital through a regulated crowdfunding campaign on WeFunder, allowing community members to invest in its mission. “This is a vote of confidence,” Chad said, encouraging supporters to back regenerative agriculture and healthy food systems.Hemp is more than a niche ingredient; it's a key to a healthier, more sustainable future. Victory Hemp Foods is leading the way—and you can be part of it.tl;dr:Chad Rosen shared how Victory Hemp Foods creates sustainable, nutrient-dense products from North American hemp.The company's patented process transforms hemp seeds into protein powder, oil, and sweeteners.Hemp farming supports biodiversity, reduces environmental impact, and offers economic opportunities for farmers.Victory Hemp Foods is raising capital on WeFunder, inviting community investment in its mission.Chad emphasized his superpower, grit, as the key to overcoming challenges and driving innovation.How to Develop Grit As a SuperpowerChad identified his superpower as grit—the ability to persevere through challenges without giving up. “The ability to look at a letdown and turn it around…keeps you grinding,” he explained. Over more than a decade, Chad's persistence has allowed him to overcome obstacles, adapt to setbacks, and lead Victory Hemp Foods to success. He emphasized that grit is essential for entrepreneurs navigating uncertain paths.Illustrative Story:Three years ago, Chad faced a major setback when a potential investor backed out after six months of due diligence, citing concerns about the company's technology. This left Victory Hemp Foods without funding or a clear path forward. Instead of giving up, Chad and his team reimagined their process, developing a more efficient and profitable solution. The unexpected challenge forced them to create a breakthrough that became the foundation of their current success.Tips for Developing Grit:View setbacks as opportunities to learn and grow.Believe that every disappointment is a blessing in disguise.Stay focused on solving problems instead of dwelling on challenges.Surround yourself with a team of talented, supportive individuals.By following Chad's example and advice, you can make grit a skill. With practice and effort, you could make it a superpower that enables you to do more good in the world.Remember, however, that research into success suggests that building on your own superpowers is more important than creating new ones or overcoming weaknesses. You do you!Guest ProfileChad Rosen (he/him):Founder & CEO, Victory Hemp FoodsAbout Victory Hemp Foods: At Victory Hemp Foods, we cold press North Americas freshest hemp hearts into nutritionally dense protein and oil. Our ingredients are in use by the worlds top food brands that are making anything from nutrition bars to protein rich beverages for their customers who read the ingredient label, the nutritional panel, and ask questions about how ingredients are sourced.Website: victoryhempfoods.comInstagram Handle: @victoryhempfoodsOther URL: wefunder.com/victory.hemp.foods/joinBiographical Information: Since 2014, Chad has led the growth of Victory Hemp Foods as founder and CEO. Prior to founding Victory Hemp, Chad was VP of Vetrazzo recycled glass surfaces, an eventual division of Polycor North America. He was the recent past president of the Kentucky Hemp Industries Association (KYHIA) and board member of the Organic Association of Kentucky (OAK). He received his bachelor's degree in Business Administration from Marquette University and completed additional business coursework at the University of New Mexico's Anderson College of Business as well as the University of New Castle (Australia). A graduate of the Village Capital Agricultural Accelerator his network in the food system is far reaching at high levels in the private and public sectors. The White House invited Chad to represent Kentucky and Victory Hemp Foods at the Global Entrepreneurship Summit in Palo Alto, where he met with POTUS's Entrepreneurial Ambassadors and 700 other entrepreneurs from 170 countries to work on solving for some of the world most pressing issues here at home and abroad, including food security. He's dedicated to bringing hemp into the rural economy where sustainable economic development is a priority.LinkedIn Profile: linkedin.com/in/chadwrosenSupport Our SponsorsOur generous sponsors make our work possible, serving impact investors, social entrepreneurs, community builders and diverse founders. Today's advertisers include FundingHope, Rancho Affordable Housing (Proactive), Flower Turbines, and InnerSpace. Learn more about advertising with us here.Max-Impact MembersThe following Max-Impact Members provide valuable financial support:Carol Fineagan, Independent Consultant | Hiten Sonpal, RISE Robotics | Lory Moore, Lory Moore Law | Marcia Brinton, High Desert Gear | Mark Grimes, Networked Enterprise Development | Matthew Mead, Hempitecture |  Michael Pratt, Qnetic | Dr. Nicole Paulk, Siren Biotechnology | Paul Lovejoy, Stakeholder Enterprise | Pearl Wright, Global Changemaker | Ralf Mandt, Next Pitch | Scott Thorpe, Philanthropist | Sharon Samjitsingh, Health Care Originals | Add Your Name HereUpcoming SuperCrowd Event CalendarIf a location is not noted, the events below are virtual.Impact Cherub Club Meeting hosted by The Super Crowd, Inc., a public benefit corporation, on September 16, 2025, at 1:30 PM Eastern. Each month, the Club meets to review new offerings for investment consideration and to conduct due diligence on previously screened deals. To join the Impact Cherub Club, become an Impact Member of the SuperCrowd.SuperCrowdHour, September 17, 2025, at 12:00 PM Eastern. Devin Thorpe, CEO and Founder of The Super Crowd, Inc., will lead a session on "What's the Difference Between Gambling and Investing? Diversification." When it comes to money, too many people confuse speculation with true investing. In this session, Devin will explore what separates gambling from responsible investment practices—and why diversification is one of the most important tools for reducing risk and improving outcomes. Drawing on real-world examples and practical strategies, he'll help you understand how to evaluate opportunities, spread risk wisely, and think long-term about your portfolio. Whether you're new to investing, considering your first community round, or looking to refine your approach as a seasoned investor, this SuperCrowdHour will give you actionable insights to strengthen your decision-making. Don't miss this chance to sharpen your perspective and invest with greater confidence.Superpowers for Good Live Pitch, September 29, 2025. Hosted by Devin Thorpe on e360tv, this special event gives purpose-driven founders the chance to pitch their active Regulation Crowdfunding campaigns to a nationwide audience of investors and supporters. Selected founders will gain exposure to investors, national visibility across social and streaming platforms, and exclusive prizes from judges and sponsors—all at no cost to apply or pitch. Applications close September 8, 2025. Founders: Apply today to take the stage where capital meets impact!Community Event CalendarSuccessful Funding with Karl Dakin, Tuesdays at 10:00 AM ET - Click on Events.NEIGHBR Live Webinar, in partnership with FundingHope, will share NEIGHBR's story with a wider audience — September 3 at 11 AM EST. Reserve your spot today!Earthstock Festival & Summit (Oct 2–5, 2025, Santa Monica & Venice, CA) unites music, arts, ecology, health, and green innovation for four days of learning, networking, and celebration. Register now at EarthstockFestival.com.Regulated Investment Crowdfunding Summit 2025, Crowdfunding Professional Association, Washington DC, October 21-22, 2025.Impact Accelerator Summit is a live in-person event taking place in Austin, Texas, from October 23–25, 2025. This exclusive gathering brings together 100 heart-centered, conscious entrepreneurs generating $1M+ in revenue with 20–30 family offices and venture funds actively seeking to invest in world-changing businesses. Referred by Michael Dash, participants can expect an inspiring, high-impact experience focused on capital connection, growth, and global impact.If you would like to submit an event for us to share with the 9,000+ changemakers, investors and entrepreneurs who are members of the SuperCrowd, click here.We use AI to help us write compelling recaps of each episode. Get full access to Superpowers for Good at www.superpowers4good.com/subscribe

This week, we're backstage at Palo Alto Players' latest production, Gypsy. We chat with several cast members, including our very own Sarah, about their experiences so far. We also discuss their favorite numbers, costume pieces, and what makes this version special. The show opens this weekend and runs through mid-September. Head to paplayers.org to purchase your tickets now and take advantage of a special discount from our friends at TBA (theatrebayarea.org).

Brought to you by TogetherLetters & Edgewise!In this episode: U.S. government takes 10% stake in Intel, as Trump expands control over private sectorElon Musk is lying about Tesla's self-driving and I have the DMs to prove itMusk's xAI sues Apple, OpenAI alleging anticompetitive scheme harmed X, GrokPerplexity Will Share Revenue From AI Searches With PublishersApple in talks to use Google's Gemini AI to power revamped Siri, Bloomberg News reportsMalaysia Launches Ryt Bank -- The World's First AI-Powered BankMichigan Supreme Court Rules Unrestricted Phone Searches Violate Fourth AmendmentNothing busted using professional photos as Phone 3 samplesSpotify is adding DMsWhy MIT Study On Enterprise Market Is Pressuring AI StocksCanaries in the Coal Mine? Six Facts about the Recent Employment Effects of Artificial IntelligenceWeird and Wacky: Mark Zuckerberg gifted noise-canceling headphones to his Palo Alto neighbors because of the nonstop construction around his 11 homesWill Smith's concert crowds are real, but AI is blurring the linesRestaurant battles fake deals offered by Google AI: ‘It's coming back on us'Tech Rec:Sanjay -

00:00:00 – Power Outages & Alex Jones Madness The show kicks off with banter about coffee, power outages, and how this is "the one" episode to watch. Alex Jones clips are then featured—ranging from chaotic rants, bizarre Thomas Jefferson misquotes, and wild conspiratorial tangents about Santa costumes and secret grand juries. 00:10:00 – Red-Eyed Aliens & Sleep-Deprived Man The hosts tease a future segment about red-eyed alien abductions involving a Muslim-Christian couple in Australia. They also speculate on the Flatwoods Monster's glowing red eyes and mention the finale of The Secret of Skinwalker Ranch. Then, a story is discussed about a UK man who claims to have been unable to sleep for two years, detailing his horrifying physical and mental deterioration. 00:20:00 – Comets, Conspiracies & Star Trek Parallels The conversation continues about the sleepless man before shifting to a baffling space object called 3I-ATLAS. It's discussed as possibly being a probe or alien craft, with a supposed leaked NASA memo suggesting it's under intelligent control. The team humorously compares it to Star Trek plots involving alien communication. 00:30:00 – Bigfoot Corpse at the State Fair A man named “Snake” claims to have found and displayed a Bigfoot corpse at the New York State Fair. The hosts express skepticism, noting the suspicious nature of the body and lack of video evidence. Local news coverage is played, showing the man's enthusiastic claims about battling Bigfoots and showcasing the corpse to fairgoers. 00:40:00 – Critique of the Bigfoot Body & State Fair Highlights Further discussion of the suspect Bigfoot corpse ensues. It's described as looking like a glued-together arts and crafts project. The hosts then shift to reviewing the New York State Fair offerings—deep-fried food, rooster crowing contests, and odd musical acts. A humorous critique of tribute bands and bizarre fair events follows. 00:50:00 – Skull with a Stalagmite & Mayo Firestarter The show shifts to a 300,000-year-old skull found in Greece with a stalagmite growing through it, puzzling scientists. Then, a man in Spain is arrested for setting a café on fire after being denied mayonnaise. The team jokes about male rage, potential mayo clinics, and cultural condiment preferences. 01:00:00 – Stablecoins, Chinese Students & AI Mayhem Discussion jumps to financial headlines, including stablecoins potentially draining bank deposits and Donald Trump proposing to allow 600,000 Chinese students into U.S. colleges. The team jokes about “China” using an old Trump clip. News is also covered about a Saudi-built Islamic AI chatbot and a hacker who used AI to conduct a massive cyberattack. 01:10:00 – AI-Powered Cybercrime & Tacos The cyberattack details are expanded, noting how a hacker used AI to write ransomware demands and find exploitable data. Then, attention turns to a taco-eating contest in San Antonio offering a $10,000 prize. The sign-up has already closed, disappointing the hosts. Joe is humorously nominated to compete. 01:20:00 – Taco Contest Fallout & Zuckerberg's Bunkers Further complaints about the closed taco contest continue. The show then dives into Mark Zuckerberg's massive compound in Palo Alto, where he handed out noise-canceling headphones to neighbors due to constant construction. The hosts mock the billionaire's efforts to maintain privacy while disrupting the neighborhood with “hydro floors” and private schools. 01:30:00 – Zuckerberg's Noise Diplomacy The crew wraps up their critiques of Zuckerberg's sprawling estate, suggesting his gestures like wine and doughnuts to neighbors are tone-deaf. There's some light commentary on his bizarre bunker expansions and the absurdity of Silicon Valley billionaires. 01:40:00 – Orgy Dome Controversy at Burning Man The team discusses a controversy involving someone being kicked out of the “Orgy Dome” at Burning Man for witnessing something disturbing. They mock the corporatization of Burning Man, suggesting brands like Little Caesars or Taco Cabana might soon sponsor the orgy tent. An Instagram photo of the dome's condition is referenced, and there's satire about how far the festival has strayed from its roots. 01:50:00 – Pumpkin Spice Chaos & White Elephant Nightmares A bizarre story unfolds about someone ordering 25 pounds of pumpkin spice online, leading to jokes about spice jungles and white elephant gifts. The team riffs on absurd workplace gift exchanges, packages with suspicious wrapping, and household pumpkin spice overloads—flavored water, scented air, and even garden tools. The hosts end on this autumnal madness with a final round of laughs. Copyright Disclaimer Under Section 107 of the Copyright Act 1976, allowance is made for "fair use" for purposes such as criticism, comment, news reporting, teaching, scholarship, and research ▀▄▀▄▀ CONTACT LINKS ▀▄▀▄▀ ► Phone: 614-388-9109 ► Skype: ourbigdumbmouth ► Website: http://obdmpod.com ► Twitch: https://www.twitch.tv/obdmpod ► Full Videos at Odysee: https://odysee.com/@obdm:0 ► Twitter: https://twitter.com/obdmpod ► Instagram: obdmpod ► Email: ourbigdumbmouth at gmail ► RSS: http://ourbigdumbmouth.libsyn.com/rss ► iTunes: https://itunes.apple.com/us/podcast/our-big-dumb-mouth/id261189509?mt=2  

In today's episode, supported by Nuvation Bio, we spoke with Joel Neal, MD, PhD, and Christian Rolfo, MD, PhD, about the FDA approval of taletrectinib (Ibtrozi) for the treatment of patients with locally advanced or metastatic, ROS1-positive non–small cell lung cancer (NSCLC). Dr Neal is a professor of medicine in the Division of Oncology at the Stanford Cancer Institute at Stanford University in Palo Alto, California. Dr Rolfo is the director of the Division of Medical Oncology at The Ohio State University Comprehensive Cancer Center—James and a professor in the College of Medicine at The Ohio State University in Columbus. In our conversation, Drs Neal and Rolfo discussed the significance of this approval, key data from the pivotal phase 2 TRUST-I (NCT04395677) and TRUST-II (NCT04919811) trials, and taletrectinib's current role in the NSCLC treatment paradigm.

US Senator Sanders favors Trump plan to take stake in Intel and other chipmakersBernie: "If microchip companies make a profit from the generous grants they receive from the federal government, the taxpayers of America have a right to a reasonable return on that investment."Mark Zuckerberg gifted noise-canceling headphones to his Palo Alto neighbors because of the non-stop construction around his 11 homesCracker Barrel, under fire from Donald Trump Jr. and Steak n' Shake, apologizes to fans but won't drop new logo“If the last few days have shown us anything, it's how deeply people care about Cracker Barrel. We're truly grateful for your heartfelt voices,” the company said Monday in a statement on its website.“You've also shown us that we could have done a better job sharing who we are and who we'll always be.”On Monday, the Lebanon, Tennessee-based company emphasized that many things about Cracker Barrel won't change, including the rocking chairs on its front porches and vintage Americana and antiques scattered throughout its restaurants.Cracker Barrel also said it will continue to honor Uncle Herschel — the older man in the former logo, who represents the uncle of Cracker Barrel's founder — on its menu and on items sold in its stores.But Cracker Barrel said it also wants to make sure that the business stays fresh and attracts a new generation of customers.Maine's Populist Senate Candidate Thinks We Are in a New Gilded AgeAccording to Graham Platner, America has entered a new gilded age and needs a politics that can meet the moment. “I think the comparisons between the late 19th century and now are apt: vast amounts of wealth and regulatory structures that in no way, shape, or form keep that wealth in check,” pointing to the power people like Elon Musk and other prominent Silicon Valley leaders have over the current administration.He pointed to his state's famed and tightly regulated lobster industry as an example.“The state of Maine has passed laws over the years that have regulated the lobster industry in a very specific way, and it means there's one boat, one captain, one license. Fishing can only be conducted while the captain is aboard. This has entirely disincentivized consolidation,” he explained.“The result is a half-a-billion-dollar-a-year industry for the state of Maine that has almost no corporate ownership.”When presented with the alternative theory—that Maine should instead allow consolidation in its prize industry and redistribute wealth back to workers and their communities through other means—he bluntly dismissed its proponents. “Those people are full of shit. The distribution of resources needs to happen at the level where things are being produced.”Lisa Cook Says She Will Not Step Down From the Fed Board“I will not resign,” she said. “I will continue to carry out my duties to help the American economy as I have been doing since 2022.”Meta Defector Issues Devastating Psychological Takedown of Tech CEOsNick Clegg, a former Meta executive who left the company at the start of this year: "If you're accustomed to privilege, equality feels like oppression.""You'd think, wouldn't you, that if you were immensely powerful and rich like Elon Musk and all these other tech bros and members of that podcast community that you'd reflect on your good fortune compared with most other people?" Instead, Clegg seethed, they cry persecution."In Silicon Valley, far from thinking they're lucky, they think they're hard done by, [that] they're victims. I couldn't, and still can't, understand this deeply unattractive combination of machismo and self-pity."Red Lobster Is Betting on Black Diners With Its Brand ComebackCEO Damola Adamolekun, who took over the job last September, a 36-year-old Nigerian American, who is also credited with rescuing P.F. Chang's.Red Lobster has been a part of America's casual-dining landscape since the first location opened in Lakeland, Fla., in 1968. Just four years after the passage of the Civil Rights Act, many restaurants in the South were still segregated de facto. Red Lobster embraced diversity, opening its doors to Black customers and hiring Black workers.The ‘woke' words Democrats should cut from their vocabularyA new memo identifies 45 words and phrases for Democrats to avoid, alleging the terms turn voters off. They span six categories: Therapy-Speak (1/11: Triggering); Seminar Room Language (0/8); Organizer Jargon (1/8: Stakeholders); Gender/Orientation Correctness (1/8: Patriarchy); The Shifting Language of Racial Constructs (0/5); Explaining Away Crime (0/4)Korea passes boardroom reform, curbing chaebol powerSouth Korea has passed a significant boardroom reform aimed at curbing the power of the country's large family-owned conglomerates, known as "chaebol."Here are some key changes:Mandatory Cumulative VotingFor large listed companies with assets exceeding 2 trillion won (about $1.44 billion), a cumulative voting system is now required. This system allows minority shareholders to pool their votes and elect a representative to the board, giving them a greater voice in corporate governance.Increased Power for Audit CommitteesThe number of audit committee members elected separately from the controlling shareholders will increase from one to at least two. This strengthens the independence of the audit committee, which is responsible for overseeing financial reporting and internal controls.Broader Application of the "3% Rule"The "3% rule," which limits the voting power of the largest shareholders to 3% when electing audit committee members, will now be extended to independent directors. Previously, this cap only applied to internal directors.Extended Fiduciary Duty of DirectorsA previous amendment in July extended the fiduciary duty of directors to all shareholders, not just the company. This change is intended to prevent controlling families from making decisions that benefit themselves at the expense of minority shareholders."Outside Directors" Renamed "Independent Directors"A symbolic but important change that emphasizes the need for directors to act independently of management and controlling shareholders.Mandatory Hybrid Shareholder MeetingsFor publicly traded firms with more than 2 trillion won in assets, hybrid shareholder meetings will be mandatory. This will allow shareholders to participate and vote online, increasing accessibility and participation.Increased Proportion of Independent DirectorsThe required proportion of independent directors on the board has been raised from one-quarter to one-third, further strengthening independent oversight of management."Yellow Envelope Bill"This measure, passed alongside the boardroom reforms, secures bargaining rights for subcontracted workers, which could have a significant impact on the labor practices of chaebol.Revamping Public Broadcaster GovernanceThe reforms also include measures to revamp the governance of public broadcasters, which could reduce the influence of chaebol on the media.UnitedHealth forms new ‘public responsibility' board committeeThe committee will oversee areas where UnitedHealth has struggled or faced public scrutiny: underwriting and forecasting, regulatory relationships, reputational matters, and M&A.Michele Hooper, who's served on UnitedHealth's board since 2007, will step down as lead independent director to chair the committee. Hooper, who will remain a director, will be replaced as lead independent director by F. William McNabb, the former CEO of investing firm the Vanguard Group who has served on UnitedHealth's board since 2018.The U.S. EV fast-charging network is seeing explosive growth—despite Trump's policiesInstallation of fast DC chargers that can get an EV to 80% charged in less than an hour are up more than 25% from 2024—despite the loss of Biden administration initiatives designed to support the growth of the network.Companies with climate targets have more than tripled since 2023The number of companies worldwide with both validated near-term and net-zero science-based climate targets has more than tripled since the end of 2023, from 583 to 1,904, according to the Science-Based Targets initiative (SBTi).A total of 10,949 companies worldwide now either have near-term targets or near-term and net-zero targets, or have committed to set them, according to a report by the Science-Based Targets initiative.Air Canada reaches a deal to end flight attendant strikeThe tentative deal secures Air Canada flight attendants at least 60 minutes of ground pay, for their time before each flight, at a rate of 50 per cent of a flight attendant's hourly rate, with that rate increasing five per cent each year.The airline is also proposing immediate pay increases of 12 per cent for flight attendants with five years or less of service with Air Canada, and eight per cent for those who have worked at the airline longer than that.Kimbal Musk on Elon's Tesla pay package: 'My brother deserves to be paid'

Send us a textDr. Barrett Keene is the Senior Director of Talent Development at Stanford Health Care. He previously served as Director of Talent Development at Intuit, where he led teams that develop leaders in Silicon Valley and across the world. Before Intuit, Barrett worked at Tesla as an executive coach and the Head of Leadership and Talent Development for Tesla's Engineering organizations. In addition to Barrett's work as an internal Leadership and Talent Development leader, Barrett spent four years helping nine Fortune 100 companies develop their leaders and employees with Accenture Strategy and the previous eleven years as an independent leadership development consultant within more than 80 organizations.Before joining Accenture, Barrett completed a PhD at Cornell University focusing on Transformational Leadership and Behavioral Integrity and a Master of Business Management while teaching middle school and high school in Miami and Tampa. Barrett lives with his wife and children in Palo Alto, California.A Quote From This Episode“We've skipped over transactional leadership for too long, but without those foundations, the staircase of leadership falls apart.”Resources Mentioned in This Episode 

This week, the Justice brothers dive deep into Jerome Powell's Jackson Hole speech and what it means for the future of monetary policy. Is the Fed finally ready to cut rates—or is Powell once again too cautious, earning the nickname “Too Late Powell”? Matt and Mark break down Powell's dovish tone, the shift from inflation risk to labor market fragility, and how traders should interpret the Fed's pivot back to flexible inflation targeting. Then, the conversation moves into one of the most important technical developments of the year: multiple-time frame breakouts across the Dow, Russell 2000, and the Equal-Weight S&P. Breadth has returned to the market, strengthening the bull case beyond the mega-caps.  In “Stock It or Drop It,” the guys bring analysis and setups on some of the week's biggest movers: Nvidia, Zoom, Palo Alto, Walmart, Estee Lauder, and more. And in this week's Coaches Corner, they tackle trader lifestyle questions—from how much time you really need to dedicate to trading, to whether copying others' strategies can work, to the eternal debate of luck vs. skill. Insightful, actionable, and always entertaining —don't miss this episode of the Trading Justice Podcast.

Cramer says this cybersecurity stock is a buy. Become a CNBC Investing Club member to go behind the scenes with Jim Cramer and Jeff Marks as they talk candidly about the market's biggest headlines. Signup here: cnbc.com/morningtake CNBC Investing Club Disclaimer

We happen to work with a lot of contractors, but it doesn't really matter what type of business you're in. There are so many business owners that want to scale their product, actually grow the value of their product. They want to go from selling a product or service that's X and offers X at this price, to being able to 2x or 5x it—make it more robust, bigger, or whatever. We talk about these systems all the time. Implementing effective systems to ensure consistent profitability is a critical aspect of not only running a business but also being able to scale a product. Hey, it's Scott Beebe with Business On Purpose. Let's talk about this idea, and I want to give you a real-world example of a client of ours. I'll share his name—got his permission—who was able to 5x his project size. We only asked a couple of key questions, and I want to walk you through that. My buddy Sean Supple, who owns Supple Homes out of Menlo Park and Palo Alto in the Silicon Valley area of California, was laboring away at this wonderful home building company. They were servicing a lot of $2–3 million projects, which, depending on where you live, is a significant project size. But Sean knew he and his team were capable of taking on more unique opportunities, particularly in their market, and they wanted to go after those. Like most contractors, cash flow was always an issue due to the expense of running a business. With 78–82% cost of goods, plus the realities of the Silicon Valley market, it was a challenge. So Sean and his team committed to subdividing their bank accounts—something we talk about all the time. By cutting up their dollars and placing them in separate “homes,” they could see where the money was and also map out their entire process. They created a master process roadmap, even distilled into learning pathways, and committed to RPM communication (Repetition, Predictability, and Meaning). That meant regular agenda-driven, leader-led, one-hour team meetings, departmental meetings, one-on-one check-ins, and executive-level meetings. But what they found themselves needing was a more meaningful marketing plan. So we asked this one key question—the one I want you to write down: Where has 80% of your business come from in the past? We meet so many business owners who want to hire outsourced marketing firms. That's fine, but the reality is they're chasing new pathways when often the answer is in plain sight. Building new channels is like building a building—it takes years of groundwork. Instead, look back and ask: Where has 80% of your business come from in the past? For Sean, the answer was easy: architects. Rather than wasting resources on random efforts, we mapped out a simple, intentional, repetitive, predictable, and meaningful outreach process to a basic list of local architects. Within a few months, Supple Homes began securing larger, more complex projects by nurturing those existing relationships. Sean and his team built financial processes, marketing processes, sales/conversion processes, and operational processes. This gave both his team and prospective clients confidence in their ability to deliver on larger, more challenging projects. The impact of Sean's new commitment to process implementation went far beyond immediate financial gains. By maintaining a solid cash balance—something many contractors struggle with—they no longer had to rely on borrowed money, credit lines, or constant lending. Instead, with subdivided cash and clear processes, they sustained financial stability and gained the confidence to take on larger projects. As a result, Sean and his team successfully transitioned from handling $2–3 million projects to $8–11 million projects. Yes, the market helped, but the real key was their strong financial foundation. Winning projects is one thing; delivering them profitably and on schedule is another. Sean's story illustrates several key points for contractors looking to improve profitability: Regular financial tracking—even if only a few minutes a week—can greatly improve cash flow management. Subdividing bank accounts helps visualize and control finances. Much of cash management is more about psychology than the dollar itself. Control your money rather than letting it control you. Maintaining a healthy cash balance provides confidence and capability to take on larger projects. Cash gives you options. Without it, your options shrink. Improved processes and profitability allow reinvestment in the business, employee incentives, and personal profit—all critical for long-term success. By implementing these systems, you can achieve the kind of growth Sean did. Markets will rise and fall, but preparation and process allow you to handle whatever comes your way. So remember this key question: Where has 80% of your business come from in the past? And what systems do you have to repetitively, predictably, and meaningfully mine that 80%? Because that's where most of your future business will likely come from as well. We can help you map this out. If you'd like a one-time consulting opportunity with us, go to businessonpurpose.com, fill out the contact form, and we'll walk you through options to get kickstarted. And if you want to work with us long term, we'll explain how that works too.

Comment rater son couple à coup sûr. C'est ce qu'Emmanuelle Piquet explique dans son nouveau livre.Emmanuelle est thérapeute depuis plus de 15 ans et elle accompagne au quotidien des personnes en souffrance. Comme elle l'explique, régulièrement, les personnes qui viennent la voir en individuel sont en fait des personnes en difficulté dans leur couple.Dans ce livre, plein d'humour évidemment, Emmanuelle veut vous montrer que les problématiques que rencontrent les couples sont, au final, assez communes dans leurs origines.Dans cet épisode, on parle des cercles vicieux dans lesquels on peut toutes et tous se retrouver, on parle de l'envie de contrôler son partenaire et de ce que cela cache, on parle de notre incapacité à communiquer nos besoins correctement et de ses conséquences, et on aborde les disputes de couple sous un angle nouveau et rafraîchissant.Alors, embarquez avec nous dans ce monde sinueux des relations de couple et de leurs ruptures.Je vous souhaite une très bonne écoute.LIENS UTILES :Comment rater son couple à coup sûr, Emmanuelle Piquet

Palo Alto Networks is bracing investors with its latest earnings, homebuilders are sweetening deals to attract strapped buyers, and footwear brands are rewriting the playbook. Today on Motley Fool Money, analysts Emily Flippen, Sanmeet Deo, and David Meier evaluate how industries and businesses adapt even when the landscape changes. They debate: - Palo Alto's strong fourth quarter report - How the landscape of shoe fashion has changed -Housing headwinds Companies discussed: PANW, FTNT, CROX, ONON, NKE, FL Host: Emily Flippen Guests: Sanmeet Deo, David Meier Producer: Anand Chokkavelu Engineer: Dan Boyd Disclosure: Advertisements are sponsored content and provided for informational purposes only. The Motley Fool and its affiliates (collectively, “TMF”) do not endorse, recommend, or verify the accuracy or completeness of the statements made within advertisements. TMF is not involved in the offer, sale, or solicitation of any securities advertised herein and makes no representations regarding the suitability, or risks associated with any investment opportunity presented. Investors should conduct their own due diligence and consult with legal, tax, and financial advisors before making any investment decisions. TMF assumes no responsibility for any losses or damages arising from this advertisement. We're committed to transparency: All personal opinions in advertisements from Fools are their own. The product advertised in this episode was loaned to TMF and was returned after a test period or the product advertised in this episode was purchased by TMF. Advertiser has paid for the sponsorship of this episode. Learn more about your ad choices. Visit ⁠⁠megaphone.fm/adchoices Learn more about your ad choices. Visit megaphone.fm/adchoices

Carl Quintanilla, Sara Eisen, and David Faber broke down the latest consumer reads out of earnings – as Home Depot kicks off a make-or-break week of retail results. Executives calling out strong momentum… But former Chief Investment Strategist for Bridgewater Rebecca Patterson says demand risks remain, breaking down her playbook for volatility. Plus: one of the street's top retail analysts gave his key stocks to buy – and avoid – in the space… and the CEO of Palo Alto Networks joined the team to discuss new numbers from his company.   Also in focus: Intel gaining as Softbank invests $2 billion and reports grow around a possible government stake – what Commerce Secretary Howard Lutnick told the team about that news, and possible rails M&A.  

Carl Quintanilla, David Faber and Mike Santoli led off the show with developments regarding Intel: Softbank investing $2 billion in the company, as the Trump Administration reportedly weighs taking a 10% stake in the chipmaker. Commerce Secretary Howard Lutnick joined the program and discussed a potential government investment in Intel. Also in focus: Home Depot's quarterly miss, Palo Alto Networks sharesjump on earnings, Nexstar to buy rival TV stations operator Tegna, the "SPAC king," Medtronic and activism, why one particular stock is plummeting 40%. Squawk on the Street Disclaimer

As Scott-Free August rolls on, Kara is joined by guest co-host David Remnick, editor of The New Yorker, and host of The New Yorker Radio Hour. Kara and David discuss Trump's federal takeover of the D.C. police, and look ahead to the "feel-out" meeting with Putin in Alaska this week. Plus, redistricting fights spread across the country, Cuomo pulls some punches on Mamdani (with limited success), and Zuck's Palo Alto compound faces scrutiny. Watch this episode on the ⁠⁠Pivot YouTube channel⁠⁠. Follow us on Instagram and Threads at ⁠⁠@pivotpodcastofficial⁠⁠. Follow us on Bluesky at ⁠⁠@pivotpod.bsky.social⁠⁠ Follow us on TikTok at ⁠⁠@pivotpodcast⁠⁠. Send us your questions by calling us at 855-51-PIVOT, or at ⁠⁠nymag.com/pivot⁠⁠. Learn more about your ad choices. Visit podcastchoices.com/adchoices

Today's show:On an all-new Monday TWiST, Lon joins Jason and Alex to talk about a whole bunch of stories at the intersection of tech, business, and pop culture.First up, is GPT Psychosis real? And if so, what are the warning signs that your loved ones have been ONESHOTTED.Then, why did Jason get so upset at the NY Times piece about Mark Zuckerberg's Palo Alto compound?PLUS we're discussing Trump's export fees on AMD and Nvidia, Jason's pitch for why the president should work more closely with Congress, a new tool in the search for rare-earth minerals, just how many self-driving trucks are on Chinese roads today, and much much more!Timestamps:(0:00) INTRO, Why Jason hated the NYT story about Mark Zuckerberg's compound.(09:54) Vouched - Trust for agents that's built for builders like you. Check it out at http://vouched.id/twist(11:14) Show continues…(19:54) Coda - Empower your startup with Coda's Team plan for free—get 6 months at https://www.Coda.io/twist(21:01) Show continues…(27:25) GPT Psychosis: Is it real and how widespread is it?(29:13) Vanta - Get $1000 off your SOC 2 at https://www.vanta.com/twist(30:16) Show continues…(45:45) What it means to get “One-Shotted”: is Sam Altman doing this on purpose?(53:56) Jason says working multiple jobs at once is STEALING… is that fair?(01:04:53) Are Trump's Chinese export fees for AMD and Nvidia a justified licensing process? Or a shakedown?(01:09:22) Jason's pitch for working closer with Congress, and why Alex has concerns about clarity(01:12:02) PolyMarket: Will tariffs generate >$250b in 2025?Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcpFollow Lon:X: https://x.com/lonsFollow Alex:X: https://x.com/alexLinkedIn: ⁠https://www.linkedin.com/in/alexwilhelmFollow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanisThank you to our partners:(09:54) Vouched - Trust for agents that's built for builders like you. Check it out at http://vouched.id/twist(19:54) Coda - Empower your startup with Coda's Team plan for free—get 6 months at https://www.Coda.io/twist(29:13) Vanta - Get $1000 off your SOC 2 at https://www.vanta.com/twistGreat TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarlandCheck out Jason's suite of newsletters: https://substack.com/@calacanisFollow TWiST:Twitter: https://twitter.com/TWiStartupsYouTube: https://www.youtube.com/thisweekinInstagram: https://www.instagram.com/thisweekinstartupsTikTok: https://www.tiktok.com/@thisweekinstartupsSubstack: https://twistartups.substack.comSubscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916

Erlang OTP SSH Exploits A recently patched and easily exploited vulnerability in Erlang/OTP SSH is being exploited. Palo Alto collected some of the details about this exploit activity that they observed. https://unit42.paloaltonetworks.com/erlang-otp-cve-2025-32433/ WinRAR Exploited WinRAR vulnerabilities are actively being exploited by a number of threat actors. The vulnerability allows for the creation of arbitrary files as the archive is extracted. https://thehackernews.com/2025/08/winrar-zero-day-under-active.html Citrix Netscaler Exploit Updates The Dutch Center for Cyber Security is updating its guidance on recent Citrix Netscaler attacks. Note that the attacks started before a patch became available, and attackers are actively hiding their tracks to make it more difficult to detect a compromise. https://www.ncsc.nl/actueel/nieuws/2025/07/22/casus-citrix-kwetsbaarheid https://www.bleepingcomputer.com/news/security/netherlands-citrix-netscaler-flaw-cve-2025-6543-exploited-to-breach-orgs/ OpenSSH Post Quantum Encryption Starting in version 10.1, OpenSSH will warn users if they are using quantum-unsafe algorithms https://www.openssh.com/pq.html