POPULARITY
Contributor: Travis Barlock, MD Educational Pearls: What is Portal Vein Thrombosis? The formation of a blood clot within the portal vein, which carries blood from the gastrointestinal tract, pancreas, and spleen to the liver Not only can this cause problems downstream in the liver, but the backup of venous blood can cause ischemia in the bowels How does it present? Similar to acute mesenteric ischemia: Sudden onset of abdominal pain, nausea, vomiting, and fever How is it diagnosed? Abdominal CT or MRI with contrast What causes it? Cirrhosis Coagulopathy (Factor V Leiden mutation, Prothrombin gene mutation, Antiphospholipid syndrome, Protein C, protein S, antithrombin III deficiency, etc.) Oral Contraceptive Pills (OCPs) Cancer such as hepatocellular carcinoma How is it treated? Aggressive fluid resuscitation Antibiotics. Be sure to cover enteric gram-negative bacteria and anaerobes Heparin, same dosing as a bolus for a DVT Endovascular treatment, such as a thrombectomy with IR Surgical evaluation if there has been tissue death in the mesentery References Hilscher, M. B., Wysokinski, W. E., Andrews, J. C., Simonetto, D. A., Law, R. J., & Kamath, P. S. (2024). Portal Vein Thrombosis in the Setting of Cirrhosis: Evaluation and Management Strategies. Gastroenterology, 167(4), 664–672. https://doi.org/10.1053/j.gastro.2024.05.017 Intagliata, N. M., Caldwell, S. H., & Tripodi, A. (2019). Diagnosis, Development, and Treatment of Portal Vein Thrombosis in Patients With and Without Cirrhosis. Gastroenterology, 156(6), 1582–1599.e1. https://doi.org/10.1053/j.gastro.2019.01.265 Ju, C., Li, X., Gadani, S., Kapoor, B., & Partovi, S. (2022). Portal Vein Thrombosis: Diagnosis and Endovascular Management. Pfortaderthrombose: Diagnose und endovaskuläres Management. RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 194(2), 169–180. https://doi.org/10.1055/a-1642-0990 Summarized by Jeffrey Olson MS3 | Edited by Jorge Chalit, OMS3 Donate: https://emergencymedicalminute.org/donate/
It might be time to rethink your liver biopsy technique. Transfemoral transcaval core-needle liver biopsy has demonstrated key advantages over the transjugular approach and has become increasingly popular in recent years. Interventional radiologists Dr. Jacob Cynamon and Dr. Kapil Wattamwar join host Dr. Sabeen Dhand to discuss the inception and advantages of their novel approach. --- This podcast is supported by: Reflow Medical https://www.reflowmedical.com/ --- SYNPOSIS The doctors start with how they began using the transfemoral transcaval approach, along with the literature they published following adoption of this novel technique shortly thereafter. Dr. Cynamon and Dr. Wattamwar then go on to discuss the technique in detail, providing a thorough step-by-step and pausing to mention key considerations. The episode concludes with the doctors emphasizing the safety and efficacy of the transfemoral transcaval approach, citing specific findings and sharing exemplary cases. --- TIMESTAMPS 00:00 - Introduction 05:47 - Percutaneous vs. Transvenous Biopsies 08:56 - Evolution of Transfemoral Biopsies 12:41 - Comparing Transjugular and Transfemoral Approaches 24:52 - Pre-Procedural Imaging and Sheath Selection 29:23 - Complications and Case Studies 35:46 - Transcaval Biopsy Technique 45:00 - Conclusion --- RESOURCES Cynamon, 2016. Transfemoral Transcaval Core-Needle Liver Biopsy: An Alternative to Transjugular Liver Biopsy: https://pubmed.ncbi.nlm.nih.gov/26723528/ Wattamar, 2020. Transjugular versus Transfemoral Transcaval Liver Biopsy: A Single-Center Experience in 500 Cases: https://pubmed.ncbi.nlm.nih.gov/32798119/ Wattamar, 2022. The Use of the Transfemoral Transcaval Liver Biopsy Technique for Biopsies of Hepatic Masses: https://pubmed.ncbi.nlm.nih.gov/36182256/ Wattamar, 2022. Transcaval Creation of a Portal Vein Target for Transjugular Intrahepatic Portosystemic Shunt in a Patient with Portal Vein Thrombosis: https://pubmed.ncbi.nlm.nih.gov/34448032/
Get caught up on prostate artery embolization (PAE) best practices and learn the ins-and-outs of building a PAE program in 2024. Dr. Jason Hoffmann covers this and more, with host Dr. Michael Barraza. Dr. Hoffmann is an interventional radiologist and educator at NYU Langone Health. --- CHECK OUT OUR SPONSOR Merit Biopsy Solutions https://www.merit.com/solutions/biopsy-solutions/ --- SYNPOSIS The doctors delve into strategies for developing expertise within a practice, coordinating with urologists, and effectively managing patient expectations. Dr. Hoffmann shares insights on leveraging different imaging techniques, equipment choices, and best practices for ensuring post-procedure patient satisfaction. The discussion also touches on the evolution of PAE guidelines, insurance challenges, and the importance of longitudinal care in interventional radiology. --- TIMESTAMPS 00:00 - Introduction 04:12 - Building a BPH Program and PAE Practice 06:28 - Referrals and Relationship with Urology 15:27 - Patient Workup and Setting Expectations 27:10 - SwiftNinja Study: Initial Impressions and Findings 31:43 - Patient Management and Post-Procedure Care 35:37 - Building a Successful PAE Practice 42:19 - Conclusion --- RESOURCES BackTable VI Podcast Episode #445 - Inside the IR Suite: A Clinician's Own Battle with Portal Vein Thrombosis with Dr. Jason Hoffmann: https://www.backtable.com/shows/vi/podcasts/445/inside-the-ir-suite-a-clinicians-own-battle-with-portal-vein-thrombosis AUA Guidelines on Benign Prostatic Hyperplasia (Updated 2023): https://www.auanet.org/guidelines-and-quality/guidelines/benign-prostatic-hyperplasia-(bph)-guideline Use of a steerable microcatheter during superselective angiography: impact on radiation exposure and procedural efficiency: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966367/
Host: Peter Buch, MD, FACG, AGAF, FACP Guest: Shilpa Junna, MD Symptoms of portal vein thrombosis (PVT) are primarily driven by the extent of the obstruction that the PVT is causing, and some of it's also driven by how quickly the thrombosis has developed. There's also some cases where symptoms can be nonspecific. So the role of a multidisciplinary team in helping to address this condition is very important because every case is unique. This collaboration can help provide the best care to our patients case by case. Dive in with Dr. Peter Buch and Dr. Shilpa Junna, Transplant Hepatologist and Assistant Professor at the Cleveland Clinic, to learn more.
Host: Peter Buch, MD, FACG, AGAF, FACP Guest: Maurizio Bonacini, MD Patients with cirrhosis of the liver are typically more susceptible to portal vein thrombosis (PVT). So how can we provide the best care to our PVT patients? To find out, Dr. Peter Buch is joined by Dr. Maurizio Bonacini, CEO of Mission Gastroenterology and Hepatology and Associate Clinical Professor of Medicine at the University of California, San Francisco.
In this episode of EASL Studio the experts discuss a non-cirrhotic portal vein thrombosis (PVT):What is PVT in the absence of cirrhosis,The role of interventional radiology in the management of portal cavernoma, andAn update from the VALDIG portal Vein Thrombosis meetingFacultyProf. Pierre-Emmanuel Rautou (Moderator)Prof. Juan-Carlos Garcia-Pagan (Faculty)Dr Aurélie Plessier (Faculty)All EASL Studio Podcasts are available on EASL Campus.
Lurie Children's is one of the only pediatric hospitals in the world home to experts in the surgical treatment and care for children with a rare disorder in which a clot forms blocking the main portal vein going into the liver. This condition is known as portal vein thrombosis, the cause of which in many cases is never determined. At Lurie Children's, two pediatric liver experts are able to help many children with this condition avoid a liver transplant, even when their families have previously been told that is the only treatment. Today we talk with those physician-surgeons, Drs. Riccardo Superina and Caroline Lemoine.
In this part 2 of our 2 part series on Liver Emergencies we clear up the confusing balance between thrombosis and bleeding in liver patients, the elusive diagnosis of portal vein thrombosis, spontaneous bacterial peritonitis diagnosis and treatment and some tips and tricks on paracentesis with Walter Himmel and Brain Steinhart.... The post Ep 149 Liver Emergencies: Thrombosis and Bleeding, Portal Vein Thrombosis, SBP, Paracentesis Tips and Tricks appeared first on Emergency Medicine Cases.
Hepatologists Bilal Hameed, MD, UCSF and Norah Terrault, MD, UCSF. Series: "UCSF Transplant Update" [Health and Medicine] [Education] [Professional Medical Education] [Show ID: 33247]
Hepatologists Bilal Hameed, MD, UCSF and Norah Terrault, MD, UCSF. Series: "UCSF Transplant Update" [Health and Medicine] [Education] [Professional Medical Education] [Show ID: 33247]
Audible Article by Thomas D. Boyer, M.D., and Shahid Habib, M.D.
Audible Article by Thomas D. Boyer, M.D., and Shahid Habib, M.D.
Upper gastrointestinal bleeding episodes from variceal structures are severe complications in patients with portal hypertension. Endoscopic sclerotherapy and variceal ligation are the treatment options preferred for upper variceal bleeding owing to extrahepatic portal hypertension due to portal vein thrombosis (PVT). Recurrent duodenal variceal bleeding in non-cirrhotic patients with diffuse porto-splenic vein thrombosis and subsequent portal cavernous transformation represent a clinical challenge if classic shunt surgery is not possible or suitable. In this study, we represent a case of recurrent bleeding of duodenal varices in a non-cirrhotic patient with cavernous transformation of the portal vein that was successfully treated with a collateral caval shunt operation.
Dr. Susana Seijo discusses her manuscript, "Efficacy and Safety of Anticoagulation on Patients With Cirrhosis and Portal Vein Thrombosis."
Dr. Susana Seijo discusses her manuscript, "Efficacy and Safety of Anticoagulation on Patients With Cirrhosis and Portal Vein Thrombosis."
Treatment of Ascites, Portal Vein Thrombosis and Hepatic Encephalopathy in Patients with Cirrhosis of the Liver Background: Ascites, portal vein thrombosis and hepatic encephalopathy are important complications of cirrhosis of the liver. Guidelines for the treatment of ascites have recently been published. Method: This manuscript summarizes up-to-date recommendations on the basis of the DGVS S3 guideline and of other guidelines as well as of the authors' experience. Results and Conclusions: TIPS (transjugular intrahepatic porto-systemic shunt) is the preferred treatment for refractory or recidivant ascites unless there are contraindications. The therapy of hepatorenal syndrome type 1 with albumin and the vasoconstrictor Terlipressin has been proven effective. Treatment of portal vein thrombosis comprises a strategy of anticoagulation, TIPS and liver transplantation. The most important therapeutic strategy for hepatic encephalopathy is the search for as well as the treatment of trigger events. Rifaximin is being increasingly used for the treatment and prophylaxis of hepatic encephalopathy.