Podcasts about as charlotte

This weeks episode is an interview I did with Charlotte Balbier on Instagram a few weeks ago on " Thinking Bigger" Charlotte had a 7 figure Bridal Business which she sold and took early retirement. Charlotte is now a mentor who helps businesses scale.  As Charlotte explains, thinking bigger requires your Mindset to expand with allowing those bigger thoughts and dreams to flow.  You can find Charlotte on Instagram by clicking HERE Have you signed up to receive my Free ebook? 5 MISTAKES YOU ARE MAKING TO SLOW YOUR METABOLISM WITHOUT KNOWING"  TO SIGN UP TO RECEIVE MY EBOOK CLICK HERE 

You return to work after maternity leave, get settled into the inevitable juggling act, and then you’re faced with the prospect of redundancy. You decide it’s the perfect time to take a career break to raise your child, and then, boom! Before you know it, the years have crept by, and you’re sat there with a big fat case of imposter syndrome, wondering if your skills are even relevant in today’s working world (they absolutely are, FYI). This is precisely the situation our guest on this week’s podcast found herself in. But, for Charlotte English of Funky Makers, she grabbed this ‘growth opportunity’ by the horns and got stuck into something that lights her up: craft. Knitting, crochet, stitch art, papercraft, mending, and upcycling – you name it, Charlotte does it. And, what’s more, she loves sharing what she does with others. So much so, she’s launching online workshops in January (go, Charlotte!

The simple idea for today's episode is to consciously stay open to learning, even if we've been around horses our entire lives. Charlotte points out that being open allows us to be more available for our horses, making their lives more fulfilling. And that's what we all want right? For our animals to feel fulfilled. Charlotte Chanler can talk horse. Seriously! She is an animal communicator and medium who spends a lot of time talking to horses. She grew up in the traditional competition circuit from the time that she was a little girl, sometimes witnessing the power of alternative healing techniques. As Charlotte grew, she honed her intuition and began to connect to the animals around her more deeply. She now brings a gentle, holistic approach to helping animals and their people connect. Charlotte is a co-founder of Hearthorse, an online community and subscription box for people whose hearts belong to their horses. She focuses on infusing a positive approach toward training and interacting with horses in everything she does. She's a voice for the rescue community, and encourages everyone to stay open, continue to learn, and continue to connect with their horse on a deeper, more understanding level. Charlotte is joining me from her home in Los Angeles, California (amazingly just 2 miles up the road from me!) For detailed show notes, including a summary of our conversation, live video recording, and links to everything important, visit: http://ForAnimalsForEarth.com/podcast/14

This week’s episode includes author Charlotte Andersson and Associate Editor Naveed Sattar as they discuss familial clustering of aortic size, aneurysms, and dissections in the community. TRANSCRIPT: Dr Carolyn Lam: Welcome to Circulation on the Run, your weekly podcast, summary, and backstage pass to the journal and its editors. I'm Dr Carolyn Lam, Associate Editor from the National Heart Center and Duke national University of Singapore. Dr Greg Hundley: And I'm Greg Hundley, director of the Pauley Heart Center at VCU health in Richmond, Virginia. Well, Carolyn, our feature this week has to do with aortic size, aneurysms, and predilection to dissection. But before we get to that, how about if we grab a cup of coffee and go through some of the other articles in the issue? Dr Carolyn Lam: I got my coffee, Greg, and you know what? I'm going to start with quiz for you. Dr Greg Hundley: All right. Dr Carolyn Lam:  True or false, in the setting of obesity and/or diabetes, cardiac substrate metabolism shifts towards increased fatty acid oxidation, while lipid accumulates in the heart? True or false? Of course, you're right. Oh, but there's a part two. Can you guess, by increasing fatty acid oxidation, will we induce or prevent obesity-induced lipotoxic cardiomyopathy? Dr Greg Hundley: I'm going to say, because you asked it in the way you asked it, prevent. Dr Carolyn Lam: Wow. All right. Well, the truth is we didn't really know before today's paper. The specific link between cardiac metabolism and lipotoxic cardiomyopathy was elusive and there was no specific therapy available for this condition. And these authors, Dr Rong Tian from University of Washington and colleagues, hypothesized that cardiac pathology-associated obesity would be attributable to the imbalance of fatty acid supply and oxidation. So using a diet-induced obesity model in the current study, they demonstrated that enhancing fatty acid oxidation through deletion of acetyl-CoA carboxylase 2, was sufficient to prevent obesity-induced cardiomyopathy. So, increasing cardiac fatty acid oxidation alone does not cause cardiac dysfunction, but instead protects against cardiomyopathy in chronically obese mice. The cardiac-protective effect of increasing fatty acid oxidation and obese mice is through maintenance of Parkin-mediated mitophagy, and thus preventing mitochondrial dysfunction. These findings indicate that impaired mitophagy contributes to mitochondrial dysfunction in obese mice, and that targeting the Parkin-dependent pathway is a viable therapeutic intervention for obesity-induced cardiomyopathy. Dr Greg Hundley: Very nice. Carolyn. Dr Carolyn Lam: I'm going to be greedy and go on to my next paper. So Greg, do you think cardiac regeneration is possible? Dr Greg Hundley: Well, Carolyn, I would have said, several years ago, no, but that trip that we took to China with Joe Hill and Hesham Sadek, our Associate Editor and our Chief Editor, convinced me otherwise. So I'm going to definitely answer yes on this one. Dr Carolyn Lam: Oh, Greg, you're just too smart. And speaking of China, this next paper is from there, from co-corresponding authors, Dr Nie and Hu, from Fuwai Hospital National Center for Cardiovascular Disease and Chinese Academy of Medical Sciences and Peking Union Medical College. So, using seven genetic mouse lines, they identify that Oncostatin M is the top upregulated cytokine during neonatal heart regeneration. Oncostatin M is a pleiotropic secretory protein that belongs to the interleukin 6 family, and associates with the pathological process of dilated cardiomyopathy. And these authors found that macrophages promote heart regeneration by secreting Oncostatin M, which promotes cardiomyocyte proliferation via a co-receptor, gp130. Employing RNA-seq and functional screening, they further found that Src-mediated gp130 triggered cardiomyocyte proliferation by activating the downstream signaling pathway involving Yap, with Y357 phosphorylation independent of the Hippo pathway. So the last thing that they did was show that gene therapy with adenovirus-associated virus and coding this activated gp130 improved heart regeneration and pumping function, thus serving as a potential therapeutic target. An amazing paper. Dr Greg Hundley: Very nice, Carolyn. What a great summary and so much detail. Well, Carolyn, I'm going to turn our attention to catecholaminergic polymorphic ventricular tachycardia. And this article comes to us from Dr Jason Roberts, from the Western University. Carolyn, genetic variants in calsequestrin 2 can cause an autosomal recessive form of catecholaminergic polymorphic ventricular tachycardia, though isolated reports have identified arrhythmogenic phenotypes among heterozygotes. So in this study, a total of 112 individuals, including 36 catecholaminergic polymorphic ventricular tachycardia probands, 24 were homozygotes for compound heterozygotes, and 12 were pure heterozygotes, against 76 family members possessing at least one presumed pathogenic calsequestrin 2 variant. These were all identified. Dr Carolyn Lam: Wow, a very precious cohort. So what did they find, Greg? Dr Greg Hundley: This international multicenter study of calsequestrin 2 catecholaminergic polymorphic ventricular tachycardia really redefined its heritability and confirmed that pathogenic heterozygous calsequestrin 2 variants may manifest with a catecholaminergic polymorphic ventricular tachycardia phenotype, indicating a need to clinically screen these individuals. Among individuals heterozygous for a pathogenic calsequestrin 2 rare variant, medical therapy and exercise restriction are likely not necessary in the absence of the catecholaminergic polymorphic ventricular tachycardia phenotype. Though, you have to be certain over time, an intermittent clinical screening to ensure they remain phenotype-negative should be obtained. Dr Carolyn Lam: Wow, Greg, clinically important study there. Well, I'm going to go back to the basic science world and talk about calcineurin. Now, calcineurin has long been implicated in the induction of pathological cardiac remodeling but has not been therapeutically targetable for the prevention of heart failure because of its pleiotropy and our lack of understanding of its specific protein-protein interactions and compartmentation within the cardiomyocyte. Dr Greg Hundley: Okay. Carolyn, do you want me to give background on calcineurin? Dr Carolyn Lam: No, Greg, you're off the hook. I'm going to give you some background on calcineurin. So, calcineurin is the calcium-calmodulin-dependent phosphatase that exists as a heterodimer, consisting of a catalytic subunit and a regulatory subunit. Now, of the three catalytic subunit isoforms, alpha, beta, gamma, it's the beta isoform that appears to be the most important for the development of cardiac hypertrophy. Binding of calcium to the calcineurin regulatory subunit enables binding of the calcium-calmodulin complex, thereby releasing auto-inhibition and freeing the enzyme to dephosphorylate downstream substrates. That's the background. Now, in today's issue, we have this great paper from co-corresponding authors, Dr Kapiloff from Stanford University, and Dr Nikolaev from University Medical Center Hamburg. And, with their colleagues, they described the discovery of a calcineurin catalytic subunit beta binding protein Cdc42-interacting proteins 4, and I'm going to call that CIP4, which functions as a scaffold to sequester the pool of calcineurin near the sarcolemma of cardiomyocytes, where it regulates pro-hypertrophic signaling. These findings have really important implications for understanding how cardiac calcineurin is selectively activated by stress signals, as opposed to the pleiotropic second messenger, calcium, that really floods the cardiomyocytes during each contractile cycle. Furthermore, the data provide proof of concept for an innovative therapeutic approach, whereby CIP4-anchoring activity is selectively inhibited to block the action of a small pathogenic pool of calcineurin as a means of treating heart failure. How about that? This is really discussed in an elegant editorial by doctors, Woulfe, Travers, and McKinsey. Dr Greg Hundley: Very interesting, Carolyn. Sounds like another possibility for treating and managing heart failure. Well, let me share with you some of the other findings in our mailbag this week. First, I've got, from Professor Lang Li and Stephen Wiviott, they swap research correspondence regarding the prior publication entitled, Effect of Dapagliflozin on Atrial Fibrillation in Patients with Type 2 Diabetes Mellitus, Insights from the DECLARE-TIMI 58 Trial. And then Professor Laszlo Littmann has a nice ECG challenge for us related to a high-risk ECG that exposed some downstream worrisome vital signs. Dr Carolyn Lam: In addition, there's a perspective piece by Dr Nambi discussing the fact that a zero-calcium score is desirable, but isn't enough to defer therapy, given that up to one-third of events will occur in this group. There's also an In Depth paper by Dr Borlaug, entitled, “Altered Hemodynamics and End Organ Damage in Heart Failure, The Impact on the Lung and Kidney,” and oh boy, this one is so beautifully illustrated. Just a must read for the understanding of the hemodynamics in the lung and kidney and heart failure. Next is a research letter by Dr Loeys on enrichment of rare variants in the Loeys-Dietz syndrome genes in spontaneous coronary artery dissection, and not in severe fibromuscular dysplasia. And finally, another research letter by Dr Arora on racial differences in serial NT-proBNP levels in heart failure management with insights from the GUIDE-IT Trial. What a rich issue, but let's move on to our future discussion, shall we? Dr Greg Hundley: You bet, Carolyn. Well, listeners, we're now getting to our feature discussion and it's very interesting this week where we're going to evaluate aortic aneurysms. And we have with us one of the lead authors of this paper, Dr Charlotte Andersson from Boston Medical Center, and our own Associate Editor, Naveed Sattar from Glasgow, Scotland. Charlotte, welcome to our feature discussion. Could you tell us a little bit about the background and the hypothesis that you put forward with this study? Dr Charlotte Andersson: The background for this study was based on clinical work and what we observed in clinic. We had a few patients where we had been stricken by the fact that they came in with an acute aortic syndrome and they had a first-degree relative themself with the condition, but they did not look syndromic at all. And we started to wonder, what is the actual risk in the community, in people without obvious syndromic features of suffering from an aortic event itself. And although there are quite a few studies out there that have, to some degree, focused on the familial clustering of aortopathies, there is not a lot of information based on communities and whole entire populations. So we wanted to, frankly, estimate what is the incidence rates of aortic dissections and aortic aneurism in the community if you have a first-degree relative that has suffered from the disease themselves. Dr Greg Hundley: How you organize your study and what was your population and what was your design? Dr Charlotte Andersson: This study was actually based on two independent samples. First, we used the Framingham Heart study population that is very densely phenotypes over many years of spanning three generations of participants, where we looked at people who had at least one parent who had an aortic size in the upper quartile index to body-surface area and adjusted for age and sex. And we saw what's the risk of you, as a child, having an aortic size in the same upper quartile. And second, we looked in the general Danish population, the Danish healthcare system is, as you probably know, governmental funded and we have very good registries of all hospitalizations, all outpatient visits, and so we were able to link more hard clinical events in people with and without a first-degree relative. What we did was we started time when people had an aortic dissection, we identified all the first-degree relatives in these people, and we matched them with up to 10 sex and age match controls from the general population without a first-degree relative with the disease. Dr Greg Hundley: What did you find? Dr Charlotte Andersson: We found that in the Framingham sample, if you had at least one parent who belongs into the upper quartile of aortic size, you had an odds ratio of two to three, adjusted for various clinical risk factors, such as hypertension and smoking yourself. And in Danish population, we found that if you had a first-degree relative with an aortopathy, the hazard rates for you developing the disease yourself was almost a tenfold-increase compared to age and sex match controls. And importantly, seemed like hazard ratios use were, more or less, unchanged when we start adjusting various known risk factors, such as bicuspid aortic valve, Marfan syndrome, and Ehlers-Danlos syndrome, normally those kinds of things. And we also found that the younger your proband were at the time of an acute event, the higher was your relative risk yourself. So among people who were below the age of 50 when they suffered an event, the hazard ratios were up to a 50-fold increase. Dr Greg Hundley: Very nice. Naveed, what attracted you to this article as it was coming through the editorial process? And then second, how do we take the information that Charlotte's just conveyed and will be published here today, how do we take this in the context of what we already know about aortic aneurysms? Dr Naveed Sattar: I think it's a beautiful study, so well done, Charlotte. I think it's a beautiful fusion. As Charlotte said, an in-depth cohort study, which has got very well-measured parameters of systematic points and a fantastic population-based data set from Denmark, which Sweden shares and Scotland shares and relatively small countries like us share. So small countries like Denmark punch above their weight in these kinds of studies, which is fantastic. But there's a rich seam of research that comes from these, and this is one of them. So I think that fusion of two data sets with different strengths and limitations combined giving off same signals is good. I think, as Charlotte said, this is the first major population study to look at this question. So there's been people around the world who have got this sense that the aortic aneurism may well be familial, this provides, probably, some of the best data to suggest, yes, it definitely is. Now the questions going forward is, okay, at what point do you screen everybody's got a family history with a proband, or do you screen those who've got a family history of younger probands? And I think what Charlotte and the team and other people around the world thar are going to look at this say, "Okay, we now think, in addition to screening, for example, in the UK and the US we probably screen just men above 65, where most of the disease is, do we also then implement screening in younger people with family histories? And who do we screen, and when and how? And do we need to develop some kind of risk score?" And then when we do that screening, what do we do about it? Is going to be the questions and I'm sure Charlotte and her colleagues have thought about these things and it'd be interesting to see what her view is on those things. But I think it was a beautiful study in every sense. Dr Greg Hundley: So Charlotte, he's really set you up nicely, what study do we need to perform next in this area? What are you and your group thinking about? Dr Charlotte Andersson: Yeah, I think there are two implications of this study. First, clinical, as Naveed says. They already had a sense that aortic diseases were heritable, and I think these data definitely support that we should probably screen first-degree relatives. And I think, at some extent, this is what the guidelines already encourage us to do. So I'm not sure it would be feasible to randomize people or do a clinical trial where we screen some but not others. I'm not sure that would be ethical. I think the evidence is too strong for familial clustering and that we should probably screen these people. But I think also, our estimates, they are so strong that I suspect that there are likely more genetic variants associated with non-syndromic aortopathies that we are not aware of just yet. So I think the next step would be to try to disentangle the genetics a little bit more. I have seen some preliminary analysis based on the UK Biobank, for instance, and I think there are more genetic variants to come up with also, more common genetic variants, at least, that we are not aware of just yet. So that would be the next step as I see it. Dr Naveed Sattar: And that might particularity in younger probands. Dr Charlotte Andersson: Right. Dr Naveed Sattar: Those with the younger probands, because it looks like, as you said, the hazard ratio, the risks, are so high, it could also potentially be monogenic, but anyway. Dr Charlotte Andersson: I agree. Dr Greg Hundley: Well, Charlotte, Naveed, we really appreciate your time and taking this opportunity to discuss these really interesting findings and helping us understand that, truly, there may be a familial component to understanding this disease process, particularly in patients with aortic aneurysms that may go on to develop aortic dissections. Well listeners, we hope you have a great week and on behalf of Carolyn and myself, catch you on The Run next week. This program is copyright, the American Heart Association, 2020.  

Charlotte from Vengerberg Glamarye returns to join Alyssa from GoodMorhen to discuss Henry Cavill’s favorite short story from Andrzej Sapkowski’s Sword of Destiny, “A Shard of Ice.” Very important bits include: the deep-rooted emotions and insecurities in Geralt and Yennefer’s relationship, adapting The Snow Queen, and the importance of communication in traditional and untraditional relationships. As Charlotte words it: “This chapter is about everyone's facades, the weight of those masks, and the toll it takes on their relationships.” Receive 10% off every purchase at glamarye.com with code: HANZA. The full episode transcript, show notes, and access to our social platforms are available at breakfastinbeauclair.com.  

Gamescom has come and gone and now the industry is turning its head towards the busiest season of the year. An onslaught of games is about to be unleashed on consumers, but on this week's episode of Podtoid, the crew would rather focus on terrible Rodney Dangerfield impressions. As Charlotte introduces us to a new board game, Dan discovers new planets in No Man's Sky, and Chris discusses the Call of Duty beta. All that, plus seagulls are stealing weed, on Podtoid Episode 413.

Over 1 billion people globally experience disability: I in 7 people. So, the question of how we ensure that transport is accessibility and inclusive around the world is vital to explore. This podcast features an interview with Charlotte V. McClain-Nhlapo – Global Disability Advisor at the World Bank Group. Charlotte's TED Talk has received over 10,000 views.The discussion explores what exclusion looks like in the context of transport for people with disabilities and what sort of challenges are out there. As Charlotte leads the Global Disability agenda at the World Bank, she explains what the World Bank doing to ensure that the transport projects it supports capture the demands and needs of disabled people; and gives a view as to what the World Bank worries about when programming its road transport projects.Technology and innovation are changing the complexion of transport for everyone, the discussion explores how advances in technology can help people with disabilities to travel. Charlotte explains how well she thinks that people with hidden disabilities are supported in developed and developing countries.The Department for International Development and the Department for Transport in the UK are organising a session on disability inclusive road transport at the World Road Congress in Abu Dhabi in October this year, Charlotte explains what messages she hopes this session can deliver.Charlotte said in the interview: ‘Diversity is part of our human experience and it’s also about understanding that the onset of disability happens at many stages of our lives: people are born with disabilities, people acquire disabilities later in life, and then there is disability that comes with the onset of ageing. So it’s a part of our life span and for us not to plan for that seems very limiting from a planning point of view’.

Over 1 billion people globally experience disability: I in 7 people. So, the question of how we ensure that transport is accessibility and inclusive around the world is vital to explore. This podcast features an interview with Charlotte V. McClain-Nhlapo – Global Disability Advisor at the World Bank Group. Charlotte's TED Talk has received over 10,000 views.The discussion explores what exclusion looks like in the context of transport for people with disabilities and what sort of challenges are out there. As Charlotte leads the Global Disability agenda at the World Bank, she explains what the World Bank doing to ensure that the transport projects it supports capture the demands and needs of disabled people; and gives a view as to what the World Bank worries about when programming its road transport projects.Technology and innovation are changing the complexion of transport for everyone, the discussion explores how advances in technology can help people with disabilities to travel. Charlotte explains how well she thinks that people with hidden disabilities are supported in developed and developing countries.The Department for International Development and the Department for Transport in the UK are organising a session on disability inclusive road transport at the World Road Congress in Abu Dhabi in October this year, Charlotte explains what messages she hopes this session can deliver.Charlotte said in the interview: ‘Diversity is part of our human experience and it’s also about understanding that the onset of disability happens at many stages of our lives: people are born with disabilities, people acquire disabilities later in life, and then there is disability that comes with the onset of ageing. So it’s a part of our life span and for us not to plan for that seems very limiting from a planning point of view’.

Over 1 billion people globally experience disability: I in 7 people. So, the question of how we ensure that transport is accessibility and inclusive around the world is vital to explore. This podcast features an interview with Charlotte V. McClain-Nhlapo – Global Disability Advisor at the World Bank Group. Charlotte's TED Talk has received over 10,000 views. The discussion explores what exclusion looks like in the context of transport for people with disabilities and what sort of challenges are out there. As Charlotte leads the Global Disability agenda at the World Bank, she explains what the World Bank doing to ensure that the transport projects it supports capture the demands and needs of disabled people; and gives a view as to what the World Bank worries about when programming its road transport projects. Technology and innovation are changing the complexion of transport for everyone, the discussion explores how advances in technology can help people with disabilities to travel. Charlotte explains how well she thinks that people with hidden disabilities are supported in developed and developing countries. The Department for International Development and the Department for Transport in the UK are organising a session on disability inclusive road transport at the World Road Congress in Abu Dhabi in October this year, Charlotte explains what messages she hopes this session can deliver. Charlotte said in the interview: ‘Diversity is part of our human experience and it’s also about understanding that the onset of disability happens at many stages of our lives: people are born with disabilities, people acquire disabilities later in life, and then there is disability that comes with the onset of ageing. So it’s a part of our life span and for us not to plan for that seems very limiting from a planning point of view’.

As Charlotte grows and the roads get more crowded, a lot of attention is being paid to how we'll get around. One of the most talked about projects, is bike and pedestrian paths that connect neighborhoods to work, shopping, and entertainment. What does the City have planned to create safe, convenient connectivity -- without cars? Vivian Coleman is Charlotte's Transportation Planning Program Manager, and she's our guest on this episode of Charlotte Real Estate Talk.

As Charlotte announces her engagement, the team debate eloping and whether big weddings are worth it. All things relationships are up for discussion, including what not to do on a first date, their partner's annoying habits and how to manage money as a couple. Plus, they share the books and TV shows currently on their radar, and their go-to brands for summer dressing. Topics Discussed:Should You Think About Eloping? – https://sheerluxe.com/2018/04/18/should-you-think-about-eloping How To Talk Money With Your Partner Without It Getting Awkward – https://sheerluxe.com/2018/04/24/how-talk-money-your-partner-without-it-getting-awkward 7 Surprising Dating Deal-Breakers – https://sheerluxe.com/2018/04/23/7-surprising-dating-deal-breakersThe Inspiring True Story Set To Be This Summer's Bestseller – https://sheerluxe.com/2018/04/26/inspiring-true-story-set-be-summers-bestseller Is Having A Favourite Child Ever OK? – https://sheerluxe.com/2018/04/25/having-favourite-child-ever-ok 7 Australian Brands To Follow For Summer Inspo – https://sheerluxe.com/2018/04/20/7-australian-brands-follow-summer-inspo Special Guest:Visit The London Chatter: http://www.thelondonchatter.com/Follow The London Chatter: https://www.instagram.com/thelondonchatter/?hl=enGet SheerLuxe straight to your inbox, daily: http://sheerluxe.com/signupFollow SheerLuxe on Instagram: http://instagram.com/sheerluxeSheerLuxe VIP: https://sheerluxevip.com/ See acast.com/privacy for privacy and opt-out information.

As Charlotte's cult continues to grow, dark secrets are brought to light, while things best left buried are consigned to the fire. The chronicle's wiki can be found here.

Ask a beer lover, and there are plenty of cities whose names can be synonymous with the drink they love. San Diego, Grand Rapids, Portland, Fort Collins ... Portland again. In North Carolina, Asheville has long held that designation, gaining local and national attention, but part of the fun of watching beer’s growth can be the creation and explosion of cultures in new places. In recent years, that’s been the case in Charlotte, North Carolina, about two hours away from Asheville and now home to about 20 breweries and a burgeoning beer scene. One person who’s had a unique perspective of seeing this happen is Alexa Long, head brewer at Legion Brewing, an almost two-year-old business in the city’s Plaza Midwood neighborhood. After graduating from UNC-Charlotte in 2011 and working locally at a homebrew store, Long went pro at Charlotte’s Heist Brewing before joining Legion in fall 2015 and being a part of the crew that earned Legion the title of “best new neighborhood brewery” by Charlotte magazine in 2016.   Long’s connection to Charlotte provides her a unique perspective of how the city and its love of beer has changed, as drinkers have now come to expect more than just juicy IPA, even if that continues to be a bestseller for Legion and others. As Charlotte’s star continues to rise, Long has and continues to be a part of that.

Character comedian Charlotte McDougall is Gay Furnish - Flirt Coach, sexologist and dating guru. As Charlotte explains, Gay can change your life. First broadcast on Broadway Baby Radio in 2015. © 2015 On the Mic. For more info visit: http://onthemic.co.uk Produced by Voice Republic For more podcasts visit http://voicerepublic.com