Podcasts about Coa

  • 530PODCASTS
  • 1,279EPISODES
  • 38mAVG DURATION
  • 5WEEKLY NEW EPISODES
  • Mar 2, 2026LATEST

POPULARITY

20192020202120222023202420252026

Categories



Best podcasts about Coa

Show all podcasts related to coa

Latest podcast episodes about Coa

Federal Tax Updates
Tips, Overtime, and Meals: What's Actually Happening This Filing Season

Federal Tax Updates

Play Episode Listen Later Mar 2, 2026 58:09


Roger and Annie check in mid-tax-season with a candid look at what's actually landing on desks — from W-2s showing overtime pay coded a half-dozen different ways to clients convinced their entire salary qualifies for the new deduction. They also break down the meal and entertainment changes taking effect in 2026, including why your office coffee pot is now a tax problem.SponsorsPadgett -  Contact Padgett or Email Jeff PhillipsGet NASBA Approved CPE or IRS Approved CELaunch the course on EarmarkCPE to get free CPE/CE for listening to this episode.Chapters(00:00) - Mardi Gras Catch Up (01:53) - Tax Season Pulse Check (05:17) - New Tips and Overtime Law (07:07) - Tracking and Payroll Prep (10:58) - New Fees and Tip Confusion (12:46) - W2 Example Box 14 Codes (16:25) - Should We Ask About Overtime (20:36) - OT Premium Smell Test (24:39) - Weird W2 Overtime Codes (27:04) - Pay Stub Premium Math (29:25) - Pay Stub Math Costs (29:55) - Overtime Premium Basics (32:13) - W2 Box 14 Overtime (33:27) - When Details Are Missing (35:35) - Double Overtime Limits (36:18) - Salary vs Overtime Claims (38:36) - Due Diligence and Fees (41:01) - Meals Rules Change 2026 (45:01) - Zero Deduction Office Meals (45:37) - Coffee and Snacks Debate (48:59) - Client Education and COA (51:48) - IRS Paper Checks Ending (55:49) - Wrap Up and Next Steps Follow the Federal Tax Updates Podcast on Social Mediatwitter.com/FedTaxPodfacebook.com/FedTaxPodlinkedin.com/showcase/fedtaxpodConnect with the Hosts on LinkedInRoger HarrisAnnie SchwabReviewLeave a review on Apple Podcasts or PodchaserSubscribeSubscribe to the Federal Tax Updates podcast in your favorite podcast app!This podcast is a production of Earmark MediaThe full transcript for this episode is available by clicking on the Transcript tab at the top of this pageAll content from this podcast by SmallBizPros, Inc. DBA PADGETT BUSINESS SERVICES is intended for informational purposes only.

Let's Talk Wellness Now
Episode 256 – How Peptides Work, Benefits, and FDA-Approved vs Off-Label Use Explained

Let's Talk Wellness Now

Play Episode Listen Later Feb 27, 2026 41:38


What if the reason you’re not healing isn’t that you need another diagnosis? 0:08 It’s that your cells aren’t receiving the right signals. Because the body doesn’t run on diagnosis, it runs on 0:16 communication. And peptides are one of the most powerful, most misunderstood 0:21 tools we have for cellular signaling, immune balance, tissue repair, gut 0:27 lining support, metabolic control, brain signaling, sleep cycles, and even sexual 0:35 wellness. Today, I’m going to do what most people won’t. Define peptides in 0:41 plain English for you. break them into categories by what they’re best at and 0:47 tell you which ones are FDA approved on the list and which ones are commonly 0:53 used off label or investigational with the evidence that actually says these 1:00 work. This is going to be a powerful episode and if you’ve ever felt like you’re hearing hype without clarity, 1:07 this one’s for you. So, as usual, grab your cup of coffee or tea and settle in 1:13 as we talk about peptides that can fit into your healing journey. We’re going 1:19 to have a short word from our sponsor. You know, we got to do that. That’s how we stay on the air here. So, we will be 1:26 right back after this. Did you know sweating can literally heal your cells? 1:32I nfrared saunas don’t just relax you. They detox your body, balance hormones, 1:37 and boost mitochondrial energy. I’m obsessed with my health tech sauna. And 1:42 right now, you can save $500 with my code at healthtechalth.com/drmuthqen25. 1:54 All right, here we go, guys. I am excited to dive into peptides with you. 2:00 So understanding peptides is foundational, right? And I’ve been 2:06 studying peptides now for about nine years. Um, and I find that they are 2:13 incredible. Um, so I want to break down for you what peptides actually are, what 2:19 they do, and some of the top peptides that are available today, and how they 2:25 can be utilized. Because I think it’s really important. And I think it’s it’s there’s a lot of confusion out there about what these things actually are and 2:32 are they safe? Are they not? When do we use them? What’s the science behind them? So, we’re going to dive in and 2:38 we’re going to talk about all things peptides. So, let’s get ready here. Here we go. So, peptides are short chains of 2:45 amino acids and they typically range anywhere from 2 to 50 amino acids and 2:51 they’re linked by peptide bonds. So think of them as the superglue that holds the amino acids together. They sit 2:58 between the amino acids and they are full proteins in terms of their size and 3:04 their complex structure. And what makes peptides particularly interesting in 3:10 medicine is their role as signaling molecules. They’re essentially the 3:15 body’s text messages carrying specific instructions to cells and tissues. And 3:21 unlike our proteins which often serve as structural roles or act as enzymes, 3:28 peptides typically function as hormones, neurotransmitters and growth factors and 3:33 they bind to specific receptors on the cell’s surfaces or within the cells and 3:39 they trigger this effect. It’s like a cascade effect of a biochemical reaction 3:45 that ultimately changes the cellular behavior. So basically, it’s changing 3:50 the way the body’s cell structure acts. And this is why peptides can be so 3:56 incredibly powerful and therapeutic when you introduce the right peptide signal. 4:02 Now, you could theoretically redirect cellular processes toward healing, 4:07 towards metabolism, immune balance, tissue repair. Any of those things can 4:14 be manipulated to do a certain thing once we add the peptide. The challenge 4:19 in peptide medicine though lies in distinguishing between those peptides that have been rigorously studied, 4:26 proven safe and effective and approved by regulatory bodies like the FDA versus 4:31 those that exist in what we call the gray zone of a promising clinical data. 4:36 But they really lack human validation so far. And this distinction is critical because the presence of a plausible 4:43 mechanism does not guarantee safety or efficacy in living humans. So, this is 4:50 really important and we’re going to dive in and look at some of the research on all of these different peptides that are 4:56 available and I’m excited to say there’s some amazing peptides being studied right now that unfortunately are not 5:01 available. But I can’t wait to see them hit the market for us because it is going to be a gamecher as far as health 5:09 and longevity. So there is a quality control issue and there is a hidden 5:14 variable in peptide medicine with this and it’s one of the most underappreciated aspects of peptide 5:21 therapy particularly for non-FDA approved peptides. It’s quality control. 5:26 When we discuss pharmaceutical medicines, we take for granted that the pill contains what the label says. Not 5:32 always true depending on where it comes from. You guys, if you’ve heard my episodes before talk about how many of our medications are made in China and 5:41 have been contaminated with other things, you will realize that that is not always true. So, just because it has 5:48 the FDA stamp of approval on the medication, it still does not necessarily mean it’s safe and we still 5:54 need to do our homework on it. So, sorry for digressing on you guys, but you know, when we get a medication, we we 6:00 think that what the amount says is what is there, doesn’t have contaminants, it’s manufactured with good 6:06 manufacturing practices. You’ll see that listed as GMP on the bottle, and it’s been stored properly, it’s been 6:12 maintained stable, and with research peptides and compounded formulations, 6:17 none of this can be assumed. So, I will share a story with you. There was a gentleman that was purchasing these 6:24 peptides online from a research facility and um did not know that they were 6:30 coming from China and he was ordering a particular growth hormone peptide and 6:35 after a little while he had he had done fine for the few first few bottles. After a little while he started having 6:42 some complications. He started getting really irritable and angry and ragy and 6:47 he didn’t quite know what was going on. And so he decided to go get some testing done. He had some blood testing done and 6:53 his testosterone level was over 5,000. So for those of you who know what testosterone level should be for a guy, 7:00 they really shouldn’t be any higher than about 1,00200 would be absolute max that we’d want to see. Now he was taking 7:06 testosterone but not to that degree. And prior to adding this peptide, his 7:12 testosterone was very stable. What they ended up finding out was the peptide that he was getting, whoever was 7:18 manufacturing it added testosterone to the peptide. They felt like if if it had growth hormone, that was great, but if 7:25 it had growth hormone and tes testosterone, all the better. And he didn’t know that. And this is the 7:31 problem that we can have with peptides if you don’t source them properly. if you’re not working with somebody that 7:37 knows how to source them and can prove that they are what they say they are. Um, I’m sure there’s a whole bunch of 7:42 studies out there too of people getting these peptides and paying hundreds of thousands of dollars for them over their 7:48 lifetime and finding out they were nothing more than just sterile water. So, you really do need to be careful 7:53 with your quality control. Now, this kind of leads us right into the next topic that we’re going to talk about and that’s the manufacturing question, 8:00 right? The FDA approved peptides are manufactured in facilities subject to 8:05 the FDA inspection rules following our GMP regulations and these facilities 8:11 must validate their manufacturing process, demonstrate consistency batch to batch, test for purity and potency. 8:18 They need to test for bacterial endotoxins and sterility and they need to maintain detailed records. So, when a 8:25 pharmaceutical company submits a drug application, the FDA inspects the manufacturing facility as part of the 8:32 approval process. If you’re getting peptides from a different country, none of that is happening. And there are some 8:38 ways for us to determine if that is what you’re getting. Typically, the rule of thumb is if your peptides are coming 8:44 with a different colored top, every one of them has a different colored top. Those are typically being sourced out of 8:49 China. I wouldn’t say that’s 100% but that’s kind of the rule of thumb that people follow. So compoundingies these 8:56 are thearmacies that make our bio identical hormones. They can make medications in any dose or strength or 9:02 route. There are thousands of them in every not that not in every state but 9:08 there are thousands of them around the country right now. So these compoundingies are registered as 503A 9:15 facilities. They do traditional compounding for individual prescriptions, right? Like they can make 9:20 thyroid, they can make LDN, they can make estrogen. You can also have a 503b 9:27 facility, which is an outsourcing facility. And these companies produce larger batches of products. They’re they 9:34 have some oversight, but they’re less stringent than for FDA approved 9:40 manufacturers. And state boards of pharmacy regulate a 503A pharmacy. And 9:45 the FDA can inspect the 503b facility, but doesn’t preapprove any of their 9:52 compounding products. So, they can inspect it, but they don’t approve them. So, research chemicals and these 9:58 suppliers operate essentially with no oversight. They explicitly market products for research use only, not for 10:06 human consumption to avoid FDA regulation. If they put that on their 10:12 product, they don’t have to comply to what the FDA is saying. And there is no required manufacturing strategies or 10:19 standards, no required testing, no required sterility assurance, and no enforcement mechanisms if products are 10:26 mislabeled or contaminated. So basically, they don’t have the liability, but that doesn’t mean that 10:31 all of them are badies or bad suppliers. It just means they don’t have to comply 10:37 to the FDA rules. Now, there are many of these companies that I’ve seen and I’ve talked to that do do a lot of this. They 10:44 do test their product for sterility. They do test their product to make sure it is what it says it is. They don’t 10:51 have to, but they do. So, if you’re going to decide to use a company that 10:56 has research only, not for human consumption, at least ask for their 11:02 proof of testing so that you know that the product you’re getting is what it says it is and that it’s clean. Because 11:08 this is where we run into the problem is in purity. So in purity peptide 11:13 synthesis can produce not just the targeted peptide but also related 11:19 peptides with deletions, substitutions, truncations or truncations of amino 11:25 acids. Sorry. And this high performance liquid we call it uh chromatography can 11:30 separate these related impurities and quality and quantify the actual target 11:35 of the peptide content. So a certificate of analysis is what you want to ask these companies for. This shows the HPLC 11:44 the testing mechanism with greater than 95% or ideally 98% purity which 11:51 indicates a higher quality product. So this certificate of analysis can be fabricated may not represent the 11:57 specific batch being sold. It happens. We need to know not everybody is honest. Not everybody, you know, does what they 12:03 say and it does what’s right. But at least you at least they’re giving you something and you have some security. 12:10 and then choose a company that was referred to by someone else that has done some homework as well. In in 12:16 commercial research, there’s independent testing and they research peptides and this has been really shocking 12:23 variability that they’ve seen. Some products contain 50% or less of the 12:29 claimed peptide and some contained primarily degradation of the product or manufacturing impurities and some 12:36 contained bacterial endotoxins at levels that could cause fever and systemic 12:42 inflammation if it was truly injected. And I would also worry with some of those problems, you know, depending on 12:48 what impurity or bacterial endotoxin was there. If you’re using a product to boost your immune system and your immune 12:54 system is already compromised, these bacterial endotoxins can actually make you sicker instead of what you want it 13:02 to do, which is making you better. So, sterility is always an issue with anything that is manufactured, 13:08 especially things that we’re doing as an injection. Peptides are intended for injection. They must be sterile. They 13:16 must be kept safe. And pharmaceutical manufacturers conduct this sterility testing on every batch. 13:22 Compoundingarmacies should conduct sterility testing particularly for high-risisk compounded 13:28 sterile preparations and research chemical suppliers may or may not conduct any testing. So injecting 13:35 non-sterile material can cause local infections, abscesses at the injection 13:41 site and or if the bacteria enters the bloodstream could potentially be 13:46 life-threatening and you could have sepsis. Now, excuse me. We saw this 13:52 happen in a compounding pharmacy uh gosh, it’s probably been 10 years ago 13:57 now, I think. um they unfortunately had a strep uh contamination in their 14:03 product and they weren’t testing it. It was a large compounding pharmacy out of Florida and they were making products 14:08 that were being injected into the joints and um these people got very very sick 14:14 and some of them died and um some of them got very very injured by this uh 14:21 complication that happened. So it’s not like this doesn’t happen. It does, but it doesn’t happen often. And that’s what 14:28 we have to know about. And so, when we’re talking with you guys about storage and stability, it’s really 14:34 important to make sure you maintain your peptides well. So, many peptides are unstable at room temperature. They 14:41 require refrigeration or freezing. We tell everyone to make sure you’re refrigerating your peptides. That way, 14:48 there’s no question about it. when it stays cold um it prevents or slows down 14:54 the process of uh bacteria growing in it. So some of these peptides actually 14:59 degrade very rapidly in the solution and they must be reconstituted immediately before use and reconstitution of the 15:07 peptides really has limited stability often just days to weeks not months. So 15:13 improper storage, temperature, um changes during shipping or prolonged 15:19 storage of a reconstituted product can lead to degradation into inactivity or 15:25 potentially even a harmful breakdown of the product itself. So if you have a product that’s been sitting in your 15:30 refrigerator for a month or two months or 3 months or 6 months, just throw it away. It’s not going to be any good. 15:37 you’re not going to actually get the peptide and the uh potency that you’re looking for anyway out of it and the 15:44 potential of you introducing an endotoxin, a bacterial endotoxin is quite high at that point. So you just 15:50 really don’t want to take the risk, excuse me. So what practitioners, what 15:56 should we do and what should patients do? Well, for any peptide therapy, we 16:03 want to source our verification. know where the peptide product comes from. Is 16:08 it an FDA approved product? Is it a 503b compounding? A research chemical 16:14 supplier? Is there a certificate of analysis? Request and review this COA. 16:20 And you want it to show purity greater than 95% but ideally greater than 98%. 16:27 You want that identity be identity to be confirmed by mass spectromedy. Uh 16:33 sterility testing should be done. Bacterial endotoxin testing should be done. Batch number matching of the 16:39 product that you received should be done. Proper storage. You want to know that this has been refrigerated or 16:46 frozen as directed once it’s been mixed. Look at the expiration dates for reconstituting your peptides. Track that 16:53 reconstitution date and discarded accordingly like we just talked about. Monitor for your adverse effects. Even 17:01 with the perfect quality control, monitoring for adverse effects is essential with questionable quality and 17:08 vigilance is really critical here. I know it’s frustrating for a lot of patients when they have to get several 17:15 bottles and they only last a week or two. right here, you guys. This is why 17:21 they only last a short period of time because once they’re mixed, they start 17:26 to degrade and they won’t be good and you won’t get the benefit from it. So, 17:31 it’s really important with these research peptides specifically, practitioners should recognize that all 17:38 recommending products without quality assurance violates the fundamental medical principle of first do no harm. 17:45 If a patient is determined to use research peptides despite counseling, providing guidance on quality 17:52 verification, requesting those COAs, using pharmaceutical grade sources when available, proper testing, this all 17:59 reduces harm, but doesn’t constitute necessarily that recommendation. Now, 18:06 that being said, today it’s very difficult to find peptides by the compoundingies because of what the FDA 18:13 has done. So most of the peptides that are available to us have been labeled 18:18 not for human consumption, not because they’re not good products, but because 18:25 of what the FDA did. And this is how these companies have been able to 18:31 continue to provide peptides to the medical community. And if you know you 18:36 have a good company, then you’re, you know, you’re still taking the risk, right? But at the end of the day, the 18:42 reason they’re doing that is to protect themselves from the FDA, from liability. Um, so just kind of know that there is 18:50 some talk in the community with um Bobby Kennedy that this is going to change and 18:55 they are going to bring peptides back to the compounding pharmacies. Now, we don’t know which ones they’re going to 19:01 bring back. Uh, will it be all of them? Will it just be some of them? What’s going to happen here? Um, is it going to 19:07 go to the pharmaceutical companies like our GLP1s did? We don’t know what that’s going to look like quite yet. Um, but it 19:14 is coming and that is positive news. So, let’s talk now about FDA approved 19:21 peptide medications. So, this is the metabolic revolution, right? GLP1 19:28 and our dual increeting agonists. This is an exciting time. GLP-1s are amazing. 19:35 Um, a lot of people are skeptical, a lot of people love them, a lot of people hate them. Whichever side of the fence 19:42 that you’re on, I understand. But I want to talk about the science of it today 19:48 and what it actually means for people. So, the story of GLP1 glucagon like 19:54 peptide one represents one of the most significant advances in metabolic 19:59 medicine in the past several decades. GLP-1 is an accretin hormone. It’s 20:05 gutder derived peptide that potentiates insulin secretion in response to food 20:11 intake. And the body naturally produces GLP-1 in the intestinal L cells, but it 20:17 rapidly degraded by the enzyme DPP4 giving it a halflife of only about 2 20:24 minutes. So this rapid breakdown made in therapeutically impractical until 20:31 research was developed and modified the analoges that resist the enzyme degradation. So for those people who 20:39 never feel full when they’re eating, never feel satisfied when they’re done, this is because their body is either not 20:46 producing enough GLP1 or it’s not getting the signal right. And this is a 20:51 leptin issue. This is an insulin issue. It’s a GLP-1 issue. It’s a complicated 20:56 issue. This is not anything that the person is doing wrong. It’s what is happening to their body. And so GLP1s 21:03 have really revolutionized this. So one particular GLP-1 that we have is 21:09 semiglutide. And this GLP-1 agonist is what changed everything in the world of 21:16 metabolic medicine. Semiglutide is marketed as ompic for type 2 diabetes 21:23 and it’s marketed as WGOI for chronic weight management. It is a modified 21:29 GLP-1 analog with 95 or sorry 94% amino acid sequence uh homology to human 21:37 GLP-1. So it means that it’s it’s just like our own GLP-1 that we make. This 21:42 modification includes specific amino acid substitutions and the addition of C18 21:50 a fatty acid chain which allows the peptide to bind to albumin. Now this 21:56 albumin binding dramatically extends the half-life to approximately one week 22:01 enabling one weekly dosing which is a major advantage over the earlier GLP-1 22:07 agonists that require daily or twice daily injections. The mechanism by which 22:13 semiglutide works is multiaceted. At the pancreatin level, it binds to GLP-1 22:20 receptors on the pancreatic beta cells enhancing glucose depending sorry 22:27 enhancing glucose dependent insulin secretion. This glucose dependency is 22:33 crucial. It means the peptide only stimulates insulin release when blood glucose is elevated. This dramatically 22:41 reduces the hypoglycemic risk compared to insulin or even uh sulfuras. 22:47 Simultaneously semiglutide suppresses glucagon secretion from pancreatic alpha 22:53 cells further improving glycemic control. This is really amazing because 23:00 over the years when we’ve used insulin, which is also a peptide by the way, you 23:05 had to dose it just right because if you didn’t, you would produce so much insulin that it would crash the blood 23:12 sugar and then somebody would have too low of a blood sugar. They’d be hypoglycemic and they’d have to eat more 23:18 sugar and then they’d have to modify the insulin again and the person would be going up and down, up and down, up and 23:24 down all day long. And that created a lot of problems for people and so this 23:30 helps to stabilize that so it is not such an intense change. Now in the GI 23:36 tract semiglutide delays the gastric emptying particularly pronounced during 23:41 the initial weeks of therapy. This slowing of the gastric emptying contributes to the sensation of being 23:48 full and early satiety that patients often describe. However, this effect 23:54 tends to attend to weight over time as the body adapts through the appetite 24:00 suppressing effects generally persist through central mechanisms. So, when we 24:05 talk about what is actually happening, we’re slowing that digestive process down. That’s why people aren’t so 24:11 hungry. It’s why they’re not eating so much. This is why people can develop constipation with these products because 24:17 it’s slowing the body’s digestive tract down. Now some people will call this 24:22 gastroparesis. Um gastroparesis is actually different. 24:28 It is when we lose control over what’s happening in the in the colon like the 24:34 nerves and things like that just stop working. I have never seen that with the GLP1s that we prescribe in micro doing. 24:42 um it’s been documented. It can happen, but again it a lot of it is dosing and a 24:48 lot of it is staying on top of your client and what’s happening and what’s going on and what you’re doing and making sure that they do have good 24:54 motility still. So a lot of these things can be mitigated if you have problems 24:59 with them. Now one of the most profound effects of semiglutide occur in the 25:05 central nervous system. GLP-1 receptors are widely distributed in the brain 25:10 particularly in the hypothalamus and the brain stem area where we are involved in 25:15 appetite regulation. So when when wilding and colleagues published their 25:20 landmark step one trial in the New England Journal of Medicine in 2021, 25:25 they demonstrated that participants receiving 2.4 4 milligrams of semiglutide weekly achieved an average 25:32 weight loss of 14.9% of their body weight over 68 weeks. Now, I want you 25:39 guys to really understand this. We’re talking roughly 15% body weight loss 25:45 over a year, longer than a year. 52 weeks is a year, right? This is 68 25:50 weeks. So, it took longer for them to lose. We’re not talking about giving 25:55 somebody a dose to lose 15% of their body mass in a month or two. That that 26:01 is not healthy for any of us. That is not what we’re talking about doing here. Now, they compared this to placebo and 26:08 the placebo was only 2.4%. So, that is a significant difference. 26:14 And even beyond the numbers, patients reported something very qualitatively different, a reduction in what’s now 26:21 called food noise. Everybody knows what food noise is. We’ve talked about this long before GLP1. It’s that craving. 26:28 It’s that part of your brain that just keeps thinking about I want to eat something. You know, that was actually 26:34 reduced and they didn’t expect to see that happen. Now, this refers to the constant mental preoccupation with food, 26:42 the intrusive thoughts about eating, the difficulty in feeling satisfied. Semi-glutide appears to appears to 26:49 modulate reward pathways in the misolyic system reducing hedonic eating and food 26:57 cravings. Now there are also great cardiovascular effects of semiglutide 27:02 that extend beyond weight loss. Uh the sustained six and select trials 27:07 demonstrated significant reductions in major adverse cardiovascular events uh 27:14 mace in high-risisk populations. The select trial published in 2023 showed 27:20 that semiglutide reduced cardiovascular death, non-fatal myioardial inffection 27:25 and non-fatal stroke by 20% in adults with overweight or obesity and 27:31 established cardiovascular disease but without diabetes. So this suggests that 27:37 mechanisms beyond glucose control and weight loss possibly including 27:42 anti-inflammatory effects, improvements in endothelial function and favorable 27:47 changes to lipid profiles. Now I will tell you the clients that I work with that are on GLP1, 27:53 they will tell you that their inflammation has been significantly reduced. We are also seeing really 28:00 amazing results in lipid profiles. um part of its weight loss, but there is a 28:06 component to this that is lowering the triglyceride levels because it’s related to sugar and how the body’s processing 28:11 it. And we’re seeing better profiles, less need for statins as a result of 28:17 that. If if you want to listen to my episode on statins, I have one on that. Uh they are not my favorite medication. 28:24 I think it’s overprescribed and overused um and not really affecting or 28:29 addressing the problem. So these things can really be helpful. There’s also some 28:34 uh ramblings going on with GLP-1s saying that they may be able to help with 28:40 addiction in the future because of where they’re finding it affecting the brain and how it affects the food noise and 28:47 the cravings that we have for food and the addiction for food. Could it potentially help with other addictions 28:53 down the road? We’ll have to wait and see on that one. So semiglutide’s FDA prescribing information also includes a 29:00 box uh boxed warning about thyroid sea cell tumors. So in rodent studies 29:06 semiglutide caused dose dependent and treatment duration dependent sea cell 29:12 tumors at clinically relevant exposures. So while it’s unknown whether or not 29:17 semiglutide causes uh thyroid cancer tumors in humans and the rodent thyroid biology 29:26 differs significantly from humans, the drug is contraindicated in patients with a personal or family history of 29:33 medillary thyroid carcinoma or in patients with multiple endocrine neopl neoplasia syndrome type two. it is 29:42 uh contraindicated for safety effects with that. Um I have seen endocrinologists okay GLP1s to be used 29:50 in patients who’ve had other forms of thyroid cancer just not the meillary 29:55 thyroid cancer. So there is possibility there. Now the most common side effects 30:00 are gastrointestinal. It’s nausea affects about 20 to 44% of patients 30:06 depending on the formulation with diarrhea, vomiting, constipation, abdominal pain, and also frequently 30:13 reported in clinical trials. I see this in my clinic, too, especially dose dependent. Um, and it happens early on 30:20 when you’re first starting the medication, but seems to settle out over time. The one that I would add to this 30:26 that I don’t think they have on here is an increase in acid reflux. We also see that quite often uh especially in people 30:33 who suffer with acid reflux to begin with. Now these effects are typically most 30:40 pronounced during the escalation and they like I said often improve over time 30:45 but more serious but less common adverse effects include acute pancreatitis. 30:51 The medication needs to be discontinued immediately if this is confirmed. You can see some diabetic retinopathy 30:57 complications in patients with pre-existing retinopathy and acute kidney injury. Um, this usually happens 31:05 secondarily to dehydration from the GI effects. There are some gallbladder disease um that can occur and people who 31:13 have a sensitive gallbladder will describe uh discomfort with that. I’ve 31:18 even seen some people who’ve had their gallbladder out on GLP1s at the higher doses complain of similar pain that they 31:25 used to have when their gallbladder was in. So, really important to just kind of monitor these symptoms and work closely 31:32 with somebody that understands them and can be on top of them quite quickly if this happens. Excuse me. From an 31:39 integrative medicine perspective, semiglutide really represents a powerful tool, but it’s not a standalone 31:46 solution. Remember, the medication addresses one aspect of the metabolic dysfunction, the signaling systems 31:53 controlling appetite and glucose homeostasis, but it doesn’t address the root cause that led to the metabolic 32:00 disease in the first place. Patients who rely solely on the medication without addressing the ultrarocessed food 32:07 consumption, the ccadian disruptions, the chronic stress, the sleep apnea, or 32:12 underlying hormonal imbalances often experience weight regain when the medication is discontinued. 32:20 The drug is also not a substitute for addressing the emotional and psychological drivers of eating 32:26 behavior, including the unresolved trauma that may manifest as emotional eating. I think this is really important 32:33 because we don’t address the trauma issue enough with clients and we need to 32:38 be looking at that. There is a huge trauma effect out there these days that is I don’t want to say leading to or 32:45 causing but it is definitely contributing to chronic illness and it’s not being talked about enough. So we 32:52 really need to be talking about this and addressing this trauma aspect. Now the next GLP that one that I want to talk 32:59 about is trespathide. This is a dual agonist. It takes center stage. It is my 33:05 favorite GLP one. Trisepatide is marketed as Mangjaro for type 2 diabetes 33:11 and Zepbound for chronic weight management and it represents the next 33:16 evolution in increantbased therapy. This is a dual agonist a 39 amino acid 33:23 synthetic peptide structurally based on the human glucose dependent insulin tropic peptide so GIP sequence but 33:31 modified to activate both the GIP receptors and the GLP1 receptors. So the 33:37 addition of the GI GIP agonism to the GLP1 agonism appears to create this 33:46 synergistic effect that goes beyond simply adding the two mechanisms together. So the GIP like GLP-1 is an 33:55 increant hormone secreted by what is called the K cells in response to nutrient intake. It enhances glucose 34:02 dependent insulin secretion but it also effects on atapost tissue metabolism 34:09 potentially improving the insulin sensitivity in fat cells and influencing 34:14 how the body stores and metabolizes fat. So some research suggests that GIP may 34:20 also have effects on energy expenditure though this remains an area of 34:26 investigation. So basically what we’re saying is this drug may actually help 34:32 people who are insulin resistant or insulin sensitive, not just somebody who 34:38 has problems with glucose control. So, this is super exciting because it opens 34:43 up the door for all of these people for decades that we’ve been trying to manage with insulin resistance and trying to 34:50 prevent diabetes and honestly most of the time have been unsuccessful 34:56 unless you can keep your diet at 50 grams of carbs or less a day, which is extremely difficult. Um, and take some 35:04 supplements that may or may not work and or take some metformin that may or may not help. this drug actually really 35:11opens that up and helps in that capacity. So there was a clinical trial 35:17 called the surmount clinical trial which demonstrated that trespathide produces 35:22 even more substantial weight loss than semiglutide. In the surerount one trial published by uh J tree I might have said 35:31 that wrong. I apologize if I slaughtered your name and colleagues in the New York England Journal of Medicine in 2022. 35:38 Participants receiving the highest dose of trespide, which is 15 milligrams, achieved an average weight loss of 20.9% 35:47 of their body weight over 72 weeks, compared to 3.1% with placebo. This 35:54 level of weight loss approaches what’s typically only seen in beriatric surgery. So, this is amazing because if 36:02 this medication works and we don’t have to do beriatric surgery, stomach stapling basically, um, oh my gosh, it’s 36:11 amazing. There are so many complications and risks that go with stomach stapling and the different procedures that they 36:17 do these days. People don’t absorb their nutrients properly. They have to do liquid nutrients. It’s very complicated. 36:24 It’s very challenging. Many of these people gain their weight back. Um, and 36:30 this procedure is not fun to go through. So, if we could change that and change 36:35 the lives of people who’ve really been struggling, it is amazing. And I will tell you that I have seen this work. I 36:42 have seen people lose 100 150 pounds on these medications over a year or two 36:50 period of time. It is definitely slower than beriatric surgery on some standpoints, but that is okay. You don’t 36:56 want that rapid weight loss. It’s not good for you. It’s not healthy for you. It doesn’t look well. You know, we want 37:03 to do this safely and effectively in the best way that we can possibly do that for you. Now, the adverse effect profile 37:10 is similar to semiglutide. It’s dominated by gastrointestinal effects. 37:15 Nausea, diarrhea, decreased appetite, vomiting, constipation. These were all commonly reported in the surmount 37:22 trials. And like semiglutide, tricepide carries a blackbox warning regarding the 37:27 thyroid sea cell tumors based on the rodent data and it shares the same contra indications in patients with a 37:34 family history of thyroid cancer and men too. So the mechanism behind why 37:40 tepatide often produces more substantial weight loss than GLP-1. The agonism 37:45 alone remains under investigation, but it may relate to the complimentary effects on the different aspects of 37:51 energy homeostasis or to GIP’s effects on atapost tissue and potentially on 37:58 central central nervous system pathways that GLP1 alone doesn’t fully address. 38:03 Now patients often report even more profound reductions in food noise with tricepide compared to GLP1 and uh sorry 38:12 GLP1 the agonists through this is anecdotal and hasn’t been regularly 38:17 quantified in quality studies. So I’ve done both uh personally and in my 38:22 practice. I really like trespide better than semiglutide. For me I had too many side effects with semiglutide. uh I had 38:30 less side effects with trespathide. I also plateaued on semiglutide which I 38:35 didn’t really care for. And with Tresepide, I haven’t plateaued and I’ve been able 38:42 to lose about 25 pounds in um a year and a half and I’ve been able to maintain 38:49 that. Um and I continued to use it because I do have a strong family history of cardiovascular disease. And 38:56 if this could help me so that I don’t follow my family lineage with cardiovascular disease, I am all for 39:03 trying to do that. I’ve watched too many of my family members suffer from this. I’ve lost my dad at a very young age. I 39:09 lost my grandfather at a young age to it. All of their brothers to this. And I don’t want to be that same person. So 39:16 that is why I chose to do that. And I think it’s really important for us to take a look at that and understand that. 39:24 Now, I know this has been a really long podcast and I don’t typically do podcasts this long. I have a whole host 39:31 of information on additional peptides. So, I’m going to break this up for you 39:36 guys and I’m going to do another episode and we’re going to pick up where we left off here with these peptides so that we 39:43 can actually start to dive into different peptides as well. So, check 39:48 out my next podcast show when we’re going to dive into the peptides that 39:54 talk about sexual wellness, immune function, and all the other cool things 39:59 that we can do with peptides. So until then, remember to like, share, and 40:04 subscribe. It really helps us get out to other people and share our information, 40:10 and join us for our next episode as we continue the talk about peptides. 40:15 Welcome to Let’s Talk Wellness Now, where we bring expert insights directly to you. Please note that the views and 40:21 information shared by our guests are their own and do not necessarily reflect those of Let’s Talk Wellness Now, its 40:28 management, or our partners. Each affiliate, sponsor, and partner is an 40:34 independent entity with its own perspectives. Today’s content is provided forformational and educational 40:40 purposes only and should not be considered specific advice, whether financial, medical, or legal. While we 40:48 strive to present accurate and useful information, we cannot guarantee its completeness or relevance to your unique 40:56 circumstances. We encourage you to consult with a qualified professional to address your 41:01 individual needs. Your use of information from this broadcast is entirely at your own risk. By continuing 41:08 to listen, you agree to indemnify and hold Let’s Talk Wellness Now and its 41:14 associates harmless from any claims or damages arising from the use of this 41:20 content. We may update this disclaimer at any time and changes will take effect 41:26 immediately upon posting or broadcast. Thank you for tuning in. We hope you 41:31 find this episode both insightful and thought-provoking. Listener discretion 41:36 is advised.The post Episode 256 – How Peptides Work, Benefits, and FDA-Approved vs Off-Label Use Explained first appeared on Let's Talk Wellness Now.

Just Focus
#C&C Notaires - Cession d'entreprise ? Les recommandations d'un notaire pour l'anticiper - avec Pierre Cénac

Just Focus

Play Episode Listen Later Feb 26, 2026 61:18


On prépare toujours la vente de son entreprise comme une opération financière ou stratégique. On oublie souvent sa dimension personnelle. Or c'est parfois céder le projet d'une vie — voire d'une famille entière. Beaucoup de dirigeants parviennent à cette étape sans avoir sécurisé l'essentiel : les risques personnels, la gouvernance et la structuration patrimoniale, autant de sujets qui peuvent faire dérailler la vente de l'entreprise bien dès le début du processus.Et dans cette histoire, le notaire reste trop souvent l'appel de dernière minute… alors qu'il devrait être l'un des premiers autour de la table.Me Pierre Cénac est notaire associé fondateur de C&C Notaires, étude qui s'est imposée comme une référence dans l'accompagnement des chefs d'entreprise, sur tout ce qui entoure une cession ou une transmission : protection du dirigeant et de sa famille, structuration de la détention, anticipation des risques et préparation de l'après etc.Dans ce 4e épisode de la série M&A, il décrypte la cession d'entreprise avec le regard du notaire et met en lumière les risques patrimoniaux, familiaux et juridiques que beaucoup de dirigeants ne découvrent… qu'au dernier moment.Au programme :Le rôle du notaire dans une cession d'entreprise, de l'anticipation au redéploiement du prix de cession.Les diagnostics indispensables à réaliser avant de céder son entreprise : situation personnelle, dépersonnalisation de l'entreprise, gouvernance, indépendance patrimoniale...Vendre ou transmettre à ses enfants ? Découvrez pourquoi la plupart des dirigeants hésitent, quels critères objectifs regarder pour trancher, et quels outils activer pour organiser une transmission stable.Les chocs de vie (divorce, incapacité, décès), leur impact dévastateur sur une entreprise non préparée et les protections à mettre en place avant que l'urgence ne s'impose.Les conseils de Me Pierre Cénac pour aborder une cession ou transmission d'entreprise sereinement, sans précipitation et sans mauvaise surprise.-----------------------Quelques ressources pour aller plus loin : Téléchargez le guide complet de la cession d'entreprise édité par Sapians : https://sapians.com/blog/guide-complet-cession-entrepriseCession d'entreprise : tout ce que vous devez savoir https://sapians.com/blog/cession-entrepriseCession d'entreprise ou de titres : cas d'exonération des plus-values possibles https://sapians.com/blog/exoneration-plus-values-cession-entrepriseTransmission d'entreprise : 5 stratégies fiscales à connaître https://sapians.com/blog/transmission-entrepriseTout savoir sur la donation avant cession : procédure, avantages et exemples https://sapians.com/blog/donation-avant-cessionTransmettre son patrimoine sans enfant : cadre juridique, fiscalité et stratégies pour dirigeants https://sapians.com/blog/succession-dirigeant-sans-enfant-----------------------Attention : Ceci est une communication publicitaire. Les performances passées ne préjugent pas des performances futures et investir comporte des risques de perte partielle ou totale en capital. Ce contenu est informatif et ne constitue pas un conseil en investissement. Toute décision doit être adaptée à votre situation. Si vous souhaitez bénéficier de conseils personnalisés, veuillez créer votre compte ou prendre rendez-vous avec un conseiller Sapians.SAPIANS - RCS n°919 330 969 - ORIAS n°23003561 en qualité de CIF et COA. Activité de démarchage bancaire et financier.

Efervesciencia
Efer 729 (1-1-26): Desde o Macondo outro ano de ciencia (Parte 2)

Efervesciencia

Play Episode Listen Later Feb 24, 2026 56:50


Desde o pub Macondo da Coruña coa música ao vivo do piano de Juanjo Fernández realizamos o noso repaso á mellor ciencia do ano. Coa participación dos nosos colaboradores Marta Vila, Susana Ladra, Deborah García Bello, Estíbaliz Espinosa e Xabier Pérez Couto. Parte 2.

Efervesciencia
Efer 728 (30-12-25): Desde o Macondo outro ano de ciencia (Parte 1)

Efervesciencia

Play Episode Listen Later Feb 21, 2026 57:35


Desde o pub Macondo da Coruña coa música ao vivo do piano de Juanjo Fernández realizamos o noso repaso á mellor ciencia do ano. Coa participación dos nosos colaboradores Marta Vila, Susana Ladra, Deborah García Bello, Estíbaliz Espinosa e Xabier Pérez Couto. Tamén conversamos con Manuel Díaz de Sotavento, que nos debulla o achado do ano. Parte 1.

Just Focus
#Clipperton - Financement non dilutif : ce que les dirigeants sous-estiment avant de lever de la dette - avec Laurence de Rosamel

Just Focus

Play Episode Listen Later Feb 19, 2026 35:22


L'essor de la dette privée a changé la donne pour les dirigeants : plus besoin de sacrifier son capital pour financer une acquisition ou une liquidité actionnariale. Mais le financement en dette privée, certes non dilutif, obéit à ses propres règles et sa mécanique exigeante n'est pas toujours bien comprise.Banque d'affaires indépendante spécialisée dans la tech, Clipperton accompagne depuis plus de 20 ans les entrepreneurs européens dans leurs opérations stratégiques : M&A, levées de fonds et financements structurés.Dans ce 3e épisode de la série M&A, nous recevons Laurence de Rosamel, banquière d'affaires chez Clipperton, qui a lancé l'activité dédiée aux financements non dilutifs. Elle accompagne les dirigeants dans la structuration de dettes bancaires ou privées pour optimiser leur coût du capital et sécuriser leurs opérations de croissance ou de cession.Au programme :Les options pour financer la croissance de sa société, leurs spécificités et les risques associés (dette bancaire, dette privée, mezzanine ou fonds propres)Comment arbitrer entre financement dilutif et non dilutif selon le profil de risqueLes spécificités du financement des sociétés technologiques (ARR, croissance, rentabilité pilotée)Les conseils de Laurence pour choisir la bonne structure de financement et le bon timing.-----------------------Quelques ressources pour aller plus loin : Téléchargez le guide complet de la cession d'entreprise édité par Sapians : https://sapians.com/blog/guide-complet-cession-entrepriseDette unitranche : définition et avantages de ce type de financement https://sapians.com/blog/dette-unitrancheCession d'entreprise : pourquoi associer banque d'affaires et gestionnaire de fortune ? https://sapians.com/blog/banque-d-affaires-vs-gestionnaire-de-fortune-cession-entrepriseUne banque d'affaires est-elle indispensable pour céder sa société ? https://sapians.com/blog/cession-pme-avantages-limites-banque-d-affairesRachat avec effet de levier : tout savoir du LBO ou Leveraged buy-out  https://sapians.com/blog/definition-lboCession d'entreprise ou de titres : cas d'exonération des plus-values possibles https://sapians.com/blog/exoneration-plus-values-cession-entreprise-----------------------Attention : Ceci est une communication publicitaire. Les performances passées ne préjugent pas des performances futures et investir comporte des risques de perte partielle ou totale en capital. Ce contenu est informatif et ne constitue pas un conseil en investissement. Toute décision doit être adaptée à votre situation. Si vous souhaitez bénéficier de conseils personnalisés, veuillez créer votre compte ou prendre rendez-vous avec un conseiller Sapians.SAPIANS - RCS n°919 330 969 - ORIAS n°23003561 en qualité de CIF et COA. Activité de démarchage bancaire et financier.

The College Admissions Process Podcast
359. Financial Aid - Anne Rusk - Associate Director of Financial Aid - Colorado School of Mines

The College Admissions Process Podcast

Play Episode Listen Later Feb 18, 2026 43:08


Cannabis School
Utah Strain Spotlight: Pure Michigan by Beehive

Cannabis School

Play Episode Listen Later Feb 17, 2026 39:26


What is Pure Michigan actually built to do?Pure Michigan is not a “wake up and conquer the world” strain. It's usually a heavy hybrid that leans indica in feel, built more for depth than sparkle.This cultivar is commonly bred from Oreoz x Mendo Breath, which already tells you something. Both parents are known for dense structure, rich flavor, and body-forward effects.From Beehive Farmacy, batch specifics always matter, so check your label. But here's what Pure Michigan typically looks like chemically.• THC often in the high teens to mid 20 percent range• Very low CBD• Minor cannabinoids like CBG sometimes present in small amountsTranslation: this is THC dominant. If your tolerance is low, it can get heavy fast. This is not a microdose-first strain unless you intentionally keep it that way.Common dominant terpenes in Pure Michigan:• Caryophyllene• Myrcene• LimoneneCaryophyllene is the spicy, peppery terpene that also interacts with CB2 receptors, often associated with body relief.Myrcene leans sedating in higher concentrations.Limonene can add a slight mood lift or brightness.When myrcene and caryophyllene sit high together, you usually get that “deep exhale” body experience. Muscles loosen. Thoughts slow. The edges soften.Not guaranteed. But that's the tendency.At moderate doses:• Strong body relaxation• Slower mental pace• Warm, heavy calm• Possible couch gravityAt higher doses:• Sleep pressure• Brain fog• Hard pivot into “I'm done for the night”This is typically not a strain people use for high productivity. It leans evening. Recovery. Decompression.Who is this for:• People looking to wind down• Evening use• Body tension• High stress daysWho should be cautious:• Anyone sensitive to sedation• Anyone needing mental sharpness• New consumers jumping straight into large dosesThe real takeaway here is this: Pure Michigan is more about weight than sparkle. If you're chasing heavy body calm, it usually delivers. If you're chasing clarity and energy, this probably isn't your lane.And like we always say, strain names are branding. The batch chemistry is the truth. Always read the COA. Always start lower than you think.Utah cannabis makes more sense when you stop chasing names and start reading numbers.Keep the Mic on.Fuel the movement. Keep the conversation going.We keep a running list of tools and brands we personally enjoy and actually use.Find everything in one place here:

Grandes Voces do Noso Mundo
EP. 423: Sem Norte

Grandes Voces do Noso Mundo

Play Episode Listen Later Feb 15, 2026 60:42


Coa música da Sara Alhinho, abrimos esta nova entrega do Grandes Vozes. De Cabo Verde, viaxamos para outros países a onde chegou o noso idioma.

Just Focus
#Cambon Partners - Le M&A a changé ! Un banquier d'affaires dévoile les nouvelles règles pour les entrepreneurs - avec David Salabi

Just Focus

Play Episode Listen Later Feb 12, 2026 41:29


Vendre son entreprise, faire entrer un fonds, organiser un cash-out... Ces décisions stratégiques soulèvent des questions essentielles pour tout entrepreneur : comment bien préparer une transaction ? Quelle valorisation viser ? Comment gérer la négociation ?David Salabi a fondé Cambon Partners en 2003, sur les cendres de la bulle internet. Aujourd'hui, sa banque d'affaires indépendante réalise entre 50 et 60 opérations par an dans le mid-market et accompagne les entrepreneurs de la tech, du digital, de la santé ou encore du commerce dans leurs opérations de cession et de levée de fonds.Dans ce 2e épisode du hors-série M&A, David Salabi, après avoir supervisé 500 opérations M&A, nous livre avec transparence ses enseignements de banquier d'affaires.Au programme :Le “vrai” déroulé d'un process M&A vu de l'intérieur, avec les micro-décisions qui changent le deal avant même que la data room ne s'ouvre.Comment les opérations de LBO avec cash-out sont devenues vertueuses pour les entrepreneurs et pourquoi "dérisquer patrimonialement" le chef d'entreprise peut même booster la performance de l'entreprise.Pourquoi certaines entreprises se valorisent mieux qu'en 2022, ce que recherchent vraiment les fonds d'investissement aujourd'hui, comment éviter les attentes irréalistes et garder le contrôle.Les erreurs de posture côté dirigeant et le réflexe simple qui protège la valorisation jusqu'à la négociation finale.-----------------------Quelques ressources pour aller plus loin : Téléchargez le guide complet de la cession d'entreprise édité par Sapians : https://sapians.com/blog/guide-complet-cession-entrepriseLes étapes de la cession d'entreprise : bonnes pratiques et pièges à éviter https://sapians.com/blog/cession-entrepriseCession d'entreprise : pourquoi associer banque d'affaires et gestionnaire de fortune ? https://sapians.com/blog/banque-d-affaires-vs-gestionnaire-de-fortune-cession-entrepriseUne banque d'affaires est-elle indispensable pour céder sa société ? https://sapians.com/blog/cession-pme-avantages-limites-banque-d-affairesRachat avec effet de levier : tout savoir du LBO ou Leveraged buy-out  https://sapians.com/blog/definition-lboCession d'entreprise ou de titres : cas d'exonération des plus-values possibles https://sapians.com/blog/exoneration-plus-values-cession-entreprise-----------------------Attention : Ceci est une communication publicitaire. Les performances passées ne préjugent pas des performances futures et investir comporte des risques de perte partielle ou totale en capital. Ce contenu est informatif et ne constitue pas un conseil en investissement. Toute décision doit être adaptée à votre situation. Si vous souhaitez bénéficier de conseils personnalisés, veuillez créer votre compte ou prendre rendez-vous avec un conseiller Sapians.SAPIANS - RCS n°919 330 969 - ORIAS n°23003561 en qualité de CIF et COA. Activité de démarchage bancaire et financier.

Kaya Cast
Taste Like a Treat: How Good Feels Optimized Flavor and Potency

Kaya Cast

Play Episode Listen Later Feb 10, 2026 59:12


On this Kaya Cast episode, host Tommy Truong chats with Jason Reposa, founder of Good Feels, the team behind the Good Vibes fast-acting tinctures and hemp beverages. Jason shares his founder journey—from selling a media business to embracing a mission-driven cannabis tech company—and how a focus on liquid formats delivers fast, precise dosing across high- and low-dose customers. Learn how Good Feels evolved from early beverage experiments to a syrup-based, drink-friendly delivery that can be dosed from 5 mg to 1000 mg per one-ounce bottle, with onset in roughly 10–15 minutes. The discussion covers product iteration, taste optimization, and the balance between consumer education and regulatory realities in Massachusetts, including hemp versus cannabis rules and COA transparency. Jason offers candid perspectives on marketing versus sales, in-store partnerships, sampling strategies, and the need for strong branding to stand out in a crowded market. If you're a dispensary owner, buyer, or brand founder, you'll gain actionable insights on product development, category positioning, retailer partnerships, and building a brand that makes people feel good—and empowers them to do more good. Find out more about Good Feels at:https://getgoodfeels.com/https://www.linkedin.com/in/jasonreposa/https://www.linkedin.com/company/good-feels/ 00:00 Introduction and Guest Background00:29 Journey into the Cannabis Industry01:37 Product Development and Market Reception03:34 Personal Motivation and Business Evolution13:33 Challenges and Innovations in the Beverage Market22:32 Marketing Strategies and Consumer Insights30:33 Target Audience: High Dose Consumers31:59 Product Development Journey33:24 Challenges in the Cannabis Market35:49 Product Improvement and Feedback39:55 Cannabinoid Innovations and Regulations46:55 Marketing and Retail Partnerships53:40 Rapid Fire Questions and Personal Insights57:13 Mission and Vision of Good FeelsKaya Cast podcast, Kaya Cast episode, cannabis business podcast, cannabis industry podcast, hemp beverage podcast, fast acting cannabis tinctures, liquid cannabis dosing, fast onset THC products, fast acting hemp drinks, cannabis beverage innovation, cannabis tincture technology, liquid cannabis delivery systems, precise THC dosing, low dose THC products, high dose THC tinctures, microdose cannabis products, high potency hemp tinctures, syrup based cannabis beverages, drink friendly cannabis syrup, 10 to 15 minute onset cannabis, fast acting hemp tincture Massachusetts, cannabis beverage market trends, cannabis product development insights, cannabis founder journey, cannabis startup story, mission driven cannabis brands, cannabis branding strategy, cannabis category positioning, dispensary product buying insights, dispensary buyer education, cannabis retail partnerships, in store cannabis sampling strategies, cannabis sales versus marketing, cannabis consumer education, cannabis regulatory compliance Massachusetts, hemp versus cannabis regulations MA, cannabis COA transparency, hemp COA compliance, cannabis beverage dosing accuracy, cannabis tincture taste optimization, cannabis product iteration process, cannabis innovation leadership, cannabis beverage manufacturing, hemp beverage formulation, cannabis syrup formulation, cannabis liquid formats, cannabis drink additives, cannabis wellness beverages, functional cannabis drinks, cannabis brand differentiation, standing out in cannabis retail, dispensary shelf strategy, cannabis merchandising insights, cannabis buyer decision making, cannabis retailer partnerships US, cannabis distribution strategy Massachusetts, Massachusetts cannabis market insights #kayacast #cannabis #tips #dispensaries #business #podcast

Metabolism Made Easy
Nitrogen Disposal & Carbon Skeletons- AI Podcast

Metabolism Made Easy

Play Episode Listen Later Feb 10, 2026 2:59


The body cannot store excess amino acids, so they are used for protein synthesis or energy. During catabolism, nitrogen is converted into toxic ammonia, which the urea cycle safely removes. Remaining carbon skeletons are repurposed for fuel by producing glucose or acetyl CoA which are both catabolized to produce energy.

Course Epique
[L'ÉLAN] Ulrich Ndjike, rendre le trail accessible à tous

Course Epique

Play Episode Listen Later Feb 6, 2026 49:36


Ulrich Ndjike est éducateur sportif et passionné de montagne. Il a co-créé le COA, Club Outdoor Alpin basé à Annecy, une structure pas comme les autres, qui propose à des jeunes de quartier de découvrir la montagne, un univers qu'ils perçoivent parfois comme inaccessible, voire totalement étranger.À travers la course à pied, la randonnée et plus largement les activités outdoor, Ulrich cherche à ouvrir des horizons et à transmettre des valeurs fortes.Le travail mené par le COA a d'ailleurs été récompensé récemment, avec le prix de l'initiative sociale de l'année lors des Trail Running Awards.Dans cet épisode, on va parler d'élan. Pas seulement de celui qu'Ulrich a trouvé dans la course à pied, mais surtout de celui qu'il transmet à des jeunes pour leur donner l'envie et les moyens, de découvrir l'univers de la montagne.L'Élan, c'est le format court de Course Épique. Ici, on partage l'actualité des belles histoires de course à pied — des histoires vraies, simples et inspirantes. En moins de 30 minutes, on part à la rencontre de celles et ceux qui trouvent, dans la course, l'énergie d'écrire leur propre histoire. Des récits sincères et positifs, dans lesquels chacun peut se reconnaître.Louise Penhoat, athlète de haut niveau, y partage avec vous ces moments qui donnent envie d'enfiler ses baskets… et d'aller de l'avant.Alors, vous êtes prêts à prendre votre élan avec eux ?***Course Épique, c'est le podcast running et trail qui vous fait vivre, dans chaque épisode, une histoire de course à pied hors du commun.

Just Focus
#Archers - Cession d'entreprise : les points juridiques incontournables d'un deal M&A réussi - avec Marc Baffreau (avocat d'affaires)

Just Focus

Play Episode Listen Later Feb 5, 2026 58:40


De la due diligence au closing, une cession d'entreprise dure en moyenne plus de 6 mois et implique bien plus que des négociations de prix. Gouvernance, modalités de paiement, conditions suspensives... Comment se déroule concrètement une opération de cession ? Quelles sont les points juridiques clés d'une transaction M&A et les pièges à éviter ?Nous ouvrons ce hors-série sur les opérations de cession-acquisition avec Marc Baffreau, avocat d'affaires et co-fondateur du cabinet Archers, spécialisé en M&A et financement. Il accompagne dirigeants, acquéreurs et investisseurs sur leurs opérations de cessions d'entreprise, acquisitions, build-up et LBO.Dans cet épisode, nous décortiquons avec Marc :Le rôle de l'avocat transactionnel dans une cession : comment il intervient de la préparation de l'entreprise jusqu'au closing, en articulation avec les banquiers d'affairesLes étapes d'une transaction M&A : vendor due diligence, paramétrage du deal, manifestations d'intérêt, phase d'exclusivité... et pourquoi céder son entreprise prend désormais souvent plus de 6 moisCe qui se négocie au-delà du prix : modalités de paiement (cash vs earn-out), gouvernance, management package et pourquoi le candidat le plus offrant n'est pas toujours retenuLes points de friction dans une cession : évaluations erronées des dirigeants vendant pour la première fois, attentes irréalistes sur la gouvernance post-closing, conditions suspensives (Mac clauses, financement...)Les conseils de Marc pour réussir sa cession d'entreprise et éviter les erreurs classiques des cédants-----------------------Quelques ressources pour aller plus loin : Téléchargez le guide complet de la cession d'entreprise édité par Sapians : https://sapians.com/blog/guide-complet-cession-entrepriseLes étapes de la cession d'entreprise : bonnes pratiques et pièges à éviter https://sapians.com/blog/cession-entrepriseCession d'entreprise : pourquoi associer banque d'affaires et gestionnaire de fortune ? https://sapians.com/blog/banque-d-affaires-vs-gestionnaire-de-fortune-cession-entrepriseUne banque d'affaires est-elle indispensable pour céder sa société ? https://sapians.com/blog/cession-pme-avantages-limites-banque-d-affairesOptimisation fiscale lors de la cession de son entreprise : comment réduire l'imposition des plus-values ?  https://sapians.com/blog/optimisation-fiscale-cession-entreprise Cession d'entreprise ou de titres : cas d'exonération des plus-values possibles https://sapians.com/blog/exoneration-plus-values-cession-entreprise-----------------------Attention : Ceci est une communication publicitaire. Les performances passées ne préjugent pas des performances futures et investir comporte des risques de perte partielle ou totale en capital. Ce contenu est informatif et ne constitue pas un conseil en investissement. Toute décision doit être adaptée à votre situation. Si vous souhaitez bénéficier de conseils personnalisés, veuillez créer votre compte ou prendre rendez-vous avec un conseiller Sapians.SAPIANS - RCS n°919 330 969 - ORIAS n°23003561 en qualité de CIF et COA. Activité de démarchage bancaire et financier.

Christ Over All
5.05 Steve Deace, David Schrock, & Stephen Wellum • Interview • "What's Best Next: Abortion, Abolitionism, and Strategizing Ways to Save Lives and Change Laws"

Christ Over All

Play Episode Listen Later Jan 29, 2026 38:35


ABOUT THE EPISODEListen in to a special interview as COA's David Schrock and Stephen Wellum are joined by Steve Deace to talk about the best way to strategize and save lives, including a breakdown of the state of the Pro-Life and Abolitionist movements.Timestamps00:42 – Intro05:16 – How Do We Think About Incrementalism & Abolitionism? What is Most Effective?13:30 – What are Steps We Can Take to Disciple Zealous Brothers?22:17 – What is Recommended for Our Churches?26:57 – What Media is Most Effective in This Battle?30:50 – The Groundwork that Must Be Laid32:36 – What Would You Say for Pastors Who Consider This Too Political?36:27 – OutroResourcesThe Steve Deace ShowThe SBC's Turning Point (ft. Steve Deace) – Center For Baptist LeadershipTheme of the Month: Abolishing Abortion, Advocating for LifeGive to Support the Work

Just Focus
#21 Se financer en equity, en dette, faire un cash-out et tout réinvestir dans l'impact - avec Thibault Lamarque

Just Focus

Play Episode Listen Later Jan 29, 2026 64:20


Thibault Lamarque est le fondateur de Castalie, entreprise pionnière de l'eau microfiltrée en France, lancée en 2011. A 30 ans, après un début de carrière en finance (notamment chez Veolia), il a développé un modèle par abonnement qui a permis de déployer plus de 7 500 fontaines.La croissance de Castalie s'est structurée autour de leviers successifs : fonds propres, friends & family, fonds en equity, puis de la dette avec Pictet afin de financer l'accélération sans dilution.Dans cet épisode, Thibault revient sur sa stratégie de financement, ses arbitrages patrimoniaux et sa vision d'investisseur engagé. Découvrez : Son retour d'expérience sur les différences sources de financement dont il a bénéficiéPourquoi il a choisi un industriel comme investisseur et comment gérer la pression de sortie des fonds face à sa vision long terme.Son recours récent à la dette avec Pictet, pour financer le développement et le CapEx sans dilution, et refinancer les infrastructures existantes.Sa stratégie d'investissement 100% depuis son cash-out en 2020 : pourquoi, selon lui, l'investissement “impact” est souvent moins risqué qu'on ne l'imagine et pourquoi il refuse systématiquement d'investir dans la tech "pure".Son accompagnement concret de startups comme FruityCorp. Benjamin Dubois (son fondateur) nous rejoint en fin d'épisode pour partager comment Thibault l'a guidé sur le timing de levée et la structuration financière.Bonne écoute !Pour aller plus loin sur les sujets abordés : Business Angel : guide complet pour investir dans une start-up https://sapians.com/blog/business-angel Le cash-out : définition, fonctionnement et investissement https://sapians.com/blog/cash-out-definition-fonctionnement-avantagesInvestir dans un fonds de dette privée ? Définition et fonctionnement https://sapians.com/blog/focus-dette-priveeLe Carried Interest en Private Equity : Définition, Fonctionnement, Fiscalité & Conseils d'Experts https://sapians.com/blog/carried-interestGestion Passive vs Gestion Active : comment mettre en place sa stratégie d'investissement ? https://sapians.com/blog/gestion-passive-vs-gestion-active-----------------------Attention : Les performances passées ne préjugent pas des performances futures et investir comporte des risques de perte partielle ou totale en capital. Ce contenu est informatif et ne constitue pas un conseil en investissement. Toute décision doit être adaptée à votre situation. Si vous souhaitez bénéficier de conseils personnalisés, veuillez créer votre compte ou prendre rendez-vous avec un conseiller Sapians.SAPIANS - RCS n°919 330 969 - ORIAS n°23003561 en qualité de CIF et COA. Activité de démarchage bancaire et financier.

Beyond The Mask: Innovation & Opportunities For CRNAs
Airway Exchange – Ep. 10 – How the Best CRNA Programs Approach Accreditation with Dr. Angie Mund

Beyond The Mask: Innovation & Opportunities For CRNAs

Play Episode Listen Later Jan 27, 2026 41:12


Accreditation can feel overwhelming, but when done well, it's not a once-every-ten-years scramble. Dr. Angie Mund joins us this week to help reframe accreditation as an ongoing leadership practice that shapes program culture, faculty development, and student outcomes. Drawing on decades of experience as a program director, department chair, and national leader, Dr. Mund explains what's usually true long before a successful COA site visit ever begins.  Here's some of what you'll hear in this episode:

Just Focus
#JUST TIPS - Entrepreneur et succession : adoptez ces réflexes pour protéger famille et entreprise

Just Focus

Play Episode Listen Later Jan 22, 2026 36:17


ℹ️ Retrouvez les informations clés de cet épisode dans un guide condensé sur la succession, à télécharger en PDF : https://sapians.com/guide-successionOn parle beaucoup de création de valeur chez les entrepreneurs. Beaucoup moins de sa transmission. C'est pourtant une étape qui apporte son lot de difficultés : indivision, tensions familiales, trésorerie sous pression, fiscalité...Dans cet épisode de Just Focus, Aurore Perrin reçoit Souleymane-Jean Galadima, cofondateur et CEO de Sapians, pour évoquer avec méthode un sujet aussi intime que stratégique : anticiper la succession quand l'essentiel de son patrimoine est concentré dans l'entreprise.Dans cet épisode, on aborde notamment :Pourquoi l'absence d'anticipation peut déclencher des situations d'indivision et cristalliser des conflits familiaux.Les grands repères sur les droits de succession et l'impact concret sur la continuité d'une société (trésorerie, gouvernance, phase de transition).Le Pacte Dutreil : logique, conditions et intérêt pour transmettre une entreprise familiale sans l'asphyxier.Les leviers de transmission du vivant : donation-partage, donation transgénérationnelle, présents d'usage, et les réflexes de formalisation à connaître.Les outils “pare-chocs” souvent oubliés par les dirigeants : mandat de protection future, mandat à titre posthume, testament, et l'assurance-vie (clause bénéficiaire, avant/après 70 ans, encadrement via pacte adjoint).Bonne écoute ! Des ressources pour approfondir : Transmission d'entreprise : 5 stratégies fiscales à connaître https://sapians.com/blog/transmission-entrepriseIndivision successorale expliquée : fonctionnement, droits des héritiers et risques à anticiper https://sapians.com/blog/fonctionnement-indivisionLe calcul des droits de succession, le guide pour tout comprendre https://sapians.com/blog/calcul-droits-successionComment bien rédiger sa clause bénéficiaire ? (Assurance vie, PER assurance) https://sapians.com/blog/clause-beneficiaireDonation-partage transgénérationnelle : comment transmettre directement à vos petits-enfants ? https://sapians.com/blog/donation-partage-transgenerationnelle-----------------------Attention : Les performances passées ne préjugent pas des performances futures et investir comporte des risques de perte partielle ou totale en capital. Ce contenu est informatif et ne constitue pas un conseil en investissement. Toute décision doit être adaptée à votre situation. Si vous souhaitez bénéficier de conseils personnalisés, veuillez créer votre compte ou prendre rendez-vous avec un conseiller Sapians.SAPIANS - RCS n°919 330 969 - ORIAS n°23003561 en qualité de CIF et COA. Activité de démarchage bancaire et financier.

MSME TALK
MSME Vendor Opportunities with Large FMCG Companies – Part 1

MSME TALK

Play Episode Listen Later Jan 18, 2026 44:53


Episode 59 MSME Vendor Opportunities with Large FMCG Companies – Part 1   Guest: Samrat Sehgal, Global Supply Chain Head , Dabur India    Welcome back to MSME TALK® with Industry Expert. Industry Expert segment brings Industry Expert who discusses on specific topic relevant for MSMEs, Startup to scale up and build long-lasting Businesses.  Why did we do this episode: We created this episode because we were receiving many queries from MSMEs on how to become vendors to large FMCG companies, and what it takes to get selected and scale.  Key Topics Covered :-MSME vendor opportunities in large FMCG supply chains-How MSMEs should approach FMCG companies as vendors-Contract manufacturing: selection criteria + compliance non-negotiables-Vendor onboarding process: audit, trials, timelines-Common MSME mistakes and how to avoid them-Raw material suppliers: gate-openers vs deal-breakers-Quality checks: COA + in-house testing-Packaging opportunities for MSMEs-Innovation + eco-friendly niche packaging  For detail breakup of discussion, check the time stamps. Video Episode is also available on Youtube.  MSMEs & startups are looking for various kinds of supports & upgrade. Are you a Product, Service Provider, Expert, Advisor, Consultant, Mentor for MSMEs/Startups? Reach out to MSME TALK to list your business. Fill the form to help us reach out to you. Hey MSME TALK listeners! Hope you have not missed subscribing to our newsletter for the latest news, blogs, and podcast updates. We don't spam your inbox , hence we have highest rate of letter opening in Industry. Subscribe here for Newsletter. MSME TALK Podcast enters Peak Ranking Chart of 20+ Countries in the Apple Podcast Country Entrepreneurship Category. WhatsApp : Send hi - https://wa.me/918097665085 LinkedIn Facebook Instagram Twitter Website Contact us : connect@msmetalk.comClick to All Social Media , Podcast etc links at one place Please give your rating and reviews on apple podcast or Spotify

Make Time for Success with Dr. Christine Li
Visualization Secrets: A Proven Process for Manifesting Your Dreams with Megan Blacksmith

Make Time for Success with Dr. Christine Li

Play Episode Listen Later Jan 15, 2026 47:52 Transcription Available


Send Dr. Li a text here. Please leave your email address if you would like a reply, thanks.In this inspiring episode of the Make Time for Success podcast, host Dr. Christine Li welcomes back Megan Blacksmith, an NLP expert, speaker, and co-founder of Zesty. Together, they dive deep into visualization and neuro linguistic programming (NLP) as powerful tools for breaking old patterns, manifesting dreams, and achieving lasting inner transformation. Megan Blacksmith shares her story of accidental visualization, practical techniques for rewiring your mindset, and guidance on moving through resistance and limiting beliefs. You'll hear real-world examples and actionable strategies to help you create your ideal future—one that's possible, even if it feels out of reach today. Get ready to discover the secrets to manifesting your dreams with clarity, creativity, and confidence!Timestamps:00:00:00 - 00:02:47: Dr. Christine Li introduces the episode and welcomes Megan Blacksmith, who shares her expertise in NLP.00:02:48 - 00:05:35: Megan Blacksmith discusses her entry into NLP, its impact on her coaching, and how subconscious programming affects results.00:05:36 - 00:14:06: Exploration of how emotional events and hidden beliefs hold people back, including analogies like clutter.00:14:06 - 00:18:27: Discussing discomfort as a sign of growth and the challenges of stepping into a new identity.00:24:33 - 00:32:40: Insights into using visualization for goal achievement, with Megan Blacksmith's personal story as an example.00:32:41 - 00:39:00: Detailed visualization tips: make your vision vivid, specific, and emotionally charged.To sign up for the Waitlist for the Simply Productive Program, go to https://maketimeforsuccesspodcast.com/SPFor more information on the Make Time for Success podcast, visit: https://www.maketimeforsuccesspodcast.comGain Access to Dr. Christine Li's Free Resource Library -- 12 downloadable tools and templates to help you bypass the impulse to procrastinate: https://procrastinationcoach.mykajabi.com/freelibraryTo work with Dr. Li on a weekly basis in her coaching and accountability program, register for The Success Lab here: https://www.procrastinationcoach.com/labConnect with Us!Dr. Christine LiWebsite: https://www.procrastinationcoach.comFacebook Group: https://www.facebook.com/groups/procrastinationcoachInstagram: https://www.instagram.com/procrastinationcoach/TikTok: https://www.tiktok.com/@procrastinationcoachThe Success Lab: https://maketimeforsuccesspodcast.com/lab                       Simply Productive: https://maketimeforsuccesspodcast.com/SPMegan BlacksmithWebsite: http://www.becomingzesty.com/Podcast: http://becomingzesty.com/podcastInstagram: https://instagram.com/becomingzestyYouTube: https://www.youtube.com/@becoming_zesty

Just Focus
#Merci Prosper - Investir dans l'immobilier des seniors sans viager, grâce à la vente partielle - avec Thibault Corvaisier

Just Focus

Play Episode Listen Later Jan 15, 2026 50:47


Et si vous pouviez investir dans l'immobilier tout en redonnant du pouvoir d'achat aux seniors ? En France, 3 600 Mds € sont bloqués dans la pierre, appartenant à 18 millions de seniors.71% des +70 ans sont propriétaires de leur résidence principale. Pourtant, ils sont nombreux à connaître des fins de mois difficiles.Un paradoxe que Merci Prosper entend transformer en solution en bousculant les codes du viager.Dans cet épisode, Aurore Perrin reçoit Thibault Corvaisier, Co-fondateur & Président de Merci Prosper pour présenter leur approche : la vente partielle d'un bien immobilier sous forme du "Contrat Prosper". Un mécanisme peu connu, pensé pour permettre aux seniors de libérer des liquidités sans quitter leur logement, tout en offrant aux investisseurs une exposition immobilière portée par une logique d'impact.Au programme :Vente partielle vs viager : qu'est-ce qui change concrètement ? Thibault détaille la mécanique du Contrat Prosper, et surtout son cœur juridique : l'indivision.Qui sont leurs clients ? Qui peut investir à leurs côtés ? La structuration de leur foncière solidaire agréée ESUS qui réconcilie performance et impact social.Un exemple chiffré pour bien comprendre le mécanisme de vente partielle.Ce qui différencie vraiment un fonds à impact d'un simple placement financier-----------------------Savez-vous vraiment comment fonctionne un société de gestion ? Un fonds d'investissement ? Ce qu'il se passe au-delà des chiffres et des due diligences ?Dans "Focus Fonds", nous explorons ce qu'il se trouve de manière très concrète derrière les investissements des fonds et de leurs investisseurs.-----------------------Quelques ressources pour aller plus loin : Indivision ou SCI familiale ? Guide comparatif pour héritiers (avantages, limites et fiscalité) https://sapians.com/blog/indivision-ou-sci-familialeInvestir dans l'immobilier locatif ou dans un fonds immobilier ? https://sapians.com/blog/investir-dans-immobilier-locatif-ou-dans-fonds-immobilier4 placements immobiliers pour booster les performances de son assurance vie https://sapians.com/blog/4-placements-immobilier-booster-performance-assurance-vie-----------------------Attention : Ceci est une communication publicitaire. Les performances passées ne préjugent pas des performances futures et investir comporte des risques de perte partielle ou totale en capital. Ce contenu est informatif et ne constitue pas un conseil en investissement. Toute décision doit être adaptée à votre situation. Si vous souhaitez bénéficier de conseils personnalisés, veuillez créer votre compte ou prendre rendez-vous avec un conseiller Sapians.SAPIANS - RCS n°919 330 969 - ORIAS n°23003561 en qualité de CIF et COA. Activité de démarchage bancaire et financier.

Cannabis School
Pandemic Punch

Cannabis School

Play Episode Listen Later Jan 13, 2026 25:58


Pandemic Punch is that “turn the volume down on life” strain that still lets your brain stay online. First hit comes in bright and punchy, fruit and citrus up front, then it slides into a calm, floaty body ease that makes your shoulders drop without instantly stapling you to the couch. The vibe is happy, relaxed, and a little giggly, with a steady “I'm good” headspace.Smell and taste lean fruity-citrus with a skunky tang underneath, like sweet punch with a funky edge. It's the kind of profile that feels fun on the inhale, then settles into that mellow exhale where your body remembers it can unclench.Cannabinoids: THCA 26.291%, Total THC 23.269%, Total cannabinoids 27.137%, CBGA 0.561%, CBC 0.0739%, Δ9-THC 0.2115%, CBD and most minors ND.  Terpenes: β-Caryophyllene 0.689%, D-Limonene 0.352%, Linalool 0.342%, β-Myrcene 0.231%, α-Humulene 0.148%, everything else listed ND in this COA.  Best for: decompressing, pain-tension days, evening wind-down, and laughing at stuff that is not even that funny.Save on Dr Dabber with Code: Cannabisschool10Save on Storz & Bickel with Code : CannabisschoolSave on Santa Cruz Shredder with Code: CSP10Save on Bomb Erigs with Code: CSPScore 100 on your test

pandemic drop cbd smell punch thc cbc coa bickel storz dabber linalool cbga myrcene
Just Focus
#JUST TIPS - Remploi du produit de cession : les pires erreurs des entrepreneurs (et comment les éviter)

Just Focus

Play Episode Listen Later Jan 8, 2026 25:58


L'apport-cession et le remploi du produit de vente : un avantage fiscal souvent perçu comme automatique après la vente d'une entreprise. Mais ce mécanisme est-il vraiment adapté à tous les entrepreneurs ?Dans cet épisode, nous recevons Rémi Douchet, co-fondateur d'iVesta et de Sapians, deux family offices qui accompagnent des entrepreneurs sur leurs stratégies patrimoniales post-cession.Fort de son expérience auprès d'une centaine d'entrepreneurs, Rémi partage un constat surprenant : beaucoup regrettent d'avoir choisi le remploi par défaut, contraints de faire des investissements qu'ils n'auraient jamais faits autrement.Vous découvrirez :Les contraintes méconnues du dispositif 150-0 B ter et pourquoi il n'est pas toujours pertinentLe piège du timing : concilier earn-out et obligations de réinvestissement en seulement 2 ansBusiness angel et remploi : pourquoi peu d'entrepreneurs s'enrichissent réellement avec ces investissementsLes vrais critères pour savoir si le remploi correspond à votre situation patrimonialeComment éviter les décisions fiscales qui deviennent de mauvaises décisions patrimonialesBonne écoute ! Des ressources pour approfondir : Téléchargez la fiche récapitulative de Sapians sur l'apport-cession https://sapians.com/guide-apport-cessionQuels experts solliciter pour préparer mon apport-cession puis son réinvestissement en 150-0 b ter ? https://sapians.com/blog/quels-experts-solliciter-pour-reussir-apport-cessionQuelle allocation idéale en fonds 150-0 b ter et comment bien les sélectionner ? https://sapians.com/blog/fonds-150-0-b-terComprendre l'abus de droit en apport-cession : Sanctions, exemples... https://sapians.com/blog/apport-cession-abus-de-droitQuels sont les avantages et les inconvénients d'un apport-cession ? https://sapians.com/blog/apport-cession-avantages-et-inconvenients-----------------------Attention : Les performances passées ne préjugent pas des performances futures et investir comporte des risques de perte partielle ou totale en capital. Ce contenu est informatif et ne constitue pas un conseil en investissement. Toute décision doit être adaptée à votre situation. Si vous souhaitez bénéficier de conseils personnalisés, veuillez créer votre compte ou prendre rendez-vous avec un conseiller Sapians.SAPIANS - RCS n°919 330 969 - ORIAS n°23003561 en qualité de CIF et COA. Activité de démarchage bancaire et financier.

Murder Sheet
The Cheat Sheet: Victims and Voir Dire

Murder Sheet

Play Episode Listen Later Jan 2, 2026 52:29


The Cheat Sheet is The Murder Sheet's segment breaking down weekly news and updates in some of the murder cases we cover. In this episode, we'll talk about cases from New Hampshire, New Jersey, Colorado, and Mississippi.NBC Boston's coverage of the murder of Judy Lord: https://www.nbcboston.com/news/local/nh-cold-case-unit-to-announce-significant-development-in-decades-old-case/3850076/CBS News's report on developments about Nazeer Hameed's involvement in the murders of Sasikala Narra and her son Anish Narra: https://www.cbsnews.com/philadelphia/news/sasikala-and-anish-narra-maple-shade-nj-cold-case/We also accessed news articles from the Concord Monitor, the Trenton Times, and the South Jersey Times via Newspapers.com.The ruling from the Colorado Court of Appeals on public access issues in the Edward R. Sandoval case about the murder of Dennis Lozoya: https://gazetteedit.wpenginepowered.com/wp-content/uploads/2025/11/22CA0824-Peo-v-Sandoval-10-30-25.pdfThe appeal filed in the case of William Ervin Edwards in the murder case of Robert Davis: https://courts.ms.gov/appellatecourts/docket/sendPDF.php?f=web0001.COA.2025-KA-138.118328.0.pdf&c=99062&a=N&s=2Find discounts for Murder Sheet listeners here: https://murdersheetpodcast.com/discountsCheck out our upcoming book events and get links to buy tickets here: https://murdersheetpodcast.com/eventsOrder our book on Delphi here: https://bookshop.org/p/books/shadow-of-the-bridge-the-delphi-murders-and-the-dark-side-of-the-american-heartland-aine-cain/21866881?ean=9781639369232Or here: https://www.simonandschuster.com/books/Shadow-of-the-Bridge/Aine-Cain/9781639369232Or here: https://www.amazon.com/Shadow-Bridge-Murders-American-Heartland/dp/1639369236Join our Patreon here! https://www.patreon.com/c/murdersheetSupport The Murder Sheet by buying a t-shirt here: https://www.murdersheetshop.com/Check out more inclusive sizing and t-shirt and merchandising options here: https://themurdersheet.dashery.com/Send tips to murdersheet@gmail.com.The Murder Sheet is a production of Mystery Sheet LLC.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

The Crucible - The JRTC Experience Podcast
122 S13 Ep 07 - The Backbone in Action: Unleashing Non-Commissioned Officer Power at Echelon w/the JRTC Senior NCOs

The Crucible - The JRTC Experience Podcast

Play Episode Listen Later Dec 31, 2025 34:43


The Joint Readiness Training Center is pleased to present the one-hundredth-and-twenty-second episode to air on ‘The Crucible - The JRTC Experience.' Hosted by MAJ Marc Howle, the Brigade Senior Engineer / Protection Observer-Coach-Trainer, and MAJ David Pfaltzgraff, BDE XO OCT (formerly the BDE S-3 Operations OCT), from Brigade Command & Control (BDE HQ) on behalf of the Commander of Ops Group (COG). Today's guests are senior non-commissioned officers of JRTC: MSG Jared Cawthon, MSG Randell Conway, and SFC Corey Rinn. MSG Cawthon is the BDE Fires Support NCOIC and MSG Conway is the BDE Intelligence NCOIC OCT in Brigade Command & Control (BDE HQ). SFC Rinn is the Explosive Ordinance Disposal Senior OCT for TF-5 (BDE Engineer BN).   This episode focuses on leadership through the deliberate and effective utilization of Noncommissioned Officers at echelon, emphasizing that success in LSCO is fundamentally leader business, not officer business versus NCO business. A central theme is the NCO's role in identifying and mitigating friction before it manifests in execution. Drawing on repeated JRTC observations, the discussion highlights how experienced NCOs sharpen plans through rehearsals, checklists, and anticipation of second- and third-order effects—time, distance, sustainment, displacement, and execution risk—that are often missed in rushed or staff-centric planning. When NCOs are fully integrated into MDMP, mission analysis, COA development, and rehearsals, staffs are more synchronized, plans are more executable, and formations adapt faster once friction is encountered.    The episode also addresses persistent gaps in how formations employ NCOs, particularly on staffs. Too often, senior NCOs are relegated to security or administrative tasks instead of being empowered contributors to planning, targeting, and cross–warfighting function integration. The panel underscores disciplined initiative, delegation of authority, and clear roles and responsibilities as decisive leadership practices that unlock NCO potential. Effective formations deliberately train NCOs to operate confidently in planning environments, leverage their experience to challenge assumptions, and serve as connective tissue between operations, intelligence, fires, sustainment, and protection. The consistent takeaway is clear: units that empower NCOs as planners, synchronizers, and leaders—not just executors—operate with less friction, greater cohesion, and higher combat effectiveness in the hardest fights.    Part of S13 “Hip Pocket Training” series.   For additional information and insights from this episode, please check-out our Instagram page @the_jrtc_crucible_podcast   Be sure to follow us on social media to keep up with the latest warfighting TTPs learned through the crucible that is the Joint Readiness Training Center.   Follow us by going to: https://linktr.ee/jrtc and then selecting your preferred podcast format.   Again, we'd like to thank our guests for participating. Don't forget to like, subscribe, and review us wherever you listen or watch your podcasts — and be sure to stay tuned for more in the near future.   “The Crucible – The JRTC Experience” is a product of the Joint Readiness Training Center.

Let's talk about Horror
Spezial mit Marcus: Coming of Age - mit Anja

Let's talk about Horror

Play Episode Listen Later Dec 30, 2025 74:43


Nachdem Marcus in den bisherigen Folgen stets Gäste hatte, zu denen er eine Verbindung durch Metal hatte, treffen wir diesmal auf eine alte Bekannte: Anja wollte schon immer mal über das Thema "Coming Of Age" sprechen. Im Ursprung war angedacht, dies als "Offtopic-Special" im Rahmen von Marcus' eigenem Podcast zu machen, doch mit der neuen Situation haben sich andere Möglichkeiten ergeben. Anja und Marcus haben jeweils zwei Filme und eine Serie im Gepäck, die sich mit dem Thema beschäftigen. Zuvor gilt es jedoch zu klären: Was versteht man überhaupt unter COA? Handelt es sich hierbei um ein "echtes" Film-Genre oder doch eher um einen Überbegriff? Seid also gespannt, was die beiden mitbringen und wieso sie der Auffassung sind, dass es sich hierbei um Vertreter handelt, die man zum COA zählen kann. Nach spaßigem Beginn entwickelt sich die Unterhaltung nicht selten auch in eine nachdenkliche Richtung, schließlich wissen wir alle, dass Erwachsenwerden nicht immer nur mit Spaß sondern oft auch mit Enttäuschungen und Herausforderungen verbunden ist. Besuche www.horrortalk.de und erfahre, wie du dabei sein kannst. Unterstütze den Podcast mit einer Bewertung und einem Kommentar – damit hilfst Du mir, dass noch mehr Horrorfans den Weg zu uns finden. Vielen Dank :) „Let's Talk About Horror“ – nicht nur zuhören, sondern mitmachen!

This Is Woman's Work with Nicole Kalil
Emotional Fitness for Real Life with Dr. Emily Anhalt | 371

This Is Woman's Work with Nicole Kalil

Play Episode Listen Later Dec 17, 2025 37:33


Friend, we obsess over steps, macros, and workout streaks… but when was the last time you checked in on your emotional fitness? In this episode, Nicole sits down with clinical psychologist, emotional fitness expert, and Coa co-founder Dr. Emily Anhalt to talk about what it actually looks like to “train your brain” — no toxic positivity, no “just meditate more,” and definitely no pretending everything's fine when it's very much not.  Emily breaks down her 7 traits of emotional fitness (think mindfulness, curiosity, boundaries, resilience, empathy, communication, and play) and how to build them like muscles over time — one emotional push-up at a time. We get into why empathy without boundaries will burn you all the way out, how to ask for feedback without spiraling into defensiveness, and why trusting your future self might be the most confidence-building thing you do this year.  If you've ever felt resentful because you said “yes” when every cell in your body wanted to say “no,” if you're tired of carrying everyone else's emotions like luggage, or if anxiety and uncertainty have been driving the bus lately, this one's for you. Emotional fitness won't stop life from throwing heavy shit your way — but it will make you strong enough to carry it, move it, and eventually put it down. We explore: What emotional fitness actually means (and how it's different from “fixing yourself”) The 7 traits of emotional fitness — and why you don't have to master all of them at once How to spot the cost of avoiding discomfort (hello, resentment and burnout)The “emotional push-up” exercise you can start doing today How to hold empathy and boundaries so caring for others doesn't drain you dry The best advice Emily ever got for dealing with anxiety and uncertainty Why trusting your future self is a deeply confident way to live Because when you trust your future self, you stop living in panic about what might happen and start living with confidence in who you're becoming — and that shifts everything.  Thank you to our sponsors! Get 20% off your first order at curehydration.com/WOMANSWORK with code WOMANSWORK — and if you get a post-purchase survey, mention you heard about Cure here to help support the show!  Sex is a skill. Beducated is where you learn it. Visit https://beducate.me/pd2550-womanswork and use code womanswork for 50% off the annual pass. Connect with Emily: Website: https://www.dremilyanhalt.com/ Book: https://a.co/d/couFOLN IG: https://www.instagram.com/dremilyanhalt/ X: https://x.com/dremilyanhalt LI: https://www.linkedin.com/in/dremilyanhalt/ Related Podcast Episodes Your Brain Is a Filthy Liar with Bizzie Gold | 361 How To Play: Shift Your Thinking, Inspire Connection & Spark Creativity with Cas Holman | 355 144 / Jay & Nicole Kalil on Partnership, With Guest Host Lynn Casaletto Share the Love: If you found this episode insightful, please share it with a friend, tag us on social media, and leave a review on your favorite podcast platform!

Ortho Insider
Drs. Mark Bowditch & Len Marais - Season 3, Episode 5

Ortho Insider

Play Episode Listen Later Dec 7, 2025 40:47


In this episode of the COA's Ortho Insider Podcast, host Dr. Adrian Huang welcomes Dr. Mark Bowditch and Dr. Len Marais, Past Presidents of the British Orthopaedic Association (BOA) and the South African Orthopaedic Association (SAOA). Together, they explore the contrasts and commonalities within their healthcare systems, discuss approaches to surgical training, and share rich insights on orthopaedic education and care delivery across their regions. Their conversation highlights the value of global collaboration and the lessons that emerge when leaders exchange perspectives. Don't miss this thoughtful dialogue with two influential voices shaping orthopaedic practice around the world.

Good Work with Barrett Brooks
The Hidden Grief Behind High Achievement with Emily Anhalt

Good Work with Barrett Brooks

Play Episode Listen Later Nov 20, 2025 96:28


This week, I talk with Dr. Emily Anhalt—a clinical psychologist, founder, and writer who's spent the past 15 years exploring what it really means to be emotionally healthy. You might know her from her TED Talk or her work at Coa, but in this conversation, we go deeper. We talk about growing up in Silicon Valley, the pressure of being a high-achieving kid, and why so many successful people still carry unresolved grief. Emily shares how ADHD shaped her early life, what led her to leave pre-med for psychology, and how emotional patterns from childhood often resurface in our work and relationships. We also dive into what actually makes therapy effective and why hitting your goals doesn't always bring peace. If you've ever built something meaningful but still felt unsettled, or questioned what's really driving your ambition, I think this episode will speak to you. Let's get to it. In this episode: (00:00) - Intro (02:52) - How a beanbag chair and snacks helped Emily unlock her best work (08:01) - Growing up inside the Silicon Valley success machine (09:45) - Why high performers need a different kind of therapy  (11:53) - The story of Emily's parents and how they ended up in the Valley (13:54) - Reframing ADHD as a strength, not a stigma (16:33) - The early experiences that shaped Emily's emotional lens (23:40) - How Emily chose psychology—and what kept her going (28:40) - The moment therapy stopped being about symptoms (33:06) - Why grief is a necessary companion to growth (38:21) - The origin story of a company built around emotional fitness (42:30) - What changes when you go from therapist to founder (45:27) - The qualities of high-integrity therapy (51:26) - How Emily knew it was time to write a book (58:20) - What really keeps entrepreneurs stuck—and how to get unstuck (01:02:09) - What it feels like when success leaves you empty (01:05:32) - How to rebuild when your goals stop making sense (01:07:44) - Why achieving meaning isn't the same as feeling it (01:11:06) - Why therapy often gets harder before it gets better (01:12:47) - Abandoning hard feelings before healing happens (01:13:40) - The isolation of success—and how to find support (01:21:17) - How overachievers get trapped in burnout (01:29:26) - Healthy ways to process anger (01:33:46) - What makes Emily world-class? (01:34:09) - Emily's most beautiful future (01:34:49) - Who Emily is becoming Get full show notes and links at https://GoodWorkShow.com.Watch the episode on YouTube: https://www.youtube.com/@barrettabrooks.

Cleve Gaddis Real Estate Radio Show
HOA vs COA: What Really Changes for Homeowners? Practical Insights with Michael Crew

Cleve Gaddis Real Estate Radio Show

Play Episode Listen Later Nov 17, 2025 12:00


Welcome to Go Gaddis Real Estate Radio! I'm Cleve Gaddis, here to make real estate clear, simple, and worry-free so you can buy and sell with complete confidence and without the stress or second-guessing that often comes with life's biggest investments. Today, we continue our conversation with Michael Crew, CEO of Homeowner Management Services, Inc., to talk about the practical side of community governance. Whether you're in an HOA or a COA, the legal structure of your community affects what you own, what you're responsible for, and how your property is protected. Using insights from the attached script, “Making It Legal — and Protecting Your Property,” we break down: What everyday responsibilities change depending on whether you're in an HOA or COA How maintenance, repairs, reserves, and assessments are handled differently What homeowners must legally maintain vs. what the association maintains How insurance coverage changes — and the expensive surprises homeowners can avoid Why understanding your governing documents protects your property value What rights homeowners gain or lose depending on the structure of their community Most importantly, we'll explain why legal clarity matters — and how knowing the structure of your community can save you time, money, and frustration. Plus, I'll share details about our Upside Program, designed to give sellers all the options they need to make smart, informed decisions. If you have a question, want to challenge something you hear, or want us to feature your neighborhood, visit GoGaddisRadio.com to connect or subscribe.

Cleve Gaddis Real Estate Radio Show
Can a COA Become an HOA? Understanding the Real Difference with Expert Michael Crew

Cleve Gaddis Real Estate Radio Show

Play Episode Listen Later Nov 17, 2025 12:00


Welcome to Go Gaddis Real Estate Radio! I'm Cleve Gaddis—here to make real estate clear, simple, and worry-free. Today we're tackling a question that confuses homeowners, buyers, and even some agents: Can a COA become an HOA? And what's the real difference between the two? Joining me is Michael Crew, CEO of Homeowner Management Services, Inc., one of Atlanta's most trusted experts in community association management. We'll break down: What separates a Condominium Owners Association (COA) from a Homeowners Association (HOA) Why the appearance of a community can be misleading—townhomes can be condos, and detached homes can be part of a COA Whether a COA can ever “convert” into an HOA (and why it's far more complicated than most people think) How a community's legal documents—not the architecture—determine its ownership structure What buyers and sellers must review before making decisions, including the Declaration of Condominium and the property's legal description How an experienced agent can help you locate, interpret, and understand these documents before you sign anything We'll also share insights from “The Neighborhood That Wanted a Do-Over,” a real-world example of what happens when a community discovers they're operating under the wrong governance structure—and what it takes to fix it. Plus, I'll tell you more about our Upside program, built to give buyers and sellers all the tools and options they need to move forward with confidence. Got a question, comment, or challenge? Visit GoGaddisRadio.com to connect, push back, or subscribe so you never miss an episode.

Living Well with Liv Hill
Living Well Podcast - LHN Coach Chat - Answering All the Tough Questions

Living Well with Liv Hill

Play Episode Listen Later Nov 15, 2025 37:47


In this episode of the Living Well podcast, host Liv Hill leads a coaching roundtable with several coaches discussing various health and wellness topics. They address how to maintain health when a spouse isn't supportive, the challenges of menopause, the importance of mindset in overcoming obstacles, and strategies for dealing with setbacks in health journeys. The conversation emphasizes the significance of leading by example, finding joy in personal health journeys, and the necessity of strength training and nutrition, especially during menopause. In this episode, the hosts discuss the importance of adjusting one's approach to fitness and nutrition in the face of setbacks, emphasizing the emotional aspects of health journeys. They explore the fluid nature of macronutrients and the pitfalls of influencer diets, advocating for personalized coaching. The conversation also highlights practical strategies for managing family meals without compromising individual health goals.

SUPERFREQ™️
Ep. 115: "The Truth About Location, Belonging, and the Frequency of Place"

SUPERFREQ™️

Play Episode Listen Later Nov 9, 2025 46:03


Key Topics Covered:What gridlines actually doEarth's energetic nervous systemGridlines as frequency transmitters, memory holders, and field mirrorsWhy you're drawn to certain placesMemory completionSignal amplificationTrauma pattern magnetizationArchetypal field recognitionWhy astrocartographic lines may not “feel good”Activation ≠ resonanceField incoherence, premature arrival, or bypass patternsDistortion through unresolved nervous system codingWhat it means to transcend gridlinesFrom memory loop to field stabilityBehavior and perception shifts when the line no longer organizes your fieldThe deeper paradox of place, identity, and safetyBelonging vs becomingSettling vs expandingMovement as control vs contactKey Questions Explored:Where was I when I first felt safe in my body? Is that memory tied to a place—or a presence?What are the somatic cues of safety when there's no cognitive memory?What am I postponing by not allowing myself to belong somewhere?Is my constant movement about expansion—or avoidance of collapse?If I could feel safe in my own field, would the question of “place” still matter?Does astrology and numerology actually affect people?--------Follow @whoistaliyah // @superfreq.coA high vibe podcast ya'll exploring all things Frequencies— How they govern form, shape our realities, and are the key to living from your full potential. It's non-woo convos about super woo shit—Unpacking what I call the “Science of Self” From body and soul literacy to the power of understanding vibration, higher consciousness, quantum physics and spiritual psych, let this podcast become a resource for you on your journey to self-mastery. If you're curious and ready to free your mind, unlock the body and, become limitless then you're in the right place. I'm your host Talie and this is SuperFreq—awakening for the next gen. Stay Curious, Question Everything

NASFAA's Off the Cuff Podcast
OTC AskRegs Experts: Unpacking Cost of Attendance

NASFAA's Off the Cuff Podcast

Play Episode Listen Later Oct 30, 2025 34:09


This week on "Off the Cuff," Tim and David do a deep dive into the cost of attendance (COA). David begins the conversation by discussing the purpose of COA, and its different categories. From there, Tim and David discuss multiple aspects of COA, including how institutions build their COA and additional fees – such as health insurance and student loan fees. The team also details resources and provides examples to help members better understand COA, including AskRegs answers and an upcoming NASFAA U course dedicated to the topic. 

Spivey Consulting Law School Admissions Podcast
Financial Aid & Student Loans After the "Big Beautiful Bill," with Sydney Montgomery & Kristin Shea

Spivey Consulting Law School Admissions Podcast

Play Episode Listen Later Oct 28, 2025 47:39


In this episode of Status Check with Spivey, Spivey consultant and former admissions dean Nikki Laubenstein discusses the financial aid and student loan considerations that prospective law students should be thinking about post-"Big Beautiful Bill," joined by Sydney Montgomery, who is the Executive Director & Founder of Barrier Breakers, and Kristin Shea, who has led the law school financial aid office at Syracuse University for almost a decade as a part of a 20-year career in legal education.Nikki, Sydney, and Kristen talk about the changes to student loans and student loan caps resulting from the One Big Beautiful Bill Act (9:43), the changes to repayment plans (35:58), who those changes apply to (5:21), the differences between undergraduate financial aid/scholarships and law school financial aid/scholarships (20:52), understanding tuition vs. total cost of attendance and how that relates to scholarship reconsideration and student loan caps (24:17), possible ways schools could help fill the gap especially for students targeting public interest jobs (38:21), advice for those planning to work while in law school (41:00), why prospective law students should start thinking about financial aid earlier on in the admissions process than most do (30:47), and more.Barrier Breakers is a nonprofit that has worked with 7,000+ first-generation and other marginalized students on the college and law school application process. Sydney Montgomery, the daughter of a Jamaican immigrant mother and military parents, was the first person from her high school to go to Princeton University and then later Harvard Law School. She has dedicated her life and career to supporting first-generation students and has a particular passion for financial aid. She is a member of the Forbes Nonprofit Council and has been featured in Inc., Forbes, FastCompany, Medium, CNBC, and others. Kristin Shea is a higher education professional with twenty years of experience, including law school enrollment management, recruitment, and financial aid; alumni, donor, and employer relations; and marketing and communications. The last decade of her career has been dedicated to financial aid, and she is passionate about helping law students make smart, thoughtful financial plans for their education. She holds a bachelor's degree in biology and psychology and an MBA from Le Moyne College.We hope to do a follow-up episode in the spring with more information on how law schools are addressing these changes. We also encourage you to reach out to the financial aid offices of schools you're considering once admitted to learn about any programs they may offer and any assistance they can provide. As Kristin says in this episode, "The map may have some alternative directions, but you can still reach your destination, and there are many people who want to help." We have also linked a number of financial aid resources below.Federal Student Aid:FAFSA® Application | Federal Student Aid – 2026-27 FAFSA available noOne Big Beautiful Bill Act Updates | Federal Student AidRepaying Student Loans 101 | Federal Student AidWhat does cost of attendance (COA) mean? | Federal Student Aid AccessLex Institute Resources:Student Loan Calculator | AccessLexStudent Aid Policy and Action Center | AccessLexPaying for Law School | AccessLexGuide to Private Student Loans | AccessLexScholarship Databank | AccessLex – includes more than 800 law scholarship and writing competitions (totaling more than $3M).Free Credit Report:Annual Credit Report.com - Home PageEqual Justice Works – LRAP FAQImportant Questions to Ask About Any LRAP  - Equal Justice Works--You can listen and subscribe to Status Check with Spivey on ⁠⁠Apple Podcasts⁠⁠, ⁠⁠Spotify⁠⁠, and ⁠⁠YouTube⁠⁠. You can read a full transcript (with timestamps) here.

The Successful Chiro
How to Build a World-Class Community Outreach Assistant (COA) System to End the New Patient Rollercoaster

The Successful Chiro

Play Episode Listen Later Oct 22, 2025 16:46


In this episode, you'll learn:Why the “new patient volume rollercoaster” happens—and how to stop itWhat makes the COA role a must-have in every growth-focused clinicThe biggest hiring and management mistakes (and how to avoid them)The exact KPIs and accountability systems that drive consistent new patient flowProven call metrics from top COAs (8–12 hours/week, 1,200+ calls/month!)How to build the culture, systems, and communication loops that keep your outreach thrivingNext Steps:

The Metabolic Classroom
Ketogenesis & Stress: Can Stress Hormones Actually Be Good For You?

The Metabolic Classroom

Play Episode Listen Later Oct 15, 2025 20:40


visit: https://www.benbikman.comvisit: https://insuliniq.com In this Metabolic Classroom lecture, Dr. Bikman explores the deep biochemical relationship between stress and ketone production, uncovering how the body interprets stress signals as cues to mobilize fat and create ketones.He explains how stress hormones—like epinephrine, cortisol, glucagon, and growth hormone—aren't just emergency signals but actually metabolic adaptation hormones that help the body shift into fat-burning mode. Through the sympathetic nervous system and hormone cascades, the body responds to stress by increasing lipolysis and triggering ketogenesis, even during fasting, exercise, or low-carb eating.Ben walks through how ketogenesis begins at the level of fat cells and liver mitochondria, and how key molecules like acetyl-CoA and oxaloacetate determine whether the body makes glucose or ketones.Importantly, he clarifies that while stress can trigger positive metabolic shifts, chronic stress without relief can lead to harmful insulin resistance. The takeaway: understanding the difference between acute and chronic stress is key to using this response to your metabolic advantage. Hosted on Acast. See acast.com/privacy for more information.

De Dag
#1966 - Angst onder asielzoekers na rellen en protesten

De Dag

Play Episode Listen Later Oct 3, 2025 20:08


Veel asielzoekers voelen zich onveilig sinds de rechtsextremistische rellen in Den Haag, een dreigende bestorming van een azc in Den Bosch en de soms grimmige protesten bij asielzoekerscentra van de afgelopen weken. In deze podcast bezoekt Elisabeth de 46-jarige Yousef uit Syrie, die op een azc in Winterswijk woont, en de 25-jarige Irakees Dawood in Arnhem.  De angst is groot, vertelt Yousef. Bewoners van het azc durven niet meer alleen het centrum van Winterswijk in uit angst voor problemen. Hij is bang om in elkaar geslagen te worden of erger: gedood. Ook Dawood herkent die gevoelens, onder asielzoekers wordt er veel over gesproken. In een enquête van vluchtelingenwerk zei 70% van de respondenten bang of heel bang te zijn.  Het COA zegt in een reactie dat de protesten zich veelal richten op nieuwe azc's. De ervaring van het COA is dat de weerstand sterk afneemt als een azc er langer is en de opvang goed gaat. Als er zorgen over de veiligheid zijn is er beveiliging op COA-locaties, voorlichting voor azc-bewoners en zijn er vertrouwenspersonen. Reageren? Mail dedag@nos.nl Presentatie: Elisabeth Steinz Montage: Marco Geijtenbeek Redactie: Ulrike Nagel en Judith van de Hulsbeek

Johnny's House
FULL SHOW: Live in Cape Canaveral

Johnny's House

Play Episode Listen Later Sep 18, 2025 86:56


We are LIVE from Hyatt Place in Cape Canaveral before our Johnny's House cruise sets sail! Some of the cruisers are going on their first cruise and we hear from people who have traveled from Arizona to be with us! We had the BEST dinner at Coa last night ... when did you have the best meal! See omnystudio.com/listener for privacy information.

Johnny's House
FULL SHOW: Live in Cape Canaveral

Johnny's House

Play Episode Listen Later Sep 18, 2025 86:56


We are LIVE from Hyatt Place in Cape Canaveral before our Johnny's House cruise sets sail! Some of the cruisers are going on their first cruise and we hear from people who have traveled from Arizona to be with us! We had the BEST dinner at Coa last night ... when did you have the best meal! See omnystudio.com/listener for privacy information.

Consuming the Craft
Food Safety Modernization Act and the Rise of Regulated Edibles with Chris Reedy of NC BioNetwork

Consuming the Craft

Play Episode Listen Later Sep 17, 2025 40:19


 Today on Consuming the Craft, I welcomed Chris Reedy, Senior Director of Food, Beverage, and Natural Products Industry Training at the Natural Products Laboratory and Test Kitchen of NC BioNetwork. We dove deep into the rapidly evolving food safety landscape, particularly focusing on the Food Safety Modernization Act (FSMA) 204 and its sweeping impact on food and beverage traceability. Our conversation ranged from the intricate logistics of tracking every ingredient in a sandwich to the challenges faced by beverage producers, natural product makers, and those entering the world of CBD and THC-infused products. We didn't shy away from discussing the regulatory Wild West these days, the importance of good manufacturing practices, and what's coming down the pike for craft producers as federal scrutiny ramps up. Chris Reedy brings decades of expertise in the intersection of food, beverage, natural products, and industry training. As the mind behind NC BioNetwork's laboratory and test kitchen, he has helped countless producers, from breweries to natural supplement startups, navigate regulations, quality control, and product development. His insights stem from both a scientific and a practical industry perspective, ensuring that companies strike a balance between innovation and safety and compliance. Chris is a passionate advocate for proactive quality management and is intimately familiar with both the promise and pitfalls of rapidly expanding product categories, such as CBD, THC, and functional foods. “I hope these companies that are making these products are going to start acting  like food and beverage companies.” ~Chris Reedy Today on Consuming the Craft: ·     FSMA 204 requirements will soon compel all food supply chain businesses to maintain thorough traceability records for every ingredient, ingredient source, and lot, greatly improving speed and accuracy in foodborne illness recalls.·     Transportation and logistics—especially temperature and sanitation in refrigerated trucking, remain a huge compliance challenge and could become a pain point as regulations tighten.·     Even small producers, like sandwich makers and brewers, must adopt lot coding and traceability, associating each output with precise ingredient origins.·     THC and CBD-infused foods, beverages, and supplements are currently in regulatory limbo, with the FDA focusing initial enforcement mainly on products that pose a risk to children or appear as copycats of popular snacks.·     Many CBD and THC product makers fail basic quality assurance: lack of testing, unclear dosing on packaging, and no third-party certification, all of which can cause dangerous dosing errors.·     Field-to-shelf testing for compounds like THC in hemp products requires a DEA-registered lab, making comprehensive quality assurance both expensive and complex for startups.·     State and federal agencies lack the manpower to inspect and enforce these new standards fully, so proactive internal quality systems and involving health officials early are recommended.·     Training, workforce development, and support from entities like NC BioNetwork can help companies establish robust quality management systems and prepare for both current and coming inspections. Contact Chris Reedy: NC BioNetwork – https://ncbionetwork.org/ Resources Mentioned: NC BioNetwork Laboratory & Industry Training: Food, beverage, and natural products services, COA assistance, and product testing information.FSMA (Food Safety Modernization Act) 204 – details on new federal traceability requirements.Multi-parameter Beer Testing (Anton Paar) – available free for every NC brewery, up to six samples per month.The Dietary Supplement Health and Education Act (DSHEA) – framework for supplement industry regulation.For more information about industry training, regulatory readiness, and laboratory services, reach out to Chris and the team at NC BioNetwork. Whether you're brewing, blending, compounding, or innovating in the natural product space, their support can help you meet quality standards and stay ahead of federal regulations. This episode is brought to you by… McConnell Farms - Taste the Way You Remember. Enjoy homemade ciders and ice cream made from only the best produce on the market. Visit the McConnell Farms website to learn more about our seasonal inventory and the delicious creations you can make with our homegrown produce. Consuming the Craft Thanks for tuning into this week's Consuming the Craft Podcast episode, brought to you by AB Tech's Craft Beverage Institute of the Southeast. If you enjoyed this episode, please subscribe and leave a review wherever you get your podcasts. Apple Podcasts | GooglePlay  Be sure to share your favorite episodes on social media to help us reach more craft beverage enthusiasts. To learn more about AB Tech and the Craft Beer Institute of the Southeast, visit our website. 

The Retirement Wisdom Podcast
Strengthen Your Emotional Fitness – Dr. Emily Anhalt

The Retirement Wisdom Podcast

Play Episode Listen Later Sep 1, 2025 25:31


Do you know what you'll be retiring to? Join us for six Fridays starting on October 3rd and invest in Future You. Learn more here. ___________________________ How much time do you spend working out your body versus working out your emotional health? Physical fitness requires daily practice—hitting the gym once won't deliver the results you want. But when it comes to our emotions, we often think we'll "deal with that later" or assume we don't need to actively work on our emotional well-being. Emily Anhalt, clinical psychologist and author of Flex Your Feelings: Train Your Brain to Develop the 7 Traits of Emotional Fitness, knows this approach doesn't work. She's developed a framework for "emotional fitness"—an ongoing, proactive practice of strengthening your mental and emotional health through small, consistent habits that build resilience, curiosity, and communication skills before you need them. In this conversation, Emily shares how emotionally fit people approach life differently, why playfulness is a valuable health practice (with research to back it up), and practical strategies you can implement today. Her insights are particularly valuable and timely for those navigating retirement transitions, when stress doesn't disappear—it simply changes form. Emily Anhalt joins us from California. _______________________________ We Discuss Why emotional fitness requires daily practice, just like physical fitness How curiosity transforms defensiveness into opportunities for growth Why playfulness can increase creativity, collaboration, and longevity The hidden stress of retirement: identity, relationships, and meaning Setting boundaries: every "yes" is also a "no" to something else The power of "Relationship Retros" for proactive connection Using emojis strategically to improve communication and reduce misunderstandings Building new friendships through your existing network The monthly feedback message that can transform your relationships _______________________ Bio Dr. Emily Anhalt is the author of  Flex Your Feelings: Train Your Brain to Develop the 7 Traits of Emotional Fitness. She is a clinical psychologist, author, and cofounder of Coa, the gym for mental health. For the past fifteen years, Dr. Anhalt has worked clinically with executives, founders, and tech employees, and has conducted extensive research with prominent psychologists and entrepreneurs about how leaders can improve their emotional health. Dr. Anhalt has collaborated with companies like Google, Salesforce, NBCUniversal, NASDAQ, and the NBA. _____________________ For More on Dr. Emily Anhalt Flex Your Feelings: Train Your Brain to Develop the 7 Traits of Emotional Fitness Website ____________________ Podcast Conversations You May Like Ditch Your Baggage – Dr. Bob Rosen Retire Happy – Dr. Catherine Sanderson The Emotionally Intelligent Retirement – Kate Schroeder & Nick Wignall _____________________ About The Retirement Wisdom Podcast There are many podcasts on retirement, often hosted by financial advisors with their own financial motives, that cover the money side of the street. This podcast is different. You'll get smarter about the investment decisions you'll make about the most important asset you'll have in retirement: your time. About Retirement Wisdom I help people who are retiring, but aren't quite done yet, discover what's next and build their custom version of their next life. A meaningful retirement doesn't just happen by accident. Schedule a call today to discuss how the Designing Your Life process created by Bill Burnett & Dave Evans can help you make your life in retirement a great one — on your own terms. About Your Podcast Host Joe Casey is an executive coach who helps people design their next life after their primary career and create their version of The Multipurpose Retirement.™ He created his own next chapter after a 26-year c...

Auburn on Main
Episode 51 | do you know where your children are? at City of Auburn camps!

Auburn on Main

Play Episode Listen Later Aug 27, 2025 43:10 Transcription Available


Every summer, over a dozen camp counselors work around the clock at our City of Auburn Parks, Arts and Recreation department to do it all -- look after your kids, teach your kids, mentor your kids, feed your kids, and most importantly, wear them out so they're kind and docile by the end of the day. But really though, City of Auburn summer camps are the bees knees and today we're joined by counselors Maddy Lindsay and Simon Berry, two strapping young Gen Zers who have spent years overseeing camps at the City. We chat about why it's a great program, why the kids have so much fun, and why becoming a slow rapper is every boy's dream. We finish strong with COA camp trivia, so stick around and test your knowledge of this amazing sumemr program! Keep this page bookmarked for next spring and sign up once camps open! But be quick -- they go fast. https://www.auburnwa.gov/city_hall/parks_arts_recreation/recreation/summer_camps Want to get notified when things happen? Sign up for email alerts: https://public.govdelivery.com/accounts/WAAUBURN/subscriber/new

The Dream Journal
Soul Reconciliation with Amy Jo Ellis and the Court of Atonement

The Dream Journal

Play Episode Listen Later Aug 25, 2025


Can’t see your way through a difficult situation? Try asking all Souls concerned to discuss issues until they understand why things happened, because once the Soul understands, forgiveness takes place. Today we speak with Amy Jo Ellis, founder of the Court of Atonement. Amy Jo describes herself as a reluctant spiritual medium who was thrust into the world of mediumship when her boss was murdered and she found herself seeing visions of what had happened. Amy Jo describes how her mother’s visions helped her develop her Court of Atonement process. After the break, we talk about how to resolve the energy of a nightmare, and Amy Jo takes me (and the listeners) through a CoA process to help me be more accepting of help. We end by talking about to cost of worry and how to move from anxiety to surrender. BIO: Amy Jo Ellis is a spiritual medium who channeled the conflict resolution technique “The Court of Atonement,” which has gained worldwide exposure. She's with us today because the validity of the process was revealed to her in dreams. Not just her dreams, but also her mother’s.  Find our guest at: CourtofAtonement.com FB: @courtofatonement IG: court_of_atonement X: amyjoellis This show, episode number 325, was recorded during a live broadcast on August 23, 2025 at KSQD.org, community radio of Santa Cruz. Intro and outro music by Mood Science. Ambient music new every week by Rick Kleffel. Archived music can be found at Pandemiad.com. Many thanks to Rick for also engineering the show and to Tony Russomano for answering the phones. The Santa Cruz Festival of Dreams is coming October 10-12, 2025! Early bird discount available now at FestivalofDreams.net Follow us at our FB group page HERE or follow #KeepSantaCruzDreaming on FB and IG. SHARE A DREAM FOR THE SHOW or a question or enquire about being a guest on the podcast by emailing Katherine Bell at katherine@ksqd.org. Follow on FB, IG, LI, & YT @ExperientialDreamwork #thedreamjournal. To learn more or to inquire about exploring your own dreams go to ExperientialDreamwork.com. The Dream Journal aims to: Increase awareness of and appreciation for nightly dreams. Inspire dream sharing and other kinds of dream exploration as a way of adding depth and meaningfulness to lives and relationships. Improve society by the increased empathy, emotional balance, and sense of wonder which dream exploration invites. A dream can be meaningful even if you don’t know what it means. The Dream Journal is produced at and airs on KSQD Santa Cruz, 90.7 FM. Catch it streaming LIVE at KSQD.org 10-11am Pacific Time on Saturdays. Call or text with your dreams or questions at 831-900-5773 or email at onair@ksqd.org. Podcasts are available on all major podcast platforms the Monday following the live show. The complete KSQD Dream Journal podcast page can be found at ksqd.org/the-dream-journal/. Closed captioning is available on the YouTube version of this podcast and an automatically generated transcript is available at Apple Podcasts. Thanks for being a Dream Journal listener! Available on all major podcast platforms. Rate it, review it, subscribe, and tell your friends.

Pew Time
193: New revolvers, Chicago loses a buyback gun, Interview w/ Big Bearded Gunner

Pew Time

Play Episode Listen Later Aug 12, 2025 71:41


193: On this episode, new revolvers from Smith and Wesson the 940 steel j-frame in 9mm and the Model 20. Glock stops civilian COA fulfillment, hopefully temporary. Chicago is being sued for a woman getting shot with a firearm from a buyback!ALSO, Tony interviews EJ “Big Bearded Gunner” to talk about what it is like to just kinda get into performance shooting in the modern age. If you guys want to save some on your own set of sexy Italian wood furniture from Woox for your shotgun or AR be sure to usecode: laughnload10For that Blackout Coffee link to support the show click https://www.blackoutcoffee.com?p=SJxs6gMea Be sure to use code LNL20 if it is your first order and get 20% off!Thanks for all of your guy's support! We love ya!Please help us out by rating and reviewing the podcast! Thank you!Got questions? Email us at pewtimepodcast@gmail.comIf you want to book Tony for a class email him at performancegun@gmail.com Looking for some new range wear?Head over to https://www.laughnload.com to check out some of the shirts, hats, hoodies and more that are currently available. What to check out some more from us you can search Laugh n Load on IG, FB and YouTube. FB: https://www.facebook.com/252407111792056/IG: https://instagram.com/laughnload?igshid=tm0tboj9syruYT: https://www.youtube.com/channel/UCvK8P5NQ_sCpz1Hwasmd62Q

Firearms Radio Network (All Shows)
Pew Time 193 – New revolvers, Chicago loses gun from a buy back & Interview w/ Big Bearded Gunner

Firearms Radio Network (All Shows)

Play Episode Listen Later Aug 11, 2025


193: On this episode, new revolvers from Smith and Wesson the 940 steel j-frame in 9mm and the Model 20. Glock stops civilian COA fulfillment, hopefully temporary. Chicago is being sued for a woman getting shot with a firearm from a buyback! ALSO, Tony interviews EJ “Big Bearded Gunner” to talk about what it is like to just kinda get into performance shooting in the modern age. If you guys want to save some on your own set of sexy Italian wood furniture from Woox for your shotgun or AR be sure to use code: laughnload10 For that Blackout Coffee link to support the show click https://www.blackoutcoffee.com?p=SJxs6gMea Be sure to use code LNL20 if it is your first order and get 20% off! Thanks for all of your guy's support! We love ya! Please help us out by rating and reviewing the podcast! Thank you! Got questions? Email us at pewtimepodcast@gmail.com If you want to book Tony for a class email him at performancegun@gmail.com Looking for some new range wear? Head over to https://www.laughnload.com to check out some of the shirts, hats, hoodies and more that are currently available. What to check out some more from us you can search Laugh n Load on IG, FB and YouTube. FB: https://www.facebook.com/252407111792056/ IG: https://instagram.com/laughnload?igshid=tm0tboj9syru YT: https://www.youtube.com/channel/UCvK8P5NQ_sCpz1Hwasmd62Q

Master Brewers Podcast
Episode 200: Reconsidering the Congress Mash

Master Brewers Podcast

Play Episode Listen Later Aug 4, 2025 49:19


Should the numbers on your malt COA be produced from a mash that's more similar to your brewery mashes? Did you know that's already happening when you buy UK malt? Listen up, then join the conversation (https://community.mbaa.com/communities/community-home/digestviewer/viewthread?GroupId=37&MessageKey=c1d189f2-57d6-4047-8b26-f993a3f04a11&CommunityKey=cb7fc054-5008-4b01-87f3-588d3c711e07&tab=digestviewer&ReturnUrl=%2fcommunities%2fcommunity-home%2fdigestviewer%3ftab%3ddigestviewer%26CommunityKey%3dcb7fc054-5008-4b01-87f3-588d3c711e07). Special Guests: Glen Fox and Mary-Jane Maurice.

Dr. Joseph Mercola - Take Control of Your Health
Why Skipping Beef Liver Could Hurt Your Pancreas - AI Podcast

Dr. Joseph Mercola - Take Control of Your Health

Play Episode Listen Later Jul 31, 2025 7:59


Story at-a-glance Research shows vitamin B12 rapidly replenishes adenosine triphosphate (ATP) levels in pancreatic cells, preventing destructive enzyme activation that causes acute pancreatitis inflammation People with naturally higher vitamin B12 levels show significantly lower risk of developing acute pancreatitis, independent of lifestyle factors Vitamin B12 enhances energy metabolism by converting methylmalonyl-CoA to succinyl-CoA, stabilizing cell membranes and containing digestive enzymes properly Early vitamin B12 administration provides greatest protection, with 1,000-2,000 micrograms daily recommended for supplementation or monthly injections for severe deficiency Combine vitamin B12-rich foods like grass fed liver alongside minimal vegetable oil intake and regular exercise to support overall pancreatic health

The Kevin Jackson Show
Unchained Leftism - Ep 25-282

The Kevin Jackson Show

Play Episode Listen Later Jul 15, 2025 38:40


Chicago Public Schools has a $734M deficit after paying for illegals.These are funds that should ONLY go to American citizens. When they do bond elections for education, do you want to pay to educate the children of illegals? CPS is laying off. That's the best news for CPD they've had in years. 1458 employees will be laid off.432 teachers, 677 special ed classroom assistants.Sex Offender freed in COA sex offender was freed, and he was caught on camera trying to abduct a childhttps://nypost.com/2025/07/14/us-news/registered-sex-offender-to-walk-free-after-elementary-school-kidnapping-attempt-prosecutors-say/See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Going North Podcast
Ep. 976 – Flex Your Feelings with Dr. Emily Anhalt (@dremilyanhalt)

Going North Podcast

Play Episode Listen Later Jul 9, 2025 32:27


“Writing a book is really vulnerable in a way I wasn't necessarily expecting. I'm used to putting myself out there, but writing a book is being vulnerable on a really grand scale.” – Dr. Emily Anhalt Today's featured author is a clinical psychologist, consultant, TEDx speaker, and cofounder of Coa, the gym for mental health, Dr. Emily Anhalt. Dr. Emily and I had a fun on a bun chat about her book, “Flex Your Feelings: Train Your Brain to Develop the 7 Traits of Emotional Fitness”, her writing process, practical tips for building emotional resilience, and more! Key Things You'll Learn:What inspired Dr. Emily to study psychologyWhat she learned about herself through writing her bookWhat emotional push-ups are and how to develop emotional fitnessWhat setback led Dr. Emily to create more successDr. Emily's Site: https://www.dremilyanhalt.com/bookDr. Emily's Book: https://a.co/d/3K0dOzUDr. Emily's TEDx Talk: https://youtu.be/EAeEQvj16XM?si=8y9B0Z2g_4ZZPtGC The opening track is titled, “North Wind and the Sun” by Trevin P. To listen to and download the full track, click the following link. https://compilationsforhumanity.bandcamp.com/track/north-wind-and-the-sunPlease support today's podcast to keep this content coming! CashApp: $DomBrightmonDonate on PayPal: @DBrightmonBuy Me a Coffee: https://www.buymeacoffee.com/dombrightmonGet Going North T-Shirts, Stickers, and More: https://www.teepublic.com/stores/dom-brightmonThe Going North Advancement Compass: https://a.co/d/bA9awotYou May Also Like…Ep. 596 – “The Self-Healing Mind” with Dr. Gregory Scott Brown (@GregorySBrownMD): https://www.goingnorthpodcast.com/ep-596-the-self-healing-mind-with-dr-gregory-scott-brown-gregorysbrownmd/Ep. 785 – The Enjoyment Gap with Mandy Barbee Lanier (@mandyblanier): https://www.goingnorthpodcast.com/ep-785-the-enjoyment-gap-with-mandy-barbee-lanier-mandyblanier/Ep. 455.5 – “From Triggered to Tranquil” with Dr. Susan Campbell (@drsusan99): https://www.goingnorthpodcast.com/ep-4555-from-triggered-to-tranquil-with-dr-susan-campbell-drsusan99/Ep. 424 – “Thoughtfully Fit” with Darcy Luoma (@DarcyLuoma): https://www.goingnorthpodcast.com/ep-424-thoughtfully-fit-with-darcy-luoma-darcyluoma/280 – “Architect of BEing” with Dr. Travis Fox (@travisfox360): https://www.goingnorthpodcast.com/280-architect-of-being-with-dr-travis-fox-travisfox360/110 - "Self-Intelligence" with Jane Ransom (@TheJaneRansom): https://www.goingnorthpodcast.com/110-self-intelligence-with-jane-ransom-thejaneransom/Ep. 691 – “How to Spark Your Heart and Ignite Your Life” with Hilary DeCesare (@HilaryDeCesare): https://www.goingnorthpodcast.com/ep-691-how-to-spark-your-heart-and-ignite-your-life-with-hilary-decesare-hilarydecesare/Ep. 419 – “Overcoming Toxic Emotions” with Leah Guy: https://www.goingnorthpodcast.com/ep-419-overcoming-toxic-emotions-with-leah-guy/97.5 (Thanksgiving Bonus Episode) - "MindShift On Demand" with Donna Blevins (@BigGirlPoker): https://www.goingnorthpodcast.com/975-thanksgiving-bonus-episode-mindshift-on-demand-with-donna-blevins-biggirlpoker/Ep. 587 – “Cadence” with Leanne Spencer: https://www.goingnorthpodcast.com/ep-587-cadence-with-leanne-spencer/Ep. 910 – How to Eliminate the Beliefs That Sabotage Your Business & Your Life with Shelly Lefkoe: https://www.goingnorthpodcast.com/ep-910-how-to-eliminate-the-beliefs-that-sabotage-your-business-your-life-with-shelly-lefkoe/Ep. 639 – “Mind Control” with Danielle Matthews: https://www.goingnorthpodcast.com/ep-639-mind-control-with-danielle-matthews/75 - "Life Falls Apart, But You Don't Have To" with Julie Potiker (@JuliePotiker): https://www.goingnorthpodcast.com/75-life-falls-apart-but-you-dont-have-to-with-julie-potiker-juliepotiker/Ep. 865 – Bringing Sunshine Back To My Mind with Dr. Momoko Uno: https://www.goingnorthpodcast.com/ep-865-bringing-sunshine-back-to-my-mind-with-dr-momoko-uno/