Podcasts about nikolsky

Do you have a hard time differentiating two commonly tested autoimmune blistering skin disorders of pemphigus vulgaris and bullous pemphigoid? Which one is associated with Nikolsky sign, and which one has antibodies against the hemi-desmosomes? If you feel like you need to review these concepts and find memory devices to make them stick, tune into this episode hosted by our newest team member MS3 Alicia Podwojniak!

Hello everyone, This is Mirko Guerrini, and I welcome you to the Jazz Transcription Clinic, a monthly interviews podcast where we talk with accomplished jazz doctors about their lives, careers and personal transcription secrets.  On this episode of the Jazz Transcription Clinic Podcast, Mirko Guerrini interviews the guest jazz doctor: Tim Nikolsky. Listen to Tim's answers to the questions below:  00:00 Introduction 15:22 Why do you transcribe? 29:32 What do you expect to bring home with a transcription? 39:26 How do you choose the solos you transcribe? 42:16 What is your methodology? 51:33 Do you write it down? If not, why? 01:07:44 Who was the most difficult player you transcribed? 01:15:52 Which transcription you've done is your favourite? Dr. Tim Nikolsky is a Melbourne based musician, educator, tech guy, PhD graduate, cyclist, enthusiastic homebrewer and most of the time an all round pretty good guy. His PhD on the development of the Australian Jazz Real Book is the first of its kind in Australia, has won him accolades as well as earning him some enemies, but is widely regarded as a long overdue valuable resource. Tim has written, recorded and produced several albums, and plays in several bands around Melbourne on guitar, electric and double bass. You can check Tim Nikolsky's works here: https://australianjazzrealbook.com/

Ten years after the revolutionary blockbuster Beginning of the Great Revival was released, a new film, tracing the formation of the Communist Party of China 100 years ago, is set to open on Thursday.在革命大片《伟大复兴的开端》上映十年后，一部追溯100年前中国共产党形成的新电影将于周四上映。Veteran filmmaker Huang Jianxin, who co-directed the movie with Han Sanping, had often pondered on revisiting the history with a more human-interest and dramatic tune. And, with the release of 1921－the biggest tribute film to mark the centenary of the Party－the 67-year-old auteur has fulfilled his wish.与韩三平共同执导这部电影的资深电影人黄建新经常考虑以更有人情味和戏剧性的风格来重温这段历史。随着《一九二一》--纪念建党一百周年的最大一部献礼影片的发行，这位67岁的导演实现了他的愿望。As of Wednesday, a day before its nationwide release, the movie raked in more than 92 million yuan ($14.25 million) in presale receipts, making it quite possibly the new domestic box-office champion, according to industry observers.据行业观察人士称，截至周三，在全国范围内上映的前一天，这部电影的预售收入超过了9200万元，很可能成为新的国内票房冠军。The film is also set to be released in the United Kingdom, Ireland and the United Arab Emirates, its distributors say.该片的发行商说，该片还将在英国、爱尔兰和阿拉伯联合酋长国上映。Besides, it will also be simultaneously released to the North American audience via Smart Cinema USA, a mobile cinema app.Unlike Beginning of the Great Revival, which covers 1911-21, the latest film is narrated over a shorter and more compact course in the title year, when the Party held its first National Congress in Shanghai and Jiaxing, Zhejiang province, in the summer of 1921, laying the foundation for its rise.此外，它还将通过移动影院应用程序Smart Cinema USA向北美观众同步发行。与涵盖1911-21年历史的《伟大复兴的开端》不同，新的影片叙述内容的时间更集中、更紧凑。主要讲述1921年夏天，党在上海和浙江嘉兴召开第一次全国代表大会，为其崛起奠定的基础。Continuously employing the successful stardom formula, an innovation for revolutionary films starting from The Founding of a Republic (2009), which was also jointly directed by Huang and Han, 1921 casts legions of A-listers to play historical figures, ranging from the founding members of the CPC to political celebrities and the notorious Chinese police officers in Shanghai's foreign concessions.电影《1921》依旧选择以成功的群星汇聚的方式演绎，这也是革命电影的一个创新。从《建国大业》（2009年）开始，《1921》也选取了大量的重量级明星来扮演历史人物：从中国共产党的创始人到有名的政治家，以及上海外国租界中臭名昭著的中国警察。Chen Kun and Li Chen respectively play Party founders Chen Duxiu and Li Dazhao. Huang Xuan and Ni Ni star as the couple of Li Da, one of the early Party leaders, and his wife, Wang Huiwu.陈坤和李晨分别扮演党的创始人陈独秀和李大钊。黄轩和倪妮饰演党的早期领导人之一的李达和他的妻子王会悟夫妇。Actor Wang Renjun reprises the character of Chairman Mao Zedong after his 2019 military film, The Bugle of Gutian.演员王仁君继2019年的军事电影《古田军号》之后再次扮演毛泽东主席。Zhu Yilong stars as China's first premier, Zhou Enlai, turning 23 years old in 1921. Wang Yuan plays the role of Chinese leader Deng Xiaoping, then aged 17.朱一龙饰演中国第一位总理周恩来，1921年年满23岁。王源饰演中国领导人邓小平，当时17岁。Recalling that he was invited to return to the familiar subject in 2016, director Huang Jianxin, who also serves as the executive producer, says it was stressful to seek a breakthrough in storytelling, as he worried that old-school filmmaking would fail to hook young people, the mainstream theatergoers.同时担任执行制片人的导演黄建新说，这部影片让他又回到了在2016年同样让他苦思冥想的问题。寻求故事性的突破是很有压力的，因为他担心老派的电影制作无法吸引年轻人，他们也是主流的影院观众。Newly discovered documents from the early 1920s, especially from archives in Europe and Japan, have helped the creators to piece together the backgrounds of the 13 representatives, including New China's first leader, Mao, who gathered for the first Party congress.新发现的20世纪20年代初的文件，特别是来自欧洲和日本的档案，帮助创作者拼凑出了参加第一次党代会的包括新中国的第一位领导人毛泽东共13位代表的历史背景。"We also wanted to retell the history from an international point of view. The founding of the CPC was helped by overseas communists, making it possible to conceive parallel plotlines taking place overseas," says Huang Jianxin."我们还想从国际角度来重述这段历史。黄建新说：“中国共产党的成立得到了海外共产党人的帮助，这使得我们构想出在海外发生的相似情节。Led by Vladimir Lenin, the Moscow-headquartered Communist International (1919-43) assigned Dutch communist Henk Sneevliet, who went by the pseudonym Maring, and Russian delegate Nikolsky to help Chinese people to found the CPC in 1921, according to records.根据记录，在弗拉基米尔·列宁的领导下，总部设在莫斯科的共产国际（1919-43年）指派化名为马林的荷兰共产党人亨克·斯内夫利特和俄国代表尼科尔斯基帮助中国人在1921年成立了中国共产党。Coupled with inspiration from an unsealed archive found in Japan, the film 1921 adds espionage genre elements, exemplified by scenes featuring a Japanese spy sent to Shanghai and the two Comintern delegates escaping in a death-defying car chase.加上从日本发现的未封存的档案中获得的灵感，电影《1921》还增加了间谍类型的元素，例如日本派往上海的间谍和两名共产国际代表在一场死亡的汽车追逐中逃跑的场景。"When we were conducting our research, we found that Japan was keeping a close eye on the communist activities in the period－it actively supported and nurtured pro-Japan forces in China," says Zheng Dasheng, a Shanghai native and co-director of 1921.“当我们进行研究时，我们发现日本当时在密切关注这一时期的共产主义活动，它也催生了中国的亲日派，”郑大圣说。他是上海人，也是《1921》的联合导演。日本政府当时对一大的密切关注，以及对激进的日本人在上海接触具有共产主义思想观念的中国人的警惕"Besides, the situation in Shanghai was quite complicated with the foreign settlements."“此外，上海的情况也相当复杂，因为还有外国人的居留区存在”。For directors Huang Jianxin and Zheng, their other goal was to explore and explain how the faith of communism was shaped, hence helping a wider viewership to understand why revolutionary pioneers risked their lives to pursue the rise of China amid the warlords' disunity and foreign oppression.对于导演黄建新和郑大圣来说，他们的另一个目标是探索和解释共产主义的信仰是如何形成的，从而帮助更多的观众了解为什么革命先驱在军阀混战和外国压迫中冒着生命危险追求中国的崛起。"The average age of the 13 delegates who took part in the first CPC National Congress was around 28 years old. There were about 50 members when the Party was founded in 1921, and it was those people who had changed the fate of our country," Huang Jianxin says.“参加中共第一次全国代表大会的13名代表的平均年龄约为28岁。1921年建党时，大约有50名党员，正是这些人改变了我们国家的命运，”黄建新说。"It was also the original impetus to drive us to work on the project for five years," he adds.“这也是驱使我们为这个项目工作五年的原始动力，”他补充说。In an effort to ensure historical reality, the crew built real-size replicas of the sites of CPC's first and second National Congress and Bowen Girls' School, where the first congress delegates were accommodated for safety concerns.为了确保历史的真实性，剧组建造了真实1：1的中国共产党第一次和第二次全国代表大会会址以及博文女校的布景。在真实历史事件中，出于安全考虑，第一次代表大会的代表们就住在那里。Besides, some historical details, such as rickshaw license plates from Shanghai－usually each installed with two plates respectively for being allowed to move around the foreign concessions and other areas of the city－are reflected in the film.此外，一些历史细节，也反映在了影片中。如上海的人力车通常都会安装两块车牌，以获准在外国租界和城市的其他地区活动。With some imagination, based on documents from Chinese and foreign archives and libraries, character arcs are also convincingly developed, according to some critics who saw previews.据一些看过试映的评论家说，电影根据中国和外国档案馆和图书馆的文件来进行合理想象，人物角色都演绎出了令人信服的角色发展。Such scenarios include Li Da's romantic moments with his newlywed wife; Mao and several delegates asking a laundry's employee to help them wash the suits they would wear for the National Congress; and He Shuheng, the oldest of the 13 delegates, urging Mao to bid farewell to his wife shortly before their ship sailed from Hunan province for Shanghai.这些场景包括李达与新婚妻子的浪漫时刻；毛泽东和几位代表要求洗衣店的员工帮助他们清洗将在全国代表大会上穿的西装；以及13位代表中年龄最大的何叔衡，在他们的船从湖南开往上海前不久，敦促毛泽东向妻子告别。"The film skillfully blends suspense and history to take a retrospective look at the first batch of CPC members' endeavor to save the nation from subjugation and ensure its survival," says Rao Shuguang, head of the China Film Critics Association.“这部电影巧妙地融合了悬念和历史，回顾了第一批中共党员为国家救亡图存所做的努力，”中国电影评论家协会负责人饶曙光说。"It has also updated filmmaking and storytelling techniques for revolutionary features."“它还改变了革命题材的电影制作和讲故事的手法。”记者：徐帆

Welcome To The MedFlashGo Podcast. This Is Your Daily 4 Minutes Or Less Rapid Review for medical students. Topics are based on medical board examinations including USMLE, COMLEX, And Shelf Exams. We release a new episode every weekday! In this question of the day, Percy asks students to correctly diagnose the patient in the given presentation. These questions are powered by MedFlashGo The First Voice-based interactive medical question bank currently available on Alexa. This tool allows medical students to study medical topics and be interactively tested without the use of a screen. You can study on your couch, in your car, and on the move without the use of a screen. To get access to the free audio-interactive question bank, click here or go to your Alexa application and search medflashgo In the skills section. To learn more details go to medflashgo.com and check out our frequently asked questions section. Please know that these questions were creatively designed by medical students and physicians for the purpose of education and do not replace health information given from your health professionals. We have tried our best to make sure the information is accurate please, so please let us know if you find any errors and we will be sure to correct them. --- Send in a voice message: https://anchor.fm/medflashgo/message

Pemphigus is an uncommon intraepidermal blistering disease occurring on the skin and mucous membranes. It is caused by autoantibodies to adhesion molecules expressed in the skin and mucous membranes. The cause is unknown. The bullae appear spontaneously and are tender and painful when they rupture. Drug induced pemphigus from penicillamine, captopril, and others have been reported. There are several forms of pemphigus: pemphigus vulgaris and its variant, pemphigus vegetans; and the more superficially blistering pemphigus foliaceus and its variant, pemphigus erythematosus. All forms may occur at any age, but most present in middle age. The foliaceus form is especially apt to be associated with other autoimmune diseases, or it may be drug induced. Paraneoplastic pemphigus, a unique form of the disorder, is associated with numerous types of benign and malignant neoplasms (typically non-Hodgkin lymphoma). Pemphigus is characterized by an insidious onset of flaccid bullae, crusts, and erosions in crops or waves. In pemphigus vulgaris, lesions often appear first on the oral mucous membranes. These quickly become erosive. The scalp is another site of early involvement. Practitioners can rub a cotton swab or finger laterally on the surface of uninvolved skin which may cause easy separation of the epidermis (this is Nikolsky's sign). The diagnosis is made with light microscopy and by direct and indirect immunofluorescence (IIF) microscopy. Autoantibodies to intercellular adhesion molecules can be detected with ELISA assays and have replaced the use of IIF in some centers. When the condition is severe, patients should be hospitalized at bed rest and given antibiotics/intravenous feedings. Anesthetic troches used before eating ease painful oral lesions. While pemphigus requires systemic therapy as early as possible, ironically, the main morbidity here is side effects from treatment. Initial therapy with systemic corticosteroids can consist of prednisone (60-80 mg daily). In most cases, a steroid sparing agent is added at the beginning at treatment (ex. azathioprine 100-200 mg daily, mycophenolate mofetil 1-1.5 twice daily). Treatment courses can be repeated in patients who do not achieve complete remission or relapse (ex. monthly IVIG at 2 g/kg intravenously over 3-4 days). In refractory cases, cyclophosphamide plus intravenous corticosteroids and plasmapheresis are also used. In patients who have a limited form of the disease, skin and mucous membrane lesions should be treated with topical corticosteroids. Complicating infection requires appropriate systemic and local antibiotic therapy. As far as complications are concerned, secondary infection can occur. This is a major cause of morbidity and mortality. Disturbances of fluid, electrolyte, and nutritional intake can occur as a result of painful oral ulcers. One in three patients will experience remission and, infection from S. aureus is the most frequent fatality cause. --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app

Tackle rashes with wisdom from Kashlak’s resident Skinternist (or Internist-Externist) Dr. Helena Pasieka (MedStar, Georgetown), board certified in both Internal Medicine and Dermatology.  She offers “a rash approach to rashes” including: initial triage, ‘inside job’ vs ‘outside job’, differential diagnosis, a review of common culprits, basic management techniques, and how to determine if the reaction is life-threatening. Plus, Dr Pasieka teaches us how to handle family and friends asking, “Can you take a look at this rash?”.  Full show notes at https://thecurbsiders.com/podcast. Join our mailing list and receive a PDF copy of our show notes every Monday. Rate us on iTunes, recommend a guest or topic and give feedback at thecurbsiders@gmail.com. Credits Written and Produced: Beth Garbitelli MS2 Infographic and Cover Art: Beth Garbitelli MS2 Hosts: Stuart Bringham MD, Matthew Watto MD, Paul Williams MD   Editor: Matthew Watto MD Guest: Helena Pasieka MD  Time Stamps 00:00 Intro, disclaimer, guest bio 04:10 Guest one-liner, book recommendations  09:56 Case of a rash; initial thought process (sick versus not sick); review of systems 18:05 Grouping rashes: inside job versus outside job 22:07 Terminology: Many people dont speak derm 26:03 Skin itching versus Skin pain; Morbilliform drug eruption 30:08 Urticaria (hives) vs morbilliform rash; Cotton tipped applicators and dermatographism 35:42 Itching is not all about histamine; Treatment of hives 38:26 Treatment of morbilliform rash 40:00 Case summary and review of concepts learned thus far 41:00 AGEP 45:14 SJS/TEN; Nikolsky’s sign 53:20 Complications of TEN - Ocular surface disease; Vulvar disease 58:02 DRESS (now DIHS) 66:30 Tips for asking about time course of meds and symptoms; Recap of DRESS (DISH) 70:00 How to handle family and friends ask for rash evaluation 76:20 Outro 78:00 Post-credits scene

  In this episode, three dermatology residents -- Dr. Daniel Mazori,  Dr. Julie Croley, and Dr. Elisabeth Tracey -- discuss items they keep in their on-call bags in this special resident takeover of the podcast. Beginning at 14:50, they talk about premade biopsy kits, tricks for achieving hemostasis in the hospital, portable electronic gadgets, and creative alternatives for basic items. They also discuss bedside diagnostics and unique cases while being on-call. “After rotating through the consult service, you really do grow as a dermatologist,” reports Dr. Croley. “You see rare things; you see severe disease processes. You learn to be efficient and self-sufficient.”  We also bring you the latest in dermatology news and research: 1. Study finds inconsistent links with aspirin, nonaspirin NSAIDs, and reduced skin cancer risk. 2. Justin M. Ko, MD, MBA, of Stanford (Calif.) University discusses the American Academy of Dermatology's position statement on augmented intelligence. Dr. Ko is director and chief of medical dermatology for Stanford Health Care at Stanford Medicine, Redwood City, Calif. He is the chair of the AAD's Ad Hoc Taskforce on Augmented Intelligence, which wrote the position statement. 3. Prior authorizations for dermatology care nearly doubled in the last 2 years at one center. Things you will learn in this episode: Recommendations on what type of bag to use for your on-call bag. Premade biopsy kits are key for your on-call bag so that you can perform shave or punch biopsies. Tricks for obtaining hemostasis in the hospital. The utility of dermatoscopes has been expanding in recent years, and it can be a helpful bedside electronic device. Purple surgical markers can be used as a topical antimicrobial. Normal saline or honey can be used if you run out of Michel solution. Nonmedical items to keep in your on-call bag may include a handheld guide for drug eruptions and consult templates. Examples of unique cases of misdiagnosed Stevens-Johnson syndrome, highlighting the expertise of dermatologists: “In our field, especially as a consultant, our expertise can be so crucial in the care of complex patients.” Be comfortable with bedside diagnostics such as Tzanck smear to diagnose viral infections and a positive Nikolsky sign for staphylococcal scalded skin syndrome. Hosts: Elizabeth Mechcatie, Terry Rudd Guests: Daniel R. Mazori, MD (State University of New York, Brooklyn); Julie Ann Amthor Croley, MD (the University of Texas Medical Branch at Galveston); and Elisabeth (Libby) Tracey, MD (Cleveland Clinic Foundation). Show notes by Melissa Sears, Alicia Sonners, and Elizabeth Mechcatie. Contact us: podcasts@mdedge.com Twitter: @MDedgeDerm Rate us on iTunes! To subscribe to this podcast and more, go to mdedge.com/podcasts.

This episode covers Chapter 110 of Rosen’s Emergency Medicine (9th Ed.), Dermatologic Presentations.  Episode Overview List five broad categories of rashes Describe the primary skin lesion types  a. Bonus: What are the secondary skin lesions (show notes only) List systemic diseases that present with cutaneous signs for each of the following locations: Generalized rash Head and neck Hands Legs Palms and Soles Describe the various presentations of tinea and their treatment List 8 RFs for candida infections Describe the stepwise management of diaper dermatitis Describe the distribution of Pityriasis rosea Describe the management of atopic dermatitis Describe the management of impetigo & folliculitis List 6 RFs of C.A.-MRSA and 4 oral Abx treatments Describe the presentation and management of Staph Scalded Skin andTSS List 10 causes of EM / SJS / TEN Describe presentation of EM + SJS/TEN. Differentiate between TEN and SJS List 6 broad categorical causes of urticaria Describe the typical features for each of the following: Measles Rubella Roseola Infantum Erythema Infectiosum Scarlet Fever Describe treatment of poison ivy Describe presentation and treatment of Pediculosis + Scabies List 10 causes of Erythema Nodosum List a 6 ddx for vesicular lesions List 4 lesions with a positive Nikolsky’s sign List 4 complications of HSV infection List 5 complications of Varicella + describe the management of an exposure during pregnancy List 5 complications of Zoster + differentiate between Ophthalmicus and Oticus What is the treatment of herpes zoster? Wisecracks List 5 causes of desquamating lesions List 5 palm and sole rashes List 10 maculopapular rashes List 1 low, medium and high potency topical steroid Identify the following rashes: erythema migrans, erythema marginatum, erythema multiforme, erythema nodosum, meningococcemia

This episode covers Chapter 110 of Rosen’s Emergency Medicine (9th Ed.), Dermatologic Presentations.  Episode Overview List five broad categories of rashes Describe the primary skin lesion types  a. Bonus: What are the secondary skin lesions (show notes only) List systemic diseases that present with cutaneous signs for each of the following locations: Generalized rash Head and neck Hands Legs Palms and Soles Describe the various presentations of tinea and their treatment List 8 RFs for candida infections Describe the stepwise management of diaper dermatitis Describe the distribution of Pityriasis rosea Describe the management of atopic dermatitis Describe the management of impetigo & folliculitis List 6 RFs of C.A.-MRSA and 4 oral Abx treatments Describe the presentation and management of Staph Scalded Skin andTSS List 10 causes of EM / SJS / TEN Describe presentation of EM + SJS/TEN. Differentiate between TEN and SJS List 6 broad categorical causes of urticaria Describe the typical features for each of the following: Measles Rubella Roseola Infantum Erythema Infectiosum Scarlet Fever Describe treatment of poison ivy Describe presentation and treatment of Pediculosis + Scabies List 10 causes of Erythema Nodosum List a 6 ddx for vesicular lesions List 4 lesions with a positive Nikolsky’s sign List 4 complications of HSV infection List 5 complications of Varicella + describe the management of an exposure during pregnancy List 5 complications of Zoster + differentiate between Ophthalmicus and Oticus What is the treatment of herpes zoster? Wisecracks List 5 causes of desquamating lesions List 5 palm and sole rashes List 10 maculopapular rashes List 1 low, medium and high potency topical steroid Identify the following rashes: erythema migrans, erythema marginatum, erythema multiforme, erythema nodosum, meningococcemia

Roy Plomley's castaway is former lady's maid to Lady Astor, Rosina Harrison. Favourite track: Bless This House by Webster Booth Book: Oliver Twist by Charles Dickens Luxury: Picture called Summer Arangments by Nikolsky