Podcasts about Drug

Chad Lowe is mourning his 13-year-old daughter, Harry and Meghan are blasting “reckless” paparazzi outside their children’s school, and Pete Davidson reveals the shocking drug use that sent him to rehab. Rob’s latest exclusives and insider reporting can be found at robshuter.substack.com My new novel, Queen Elizabeth III, is available for pre-order right nowSee omnystudio.com/listener for privacy information.

"You're gonna need a bigger boat!" Today we discuss the third compound going to clinic emerging from Neil Camarta's "Shark Tank" meetings. This one from Satellos was designed to address the regeneration deficit in DMD caused by reduced asymmetric muscle stem cell division, and is now being repurposed for FSHD to potentially boost muscle regeneration regardless of DUX4 status.

Lone star tick bites can cause alpha-gal syndrome, which involves an allergic reaction to red meat and other animal products. Learn more at https://www.yaleclimateconnections.org/ 

This is the 73rd episode in my drug pronunciation series. In this episode, I divide hydrochlorothiazide into syllables, tell you which syllables to emphasize, list my sources, and introduce some bonus topics: one pronunciation variation and two abbreviations.    Why did I pick hydrochlorothiazide for this episode? It is frequently prescribed. It's a long, intimidating drug name. It is found in combination with other blood pressure medications. It's a drug name in my pronunciation course, which ends in December 2026.    There are still more than 50 drug names in the course that have not been part of the pronunciation series. It is my goal to include all 50+ in the drug pronunciation series eventually.    ❌ We don't cover pharmacology in this series. Just pronunciations.   ⭐️ Sign up for The Pharmacist's Voice ® monthly email newsletter! https://bit.ly/3AHJIaF ⭐️   Hydrochlorothiazide = HYE-droe-KLOR-oh-THYE-a-zide (7 syllables) HYE, like high blood pressure droe, like a drone KLOR, like chloride  oh, like the letter "O" in the alphabet THYE, like the body part, thigh a, which is a short "A" sound, like the "a" in adoption (uh) zide, which rhymes with tide, as in the ocean tide Emphasize HYE, KLOR, and THYE. THYE gets the most emphasis.  Written pronunciation source: MedlinePlus.gov  Spoken pronunciation example: Tony PharmD HCTZ pronunciation (YouTube)   Pronunciation Variation As an Ohio Pharmacist, I tend to say HYE-droe-KLOR-uh-THYE-a-zide instead of HYE-droe-KLOR-oh-THYE-a-zide. They sound VERY similar. The difference is "uh" vs "oh." Either spoken pronunciation will pass as correct. They're both "in the ballpark."   Two abbreviations HCTZ HCT   If you know someone who would like to learn how to say hydrochlorothiazide, please share this episode with them. Subscribe to or follow The Pharmacist's Voice ® Podcast on your favorite podcast player and YouTube, so you never miss an episode.    This podcast is on all major podcast players and YouTube. Popular links are below. ⬇️   Apple Podcasts   https://apple.co/42yqXOG  Spotify  https://spoti.fi/3qAk3uY  Amazon/Audible  https://adbl.co/43tM45P YouTube https://bit.ly/43Rnrjt   Host Background: Kim Newlove has been an Ohio pharmacist since 2001 (BS Pharm, Chem Minor). Her experience includes hospital, retail, compounding, and behavioral health. She is also an author, voice actor (medical narrator and audiobook narrator), podcast host, and consultant (podcasting and audiobooks).    Other episodes in this series The Pharmacist's Voice Podcast Episode 370, Pronunciation Series Episode 72 oseltamivir (Tamiflu) The Pharmacist's Voice Podcast Episode 364, Pronunciation Series Episode 71 (Dupixent) The Pharmacist's Voice Podcast Episode 362, Pronunciation Series Episode 70 (Corlanor) The Pharmacist's Voice Podcast Episode 360, Pronunciation Series Episode 69 (Kisunla) The Pharmacist's Voice Podcast Episode 358, Pronunciation Series Episode 68 (Journavx) The Pharmacist's Voice Podcast Episode 356, Pronunciation Series Episode 67 (Zanaflex) The Pharmacist's Voice Podcast Episode 352, Pronunciation Series Episode 66 (Yescarta) The Pharmacist's Voice Podcast Episode 350, Pronunciation Series Episode 65 (Xarelto) The Pharmacist's Voice Podcast Episode 349, Pronunciation Series Episode 64 (acetaminophen) The Pharmacist's Voice Podcast Episode 348, Pronunciation Series Episode 63 (Welchol/colesevelam) The Pharmacist's Voice Podcast Episode 346, Pronunciation Series Episode 62 (valacyclovir) The Pharmacist's Voice Podcast Episode 343, Pronunciation Series Episode 61 (ubrogepant) The Pharmacist's Voice Podcast Episode 341, Pronunciation Series Episode 60 (topiramate) The Pharmacist's Voice Podcast Episode 339, Pronunciation Series Episode 59 (Suboxone) The Pharmacist's Voice Podcast Episode 337, Pronunciation Series Episode 58 (rosuvastatin)  The Pharmacist's Voice Podcast Episode 335, Pronunciation Series Episode 57 (QVAR) The Pharmacist's Voice Podcast Episode 333, Pronunciation Series Episode 56 (pantoprazole)  The Pharmacist's Voice Podcast Episode 330, Pronunciation Series Episode 55 (oxcarbazepine) The Pharmacist's Voice Podcast Episode 328, Pronunciation Series Episode 54 (nalmefene) The Pharmacist's Voice Podcast Episode 326, Pronunciation Series Episode 53 (Myrbetriq) The Pharmacist's Voice Podcast Episode 324, Pronunciation Series Episode 52 (liraglutide)  The Pharmacist's Voice Podcast Episode 322, Pronunciation Series Episode 51 (ketamine) The Pharmacist's Voice Podcast Episode 320, Pronunciation Series Episode 50 (Jantoven) The Pharmacist's Voice Podcast Episode 318, Pronunciation Series Episode 49 (ipratropium) The Pharmacist's Voice Podcast Episode 316, Pronunciation Series Episode 48 (hyoscyamine) The Pharmacist's Voice Podcast Episode 313, Pronunciation Series Episode 47 (guaifenesin) The Pharmacist's Voice Podcast Episode 311, Pronunciation Series Episode 46 (fluticasone) The Pharmacist's Voice Podcast Episode 309, Pronunciation Series Episode 45 (empagliflozin) The Pharmacist's Voice Podcast Episode 307, Pronunciation Series Episode 44 (dapagliflozin) The Pharmacist's Voice Podcast Episode 304, Pronunciation Series Episode 43 (cetirizine)  The Pharmacist's Voice Podcast Episode 302, Pronunciation Series Episode 42 (buspirone)  The Pharmacist's Voice Podcast Episode 301, Pronunciation Series Episode 41 (azithromycin) The Pharmacist's Voice Podcast Episode 298, Pronunciation Series Episode 40 (umeclidinium) The Pharmacist's Voice Podcast Episode 296, Pronunciation Series Episode 39 (Januvia)  The Pharmacist's Voice Podcast Episode 294, Pronunciation Series Episode 38 (Yasmin) The Pharmacist's Voice Podcast Episode 292, Pronunciation Series Episode 37 (Xanax, alprazolam) The Pharmacist's Voice Podcast Episode 290, Pronunciation Series Episode 36 (quetiapine)  The Pharmacist's Voice Podcast Episode 287, pronunciation series ep 35 (bupropion) The Pharmacist's Voice Podcast Episode 285, pronunciation series ep 34 (fentanyl) The Pharmacist's Voice Podcast Ep 281, Pronunciation Series Ep 33 levothyroxine (Synthroid) The Pharmacist's Voice ® Podcast Ep 278, Pronunciation Series Ep 32 ondansetron (Zofran) The Pharmacist's Voice ® Podcast Episode 276, pronunciation series episode 31 (tocilizumab-aazg) The Pharmacist's Voice ® Podcast Episode 274, pronunciation series episode 30 (citalopram and escitalopram) The Pharmacist's Voice ® Podcast Episode 272, pronunciation series episode 29 (losartan) The Pharmacist's Voice Podcast Episode 269, pronunciation series episode 28 (tirzepatide) The Pharmacist's Voice Podcast Episode 267, pronunciation series episode 27 (atorvastatin)  The Pharmacist's Voice Podcast Episode 265, pronunciation series episode 26 (omeprazole) The Pharmacist's Voice Podcast Episode 263, pronunciation series episode 25 (PDE-5 inhibitors) The Pharmacist's Voice Podcast Episode 259, pronunciation series episode 24 (ketorolac) The Pharmacist's Voice ® Podcast episode 254, pronunciation series episode 23 (Paxlovid) The Pharmacist's Voice ® Podcast episode 250, pronunciation series episode 22 (metformin/Glucophage) The Pharmacist's Voice Podcast ® episode 245, pronunciation series episode 21 (naltrexone/Vivitrol) The Pharmacist's Voice ® Podcast episode 240, pronunciation series episode 20 (levalbuterol) The Pharmacist's Voice ® Podcast episode 236, pronunciation series episode 19 (phentermine)  The Pharmacist's Voice ® Podcast episode 228, pronunciation series episode 18 (ezetimibe) The Pharmacist's Voice ® Podcast episode 219, pronunciation series episode 17 (semaglutide) The Pharmacist's Voice ® Podcast episode 215, pronunciation series episode 16 (mifepristone and misoprostol) The Pharmacist's Voice ® Podcast episode 211, pronunciation series episode 15 (Humira®) The Pharmacist's Voice ® Podcast episode 202, pronunciation series episode 14 (SMZ-TMP) The Pharmacist's Voice ® Podcast episode 198, pronunciation series episode 13 (carisoprodol) The Pharmacist's Voice ® Podcast episode 194, pronunciation series episode 12 (tianeptine) The Pharmacist's Voice ® Podcast episode 188, pronunciation series episode 11 (insulin icodec)  The Pharmacist's Voice ® Podcast episode 184, pronunciation series episode 10 (phenytoin and isotretinoin) The Pharmacist's Voice ® Podcast episode 180, pronunciation series episode 9 Apretude® (cabotegravir) The Pharmacist's Voice ® Podcast episode 177, pronunciation series episode 8 (metoprolol)  The Pharmacist's Voice ® Podcast episode 164, pronunciation series episode 7 (levetiracetam) The Pharmacist's Voice ® Podcast episode 159, pronunciation series episode 6 (talimogene laherparepvec or T-VEC)  The Pharmacist's Voice ® Podcast episode 155, pronunciation series episode 5 Trulicity® (dulaglutide)  The Pharmacist's Voice ® Podcast episode 148, pronunciation series episode 4 Besponsa® (inotuzumab ozogamicin) The Pharmacist's Voice ® Podcast episode 142, pronunciation series episode 3 Zolmitriptan and Zokinvy The Pharmacist's Voice ® Podcast episode 138, pronunciation series episode 2 Molnupiravir and Taltz The Pharmacist's Voice ® Podcast episode 134, pronunciation series episode 1 Eszopiclone and Qulipta   Kim's websites and social media links: ✅ Guest Application Form (The Pharmacist's Voice Podcast) https://bit.ly/41iGogX ✅ Monthly email newsletter sign-up link https://bit.ly/3AHJIaF  ✅ LinkedIn Newsletter link https://bit.ly/40VmV5B ✅ Business website https://www.thepharmacistsvoice.com ✅ Buy my book and/or audiobook about podcasting on Amazon Pharmacist Podcaster ✅ The Pharmacist's Voice ® Podcast https://www.thepharmacistsvoice.com/podcast ✅ Drug pronunciation course https://www.kimnewlove.com/pronunciations  ✅ Podcasting course https://www.kimnewlove.com/podcasting  ✅ LinkedIn https://www.linkedin.com/in/kimnewlove ✅ Facebook https://www.facebook.com/kim.newlove.96 ✅ Twitter https://twitter.com/KimNewloveVO ✅ Instagram https://www.instagram.com/kimnewlovevo/ ✅ YouTube https://www.youtube.com/channel/UCA3UyhNBi9CCqIMP8t1wRZQ ✅ ACX (Audiobook Narrator Profile) https://www.acx.com/narrator?p=A10FSORRTANJ4Z ✅ Start a podcast with my coach, Dave Jackson from The School of Podcasting! *New 12-4-25* Click my affiliate link: https://community.schoolofpodcasting.com/invitation?code=G43D3G    Thank you for listening to episode 374 of The Pharmacist's Voice ® Podcast. If you know someone who would like this episode, please share it with them!   List of drugs yet to be covered Abciximab Acetazolamide Adapalene Amoxicillin Aripiprazole Carbamazepine Celecoxib Clonazepam Colchicine Cyanocobalamin Dextroamphetamine Diazepam Diltiazem Divalproex Docusate sodium Duloxetine Estradiol Fluoxetine Gabapentin Gemfibrozil Hydralazine Hydrochlorothiazide Hydroxychloroquine sulfate Hydroxyzine HCl (Atarax) Hydroxyzine pamoate (Vistaril) Ibuprofen Ketotifen Levocetirizine Linagliptin Metoclopramide Methylprednisolone Morphine Mupirocin Nortriptyline Oxybutynin Oxycodone Paroxetine Phenazopyridine Phytonadione Polyethylene glycol 3350 Pramipexole Pregabalin Rabeprazole Risperidone Ropinirole Salmeterol/fluticasone in combination Saxagliptin Sertraline Sevelamer Sucralfate Tramadol Trazodone

John Maytham speaks to Taran Eagar about her extraordinary journey from drug mule to drug boss, what led her into the international drug trade, and her new book, From Drug Mule to Drug Boss. Presenter John Maytham is an actor and author-turned-talk radio veteran and seasoned journalist. His show serves a round-up of local and international news coupled with the latest in business, sport, traffic and weather. The host’s eclectic interests mean the program often surprises the audience with intriguing book reviews and inspiring interviews profiling artists. A daily highlight is Rapid Fire, just after 5:30pm. CapeTalk fans call in, to stump the presenter with their general knowledge questions. Another firm favourite is the humorous Thursday crossing with award-winning journalist Rebecca Davis, called “Plan B”. Thank you for listening to a podcast from Afternoon Drive with John Maytham Listen live on Primedia+ weekdays from 15:00 and 18:00 (SA Time) to Afternoon Drive with John Maytham broadcast on CapeTalk https://buff.ly/NnFM3Nk For more from the show go to https://buff.ly/BSFy4Cn or find all the catch-up podcasts here https://buff.ly/n8nWt4x Subscribe to the CapeTalk Daily and Weekly Newsletters https://buff.ly/sbvVZD5 Follow us on social media: CapeTalk on Facebook: https://www.facebook.com/CapeTalk CapeTalk on TikTok: https://www.tiktok.com/@capetalk CapeTalk on Instagram: https://www.instagram.com/ CapeTalk on X: https://x.com/CapeTalk See omnystudio.com/listener for privacy information.

The Big Five is the quintessential Montreal podcast, and the best way to get caught up on the top stories impacting the city. Every weekday, host Elias Makos and a roster of Montreal thought leaders debate and inform. On today's Big 5: Dan Delmar, independent political analyst, media strategist, and co-founder of TNKR Media, and Andrew Caddell, columnist for the Hill Times and President of the Task Force on Linguistic Policy. On the fifth annual National Day for Truth and Reconciliation, listeners and panelists clashed over the lack of Indigenous history taught in French public schools while fewer than twenty of ninety-four historic Calls to Action have been completed. Correctional Service Canada announced federal prisons will now distribute safe inhalation and snorting supplies, including paper straws and foil, to reduce overdose risks. Guelph's mayor and university officials are demanding answers after an unsanctioned homecoming street party deteriorated into a violent riot. Trump advisor Peter Navarro ordered Canadian lobbyists to "get the hell out" of the US as Prime Minister Mark Carney warned Canada may escalate the trade war.

Send us Fan MailEurope looks like one market on a map, but try bringing a drug across borders and you quickly learn it behaves like many systems at once. We sit down with Daphne Smyth, a regulatory leader based in Ireland with 35+ years in pharmaceutical regulatory affairs, to unpack a mistake we keep seeing: companies build commercial teams first, then discover they have not built the regulatory pathway needed to launch at all. The result is not just delay, it is avoidable rework in clinical plans, manufacturing set-up, and the evidence story regulators expect.We spend a big part of the conversation on Chinese pharma and Chinese biotech moving into the EU. Daphne shares what surprises new entrants most: EU complexity, the need for the right legal structure, the reality of EMA procedures and committees, and the hard requirement that clinical data must be relevant to European patient populations, standards of care, and comparators. We also talk about ethnic sensitivity, PK/PD bridging, and why “we already developed it in China” can still mean going backwards to add studies. If Europe becomes too restrictive or simply too complicated, we risk blocking genuinely fascinating innovation.We then zoom out to the global drug development playbook: China's scale and integrated biotech hubs, the US venture-driven model, Europe's regulation-led caution, and why Australia keeps showing up as a fast route for early clinical trials. Finally, we lighten things up with a quick quiz on FDA Q2 2026 approvals, including the runaway earning potential of GLP-1 obesity drugs and how much of the quarter is actually oncology.If you enjoy practical regulatory strategy, market entry realities, and how to get medicines from lab to patients, subscribe, share the episode with a colleague, and leave us a review. What is the hardest “hidden rule” you have seen when entering a new healthcare market?Connect with Daphne Smyth on LinkedIn.Support the show________Reach out to Ivanna RosendalJoin the conversation on our LinkedIn pageVisit www.labtolives.com HostsAlexander BoothChiara ChianeseIvanna Rosendal Oshida 

Hey soldier, where you heading? Approachability: 7/10 (Pulpy Vietnam-era zombie drama w more suspense than scares) Content Warnings: Blood/Violence; Drug abuse; Animal Harm/Death; Suspense/Jump scares; Suicide. Next Week's Film RandomHorror9 T-Shirts Hosts: Jeffrey Cranor & Cecil Baldwin (Find more of our work on Welcome to Night Vale) Logo: David Baldwin Random Horror 9 Patreon YouTube, Bluesky, Letterboxd, & Instagram: @RandomHorror9 We are part of Night Vale Presents Learn more about your ad choices. Visit megaphone.fm/adchoices

Simon and Rachel speak to David Walsh, chief sports writer at the Sunday Times. David began his career reporting for the Leitrim Observer in Ireland and at the age of 25 he became the editor. His next job was at the Dublin-based newspaper the Irish Press, and while working there he decided to take a year out to cover cycling in Paris. He returned to his job for a short period before moving on to the Sunday Tribune followed by the Sunday Independent, and in 1996 he joined the Sunday Times. In 2012 he wrote "Seven Deadly Sins", the story of his 13-year pursuit of the cycling drug cheat Lance Armstrong, which played out on the pages of the Sunday Times and ended in a Hollywood movie, "The Program" in 2015. David's other books include "Inside Team Sky" and "The Russian Affair" and he has won Sports Writer of the Year four times at the Press Awards.  We spoke to David about deciding he wanted to be a sports journalist at the age of six, his investigation into Lance Armstrong, and covering brain injuries in rugby and other sports.  In addition to the standard audio format, the podcast is now available in video. You can check us out on YouTube under Always Take Notes.     We've also made (yet) another update for those ⁠⁠⁠⁠⁠⁠⁠⁠who support the podcast on the crowdfunding site Patreon⁠⁠⁠⁠⁠⁠⁠⁠. We've added a further 70 pages of new material to the package of successful article pitches that goes to anyone who supports the show with $5 per month or more, including new pitches to the New Yorker, Bloomberg Businessweek, and the Guardian Long Read. The whole compendium now runs to a magisterial 230 pages. For Patreons who contribute $10/month we're now also releasing bonus mini-episodes. Other Patreon rewards include signed copies of the podcast book and the opportunity to take part in a call with Simon and Rachel.A new edition of “Always Take Notes: Advice From Some Of The World's Greatest Writers” - a book drawing on our podcast interviews - is available now. The updated version now includes insights from over 100 past guests on the podcast, with new contributions from Harlan Coben, Victoria Hislop, Lee Child, Megan Nolan, Jhumpa Lahiri, Philippa Gregory, Jo Nesbø, Paul Theroux, Hisham Matar and Bettany Hughes. You can order it via ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Amazon⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ or ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Waterstones⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.  Learn more about your ad choices. Visit podcastchoices.com/adchoices

The DTB podcast returns with a new format, and a new host: Dr. Hannah Harris, urgent care GP and now Clinical Editor of DTB.   In this episode, Hannah is joined by Professor Barbara Mintzes and Carol Devine, a patient and second-generation victim of Diethylstilbestrol (DES), to examine the long-term, multigenerational impacts of this synthetic oestrogen prescribed in pregnancy to prevent miscarriage from the 1940s to 1980s. They discuss why DES continued to be prescribed despite early proof of inefficacy and harm, Carol's personal health struggle as a "DES Daughter," and the ongoing fight for government recognition and patient care.     This episode also highlights key clinical updates from the September issue of the Drug and Therapeutics Bulletin, including a commentary by the new Editor-in-Chief, Dr. Gordon Mallarkey, on precision medicine in COPD, non-hormonal treatments for polyendocrine metabolic ovarian syndrome, diagnosis of spasticity, and continuous glucose monitoring in type 2 diabetes.   Read the issue on our website: https://dtb.bmj.com/content/64/9.   We would love to hear from you with comments or questions via email (dtb@bmj.com), or you can find us on X with the handle @DTB_BMJ, and also LinkedIn and Facebook under “Pharmacy at BMJ Group”.   The DTB Podcast is hosted by Hannah Harris. It is produced by Hannah Harris and Letícia Amorim. It is edited by Letícia Amorim.

It was breakfast for supper on Marcus Lush Nights as callers discussed good old fashioned cooked breakfasts and coffee. Marcus and listeners specifically looked back to meat dishes like lambs fry, black pudding, haggis, and more. LISTEN ABOVESee omnystudio.com/listener for privacy information.

View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter Lloyd B. Klickstein is a physician-scientist who has spent more than 20 years at the intersection of drug discovery, healthy aging, and preventive medicine. Drawing on his experience in academic medicine, translational research, and biotechnology, Lloyd walks through the full arc of modern drug development. He explains how scientists identify an unmet medical need and decide which diseases and therapeutic targets are worth pursuing. From there, he takes us through the process of engineering a drug, testing it in animals, and navigating clinical trials and regulatory approval. Using bimagrumab as a case study, Lloyd explains the rationale for targeting myostatin and activin signaling to increase muscle mass and strength and describes how the antibody was engineered and screened. He then walks through what was learned from early clinical trials. Unexpected effects on fat mass and type 2 diabetes helped reshape bimagrumab's development as a potential treatment for obesity, including its use in combination with semaglutide. Along the way, Peter and Lloyd explore the differences among drug modalities, including biologics and small-molecule therapeutics. They discuss the roles of patents and capital allocation in drug development, along with the requirements for IND submission and GMP manufacturing. They also examine why developing a new drug takes so long and costs so much, and why identifying failures early is critical. At the end of the episode, the conversation turns to mTOR inhibition and geroprotection, as well as Lloyd's current work on a novel pharmacologic approach to cancer prevention. This episode provides a rare behind-the-scenes look at how new medicines are actually created and the scientific, regulatory, and economic decisions that determine which ideas ultimately make it to patients. We discuss: Lloyd's path from academic medicine to translational drug development [3:15]; Drug modalities, patents, and the economics of innovation [11:30]; Choosing sarcopenia as a target for drug development, and confronting the problem of measuring falls [23:00]; The rationale for bimagrumab: improving muscle mass and strength by targeting myostatin and activin signaling (and why follistatin failed) [36:45]; Engineering and screening the bimagrumab antibody, and the cost of developing a new drug [43:45]; From candidate antibodies to animal proof of concept (impressive muscle hypertrophy) [54:15]; Toxicology, capital allocation, and the path to an IND [1:02:45]; IND requirements, GMP manufacturing, and gray market peptides [1:14:45]; First in-human study design, patient selection, and protection of healthy volunteers [1:22:00]; Phase 1 dosing, pharmacodynamics, and global trial strategy [1:33:45]; Phase 2 lessons on muscle mass, function, and nutrition [1:43:30]; Bimagrumab's effects on fat mass and type 2 diabetes [1:50:45]; The BELIEVE trial of bimagrumab plus semaglutide [1:59:30]; Selective mTORC1 inhibition and the challenge of testing geroprotection [2:11:45]; A new pharmacologic approach to cancer prevention [2:15:45]; and More. Connect With Peter on Twitter, Instagram, Facebook and YouTube

**The Clay Edwards Show – Ep. 1303**   Co-host: Creston Berch Clay overslept Friday. Body finally called timeout after two weeks of four-hour nights. Chip and Creston held it down. Today we catch up and then some. Ole Miss walked into the perfect letdown game at Florida and got stomped. Defense still can't stop the run. They're sitting ninth in the AP, 12th in the coaches poll with an open date then Vandy. State looks legit, 16th in the coaches poll, Alabama coming to Starkville. Rankings are still living in last year. First month of the season should move. It isn't. Clay vs Grok week four: Clay 17-9 ATS + totals on the 10-12 best games (plus the Mississippi ones). Grok 15-11. Season: Clay still beating the computer. Emotion and letdown spots still matter more than last year's recruiting rankings. That'll flip once the data pile gets bigger. We'll see. Ellis Autoplex question of the day: pinpoint the exact moment society got substantially worse. Answers poured in — COVID, Great Society, parents asking kids what they want for dinner, Obama, prayer and discipline leaving schools. Locally Clay's line is Harvey Johnson telling Caterpillar/Puckett/Stribling to kick rocks on the drainage work at Lynch & 80. Anchor tenant leaves, corridor dies, wave rolls east and west. You cannot pay for a city with housetops. Then the Ben Crump / Christine Wansley circus. Thursday's press conference was half-truths and open-ended “facts” designed for you to fill in the horror movie. Snapchats were deleted — by other people in the group chat, which is how the app works. Phone left on the boat because he was standing in four feet of water and service sucks at the island. No blunt force trauma in any report. Red discoloration. Dry drowning explains empty lungs and stomach: larynx spasms, airway slams shut, no water ever gets in. Simplest explanation is usually the right one. He drowned. The boys are innocent. Crump and Wansley are doing a disservice to Nolan's memory while she globe-trots instead of grieving. Same playbook on Tasia Fortune. Third arrest. Drug debt. Hanging was staged after she was already dead. Sister said she weighed a hundred pounds soaking wet. Third Black face of “white supremacy” in Jackson. Stop inventing lynchings when the culture is eating itself at gas stations. Kamario Taylor says maroon and white. Half the internet immediately assumes he's on the first NIL bus out of Starkville. Let the kid play. Loyalty still exists. Unfiltered. No sugar. Facts over feelings. Same time tomorrow.

Episode 131 of The Wild Chaos Podcast is streaming NOW on YouTube and all major podcast platforms!Watch the full episode here: https://youtu.be/K5wjqC6dY1QFormer Blue Mound, Texas Police Chief Dusty Steele spent roughly 16 years working in bail bonds and bounty hunting before becoming a police officer and eventually chief of police. But some of the biggest battles of his career wouldn't come from fugitives or criminals. They would come from inside the system itself.Dusty sits down with me to tell the story of a career that took him from hunting fugitives through some of Fort Worth's roughest neighborhoods to building the kind of police department he says he always wanted to work for.He breaks down what bounty hunting was really like before reality television turned it into entertainment, including middle-of-the-night fugitive arrests, suspects hiding in attics, violent fights, tracking people through family members and one fugitive who allegedly tried to run him over.Then Dusty's story shifts.After becoming chief of police in Blue Mound, Texas, Dusty says he built a proactive department focused on officer morale, community relationships and aggressive enforcement against local drug activity.But disagreements between Dusty and city leadership eventually emerged over police funding, employee pay, dispatch services and control of department information.On September 15, 2022, Dusty publicly resigned during a city budget hearing as officials considered changes to the police budget and outsourcing dispatch services.In this episode, Dusty gives his account of what happened behind the scenes, why he believed his position had become untenable, what happened after his resignation and why he believes small-town politics can exert enormous influence over law enforcement leadership.Bounty hunting. Fugitive arrests. Police pursuits. Drug houses. Leadership. City politics. Department culture. Retaliation allegations. And the question underneath the entire conversation:Who holds the people at the top accountable?This is Episode 131 of The Wild Chaos Podcast with former Police Chief Dusty Steele.

Jordan Kawchuk has struggled with alcohol use disorder for years. When he's drinking, he says nothing else matters. He's just finished his fifth attempt at treatment, but some doctors and advocates say people like him aren't getting the science-based treatment they need.

Just weeks after securing HSE funding for Skyclarys, Cork dad Craig Cody reveals the devastating bottleneck finding a neurologist to approve a prescription for Skyclarys Hosted on Acast. See acast.com/privacy for more information.

Joshua Philipp, senior investigative reporter at The Epoch Times and host of Crossroads, joins Jiggy Jaguar for an in-depth discussion of America's expanding maritime counter-narcotics operations. The conversation covers recent Eastern Pacific interdictions, separate Caribbean military strikes, alleged cartel connections, Ecuador, fentanyl trafficking, the evidence available publicly and the broader legal and geopolitical questions surrounding military involvement in counter-drug operations. Keywords: Joshua Philipp, Jiggy Jaguar, Epoch Times, drug trafficking, U.S. military, cartels, fentanyl, Latin America, Ecuador, geopolitics, current events #JoshuaPhilipp #JiggyJaguar #Podcast #CurrentEvents

Homeopathy is an alternative medicine made in 1796 by German physician Samuel Hahnemann. Hahnemann believed that substances that caused symptoms of disease in healthy people could provide a cure for the sick. This ideology is called similia similibus curentur, in english this translates to "like cures like.” To create these remedies, practitioners repeatedly dilute the substance in water by shaking it until the final product practically has nothing left of the original substance. It's believed that through this process, the diluent is able to remember and hold the energy of the original substance. At the time of its creation, homeopathy was a safer alternative to common practices like mercury or leeches. However, in today's world of science there are many debates on whether or not these practices are safe or ethical. In today's episode of Health 411, Dr. Jonathan Karp and graduate student producer Iso Rampulla explain the history of homeopathy and the truth behind the placebo effect. They explore the validity of results and why it's important to understand the actual impact of homeopathic treatment inside of relying on it as a sole cure. The two discuss the recent bill, S.4692 - Homeopathic Drug Product Safety, Quality, and Transparency Act, which desires to amend the Federal Food, Drug, and Cosmetic Act for homeopathic drugs and the dangers of it being passed. Tune in to this week's episode of Health 411 to learn more about the history of homeopathy and the impacts it's has on today's world.

Homeopathy is an alternative medicine made in 1796 by German physician Samuel Hahnemann. Hahnemann believed that substances that caused symptoms of disease in healthy people could provide a cure for the sick. This ideology is called similia similibus curentur, in english this translates to "like cures like.” To create these remedies, practitioners repeatedly dilute the substance in water by shaking it until the final product practically has nothing left of the original substance. It's believed that through this process, the diluent is able to remember and hold the energy of the original substance. At the time of its creation, homeopathy was a safer alternative to common practices like mercury or leeches. However, in today's world of science there are many debates on whether or not these practices are safe or ethical. In today's episode of Health 411, Dr. Jonathan Karp and graduate student producer Iso Rampulla explain the history of homeopathy and the truth behind the placebo effect. They explore the validity of results and why it's important to understand the actual impact of homeopathic treatment inside of relying on it as a sole cure. The two discuss the recent bill, S.4692 - Homeopathic Drug Product Safety, Quality, and Transparency Act, which desires to amend the Federal Food, Drug, and Cosmetic Act for homeopathic drugs and the dangers of it being passed. Tune in to this week's episode of Health 411 to learn more about the history of homeopathy and the impacts it's has on today's world.

Broadcast from KSQD, Santa Cruz on 9-24-2026: Dr. Dawn warns about a sophisticated phishing scam arriving by mail impersonating post-hack credit-monitoring services from Kroll—the tell being that clicking through prompts for the same personal information the fake letter claims was already breached. ABT-263, an experimental cancer drug that selectively kills senescent "zombie" cells by blocking their BCL-2 anti-apoptotic proteins, dramatically sped wound healing in aged mice (80% healed by day 24 versus 56% in controls) with no effect on young mice—opening potential applications for chronic wounds, diabetic ulcers, and cosmetic use. Dr. Dawn explains why cooling dulls sweetness but enhances saltiness (via cold-activated epithelial sodium channels)—so under-salt hot dishes and don't judge saltiness while food is piping hot. Dr. Dawn walks through when to get stitches: bleeding that won't stop after 10-15 minutes of pressure, visible fat (yellow bubbles) or muscle, jagged edges that won't zipper together, wounds over joints, animal bites, and puncture wounds, and recommends bacitracin over petroleum jelly for initial dressing due to contamination in commonly-used jars. Researchers created a "spud cell"—a barely-living synthetic organism with just 36 genes (from E. coli, viruses, and jellyfish) that divides five times over 12-hour cycles and needs hand-feeding, potentially opening a path to made-to-order cells for cancer treatment, plastic degradation, and carbon capture. Rezdiffra, an analog of activated thyroid hormone T3 that binds only the beta receptor (avoiding cardiac alpha-receptor toxicity), treats metabolic dysfunction-associated steatotic liver disease (MASLD, now affecting 25-40% of adults globally) by boosting fat breakdown and reversing liver fibrosis in patients where diet, exercise, GLP-1 drugs, and bariatric surgery haven't been enough. UK Biobank data from 355,000 people showed that drinking five or more cups of coffee daily was associated with 32% reduced cirrhosis risk and 47% reduced liver cancer risk over 13 years, along with lower liver fat, iron, fibrosis, and inflammation. Men's average testosterone has fallen 54% over the past half-century (steepening after 2000), largely driven by belly fat's aromatase enzyme converting testosterone to estrogen, with hormone-disrupting chemicals and microwaved plastics as additional suspects. Dr. Dawn revisits the 9/11 exposure legacy—28,000 survivors now receiving compensation for asbestos, benzene, and building-fire toxin exposures linked to breast and prostate cancer—and recommends aggressive fiber intake (aim for two large daily bowel movements) and far-infrared sauna sweating as accessible detoxification tools relevant now for those exposed to current fire-season smoke.

INTRODUCTION:Fever of Unknown Origin, or FUO: We have all had a fever at some point—maybe from seasonal flu or a brief stomach bug—where the body turns up the heat, fights off the bug, and recovers in a couple of days. Fever is a very efficient defense mechanism to fight microorganisms by making your body a hostile environment where they cannot survive. But what happens when a fever lasts for weeks, standard tests come back normal, and usual fever reducing medications do not seem to work?We will talk about the surprising root causes, the latest imaging technology like PET scans, and what to do when a fever refuses to break. Whether you are a medical student, a healthcare professional, or simply curious about how our body's defense mechanisms work, this episode is for you. Let us get into it!Definition of Fever of Unknown Origin.A standard fever is like a smoke alarm going off when you burn toast—you quickly spot the cause, fix it, and the alarm stops. FUO is like an alarm ringing continuously for weeks, but despite searching every room, you cannot find the source of the fire.Clinical Criteria (Classic FUO):1. Temperature >38.3 C measured on multiple occasions.2. Duration of at least 3 weeks.3.Unexplained after 1 week of intensive outpatient or inpatient evaluation (or three outpatient visits).Categories of FUO.1. Classic FUO: The traditional presentation described above.2. Nosocomial (Hospital-Acquired) FUO: Fevers in hospitalized patients without infection upon admission.3. Neutropenic FUO: Fevers in immunocompromised patients (e.g., undergoing chemotherapy) with low white blood cell counts.4. HIV-Associated FUO: Fevers lasting weeks in patients with HIV, often driven by opportunistic infections like Tuberculosis or CMV, that stands for cytomegalovirus. What a mouthful!The Big Four Causes are:Infections (~30–40%): Atypical presentations of common diseases (e.g., hidden abscesses, endocarditis, tuberculosis, or tick-borne illnesses). Our priority will be to determine if this patient is having an infection, unless we get clinical manifestations that would guide us in another direction.Autoimmune & Inflammatory Diseases (~20–30%): The immune system overreacting and attacking the body's tissues (e.g., Adult-onset Still's disease, Temporal Arteritis/Giant Cell Arteritis, Lupus).Malignancies / Cancers (~10–20%): Blood cancers (Lymphoma, Leukemia) or solid tumors (Renal cell carcinoma). Infections, autoimmune/inflammatory diseases, and malignancies cover 60-90% of the causes of FUO.Miscellaneous / Drug Fevers (~10–15%): "Drug fever" caused by adverse reactions to common medications (e.g., antibiotics, anti-seizure meds), thyroid storm, or deep vein thrombosis (DVT).Modern Medicine: Advanced imaging (CT, MRI, PET scans) which have helped us diagnose cancers and abscesses much earlier. As a result, modern FUOs are increasingly driven by autoimmune conditions, non-infectious inflammatory disorders. Sometimes it feels like we solve one problem and uncover another one!Important: Some cases remain undiagnosed (up to 30–50%) and resolve without a specific label.Diagnostic Approach:Step 1: The "Detective Work" (History & Physical):● Detailed History: Travel history, animal exposure (ticks, pets), occupational hazards, social history, medication review (to exclude drug fevers), and family history.● Potential Diagnostic Clues: Looking for subtle signals (e.g., a new heart murmur, temporal tenderness, hidden skin rashes, or swollen lymph nodes).Step 2: Basic Tiered Testing:● Blood Work: CBC (complete blood count), inflammatory markers (ESR, CRP, Ferritin), comprehensive metabolic panel, blood cultures.● Targeted Serologies: HIV, viral panels, autoimmune antibodies (ANA, Rheumatoid Factor).● Initial Imaging: Chest X-ray, abdominal ultrasound.Step 3: Advanced Diagnostic Workup:FDG-PET/CT Imaging: One of the most significant updates in recent guidelines. FDG-PET/CT uses a radioactive sugar tracer to highlight areas of high metabolic activity (inflammation, infection, tumor) throughout the entire body in a single scan. FDG-PET is a functional nuclear-imaging technique that uses ¹⁸F-fluoro-deoxy-glucose (FDG) — a radioactive glucose analog — to map tissue glucose metabolism.Targeted Biopsies: Biopsying tissues guided by PET scan findings (e.g., lymph node, liver, or temporal artery)."Refractory" Fevers:Fever vs. Hyperthermia: Standard fevers are driven by the brain's hypothalamus resetting the body's thermostat upward (often mediated by prostaglandins). ● Antipyretics (acetaminophen, NSAIDs) block prostaglandin synthesis.● If a fever does not respond to antipyretics, it may indicate non-prostaglandin-mediated inflammation (e.g., severe cytokine storm, drug-induced hyperthermia, or central nervous system dysregulation).Empiric Treatment vs. Observation:● The "Hold Your Horses" Principle: Current guidelines strongly advise against starting empirical antibiotics or steroids right away in stable patients. Antibiotics can mask infections and produce false-negative culture results, while steroids can hide inflammatory signs or exacerbate hidden infections.● When to Treat Empirically: Reserved for hemodynamically unstable patients, neutropenic patients, or specific high-suspicion conditions (e.g., suspected Temporal Arteritis to prevent blindness).Diagnostic Trial: Naproxen Test (Historical & Clinical Pearl): A brief trial of naproxen can sometimes distinguish tumor fevers (which often drop sharply in response to NSAIDs) from infectious fevers, though it is used cautiously as a supportive diagnostic clue rather than a rule. So, if a patient responds to a trial of naproxen, then we can suspect a tumor as a cause of the patient's fevers. But it is not a strong recommendation.A 2019 systematic review/meta-analysis (15 studies, 582 patients) found a 94.1% success rate for naproxen in treating confirmed neoplastic fever. The test is not specific and lacks validation, but I can see the importance of knowing this: Naproxen is effective against cancer fever.FUO evaluation is a marathon, not a sprint. Re-evaluating the patient daily in the hospital for new physical clues is often more valuable than ordering endless specialized tests. I would like to emphasize that modern tools PET/CT have transformed how quickly we locate hidden inflammation. Also, let us remember that a huge proportion of undiagnosed FUOs eventually resolve spontaneously with good long-term outcomes, provided serious conditions have been systematically ruled out.Take away messages:First, FUO is a diagnostic marathon, not a sprint. Finding the cause takes patient detective work, careful daily exams, and targeted testing rather than rushing into quick fixes.Second, modern imaging like FDG-PET scans has completely transformed how we spot hidden inflammation and infection long before standard blood work gives us an answer.And finally, 'refractory' fevers require caution. If a fever is not responding to standard antipyretics, starting antibiotics or steroids right away can hide the real culprit. In stable patients, holding off and continuing the search is often the safest path.__________________Even without trying, every night you go to bed a little wiser. Thanks for listening to Rio Bravo qWeek Podcast. We want to hear from you, send us an email at RioBravoqWeek@clinicasierravista.org, or visit our website riobravofmrp.org/qweek. See you next week!References:1) David AB, Quinlan JD. Fever of Unknown Origin in Adults. American Family Physician. 2022;105(2):137-143.2) Wright WF, Stelmash L, Betrains A, Mulders-Manders CM, Rovers CP, Vanderschueren S, Auwaerter PG; International Fever and Inflammation of Unknown Origin Research Working Group. Recommendations for Updating Fever and Inflammation of Unknown Origin From a Modified Delphi Consensus Panel. Open Forum Infectious Diseases. 2024;11(7):ofae298.3) Wright WF, Durso SC, Forry C, Rovers CP. Fever of unknown origin. BMJ. 2025;388:e080847.4) Wright WF, Auwaerter PG. Fever and fever of unknown origin: review, recent advances, and lingering dogma. Open Forum Infectious Diseases. 2020;7(5):ofaa132.5) Cunha BA, Lortholary O, Cunha CB. Fever of unknown origin: a clinical approach. The American Journal of Medicine. 2015;128(10):1138.e1-1138.e15.6) Nazar AH, Naswa N, Sharma P, et al. Spectrum of 18F-FDG PET/CT findings in patients presenting with fever of unknown origin. American Journal of Roentgenology. 2012;199(1):175-1851) Theme song, Works All The Time by Dominik Schwarzer, YouTube ID: CUBDNERZU8HXUHBS, purchased from https://www.premiumbeat.com/. Even without trying, every night you go to bed a little wiser. Thanks for listening to Rio Bravo qWeek Podcast. We want to hear from you, send us an email at RioBravoqWeek@clinicasierravista.org, or visit our website riobravofmrp.org/qweek. See you next week!

Mississippi police now say that a woman found hanged likely was staged after her killing. AP's Lisa Dwyer reports.

It's the day before the pain boards, so Dr. David Rosenblum skipped the Zoom and recorded a rapid-fire, last-minute review of the high-yield keywords and "board traps" most likely to show up on the ABA Pain Medicine exam. Listen on your commute or at the gym. High-yield topics covered Neonatal pain: A-delta and C fibers and ascending pathways work before birth, but descending inhibition is immature, so neonatal pain may be exaggerated or prolonged. Board trap: incomplete myelination does not mean neonates can't feel pain. Dorsal horn anatomy: Rexed laminae I, II and V. Lamina II is the substantia gelatinosa. Peripheral vs. central sensitization: the "inflammatory soup" (prostaglandins, bradykinin, H+, ATP, histamine, serotonin, cytokines, NGF) causes primary hyperalgesia. NMDA activation, wind-up and expanded receptive fields cause secondary hyperalgesia and allodynia. Superficial cervical plexus (C2–C4): lesser occipital, great auricular, transverse cervical and supraclavicular nerves. Blocked behind the SCM, and useful for clavicle pain. Eagle syndrome: an elongated styloid process irritating the glossopharyngeal nerve. Pain scales: NIPS, CRIES, FLACC and modified FLACC, Wong-Baker FACES, FPS-R, NRS, VAS and PROMIS-10 Global Health. Statistics: sensitivity and specificity don't depend on prevalence, but PPV and NPV do. Type I error is a false positive (α = 0.05) and Type II error is a false negative. Acetaminophen toxicity: use the Rumack-Matthew nomogram at 4 hours or later (acute single ingestion only). N-acetylcysteine is the antidote. Buprenorphine: a high-affinity partial mu agonist and kappa antagonist, with a ceiling effect on respiratory depression. Drug toxicities: carbamazepine (SIADH, SJS with HLA-B*1502, CYP3A4 induction), methotrexate (leucovorin rescue), hydroxychloroquine (retina), TNF-α inhibitors (TB reactivation), JAK inhibitors (boxed warning for MACE, thrombosis, malignancy), NSAIDs, SSRIs/SNRIs and tramadol (hyponatremia). Muscle relaxants: baclofen, tizanidine, cyclobenzaprine, methocarbamol, metaxalone, carisoprodol (meprobamate), chlorzoxazone, dantrolene, diazepam and botulinum toxin (cleaves SNARE proteins). Upcoming events Coming up: the NY/NJ Pain Congress in November and the Latin American Pain Society meeting next year. Hands-on NRAP ultrasound courses in New York are coming up in October and November. See the calendar at nrappain.org. Taking the boards next year? Start here: More CME, board review and ultrasound training at www.NRAPpain.org. Patients: in pain in Brooklyn or NYC? Dr. Rosenblum treats patients with back, neck, joint and nerve pain in Brooklyn, NY, and offers virtual second opinions. Visit RosenblumPain.com or call (718) 436-7246 to book an appointment. For educational purposes only. Not medical advice.

It's the day before the pain boards, so Dr. David Rosenblum skipped the Zoom and recorded a rapid-fire, last-minute review of the high-yield keywords and "board traps" most likely to show up on the ABA Pain Medicine exam. Listen on your commute or at the gym. High-yield topics covered Neonatal pain: A-delta and C fibers and ascending pathways work before birth, but descending inhibition is immature, so neonatal pain may be exaggerated or prolonged. Board trap: incomplete myelination does not mean neonates can't feel pain. Dorsal horn anatomy: Rexed laminae I, II and V. Lamina II is the substantia gelatinosa. Peripheral vs. central sensitization: the "inflammatory soup" (prostaglandins, bradykinin, H+, ATP, histamine, serotonin, cytokines, NGF) causes primary hyperalgesia. NMDA activation, wind-up and expanded receptive fields cause secondary hyperalgesia and allodynia. Superficial cervical plexus (C2–C4): lesser occipital, great auricular, transverse cervical and supraclavicular nerves. Blocked behind the SCM, and useful for clavicle pain. Eagle syndrome: an elongated styloid process irritating the glossopharyngeal nerve. Pain scales: NIPS, CRIES, FLACC and modified FLACC, Wong-Baker FACES, FPS-R, NRS, VAS and PROMIS-10 Global Health. Statistics: sensitivity and specificity don't depend on prevalence, but PPV and NPV do. Type I error is a false positive (α = 0.05) and Type II error is a false negative. Acetaminophen toxicity: use the Rumack-Matthew nomogram at 4 hours or later (acute single ingestion only). N-acetylcysteine is the antidote. Buprenorphine: a high-affinity partial mu agonist and kappa antagonist, with a ceiling effect on respiratory depression. Drug toxicities: carbamazepine (SIADH, SJS with HLA-B*1502, CYP3A4 induction), methotrexate (leucovorin rescue), hydroxychloroquine (retina), TNF-α inhibitors (TB reactivation), JAK inhibitors (boxed warning for MACE, thrombosis, malignancy), NSAIDs, SSRIs/SNRIs and tramadol (hyponatremia). Muscle relaxants: baclofen, tizanidine, cyclobenzaprine, methocarbamol, metaxalone, carisoprodol (meprobamate), chlorzoxazone, dantrolene, diazepam and botulinum toxin (cleaves SNARE proteins). Upcoming events Coming up: the NY/NJ Pain Congress in November and the Latin American Pain Society meeting next year. Hands-on NRAP ultrasound courses in New York are coming up in October and November. See the calendar at nrappain.org. Taking the boards next year? Start here: More CME, board review and ultrasound training at www.NRAPpain.org. Patients: in pain in Brooklyn or NYC? Dr. Rosenblum treats patients with back, neck, joint and nerve pain in Brooklyn, NY, and offers virtual second opinions. Visit RosenblumPain.com or call (718) 436-7246 to book an appointment. For educational purposes only. Not medical advice.

It's the day before the pain boards, so Dr. David Rosenblum skipped the Zoom and recorded a rapid-fire, last-minute review of the high-yield keywords and "board traps" most likely to show up on the ABA Pain Medicine exam. Listen on your commute or at the gym. High-yield topics covered Neonatal pain: A-delta and C fibers and ascending pathways work before birth, but descending inhibition is immature, so neonatal pain may be exaggerated or prolonged. Board trap: incomplete myelination does not mean neonates can't feel pain. Dorsal horn anatomy: Rexed laminae I, II and V. Lamina II is the substantia gelatinosa. Peripheral vs. central sensitization: the "inflammatory soup" (prostaglandins, bradykinin, H+, ATP, histamine, serotonin, cytokines, NGF) causes primary hyperalgesia. NMDA activation, wind-up and expanded receptive fields cause secondary hyperalgesia and allodynia. Superficial cervical plexus (C2–C4): lesser occipital, great auricular, transverse cervical and supraclavicular nerves. Blocked behind the SCM, and useful for clavicle pain. Eagle syndrome: an elongated styloid process irritating the glossopharyngeal nerve. Pain scales: NIPS, CRIES, FLACC and modified FLACC, Wong-Baker FACES, FPS-R, NRS, VAS and PROMIS-10 Global Health. Statistics: sensitivity and specificity don't depend on prevalence, but PPV and NPV do. Type I error is a false positive (α = 0.05) and Type II error is a false negative. Acetaminophen toxicity: use the Rumack-Matthew nomogram at 4 hours or later (acute single ingestion only). N-acetylcysteine is the antidote. Buprenorphine: a high-affinity partial mu agonist and kappa antagonist, with a ceiling effect on respiratory depression. Drug toxicities: carbamazepine (SIADH, SJS with HLA-B*1502, CYP3A4 induction), methotrexate (leucovorin rescue), hydroxychloroquine (retina), TNF-α inhibitors (TB reactivation), JAK inhibitors (boxed warning for MACE, thrombosis, malignancy), NSAIDs, SSRIs/SNRIs and tramadol (hyponatremia). Muscle relaxants: baclofen, tizanidine, cyclobenzaprine, methocarbamol, metaxalone, carisoprodol (meprobamate), chlorzoxazone, dantrolene, diazepam and botulinum toxin (cleaves SNARE proteins). Upcoming events Coming up: the NY/NJ Pain Congress in November and the Latin American Pain Society meeting next year. Hands-on NRAP ultrasound courses in New York are coming up in October and November. See the calendar at nrappain.org. Taking the boards next year? Start here: More CME, board review and ultrasound training at www.NRAPpain.org. Patients: in pain in Brooklyn or NYC? Dr. Rosenblum treats patients with back, neck, joint and nerve pain in Brooklyn, NY, and offers virtual second opinions. Visit RosenblumPain.com or call (718) 436-7246 to book an appointment. For educational purposes only. Not medical advice.

EP 744 Jailbreak Tools Hidden in Rice, Drug Arrest & KSh7.2M Bhang Bust: Atwoli Family Cremation story

From Lab to Startup: How Technology Is Changing the Future of Healthcare With Chris Yoo of Xcellerant Ventures AZ TRT S07 EP16 (298) 9-20/2027 What  We Learned This Week A Startup Is More Than an Idea A great idea is only the starting point. Investors also look at the founder, team, execution, market, technology and ability to adapt. Idea → Team → Execution → Business New Jetstream Fund for the average Investor. Venture Capital Is About De-Risking Early-stage investing isn't about eliminating uncertainty. It's about progressively reducing it. Research creates information. Information creates validation. Validation reduces risk. Technology Is Compressing the Timeline of Healthcare Innovation Genomics, sequencing, AI and computing are allowing researchers to perform certain processes dramatically faster and cheaper than in the past. That creates opportunities to move discoveries from the laboratory toward actual medical applications. Arizona Has a Growing Technology-to-Enterprise Pipeline Arizona's technology ecosystem isn't just startups. It includes: Universities → Research → IP → Entrepreneurs → Capital → Companies → Commercialization The universities and research institutions are important pieces of that pipeline. The Next Healthcare Revolution May Come From Data The conversation around genomics, eye scans, AI and precision medicine points toward a broader change: The human body is becoming a source of increasingly usable data. The opportunity is to turn that data into better diagnosis, more personalized treatment and potentially earlier prevention.     AZ Tech Show Notes — Chris Yoo, Xcellerant Ventures September 2026 Guest: Chris Yoo, PhD Organization: Xcellerant Ventures Website: https://www.xcellerantventures.com/ Jetstream Fund: https://www.jvf.vc/ WHY VENTURE CAPITAL? Venture capital is where tomorrow's wealth is created. For decades, venture capital has been among the strongest-performing asset classes for long-term investors. Invest in Tomorrow's Transformation   Xcellerant Ventures is a venture capital company that invests in technologies that power the future of healthcare by providing solutions that improve quality, efficiency, access, and delivery of care at lowered costs.   We lead with a people first philosophy. When we put our knowledge, power, and experience into people, we empower entrepreneurs to change the world for the better.   Bio Dr. Chris Yoo is not only a successful entrepreneur; he's an innovative visionary within the healthcare and life science startup ecosystem. With over 25 years of experience, Chris is building companies and the very foundation upon which future breakthroughs are made. Chris accomplishes this through his unique blend of scientific expertise, entrepreneurial acumen, and a deep commitment to fostering collaborative ecosystems.   As a serial entrepreneur, Chris consistently bridges the gap between cutting-edge science and impactful solutions. From co-founding Systems Imagination, a pioneer in AI for drug discovery, to shaping the future of cancer treatment with Systems Oncology, his ventures consistently champion disruptive technologies. Beyond these ventures, Chris' track record speaks volumes. He successfully founded and exited ventures including MedTrust Online, the world's first online cancer doctor community, TransMed Partners, the first boutique consultancy for translational medicine, and LabBook, the pioneering electronic lab notebook. His ability to not only identify these innovations but also shepherd them towards successful application solidifies Chris' position as a leader at the forefront of the bioscience revolution.   Partners:   John Shufeldt, MD, JD, MBA, FACEP General Partner ·         BA, Sociology and Criminology: Drake University ·         MD: The Rosalind Franklin School of Medicine & Science ·         MBA, JD, & Six Sigma Black Belt: Arizona State University ·         Certificate in Entrepreneurism and Innovation: Harvard ·         Certificate in AI: Massachusetts Institute of Technology   Douglas (Doug) Sylvester, JD, LLM General Partner ·         BA, University of Toronto ·         JD, University of Buffalo School of Law ·         LLM, New York University School of Law   Michael Shufeldt, MBA General Partner ·         BS, International/Global Studies, University of Arizona ·         MBA, Arizona State University   Focus: Technology, healthcare, life sciences, biotech, startups and early-stage investing Episode Overview Chris Yoo brings a unique perspective to the Arizona technology ecosystem, combining a background in cell biology and healthcare with venture capital and startup investing. With a PhD in cell biology from Yale, Chris has spent much of his career thinking about fundamental questions in medicine: Why do people get diseases? How can we diagnose them? And how can we develop better treatments? Today, through Xcellerant Ventures and the Jetstream Fund, he works with founders developing technologies in healthcare, life sciences, biotech and other emerging technology sectors. A major theme throughout the conversation was de-risking — taking something that is unknown and making it less unknown through research, data, testing, execution and commercialization.   Segment 1 — What Makes a Startup Investable? Startup ≠ Just a Great Idea A startup begins with an idea, but venture investors aren't simply investing in ideas. They are evaluating: The founder The team The market The technology The ability to execute The company's strategy The company's ability to adapt Chris emphasized the importance of the founder/funder relationship. The founder may have the original vision, but the company will evolve considerably as it moves from an idea toward a real business. Founder vs. Idea Chris is less concerned about whether a company has: One founder, or A founding team What matters is whether the people involved have clearly defined roles and responsibilities and whether those roles fit their individual strengths. A startup eventually needs expertise in areas such as: Engineering Sales Marketing Operations Product development Finance Those needs change as the company grows. The Founder's Dilemma One of the challenges for founders is recognizing that the company changes as it grows. The person who is perfect for getting a company from zero to one may not necessarily be the person who should manage every function when the company becomes much larger. The company needs to evolve. Different Stages Require Different Capital Chris discussed the distinction between different stages of startup funding. For example: Pre-seed → Seed → Early Growth → Later Stage And there is an important distinction between: Pre-revenue and pre-seed. A company can be extremely early while still having different levels of valuation, technology development and market evidence. De-Risking One of the most important venture capital concepts from the conversation: De-risking means making unknowns less unknown. Investors don't expect every question to be answered at the beginning. Instead, they want to see progress: Unknown → Research → Data → Validation → Commercialization Each stage provides more information and reduces uncertainty. Segment 2 — From Cell Biology to Technology Chris's background starts in healthcare and life sciences. He earned his PhD in Cell Biology from Yale, studying fundamental questions around disease: Why do diseases happen? How can they be diagnosed? How can they be treated? That scientific background influences how he approaches startups today. Think Critically About Problems A recurring theme was the importance of thinking critically about the actual problem before jumping to the solution. Technology creates new possibilities, but the technology still has to solve a meaningful problem. Technology Has Accelerated Healthcare The growth of computing, data, genomics and sequencing has dramatically accelerated life-science research. Processes that once took: Months Millions of dollars $ Large teams can now sometimes be completed in: Days At dramatically lower costs With significantly more data Genomic sequencing is one example. The cost and speed of sequencing have changed dramatically over the past several decades. Technology + Life Sciences Chris sees enormous potential where technology intersects with biology. Examples include: Genomics Gene sequencing Artificial intelligence Cell therapies Data analysis Precision medicine Drug development The goal isn't technology for technology's sake. The goal is ultimately to translate technology into medicine. From General Treatment to Personalized Treatment One of the biggest possibilities is moving toward treatments that are increasingly tailored to the individual patient. Instead of simply asking: "What drug treats this disease?" the question becomes: "What treatment is most appropriate for this particular patient?" That shift could fundamentally change medicine. Segment 3 — Arizona's Technology & Life Sciences Ecosystem Xcellerant Ventures focuses heavily on Arizona companies, particularly in: Healthcare Life sciences Biotechnology Technology Military/defense applications Dual-use technologies The Xcellerant team brings multiple areas of expertise to the table. Chris has the scientific background, while partners bring expertise in areas such as medicine and intellectual property. More Than Just Money A venture investor can provide founders with more than capital. They can bring: Industry knowledge Scientific expertise Operating experience Networks Business models Strategic guidance Commercialization expertise The objective is to help founders move from technology to enterprise. Arizona's Ecosystem Chris emphasized that Arizona has a much larger technology and life-sciences ecosystem than many people realize. Universities and research institutions play an important role. Organizations and institutions mentioned during the conversation included: Arizona State University University of Arizona ASU's medical programs Grand Canyon University University technology commercialization programs UA Tech Launch GC Ventures The Flinn Foundation Universities serve as important sources of: Research → Innovation → Intellectual Property → Companies An Example: Eye Technology Chris discussed Mu Medical, a Minnesota company developing a highly precise eye-drop delivery device called the NanoDropper. The company is led by a medical doctor, Elisa Song, and has a small founding team. Website: https://www.mumedical.com/   The broader opportunity involves oculomics — using information from the eye to learn more about a person's overall health. The eye can potentially provide biological information that extends well beyond traditional eye diseases. Segment 4 — The Eye as a Window Into Health One of the most interesting concepts discussed was the growing ability to use eye scans and imaging data to identify patterns associated with broader health conditions. Think about the progression: Eye image → Data → Pattern recognition → AI → Diagnosis/Prediction → Treatment/Prevention The opportunity goes beyond traditional eye conditions such as glaucoma. Chris compared the growing understanding of eye health with what we've learned about: Dental health Sleep Heart health Overall wellness The larger idea is that different parts of the body can provide data about the health of the entire system. Genomics and Oculomics Genomics looks at information contained in our genes. Oculomics looks at information contained in the eye. Both represent a broader movement toward using biological data to better understand individual health. Jetstream Fund — Opening Early-Stage Investing Chris also discussed the Jetstream Fund, which is designed to give investors access to early-stage technology investing with smaller investment amounts. Traditional venture capital funds generally have: General Partners (GPs) who manage the fund and Limited Partners (LPs) who provide capital. The Jetstream approach allows investors to participate with smaller checks, potentially around $5,000–$25,000, rather than requiring the much larger commitments often associated with traditional venture capital. The concept is to bring more investors into the early-stage technology ecosystem. The broader investment thesis involves finding technology that has already demonstrated meaningful development and helping companies commercialize that technology.     Tech Topic: https://brt-show.libsyn.com/category/Tech-Startup-VC-Cybersecurity-Energy-Science  Best of Tech: https://brt-show.libsyn.com/size/5/?search=best+of+tech   'Best Of' Topic: https://brt-show.libsyn.com/category/Best+of+BRT      Thanks for Listening. Please Subscribe to the AZ TRT Podcast.     AZ Tech Roundtable 2.0 with Matt Battaglia The show where Entrepreneurs, Top Executives, Founders, and Investors come to share insights about the future of business.  AZ TRT 2.0 looks at the new trends in business, & how classic industries are evolving.  Common Topics Discussed: Startups, Founders, Funds & Venture Capital, Business, Entrepreneurship, Biotech, Blockchain / Crypto, Executive Comp, Investing, Stocks, Real Estate + Alternative Investments, and more…    AZ TRT Podcast Home Page: http://aztrtshow.com/ 'Best Of' AZ TRT Podcast: Click Here Podcast on Google: Click Here Podcast on Spotify: Click Here                    More Info: https://www.economicknight.com/azpodcast/ KFNX Info: https://1100kfnx.com/weekend-featured-shows/  

Drug overdoses move fast. The CDC wants communities to get from overdose data to action more quickly. A new overdose prevention data channel brings several federal data sources together in one place to help track local trends. Federal news network's Eric White spoke with Alana Vivolo Cantor of the Centers for Disease Control and Prevention to get more details.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Anabolic androgenic steroids (AAS) are synthetic versions of testosterone, and like naturally produced testosterone, they can increase male sex characteristics and help build muscle. They are prescribed for low testosterone, delayed puberty and muscle loss from severe illness, among other things. But AAS are also used regularly – particularly among gay, bisexual and queer men – without a prescription to gain muscle and improve physical appearance. The health impact of use varies from injection-site infection to sexual dysfunction and high blood pressure, and many people who use AAS have developed creative ways to mitigate risk. Today's episode will introduce AAS as performance enhancing drugs and provide harm reduction strategies that clinicians can employ to mitigate risks associated with their use. Related content:  Kutscher E, Arshed A, Greene RE, Kladney M. Exploring Anabolic Androgenic Steroid Use Among Cisgender Gay, Bisexual, and Queer Men. JAMA Netw Open. 2024 May 1;7(5):e2411088. doi: 10.1001/jamanetworkopen.2024.11088. Kutscher E, Arshed A, Greene R, Kladney M. Exploring Anabolic-Androgenic Steroids Use Among Cisgender Gay, Bisexual, and Queer Men. Drug and Alcohol Dependence. 2025 Feb 1;267:112112. Kutscher E, Arshed A, Greene RE, Kladney M. Harm Reduction Techniques among Cisgender Gay, Bisexual, and Queer Men Using Anabolic Androgenic Steroids: A Qualitative Study. Harm Reduction Journal. 2024;21:196. doi.org/10.1186/s12954-024-01121-8. Kutscher E, Silverman E, Bachi K. Anabolic Androgenic Steroids: Emerging Use Disorder, Mechanisms of Action, and Clinical Considerations for Pharmacotherapy. Focus (Am Psychiatr Publ). 2026 Spring;24(2):168-178. doi: 10.1176/appi.focus.20250045. Clinical decision tool for providers and patients: https://aas-87py.onrender.com/#/providers/ CEI Line: 1-866-637-2342 https://ceitraining.org/

Van mensen met de ziekte van Alzheimer is bekend dat ze tot ver in hun ziekteproces - als ze hun geliefde al kwijt zijn - hun favoriete muziek nog kunnen herkennen. Hoe zit dat met Parkinson? Speelt muziek daar ook een positieve rol? Onderzoeker Bas Bloem vermoedt van wel. Hij gaat onderzoeken of kunst dezelfde ziekte-remmende werking heeft als sporten. En verder: de sterrencast achter de schermen bij De Staat.

The obesity drug market is shifting from scarcity to fierce competition, as new pills, direct-to-consumer pricing and looming patent expirations upend what was once a two-player race. With one in five U.S. households now including a GLP-1 user, we will break down what the next phase means for healthcare investors and for the food, apparel and employer health costs these drugs are already reshaping.Also in this podcast: EME - Emcor group Inc., MDT - Medtronic PLC, GLW - Corning Inc., CROX - Crocs Inc., LULU - Lululemon Athletica Inc., BAH - Booz Allen Hamilton Holding Corp; also, a question about XRP, plus Luke's MARKET WRAP UP, and his topic talking points: "Freight Costs" and “Household financial Health”. Our Sponsors:* Check out Anthropic and use my code claud.ai/invest for a great deal: https://www.anthropic.com* Check out Quince and use my code quince.com/INVEST for a great deal: https://www.quince.com* Check out Scribe and use my code scribe.how/invest for a great deal: https://scribe.comAdvertising Inquiries: https://redcircle.com/brands

He walked into church wearing last night's club outfit, sunglasses still on, clip-on earrings still clipped and he promptly fell asleep and started snoring. Then a couple sitting behind him did something he never forgot: they steadied him with a gentle hand, prayed for him, and told him, “You belong here.” That single moment of kindness became a turning point in a much longer story of grief, honesty, and a hard-earned return to faith.Nancy sits down with Chris Jang for the full extended conversation of episode #127, tracing his journey from a childhood surrounded by belief to years of pushing away from church through partying, fraternities, bartending, and eventually running illegal after-hours events where drugs and cash were part of the business model. When Chris' brother Andrew dies from a heroin overdose, the shock forces Chris to face what his life has become and what it's costing his family. What follows isn't a neat, instant conversion story, but a slow, intellectual pursuit of Jesus through Christian apologetics, books like The Case for Christ, and a growing conviction that belief has to become obedience.If you care about Christian testimony, redemption stories, grief and recovery, or the power of community to change a life, you'll find yourself thinking about this conversation long after it ends. Subscribe, share with a friend, and leave a review so more people can find Ordinary People Extraordinary Things.https://generationstogenerations.com/podcastordinarypeoplestories@gmail.comhttps://www.facebook.com/ordinarypeoplestoryhttps://www.instagram.com/ordinarypeopleextraordinary/X: @storiesextra Any advice should be confirmed with a qualified professional.All rights reserved: Ordinary People Extraordinary ThingsStories shared by guests may not always be shared views  of OPET. Being a guest does not mean OPET approves of every decision or action in the guests' life. We all have a story, all of us, share your story. You don't have to have the perfect answer or the perfect life - share what Jesus is doing in your life. This is an easy, real way to witness & share your testimony.

Finding a drug that works is only half of the challenge. Understanding WHY it works can open up paths to entire families of drugs that treat a myriad of diseases. Aarati tells the story of the Nobel Prize winning scientist who defied all expectations and created treatments for cancer, organ transplants, viral infections and more.Support the showFor more information and sources for this episode, visit https://www.smartteapodcast.com. 

ACLED's September 17 analysis shows Sinaloa's Chapitos–Mayos war didn't end in year two—it relocated. Overall organized-crime violence dropped about 28% as Los Mayos gained ground around Culiacán, while Mazatlán and Escuinapa absorbed the fight, drones filled the gap left by fewer street clashes, and the blood spilled into Baja California and Zacatecas. This is what a cartel civil war looks like when the map changes but the war doesn't quit.

Author Christopher Armitage joins Thom - is there anything actually conservative about Trump "conservatives"? Plus - are Donald's attempts to restrict media reporting on himself and his scams fundamentally unAmerican?See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

You might think Alzheimer's starts in your 70s. Dr. David Perlmutter explains why it begins decades earlier, and how the p-tau 217 blood test flags risk long before symptoms appear. Gary Brecka and Dr. Perlmutter break down microglia, insulin resistance, pre-diabetes, APOE4, homocysteine, vitamin D, creatine and sleep, plus what the POINTER study showed about cognitive decline in metabolically compromised adults. CLICK HERE TO BECOME GARY'S VIP!: https://bit.ly/4ai0Xwg Get Dr. David Perlmutter's book, “Brain Defenders”: https://bit.ly/4xvoYtY Listen to Dr. David Perlmutter on all your favorite platforms! YouTube: https://bit.ly/46rZjan  Spotify: https://bit.ly/4dxPdZl  Apple Podcasts: https://bit.ly/4dBz19u  Connect with Dr. David Perlmutter Website: https://bit.ly/4yEhBBk  YouTube: https://bit.ly/46rZjan  Instagram: https://bit.ly/3VgElZH  Facebook: https://bit.ly/4xvTC6v  TikTok: https://bit.ly/4xXDcEM  X: https://bit.ly/4xxJdal  LinkedIn: https://bit.ly/4yfpNIF  Thank you to our partners A-GAME: “ULTIMATE15” FOR 15% OFF: http://bit.ly/4kek1ij AION: “ULTIMATE10” FOR 10% OFF: https://bit.ly/4h6KHAD AIRES: “ULTIMATE20” FOR 20% OFF: https://bit.ly/4a3Duze BAJA GOLD: “ULTIMATE10” FOR 10% OFF: https://bit.ly/3WSBqUa BODYHEALTH: “ULTIMATE20” FOR 20% OFF: http://bit.ly/4e5IjsV COLD LIFE: THE ULTIMATE HUMAN PLUNGE: https://bit.ly/4eULUKp CYMBIOTIKA: “BRECKACYM30” FOR 30% OFF: https://bit.ly/4tjyluP GENETIC METHYLATION TEST (UK ONLY): https://bit.ly/48QJJrk GENETIC TEST (USA ONLY): https://bit.ly/3Yg1Uk9 GOPUFF: GET YOUR FAVORITE SNACK!: https://bit.ly/4obIFDC H2TABS: “ULTIMATE10” FOR 10% OFF: https://bit.ly/4hMNdgg HEALF: 10% OFF YOUR ORDER: https://bit.ly/41HJg6S PEPTUAL: “TUH10” FOR 10% OFF: https://bit.ly/4mKxgcn SNOOZE: LET'S GET TO SLEEP!: https://bit.ly/4pt1T6V WHOOP: JOIN & GET 1 FREE MONTH!: https://bit.ly/3VQ0nzW Watch the “Ultimate Human Podcast” every Tuesday & Thursday at 9AM EST: YouTube: https://bit.ly/3RPQYX8 Podcasts: https://bit.ly/3RQftU0 Connect with Gary Brecka Instagram: https://bit.ly/3RPpnFs TikTok: https://bit.ly/4coJ8fo X: https://bit.ly/3Opc8tf Facebook: https://bit.ly/464VA1H LinkedIn: https://bit.ly/4hH7Ri2 Website: https://bit.ly/4eLDbdU Merch: https://bit.ly/4aBpOM1 Newsletter: https://bit.ly/47ejrws Ask Gary: https://bit.ly/3PEAJuG Timestamps 00:00 - Intro of the Show 01:33 - Grain Brain and ultra-processed carbohydrates 03:26 - Pre-diabetes decades before any symptoms 08:03 - Type 3 diabetes and insulin in the brain 11:48 - The fasting insulin level to target 14:08 - Immunometabolism and your microglial cells 16:12 - APOE4 as predisposition, not destiny 19:25 - Inflammation from the gut, mouth and air 25:50 - Aerobic vs resistance training for the brain 30:04 - Sarcopenia, myokines and BDNF 34:44 - Mitochondria and the TSPO brain scan 40:11 - The Tanzi, Ornish and POINTER trials 46:31 - Beta-amyloid drugs and the Cochrane data 55:00 - Sleep, the glymphatic system and insulin 58:25 - Creatine dosing and the creatinine confusion 1:03:52 - Vitamin D, VDR polymorphisms and tau 1:09:35 - Fish oil, DHA and the omega-3 study 1:12:48 - Homocysteine, B complex and MTHFR 1:18:43 - Red light, RNS60 and mitochondrial transplant 1:27:11 - Isolation, cortisol and oxytocin 1:32:58 - What it means to be an ultimate human Disclaimer: This podcast is for informational purposes only and does not provide medical advice. It is not intended for diagnosing or treating any health condition. Always consult a licensed healthcare professional before making health or wellness decisions. Gary Brecka is the owner of Ultimate Human, LLC which operates The Ultimate Human podcast and promotes certain third-party products used by Gary Brecka in his personal health and wellness protocols and daily life and for which Ultimate Human LLC and / or Gary Brecka directly or indirectly holds an economic interest or receives compensation.  Accordingly, statements made by Gary Brecka and others (including on The Ultimate Human podcast) may be considered promotional in nature. Learn more about your ad choices. Visit megaphone.fm/adchoices

(September 22, 2026) ABC News Technology Reporter Mike Dobuski talks to Bill about META Connect. Drug cartels are making alarming drone advances, U.S. assessment warns. Buying a first home isn't completely impossible - you just have to learn to settle. Why caring for grandchildren may help slow cognitive decline.See omnystudio.com/listener for privacy information.

Daraxonrasib is giving new hope to cancer specialists and patients.

On this episode, I spoke with Jonathan Kimmelman, PhD, professor of biomedical ethics and associate member of the Department of Experimental Medicine at McGill University, about the ethical concerns surrounding Kalshi as it relates to clinical trial outcomes and FDA approvals.

Mexico is sending roughly 3,400 more troops from the Army, Navy, and SSPC into Sinaloa, with Mazatlán, Culiacán, and the state's highways as priorities. The reinforcements arrive in the middle of a Chapitos-Mayos war now more than two years old. SEDENA has pointed to large 2026 statewide seizure and lab totals as evidence of progress. But past surges suggest force can quiet the headlines without resolving the fight over territory and routes.

Staying ahead of organised drug gangs is the daily challenge facing the scientists and analysts at Forensic Science Ireland (FSI).And with criminal organisations having their own sophisticated labs to make new drugs, genetically engineer existing ones and disguise drugs in all manner of inventive ways to avoid customs detection, it requires considerable expertise.“Camouflaged cocaine” blended with coal or soaked in plywood are increasingly common.In labs across FSI's new 13,000sqm base near Celbridge, Co Kildare scientists analyse fingerprints, bodily fluids, chemicals and exhibits, including murder weapons and victims' clothing. It is their evidence that is used in court.Irish Times security and crime editor Conor Lally speaks to the In The News podcast about his wide-ranging interview with FSI boss Ciarán Seoighe.Presented by Bernice Harrison. Produced by Andrew McNair. Hosted on Acast. See acast.com/privacy for more information.

Greenland. Drug prices. H-1B. Hunters and anglers.President Trump had a consequential week — but what actually changed, what's still pending, and what should Americans be watching next?Doug Billings breaks down the facts, the policy, and the unanswered questions in this edition of The Right Side.Facts. Context. Results.Believe it. For the Republic! Cheers. #DonaldTrump #Trump #Greenland #DrugPrices #H1B #Hunters #AmericaFirst #TheRightSide #DougBillings  Support the show

Taylor Frankie Paul is at-risk of losing custody of her kids altogether as new court documents reveal she failed multiple drug tests recently. Plus, Patrick Clancy is joined by wife Rachel in his new 60 Minutes interview. Ed Sheeran's beef with Macklemore continues to escalate and Chelsea Handler gets dragged into the mess! And Shailene Woodley's stylist responds to the Emmys hate. For a limited time, save 20% on your first subscription order of AG1 Next Gen or AG1 Pro at https://drinkag1.com/NOFILTER Find your next fall favorites at Quince. Download the Quince app for app-exclusive offers, or go to https://www.quince.com/nofilter Hero Bread is offering 10% off your order. Go to https://www.hero.co/ and use code NOFILTER at checkout.Get the smile of your dreams with SmileSet! Save 35% when you go to https://smileset.com/nofilter See if you could save when you switch to Progressive. You'll feel good about making a savvy choice. Visit https://www.progressive.com/ and see if you can enjoy a little extra cash back.Become a Member of No Filter: ALL ACCESS: https://allaccess.supercast.com/ Shop New Merch now: https://merchlabs.com/collections/zack-peter?srsltid=AfmBOoqqnV3kfsOYPubFFxCQdpCuGjVgssGIXZRXHcLPH9t4GjiKoaio Watch Disaster Daters: https://open.spotify.com/show/3L4GLnKwz9Uy5dT8Ey1VPiBook a personalized message on Cameo: https://v.cameo.com/e/QxWQhpd1TIbDisclaimer: The views expressed in this video, on this YouTube Channel, and on No Filter with Zack Peter are for entertainment purposes only. All content is protected under Fair Use Rights.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

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You say "steroids" and picture a baseball scandal, a jacked guy, a bad spray tan. But cortisol is a steroid. Estrogen is a steroid. The cream you put on poison ivy is a steroid. The word covering all of them is also covering testosterone therapy for women, and that collision is quietly costing women muscle and bone they don't have to lose.In this solo episode, prompted by a magazine interview on steroid use in women, Dr. Gabrielle Lyon breaks down what these molecules actually are, what they do inside a cell, and why the line between medicine and misuse has nothing to do with the word "steroid."Study and References:The Effects of Supraphysiologic Doses of Testosterone on Muscle Size and Strength in Normal Men (Bhasin et al., NEJM 1996) - https://pubmed.ncbi.nlm.nih.gov/8637535/Testosterone Enhances Estradiol's Effects on Postmenopausal Bone Density and Sexuality (Davis et al., 1995) - https://pubmed.ncbi.nlm.nih.gov/7616872/Global Consensus Position Statement on the Use of Testosterone Therapy for Women (2019) - https://pubmed.ncbi.nlm.nih.gov/31498...ISSWSH Clinical Practice Guideline for the Use of Systemic Testosterone for HSDD in Women (2021) - https://pubmed.ncbi.nlm.nih.gov/33814...The Global Epidemiology of Anabolic-Androgenic Steroid Use: A Meta-Analysis (Sagoe et al., 2014) - https://pubmed.ncbi.nlm.nih.gov/24582...What Is the Prevalence of Anabolic-Androgenic Steroid Use Among Women? A Systematic Review (Piatkowski et al., Addiction, 2024) - https://onlinelibrary.wiley.com/doi/1... "The Compounds for Females Are Really Commonly Faked!": Women's Challenges in Anabolic Steroid Acquisition (Piatkowski et al., Drug and Alcohol Review, 2024) - https://onlinelibrary.wiley.com/doi/1... Explore More from Dr. Gabrielle Lyon:Premium Podcast Subscription: Ad-free episodes, key takeaway summaries, exclusive Q&A, and behind-the-scenes content https://foreverstrong.supercast.comWeekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon's clinical team https://drgabriellelyon.com/new-patie...

Lewis Rice spent 26 years inside the DEA, working undercover cases and helping take down some of the biggest drug traffickers in America in the 1970's, 80's & 90's. After earning his Criminal Justice degree from St. John's University, he joined the DEA and went on to coordinate major international investigations targeting violent cartels in Miami — cases that seized millions of dollars in cash and thousands of kilos of cocaine and heroin. He worked directly with infamous Harlem drug kingpin Frank Lucas after Lucas became a government cooperator, using his information to help convict major traffickers. Rice eventually rose through DEA leadership positions in Washington, D.C., Philadelphia, Detroit, and New York before becoming Special Agent in Charge of the DEA's flagship New York office — making him the youngest SAC in the entire agency at the time. After 26 years on the front lines of America's war on drugs, he retired in 2001. _____________________________________________  #miami #truecrimestories #cops #mafia #newyork _____________________________________________ Thank you to CASH APP for sponsoring this episode: Download Cash App Today: https://click.cash.app/ui6m/6pao71et #CashAppPod Cash App is a financial services platform, not a bank. Banking services provided by Cash App's bank partner(s). Prepaid debit cards issued by Sutton Bank, Member FDIC. Cash App Visa® Debit Flex Cards issued by Sutton Bank, Member FDIC, and The Bancorp Bank, N.A., pursuant to a license from Visa U.S.A. Inc. See terms and conditions for the Sutton prepaid card, Sutton debit flex card, and Bancorp debit flex card. Discounts and promotions provided by Cash App, a Block, Inc. brand. Visit cash.app/legal/podcast for full disclosures. _____________________________________________ Buy Lewis's Book: https://www.amazon.com/dp/0805978712?lv=shuf&channelId=500&plpRedirect=mhFallback _____________________________________________ Hosted, Executive Produced & Edited By Ian Bick: https://www.instagram.com/ian_bick/?hl=en https://ianbick.com/ _____________________________________________ Timestamps: 00:00 Frank Lucas Cooperates 00:32 Lewis Rice's Career and the DEA's Early Days 01:01 The Birth of the DEA in the 1970s 03:30 Growing Up in New York City 04:42 Friends' Heroin Addiction Inspires Mission 06:09 Influence of His Father 07:08 Family Background and Internships 08:51 Rikers Island Intern Experience 11:12 Starting at the DEA at 21 12:56 DEA's Size and Focus 13:12 Academy and Early Training 14:50 Legendary Supervisor Frank White 15:33 Typical Recruits in the Early DEA 16:37 Acceptance as a Young Agent 18:10 The Importance of Undercover Work 19:21 First Undercover Cases 21:21 Negotiating Drug Deals 22:00 Showing Money and Dealer Psychology 23:11 The Informant's Role 25:03 How Informants Were Found 26:36 Arresting Dealers and Building Cases 27:47 Dealers' Knowledge of the DEA 28:41 An 8-Month Undercover Investigation 29:47 Going to Trial in the 70s 30:40 Defendants Released by Magistrate 31:14 The 'Champion' Fugitive 33:03 DEA's Most Wanted and Frank Matthews 36:21 Conviction Success Rates 37:41 Working a Case with the US Attorney 38:54 Handwritten Reports and Courtroom Drama 39:42 Prosecutors' Advice on Evidence 40:49 Sentences in the 70s 41:24 High-Level Enforcement in Philadelphia 42:44 Community Impact of Mass Arrests 44:06 Drug Dealers in Their Communities 45:02 Hardcore Dealers Like Herby Sperling 45:49 Modern Dealers Cut Deals 46:03 Talking to Kids About Drug Crimes 49:01 Mafia's Role in 70s Heroin Supply 51:02 The French Connection and Source Countries 53:26 Mafia Families and Drug Politics 54:26 Money Laundering in the 70s 55:50 Cash Seizures and Stash Houses 57:44 Counting Money in Miami Cases 01:00:10 Seeing Large Amounts of Cash 01:01:35 Case Without Drugs or Money 01:02:00 The American Gangster Case 01:02:57 The Manite and Quinine Investigation 01:04:36 Prosecuting with Circumstantial Evidence 01:06:24 Bringing Frank Lucas to Testify 01:08:00 Controversy Over Frank's Cooperation 01:09:05 The Importance of Truthful Testimony 01:09:57 Was Frank's Deal Worth It? 01:11:19 Frank Lucas's Charm and Success 01:13:30 Cooperating as a Business Decision 01:14:17 Frank's Witness Protection 01:15:16 Frank's Testimony Convicts Gang 01:16:39 Frank Lucas Calls Years Later 01:17:33 Sentencing Reduction for Frank 01:19:38 Frank's Murder Trial and Acquittal 01:21:07 Moving to Jamaica 01:21:47 Life in Jamaica as a Black American 01:24:15 Objective in Jamaica: Marijuana Smuggling 01:25:05 Cultural Experiences in Jamaica 01:27:16 US Embassy's Power and Opportunities 01:29:31 Extraditing Drug Traffickers 01:30:43 Liaison Work with Two Agents 01:32:39 Two Years in Jamaica, Then Miami 01:33:18 Supervising in Miami in the Cocaine Era 01:35:10 Undercover as a Supervisor 01:37:00 Violence and Dadeland Shootout 01:39:03 Two-Year Assignments and FBI Influence 01:41:11 Relationship with Local Cops 01:42:22 Personal Life and Career Demands 01:44:04 Returning to New York 01:45:30 Changes in the Drug Game 01:46:30 Evolution of Drugs: From Heroin to Fentanyl 01:49:01 Overdoses in the 90s 01:50:26 Running the New York Task Force 01:52:30 Improving Morale After Corruption Scandal 01:54:40 Impact of Truth-in-Sentencing 01:56:29 Moving Up in the DEA 01:58:53 Becoming Special Agent in Charge 01:59:58 Role as Special Agent in Charge 02:00:53 Politics and Law Enforcement 02:02:00 NYPD Ownership of the City 02:04:59 Toughest Challenge as SAC 02:09:40 Supervisor's Responsibility for Safety 02:12:52 Length of Tenure as SAC 02:13:45 Retiring from the DEA 02:14:54 Retirement Emotions 02:15:45 Missing the Brotherhood 02:16:39 Perspective 25 Years Post-Retirement 02:18:38 Reconnecting with the DEA and Chelsea Market 02:20:20 Technology vs. Human Relationships 02:21:10 Leadership and Morale 02:23:18 Fixing the Drug Problem 02:24:21 Advice to a 21-Year-Old 02:27:32 Closing Thoughts _____________________________________________ To advertise on the show, contact sales@advertisecast.com or visit https://advertising.libsyn.com/LockedInWithIanBicka

The Lindsay Clancy case is one of the most gut-wrenching tragedies making headlines, and has torn the public opinion, (and even relationships) apart. Was it unspeakable heartbreak? Psychosis? Or criminal intent, plain and simple? Today, I'm joined by forensic psychologist Dr. Shannon Curry, the woman who bravely took the stand in the Depp-Heard trial, to unravel the real-life consequences every woman needs to think about. Not just for herself, but for every mother, wife, and daughter who might need help before it's too late.We break down the psychology, the law, and those impossible “what would I do?” dilemmas that are dividing men, women, and the world.Here's exactly what we dive into:The difference between baby blues, postpartum depression, and postpartum psychosis (and why most mothers never, ever hurt their children)The systems failures that are failing mothers, and what HAS to changeWhy women often hide dark thoughts, and why “blaming the husband” misses the real pointThe crucial first step to get help, without fear, shame, or losing your kidsChapter Titles:Baby Blues vs. Postpartum Depression vs. Psychosis: The Real RisksThe Truth About Postpartum Psychosis and Filicide: Numbers No One Tells YouMeds, Misdiagnosis & System Failure: Is This the Real Root?Overmedication, Missed Warnings & Hindsight BiasShould Kids Be Taken Away? The Danger of OverreactionIntrusive Thoughts vs. Hallucinations: How to Tell the DifferenceDid the Medical System Fail Her? Ethics, Testing, and Protocol DebatesWhy This Case Divides Men and Women, and the Hidden Biases at PlayCan Insanity “Set You Free”? What Actually Happens If You're AcquittedIf You're Struggling Right Now: What to Do and How to Get Help“I Don't Feel Understood”: How Partners Can Actually Hear Each OtherThank you To our Sponsors:Shopify: Sign up for a free trial at https://shopify.com/lisaQualia: Go to qualialife.com/LISA and use code LISA for 15% offNeed Support? These Resources Can Help: 988 Suicide & Crisis Lifeline: https://988lifeline.org/ The National Maternal Mental Health 24/7 Hotline: https://mchb.hrsa.gov/programs-impact/national-maternal-mental-health-hotline?gad_source=1&gad_campaignid=24031728478 National Helpline for Mental Health, Drug, Alcohol Issues | SAMHSA: https://www.samhsa.gov/find-help/helplines/national-helpline Follow Shannon Curry:Website: https://currypsychology.com/ Instagram: https://www.instagram.com/currypsychgroupFollow Me, Lisa Bilyeu:Website: https://www.lisabilyeu.comInstagram: https://www.instagram.com/lisabilyeu/Facebook: https://www.facebook.com/lisabilyeuSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

The tragic case of Lindsay Clancy has ignited a national conversation about postpartum psychosis, maternal mental health, and criminal responsibility. Clinical psychologist Dr. Roger McFillin of The Radically Genuine Podcast believes a critical part of the story has been largely overlooked: the psychiatric care Lindsay received in the months leading up to what happened.Roger returns to Down to Birth to examine Lindsay's medical history, severe sleep deprivation, reported reactions to psychiatric drugs, and the extraordinary number of prescriptions she received from multiple providers in a matter of months. We discuss what happens when adverse drug reactions are interpreted as worsening mental illness, why the psychiatric standard of care deserves greater scrutiny, and whether what happened to Lindsay was truly postpartum psychosis at all.We also confront the difficult question of personal responsibility, and whether the role of psychiatric drugs and medical care can be examined separately from the question of criminal responsibility. Although this is a deeply unsettling topic, we feel families will benefit from the facts of this case, particularly around informed consent, the known side effects of psychiatric drugs, personal accountability, and a medical system Roger believes failed Lindsay Clancy and her family long before she committed this unimaginable tragedy. We hope this conversation offers reassurance to mothers who have been left fearing that postpartum psychosis can simply strike without warning, while encouraging women to trust themselves, ask questions, and understand the risks and benefits of the care they receive. We also hope it helps fathers to better understand what to watch for, what questions to ask, and how to advocate for and protect the women and children they love.**********Check out our previous episode with Dr. Roger McFillin here:#235 | Solution or Sham? The Anti-Depressant Industry Exposed with Dr. Roger McFillinAccess our workshops on postpartum:Understanding Postpartum PsychosisOvercoming Postnatal DepletionPostpartum Rage: What To Do About ItSend us Fan Mail Support the showAccess our workshops: Have a Physiologic Birth in the Hospital and Ultrasound: The Research vs RhetoricNeeded

In 2023, Marlena Arjo adopted a one-eyed kitten with a penchant for destruction. She named him Otto, and over the next eight months, Otto grew into his own little chaotic personality.“ He's laying on houseplants, he's tearing books out of the bookshelves, ripping the calendar off the wall…I wasn't prepared for having a criminal in my home,” Arjo joked.Within months, Otto got sick and stopped eating. Arjo rushed him to a vet and learned he had feline infectious peritonitis, better known as FIP, a disease that kills nearly all cats that contract it. The vet said there was nothing the clinic could do. But there was something Arjo could do.“I shouldn't tell you this,” Arjo recalled the vet telling her. “But by the way, you can get drugs for this if you go to this Facebook group.”This week on Reveal, in partnership with the Hyperfixed podcast, we tell the story of the cat drug black market, why it was even necessary, and how cat lovers fought for big changes to make the black market obsolete.This is an update of a show that originally aired in January 2026.Listen to Hyperfixed's greatest hits Support Reveal's journalism at Revealnews.org/donatenow Subscribe to our weekly newsletter to get the scoop on new episodes at Revealnews.org/weekly Connect with us onBluesky, Facebook and Instagram Learn about your ad choices: dovetail.prx.org/ad-choices