Podcasts about stanford medicine

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Best podcasts about stanford medicine

Latest podcast episodes about stanford medicine

KCBS Radio In Depth
Biden's diagnosis, explained by a cancer doctor

KCBS Radio In Depth

Play Episode Listen Later May 18, 2025 3:54


Former President Joe Biden has been diagnosed with an aggressive form prostate cancer. To break down the diagnosis, KCBS Radio anchor Alisa Clancy spoke with Dr. Sandy Srinvas, Professor of Oncology specializing in urology at Stanford Medicine.

From Our Neurons to Yours
Building AI simulations of the human brain | Dan Yamins

From Our Neurons to Yours

Play Episode Listen Later May 1, 2025 32:56 Transcription Available


This week on the show: Are we ready to create digital models of the human brain? Last month, Stanford researcher Andreas Tolias and colleagues created a "digital twin" of the mouse visual cortex. The researchers used the same foundation model approach that powers ChatGPT, but instead of training the model on text, the team trained in on brain activity recorded while mice watched action movies. The result? A digital model that can predict how neurons would respond to entirely new visual inputs. This landmark study is a preview of the unprecedented research possibilities made possible by foundation models of the brain—models which replicate the fundamental algorithms of brain activity, but can be studied with complete control and replicated across hundreds of laboratories.But it raises a profound question: Are we ready to create digital models of the human brain? This week we talk with Wu Tsai Neuro Faculty Scholar Dan Yamins, who has been exploring just this question with a broad range of Stanford colleagues and collaborators. We talk about what such human brain simulations might look like, how they would work, and what they might teach us about the fundamental algorithms of perception and cognition.Learn moreAI models of the brain could serve as 'digital twins' in research (Stanford Medicine, 2025)An Advance in Brain Research That Was Once Considered Impossible (New York Times, 2025)The co-evolution of neuroscience and AI (Wu Tsai Neuro, 2024)Neuroscientists use AI to simulate how the brain makes sense of the visual world (Wu Tsai Neuro, 2024)How Artificial Neural Networks Help Us Understand Neural Networks in the Human Brain (Stanford Institute for Human-Centered AI (HAI), 2021)Related researchA Task-Optimized Neural Network Replicates Human Auditory Behavior... (PNAS, 2014)Vector-based navigation using grid-like representations in artificial agents (Nature, 2018)The neural architecture of language: Integrative modeling converges on predictive processing (PNAS, 2021)Using deep reinforcement learning to reveal how the brain encodes abstract state-space representations... (Neuron, 2021) We want to hear from your neurons! Email us at at neuronspodcast@stanford.edu. Send us a text!Thanks for listening! If you're enjoying our show, please take a moment to give us a review on your podcast app of choice and share this episode with your friends. That's how we grow as a show and bring the stories of the frontiers of neuroscience to a wider audience. Learn more about the Wu Tsai Neurosciences Institute at Stanford and follow us on Twitter, Facebook, and LinkedIn.

From Our Neurons to Yours
What ChatGPT understands: Large language models and the neuroscience of meaning | Laura Gwilliams

From Our Neurons to Yours

Play Episode Listen Later Apr 17, 2025 42:31 Transcription Available


If you spend any time chatting with a modern AI chatbot, you've probably been amazed at just how human it sounds, how much it feels like you're talking to a real person. Much ink has been spilled explaining how these systems are not actually conversing, not actually understanding — they're statistical algorithms trained to predict the next likely word. But today on the show, let's flip our perspective on this. What if instead of thinking about how these algorithms are not like the human brain, we talked about how similar they are? What if we could use these large language models to help us understand how our own brains process language to extract meaning? There's no one better positioned to take us through this than returning guest Laura Gwilliams, a faculty scholar at the Wu Tsai Neurosciences Institute and Stanford Data Science Institute, and a member of the department of psychology here at Stanford.Learn more:Gwilliams' Laboratory of Speech NeuroscienceFireside chat on AI and Neuroscience at Wu Tsai Neuro's 2024 Symposium (video)The co-evolution of neuroscience and AI (Wu Tsai Neuro, 2024)How we understand each other (From Our Neurons to Yours, 2023)Q&A: On the frontiers of speech science (Wu Tsai Neuro, 2023)Computational Architecture of Speech Comprehension in the Human Brain (Annual Review of Linguistics, 2025)Hierarchical dynamic coding coordinates speech comprehension in the human brain (PMC Preprint, 2025)Behind the Scenes segment:By re-creating neural pathway in dish, Sergiu Pasca's research may speed pain treatment (Stanford Medicine, 2025)Bridging nature and nurture: The brain's flexible foundation from birth (Wu Tsai Neuro, 2025)Get in touchWe want to hear from your neurons! Email us at at neuronspodcast@stanford.edu if you'd be willing to help out with some listener research, and we'll be in touch with some follow-up questions.Episode CreditsThis episode was produced by Michael Osborne at 14th Street Studios, with sound design by Morgan Honaker. Our logo is by Aimee Garza. The show is hosted by Nicholas Weiler at Stanford's Send us a text!Thanks for listening! If you're enjoying our show, please take a moment to give us a review on your podcast app of choice and share this episode with your friends. That's how we grow as a show and bring the stories of the frontiers of neuroscience to a wider audience. Learn more about the Wu Tsai Neurosciences Institute at Stanford and follow us on Twitter, Facebook, and LinkedIn.

From Our Neurons to Yours
What the other half of the brain does | Brad Zuchero

From Our Neurons to Yours

Play Episode Listen Later Apr 3, 2025 35:00 Transcription Available


We've talked about glia and sleep. We've talked about glia and neuroinflammation. We've talked about glia in the brain fog that can accompany COVID or chemotherapy. We've talked about the brain's quiet majority of non–neuronal cells in so many different contexts that it felt like it was high time for us to take a step back and look at the bigger picture. After all, glia science was founded here at Stanford in the lab of the late, great Ben Barres.No one is better suited to take us through this history and lead us to the frontiers of the field than today's guest, Brad Zuchero. A former Barres lab postdoc, and now an emerging leader in this field in his own right, Brad gives us an overview of our growing understanding of the various different kinds of glia and their roles in brain function, and shares the  exciting  discoveries emerging from his lab — including growing evidence of a role for myelin in Alzheimers disease.Learn MoreNeuroscientist Ben Barres, who identified crucial roles of glial cells, dies at 63 (Stanford Medicine, 2017)How exciting! Study reveals neurons rely on glial cells to become electrically excitable (Stanford Neurosurgery, 2024)Unlocking the secrets of myelin repair (Wu Tsai Neurosciences Institute, 2024)Q&A: Linking sleep, brain insulation, and neurological disease with postdoc Daniela Rojo (Knight Initiative for Brain Resilience, 2023)From angel to demon: Why some brain cells go ‘bad' (Scope Blog, 2021)Get in touchWe want to hear from your neurons! Email us at at neuronspodcast@stanford.edu if you'd be willing to help out with some listener research, and we'll be in touch with some follow-up questions.Episode CreditsThis episode was produced by Michael Osborne at 14th Street Studios, with production assistance by Morgan Honaker. Our logo is by Aimee Garza. The show is hosted by Nicholas Weiler at Stanford's Wu Tsai Neurosciences Institute and supported in part by the Knight Initiative for Brain Resilience at Wu Tsai Neuro.Send us a text!Thanks for listening! If you're enjoying our show, please take a moment to give us a review on your podcast app of choice and share this episode with your friends. That's how we grow as a show and bring the stories of the frontiers of neuroscience to a wider audience. Learn more about the Wu Tsai Neurosciences Institute at Stanford and follow us on Twitter, Facebook, and LinkedIn.

City Visions
Journalist Kevin Fagan on 'The Lost and the Found' / Dr. Bryant Lin's Lessons on Lung Cancer

City Visions

Play Episode Listen Later Mar 11, 2025 53:23


State of the Bay offers a compassionate look at homelessness with longtime San Francisco Chronicle journalist Kevin Fagan and examines Stanford Medicine's Dr. Bryant Lin's shift from researching lung cancer to confronting his own terminal diagnosis.

The Future of Everything presented by Stanford Engineering

Physician Ash Alizadeh has seen the future of disease diagnosis and monitoring. It is coursing through every patient's veins. Traditionally, biopsies have required invasively gathering tissue – from a lung, a liver, or a fetus. Now it's possible to look for disease without surgery. The DNA is sitting there in the bloodstream, Alizadeh tells host Russ Altman, as they preview the age of liquid biopsies on this episode of Stanford Engineering's The Future of Everything podcast.Have a question for Russ? Send it our way in writing or via voice memo, and it might be featured on an upcoming episode. Please introduce yourself, let us know where you're listening from, and share your quest. You can send questions to thefutureofeverything@stanford.edu.Episode Reference Links:Stanford Profile: Ash A. Alizadeh, MD/PhDConnect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads / Bluesky / MastodonConnect with School of Engineering >>> Twitter/X / Instagram / LinkedIn / FacebookChapters:(00:00:00) IntroductionRuss Altman introduces guest Ash Alizadeh, a faculty member at Stanford University in Oncology and Medicine.(00:03:39) What is a Liquid Biopsy?Accessing tissues non-invasively using bodily fluids.(00:04:31) Detecting Cancer with Liquid BiopsiesHow localized cancers can be detected through blood samples.(00:06:32) The Science Behind Cancer DNA DetectionThe differences between normal and cancer DNA(00:09:51) How Liquid Biopsy Technology WorksThe technologies behind detecting cancer-related DNA differences.(00:12:36) Advances in Liquid BiopsyNew detection approaches using non-mutant molecules and RNA.(00:14:10) RNA as a Real-Time Tumor MarkerHow RNA reveals active tumor processes and drug resistance.(00:15:55) Tracking Cancer ReccurenceUsing tumor-informed panels to monitor cancer recurrence.(00:16:28)  Adapting to Tumor EvolutionWhy core mutations remain detectable despite cancer changes.(00:17:57) Stability of DNA, RNA, and MethylationComparing durability and reliability of different biomarkers.(00:20:49) Listener Question: Early Cancer DetectionDaniel Kim asks about pre-cancer detection and its potential impact.(00:24:44) Liquid Biopsy in ImmunotherapyUsing liquid biopsy to track and improve immune-based treatments.(00:27:35) Monitoring CAR T-Cell TherapyHow liquid biopsy helps assess immune cell expansion.(00:32:02) EPIC-Seq: Inferring RNA from DNAUsing DNA fragmentation to predict gene expression in tumors.(00:34:49) Targeting Tumor Support SystemsTreatment strategies disrupting the tumor microenvironment.(00:35:52) Conclusion Connect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads / Bluesky / MastodonConnect with School of Engineering >>>Twitter/X / Instagram / LinkedIn / Facebook

Progress, Potential, and Possibilities
Dr. Billy W. Loo Jr., MD, PhD - Professor, Stanford Medicine / Co-Founder, TibaRay - Curing Cancer In A Flash

Progress, Potential, and Possibilities

Play Episode Listen Later Feb 20, 2025 66:54


Send us a textDr. Billy W. Loo Jr., MD PhD ( https://med.stanford.edu/profiles/6839 ) is a Professor of Radiation Oncology, a member of the Stanford Cancer Institute, the Molecular Imaging Program at Stanford (MIPS), and of Bio-X Interdisciplinary Biosciences Institute.  He is a physician-scientist Radiation Oncologist and Bioengineer who directs the Thoracic Radiation Oncology Program and is Principal Investigator of the FLASH Sciences Lab at Stanford ( https://med.stanford.edu/loo-lab.html ).Dr. Loo's clinical specialty is precision targeted radiotherapy for lung/thoracic cancers, including stereotactic ablative radiotherapy (SABR). Dr. Loo is a recognized expert in thoracic cancers serving on multiple national committees (including as writing member or vice-chair) that publish clinical guidelines on the treatment of lung cancer and other thoracic malignancies, particularly the National Comprehensive Cancer Network (NCCN).Dr. Loo's clinical research is in clinical trials and implementation of new treatment techniques for lung cancer, and development of new medical imaging methods for measuring organ function and predicting response to cancer treatment. He also has developed novel applications of SABR including treatment of pulmonary emphysema and cardiac arrhythmias.The research focus of the FLASH Sciences Lab at Stanford, directed by Dr. Loo, is the development and study of extremely rapid FLASH therapy to optimize the biological therapeutic index of cancer radiotherapy, and the technological infrastructure for this basic research and its clinical translation. Dr. Loo is co-inventor of a fundamentally new approach to delivering ultra-rapid, ultra-precise cancer therapy, pluridirectional high-energy agile scanning electronic radiotherapy (PHASER), and co-leads a program to develop it into a transformative and clinically practical technology.Dr. Loo is also a co-founder of an early stage company, TibaRay ( https://www.tibaray.com/ ) developing next generation linear accelerator technology (derived from Stanford research) to bring these advances to patients.Dr. Loo received his MD from University of California, Davis and his PhD in Bioengineering from University of California, San Francisco and Berkeley. He completed his Radiation Oncology residency training at Stanford Medicine. He is certified by the American Board of Radiology in Radiation Oncology, and is a Fellow of the American Society for Radiation Oncology (ASTRO) and a Fellow of the American College of Radiology (ACR).#BillyLoo #Oncology #Cancer #RadiationOncology #FlashRadiotherapy #Stanford #Tibaray #Phaser #Bioengineering  #LinearAccelerator #Klystron #ProgressPotentialAndPossibilities #IraPastor #Podcast #Podcaster #Podcasting #ViralPodcast #STEM #Innovation #Science #Technology #ResearchSupport the show

Smart People Podcast
Why AI Could Be the Key to Better, Faster, and Cheaper Healthcare with Dean of Stanford Medicine, Dr. Lloyd Minor

Smart People Podcast

Play Episode Listen Later Feb 11, 2025 53:23


Transforming The Toddler Years - Conscious Moms Raising World & Kindergarten Ready Kids
How to Feel Like Yourself Again After Having Kids with Jenn Krieg

Transforming The Toddler Years - Conscious Moms Raising World & Kindergarten Ready Kids

Play Episode Listen Later Feb 6, 2025 28:23


Feeling like you've lost yourself since having kids? You are not alone. In this episode, Jenn Kreig from Momma Renew joins me to talk about empowering moms after having kids. We talk about healing hormones and getting energy back, so exhausted, overwhelmed moms can get back to feeling like themselves again. Jenn Kreig is a mom of 2, Board Certified Integrative Health Practitioner (Level 2), and Certified in Nutrition Science and Exercise Science from Stanford Medicine. Jenn is launching her signature 1:1 coaching program RENEW YOU. Book a 30 minute coffee chat to see if the program is a good fit here: https://calendly.com/jenn-erjm/renew-you. Be sure to check out her FREE 5 Ways to Feel Like Yourself Again guide mommarenew.myflodesk.com/feelbetter too! Love the intentional language scripts you can use with your toddler? Check out my newest free gift to you:⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠5 Things Your Toddler Needs to Hear You Say Everyday⁠⁠.⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠Watch and listen as your child starts to respond differently to you. February 6, 2025 Episode 218 How to Feel Like Yourself Again After Having Kids with Jenn Krieg About Your Host: Cara Tyrrell, M.Ed is mom to three girls, a Vermont based Early Childhood Educator and the founder of Core4Parenting. She is the passionate mastermind behind the Collaborative Parenting Methodology™, a birth-to-five, soul and science based framework that empowers toddler parents and educators  to turn tantrums into teachable moments. Through keynotes, teacher training, and her top-ranking podcast, Transforming the Toddler Years, she's teaching the 5 Executive Functioning Skills kids need to navigate our ever-changing world. Ready to raise world-ready kids who change the world? Visit⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠www.caratyrrell.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠to begin your Collaborative Parenting journey!

The Future of Everything presented by Stanford Engineering

Nephrologist Manjula Tamura discusses the downsides of kidney dialysis, especially for old or frail patients. Her field has set its sights on offering alternatives, including supportive medical management without dialysis, dialysis in increments, wearable artificial kidneys, and transplanted kidneys from genetically modified pigs – in addition to advances in preventive care that can help humans avoid kidney failure in the first place. Dialysis can extend life, she says, but it is a lifestyle change. The goal is to ensure that every patient's choice aligns with their values and life goals, Tamura tells host Russ Altman in this episode of Stanford Engineering's The Future of Everything podcast.Have a question for Russ? Send it our way in writing or via voice memo, and it might be featured on an upcoming episode. Please introduce yourself, let us know where you're listening from, and share your quest. You can send questions to thefutureofeverything@stanford.edu.Episode Reference Links:Stanford Profile: Manjula Kurella TamuraConnect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads / Bluesky / MastodonConnect with School of Engineering >>> Twitter/X / Instagram / LinkedIn / FacebookChapters:(00:00:00) IntroductionRuss Altman introduces guest, Manjula Tamura, a professor of medicine and nephrology at Stanford University Medical School.(00:02:58) The Kidney's Vital RoleThe kidney's role and why its failure is life-threatening.(00:04:51) Causes of Kidney FailureThe leading causes of kidney failure in developed countries.(00:07:58) Kidney TransplantationThe feasibility, barriers, and supply challenges of kidney transplantation.(00:09:50) The Dialysis ProcessHow hemodialysis and peritoneal dialysis work and patient experiences.(00:14:07) The Evolution of Dialysis TreatmentThe history of dialysis and how Medicare's expansion influenced its use.(00:18:48) Study Design: Emulating Clinical TrialsUsing VA electronic health records to simulate trials on dialysis.(00:25:31) Findings: Survival vs. Time at HomeThe trade-offs between extended survival and reduced time at home.(00:27:02) Quality of Life and DialysisMeasuring quality of life impacts through electronic health records.(00:30:32) The Future of Kidney TreatmentsInnovations like xenotransplantation and wearable artificial kidneys.(00:33:04) Conclusion Connect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads / Bluesky / MastodonConnect with School of Engineering >>>Twitter/X / Instagram / LinkedIn / Facebook

Short Wave
Bone Marrow Cells: Key To Vaccine Longevity?

Short Wave

Play Episode Listen Later Jan 14, 2025 8:48


The COVID-19 mRNA vaccine generates enough of an antibody response to protect against severe disease for six months. But other vaccines offer years-long — even lifelong — immunity, such as the measles or yellow fever vaccines. Is there a way for scientists to tell how long a person's immunity will last? A team at Stanford Medicine might have found a way to do just that — with the help of some of the cells found in our bone marrow. Questions about vaccines or the respiratory season? Email us at shortwave@npr.org — we'd love to hear from you!Learn more about sponsor message choices: podcastchoices.com/adchoicesNPR Privacy Policy

Nutrients
Can Dietary Fiber Rewrite Your Genetic Code to Combat Cancer?

Nutrients

Play Episode Listen Later Jan 13, 2025 8:35 Transcription Available


In this episode of Daily Value, we take a look at how fiber fuels anti-cancer gene activity - emphasizing the role of short-chain fatty acids (SCFAs) produced during fiber fermentation. Drawing on new research PMID: 39789354) published in Nature Metabolism out of Stanford Medicine, we examine how fiber-derived metabolites influence gene activity to reduce cancer risk and promote overall health.Discussion Points:The epigenetic role of SCFAs, such as butyrate and propionate, in activating anti-cancer genes and inhibiting harmful pathways.Insights from recent studies, including findings showing a 10% reduction in colorectal cancer risk for every 10-gram increase in daily fiber intake.Practical strategies to optimize fiber consumption, including food sources and supplementation options tailored for individual needs.https://pubmed.ncbi.nlm.nih.gov/39789354/Support the show

Ozarks at Large
The future of AI and medicine — A Fayetteville icon receives a face-lift

Ozarks at Large

Play Episode Listen Later Jan 13, 2025 54:56


Artificial Intelligence is part of the present and our future, but how can it help provide better medical care? On today's show, we hear about a conference hosted by the Alice Walton School of Medicine and Stanford Medicine at Crystal Bridges to investigate just that. Also, we hear about the decades-long relationship between Jimmy Carter and Bill Clinton. Plus, the Mount Sequoyah cross is getting a tune-up.

Smart Money Circle
This CEO is working on a drug to slow Alzheimer's – Meet Cuong Do, CEO, Bioviepharm - $BIVI

Smart Money Circle

Play Episode Listen Later Dec 16, 2024 20:31


Guest Name: Cuong Do Title: President & CEO Website: https://bioviepharma.com/ Ticker: BIVI Bio: Cuong Do President & Chief Executive Officer​ Cuong Do, MBA, is the President and Chief Executive Officer of BioVie Inc., a clinical-stage company developing innovative drug therapies for the treatment of neurological and neurodegenerative disorders and advanced liver disease. Do is a highly experienced life sciences executive, who has served in various leadership roles at multiple global enterprises and publicly owned companies over the past 35 years. Prior to his appointment with BioVie, Do was President of Samsung Global Strategy Group where he helped to set the strategic direction for the company's diverse business portfolio, including the growth of its biologics businesses. He was previously the Chief Strategy Officer for Merck, a leading US pharmaceutical company on the Fortune 500 list, where he played a key role in defining the company's strategy, including its focus on oncology and creating its leading position with the anti-PD-1 therapy, pembrolizumab (KEYTRUDA®). Do also held leadership roles in the technology space at Lenovo and Tyco Electronics, and was a senior partner at McKinsey & Company, where he spent 17 years helping to build the company's healthcare, high tech and corporate finance practices. Do is an active entrepreneur who founded Callidus Biopharma (a biotech company working in rare diseases that was acquired by Amicus Therapeutics in 2013), Lysodel Therapeutics (a company developing an innovative pharmaceutical product for obesity), and M6P Therapeutics (a company developing gene and enzyme replacement therapies for rare lysosomal storage disorders). He is a founding member of Social Impact Partners, which is a purpose-driven alliance of global experts and young change-makers working to fight against Alzheimer's Disease. Do also serves as a member of multiple advisory boards to companies and academic institutions, including Seneca Therapeutics, Stanford Medicine, The Tuck School of Business at Dartmouth, Fulbright University Vietnam, Ideal Semiconductors, ILiAD Biotechnologies and others. Do is also a passionate philanthropist, particularly in autism and education. He founded Profectum Foundation, which specializes in providing training and education for professionals and parents of children with autism or special needs. He also founded Identifor, Inc. and the Identifor Foundation to help autistic teenagers identify abilities and strengths to make the transition to adulthood. He currently or formerly served on the boards of Celebrate the Children (a school for children with special needs in New Jersey), Autism Speaks and its Executive, Strategy, Science and Family Services committees and Caring for Cambodia (a non-profit working to educate 7,000+ K-12 students in Siem Reap, Cambodia). He holds a BA from Dartmouth College, and an MBA from the Tuck School of Business at Dartmouth. --- Support this podcast: https://podcasters.spotify.com/pod/show/smartmoneycircle/support

Un Mensaje a la Conciencia
«¿Cómo puedo librarme de la adicción a las redes sociales?»

Un Mensaje a la Conciencia

Play Episode Listen Later Dec 12, 2024 4:01


En este mensaje tratamos de manera anónima la siguiente petición que nos hizo un hombre: «Me gustaría recibir información acerca de cómo librarme de la adicción a las redes sociales.» Este es el consejo que le dio mi esposa: «Estimado amigo: »... Por lo general se cree que la mayoría de las personas que usan en exceso las redes sociales no son, en realidad, adictas a ellas.... Así que para efectos de este consejo nos limitaremos a ofrecer información sobre cómo valerse de las redes sociales de una manera sana. »Es importante señalar que la mayoría de esas personas que usan en exceso las redes sociales no pueden simplemente dejar de usarlas, tal como pueden hacer las que abusan de las drogas y del alcohol. Vivimos en una época en la que el uso de la Internet es prácticamente obligatorio.... »Por lo tanto, el dilema consiste en cómo usar la Internet y las redes sociales de diversas maneras que tengan un efecto positivo en nuestra vida sin caer en las trampas diseñadas con el fin de que hagamos lo contrario. Ya muchos saben que las redes sociales se valen de complicadas fórmulas estadísticas llamadas algoritmos a fin de impulsarnos a mantenernos conectados más tiempo. Cuando interactuamos comentando o indicando que nos gusta, ese obvio interés de nuestra parte hace que el algoritmo de la plataforma de la red social nos ofrezca más contenido que es muy similar. »El aceptar y seguir tales ofrecimientos hace que la sustancia química llamada dopamina sea emitida en nuestro cerebro. Y la dopamina hace que tengamos sensaciones de placer que nos impulsan a hacer lo que sea necesario para tener más de esas sensaciones. Con el tiempo, se necesita cada vez más interacción con las redes sociales para liberar la misma cantidad de dopamina, por lo que gradualmente aumentamos el tiempo que pasamos en las redes sociales. »Además, ciertas personas se sienten complacidas consigo mismas cuando lo que publican, incluso sus fotos, generan muchos comentarios y reacciones de “Me gusta”. En otras personas, a la inversa, se desata un dañino ciclo de autocondenación al comparar su propia vida con la vida pública, y frecuentemente alterada, de los demás. Diversos estudios han demostrado que el uso excesivo de las redes sociales contribuye a la baja autoestima, el aislamiento y soledad, la ansiedad y la depresión.1 »El primer paso que deben dar todos sin falta es habilitar las funciones en sus teléfonos inteligentes para controlar el tiempo que pasan a diario usando cada una de las aplicaciones de sus redes sociales. Esas funciones se encuentran en Settings o Ajustes, y pueden llamarse Screen Time o “Bienestar digital y controles parentales”.... Es muy recomendable que las familias hablen entre sí y se pongan de acuerdo en cuanto a límites de tiempo para todos. El padre y la madre deben asegurarse de usar la contraseña parental cuando establezcan esos límites en el teléfono de cada niño, niña y adolescente.» Con eso termina lo que Linda, mi esposa, recomienda en este caso. El caso completo puede leerse con sólo pulsar la pestaña en www.conciencia.net que dice: «Casos», y luego buscar el Caso 820. Carlos ReyUn Mensaje a la Concienciawww.conciencia.net 1 Bruce Goldman, “Addictive potential of social media, explained [Explicación del potencial de adicción a las redes sociales],” Stanford Medicine, Scope: Beyond the Headlines [Alcance: Más allá de los titulares], Interview of [Entrevista a] Anna Lembke, MD, Dopamine Nation: Finding Balance in the Age of Indulgence [Nación de dopamina: Encontrar el equilibrio en la era de la indulgencia] (New York: Dutton, 2021) En línea 26 enero 2024.

The Peds NP: Pearls of Pediatric Evidence-Based Practice
Acute Care Faculty Series: How to Deliver a Patient Presentation in the PICU (S11 Ep. 77)

The Peds NP: Pearls of Pediatric Evidence-Based Practice

Play Episode Listen Later Dec 3, 2024 27:56


Welcome to The Peds NP Acute Care Faculty series! This series was created and peer-reviewed by national leaders in acute care PNP education collaborating with one another to meet the needs of our current and future colleagues. In the push for competency-based education where faculty verify the skills of what a student can do, rather than their knowledge, our series focuses on the application of didactic content with a practical approach so that you can learn nuances of clinical skills before you reach the bedside.    This episode reviews the features of a patient presentation in the pediatric intensive care unit (PICU) and goes in depth on how learners can incorporate trends, new findings, and summaries into a succinct discussion in family-centered rounds. After an introduction with some general best practices, the guide begins with effective pre-rounding and progresses to the step-by-step components of a PICU patient presentation. The template describes each component's contents in detail, followed immediately by an example to demonstrate the practical application of each concept… “It might sound something like this:”... This episode is a valuable tool for any pediatric provider seeking to increase their skills in succinct synthesis and patient presentations, regardless of clinical setting.   This episode was peer reviewed by The Peds NP faculty series peer review team. You can read about our novel and scholarly approach to peer review, review our faculty lineup, and learn more about the series, competency mapping, references, and show notes at www.thepedsnp.com. There was no financial support or conflicts of interest to report. Follow me on Instagram @thepedsnppodcast.  Email me at thepedsnp@gmail.com.  Remember that this isn't just a podcast, you're listening for the kids.   Authors (alphabetical): Jackie Calhoun, DNP, CRNP, CPNP-AC, CCRN, Becky Carson, DNP, APRN, CPNP-PC/AC, Lena Oliveros, MSN, CPNP-AC, Priscila Reid, DNP, APRN, FNP-C, CPNP-AC   References:  Bolick, B.N., Reuter-Rice, K., Madden, M.A., Severin, P.N. (2020). Pediatric Acute Care: A guide for Interprofessional Practice (2nd ed.). Jones & Barlett Learning. Burlington, MA.    Oubre, R. (2024). Systems versus problem-based notes. Dr. Oubre's Digest. https://droubredigest.beehiiv.com/p/systems-versus-problems-based-notes   Stanford Medicine. (nd). Coaching best practices– Presenting a patient. https://med.stanford.edu/content/dam/sm/peds/documents/Program%20Information/coaching/Coaching%20Feedback%20Summary_Presenting%20a%20Patient.pdf   UC San Diego School of Medicine. (2018). Overview and general information about oral presentation. Practical Guide to Clinical Medicine. https://meded.ucsd.edu/clinicalmed/oral.html

Moving Medicine
Cannabis use and psychiatric disorders

Moving Medicine

Play Episode Listen Later Nov 28, 2024 17:15


Board-certified physician at Stanford Medicine, Smita Das, MD, PhD, MPH, and professor and director of Addiction Sciences at the Medical University of South Carolina, Kevin Gray, MD, discuss cannabis use and its effects on mental health and psychiatric disorders, including psychosocial outcomes from use and potentiation of psychiatric disorders. Common perceptions of use of cannabis for mental health are also discussed.     ⭐⭐⭐⭐⭐

From Our Neurons to Yours
The power of psychedelics meets the power of placebo: ketamine, opioids, and hope in depression treatment | Boris Heifets & Theresa Lii

From Our Neurons to Yours

Play Episode Listen Later Nov 21, 2024 35:10 Transcription Available


Join us as we dive back into the world of psychedelic medicine with anesthesiologists Boris Heifets and Theresa Lii, who share intriguing new data that sheds light on how ketamine and placebo effects may interact in treating depression.We explore provocative questions like: How much of ketamine's antidepressant effect comes from the drug itself versus the excitement of being in a psychedelics trial? What do we know about how placebo actually works in the brain? And should we view the placebo effect as a feature rather than a bug in psychiatric treatment?Join us as we examine the complex interplay between psychoactive drugs, the brain's own opioid system, and the healing power of hope in mental health care.Related researchPreprint: Opioids Diminish the Placebo Antidepressant Response: A Post Hoc Analysis of a Randomized Controlled Ketamine Trial (medRxiv, 2024)Randomized trial of ketamine masked by surgical anesthesia in patients with depression (Nature Mental Health, 2023)Related episodesPsychedelics, placebo, and anesthetic dreams | Boris Heifets (Part 1) Psychedelics Inside Out: How do LSD and psilocybin alter perception? | Boris Heifets (Part 2)OCD and Ketamine | Carolyn RodriguezPsychedelics and Empathy: Why are psychiatrists taking a fresh look at MDMA? | Rob MalenkaRelated newsResearchers find response to ketamine depends on opioid pathways, but varies by sex (Stanford Medicine, 2024)The rebirth of psychedelic medicine (Wu Tsai Neuro, 2023)Can Psychedelic Drugs Treat Physical Pain? (Scientific American, 2022)Scientists Say A Mind-Bending Rhythm In The Brain Can Act Like Ketamine (NPR, 2020)Get in touchWe're doing some listener research and we want to hear from your neurons! Email us at at neuronspodcast@stanford.edu if you'd be willing to help out, and we'll be in touch with some follow-up questions.Episode CreditsThis episode was produced by Michael Osborne at 14th Street Studios, with production assistance by Morgan Honaker. Our logo is by Aimee Garza. The show is hostSend us a text!Thanks for listening! If you're enjoying our show, please take a moment to give us a review on your podcast app of choice and share this episode with your friends. That's how we grow as a show and bring the stories of the frontiers of neuroscience to a wider audience. Learn more about the Wu Tsai Neurosciences Institute at Stanford and follow us on Twitter, Facebook, and LinkedIn.

Hope and Help For Fatigue & Chronic Illness
EP48: How To Manage ME/CFS and Other Chronic Illnesses with Jamie Seltzer

Hope and Help For Fatigue & Chronic Illness

Play Episode Listen Later Nov 19, 2024 55:41


Learn more about INIM's Research Studies: https://www.nova.edu/nim/research-studies/index.html  Haylie Pomroy welcomes back Jamie Seltzer, the Scientific Director of MEAction for another insightful conversation about myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). They explore how personalized nutrition, pacing, and lifestyle adjustments can support the management of chronic conditions, including post-exertional malaise (PEM), long COVID, and postural orthostatic tachycardia syndrome (POTS). Jamie offers practical tips on preparing simple, healthy meals, understanding the stages of illness, and creating a less stressful environment. Together, they emphasize how small changes can significantly improve quality of life.  Whether you're living with ME/CFS, caring for someone who is, or looking to learn more about chronic illness, this episode provides valuable advice and insights. Tune in to the Hope and Help for Fatigue and Chronic Illness – How To Manage ME/CFS and Other Chronic Illnesses with Jaime Seltzer. If you are interested in joining a Gulf War Illness (GWI) trial, please complete the Recruitment Registry Form. https://redcap.nova.edu/redcap/surveys/?s=Y9YF8JJWJRK8HEKL%20&_gl=1*1fipp18*_gcl_aw*R0NMLjE3MDc5MTgwMzIuRUFJYUlRb2JDaE1JeWNyUXVfcXFoQU1WU1pCYUJSM3AyQWRBRUFBWUFTQUFFZ0s1NWZEX0J3RQ..*_gcl_au*MTg2NjgwMDQ4Ni4xNzA3MTQwNzgx  Sign up for the COVID-UPP Study: https://redcap.nova.edu/redcap/surveys/?s=RMEDJ7LKCX&_gl=1*1h830h7*_gcl_au*MTM2NDA0MTQyOS4xNzE1MDA0ODAy Jaime Seltzer is the Scientific Director at MEAction, a nonprofit advocating for those with chronic illnesses. She bridges communication between healthcare, government, and research sectors, representing ME Action globally. Additionally, Jaime collaborates with institutions like Stanford Medicine and Mayo Clinic Rochester on post-infectious chronic diseases research. She brings personal insight to her work as someone living with ME/CFS.  LinkedIn: https://www.linkedin.com/in/jaime-seltzer-b23abb14/ Twitter: https://twitter.com/exceedhergrasp1 https://twitter.com/meactnet Website: https://www.meaction.net/ Facebook: https://www.facebook.com/MEActNet/ Instagram: https://www.facebook.com/meactnet Subscribe to the MEAction Newsletter: https://www.meaction.net/subscribe/ Donate to the MEAction Network: meaction.net/donate Neuroinflammation Research Review (2019) by Jaime Seltzer: http://www.meaction.net/wp-content/uploads/2019/06/19_MEA_Revised_2019_Research_Summary_190610.pdf Pacing and Management Guides: https://www.meaction.net/resource/pacing-and-management-guide/  Ask Mayo Expert: https://www.meaction.net/2023/04/26/mecfs-algorithm-is-live/ -----------------------------  Enjoy our show? Please leave us a 5-star review so we can bring hope and help to others.  Sign up today for our newsletter. https://nova.us4.list-manage.com/subscribe?u=419072c88a85f355f15ab1257&id=5e03a4de7d This podcast is brought to you by the Institute for Neuro-Immune Medicine. Learn more about us here.   Website: https://www.nova.edu/nim/ Facebook: https://www.facebook.com/InstituteForNeuroImmuneMedicine Instagram: https://www.instagram.com/NSU_INIM/ Twitter: https://www.twitter.com/NSU_INIM #MECFS #PEM #LongCOVID #ChronicFatigue #MyalgicEncephalomyelitis #ChronicIllness #Healthcare #ChronicIllnessCare #PostExertionalMalaise #POTS #PEM #ChronicFatigueManagement #HealthPodcast 

Hope and Help For Fatigue & Chronic Illness
EP48: How To Manage ME/CFS and Other Chronic Illnesses with Jaime Seltzer

Hope and Help For Fatigue & Chronic Illness

Play Episode Listen Later Nov 19, 2024 55:39


Learn more about INIM's Research Studies: https://www.nova.edu/nim/research-studies/index.html   Haylie Pomroy welcomes back Jamie Seltzer, the Scientific Director of MEAction for another insightful conversation about myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS).   They explore how personalized nutrition, pacing, and lifestyle adjustments can support the management of chronic conditions, including post-exertional malaise (PEM), long COVID, and postural orthostatic tachycardia syndrome (POTS). Jamie offers practical tips on preparing simple, healthy meals, understanding the stages of illness, and creating a less stressful environment. Together, they emphasize how small changes can significantly improve quality of life.   Whether you're living with ME/CFS, caring for someone who is, or looking to learn more about chronic illness, this episode provides valuable advice and insights.   Tune in to the Hope and Help for Fatigue and Chronic Illness – How To Manage ME/CFS and Other Chronic Illnesses with Jaime Seltzer.   If you are interested in joining a Gulf War Illness (GWI) trial, please complete the Recruitment Registry Form. https://redcap.nova.edu/redcap/surveys/?s=Y9YF8JJWJRK8HEKL%20&_gl=1*1fipp18*_gcl_aw*R0NMLjE3MDc5MTgwMzIuRUFJYUlRb2JDaE1JeWNyUXVfcXFoQU1WU1pCYUJSM3AyQWRBRUFBWUFTQUFFZ0s1NWZEX0J3RQ..*_gcl_au*MTg2NjgwMDQ4Ni4xNzA3MTQwNzgx   Sign up for the COVID-UPP Study: https://redcap.nova.edu/redcap/surveys/?s=RMEDJ7LKCX&_gl=1*1h830h7*_gcl_au*MTM2NDA0MTQyOS4xNzE1MDA0ODAy   Jaime Seltzer is the Scientific Director at MEAction, a nonprofit advocating for those with chronic illnesses. She bridges communication between healthcare, government, and research sectors, representing ME Action globally. Additionally, Jaime collaborates with institutions like Stanford Medicine and Mayo Clinic Rochester on post-infectious chronic diseases research. She brings personal insight to her work as someone living with ME/CFS.    LinkedIn: https://www.linkedin.com/in/jaime-seltzer-b23abb14/ Twitter: https://twitter.com/exceedhergrasp1 https://twitter.com/meactnet Website: https://www.meaction.net/ Facebook: https://www.facebook.com/MEActNet/ Instagram: https://www.facebook.com/meactnet   Subscribe to the MEAction Newsletter: https://www.meaction.net/subscribe/   Donate to the MEAction Network: meaction.net/donate Neuroinflammation Research Review (2019) by Jaime Seltzer: http://www.meaction.net/wp-content/uploads/2019/06/19_MEA_Revised_2019_Research_Summary_190610.pdf   Pacing and Management Guides: https://www.meaction.net/resource/pacing-and-management-guide/   Ask Mayo Expert: https://www.meaction.net/2023/04/26/mecfs-algorithm-is-live/   -------------------------------------------------------------------------------------------------   Enjoy our show? Please leave us a 5-star review so we can bring hope and help to others.   Sign up today for our newsletter. https://nova.us4.list-manage.com/subscribe?u=419072c88a85f355f15ab1257&id=5e03a4de7d   This podcast is brought to you by the Institute for Neuro-Immune Medicine. Learn more about us here.    Website: https://www.nova.edu/nim/ Facebook: https://www.facebook.com/InstituteForNeuroImmuneMedicine Instagram: https://www.instagram.com/NSU_INIM/ Twitter: https://www.twitter.com/NSU_INIM #MECFS #PEM #LongCOVID #ChronicFatigue #MyalgicEncephalomyelitis #ChronicIllness #Healthcare #ChronicIllnessCare #PostExertionalMalaise #POTS #PEM #ChronicFatigueManagement #HealthPodcast 

Breaking Beauty Podcast
Are You Ready for Your First "Aging Spike”? Plus! “Secret Menus” at Derm Offices and The Skincare Ingredients That Will be Everywhere in 2025 with Derm Approved Podcast Host Dr. Sheila Farhang

Breaking Beauty Podcast

Play Episode Listen Later Nov 13, 2024 49:44


What if we don't age in a linear pattern, and instead, experience pronounced “bursts” at ages 44 and 60? The latest study out Stanford Medicine published in the scientific journal, Nature, has given the skincare community a lot to mull over. Today, we're welcoming double-board certified dermatologist, cosmetic surgeon and host of the Derm Approved podcast, Dr. Sheila Farhang, to help us break it all down. Listen in as Dr. Sheila explains the best way to prepare for an aging “spike” and tune in until the end to hear her predictions for what we'll all be talking about in 2025.You'll hear about:“Prejuvenation” secrets: The treatments to invest in before your next spike, and what she's *personally* stopped doing this year (buh-bye masseter Botox!)Where to click to find your best dermatologist provider, for cosmetic or medical purposes, without any spon-conIs there a “secret” menu at your dermatologist's office that we should know about?? The cocktailing injection fads that are and aren't worth trying, according to the dermDr. Sheila's response to filler fatigue, “perception drift” and where some injectors have gone way overboardGetting filler dissolved? Listen to what Dr. Sheila has to say first The surprising ingredient that she predicts will be big in 2025, beyond its gimmicky reputationThe peer-reviewed injectors seal of approval list we mention is Castle Connolly and esthetic concierge services like PersanaPssst! We were guests over on Dr. Sheila's podcast, Derm Approved, discussing how to manage tough-to-treat areas like eye bags and jowls. Tune in here to listen! For any products or links mentioned in this episode, check out our website: https://breakingbeautypodcast.com/episode-recaps/ Related episodes like this: Skin Cycling 101, Niacinamide News & More With Dermatologist Dr. Whitney BoweDermatologist Dr. Shereene Idriss Serving The Real Tea on Skincare ScamsHow-To Get On A Retinol Routine You Won't Want to Quit With Dr. Frauke Neuser PROMO CODES: When you support our sponsors, you support the creation of Breaking Beauty Podcast! OUAIGet on your OUAI to save for the holiday. Go to theouai.com for 15% off site wide and enter promo code BEAUTY15.MASTERCLASSRight now, our listeners get an additional 15% off any annual membership at MASTERCLASS.com/BEAUTY. QUINCEGet cozy in Quince's high-quality wardrobe essentials. Go to Quince.com/Beauty to get free shipping on your order and 365-day returns. Get social with us and let us know what you think of the episode! Find us on Instagram, Tiktok, Twitter. Join our private Facebook group, or give us a call and leave us a voicemail at 1-844-227-0302. *Disclaimer: Unless otherwise stated, all products reviewed are gratis media samples submitted for editorial consideration.* Hosts: Carlene Higgins and Jill Dunn Theme song, used with permission: Cherry Bomb by Saya
 Produced by Dear Media Studio See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Continuum Audio
Orofacial Pain With Drs. Meredith Barad and Marcela Romero-Reyes

Continuum Audio

Play Episode Listen Later Nov 6, 2024 24:39


Orofacial pain comprises many disorders with different etiologies and pathophysiologies. A multidisciplinary approach combining medication, physical therapy, and procedural and psychological strategies is essential in treating patients with orofacial pain. In this episode, Teshamae Monteith, MD, FAAN, speaks with Meredith Barad, MD; Marcela Romero-Reyes, DDS, PhD, authors of the article “Orofacial Pain,” in the Continuum® October 2024 Pain Management in Neurology issue. Dr. Monteith is the associate editor of Continuum® Audio and an associate professor of clinical neurology at the University of Miami Miller School of Medicine in Miami, Florida. Dr. Barad is a clinical associate professor of anesthesiology, perioperative and pain medicine, and neurology and neurological sciences and codirector of the Stanford Facial Pain Program at Stanford Medicine in Stanford, California. Dr. Romero-Reyes is a clinical professor and director of the Brotman Facial Pain Clinic and Department of Neural and Pain Sciences at the University of Maryland in Baltimore, Maryland. Additional Resources Read the article: Orofacial Pain Subscribe to Continuum: shop.lww.com/Continuum Earn CME (available only to AAN members): continpub.com/AudioCME Continuum® Aloud (verbatim audio-book style recordings of articles available only to Continuum® subscribers): continpub.com/Aloud More about the American Academy of Neurology: aan.com Social Media @ContinuumAAN Host: @headacheMD Guest: @meredith_barad facebook.com/continuumcme Full episode transcript available here Dr Jones: This is Dr Lyell Jones, Editor-in-Chief of Continuum, the premier topic-based neurology clinical review and CME journal from the American Academy of Neurology. Thank you for joining us on Continuum Audio, which features conversations with Continuum 's guest editors and authors who are the leading experts in their fields. Subscribers to the Continuum Journal can read the full article or listen to verbatim recordings of the article and have access to exclusive interviews not featured on the podcast. Please visit the link in the episode notes for more information on the article, subscribing to the journal, and how to get CME. Dr Monteith: This is Dr Teshamae Monteith, associate editor of Continuum Audio. Today I'm interviewing Drs Meredith Barad and Marcela Romero-Reyes about their article on oralfacial pain, which appears in the October 2024 Continuum issue on pain management and neurology. Welcome to the podcast, ladies. How are you?  Dr Barad: Excellent.  Dr Romero-Reyes: Fine, happy to be here.  Dr Monteith: I am so happy to see you. I mean, I think both of you I've known for like ten years. Dr Romero-Reyes: Yeah.  Dr Barad: Yes.  Dr Monteith: So why don't you introduce yourselves? While I know you, our audience, some of them, may not know you.  Dr Romero-Reyes: I'm Dr Marcella Romero Reyes. I am a neuropathial pain specialist, clinical professor, and director of the Provident Special Pain Clinic here in the University of Maryland School of Dentist. Dr Monteith: Excellent.  Dr Barad: My name is Meredith Barad. I'm a clinical associate professor at Stanford and I work- I'm the codirector of our headache and facial pain clinic in the Stanford pain management clinic. Dr Monteith: Well, first of all, thank you for writing this article. It is extremely detailed and up-to-date and very informative. And in neurology, I think we don't get enough pain management. I'm interested in both of your backgrounds and, you know, what led you even to become an expert in this area? And both of you have complementary areas. I think we can see in the quality of this article. But why don't we start with you, Dr Romero-Reyes? Dr Romero-Reyes: Well, for me to get interested in orofacial pain, I will say more than an interest was like a calling that I wanted to take care of this patient population. So, as you know, my background is dentistry and at that time I was very interested in patients with complex medical issues. And was the time I was- I started to be interested in temporomandibular disorders. But what really picked completely my attention was the first time I saw a patient with trigeminal neuralgia. This was my last year in dental school. This patient already had, like, almost a full upper quadrant of teeth extracted where pain was not resolved. So when the patient came to us and I did my exam and, you know, and I triggered the pain, the sharp shoot electrical pain, that really broke my heart. And I took an x-ray and I didn't find anything that will explain it was something wrong until I talked to my professor and he said, no, this is medical. There's nothing wrong with it, with that tooth and needs to be, you know, followed with proper management and medication. And for me, that was like, wow, what a proper diagnosis and proper management can take care of these of these patients. And when the patient got better, that really said, oh, you know, I want to do this.  Dr Monteith: That's a crazy story. It's always that last patient of the day.  Dr Romero-Reyes: And you know, think about it, at least in dentistry at that time, I learned about trigeminal neuralgia from a book, right, my classes. But when you see the patient, this is it. That completely, you know, made me say yes, I want to study this.  Dr Monteith: Yeah. And unfortunately, that's not an uncommon scenario where patients with trigeminal neuralgia get, you know, their extractions and pain can sometimes be more complicated. What about you, Dr Barad? Dr Barad: Well, I guess I'm sort of like the opposite. So as a neurologist and a trained pain physician, I saw a lot of patients with neuralgic pain and headache pain, but I also saw many patients who would say, I have TMJ. And as, as Dr Romero has educated us, that's like saying I have shoulder or I have knee. But I quickly realized that I needed to work with a multidisciplinary team to really understand more about orofacial pain. It's not just neuralgic. There are other ideologies. And so that's how we started working together and that's how we practice in our clinic at Stanford. Dr Monteith: So, why don't you tell us about the objectives of this article? Dr Barad: I think our objectives were to help the neurologist broaden the differential diagnosis on facial pain to encompass below the nose, the oral cavity, the temporal mandibular joint. And to just think more broadly about facial pain and to understand some of the more recent diagnostic criteria that have been developed for facial pain and to- how to diagnose properly and how to begin treatment for some of the other conditions that are non-neurologic.  Dr Romero-Reyes: And I think I will ask about what Dr Barad say that also to bring awareness to the neurologist about the vast classification of oral facial pain disorder, craniofacial and orofacial. I think that was also a key thing too. And also, to show how well we can work together, you know, the multi-disciplinary management that is indicated for these cases. Dr Monteith: Cool. And you mentioned some of the new diagnostic criteria. I want to talk just briefly about the new international classification of orofacial pain, ICOP. When did that come out and what was the process there in really fine-tuning the diagnosis of orofacial pain disorders? Dr Romero-Reyes: So, in 2019 the orofacial head pain especially interest group of the International Association for the Study of Pain, the International Network for Orofacial Pain and Related Disorders methodology and the American Academy of Orofacial Pain and the International Headache Society. They partnered together to develop to develop this international classification of orofacial pain. And these, I think- it's such a great effort, you know, all the main people doing pain about this area, and goes very well together with the international classification of headache disorders. So, for example, you know, some disorders that International Classification of Headache Disorders doesn't present such as and the ICOP, International Classification of Orofacial Pain, presents, like the persistent idiopathic dental Viola pain. You have it in the ICOP. It's not, you know, mentioned in the in the International Classification of Headache Disorders, as well as, also we have the- I think it's item number five, the orofacial representations headache disorder or primary headache disorder. The ICOP gives you a nice, clean diagnostic criteria.  Dr Monteith: So, I guess I would ask Dr Barad with this classification in mind, how useful is it in neurology practice? And I know obviously you see patients with pain, but how useful even in managing patients with headache? Dr Barad: I think it's great because I've had a lot of dentists and ENT doctors who have started referring patients to me because they've realized that they've increased their awareness about orofacial pain and realized that pain in the sinuses, for example, accompanied by light sensitivity and sound sensitivity and rhinorrhea, may not be a recurrent monthly sinus infection. And so that kind of broadens our awareness of these of these disorders. And it's been, it's brought new patients into my clinic that we can help and treat. So that's been exciting.  Dr Monteith: And what about in the world of dentistry? Obviously, I think people in orofacial pain worlds are highly attuned to this, but I would hope this would hopefully have been disseminated into dentists and regular practice at C patients with trigeminal neuralgia. Dr Romero-Reyes: Going back for the, what you were discussing about the ICOP. So, it's what we're trying now as a new specialty. Well that we have been for the last four years, but finally in 2020 we have been recognized by the American Mental Association to disseminate this knowledge. But also, you know, can you imagine in in the realm in orofacial pain or dentistry have a patient with this recurrent pain, phonophobia, photophobia, throbbing dental pain is throbbing, but it's nothing wrong with your tooth. And that did they tell you that actually you have an orofacial or facial migraine or a neurovascular or facial pain. How crazy, right? And that is managed with migraines therapy. So it really, you know, to make you think like that. Wow, so these weird tooth things that used to come every week or these with facial pain, it's nothing to deal with, you know, with my teeth or any structure, you know, inside my mouth. Dr Barad: It sounds to me like what you're saying is that we've, this has encouraged patient education as well, not only interdisciplinary education, but really helping provide an explanation for the patient about what is going on with them. So rather than just getting sent away to another tertiary specialist, the patient is getting a more robust understanding of what's going on.  Dr Romero-Reyes: And going back to what you were saying about trigeminal neuralgia, you know, at least in dentistry also we're teaching now a new awareness like for two things, right? What about from the neurology setting? The patient has captured electrical pain. The trigger is intraoral. If it's pain inside your mouth, the first practitioner you're going to see who will be maybe the dentist that the dentist knows that could be a possibility of a disorder that doesn't deal with teeth, but also, it's important and we discussed that in our paper. What about that actually that weird trigger actually, it's not a general. What about if it's a cracked tooth has that singing sensation too. So, you see, it's two ways; one, to teach dentist to learn about this disorder and you know, we have learned, but you know, it's much more awareness now that this is great that, you know, these disorders you're not going to treat with dental procedures. Right? It's medical and vice versa, that the neurologist also has the awareness that oh, central trigger. Have you gone to the to the dentist? Have you checked that out? Dr Monteith: So what should neurologist know about dental sources of pain? Dr Barad: Well, maybe they should read the paper?  Dr Romero-Reyes: Yeah. Yeah, you need to read the paper. Yeah.  Dr Monteith: Top three, don't treat this with gabapentin.  Dr Romero-Reyes: Like well, dental pain is not going to be resolved with gabapentin. That would need to make a diagnosis if and you know it's that examination that come comes with a radiographic evidence that shows that maybe could be a cavity or could be a problem. You know in the in the practical tissues of the tooth that is given a symptomatology. Not only dental could be a lot of different disorders inside there now that can produce pain that also the readers can check our paper and learn about and see the wonderful interesting pictures that we have added there. Dr Monteith: Yeah. And so why don't we talk a little bit about TMD disorders and what is the new thinking around these conditions? Dr Romero-Reyes: Well, I will say for the last decade, maybe a little bit more has been a change in the evidence. They evidence based understanding of the theologia pathophysiologist and for mandibular disorders. Imagine that what's the shift in the in the paradigm that in dentistry prevails for a long, long time. That is that really focus and I will call it the pathological mechanistic point of view. What I mean by that I was focusing your bite, your occlusion, how the relation between in your maxilla mandible. That was the only issues that would create in temporomandibular disorders. So now we know that temporomandibular disorders are complex, are multifactorial and you need to understand them and see them within a biopsychosocial framework. And this dictate the main way to management for the primary way that we start will be conservative, reversible and basing evidence that the best evidence available that we have. Dr Monteith: And what about for trigeminal neuralgia? Is there newer kind of classification around trigeminal neuralgia? and what are some key points that we should consider when diagnosing these patients and treating these patients, Dr Barad?  Dr Barad: There haven't been any new diagnostic criteria, but I would say that there's been an increased awareness that classical trigeminal neuralgia is more likely than not related to neurovascular compression or we should say, maybe I should say neurovascular contact or compression. There is a developing grading system of that. That's an evolution as we speak. I think it's an exciting time for facial neuralgia because it's opened the door for us to look at other neuralgia also as vascular compressions and to think about how we can treat them with decompression or possibly with peripheral nerve stimulation or medicine or Botox. Or who knows what's the future is going to hold? But it is I think a change in the way we are thinking about the definition of neuralgia of, of trigeminal neuralgia in that is caused by a compression which is different than other neuralgia in other parts of the body. I should, I just want to classify there's about maybe ten twelve percent of people who present with classical trigeminal neuralgia who there is not evidence on imaging of a vascular contact or compression. But the majority of cases do seem to have some somewhere in the spectrum from contact to compression.  Dr Monteith: Even contact I find to be a bit vague sometimes say, well, thanks for letting me know that they're touching. But and then some of the neurosurgeons have different perspective when you open the patient up. So, I didn't know about the grading.  Dr Barad: Yeah, I think you've hit on it exactly like that is a big problem in the field right now. How do we understand what patients will be the best patients for surgery? And it used to be that you have the classical trigeminal neurologist symptomology plus some imaging that shows something versus nothing. And now we're getting into parsing out the imaging and trying to understand who's the best candidate for that with the imaging.  Dr Monteith: Dr Romero, anything to add?  Dr Romero-Reyes: No, that I agree about that, you know, and I think now maybe for the patients that I have seen with that, because under partial pain settings, sometimes we're the ones that, oh, actually what you have is trigeminal neuralgia idea, you know, so we start to have our small disciplinary management, but you know, when they come out, I already have an MRI doctor, but, and they say that these are compression, but what degree? And some patients that they don't have symptoms can have a compression. And I'm thinking maybe right that later on when we have more time and maybe nicer imaging, we're going to really find out or if it's the development angle is the measurement has some other characteristics, who knows. So, I think for trigeminal neuralgia, the things is still evolving, right? For our understanding. I have to help us to make a more- I will not say definitive diagnosis, but maybe some parameters will change in the future. Dr Monteith: So now we have a lot of people listening, international folks listening, and they always want some treatment, a tip, some clinical tips. So, can you give us a little bit of clinical insight to how to treat patients with trigeminal neuralgia and when you're seeing patients for second and third opinions, what might you see that may explain why their pain is not well controlled? We all get into interdisciplinary care, but in terms of pharmacology? Dr Barad: I think people are a little reluctant to use some of these medications that neuromodulating medications because, in general, it's an older population and they're rightly worried about falls and dizziness and confusion and low sodium. And so, I think they hesitate to go to the doses that are needed to help with pain control. So, a lot of our, my initial management is gingerly and gently titrating that to try to get to see if we can get control of the pain. Dr Monteith: Dr Romero?  Dr Romero-Reyes: I could add, for example, one thing that I in the realm of facial pain addition to pharmacology. Let's say that we have a patient with that intraoral trigger and we were able to localize that intraoral trigger. Sometimes we can even also use topical medication. And in the topical medication we can use, for example, an anticonvulsant, let's say gabapentin, oxcarbazepine for example, to add in the cream. And we use, we call it a neurosensory stent in my looks like a Nygard, but it's not a Nygard that can cover that area. So, the patient can add that cream very delimited in that area. And that helps, you know, can help with the pain sometimes. What we can find is that, at least in my, in my experience, and that when we add a topical, maybe we don't need to increase as much. The systemic medication, of course, depends from case to case.  Dr Monteith: So those are two great tips. Not being afraid to push those doses up in a safe manner and maybe with monitoring as well as of maybe utilizing more topicals. And I think we could probably hear a lot more from you on topicals at some other point. But thank you also for the table. I think it's, it's really nice the way all the treatments are laid out. So what other cranial neuralgia advances have there been? Dr Barad: I would say the main advancements have been in applying the knowledge that neurosurgeons have learned from microvascular decompression of the trigeminal nerve, to the glossopharyngeal nerve, to the geniculate nerve, and really trying to optimize imaging and optimize neurosurgical techniques to try to treat these neuralgias. If the patient has failed medicine, if the patient is a good candidate for surgery and if the patient desires that. Dr Monteith: Great. So now let's talk about multidisciplinary approaches. I know both of you are big fans of that, and you may do things a little bit differently at your institution, especially with your background. So maybe Dr Romero, do you want to tell us about your experience? And then we'll have Dr Brad. Dr Romero-Reyes: But in my experience from study management, let's say depend, of course, also the started we're talking about. But let's say for example about temporomandibular disorders, you know that for TMD is one of these overlapping pain conditions and we know that TMD is common with primary headache disorders, especially migraine. So, if we're able to utilize, you know, the expertise of neurologist specializing headache. With me, for example, or a facial pain person that is that is helping you manage a patient with this comorbidity. This is super effective because we know the presence of TMD in a migraineur can help the disorder to, to progress some more chronic form. So, you see, this is super important and effective to provide, you know, optimal care for the patient. For example, in the patients that I do see with neuralgias, like in addition to trigeminal neuralgia, let's say nervous intermediates neuralgia, that sometimes they can come to me like, oh, the pain is in my ear and my EMT or, or I think maybe it's my TMJ and for the pain is charged shooting inside the ear doesn't follow the for the diagnosis of temporomandibular disorders. And I can maybe help the patient to get a proper imaging or already penalize it with a neurologist to make sure. And maybe at least my way will be maybe I'm the one that can catch those disorders and help, you know, the patient to go for the next step. Dr Barad: I think Marcella, Dr Romero-Reyes, hit on a nice point that maybe this group is not as familiar with and that is that temporal mandibular dysfunction TMD is a, is one of the disorders that we call chronic overlapping pain conditions or COCPs. And those include headache. it's not, it's not specified fibromyalgia, irritable bowel syndrome, chronic pelvic pain and several other chronic pain syndromes. And they suggest a central sensitization to one's pain. And the way that we treat centrally sensitized pain is not just through medications, it's in a biopsychosocial framework because we see much higher rates of depression and anxiety in this group. And so, using a pain psychologist to help the patient develop coping strategies to help them manage their pain, using a physical therapist to help them learn this, the stretching exercises and using medications to help with not only with their pain syndrome, but also sometimes with their psych comorbidities. And then additionally, procedures sometimes play a role in the process to help usually turn down the pain. Interestingly, when we look at trigeminal neuralgia, we see much less overlapping pain disorders. It's much rarer to see somebody with TN who has other COCPs or the kind of chronic levels of depression and anxiety that we see in these patients. So, the approach is very different, and I think it requires the use of a multidisciplinary team to help guide the treatment pathways for these patients. Dr Monteith: Today, I've been interviewing Drs Meredith Barad and Marcelo Romero-Reyes, whose article on orofacial pain appears in the most recent issue of Continuum on pain management and neurology. Be sure to check out Continuum Audio episodes from this and other issues. And thank you to our listeners for joining today. Dr Monteith: This is Dr Teshamae Monteith, associate editor of Continuum Audio. If you've enjoyed this episode, you'll love the journal, which is full of in-depth and clinically relevant information important for neurology practitioners. Use this link in the episode notes to learn more and subscribe. AAN members, you can get CME for listening to this interview by completing the evaluation at continpub.com/AudioCME. Thank you for listening to Continuum Audio.

Moving Medicine
How addictive is cannabis?

Moving Medicine

Play Episode Listen Later Oct 31, 2024 16:21


Learn about potential for cannabis addiction, withdrawal symptoms, and overdose. Board-certified physician at Stanford Medicine, Smita Das, MD, PhD, MPH, reviews screening, models of care, and treatment for cannabis use disorder.     ⭐⭐⭐⭐⭐

Pear Healthcare Playbook
Dr. Muthu Alagappan, CEO and Founder of Counsel, on defining a new healthcare paradigm in asynchronous care

Pear Healthcare Playbook

Play Episode Listen Later Oct 28, 2024 44:22


Today, we're excited to get to know Dr. Muthu Alagappan, CEO and Founder of Counsel, the modern solution for access to care. Before founding Counsel, Muthu was the CMO of Notable Health for almost 4 years and was an Attending Physician at Beth Israel Deaconess Medical Center and UCSF Medical Center. He graduated with his MD from Stanford Medicine and (fun fact!) was also the Student Commencement Speaker for his graduating class.Founded in 2023, Counsel provides patients with high-quality, personalized medical advice from expert doctors within minutes. Counsel recently announced $11M in seed funding from investors like A16z, Floodgate, Asymmetric Capital and Pear VC! We're proud to be partners to Counsel!

The Mental Breakdown
About Those Teenagers

The Mental Breakdown

Play Episode Listen Later Oct 16, 2024 32:31


Welcome to The Mental Breakdown and Psychreg Podcast! Today, Dr. Berney and Dr. Marshall discuss some of the challenges associated with raising teenagers. Read the articles from Stanford Medicine here and from the Child Mind Institute here. You can now follow Dr. Marshall on twitter, as well! Dr. Berney and Dr. Marshall are happy to announce the release of their new parenting e-book, Handbook for Raising an Emotionally Healthy Child Part 2: Attention. You can get your copy from Amazon here. We hope that you will join us each morning so that we can help you make your day the best it can be! See you tomorrow. Become a patron and support our work at http://www.Patreon.com/thementalbreakdown. Visit Psychreg for blog posts covering a variety of topics within the fields of mental health and psychology. The Parenting Your ADHD Child course is now on YouTube! Check it out at the Paedeia YouTube Channel. The Handbook for Raising an Emotionally Health Child Part 1: Behavior Management is now available on kindle! Get your copy today! The Elimination Diet Manual is now available on kindle and nook! Get your copy today! Follow us on Twitter and Facebook and subscribe to our YouTube Channels, Paedeia and The Mental Breakdown. Please leave us a review on iTunes so that others might find our podcast and join in on the conversation!

Power On Your Plate
Episode 120 - ME/CFS in Action: Transforming Chronic Illness Care

Power On Your Plate

Play Episode Listen Later Sep 17, 2024 60:09


Get my nutrition and supplement programs for the best results. PLUS Get 20% off when you buy from my shop! https://hayliepomroy.com/podcast   In this episode, I'm thrilled to welcome back Jamie Seltzer, Director of Scientific and Medical Outreach at the MeAction Network. Jamie returns to share more about living with myalgic encephalomyelitis (ME/CFS), offering real-life experiences and practical tips in managing and treating its symptoms. Jaime goes in-depth with ME/CFS breaking down its impact on the body such as post-exertional malaise and cognitive impairment and how these impact daily life. Whether you're living with ME/CFS, supporting someone who is, or just want to deepen your understanding, this conversation with Jamie Seltzer offers valuable insights and strategies that can make a real difference. Tune in to this week's episode of Fast Metabolism Matters - ME/CFS in Action: Transforming Chronic Illness Care with Jaime Seltzer.   Enjoy this episode? Subscribe to Fast Metabolism Matters and leave a 5-star review.   Sign up for the 10-Day Cleanse Challenge here! https://hayliepomroy.com/cleanse    Get a FREE hard copy of the Fast Metabolism Diet book! https://hayliepomroy.com/freebook   Become a certified Fast Metabolism Health Coach NOW! https://hayliepomroy.com/fmdc   Become a member, FREE for 30 days! https://hayliepomroy.com/member Jaime Seltzer is the Director of Scientific and Medical Outreach at MEAction, a nonprofit advocating for those with chronic illnesses. She bridges communication between healthcare, government, and research sectors, representing ME Action globally. Additionally, Jaime collaborates with institutions like Stanford Medicine and Mayo Clinic Rochester on post-infectious chronic diseases research. She brings personal insight to her work as someone living with ME/CFS.   LinkedIn: https://www.linkedin.com/in/jaime-seltzer-b23abb14/ Twitter: https://twitter.com/exceedhergrasp1 https://twitter.com/meactnet Website: https://www.meaction.net/ Facebook: https://www.facebook.com/MEActNet/ Instagram: https://www.facebook.com/meactnet   Subscribe to the MEAction Newsletter: https://www.meaction.net/subscribe/   Donate to the MEAction Network: meaction.net/donate Neuroinflammation Research Review (2019) by Jaime Seltzer: http://www.meaction.net/wp-content/uploads/2019/06/19_MEA_Revised_2019_Research_Summary_190610.pdf #MECFS #PEM #LongCOVID #ChronicFatigue #MyalgicEncephalomyelitis #ChronicIllness #Healthcare #ChronicIllnessCare #PostExertionalMalaise #Nutrition #Supplements #ChronicFatigueManagement #HealthPodcast  

Fast Metabolism Matters with Haylie Pomroy
Episode 120 - ME/CFS in Action: Transforming Chronic Illness Care

Fast Metabolism Matters with Haylie Pomroy

Play Episode Listen Later Sep 17, 2024 60:09


Get my nutrition and supplement programs for the best results. PLUS Get 20% off when you buy from my shop! https://hayliepomroy.com/podcast   In this episode, I'm thrilled to welcome back Jamie Seltzer, Director of Scientific and Medical Outreach at the MeAction Network. Jamie returns to share more about living with myalgic encephalomyelitis (ME/CFS), offering real-life experiences and practical tips in managing and treating its symptoms. Jaime goes in-depth with ME/CFS breaking down its impact on the body such as post-exertional malaise and cognitive impairment and how these impact daily life. Whether you're living with ME/CFS, supporting someone who is, or just want to deepen your understanding, this conversation with Jamie Seltzer offers valuable insights and strategies that can make a real difference. Tune in to this week's episode of Fast Metabolism Matters - ME/CFS in Action: Transforming Chronic Illness Care with Jaime Seltzer.   Enjoy this episode? Subscribe to Fast Metabolism Matters and leave a 5-star review.   Sign up for the 10-Day Cleanse Challenge here! https://hayliepomroy.com/cleanse    Get a FREE hard copy of the Fast Metabolism Diet book! https://hayliepomroy.com/freebook   Become a certified Fast Metabolism Health Coach NOW! https://hayliepomroy.com/fmdc   Become a member, FREE for 30 days! https://hayliepomroy.com/member Jaime Seltzer is the Director of Scientific and Medical Outreach at MEAction, a nonprofit advocating for those with chronic illnesses. She bridges communication between healthcare, government, and research sectors, representing ME Action globally. Additionally, Jaime collaborates with institutions like Stanford Medicine and Mayo Clinic Rochester on post-infectious chronic diseases research. She brings personal insight to her work as someone living with ME/CFS.   LinkedIn: https://www.linkedin.com/in/jaime-seltzer-b23abb14/ Twitter: https://twitter.com/exceedhergrasp1 https://twitter.com/meactnet Website: https://www.meaction.net/ Facebook: https://www.facebook.com/MEActNet/ Instagram: https://www.facebook.com/meactnet   Subscribe to the MEAction Newsletter: https://www.meaction.net/subscribe/   Donate to the MEAction Network: meaction.net/donate Neuroinflammation Research Review (2019) by Jaime Seltzer: http://www.meaction.net/wp-content/uploads/2019/06/19_MEA_Revised_2019_Research_Summary_190610.pdf #MECFS #PEM #LongCOVID #ChronicFatigue #MyalgicEncephalomyelitis #ChronicIllness #Healthcare #ChronicIllnessCare #PostExertionalMalaise #Nutrition #Supplements #ChronicFatigueManagement #HealthPodcast  

No One is Coming to Save Us
Climate Change Is A Childcare Issue

No One is Coming to Save Us

Play Episode Listen Later Sep 12, 2024 24:39


Climate change is not just an issue for our children's children. We are already feeling its effects today. Gloria talks to two experts who lived through historic California wildfires and droughts in recent years. Dr. Lisa Patel, a pediatrician and clinical associate professor at Stanford Medicine, tells Gloria about how scorching heat waves and wildfire pollutants can trigger asthma in children. She also advises how parents and schools can be better prepared for increasingly hot days. Then, we hear from Susan Gilmore, the director of an early education center in Northern California. As public schools closed down, Susan and her team quickly reopened so families could safely send their kids to class. Special thanks to our partners who have made this season possible!  This series is produced with Neighborhood Villages. Neighborhood Villages is a Massachusetts-based systems change nonprofit. It envisions a transformed, equitable early childhood education system that lifts up educators and sets every child and family up to thrive. In pursuit of this vision, Neighborhood Villages designs, evaluates, and scales innovative solutions to the biggest challenges faced by early childhood education providers and the children and families who rely on them, and drives policy reform through advocacy, education, and research. Visit www.neighborhoodvillages.org to learn more.  This season was made possible with generous support from Imaginable Futures, a global philanthropic investment firm working with partners to build more healthy and equitable systems, so that everyone has the opportunity to learn and realize the future they imagine. Learn more at www.imaginablefutures.com. This series is presented by The J. Willard and Alice S. Marriott Foundation. This series is presented by the Bainum Family Foundation. Through their WeVision EarlyEd initiative, they are elevating the voices of families and early childhood professionals, their “proximity experts,” to generate equitable and practical solutions to make the ideal vision of child care in America real. You can learn more at wevisionearlyed.org.  This season is presented by The Conrad N. Hilton Foundation, an organization working to improve the lives of individuals living in poverty and experiencing disadvantage throughout the world. Learn more at hiltonfoundation.org.  Follow No One is Coming to Save Us wherever you get your podcasts, or listen ad-free on Amazon Music with your Prime Membership. You can also get premium content and behind the scenes material by subscribing to Lemonada Premium on Apple Podcasts.  Laugh, cry, be outraged, and hear solutions! Join our community: https://www.facebook.com/groups/nooneiscomingtosaveus.  Stay up to date with us on X, Facebook and Instagram at @LemonadaMedia. Want to become a Lemonada superfan? Join us at joinsubtext.com/lemonadasuperfan.   Click this link for a list of current sponsors and discount codes for this and all other Lemonada series: lemonadamedia.com/sponsors. To follow along with a transcript, go to lemonadamedia.com/show/ shortly after the air date.See omnystudio.com/listener for privacy information.

From Our Neurons to Yours
Why new Alzheimer's drugs don't work | Mike Greicius, Stanford University School of Medicine

From Our Neurons to Yours

Play Episode Listen Later Sep 12, 2024 25:48 Transcription Available


In the past few years, Big Pharma has released not one, but three new treatments for Alzheimer's disease. Aducanemab (2021), Lecanemab (2023), and Donanemab (2024), are the first treatments to effectively clear the brain of amyloid plaques — the sticky protein clumps whose build-up in the brain has defined the disease for decades. The problem? They may not help patients at all.Today's guest, Stanford neurologist Mike Greicius, considers the new amyloid-clearing drugs a major disappointment — and worse, says they likely do more harm than good for patients.Despite this critique, Greicius, thinks that the next few years will be an exciting time for novel Alzheimer's therapies, as growing biological understanding of Alzheimer's risk and resilience bear fruit with promising new approaches to treatment.Learn More:Greicius is the Iqbal Farrukh and Asad Jamal Professor of Neurology and Neurological Sciences at Stanford Medicine, and a member of the Knight Initiative for Brain Resilience and Alzheimer's Disease Research Center at Stanford University.Amyloid Drug Skepticism:Substantial Doubt Remains about the Efficacy of Anti-Amyloid Antibodies(Commentary, Journal of Alzheimer's Disease, 2024)New Drug Approved for Early Alzheimer's (New York Times, 2024)Alzheimer's drug adoption in US slowed by doctors' skepticism (Reuters, 2024)One step back: Why the new Alzheimer's plaque-attack drugs don't work (Stanford Medicine Scope Blog, 2024)Alzheimer's Genetics Research:Knight-funded research uncovers gene mutations that may prevent Alzheimer's Disease (Knight Initiative for Brain Resilience, 2024)Why is a common gene variant bad for your brain? (Stanford Medicine Magazine, 2024)Scientists find genetic Alzheimer's risk factor tied to African ancestry (Stanford Medicine, 2023)Episode CreditsThis episode was produced by Michael Osborne, with production assistance by Morgan Honaker, and hosted by Nicholas Weiler. Art by Aimee Garza.Send us a text!Thanks for listening! If you're enjoying our show, please take a moment to give us a review on your podcast app of choice and share this episode with your friends. That's how we grow as a show and bring the stories of the frontiers of neuroscience to a wider audience. Learn more about the Wu Tsai Neurosciences Institute at Stanford and follow us on Twitter, Facebook, and LinkedIn.

From Our Neurons to Yours
Depression's distinctive fingerprints in the brain | Leanne Williams, Stanford University

From Our Neurons to Yours

Play Episode Listen Later Aug 29, 2024 28:11 Transcription Available


Getting help for depression can be like purgatory. Setting aside for a moment the stigma and other barriers to seeking treatment in the first place, finding the right combination of medication and/or therapy can be a months- or years-long process of trial and error. And for about one third of people, nothing seems to work.Today we're talking with Dr. Leanne Williams, the founding director of the Stanford Center for Precision Mental Health and Wellness and Vincent V.C. Woo Professor in the Stanford Department of Psychiatry and Behavioral Sciences. Williams and her team have recently used brain imaging and machine learning techniques to identify six distinct "biotypes" of depression — each of which may require a different approach to treatment. Beyond setting the stage for more targeted therapies, better understanding the biology behind the disease could finally cut through the stigma of one of the world's most common brain disorders.Learn moreWilliams' Personalized and Translational Neuroscience Lab (PANlab)The Stanford Center for Precision Mental Health and WellnessSix distinct types of depression identified in Stanford Medicine-led study(Stanford Medicine, 2024)Personalized brain circuit scores identify clinically distinct biotypes in depression and anxiety (Nature Medicine, 2024)Brain scans could help personalize treatment for people who are depressed or suicidal (Science, 2022)Williams' scientific publicationsEpisode CreditsThis episode was produced by Michael Osborne, with production assistance by Morgan Honaker, and hosted by Nicholas Weiler. Art by Aimee Garza.Send us a text!Thanks for listening! If you're enjoying our show, please take a moment to give us a review on your podcast app of choice and share this episode with your friends. That's how we grow as a show and bring the stories of the frontiers of neuroscience to a wider audience. Learn more about the Wu Tsai Neurosciences Institute at Stanford and follow us on Twitter, Facebook, and LinkedIn.

Shine Without Shame
Psychoactive Drugs and Mental Health: Trends, Research & Lifestyle Pt 1

Shine Without Shame

Play Episode Listen Later Aug 29, 2024 35:33


Part 1: Sam Vaillancourt is currently an academic researcher in the lab of Boris Heifets at Stanford Medicine. In lab, he studies how MDMA, ketamine, and psilocybin can be harnessed as therapeutics for brain disorders like depression and PTSD.Sam and I discuss his research with psychoactive drugs in clinical and therapeutic settings as potential tools that may benefit mental health.  We also talk about the possible trends of psychoactive drug use outside of supervised settings and the risks involved.  In part 1 of this conversation, we begin to explore how everyday lifestyle choices can play a role in metal health and overall wellness. FOLLOW:Host: Tiffany WaltersInstagram: @lifecoachforhumanityWebsite: https://lifecoachforhumanity.com/Guest: Sam VaillancourtWork: https://heifetslab.stanford.edu/You can view all video recordings at: https://bit.ly/2JYGe8S

The Brian Lehrer Show
Later-In-Life Aging Spurts

The Brian Lehrer Show

Play Episode Listen Later Aug 26, 2024 15:33


Stanford Medicine researchers recently found that we undergo two periods of rapid molecular aging during our life span, averaging around age 44 and age 60. Listeners call in to share how their bodies changed during these time periods. 

KQED’s Forum
What Science Says About Ketamine's Risks and Benefits

KQED’s Forum

Play Episode Listen Later Aug 26, 2024 57:42


Ketamine is perhaps best known as a party drug, and it has long been used in hospitals as an anesthetic. In recent years, it has also been touted as a promising, experimental psychiatric treatment. But when Friends actor Matthew Perry overdosed on ketamine last year, it exposed a network of unregulated clinics and unscrupulous doctors distributing the drug for off-label uses. In this hour, we'll talk with experts about what we know — so far — about ketamine's efficacy and safety. Guests: Smita Das, clinical associate professor of psychiatry and behavioral sciences, Stanford Medicine; vice president of complex care and psychiatry, Lyra Health Gerard Sanacora, professor of psychiatry and director, Yale Depression Research Program at the Yale School of Medicine

The Future of Everything presented by Stanford Engineering
Best of: A more thoughtful approach to technology can improve medical care

The Future of Everything presented by Stanford Engineering

Play Episode Listen Later Aug 9, 2024 28:02


Today, we're re-running a fascinating conversation with Sara Singer, a Stanford professor of medicine, and an expert on integrated healthcare. Anyone who's had to navigate the healthcare system knows it's extremely complex, and care can often feel disjointed or inefficient. In this episode, Sara highlights new technologies that could improve integration within the healthcare system, ultimately enhancing a practitioners' ability to care for patients. We hope you'll take another listen and enjoy.Episode Reference Links:Stanford Profile: Sara SingerConnect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads or Twitter/XConnect with School of Engineering >>> Twitter/XChapters:(00:00:00) IntroductionRuss Altman introduces guest Sarah Singer, a professor of medicine and organizational behaviour at Stanford University(00:02:25) Defining Integrated CareThe concept of integrated care and its significance in improving patient experience.(00:03:37) Global Implementation of Integrated CareThe global challenges and successes in implementing integrated care.(00:04:45) Cost Implications of Integrated CareThe potential cost-saving benefits of integrated care through efficient coordination.(00:05:34) COVID-19's Impact on Healthcare IntegrationThe pandemic's dual role in exposing challenges and providing opportunities for integrated care.(00:07:45) The Role of AI in Healthcare's FutureAI's potential in healthcare and the importance of user collaboration.(00:09:38) Importance of Iterative DevelopmentThe need for continuous collaboration in healthcare technology development.(00:12:16) Patient Perspectives in Tech DevelopmentThe value of integrating patient feedback into healthcare technology.(00:13:20) Consumer Suggestions for Health CareHow patient feedback has influenced health care improvements.(00:16:49) Iterative Development of Health Care TechnologiesThe iterative process of developing health care technologies with continuous input from end users.(00:24:29) Advice for Healthcare TechnologistsAdvice for technologists on developing useful and accepted healthcare tools.(00:27:22) Conclusion Connect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads or Twitter/XConnect with School of Engineering >>> Twitter/X

From Our Neurons to Yours
How VR could help treat depression with "radical behaviorist" Dr. Kim Bullock

From Our Neurons to Yours

Play Episode Listen Later Jul 18, 2024 21:36 Transcription Available


Today, we're going to talk about virtual reality and how it could be used to treat depression. We're talking with psychiatrist Kim Bullock, the founding director of Stanford's Neurobehavioral Clinic and Virtual Reality & Immersive Technologies (VRIT) program. Dr. Bullock — a physician certified in Neuropsychiatry, Psychiatry, and Lifestyle Medicine — calls herself a "radical behaviorist." Like other practitioners of cognitive behavioral therapy (CBT), she sees the troublesome thoughts and emotional states of many psychiatric disorders as just another form of behavior, which can be reshaped through self awareness and practice — much like you might work at avoiding junk food or not biting your nails.Of course, one of the biggest challenges is the practice part. It's no easy task for patients to practice experiencing the world in a more positive, healthy way. This is why Bullock is eager for practitioners of CBT and related forms of psychotherapy to embrace virtual reality technologies — which enable psychiatrists to prescribe precisely calibrated "experiences" to treat cognitive & behavioral disorders.We started by discussing early results from a clinical trial for a virtual reality-enhanced intervention major depressive disorder, which Dr. Bullock recently launched with support from the Wu Tsai Neurosciences Institute Neuroscience:Translate program. Join us to learn more about how VR is transforming the world of psychotherapy!Learn MoreImagining virtual reality as a simple tool to treat depression  (Stanford Medicine, 2024)Extended Reality(XR) enhanced behavioral activation for treatment of Major Depressive Disorder (2022 Neuroscience:Translate grant)Clinical Trial: Virtual Reality Behavioral Activation: An Intervention for Major Depressive DisorderThe Stanford Virtual Reality and Immersive Technologies (VR-IT) ProgramRecent VR-IT publicationsEpisode CreditsThis episode was produced by Michael Osborne, with production assistance by Morgan Honaker, and hosted by Nicholas Weiler. Art by Aimee Garza.Send us a text!Thanks for listening! If you're enjoying our show, please take a moment to give us a review on your podcast app of choice and share this episode with your friends. That's how we grow as a show and bring the stories of the frontiers of neuroscience to a wider audience. Learn more about the Wu Tsai Neurosciences Institute at Stanford and follow us on Twitter, Facebook, and LinkedIn.

Power On Your Plate
Episode 111: Transforming ME/CFS Care

Power On Your Plate

Play Episode Listen Later Jul 16, 2024 52:51


Discover the secret to removing poisons with my Detox Decoded Masterclass! https://hayliepomroy.com/detox   In this episode, I'm joined by Jaime Seltzer, Director of Scientific and Medical Outreach at the MEAction Network, to discuss the challenges faced by patients with ME/CFS and Long COVID and how it can be improved. We explain how crucial patient-reported symptoms are for accurately diagnosing ME/CFS. We also talk about Jaime's organization, the MEAction Network, and its efforts to transform clinical care and education. We also tackle the complexities of post-viral conditions and the relationship between viral damage, immune responses, and genetic factors, and explore how symptoms vary in these conditions.    Tune in to this week's episode of Fast Metabolism Matters: Transforming ME/CFS Care.   Enjoy this episode? Subscribe to Power On Your Plate on Apple Podcasts and leave a 5-star review. https://podcasts.apple.com/us/podcast/power-on-your-plate-with-haylie-pomroy/id1548802705      Sign up for the 10-Day Cleanse Challenge here! https://hayliepomroy.com/cleanse    Get a FREE hard copy of the Fast Metabolism Diet book! https://hayliepomroy.com/freebook   Become a certified Fast Metabolism Health Coach NOW! https://hayliepomroy.com/fmdc   Become a member, FREE for 30 days! https://hayliepomroy.com/member   Jaime Seltzer is the Director of Scientific and Medical Outreach at ME Action, a nonprofit advocating for those with chronic illnesses. She bridges communication between healthcare, government, and research sectors, representing ME Action globally. Additionally, Jaime collaborates with institutions like Stanford Medicine and Mayo Clinic Rochester on post-infectious chronic diseases research. She brings personal insight to her work as someone living with ME/CFS.   LinkedIn: https://www.linkedin.com/in/jaime-seltzer-b23abb14/ Twitter: https://twitter.com/exceedhergrasp1   Follow the MeAction Network. Website: https://www.meaction.net/ Instagram: https://www.instagram.com/meactnet/ YouTube: https://www.youtube.com/c/MEActionNet X: https://x.com/meactnet Facebook: https://www.facebook.com/MEActNet LinkedIn: https://www.linkedin.com/company/-meaction-the-myalgic-encephalomyelitis-action-network-/ TikTok: https://www.tiktok.com/@meactnet   #MECFS #myalgicencephalomyelitis #chronicfatiguesyndrome #chronicfatigue #chronicillness #longCOVID #postCOVIDsyndrome #diagnosis #POTS #posturalorthostatictachycardiasyndrome #SARS #MERS #PEM  

Fast Metabolism Matters with Haylie Pomroy
Episode 111: Transforming ME/CFS Care

Fast Metabolism Matters with Haylie Pomroy

Play Episode Listen Later Jul 16, 2024 52:51


Discover the secret to removing poisons with my Detox Decoded Masterclass! https://hayliepomroy.com/detox   In this episode, I'm joined by Jaime Seltzer, Director of Scientific and Medical Outreach at the MEAction Network, to discuss the challenges faced by patients with ME/CFS and Long COVID and how it can be improved. We explain how crucial patient-reported symptoms are for accurately diagnosing ME/CFS. We also talk about Jaime's organization, the MEAction Network, and its efforts to transform clinical care and education. We also tackle the complexities of post-viral conditions and the relationship between viral damage, immune responses, and genetic factors, and explore how symptoms vary in these conditions.    Tune in to this week's episode of Fast Metabolism Matters: Transforming ME/CFS Care.   Enjoy this episode? Subscribe to Power On Your Plate on Apple Podcasts and leave a 5-star review. https://podcasts.apple.com/us/podcast/power-on-your-plate-with-haylie-pomroy/id1548802705      Sign up for the 10-Day Cleanse Challenge here! https://hayliepomroy.com/cleanse    Get a FREE hard copy of the Fast Metabolism Diet book! https://hayliepomroy.com/freebook   Become a certified Fast Metabolism Health Coach NOW! https://hayliepomroy.com/fmdc   Become a member, FREE for 30 days! https://hayliepomroy.com/member   Jaime Seltzer is the Director of Scientific and Medical Outreach at ME Action, a nonprofit advocating for those with chronic illnesses. She bridges communication between healthcare, government, and research sectors, representing ME Action globally. Additionally, Jaime collaborates with institutions like Stanford Medicine and Mayo Clinic Rochester on post-infectious chronic diseases research. She brings personal insight to her work as someone living with ME/CFS.   LinkedIn: https://www.linkedin.com/in/jaime-seltzer-b23abb14/ Twitter: https://twitter.com/exceedhergrasp1   Follow the MeAction Network. Website: https://www.meaction.net/ Instagram: https://www.instagram.com/meactnet/ YouTube: https://www.youtube.com/c/MEActionNet X: https://x.com/meactnet Facebook: https://www.facebook.com/MEActNet LinkedIn: https://www.linkedin.com/company/-meaction-the-myalgic-encephalomyelitis-action-network-/ TikTok: https://www.tiktok.com/@meactnet   #MECFS #myalgicencephalomyelitis #chronicfatiguesyndrome #chronicfatigue #chronicillness #longCOVID #postCOVIDsyndrome #diagnosis #POTS #posturalorthostatictachycardiasyndrome #SARS #MERS #PEM  

Stanford Medcast
Episode 87: Minority Communities & Health Risks - Mental Health in the Hispanic and Latino Communities

Stanford Medcast

Play Episode Listen Later Jun 25, 2024 30:46 Transcription Available


In this episode, we speak with Drs. Nataly Beck, MD and Axel Valle, PsyD, founders and directors of La Clínica Latina at Stanford Medicine, who specialize in culturally sensitive care for the Hispanic and Latino communities. Both Dr. Beck and Dr. Valle are Clinical Assistant Professors in the Department of Psychiatry and Behavioral Sciences. We will discuss the significant need for Spanish-speaking care providers, considering the substantial percentage of Latinos in the U.S. We will also explore the use and meaning of “Latino” and “Hispanic,” cultural differences in this patient group, and disparities in treatment access and quality of care. Additionally, our conversation includes the barriers to care and mental health stigma among Hispanic and Latino patients and how providers can develop strategies to provide culturally sensitive care to Hispanic and Latino patients. Read Transcript CME Information: https://stanford.cloud-cme.com/medcastepisode87 Claim CE and MOC: https://stanford.cloud-cme.com/Form.aspx?FormID=1949

Noticentro
Lluvias dejan socavones y deslaves al paso del Tren Maya

Noticentro

Play Episode Listen Later Jun 24, 2024 1:51


Por las lluvias en la CDMX cae parte de los plafones en la plaza comercial Parque Lindavista Tras  una fiesta de 15 años, 7 personas fallecieron al inhalar monóxido de carbono mientras dormían en TamaulipasInvestigadores de Stanford Medicine identificaron seis subtipos de depresión y ansiedadMás información en nuestro podcast

From Our Neurons to Yours
How a new kind of brain plasticity could help make sense of addiction | Michelle Monje and Rob Malenka

From Our Neurons to Yours

Play Episode Listen Later Jun 20, 2024 22:54 Transcription Available


This week, we're diving into recent research that sheds light on a new form of brain plasticity involving changes in the insulation of nerve fibers — called myelin.  It turns out that myelin plasticity is implicated in a number of serious conditions, from epilepsy to drug abuse and addiction.We're excited to bring back two previous guests on the show to share their insights on this previously unknown form of plasticity:  Stanford psychiatry professor Rob Malenka (S1 E1 - Psychedelics and Empathy),  a pioneer in the study of synaptic plasticity and addiction, and neuro-oncologist Michelle Monje (S1 E12 - Brain Fog), who made some of the very first observations of myelin plasticity in the brain, essentially founding this field.Together, they discuss their recent findings on the role of myelin plasticity in opioid addiction and its implications for understanding addictive behaviors.Get ready to nerd out as we uncover a new angle on our brain's remarkable capacity for change.Learn MoreMyelination in the brain may be key to ‘learning' opioid addiction | Stanford Medicine (2024)Adaptive and maladaptive myelination in health and disease | Nature Reviews Neurology (2022)Brain plasticity promotes worsening of epileptic seizures, study finds | Stanford Medicine (2022)The Brain Learns in Unexpected Ways | Scientific American (2020)Brain boosting: It's not just grey matter that matters | New Scientist (2015)Neural activity promotes brain plasticity through myelin growth, researchers find | News Center | Stanford Medicine (2014)Episode CreditsThis episode was produced by Michael Osborne, with production assistance by Morgan Honaker, and hosted by Nicholas Weiler. Art by Aimee Garza.Send us a text!Thanks for listening! If you're enjoying our show, please take a moment to give us a review on your podcast app of choice and share this episode with your friends. That's how we grow as a show and bring the stories of the frontiers of neuroscience to a wider audience. Learn more about the Wu Tsai Neurosciences Institute at Stanford and follow us on Twitter, Facebook, and LinkedIn.

From Bench to Fireside
From the Origins of Immunotherapy to Curing Pediatric Cancers with Crystal Mackall, MD

From Bench to Fireside

Play Episode Listen Later Jun 13, 2024 32:56


In this episode, pioneering researcher Crystal Mackall, MD, Director for the PICI Center at Stanford Medicine, talks through what led to her contributions to cancer immunotherapy, including her point of view on tackling challenging problems like pediatric cancers. Dr. Mackall has dedicated her career to harnessing the immune system to treat cancer and was among a notable handful that helped conduct some of the first cancer immunotherapy clinical trials in the early 90s. She and PICI CSO John Connolly, PhD, explore what engineered “serial killer” T cells have to do with future treatments, the challenges of toxicity and partnering with the FDA to gain confidence in academia, all while getting into the crucial role that mentorship plays in fostering the next generation of scientific innovators.Get ready to go from bench to fireside with an eye-opening look at the past, present and future of cancer immunotherapy, as informed by Dr. Mackall's cutting-edge scientific experiences.++From Bench to Fireside™ is a new podcast from the Parker Institute for Cancer Immunotherapy (PICI) that takes you from behind the lab bench to the frontiers of cancer research. Each episode features an interview with members of the PICI Network, pioneers in cancer immunotherapy and leaders at world-renowned cancer research institutions. Throughout the conversations, these experts weigh in on the potential of the human immune system to target and eradicate cancer cells, from the latest breakthroughs in immuno-oncology to their impact on patients. Along the way, they unpack the hurdles encountered and the opportunities that lie ahead.Tune in to hear from scientific leaders who stand at the forefront of developing breakthrough immune therapies with the goal of turning all cancers into curable diseases. From Bench to Fireside™ is produced by the Parker Institute for Cancer Immunotherapy. Follow PICI on ⁠LinkedIn⁠, X ⁠@parkerici⁠ or visit ⁠www.parkerici.org⁠.

Audible Bleeding
Meet the SVS Vice President Candidates

Audible Bleeding

Play Episode Listen Later Jun 10, 2024 55:38


In this episode, Sasank Kalipatnapu (@ksasank), John Culhane and Leana Dogbe (@ldogbe4) sit down along with Dr. Dalman (@RLDalmanMD) as chair of the SVS Nominating Committee for this year, along with the two vice presidential candidates Dr. Harris and Dr Shaw to learn more about them as part of the ongoing election process.    Show links: SVS 2024 Meet the VP Candidates—Home Page—provides a comprehensive overview of all the candidates. Their professional biographies and answers to questions about their plans for the future are available in both text and video formats.   Show Guests: Dr. Linda Harris, Professor of Surgery at Jacobs School of Medicine and Biomedical Sciences, University of Buffalo, NY Dr. Palma Shaw, Professor of Surgery at State University of New York, Syracuse, NY Dr. Ronald L. Dalman, Elsa R. and Walter C. Chidester Professor and Division Chief Emeritus of Vascular Surgery at Stanford University, CA, Associate Dean for Market Development and Outreach for Stanford Medicine and Vice Chair for Clinical Affairs in the Department of Surgery    Follow us @audiblebleeding Learn more about us at https://www.audiblebleeding.com/about-1/ and provide us with your feedback with our listener survey.

From Our Neurons to Yours
Neuroscience and AI: What artificial intelligence teaches us about the brain (and vice versa) | Surya Ganguli

From Our Neurons to Yours

Play Episode Listen Later May 23, 2024 27:38 Transcription Available


The powerful new generation of AI tools that has come out over the past few years —  DALL-E, ChatGPT, Claude, Gemini, and the rest — have blown away our old ideas about what AI can do and raised questions about what it means for computers to start acting... intelligent?This week, we ask what the rise of these systems might teach us about our own biological intelligence — and vice versa. What does modern neuroscience have to say about how AI could become as flexible, efficient, and resilient as the human brain. Few people are better positioned to speak to the intersection of neuroscience and AI than today's guest: Surya Ganguli. Ganguli's lab produced some of the first diffusion models — which are at the foundation of today's AI revolution — and is now working to understand how complex emergent properties arise from biological and artificial neural networks. Ganguli is a member of the Neuroscience Theory Center at the Wu Tsai Neurosciences Institute, a Senior Fellow at Stanford's Institute for Human-Centered Artificial Intelligence (HAI), and an associate professor in Stanford's Department of Applied Physics. Further ReadingInterpreting the retinal neural code for natural scenes: From computations to neurons (Neuron, 2023)Beyond neural scaling laws: beating power law scaling via data pruning (arXiv, 2023)Cortical layer-specific critical dynamics triggering perception (Science, 2019)Stanford team stimulates neurons to induce particular perceptions in mice's minds (Stanford Medicine, 2019)What DALL-E reveals about human creativity (Wu Tsai Neurosciences Institute, 2023)Visit us!Want to learn more about AI and Neuroscience? Join us at Wu Tsai Neuro's annual symposium on October 17, 2024, which will showcase the frontiers of biological and artificial intelligence research. (More details coming soon!)Episode creditsThis episode was produced by Michael Osborne at 14th Street Studios, with production assistance by Morgan Honaker. Our logo is by Aimee Garza. The show is hosted by Nicholas Weiler at Stanford's Wu Tsai Neurosciences Institute. Send us a text!Thanks for listening! If you're enjoying our show, please take a moment to give us a review on your podcast app of choice and share this episode with your friends. That's how we grow as a show and bring the stories of the frontiers of neuroscience to a wider audience. Learn more about the Wu Tsai Neurosciences Institute at Stanford and follow us on Twitter, Facebook, and LinkedIn.

The Ricochet Audio Network Superfeed
Madison's Notes: The Contagion of Covid Policy: Dr. Jay Bhattacharya on Freedom of Speech

The Ricochet Audio Network Superfeed

Play Episode Listen Later May 3, 2024


After a storied career as a health policy expert, Stanford Medicine’s Dr. Jay Bhattacharya’s work became a political focal point during the COVID-19 pandemic, when he advocated against widespread lockdowns. He co-authored the Great Barrington Declaration, an open letter signed by infectious disease epidemiologists and public health scientists which advocated for a focused protection approach to […]

Madison's Notes
The Contagion of Covid Policy: Dr. Jay Bhattacharya on Freedom of Speech

Madison's Notes

Play Episode Listen Later May 3, 2024 55:23


After a storied career as a health policy expert, Stanford Medicine's Dr. Jay Bhattacharya's work became a political focal point during the COVID-19 pandemic, when he advocated against widespread lockdowns. He co-authored the Great Barrington Declaration, an open letter signed by infectious disease epidemiologists and public health scientists which advocated for a focused protection approach to COVID-19, and the Twitter Files revealed that his Twitter account had been placed on Twitter's "black list." In this conversation, he sits down to discuss how the history of American infectious disease affected our COVID response, the mimetic nature of lockdown policy, the importance of freedom of speech to the scientific endeavor, and more. Dr. Jay Bhattacharya is a Professor of Medicine at Stanford University. He is also a research associate at the National Bureau of Economics Research, a senior fellow at the Stanford Institute for Economic Policy Research, a senior fellow at the Stanford Freeman Spogli Institute, and the Director of the Stanford Center on the Demography of Health and Aging. He holds an MD and a PhD in Economics, both from Stanford University. Contributions to and/or sponsorship of any event does not constitute departmental or institutional endorsement of the specific program, speakers or views presented. Annika Nordquist is the Communications Coordinator of Princeton University's James Madison Program in American Ideals and Institutions and host of the Program's podcast, Madison's Notes.

New Books Network
The Contagion of Covid Policy: Dr. Jay Bhattacharya on Freedom of Speech

New Books Network

Play Episode Listen Later May 3, 2024 55:23


After a storied career as a health policy expert, Stanford Medicine's Dr. Jay Bhattacharya's work became a political focal point during the COVID-19 pandemic, when he advocated against widespread lockdowns. He co-authored the Great Barrington Declaration, an open letter signed by infectious disease epidemiologists and public health scientists which advocated for a focused protection approach to COVID-19, and the Twitter Files revealed that his Twitter account had been placed on Twitter's "black list." In this conversation, he sits down to discuss how the history of American infectious disease affected our COVID response, the mimetic nature of lockdown policy, the importance of freedom of speech to the scientific endeavor, and more. Dr. Jay Bhattacharya is a Professor of Medicine at Stanford University. He is also a research associate at the National Bureau of Economics Research, a senior fellow at the Stanford Institute for Economic Policy Research, a senior fellow at the Stanford Freeman Spogli Institute, and the Director of the Stanford Center on the Demography of Health and Aging. He holds an MD and a PhD in Economics, both from Stanford University. Contributions to and/or sponsorship of any event does not constitute departmental or institutional endorsement of the specific program, speakers or views presented. Annika Nordquist is the Communications Coordinator of Princeton University's James Madison Program in American Ideals and Institutions and host of the Program's podcast, Madison's Notes. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/new-books-network

From Our Neurons to Yours
Psychedelics, placebo, and anesthetic dreams | Boris Heifets (part 1)

From Our Neurons to Yours

Play Episode Listen Later May 2, 2024 30:27 Transcription Available


Psychedelics are a hot topic in psychiatry today.  They're producing dramatic reversals for patients with severe depression, PTSD, and other mental health conditions. But scientists still have fundamental questions about why these drugs are so effective. For example, is the "trip" even necessary? Some think it is not and are working to design drugs with similar brain chemistry but no psychoactive effects — “Taking the trip out of the drug.” Others suspect that many of the benefits of psychedelics can be attributed to hype and expectation: People expect to get better, so they do. Normally scientists control for placebo using a blinded study where patients don't know if they're getting the real treatment or a sugar pill. But how are you going to do this with mind-altering substances? Patients are probably going to figure out pretty quickly whether they got a sugar cube with or without LSD. Today's guest, Stanford anesthesiologist Boris Heifets, has come up with a particularly clever strategy to tease apart the psychedelic experience, biochemistry, hype and placebo. Listen for the whole story!Learn more:The Heifets Lab at Stanford MedicineDepression, ketamine & anesthesia:Randomized trial of ketamine masked by surgical anesthesia in patients with depression (Nature 2023 - paywall)Ketamine's effect on depression may hinge on hope (Stanford Medicine, 2023)Anesthetic dreams and trauma recovery:Case report 1: dreaming & knife attack (A & A Practice, 2022 - paywall)Case report 2: dreaming & PTSD (American Journal of Psychiatry, 2024)Could anesthesia-induced dreams wipe away trauma? (Stanford Medicine, 2024)Video: Mothers with PTSD following their sons' deaths talk about dreaming of their sons under anesthesia (Heifets Lab, 2024 — content advisory)Related episodes:S1 E1: Psychedelics and EmpathyS3 E3: OCD and KetamineEpisode creditsThis episode was produced by Michael Osborne at 14th Street Studios, with production assistance by Morgan Honaker. Our logo is by Aimee Garza. The show is hosted by Nicholas Weiler at Stanford's Wu Tsai Neurosciences Institute. Thanks for listening! If you're enjoying our show, please take a moment to give us a review on your podcast app of choice and share this episode with your friends. That's how we grow as a show and bring the stories of the frontiers of neuroscience to a wider audience. Learn more about the Wu Tsai Neurosciences Institute at Stanford and follow us on Twitter, Facebook, and LinkedIn.

Hope and Help For Fatigue & Chronic Illness
EP20: ME/CFS in Action: Transforming Chronic Illness Care

Hope and Help For Fatigue & Chronic Illness

Play Episode Listen Later May 1, 2024 50:55


Watch Jaime Seltzer and other experts share their expertise at the INIM Conference 2024 on May 10, 2024. Register here: https://www.nova.edu/nim/events.html   In this episode, Haylie Pomroy and Jaime Seltzer discuss the challenges faced by patients with myalgic encephalomyelitis (ME/CFS) and Post-COVID Syndrome (or Long COVID) in obtaining proper diagnosis and treatment due to the lack of understanding among medical providers.  Together, they emphasize the importance of patient-reported symptoms in diagnosing ME/CFS accurately and discuss efforts by Jaime's organization, ME Action, to improve clinical care and education. Don't miss out on this episode as Jaime and Haylie explain the complexities of post-viral conditions like ME/CFS and Long Covid, including the relationship between viral damage, immune responses, and genetic factors. Explore the various sources of symptoms in these conditions and the need for personalized approaches to address them effectively.   Resources Mentioned: Mayo Clinic Paper, “Diagnosis and Management of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome”: https://www.mayoclinicproceedings.org/action/showPdf?pii=S0025-6196%2823%2900402-0   Pacing and Management Guides: https://www.meaction.net/resource/pacing-and-management-guide/   Neuroinflammation Research Review (2019) by Jaime Seltzer: http://www.meaction.net/wp-content/uploads/2019/06/19_MEA_Revised_2019_Research_Summary_190610.pdf   Subscribe to the MEAction Newsletter: https://www.meaction.net/subscribe/   Donate to the MEAction Network: meaction.net/donate   Jaime Seltzer is the Director of Scientific and Medical Outreach at ME Action, a nonprofit advocating for those with chronic illnesses. She bridges communication between healthcare, government, and research sectors, representing ME Action globally. Additionally, Jaime collaborates with institutions like Stanford Medicine and Mayo Clinic Rochester on post-infectious chronic diseases research. She brings personal insight to her work as someone living with ME/CFS. LinkedIn: https://www.linkedin.com/in/jaime-seltzer-b23abb14/ Twitter: https://twitter.com/exceedhergrasp1 Website: https://www.meaction.net/ —------------------------------------------------------------------------------------------------ Thank you for tuning in to the Hope and Help For Fatigue and Chronic Illness Podcast. Sign up today for our newsletter.

The Development Debrief
145. Deb Lin: CFR 101

The Development Debrief

Play Episode Listen Later Apr 1, 2024 33:53


This week, Deb shares her perspective as a corporate and foundation relations professional. In the second episode on this topic, we compare it to individual giving and learn more about how the space is unique. Deborah Lin is the Director of Corporate, Foundation, & Association Relations at Stanford Medicine, leading the team closing and facilitating organizational philanthropic support to the School of Medicine and Stanford Healthcare. She has built over a decade of experience in academic research fundraising and programmatic strategy and operations. Before Stanford University, Deborah was the Associate Director of Corporate Relations at UCLA Engineering, spearheading engagement and partnerships for the school with industries such as tech, aerospace, and energy. She was a founding team member of Partnership UCLA, a department that engages alumni in helping student career development, creating and launching campus-wide programs supporting thousands of students' professional and academic development. In addition to academia, she has also worked in the media and tech industries. Before UCLA, Deborah worked in the Television and Film industry for companies such as Disney ABC Studios and 20th Century Fox, managing global marketing partnerships, production, talent management, and television comedy development. --- Support this podcast: https://podcasters.spotify.com/pod/show/devdebrief/support

The Tim Ferriss Show
#708: Dr. Andrew Huberman — A Neurobiologist on Optimizing Sleep, Enhancing Performance, Reducing Anxiety, Increasing Testosterone, and Using the Body to Control the Mind (Repost)

The Tim Ferriss Show

Play Episode Listen Later Dec 5, 2023 161:26 Very Popular


Brought to you by AG1 all-in-one nutritional supplement, Momentous high-quality supplements, and Eight Sleep's Pod Cover sleeping solution for dynamic cooling and heating.Andrew Huberman, PhD (@hubermanlab), is a neuroscientist and tenured professor in the Department of Neurobiology at Stanford University's School of Medicine. He has made numerous important contributions to the fields of brain development, brain function, and neural plasticity. Work from the Huberman Laboratory at Stanford Medicine has been consistently published in top journals including Nature, Science, and Cell.Andrew is the host of the podcast Huberman Lab, which is often ranked as one of the top five podcasts in the world by both Apple and Spotify. The show aims to help viewers and listeners improve their health with science and science-based tools. New episodes air every Monday on YouTube and all podcast platforms.Please enjoy!This episode was originally published in July, 2021. Show notes and resources from this episode: https://tim.blog/2021/07/06/andrew-huberman/*This episode is brought to you by AG1! I get asked all the time, “If you could use only one supplement, what would it be?” My answer is usually AG1, my all-in-one nutritional insurance. I recommended it in The 4-Hour Body in 2010 and did not get paid to do so. I do my best with nutrient-dense meals, of course, but AG1 further covers my bases with vitamins, minerals, and whole-food-sourced micronutrients that support gut health and the immune system. Right now, you'll get a 1-year supply of Vitamin D free with your first subscription purchase—a vital nutrient for a strong immune system and strong bones. Visit DrinkAG1.com/Tim to claim this special offer today and receive your 1-year supply of Vitamin D (and 5 free AG1 travel packs) with your first subscription purchase! That's up to a one-year supply of Vitamin D as added value when you try their delicious and comprehensive daily, foundational nutrition supplement that supports whole-body health.*This episode is also brought to you by Momentous high-quality supplements! Momentous offers high-quality supplements and products across a broad spectrum of categories, and I've been testing their products for months now. I've been using their magnesium threonate, apigenin, and L-theanine daily, all of which have helped me improve the onset, quality, and duration of my sleep. I've also been using Momentous creatine, and while it certainly helps physical performance, including poundage or wattage in sports, I use it primarily for mental performance (short-term memory, etc.).Their products are third-party tested (Informed-Sport and/or NSF certified), so you can trust that what is on the label is in the bottle and nothing else. If you want to try Momentous for yourself, you can use code Tim for 20% off at LiveMomentous.com/Tim. And not to worry, my non-US friends, Momentous ships internationally and has you covered. *This episode is also brought to you by Eight Sleep! Eight Sleep's Pod Cover is the easiest and fastest way to sleep at the perfect temperature. It pairs dynamic cooling and heating with biometric tracking to offer the most advanced (and user-friendly) solution on the market. Simply add the Pod Cover to your current mattress and start sleeping as cool as 55°F or as hot as 110°F. It also splits your bed in half, so your partner can choose a totally different temperature.Conquer this winter season with the best in sleep tech and sleep at your perfect temperature. Many of my listeners in colder areas enjoy warming up their bed after a freezing day. Go to eightsleep.com/tim and save $250 on the Pod Cover by Eight Sleep this winter. Eight Sleep currently ships within the USA, Canada, the UK, select countries in the EU, and Australia. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.