Podcasts about zoster

This week Kate, Gary, Mark and Henry discuss discontinuation of benzodiazepines and treatment of insomnia, the value of baseline cognitive testing of college athletes, vonoprazan vs PPI for preventing and treating ulcers, and whether herpes zoster vaccine reduces dementia risk.Show links:Essential Evidence Plus: www.essentialevidenceplus.comTapering benzos: https://pubmed.ncbi.nlm.nih.gov/39374004/ Baseline neuro eval for athletes: pubmed.ncbi.nlm.nih.gov/39741470/ David Kaufman, “We Need You in the Locker Room” https://thesagergroup.net/books/in-the-locker-room Vonoprazan vs PPIs for ulcers: https://pubmed.ncbi.nlm.nih.gov/39294424/ Zoster and dementia: https://pubmed.ncbi.nlm.nih.gov/40175543/ 

On episode #76 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 2/27/25 – 3/12/25. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Trends in respiratory pathogen testing at us children's hospitals (JAMA Network) Changes in respiratory viral testing before and after the covid-19 pandemic(JAMA Network) Expanding measles outbreak in the United States and guidance for the upcoming travel season (CDC Emergerncy Preparedness and Response) Measles cases and outbreaks (CDC Measles (Rubeola)) Facts and myths about measles (LANCET: Infectious Diseases) Protective effects of recombinant zoster vaccine and antiviral therapy against cardiovascular disease following herpes zoster infection (JID) Chikungunya vaccine information for healthcare providers (CDC Chikungunya Virus) Factors to assess when considering use of chikungunya vaccine(CDC) Bacterial Should patients hospitalized forcommunity-acquired pneumonia be treated with additional antimicrobial agents directed against anaerobes? (American Journal of Therapeutics) Antibiotic-induced loss of gut microbiome metabolic output correlates with clinical responses to CAR T-cell therapy(Blood) Effectiveness of ampicillin/sulbactam versus ceftriaxone for the initial treatment of community-acquired pneumonia in older adults: a target trial emulation study(OFID) Male-partner treatment to prevent recurrence of bacterial vaginosis(NEJM) Fungal The Last of US Season 2 (YouTube) Activity of rezafungin against echinocandin non–wild type candida glabrata clinical isolates from a global surveillance program (OFID) Are contemporary antifungal doses sufficient for critically ill patients? Outcomes from an international, multicenter pharmacokinetics study for Screening Antifungal Exposure in Intensive Care Units—the SAFE-ICU study  (Intensive Care Medicine) Parasitic Human alveolar echinococcosis – global, regional and national annual incidence and prevalence rates (CMI: Clinical Microbiology and Infection) Dust to Diagnosis – with MSGERC (FEBRILE) The clinical picture caused by Fasciola gigantica: Analysis of 3,250 patients along the 1995–2019 countrywide spread in Vietnam (OFID) Miscellaneous Reprint of: From medical editors: a call to the global infectious diseases and clinical microbiology community (CMI: Clinical Microbiology and Infection) A hot topic: A climate-focused track for infectious disease fellowship (OFID) Are we being gaslit? A primer for recognizing corporate jargon to overcome gaslighting for the infectious disease workforce (CID) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.

“Only fear the Lord and serve him faithfully with all your heart. For consider what great things he has done for you.” 1 Sam 12:24. The Knoxville Academy of Medicine Alliance's Doc Rock for Health is SAT, JAN 18th at The Mill & Mine.  Part of the proceeds go to these wonderful charity organizations serving our East Tennessee neighbors!  With me is Beth Roskelly, Director of Development & Public Relations - InterFaith Health Center, Adelyn Pair - Associate Director of Marketing & Communications of Emerald Youth Foundation, Martin Vargas - Exec Director of St. Mary's Mobile Health Clinic, and Holly Kizer - Assistant Development Coordinator joins us from Thrive/ Soar Youth Ministries. Dr. Lytle Brown who returns as our Emcee and Kirstin Kropilak, Co-Chair of Doc Rock are here!  Our community changes one person at a time through the love and concern these people give others! Our bands - No Recall, B.B.S, Dr. Zoster & the Pox, and Remedy, are back! Thanks to Ministry Partners Campbell Dental Care & Denise King, Realtor - Noble Realty. Crossroads With Jenny Bushkell 5pm - 6pm. Joy620 WRJZ! 620 AM, 102.5 99.5 FM Sevier, streaming at wrjz.com or download our JOY620 App! The Mill & Mine SAT, JAN 18th, 2025. Doors open at 6:00pm! Music 7:00pm! Come and enjoy!! All for a great cause - serving our neighbors with health-care and love! Friday on @Crossroads withJenny we will hear how all these organizations are serving our East Tennessee neighbors. 

Dr. Patrick Danaher, Infectious Diseases Clinician at the USF Morsani College of Medicine, discusses the various dermatologic manifestations of HIV in this recorded session. Among the topics discussed includes genital herpes disease, Zoster, Mpox infections, MRSA skin lesions, and Kaposi sarcoma. The lecture is presented in a case-based format.

We are introducing you to summer edition of show Incubator of Good Music with songs from the best-selling albums in the half-yearly list and offering the HR Top 40 chart changes. Host: Ana Radišić

GOLD 2024 KOAH Kılavuzu Güncellemesi Türkçe özetine devam ediyoruz. Önceki bölümlerde kılavuzun birinci ve ikinci bölümlerini özetlemiştik. Bu bölümde ise kılavuzun 3. bölümünü (KOAH'ın Önlenmesi ve Yönetimi) ana hatlarıyla özetlemeye çalışacağız. GİRİŞ KOAH yönetimindeki genel amaç; semptomları, alevlenmeyi ve riskleri azaltmaktır. Stabil KOAH tedavisindeki amaçlar içinde; semptomları tedavi etmek, egzersiz toleransını arttırmak, sağlık durumunu geliştirmek, hastalık gidişatı önlemek, alevlenmeleri önlemek ve tedavi etmek ve mortaliteyi azaltmak yer alır. KOAH hastalarında tedaviyi yönlendirmek amacıyla havayolu obstrüksiyonunun ciddiyeti, semptomlar, alevlenme geçmişi, risk faktörlerine maruz kalma ve komorbiditeler değerlendirilmelidir. Bu bölüm KOAH'lı hastaların yönetiminden ve önleme stratejilerinden bahsedeceğiz. Kanıt Düzeyleri Kanıt temelli önerilere yer verildiğinde, bu önerilerin kanıt düzeyleri parantez içinde şu şekilde sunulmuştur: (Kanıt A). Aşağıdaki tabloda Kanıt Düzeyleri ve anlamları yer almaktadır: Kanıt KategorisiKanıt KaynağıARandomize Kontrollü ÇalışmalarABelirgin sınırlılık veya taraflılık içermeyen yüksek kaliteli zengin kanıtlarBÖnemli sınırlılıkları olan randomize kontrollü çalışmalarBSınırlı kanıtlarCRandomize olmayan çalışmalarGözlemsel çalışmalarDPanel konsensus değerlendirmesi Risk Faktörlerini Belirleme ve Maruz Kalmayı Azaltma Risk faktörlerinin belirlenmesi ve maruziyetin azaltılması yalnızca KOAH'ın birincil önlenmesi için değil aynı zamanda yönetimin bir parçası olarak da önemlidir.  Sigara içmek en sık karşılaşılan ve kolayca tanımlanabilen bir risk faktörüdür (KOAH'lıların %40'ı sigara içmektedir), bu yüzden sigara içen tüm bireylerin sigarayı bırakması sürekli olarak teşvik edilmelidir (Kanıt A). Sigarayı bırakma, KOAH'ın doğal seyrini etkileme konusunda en büyük kapasiteye sahiptir. Günlük semptomları iyileştirir ve alevlenme sıklığını azaltır. Mesleki tozlara, dumanlara ve gazlara, ev içi veya ev dışı hava kirliliğine maruziyetin azaltılması da önemlidir. Etkin havalandırma, çevreyi kirletmeyen ocaklar ve benzeri müdaheleler önerilmelidir (Kanıt B). Klinisyenler mümkünse potansiyel tahriş edici maddelere sürekli maruz kalmaktan kaçınmaları konusunda hastalara tavsiyede bulunmalıdır (Kanıt D). Aşılanma İnfluenza aşısı, KOAH'lılarda ciddi hastalanmayı (hastane yatışı gerektiren durumlar gibi) ve ölümü azaltır. Sadece birkaç çalışma KOAH alevlenmelerinde influenza aşısını değerlendirmiş ve kişi başına düşen toplam alevlenme sayısında anlamlı azalma olduğunu göstermiştir. İnfluenza aşısı KOAH'lı hastalara önerilmektedir (Kanıt B). Pnömokok aşıları, pnömokok konjuge aşısı ( PCV20 veya PCV15) ve pnömokok polisakkarit aşısı (PPSV23) 65 yaş üzeri bireyler için onaylanmıştır. Ayrıca 19-64 yaş arasında kronik akciğer hastalığı olan, organ nakilli, sigara içen bireyler için de önerilmektedir. Aşılanma konusunda bir doz PCV15 sonrasında PPSV23 ya da sadece bir doz PCV20 önerilmektedir (Kanıt B). Pnömokok aşısı toplum kökenli pnömoni riskini ve KOAH alevlenme sıklığını azaltmaktadır (Kanıt B). Kronik kalp/akciğer hastalığı, immün yetmezlikli hastalar, bakımevi hastaları, ciddi RSV enfeksiyonu geçirme riskine sahiptir. CDC'ye göre her yıl RSV kaynaklı 60.000-160.000 hastane yatışı olmakta ve 6.000-10.000 ölüm görülmektedir. Bu yüzden RSV aşısı 60 yaş üstü kişilerde veya kronik kalp/akciğer hastalığı olan kişilerde önerilmektedir (Kanıt A). Ergenlik çağında Tdap aşısı olmayan KOAH'lılar için Tdap aşısını (Kanıt B) ve 50 yaşın üzerindeki KOAH'lı kişiler için zonaya karşı koruma için Zoster aşısını (Kanıt B) önermektedir. COVİD-19 aşısı tüm KOAH'llı hastalar için önerilmektedir (Kanıt B). Stabil KOAH'ta Farmakolojik Tedavi  Semptomların ve alevlenme sıklığının ciddiyetine göre tedavi planı belirlenir. Tedavi semptomlara göre arttırılabilir veya azaltılabilir. Başlangıçtaki farmakoterapi hastanın hangi GOLD grubunda olduğuyla başlar:

Sono tanti, tantissimi e abbiamo l'impressione che ce l'abbiano con noi specie in questo periodo. A Obiettivo Salute Weekend parliamo di virus. Sono piccolissimi, non li vediamo, ma sappiamo che possono avere un impatto significativo sulla nostra salute e per questo ci fanno paura. Ma tutto dipende da chi si incontra. Non sono tutti cattivi allo stesso modo. Ne parliamo con il prof. Donato Zipeto, Professore di Biologia molecolare università di Verona.A seguire con la prof.ssa Alessandra Bandera, direttrice Malattie Infettive Policlinico di Milano, parliamo del virus della varicella che causa l’herpes. Focus su Simplex e Zoster

Bienvenidos, un espacio donde podrás preguntar por todo lo que te preocupa de salud y donde encontrarás los nutrientes necesarios para mejorar tu calidad de vida...

Saznajte više o najgorem albumu u regiji. "Najgori"- tako zapravo glasi naslov novog albuma grupe Zoster koja nakon osam godina objavljuje novi materijal. Frontman Zostera, Mostarac Mario Knezović, u razgovoru s Amirom Kamberom govori o čemu se radi. Ko je najgori među najboljima? Zbog čega je teško suditi o vlastitom radu? Scenske novosti iz Sarajeva donosi reporter Zoran Ćatić. Slušamo muzičke novitete. Zašto Mapo Keys iz Beograda ide na Planin-u dok duo Revirgin iz Čakovca pazi na Disciplinu? Von Amir Kamber.

This week, Dr. Jack Cush reviews the news with special guest, Dr. Janet Pope. They discuss "Not-non-Inferior", large scale genetic screening, Zoster risk w/ newer lupus drugs, Tapering, RA referral problems and the TNR webinar session on "Oral Surveillance Revisited"

A banda de la Grip, la Covid o el Tètanus la vacunació d’adults acaba d’afegir dues noves vacunes com són la de la Pneumònia i la de l’Herpes Zoster. Els nascuts l’any 1942, 1943, 1957 i 1958 i també els majors de 90, aquells que hagin passat dues vegades l’Herpes Zoster o persones inmunodeprimides rebran, si no l’han rebut ja, l’avís del CAP per a que s’apropin a posar-se les […] L'entrada Les vacunes de l’Herpes Zoster i la Pneumònia entren al calendari vacunacional d’adults ha aparegut primer a Radio Maricel.

In this episode of the Matter of Vax podcast, host Steph O'Connell discusses shingles and vaccines with guest Dr. Paul Van Buynder, a public health physician and professor in the School of Medicine at Griffith University. Shingles is a common and painful condition that affects a large number of Australians each year, especially those over the age of 50. Dr. Van Buynder explains the long-term consequences of shingles, including postherpetic neuralgia and eye complications He discusses two vaccines available in Australia, Zoster and Shingrix, highlighting the benefits and drawbacks of each and ways to protect oneself against shingles.  Visit Immunisation Foundation of Australia for more information Host Steph O'Connell is a public health advocate with 25 years' experience in strategic communications. She became a public voice for vaccinations when her daughter, Lily (23), narrowly survived W strain of Meningococcal on Christmas Day, 2017. Nine months later her sister, Grace, donated a kidney that has since transformed Lily's life.  Steph's advocacy for immunisation awareness and vaccination became a collaboration in 2018 with Meningococcal Australia and resulted in Meningococcal vaccination campaigns by the Australian Government Department of Health and NSW Health. Lily's story quickly resonated with audiences and became a national and international appeal for awareness, education and vaccination.  Steph's work expanded during the pandemic and today she continues to advocate for improved access to vaccines, public education for lifelong vaccination behaviour and policy reform. MatterofVax, in collaboration with Immunisation Foundation of Australia takes a look at topical immunisation issues on video and podcast.  Matter of Vax is produced by Ampel, for Immunisation Foundation of Australia. See omnystudio.com/listener for privacy information.

Winkelheide, Martinwww.deutschlandfunk.de, SprechstundeDirekter Link zur Audiodatei

Čak dva sjajna gosta danas! Članovi benda Rebel Star, Milan Glavaški i Zvonka Obajdin, lično nam predstavljaju pjesmu Mesec koja impresivno najavljuje njihov novi album. Pitamo: kako to teče saradnja muzičara na liniji Sent Andreja, Zagreb i Beograd? Kada je bolje snimati u Beogradu a kada u Zagrebu? Iz Sarajeva sa scenskim novostima iz BiH javlja se reporter Zoran Ćatić. Amir Kamber predstavlja novitete: Pocket palma iz Hrvatske, Oxajo iz Srbije i bend iz Mostara koji je pustio mozak na pašu. Von Amir Kamber.

El Centro Médico de UPP atiende semanalmente con el Doc Fernando Mozún.

Herpes Zoster Ophthalmicus (HZO) can cause multiple ocular issues, most commonly in the anterior segment. What is the role of long-term antivirals and steroids? Is the potential havoc wreaked by HZO more so related to the virus or the inflammatory cascade it initiates? How long should patients be kept on antivirals? When is it safe to administer the Shingles vaccine? Dr. Clara Chan joins the podcast.

Einen Herpes Zoster erkennt man oft auf den ersten Blick. Deutlich schwieriger gestaltet sich hingegen das Schmerzmanagement, besonders bei älteren und komorbiden Erkrankten. Der Allgemeinmediziner Prof. Dr. Jörg Schelling spricht in dieser Folge über die therapeutischen Herausforderungen bei Herpes Zoster und erklärt, warum rechtzeitiges Impfen von Risikogruppen – über und unter 60 Jahren – so wichtig ist.

Zvuk, koncert, pokret i akustika na jednoj izložbi! U tunelu. Tipično za Bojana Vuletića, kompozitora, poznatog po neobičnim kompozicijama i saradnji sa umetnicima raznih profila. Pitamo ga kako mu je uspelo da to stopi s prostorom? „The space between your ears“, zvučna izložba koju treba doživeti, od 4.-12. februara, KIT u Diseldorfu. A sa muzičke scene BiH, naš Zoran Ćatić javlja o saradnji sarajevskog hip hop sastava Helem Nejse i Amire Medunjanin i novitetima Zabranjenog Pušenja i Zostera. Von Boris Rabrenovic.

Claim CME  The CE experience for this Podcast is powered by CMEfy - click here to reflect and earn credits: https://earnc.me/tn70Yk   Dr. Rosenblum discuss a challenging case and reviews the pathology, treatment and evidence for interventional pain in the the treatment of Post Herpetic Neuralgia. Discussed in this podcast: Intrathecal injection of methylprednisolone Dorsal Root Ganglion  Paraveterbral Nerve Block Stellate Ganglion Block Spinal Cord Stimulation Botulinum Toxin Injection And more!   Course Calendar   Ultrasound Guided Regional Anesthesia and  Pain Medicine Tamarindo, Puerto Rico- Feb. 10, 2023   Ultrasound Guided Regional Anesthesia and  Pain Medicine Tamarindo, Costa Rica- Feb. 19, 2023   Ultrasound Guided Regional Anesthesia and Pain Medicine NYC- March 11, 2023   Ultrasound Guided Regional Anesthesia and Pain Medicine NYC- April 22, 2023 Regenerative Pain Medicine Course NYC- May 13   Pain Management Board Review/Refresher Course/ Ultrasound Training NYC- June 9-11, 2023   References Lin, Chia-Shiang, et al. "Interventional treatments for postherpetic neuralgia: a systematic review." Pain physician22.3 (2019): 209. https://www.painphysicianjournal.com/current/pdf?article=NjMwMg%3D%3D&journal=120

Svakog petka vodimo vas na muzičku Korzo šetnju. Gost je Ante Gelo, jedan od najtraženijih hrvatskih gitarista, aranžer i producent. „Dosta sam radio za druge i sad mi je došlo da napravim nešto za sebe, pravi gušt!“. Nakon dve decenije rada sa brojnim poznatim muzičarima nedavno objavio džez album prvenac „Mara“. Iz Zagreba stižu novosti sa muzičke scene Hrvatske od Zorana Stošića i uz to zanimljive priče o Massimu, Darku Rundeku i najopsežnijem muzičkom albumu na svetu koji stiže iz Slovenije. Von Boris Rabrenovic.

Lexman interviews UFC Welterweight Champion Ben Askren about spin-dryers, zoster, purgers, and exotic router types.

Šetamo muzičkim scenama na jugoistoku Evrope i razgovoramo sa Vanjom Mišić iz ekipe koja organizira OK Fest u Nacionalnom parku Sutjeska. Muzički festival na vrh planine. Moto: Jer smo totalno drukčiji od drugih. Odličan program. Unikatna festivalska lokacija. Fešta, druženje, kamping. Nešto kasnije idemo do Zagreba i našeg reportera Zorana Stošića po najnovije novosti s tamošnje muzičke scene. Slušamo novitete od grupe Zoster, sastav S-.A.R.S i Neli feat. Matija Dedic. Von Amir Kamber.

Adnan Šaran iz sarajevske grupe Skroz objavio pjesmu sa starijim bratom Dinom Šaranom sa kojim po prvi put sarađuje na taj način. Kako to? Nova pjesma je povezana s dokumentarnim filmom Skroz Sarajevo koji je upravo zgotovljen. Muzički reporter Zoran Ćatić donosi niz drugih novosti sa scene u Bosni i Hercegovini. Slušamo svježu muziku s jugoistoka Evrope, novi single Massima Savića. Tu su Mapo Keys iz Srbije i Natali Dizdar iz Hrvatske. Pitamo se i ko na dalekom jugu zvuči kao Frank Sinatra? Von Amir Kamber.

Herpes zoster is a public health concern for the public, especially in subjects who are immunocompromised. The CDC–recommended recombinant zoster vaccine (RZV) is an effective way to reduce the incidence of herpes zoster, but because of the increased immunogenicity of the vaccine adjuvant, there is a concern about flares of underlying autoimmune diseases in rheumatology patients. Join Drs. Syed Raza Saurav Acharya, and Gabrielle Howard, as they discuss the safety of RZV in this patient population, a topic they, and their coauthor Debendra Pattanaik, addressed in their February 2022 Southern Medical Journal article. In this podcast, they talk about why patients with rheumatic diseases are found to be at higher risk of herpes zoster and what led them to conduct their study. Additionally, they provide evidence of the safety of  RZV in subjects with rheumatologic diseases.

Word nerds rejoice! In this episode we play the alphabet game with our favorite oddball terms from fashion's history. Learn more about your ad-choices at https://www.iheartpodcastnetwork.com

Welcome to Episode 12 of “The 2 View,” the podcast for EM and urgent care nurse practitioners and physician assistants! Show links below: Ondansetron in Children: https://journalfeed.org/article-a-day/2021/isolated-vomiting-is-it-just-a-virus https://journalfeed.org/article-a-day/2021/does-ondansetron-impact-meaningful-outcome-in-preschoolers https://journalfeed.org/article-a-day/2020/maybe-ondansetron-rx-does-reduce-bouncebacks-in-ki Auricular Hematomas & Auricular Block: Martha's Video https://youtu.be/jND3_4SdQvU Martha's Blog https://www.theproceduralist.org/thecases/auricular-blocks-and-hematomas Auricular Hematoma's https://www.ncbi.nlm.nih.gov/books/NBK531499/ Jess Mason's video on auricular blocks https://www.youtube.com/watch?v=6ZiB_9eNpcA Auricular Hematoma Drainage https://www.youtube.com/watch?v=mXjQu26BlIg Langer's Lines https://dermnetnz.org/topics/skin-tension-lines Bolsters https://www.aliem.com/trick-of-trade-splinting-ear/ Latest Guidelines of Zoster / Shingles: CDC https://www.cdc.gov/shingles/index.html Merck Manual https://www.merckmanuals.com/professional/infectious-diseases/herpesviruses/herpes-zoster Facial Dermatomes https://www.ebmconsult.com/articles/anatomy-dermatomes-face AAFP - Shingles https://www.aafp.org/afp/2000/0415/p2437.html Gabapentin https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0217335 The Usual Links: CCME www.ccme.org SGEM: www.thesgem.com The Proceduralist: www.theproceduralist.org Old Procedural Pause videos: https://journals.lww.com/em-news/blog/theproceduralpause/pages/default.aspx

Cabello, R. R., Feregrino, R. R., & Feregrino, R. R. (2018). Microbiología y parasitología humana: Bases etiológicas de las enfermedades infecciosas y parasitarias. Editorial Médica Panamericana. --- Send in a voice message: https://anchor.fm/las-poderosas-celulas-nk/message

O boală obișnuită care afectează cel puțin 120 de mii de australieni în fiecare an și are ca rezultat simptome pe termen lung în aproximativ 25-30 la sută din cazuri.Cu toate acestea, multi nu cunosc încă semnele timpurii ale bolii zona zoster (shingles).

New to RheumNow? Rheumnow.com is a news source dedicated to the field of Rheumatology. It is written by experts in the field, and written for rheumatologists and individuals working in related fields. In this episode, Dr. Jack Cush reviews the news and journal articles from the past week on RheumNow.com Metanalysis of JAK inhibition (tofacitinib & ruxolitinib) in alopecia areata - 12 studies, 346 Pts, Rx success (using SALT50 resp) was 66%, not influenced by age, sex, subtype. Alopecia recurrence seen w/in 3 mos of JAK D/C (in74%) https://t.co/CBSy4Kci80 Population study shows risk of H. Zoster in adults to be high among bDMARD and CTX, also increased w/ AZA and HCQ but not MTX SSZ or LEF users. Data from 254065, 1,826311 Pt-Yrs F/U, 6295 new DMARD users, 17024 incident HZ https://t.co/1TeOAWN9LB MMWR reports that during the COVID Delta variant era, Vaccination against COVID-19: - Reduces risk of COVID-19 infection 5X - Reduces risk of COVID-19 Hospitalization ⋗10X - Reduces risk of COVID-19 DEATH 10X https://t.co/rMRY84xX5F Study of 265 students w/ a positive COVID-19 test looked at 378 close contacts. Infx rates w both persons masked -7.7%, but when unmasked-32.4% (aORs = 4.9) https://t.co/fYdH33JbWR Effect of Diet on COVID Outcomes Probenecid, an OAT3 inhibitor, has inhibitory effects on RNA viruses (influenza, RSV) & decreases ACE2 expression. May have utility in COVID-19 as it was shown to inhibit SARS-CoV-2 replication in animal modelshttps://t.co/MClSjpqpSa Mease and colleagues have catalogued the current practices assessed in the CORRONA registry, noting that increased DMARD switching and decreased time on a given therapy by US physicians. https://t.co/cIWZw6KsuI A retrospective study of systemic sclerosis patients shows that acute hospitalization and mortality were not uncommon and were often linked to SSc-related lung disease. #RheumNow https://t.co/s5wSlndTrt Cases and Questions (AKA Back Talk) “What treatment do you use after 2 years of teraparitide in a woman with a hx of OP, spiral fracture while on a bisphosphonate”? Forteo PI. “Do you have any inside info on the vaccines for COVID-19 during pregnancy?” OCOG Statement “Status of the Tocilizumab Shortage”? Genentech Statement “How would you treat polyarthritis in a renal transplant patient?” CONNECT WITH RheumNow ✩ Website - https://rheumnow.com/ ✩ Subscribe @ RheumNow: https://rheumnow.com/user/register ✩ LinkedIn - https://www.linkedin.com/in/john-cush... ✩ RheumNow LinkedIn: https://www.linkedin.com/company/rheu... ✩ Twitter - https://twitter.com/RheumNow Listen | PODCAST Apple Podcasts: https://podcasts.apple.com/us/podcast... Spotify: https://open.spotify.com/show/4Mjzj5j... Stitcher: https://www.stitcher.com/show/the-rhe... TuneIn: https://tunein.com/podcasts/Health--W... Podbean: https://rheumnow.podbean.com/ Got a Rheumatology question or case for Dr. Jack Cush? Record it here and we'll feature it on an upcoming podcast. Tell us your name and where you practice rheumatology. BackTalk: https://rheumnow.com/submit-podcast-question-or-comment

New to RheumNow? Rheumnow.com is a news source dedicated to the field of Rheumatology. It is written by experts in the field, and written for rheumatologists and individuals working in related fields. In this episode, Dr. Jack Cush reviews the news and journal articles from the past week on RheumNow.com Metanalysis of JAK inhibition (tofacitinib & ruxolitinib) in alopecia areata - 12 studies, 346 Pts, Rx success (using SALT50 resp) was 66%, not influenced by age, sex, subtype. Alopecia recurrence seen w/in 3 mos of JAK D/C (in74%) https://t.co/CBSy4Kci80 Population study shows risk of H. Zoster in adults to be high among bDMARD and CTX, also increased w/ AZA and HCQ but not MTX SSZ or LEF users. Data from 254065, 1,826311 Pt-Yrs F/U, 6295 new DMARD users, 17024 incident HZ https://t.co/1TeOAWN9LB MMWR reports that during the COVID Delta variant era, Vaccination against COVID-19: - Reduces risk of COVID-19 infection 5X - Reduces risk of COVID-19 Hospitalization ⋗10X - Reduces risk of COVID-19 DEATH 10X https://t.co/rMRY84xX5F Study of 265 students w/ a positive COVID-19 test looked at 378 close contacts. Infx rates w both persons masked -7.7%, but when unmasked-32.4% (aORs = 4.9) https://t.co/fYdH33JbWR Effect of Diet on COVID Outcomes Probenecid, an OAT3 inhibitor, has inhibitory effects on RNA viruses (influenza, RSV) & decreases ACE2 expression. May have utility in COVID-19 as it was shown to inhibit SARS-CoV-2 replication in animal modelshttps://t.co/MClSjpqpSa Mease and colleagues have catalogued the current practices assessed in the CORRONA registry, noting that increased DMARD switching and decreased time on a given therapy by US physicians. https://t.co/cIWZw6KsuI A retrospective study of systemic sclerosis patients shows that acute hospitalization and mortality were not uncommon and were often linked to SSc-related lung disease. #RheumNow https://t.co/s5wSlndTrt Cases and Questions (AKA Back Talk) “What treatment do you use after 2 years of teraparitide in a woman with a hx of OP, spiral fracture while on a bisphosphonate”? Forteo PI. “Do you have any inside info on the vaccines for COVID-19 during pregnancy?” OCOG Statement “Status of the Tocilizumab Shortage”? Genentech Statement “How would you treat polyarthritis in a renal transplant patient?” CONNECT WITH RheumNow ✩ Website - https://rheumnow.com/ ✩ Subscribe @ RheumNow: https://rheumnow.com/user/register ✩ LinkedIn - https://www.linkedin.com/in/john-cush... ✩ RheumNow LinkedIn: https://www.linkedin.com/company/rheu... ✩ Twitter - https://twitter.com/RheumNow Listen | PODCAST Apple Podcasts: https://podcasts.apple.com/us/podcast... Spotify: https://open.spotify.com/show/4Mjzj5j... Stitcher: https://www.stitcher.com/show/the-rhe... TuneIn: https://tunein.com/podcasts/Health--W... Podbean: https://rheumnow.podbean.com/ Got a Rheumatology question or case for Dr. Jack Cush? Record it here and we'll feature it on an upcoming podcast. Tell us your name and where you practice rheumatology. BackTalk:

New to RheumNow? Rheumnow.com is a news source dedicated to the field of Rheumatology. It is written by experts in the field, and written for rheumatologists and individuals working in related fields. In this episode, Dr. Jack Cush reviews the news and journal articles from the past week on RheumNow.com Metanalysis of JAK inhibition (tofacitinib & ruxolitinib) in alopecia areata - 12 studies, 346 Pts, Rx success (using SALT50 resp) was 66%, not influenced by age, sex, subtype. Alopecia recurrence seen w/in 3 mos of JAK D/C (in74%) https://t.co/CBSy4Kci80 Population study shows risk of H. Zoster in adults to be high among bDMARD and CTX, also increased w/ AZA and HCQ but not MTX SSZ or LEF users. Data from 254065, 1,826311 Pt-Yrs F/U, 6295 new DMARD users, 17024 incident HZ https://t.co/1TeOAWN9LB MMWR reports that during the COVID Delta variant era, Vaccination against COVID-19: - Reduces risk of COVID-19 infection 5X - Reduces risk of COVID-19 Hospitalization ⋗10X - Reduces risk of COVID-19 DEATH 10X https://t.co/rMRY84xX5F Study of 265 students w/ a positive COVID-19 test looked at 378 close contacts. Infx rates w both persons masked -7.7%, but when unmasked-32.4% (aORs = 4.9) https://t.co/fYdH33JbWR Effect of Diet on COVID Outcomes Probenecid, an OAT3 inhibitor, has inhibitory effects on RNA viruses (influenza, RSV) & decreases ACE2 expression. May have utility in COVID-19 as it was shown to inhibit SARS-CoV-2 replication in animal modelshttps://t.co/MClSjpqpSa Mease and colleagues have catalogued the current practices assessed in the CORRONA registry, noting that increased DMARD switching and decreased time on a given therapy by US physicians. https://t.co/cIWZw6KsuI A retrospective study of systemic sclerosis patients shows that acute hospitalization and mortality were not uncommon and were often linked to SSc-related lung disease. #RheumNow https://t.co/s5wSlndTrt Cases and Questions (AKA Back Talk) “What treatment do you use after 2 years of teraparitide in a woman with a hx of OP, spiral fracture while on a bisphosphonate”? Forteo PI. “Do you have any inside info on the vaccines for COVID-19 during pregnancy?” OCOG Statement “Status of the Tocilizumab Shortage”? Genentech Statement “How would you treat polyarthritis in a renal transplant patient?” CONNECT WITH RheumNow ✩ Website - https://rheumnow.com/ ✩ Subscribe @ RheumNow: https://rheumnow.com/user/register ✩ LinkedIn - https://www.linkedin.com/in/john-cush... ✩ RheumNow LinkedIn: https://www.linkedin.com/company/rheu... ✩ Twitter - https://twitter.com/RheumNow Listen | PODCAST Apple Podcasts: https://podcasts.apple.com/us/podcast... Spotify: https://open.spotify.com/show/4Mjzj5j... Stitcher: https://www.stitcher.com/show/the-rhe... TuneIn: https://tunein.com/podcasts/Health--W... Podbean: https://rheumnow.podbean.com/ Got a Rheumatology question or case for Dr. Jack Cush? Record it here and we'll feature it on an upcoming podcast. Tell us your name and where you practice rheumatology. BackTalk: https://rheumnow.com/submit-podcast-question-or-comment

In this Healthed lecture, Dr Lisa Beecham, GP; Member of Immunisation Committee for Gold Coast Primary Health Network, will explain the key differences between this new vaccine against shingles and what is currently available, and who might be best to be offered this option. She will also present the key reasons why patients might be convinced to pay for this otherwise unfunded vaccine.   See omnystudio.com/listener for privacy information.

Are unvaccinated people still at high risk for contracting COVID-19? Find out about this and more in today's PV Roundup podcast.

In this soundbite, William Schaffner, MD, speaks about whether concomitant receipt of recombinant zoster vaccine with another vaccine increases the risk of herpes zoster compared with receiving recombinant zoster vaccine alone. This topic was presented at the 2021 virtual Annual Conference on Vaccinology Research sponsored by the National Foundation for Infectious Diseases.

In this episode, we review the high-yield topic of Varicella-Zoster Virus from the Microbiology section. --- Send in a voice message: https://anchor.fm/medbulletsstep1/message

Dr. M. Frühwein über vertane Chancen Weitere Informationen: • https://www.rki.de/DE/Content/Infekt/Impfen/ImpfungenAZ/Zoster/Zoster.html • https://www.rki.de/DE/Content/Infekt/Impfen/Materialien/Faktenblaetter/Zoster.html Dieser Podcast-Service wird Ihnen ermöglicht mit freundlicher Unterstützung von GlaxoSmithKline GmbH & Co. KG Mehr Informationen zum Podcast unter: www.medical-tribune.de/medaudio

Merck's History of Crimes and Misdemeanors   Richard Gale and Gary Null Progressive Radio Network, March 18, 2021     As the Covid-19 pandemic wears on past a full year, several of the world’s top pharmaceutical companies have dominated the world headlines, notably Pfizer, Johnson & Johnson and AstraZeneca, along with the smaller start-ups such Moderna and Novavax. Each is now vying to usurp the coveted Covid-19 vaccine market. Prior to the pandemic, the vaccine market worldwide was only a small slice of the overall $1 trillion pharmaceutical market at about $24 billion annually. Now sales of the new generation of vaccines to fight the pandemic are poised to exceed global vaccine sales exponentially. Ronny Gal at the market analysis firm Bernstein estimates that Covid vaccine sales will reach $40 billion this year. We believe this is a very conservative estimate as newer vaccines come on line and with companies making efforts to outdo each other on its efficacy and safety profile. Moderna and Pfizer together are expected to earn $32 billion this year and we are not taking into account Russia’s Sputnik-V vaccine and now five approved in China. The frenetic race is underway to vaccinate billions of human beings naively standing in line after drinking from the government health agencies’ and the mainstream media’s cattle trowels of vaccine hype and propaganda. What is certain is that a new era of drug discovery has begun and all will be driven by the surge in vaccines’ new celebrity status. The very definition of a vaccine is now being redefined and it is clearly predictable that we will be witnessing prophylactic and therapeutic drugs being reevaluated as vaccines to leap-frog regulatory hurdles and to escape legal actions for product injury and death.    It may be surprising that the world’s second largest vaccine maker Merck is missing from the Covid vaccine cash cow. Along with the other two of the top three global vaccine makers, Glaxo and Sanofi, Merck exited the Covid vaccine arena after its candidates flopped in generating sufficient neutralizing antibodies in Phase 1 trials. Instead the company has shuffled its resources to develop two new novel drugs that will target serious risks of the body’s over-reactive immune response to SARS-CoV2 infection. Although we will not likely see a Merck Covid vaccine any time in the coming years, it has nevertheless lucratively reaped rewards after selling its Moderna stock late last year when the price went out the roof. Merck has also partnered with J&J to increase production of the latter’s vaccine in order to meet demand.   Merck's legacy of lawsuits for crimes and misdemeanors goes back at least to the 1960s. In 1975, it was busted by the SEC for illegal payments to foreign government officials from "approximately" 36 nations. The scam was orchestrated through personal bank accounts with the sole purpose of advancing drug approvals through foreign nations' regulatory medical agencies.     One of the largest scandals in modern medical history was the company's anti-inflammatory drug Vioxx that resulted in fines above $4.8 billion for causing over a minimum 60,000 deathsfrom sudden heart attacks and over 120,000 serious medical injuries. At its height, Vioxx was earning over $2 billion in revenues annually and it is estimated that 25 million patients were prescribed the medication. The securities class action suit against Merck alone reached $1 billion, placing it in the top 15 securities lawsuits in US corporate history. The main criminal charge was Merck's intentional withholding of scientific data about the drug's adverse cardiovascular side effects.    Years after the settlement, Ron Unz, the publisher of The American Conservative, undertook his own investigation to validate Vioxx's death toll. Analyzing the drug's adverse effects over a longer time period, Unz estimated Merck may have been responsible for nearly half a million premature deaths in elderly patients, the drug's primary target group. That is roughly the same number of total civilian, military and terrorist deaths from the US's military escapades in Afghanistan, Iraq and Pakistan combined.    Merck's settlement of 47,000 pending lawsuits for personal injuries and 265 class action cases was a small pittance for the harm Vioxx left in its wake. Merck executives were never properly punished for willingly concealing the drug's dangers in order to assure FDA approval.    In Australia, Merck's efforts to increase Vioxx profits employed other forms of malfeasance. The Australian government launched a class action suit against the drug maker on charges that employees allegedly schemed a fake scientific paper that was ghostwritten for a medical journal in order to put Vioxx into a positive light. Testimonies during the trial stated data was completely based upon "wishful thinking." Merck also founded the peer-reviewed journal Australasian Journal of Bone and Joint Medicine. The journal was a fraud; it was not properly peer-reviewed and its primary purpose was to promote Vioxx on the Australian continent.    Moreover, the class action lawsuit contained Merck emails accessed by Australian officials. The company's internal communications allegedly ordered select employees to draft up a hit list of physicians who were critical of Vioxx. According to the documents, these physicians were targeted to be "neutralized" or "discredited." Some, including Dr. James Fries at Sanford University's medical school, were clinical investigators who happened to speak out about the drug's shortcomings. One email stated, "We may need to seek them out and destroy them where they live..."     But Merck's troubles with the dangers of its products, falsifying data about drugs' efficacy and safety and exaggeration of medical claims go back sixty years. In the 1960s, the FDA discovered that the drug maker's arthritis medication Indocin had not been properly tested for efficacy and its adverse effects were being completely ignored.  In the 1970s, Merck's drug dietheylstilbestrol (DES) prescribed for the prevention of miscarriages caused a flurry of vaginal cancer cases and other gynecological disorders. Merck had all along known that DES was carcinogenic based upon its own animal clinical trials. In 2007, its cholesterol drug Zetiawas shown to increase liver disease. Again Merck had known about Zetia's liver risks but withheld the clinical trial's damning results.    It would also appear that Merck has managed to hijack US courts. This includes an early 2019 ruling by Trump's corporate-friendly US Supreme Court to side with the drug maker and squash hundreds of lawsuits for failing to issue warnings that its osteoporosis drug Fosamax's may contribute to debilitating bone fractures. A federal court in California found that Merck committed perjury for lying in a patent infringement case against Gilead Sciences over the latter's blockbuster Hepatitis C drug Sovaldi. The judge ruled that Merck carried out a "systematic and outrageous deception in conjunction with unethical business practices and litigation misconduct."  It turned out that Merck's patent claims were a sham and orchestrated by its legal division.   Besides pushing through the FDA dangerous medications onto the market, the company has also found itself in the courtroom on many occasions for allegedly price-fixing, routinely defrauding and overbilling states' Medicare and Medicaid programs, and violating the Anti-Kickback Statute. In 2006, the IRS went after Merck for owing almost $2 billion in back taxes. According to the Wall Street Journal, Merck partnered with a British bank to create an offshore subsidiary in tax-friendly Bermuda to divert taxable revenue on its bestselling cholesterol drugs Zocor and Mevacor through a patent scheme. The company ran the operation for ten years before the FDA uncovered the racket.    Merck is America's leading vaccine manufacturer. Despite public perception and the ruse that vaccines are somehow safer and more effective than pharmaceutical drugs in general, it is the same industry and corporate culture that manufactures both. Currently Merck markets vaccines for Haemophilus B, Hepatitis A and Hepatitis B (individually and in combination), human papilomavirus (Gardasil), Measles, Mumps and Rubella (MMR), pneumococcal, rotavirus, varicella (chickenpox) and Zoster virus (for shingles). In 2010, Merck obtained exclusive rights to MassBiologics’ vaccine portfolio. The consequence is that Merck's Adult Vaccine Portfolio expanded to include 9 of the 10 vaccines on the CDC's adult immunization schedule. The company now holds almost a full monopoly on the government's recommended vaccines   On its website, the FDA assures the public that "Vaccines, as with all products regulated by the FDA, undergo a rigorous review of laboratory and clinical data to ensure the safety, efficacy, purity and potency of these products."  However, not a single one of Merck's vaccines has ever been tested in a scientifically viable double-blinded placebo controlled trial. In each case, the placebo in the control group was not inert, such as the use of sterile saline. Rather Merck only tested its vaccines with the viral component against a faux placebo containing the same ingredients, including aluminum, but minus the virus. Known as a "carrier solution," the standard scientific protocol does not designate it as a proper placebo for measuring the efficacy and disease risks of a drug. And in the case of Gardasil, the trial was statistical trickery to mask Gardasil's adverse effects. One placebo group received the company’s proprietary adjuvant amorphous aluminum hydroxyphospate sulfate (AAHS), a known neurotoxin. The adjuvant has yet to be properly tested for safety. One of the more serious risks of aluminum adjuvants is the triggering of an extreme autoimmune response, what Israeli immunologist Yehuda Schoenfeld has called “autoimmue/inflammatory syndrome induced by adjuvants.”   In the Cochrane Database Collaboration’s 2016 analysis of Merck's Gardasil, the investigators were so alarmed they filed a complaint against the European Medical Agency for failing to adequately assess the vaccine's neurological harms. More recently, a meta-analysis published in Systemic Reviews journal concluded “HPV vaccines increased serious nervous system disorders and general harms.”   Robert Kennedy Jr is currently taking steps to sue Merck over the Gardasil deception. Kennedy's in-depth investigations through his Children's Health Defense organization has uncovered evidence that the vaccine increases birth defects in children conceived of HPV-vaccinated moms; miscarriages have increased 2000 percent above normal, and girls are experiencing serious reproductive complications, including infertility, at approximately ten-fold above the normal rate. During an interview on the Progressive Radio Network, Kennedy noted that there was 10 times greater risk of dying from cervical cancer among Gardasil trial participants compared to the general public. There is a 10-fold increase for ovarian failure, and 1 in 37 girls who receive the vaccine will experience an autoimmune disease after 6 months of receiving the series of injections. When we consider that 1 in 37,000 women have a chance of dying from cervical cancer, it puts HPV vaccines into a completely different light. Sadly, across the nation, politicians from both sides of the aisle in state legislatures, notably Governor Andrew Cuomo in New York, are seemingly doing Merck's bidding to mandate Gardasil for all girls and boys upon entering school.    Based upon Kennedy's research and documents received from Freedom of Information Act filings, during Merck's own Gardasil clinical trials, 2.3 percent of girls and women between the ages of 9 through 26 developed a serious autoimmune disease and crippling neurological disorders within seven months of vaccination. The most frequent adverse effects were arthritis and anthropathy, autoimmune thyroiditis, celiac disease, hyperthyroidism and hypothyroidism, inflammatory bowel disease, psoriasis, Raynaud's Phenomenon, rheumatoid arthritis and uveitis. In other words, it was the aluminum adjuvant responsible for this enormous suffering. He stated that according to Merck's own statistics, girls are one hundred times more likely to experience a serious adverse effect from the vaccine than to be protected from cervical cancer.    In a 2012 article published in the Journal of Law and Medical Ethics, researchers at the University of British Columbia wrote that ever since Gardasil was approved in 2006, Merck has engaged in an "overly aggressive marketing strategies and lobbying campaigns aimed at promoting Gardasil as a mandatory vaccine."  One strategy Merck has employed is to take advantage of FDA loopholes to fast track its drugs. In the case of its expanded Gardasil-9 for adults between the ages of 27 to 45, the company applied for fast tracking two days after the Journal of Toxicological and Environmental Health published a study that the HPV vaccine was lowering the probability of pregnancy for women in their 20s.   Unfortunately, the media has indiscriminately colluded with Merck. Drug companies, according to Kennedy, pay $4.5 billion to the major media networks and publications to promote their drugs. And none of the media outlets are willing to sacrifice their profits for advertising drugs on moral and ethical grounds.    Another scandal erupted within Merck's vaccine business in 2010 after two whistleblowers gave testimony that the mumps' component in its Measles-Mumps-Rubella (MMR) vaccine was based on fraudulent data about it's efficacy, and the company knowingly proceeded in order to corner the mumps vaccine market. Merck had been defrauding the US government, which purchases the MMR, for over a decade. The government and two Merck whistleblowers, virologists Stephen Krahling and Joan Wlochowski, filed a lawsuit against Merck for being in violation of the False Claims Act. According to the charges, Merck had "falsified its mumps vaccine test results to hit an efficacy rate of 95 percent. The company achieved this by adding "animal antibodies to a blood sample to give the impression of increased antibodies." This would certainly explain why mumps outbreaks in summer camps and on college campuses are found to occur among those vaccinated.    Merck has gained enormous political and social influence over the national perception about vaccines.  One example is Merck's behind the scenes aggression against the flim Vaxxed.  When the documentary film was officially selected to screen during the 2016 Tribeca Film Festival in Manhattan, we discovered in an earlier report that Merck left its fingerprints on the film's removal and censorship. The Alfred Sloan Foundation is the festival's largest sponsor; pro-vaccine advocate Bill Gates is also a notable contributor. One of the leading persons on the Foundation's board of trustees was Dr. Peter Kim.  Kim happens to be the former president of Merck's Research Laboratories who was directly responsible for the launch of Gardasil and Merck's other vaccines for the Zoster virus and rotavirus. The film presents a harsh indictment against Dr Julie Gerberding, the former head of the CDC who allegedly coordinated the cover up of data that confirmed thimerosal's role in the onset of autism. After managing the agency's operations to mine sweep the data and generate new studies with public funds to suggest thimerosal's safety, Gerberding accepted her reward from the pharmaceutical industry by becoming the head of Merck's vaccine division. In addition, according to the whistleblowing of a senior CDC scientist, Dr. William Thompson, Gerberding was allegedly responsible for destroying the CDC's research that showed African American boys were at a substantially higher risk of becoming autistic from Merck's MMR vaccine. Fortunately, Dr. Thompson, who was present during the order to shred documents, saved copies which he subsequently turned over to Congressman Bill Posy and an independent biologist Prof. Brian Hooker. Since then, Congress has refused to hold hearings thereby supporting the cover-up.    All told, these examples of Merck's culture of greed, deception, political maneuvering and aggression has collectively injured countless people. Its prime directive is selling drugs; its history of crimes and misdemeanors should indicate the company holds little integrity in its commitment to prevent and treat disease. The full extent of the casualties from Merck's drugs and vaccines may never be properly calculated. For firms such as Merck, Pfizer and Johnson and Johnson, injuries and deaths are the necessary collateral damage of getting poorly tested products on the market and as fast as possible.    Can we really trust such a company with such a criminal reputation to be forthright about its product’s safety records? Therefore we recommend people to support the efforts of Bobby Kennedy and the Children's Health Defense in its lawsuit against Merck's Gardasil. A victory may well weaken the entire edifice of vaccine pseudoscience and the public will realize that for decades it has been little more than a house of cards.

In this Healthed lecture, Prof Tony Cunningham AO, FAHMS, Infectious Diseases Physician; Director, Centre for Virus Research at The Westmead Institute for Medical Research, outlines the practical steps that can be taken to improve vaccine access and uptake in older people, an update on upcoming changes to the schedule, examine when unfunded vaccines are still clinically important, preview the upcoming new and important zoster vaccine and explains how adult immunisations need to be timed in the midst of the COVID vaccine roll-out. See omnystudio.com/listener for privacy information.

Episódio de hoje sobre uma condição muito comum! Raphael, Kaue e Pedro falam sobre 4 clinicagens de Herpes Zoster. Quando internar? Qual a melhor opção para analgesia? Quais os desfechos são afetados pelo tratamento? E a vacina? Em caso de dúvidas, críticas ou sugestões, entra em contato com a gente no Twitter ou Instagram no @tadeclinicagem ou manda um e-mail para tadeclinicagem@gmail.com. MINUTAGEM. (3:02) Uso de antivirais e corticoide (8:09) Corticoide (8:56) Quando internar? (11:59) Complicações por H. Zoster (14:28) Manifestações atípicas (23:39) Tratamento intra-hospitalar (24:53) Cuidados na internação (25:30) Controle da dor aguda (27:16) Neuralgia pos herpética (31:55) Vacinação (35:48) Resposta do desafio da semana anterior (36:20) Desafio da semana (36:40) Salves REFERÊNCIAS 1. Treatment of herpes zoster in the immunocompetent host. Uptodate Fev 2021. Mary A Albrecht 2. BEUTNER, Karl R. et al. Valaciclovir compared with acyclovir for improved therapy for herpes zoster in immunocompetent adults. Antimicrobial Agents and Chemotherapy, v. 39, n. 7, p. 1546-1553, 1995. 3. POLSO, A. K.; LASSITER, J. L.; NAGEL, J. L. Impact of hospital guideline for weight‐based antimicrobial dosing in morbidly obese adults and comprehensive literature review. Journal of clinical pharmacy and therapeutics, v. 39, n. 6, p. 584-608, 2014. 4. Vaccination for the prevention of shingles. Mary A Albrecht, Myron J Levin. Uptodate 2021. 5. LAL, Himal et al. Efficacy of an adjuvanted herpes zoster subunit vaccine in older adults. New England Journal of Medicine, v. 372, n. 22, p. 2087-2096, 2015. 6. Schmader, K. Herpes Zoster. Annals of Internal Medicine, 169(3). 2018 7. HAN, Ying et al. Corticosteroids for preventing postherpetic neuralgia. Cochrane Database of Systematic Reviews, n. 3, 2013. 8. Chen, N. et al. Antiviral treatment for preventing postherpetic neuralgia. Cochrane Database Syst. Rev. 2, CD006866 (2014). 9. Mehta, S. K. et al. Rapid and sensitive detection of varicella zoster virus in saliva of patients with herpes zoster. J. Virol. Methods 193, 128–130 (2013). 10. Solomon, C. G., Johnson, R. W. & Rice, A. S. C. Postherpetic neuralgia. N. Engl. J. Med. 371, 1526–1533 (2014). 11. McNicol, E. D., Midbari, A. & Eisenberg, E. Opioids for neuropathic pain. Cochrane Database Syst. Rev. 8, CD006146 (2013). 12. Gershon, A., Breuer, J., Cohen, J. et al. Varicella zoster virus infection. Nat Rev Dis Primers 1, 15016 (2015). 

Dr. Rosenblum preempts his upcoming Ultrasound Guided Interventional Pain Course for Physiatry and Pain Physicians on February 28, 2021 with a Journal club describing the Erector Spinae Plane Block.     Subscribe for Ultrasound Course Calendar, Discounts & Board Materials * indicates required Email Address * First Name Last Name     February 7, 2020 Ultrasound Guided Pain Procedures for Emergency Room Physicians February 28, 2020 Ultrasound Guided Pain Procedures in the Pain Office March 14, 2020 Ultrasound Guided Regional Anesthesia for  Anesthesiologists Find out More! Private Session Register on Link (for any day)- Set Day and Time Separately with Dr. Rosenblum Sign Up and Schedule a Private Session 4 Hour CME Webinar Access 2 Hour Hands on (in Person in NY or via Zoom) Tips on Safe Integration into your Practice Billing Register Now!         Reference   Krishnan S, Cascella M. Erector Spinae Plane Block. [Updated 2020 Jul 4]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2020 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK545305/ EnesAydinbEmreSengunaAtifBayramogluaHaci AhmetAlicibHigh-thoracic ultrasound-guided erector spinae plane block for acute herpes zoster pain management in emergency department. The American Journal of Emergency Medicine. Volume 37, Issue 2, February 2019, Pages 375.e1-375.e3ErdalTekinaAliAhiskalioglubMuhammed   

Dr. Rosenblum preempts his upcoming Ultrasound Guided Interventional Pain Course for Emergency Medicine Physicians on February 7, 2021 with a Journal club describing the Erector Spinae Plane Block.   Subscribe for US Course Schedule, Calendar & Discounts! * indicates required Email Address * First Name Last Name     February 7, 2020 Ultrasound Guided Pain Procedures for Emergency Room Physicians February 28, 2020 Ultrasound Guided Pain Procedures in the Pain Office March 14, 2020 Ultrasound Guided Regional Anesthesia for  Anesthesiologists Find out More! Private Session Register on Link (for any day)- Set Day and Time Separately with Dr. Rosenblum Sign Up and Schedule a Private Session 4 Hour CME Webinar Access 2 Hour Hands on (in Person in NY or via Zoom) Tips on Safe Integration into your Practice Billing Register Now!         Reference   Krishnan S, Cascella M. Erector Spinae Plane Block. [Updated 2020 Jul 4]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2020 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK545305/ EnesAydinbEmreSengunaAtifBayramogluaHaci AhmetAlicibHigh-thoracic ultrasound-guided erector spinae plane block for acute herpes zoster pain management in emergency department. The American Journal of Emergency Medicine. Volume 37, Issue 2, February 2019, Pages 375.e1-375.e3ErdalTekinaAliAhiskalioglubMuhammed   

Merck’s History of Crimes and Misdemeanors Merck’s History of Crimes and Misdemeanors   Richard Gale and Gary Null Progressive Radio Network, Which private corporation has likely been responsible for the deaths of more innocent people than any terrorist organization or military regime change in Afghanistan, Iraq, Libya, Syria and elsewhere?  For us, the answer is evident:  Merck and Company. Iatraogenic medicine, or medical error, is now the third leading cause of death in the US after cardiovascular disease and cancer. The majority of these deaths are caused by FDA approved drugs’ adverse effects and from patients taking multiple medications without thorough clinical research to determine the safety of their synergistic effects.  Consequently our health agencies’ oversight and monitoring of drugs on the market is dismal.   One of the worst corporate deals the US government may have ever made in modern history was to acquire the American subsidiary of the German pharmaceutical firm Merck and Company during the first world war. Later in 1953, Merck acquired a competitive drug maker Sharp and Dohme, thereby establishing itself as America’s largest drug developer and manufacturer. Since then this corporate Medusa has ensnared thirteen other drug firms, including Scherring Plough, which it acquired for $41 billion. The two pharmaceutical giants had earned $47 billion in combined sales at the time the merger was finalized in 2009.   Merck’s life of criminal behavior was observed back in the 1970s. In 1975, it was busted by the SEC for illegal payments to foreign government officials from “approximately” 36 nations. The scam was orchestrated through personal bank accounts with the sole purpose of advancing drug approvals through foreign nations’ regulatory medical agencies.   One of the largest frauds in recent medical history was the company’s anti-inflammatory drug Vioxx that resulted in fines above $4.8 billion for causing over a minimum 60,000 deaths from sudden heart attacks and over 120,000 serious medical injuries. At its height, Vioxx was earning over $2 billion in revenues annually and it is estimated that 25 million patients were prescribed the medication. The securities class action suit against the company alone reached $1 billion, placing it in the top 15 securities lawsuits in US corporate history. The centerpiece of the crime was Merck’s intentional withholding of scientific data about the drug’s adverse cardiovascular side effects.   Years after the settlement, Ron Unz, the publisher of The American Conservative, undertook his own investigation to validate Vioxx’s death toll. Analyzing the drug’s adverse effects over a longer time period, Unz estimated Merck may have been responsible for nearly half a million premature deaths in elderly patients, the drug’s primary target group. That is roughly the same number of total civilian, military and terrorist deaths from the US’s military escapades in Afghanistan, Iraq and Pakistan combined.   Merck’s settlement of 47,000 pending lawsuits for personal injuries and 265 class action cases was a small pittance for the harm Vioxx left in its wake. Merck executives were never properly punished for willingly concealing the drug’s dangers in order to assure FDA approval.   In Australia, Merck’s efforts to increase Vioxx profits employed other forms of malfeasance. The Australian government launched a class action suit against the drug maker on charges that employees schemed a fake scientific paper that was ghostwritten for a medical journal in order to put Vioxx into a positive light. Testimonies during the trial stated data was completely based upon “wishful thinking.” Merck also founded the peer-reviewed journal Australasian Journal of Bone and Joint Medicine. The journal was a fraud; it was not properly peer-reviewed and its primary purpose was to promote Vioxx on the Australian continent.   Moreover, the class action lawsuit contained Merck emails accessed by Australian officials. The company’s internal communications ordered select employees to draft up a hit list of physicians who were critical of Vioxx. According to the documents, these physicians were targeted to be “neutralized” or “discredited.” Some, including Dr. James Fries at Sanford University’s medical school, were clinical investigators who happened to speak out about the drug’s shortcomings. One email said, “We may need to seek them out and destroy them where they live…”   Efforts to target critics for harassment is not limited to Merck. Earlier, Monsanto earned a similar reputation. The Monsanto’s parent company Bayer had to release a public apology for the discovery of a Monsanto hit list of 200 French journalists and politicians who opposed glyphosate and its GMO crops. It has acted similarly in other countries including the US, according to veteran journalist Carey Gillam.  The list originated from the multinational public relations firm Fleishman Hillard. Merck has also employed Fleishman Hillard as well as Monsanto’s other notorious PR firm Ketchum. One of Merck’s Executive Directors, Ian McConnell, earlier served as a vice president at Fleishman. The PR firm’s senior adviser on healthcare Dr. Lukas Pfister, was at Merck for 25 years in its government affairs unit. Merck’s revolving door is not limited to our federal health agencies, but also fully infiltrates some of the world’s most shadowy international PR firms that specialize in whitewashing the public images of executive elites, corporations and in the case of the PR firm Burson-Marsteller even dictators. Following the Vioxx case, Merck had hired B-Marsteller to clean up its public image. MSNBC reported back in 2009, “When evil needs public relations, evil has Burson-Marsteller on speed dial.”   But Merck’s efforts to conceal the dangers of its products, falsify data about drugs’ efficacy and safety and exaggeration of medical claims go back sixty years. In the 1960s, the FDA discovered that the drug maker’s arthritis medication Indocin had not been properly tested for efficacy and its adverse effects were being completely ignored.  In the 1970s, Merck’s drug dietheylstilbestrol (DES) prescribed for the prevention of miscarriages caused a flurry of vaginal cancer cases and other gynecological disorders. Merck had all along known that DES was carcinogenic based upon its own animal clinical trials. In 2007, its cholesterol drug Zetia was shown to increase liver disease. Again Merck had known about Zetia’s liver risks but withheld the clinical trial’s damning results.   It would also appear that Merck has managed to hijack US courts as well. This includes an early 2019 ruling by Trump’s corporate-friendly US Supreme Court to side with the drug maker and squash hundreds of lawsuits for failing to issue warnings that its osteoporosis drug Fosamax’s may contribute to debilitating bone breaks. A federal court in California found that Merck committed perjury for lying in a patent infringement case against Gilead Sciences over the latter’s blockbuster Hepatitis C drug Sovaldi. The judge ruled that Merck carried out a “systematic and outrageous deception in conjunction with unethical business practices and litigation misconduct.”  It turned out that Merck’s patent claims were a sham and orchestrated by its legal division.   Besides pushing through the FDA dangerous medications onto the market, the company has also found itself in the courtroom on many occasions for price-fixing, routinely defrauding and overbilling states’ Medicare and Medicaid programs, and violating the Anti-Kickback Statute. In 2006, the IRS went after Merck for owing almost $2 billion in back taxes. According to the Wall Street Journal, Merck partnered with a British bank to create an offshore subsidiary in tax-friendly Bermuda to divert taxable revenue on its bestselling cholesterol drugs Zocor and Mevacor through a patent scheme. The company ran the operation for ten years before the FDA uncovered the racket.   Merck is America’s leading vaccine manufacturer. Despite public perception and the ruse that vaccines are somehow safer and more effective than pharmaceutical drugs in general, it is the same industry and corporate culture that manufactures both them. Currently Merck markets vaccines for Haemophilus B, Hepatitis A and Hepatitis B (individually and in combination), human papilomavirus (Gardasil), Measles, Mumps and Rubella (MMR), pneumococcal, rotavirus, varicella (chickenpox) and Zoster virus (for shingles). More recently it has jumped into the coronavirus vaccine race. In 2010, Merck obtained exclusive rights to MassBiologics vaccine portfolio. The consequence is that Merck’s Adult Vaccine Portfolio expanded to include 9 of the 10 vaccines on the CDC’s adult immunization schedule. The company now holds almost a full monopoly on the government’s vaccines   On its website, the FDA assures the public that “Vaccines, as with all products regulated by the FDA, undergo a rigorous review of laboratory and clinical data to ensure the safety, efficacy, purity and potency of these products.”  However, except for Gardasil, not a single one of Merck’s vaccines has ever been tested in a scientifically viable double-blinded placebo controlled trial. In each case, the placebo in the control group was not inert, such as the use of sterile saline. Rather Merck only tested the vaccine with the viral component against a faux placebo containing the same ingredients, including aluminum, but minus the virus. Known as a “carrier solution,” the standard scientific protocol does not designate it as a proper placebo for measuring the efficacy and disease risks of a drug. And in the case of Gardasil, the trial was statistical trickery to mask Gardasil’s adverse effects. Therefore the FDA’s claim is patently false. None of Merck’s vaccines have ever undergone a “rigorous review” prior to regulatory approval.   Although not completely innocent from internal unfairness and conflicts of interest, the Cochrane Database Collaboration arguably remains the most reliable resource for analysis of drugs, vaccines and medical devices in the evidence-based medical establishment. In its 2016 analysis of Merck’s human papillomavirus vaccine Gardasil, the investigators were so alarmed they filed a complaint against the European Medical Agency for failing to adequately assess the vaccine’s neurological harms.   As we have recently witnessed with Monsanto’s Roundup and Bayer’s settlement of $10 billion to cover 80,000 lawsuits, Gardasil may very well become the company’s Achilles heel. The Gardasil scandal may very well begin to topple the vaccine regime and raise the public’s already increasing awareness and distrust in the official mantra that vaccines are safe and effective. The development, scientific rationale, fraudulent clinical trials and data reporting, and inside negotiations with federal health officials to market the vaccine to pre-teen and teen girls and boys, is a story riddled with misconduct. Today it is Merck’s third largest revenue-generating drug after its cancer drug Keytruda and diabetes drug Januvia, earning $3.1 billion in 2018. Its MMR vaccine is fifth having earned $1.8 billion. Gardasil’s success has nothing to do with the prevention of an urgent national health need. Instead it was a business strategy through Merck’s influence over our nation’s regulatory agencies and state politicians whose election campaigns it funds.   In 2018, a French oncologist, Dr. Gerard Delepine, stumbled upon a correlation between the increase of cervical cancer rates with the rising rates of Gardasil vaccinations. Delepine also compared France, which was deliberating on whether to mandate HPV vaccination, with other countries that relied upon pap smears as a preventative measure against cervical cancer. He observed that in all countries that prioritized pap smears, cervical cancer rates were decreasing; whereas, in those countries with higher HPV vaccination compliance, the rates increased. In his letter to the French government in defiance of Merck’s lobbying efforts, Delephine stated:   “A compulsory health measure should not be based on faith in vaccination or hidden conflicts of interest, but on proven facts, verifiable by every citizen. However, the facts established by the official records of cancer registries show that HPV vaccination does not protect against invasive cancer of the cervix, but seems rather to maintain its frequency at a high level and sometimes even increase it.”   An article published in the French journal Agoravox noted that other national health ministries are coming around to acknowledge that Gardasil is an extremely unsafe vaccine. Japan, Austria and Denmark no longer promote it due to is trail of injuries with fatal consequences. Public demonstrations against Merck’s Gardasil have occurred in Japan, Colombia, and Ireland.   Yet none of these efforts to warn the public about Gardasil’s risks have reached the American media. Hopefully this may change. Medical researchers at the University of South Alabama presented their paper at the Society of Gynecologic Oncology’s annual conference. There is great disparity between HPV vaccine compliance across Alabama counties, which range anywhere between 33 and 66 percent. Yet the epidemiological data suggests there is no evidence that Gardasil lowered cancer rates in counties with higher vaccine uptake. Moreover, there is zero chance of pre-teens and teens getting cervical cancer. The average age for the onset of the cancer is 50 years. Nor has the vaccine been on the market long enough to determine whether it protects a woman when she reaches even close to that age. Its product insert for physicians states the vaccine “may not result in protection in all vaccine recipients” and it “has not been demonstrated to prevent HPV-related CIN 2/3 [abnormal pre-cancerous cervical cells] or worse in women older than 26 years of age.” Consequently, there is no scientific rationale for states to mandate the HPV vaccine for schoolchildren let alone even vaccinating them in the first place. In addition, the federal agencies and Merck market the vaccine under a false pretext that HPV infection is the leading cause of cervical cancer; correctly, only a third of cervical cancer cases are caused by the virus.   Robert Kennedy Jr is currently taking steps to sue Merck over the Gardasil deception. Merck’s first effort to have the class action suit dismissed was overturned by the court. Kennedy’s in-depth investigations through his Children’s Health Defense organization has uncovered evidence that the vaccine increases birth defects in children conceived of HPV-vaccinated moms; miscarriages have increased 2000 percent above normal, and girls are experiencing serious reproductive complications, including infertility, at approximately ten-fold above the normal rate. During an interview on the Progressive Radio Network, he noted that there was 10 times greater risk of dying from cervical cancer among Gardasil trial participants compared to the general public. There is a 10-fold increase for ovarian failure, and 1 in 37 girls who receive the vaccine will experience an autoimmune disease after 6 months of receiving the series of injections. When we consider that 1 in 37,000 women have a chance of dying from cervical cancer, it puts HPV vaccines into a completely different light. Sadly, across the nation, politicians from both sides of the aisle in state legislatures, notably Governor Andrew Cuomo in New York, are doing Merck’s bidding to mandate Gardasil for all girls and boys upon entering school.   Based upon Kennedy’s research and documents received from Freedom of Information Act filings, during Merck’s own Gardasil clinical trials, 2.3 percent of girls and women between the ages of 9 through 26 developed a serious autoimmune disease and crippling neurological disorders within seven months of vaccination. Among the 10,700 who received the actual vaccine, 245 (2.3%) had an autoimmune disorder; among the 9,412 who received either an “AAHS Control” — the aluminum hydrophosphate sulfate adjuvant solution with other ingredients minus the HPV virus vectors, there were 218 (2.3%) life-threatening injuries. The most frequent adverse effects were arthritis and anthropathy, autoimmune thyroiditis, celiac disease, hyperthyroidism and hypothyroidism, inflammatory bowel disease, psoriasis, Raynaud’s Phenomenon, rheumatoid arthritis and uveitis. In other words, it was the aluminum adjuvant responsible for this enormous suffering. He stated during the Progressive Radio Network broadcast that according to Merck’s own statistics, girls are one hundred times more likely to experience a serious adverse effect from the vaccine than to be protected from cervical cancer.   In a 2012 article published in the Journal of Law and Medical Ethics, researchers at the University of British Columbia wrote that ever since Gardasil was approved in 2006, Merck has engaged in an “overly aggressive marketing strategies and lobbying campaigns aimed at promoting Gardasil as a mandatory vaccine.”  One strategy Merck has employed is to take advantage of FDA loopholes to fast track its drugs. In the case of its expanded Gardasil-9 for adults between the ages of 27 to 45, the company applied for fast tracking two days after the Journal of Toxicological and Environmental Health published a study that the HPV vaccine was lowering the probability of pregnancy for women in their 20s.   Unfortunately, the media has indiscriminately colluded with Merck’s scam. Drug companies, according to Kennedy, pay $4.5 billion to the major media networks and publications to promote their drugs. And none of the media outlets are willing to sacrifice their profits for advertising drugs on moral and ethical grounds.   Another scandal erupted within Merck’s vaccine business in 2010 after two whistleblowers gave testimony that the mumps’ component in its Measles-Mumps-Rubella (MMR) vaccine was based on fraudulent data about it’s efficacy, and the company knowingly proceeded in order to corner the mumps vaccine market. Merck had been defrauding According to the charges, Merck had “falsified its mumps vaccine test results to hit an efficacy rate of 95 percent. The company achieved this by adding “animal antibodies to a blood sample to give the impression of increased antibodies.” This would certainly explain why mumps outbreaks in summer camps and on college campuses are found to occur among those vaccinated.   Merck’s has gained enormous political and social influence over the national perception about vaccines.  One example is Merck’s behind the scenes aggression against the flim Vaxxed.  When the documentary film was officially selected to screen during the 2016 Tribeca Film Festival in Manhattan, we discovered in an earlier report that Merck left its fingerprints on the film’s removal and censorship. The Alfred Sloan Foundation is the festival’s largest sponsor; pro-vaccine advocate Bill Gates is also a notable contributor. One of the leading persons on the Foundation’s board of trustees was Dr. Peter Kim.  Kim happens to be the former president of Merck’s Research Laboratories who was directly responsible for the launch of Gardasil and Merck’s other vaccines for the Zoster virus and rotavirus. The film presents a harsh indictment against Dr Julie Gerberding, the former head of the CDC who coordinated the cover up of data that confirmed thimerosal’s role in the onset of autism. After managing the agency’s operations to mine sweep the data and generate new manipulated studies with public funds to suggest thimerosal’s safety, Gerberding accepted her reward from the pharmaceutical industry by becoming the head of Merck’s vaccine division. In addition, according to the whistleblowing of a senior CDC scientist, Dr. William Thompson, Gerberding was responsible for destroying the CDC’s research that showed African American boys were at a substantially higher risk of becoming autistic from Merck’s MMR vaccine. Fortunately, Dr. Thompson, who was present during the order to shred documents, saved copies which he subsequently turned over to Congressman Bill Posy and an independent biologist Prof. Brian Hooker. Since then, Congress has failed to hold hearings.   All told, these examples of Merck’s culture of greed, deception, political maneuvering and illegal aggression has collectively injured countless people. Merck is a global corporation. Its products, like Monsanto’s glyphoste, are marketed globally. To better understand Merck, the company should be perceived foremost as a cash cow for Wall Street. Its prime directive is selling drugs; its history of misdemeanors and criminal activities should indicate the company holds little integrity in its commitment to prevent and treat disease. The full extent of the casualties from Merck’s drugs and vaccines may never be properly calculated. For firms such as Merck and Monsanto, injuries and deaths are the necessary collateral damage of getting poorly tested products on the market and as fast as possible. A black box should be slapped on the Merck logo.   What is important at this moment is that many corporations are fast-tracking, without sufficient long-term animal and human clinical trials, Merck is now aggressively making efforts to beat out its competition with a Covid-19 vaccine.  Do we really want to trust such a company with this reputation with a Covid vaccine? Therefore we recommend people to support the efforts of Bobby Kennedy and the Children’s Health Defense in its lawsuit against Merck’s Gardasil. A victory may well weaken the entire edifice of vaccine pseudoscience and the public will realize that for decades it has been little more than a house of cards.

This episode covers varicella zoster virus!

Dr. Toney reviews the epidemiology and management of Varicella Zoster infections. He first discusses the prevalence and clinical presentation of this herpesvirus family infection. He points out the importance of recognizing the prodrome in patients before the complete outbreak occurs. He goes on to discuss the clinical complications of VZV disease, including ophthalmologic, multi-dermatomal, and disseminated infections. He next discusses the treatment options available to manage Zoster infections. The subject of available Zoster vaccines is then discussed, with a focus on the newer Recombinant Zoster Vaccine (RZV). Lastly, Dr. Toney presents a couple of photo case-studies.

El herpes. Un virus que tiene predilección por el ojo, que podemos tratar el brote agudo pero no podemos eliminarlo de nuestro organismo. Una de las infecciones más importantes del ojo, y a la vez de las menos conocidas. Hoy te cuento sus secretos. Este es el episodio sexto de la cuarta temporada del podcast de Ocularis, y lo dedicamos al herpes ocular. Si quieres saber más del tema, aquí te pongo información adicional del blog: MIR 2012 – Preguntas de oftalmología : Este artículo está dedicado a corregir y comentar las preguntas del examen de acceso a especialidad médica (MIR) del año 2012, donde cayó una pregunta (la 169) sobre una úlcera típica de herpes simplex, la úlcera dendrítica. Aprovecho el comentario de esta pregunta para hablar del herpes simple, de esta úlcera, de las diferencias de esta dendrita auténtica con la pseudodendrita del Zoster, etc. Métodos de contacto: Grupo de Telegram: https://t.me/ProyectoOcularis Blog: https://ocularis.es Email: proyecto.ocularis@gmail.com Twitter: @ocularistweet Facebook: https://www.facebook.com/proyecto.ocularis

This week we look at herpetic infections of the eye and skin focusing on diagnosis and management. https://media.blubrry.com/coreem/content.blubrry.com/coreem/Episode_41_0_Final_Cut.m4a Download One Comment Tags: Herpes, Herpetic Keratitis, Shingles, Zoster Show Notes Wilhelmus KR. Antiviral treatment and other therapeutic interventions for herpes simplex virus epithelial keratitis. Cochrane Database Syst Rev 2010. PMID: 21154352 American Academy of Ophthalmology: Herpes Simplex Virus Keratitis Treatment Guideline Read More

This week we look at herpetic infections of the eye and skin focusing on diagnosis and management. https://media.blubrry.com/coreem/content.blubrry.com/coreem/Episode_41_0_Final_Cut.m4a Download One Comment Tags: Herpes, Herpetic Keratitis, Shingles, Zoster Show Notes Wilhelmus KR. Antiviral treatment and other therapeutic interventions for herpes simplex virus epithelial keratitis. Cochrane Database Syst Rev 2010. PMID: 21154352 American Academy of Ophthalmology: Herpes Simplex Virus Keratitis Treatment Guideline Read More

Dr. Rosenblum Reviews Orofacial Pain and the Cervicogenic Headache (free version) For the Full Version Click Here Discussed in the Full Version of this Podcast: Cervicogenic Headache Tic Douloureux Trigeminal neuralgia Acute herpes zoster Postherpetic neuralgia Raeder's syndrome Geniculate neuralgia/Ramsay Hunt Syndrome Glosssopharyngeal neuralgia Superior Laryngeal neuralgia Hypoglossasal/vagus neuralgia Tolosa-Hunt syndrome Thalamic pain  SUNCT Pain Syndrome PainExam Podcast Download our App! For the Full Version Click Here For more information on Pain Management Topics and keywords Go to PainExam.com David Rosenblum, MD specializes in Pain Management and is the Director of Pain Management at Maimonides Medical Center and AABP Pain Managment For evaluation and treatment of a Painful Disorder, go to www.AABPPain.com 718 436 7246 DISCLAIMER: Doctor Rosenblum IS HERE SOLELY TO EDUCATE, AND YOU ARE SOLELY RESPONSIBLE FOR ALL YOUR DECISIONS AND ACTIONS IN RESPONSE TO ANY INFORMATION CONTAINED HEREIN. This podcasts is not intended as a substitute for the medical advice of physician to a particular patient or specific ailment.  You should regularly consult a physician in matters relating to yours or another's health.  You understand that this podcast is not intended as a substitute for consultation with a licensed medical professional.    Copyright © 2015 QBazaar.com, LLC  All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, recording or otherwise, without the prior written permission of the author.           References Benzon, HT.  Essentionals of Pain Management and Regional Anesthesia. Second ed. page 301-306

David Rosenblum, MD discusses diagnosis, pathology, prevention and treatment of Postherpetic Neuralgia. Discussed: Pathology of the Varicella Zoster infection Gabapentin Lyrica Amitriptyline Capsaicin Lidocaine patch Valacyclovir Zostavax- zoster vaccine   References Nagel MA, Postherpetic Neuralgia: New Perspectives on Pathogenesis and Treatment.  Pain Medicine News, 2015 Dworkin RH, Schmader KE.  Herpes Zoster and Postherpetic Neuralgia.  Essentials of Pain Medicine and Regional Anesthesia.  Second Edition. 2005 p. 386-393 DISCLAIMER: Doctor Rosenblum IS HERE SOLELY TO EDUCATE, AND YOU ARE SOLELY RESPONSIBLE FOR ALL YOUR DECISIONS AND ACTIONS IN RESPONSE TO ANY INFORMATION CONTAINED HEREIN. This podcasts is not intended as a substitute for the medical advice of physician to a particular patient or specific ailment.  You should regularly consult a physician in matters relating to yours or another's health.  You understand that this podcast is not intended as a substitute for consultation with a licensed medical professional.    Copyright © 2015 QBazaar.com, LLC  All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, recording or otherwise, without the prior written permission of the author.