Podcasts about rfs

Renewable Fuels Association President and CEO Geoff Cooper talks about the 20th anniversary of the Renewable Fuel Standard (RFS), which was part of the Energy Policy Act of 2005 signed by President George W. Bush on August 8 of that year at Sandia National Laboratory in Albuquerque, New Mexico. Read RFA's report on the RFS at Twenty.

Raidījumā Piespēle iepazīstam Kanādas nacionālo vasaras sporta veidu lakrosu. Tā ir viena no senākajām komandu sporta spēlēm pasaulē, radusies 12. gadsimtā. Pirmie to sāka spēlēt Ziemeļamerikas pamatiedzīvotāji. Latvijā šo sporta veidu šī gadsimta ievadā aizsāka Aigars Grīnbergs, bet pavisam nesen Latvijas vīriešu izlase Eiropas čempionātā izcīnīja augsto piekto vietu. Studijā viesojas Latvijas Lakrosa federācijas prezidents Nikolajs Karlsons, kurš stāsta plašāk par šī sporta veida attīstību pašu mājās. Nedēļas topā: Latvijas U-18 un jaunāku puišu basketbola izlase pārsteidz daudzus un Eiropas čempionātā aizkļūst līdz mačam par bronzas medaļām; Latvijas vīriešu basketbola izlase 17 vīru sastāvā dodas uz treniņnometni Slovēnijā, 9.augustā Triestē pirmā pārbaudes spēle; RFS futbolisti izstājas Čempionu līgas kvalifikācijas otrajā kārtā, “Riga” izglābjas Gruzijā un soļo tālāk Konferences līgā; Eiropas čempionātā pludmales volejbolā šoreiz latviešu pāriem dalīta piektā, devītā un 25.vieta; Eiropas čempionāta kvalifikācijā volejbolā sieviešu izlase piecos setos zaudē Bosnijai un Hercegovinai, bet sper soli tuvāk finālturnīram.

Atlicis tikai mēnesis līdz Eiropas čempionāta finālturnīra sākumam. Latvijas vīriešu basketbola izlase jau 27. augustā aizvadīs savu pirmo spēli pret Turciju. Tāpēc arī viss raidījums Piespēle veltīts Eiropas čempionātam basketbolā.  Ieklausāmies Eiropas basketbola čempionāta reklāmas rullīša filmēšanas aizkulisēs. Latvijas Radio tiešraidē pārraidīs visas Latvijas valstsvienības spēles, tās komentēs Andrejs Siliņš un Mārtiņš Kļavenieks, bet ekspertu studijā būs Māris Bergs un Uvis Helmanis. Rubrikā "Ciemos pie Gunāra Jākobsona" arī saruna par basketbolu. No 14. līdz 17. augustam Rīgā risināsies 1939. gada Eiropas vicečempiona Alfrēda Kraukļa tradicionālais piemiņas turnīrs basketbolā. Stāsta turnīra rīkotāji Jānis Labuts un Kristīne Karašniece-Bullīte. Nedēļas topā: RFS futbolistiem pamatīgs zaudējums  pret Malmes klubu Čempionu līgas kvalifikācijas otrās kārtas ievadā, “Riga” nosargā uzvaru Konferences līgas kvalifikācijas mačā; Latvijas izlases basketbolisti paraksta jaunus līgumus augsta līmeņa čempionātos - Kristers Zoriks pārceļas uz Spāniju, Mārcis Šteinbergs paliek Manrēsā, Kārlis Šiliņš - uz Turciju; Latvijas jaunie sportisti ar labiem rezultātiem startē Eiropas jaunatnes olimpiskajā festivālā Ziemeļmaķedonijā; Latvijas 20 gadīgo puišu izlases basketbolisti pēc sešu gadu pauzes atgriežas Eiropas elitē.

I veckans avsnitt snackar vi ner matcherna mot RFS och Öster, synar prestationerna, hyllar och ifrågasätter och pratar nyförvärv, byten och vad som egentligen händer med MFF:s spel just nu. Dessutom: VD Niclas Carlnén tackar för sig efter elva år, vad betyder det för klubbens framtid?Patreon blir du enklast här - Patreon.com/HDN

Šoreiz raidījumā Piespēle runājam par šahu un vienu no visu laiku izcilākajiem tā spēlētājiem - rīdzinieku Mihailu Tālu. Tāla zvaigzne pie pasaules šaha debesjuma uzmirdzēja 1960. gadā, kad viņš kļuva par pasaules čempionu. Diemžēl tronī izdevās noturēties vien gadu, pēc tam šo panākumu vairs atkārtot viņš nespēja. Kas īsti bija un joprojām ir Tāla fenomens, un kāds cilvēcīgi bija šahists ikdienā - par to saruna ar nule kā klajā nākušās grāmatas “Eksčempions. Mihails Tāls” autoru, šaha treneri un vēsturnieku Andri Tihomirovu. Nedēļas topā: RFS futbolisti soļo tālāk Čempionu līgas kvalifikācijā, “Audai” un “Daugavpilij” izstāšanās Konferences līgas pirmajā kārtā; “Latvijas Universitāte” arī nākamajā sezonā tomēr spēlēs apvienotajā basketbola līgā - turnīrā 14 komandas, Rīgas “Zeļļi” tomēr atsakās no vietas FIBA Eiropas kausa kvalifikācijā; Aļonai Ostapenko turpina neveikties visaugstākās raudzes tenisa turnīru finālos - zaudējums Vimbldonas dubultspēlēs un neizmantota iespēja kļūt par dubultspēļu ranga līderi.

Iowa Business Report Wednesday EditionJul. 16, 2025  Iowa Secretary of Agriculture and Land Stewardship Mike Naig on why the new federal RFS numbers are good news for Iowa's economy. 

Headlines on today's episode include:-USDA unveils farm security action plan-Chairman Thompson discusses National Farm Security Action Plan-Biofuel groups testify at EPA hearing on 2026-27 Renewable Fuel Standards-Petroleum groups push back on EPA's RFS proposal-Farmers say let's get the deals doneSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Dr. Diwakar Davar and Dr. Jason Luke discuss novel agents in melanoma and other promising new data in the field of immunotherapy that were presented at the 2025 ASCO Annual Meeting. TRANSCRIPT Dr. Diwakar Davar: Hello. My name is Diwakar Davar, and I am welcoming you to the ASCO Daily News Podcast. I'm an associate professor of medicine and the clinical director of the Melanoma and Skin Cancer Program at the University of Pittsburgh's Hillman Cancer Center. Today, I'm joined by my colleague and good friend, Dr. Jason Luke. Dr. Luke is a professor of medicine. He is also the associate director of clinical research and the director of the Phase 1 IDDC Program at the University of Pittsburgh's Hillman Cancer Center. He and I are going to be discussing some key advancements in melanoma and skin cancers that were presented at the 2025 ASCO Annual Meeting. Our full disclosures are available in the transcript of this episode.  Jason, it is great to have you back on the podcast. Dr. Jason Luke: Thanks again so much for the opportunity, and I'm really looking forward to it. Dr. Diwakar Davar: Perfect. So we will go ahead and start talking a little bit about a couple of key abstracts in both the drug development immunotherapy space and the melanoma space. The first couple of abstracts, the first two, will cover melanoma. So, the first is LBA9500, which was essentially the primary results of RELATIVITY-098. RELATIVITY-098 was a phase 3 trial that compared nivolumab plus relatlimab in a fixed-dose combination against nivolumab alone for the adjuvant treatment of resected high-risk disease. Jason, do you want to maybe give us a brief context of what this is? Dr. Jason Luke: Yeah, it's great, thanks. So as almost all listeners, of course, will be aware, the use of anti–PD-1 immunotherapies really revolutionized melanoma oncology over the last 10 to 15 years. And it has become a standard of care in the adjuvant setting as well. But to review, in patients with stage III melanoma, treatment can be targeted towards BRAF with BRAF and MEK combination therapy, where that's relevant, or anti–PD-1 with nivolumab or pembrolizumab are a standard of care. And more recently, we've had the development of neoadjuvant approaches for palpable stage III disease. And in that space, if patients present, based on two different studies, either pembrolizumab or nivolumab plus ipilimumab can be given prior to surgery for somewhere in the 6- to 9-week range. And so all of these therapies have improved time-to-event endpoints, such as relapse-free or event-free survival. It's worth noting, however, that despite those advances, we've had a couple different trials now that have actually failed in this adjuvant setting, most high profile being the CheckMate-915 study, which looked at nivolumab plus ipilimumab and unfortunately was a negative study. So, with RELATIVITY-047, which was the trial of nivolumab plus relatlimab that showed an improvement in progression-free survival for metastatic disease, there's a lot of interest, and we've been awaiting these data for a long time for RELATIVITY-098, which, of course, is this adjuvant trial of LAG-3 blockade with relatlimab plus nivolumab. Dr. Diwakar Davar: Great. So with that, let's briefly discuss the trial design and the results. So this was a randomized, phase 3, blinded study, so double-blinded, so neither the investigators knew what the patients were getting, nor did the patients know what they were getting. The treatment investigational arm was nivolumab plus relatlimab in the fixed-dose combination. So that's the nivolumab standard fixed dose with relatlimab that was FDA approved in RELATIVITY-047. And the control arm was nivolumab by itself. The duration of treatment was 1 year. The patient population consisted of resected high-risk stage III or IV patients. The primary endpoint was investigator-assessed RFS. Stage and geography were the standard stratifying factors, and they were included, and most of the criteria were balanced across both arms. What we know at this point is that the 2-year RFS rate was 64% and 62% in the nivolumab and nivolumab-combination arms, respectively. The 2-year DMFS rate was similarly equivalent: 76% with nivolumab monotherapy, 73% with the combination. And similar to what you had talked about with CheckMate 915, unfortunately, the addition of LAG-3 did not appear to improve the RFS or DMFS compared to control in this patient population. So, tell us a little bit about your take on this and what do you think might be the reasons why this trial was negative? Dr. Jason Luke: It's really unfortunate that we have this negative phase 3 trial. There had been a lot of hope that the combination of nivolumab with relatlimab would be a better tolerated combination that increased the efficacy. So in the metastatic setting, we do have 047, the study that demonstrated nivolumab plus relatlimab, but now we have this negative trial in the adjuvant setting. And so as to why exactly, I think is a complicated scenario. You know, when we look at the hazard ratios for relapse-free survival, the primary endpoint, as well as the secondary endpoints for distant metastasis-free survival, we see that the hazard ratio is approximately 1. So there's basically no difference. And that really suggests that relatlimab in this setting had no impact whatsoever on therapeutic outcomes in terms of efficacy. Now, it's worth noting that there was a biomarker subanalysis that was presented in conjunction with these data that looked at some immunophenotyping, both from circulating T cells, CD8 T cells, as well as from the tumor microenvironment from patients who were treated, both in the previous metastatic trial, the RELATIVITY-047 study, and now in this adjuvant study in the RELATIVITY-098 study. And to briefly summarize those, what was identified was that T cells in advanced melanoma seemed to have higher expression levels of LAG-3 relative to T cells that are circulating in patients that are in the adjuvant setting. In addition to that, there was a suggestion that the magnitude of increase is greater in the advanced setting versus adjuvant. And the overall summary of this is that the suggested rationale for why this was a negative trial may have been that the target of LAG-3 is not expressed as highly in the adjuvant setting as it is in the metastatic setting. And so while the data that were presented, I think, support this kind of an idea, I am a little bit cautious that this is actually the reason for why the trial was negative, however. I would say we're not really sure yet as to why the trial was negative, but the fact that the hazard ratios for the major endpoints were essentially 1 suggests that there was no impact whatsoever from relatlimab. And this really makes one wonder whether or not building on anti–PD-1 in the adjuvant setting is feasible because anti–PD-1 works so well. You would think that even if the levels of LAG-3 expression were slightly different, you would have seen a trend in one direction or another by adding a second drug, relatlimab, in this scenario. So overall, I think it's an unfortunate circumstance that the trial is negative. Clearly there's going to be no role for relatlimab in the adjuvant setting. I think this really makes one wonder about the utility of LAG-3 blockade and how powerful it really can be. I think it's probably worth pointing out there's another adjuvant trial ongoing now of a different PD-1 and LAG-3 combination, and that's cemiplimab plus fianlimab, a LAG-3 antibody that's being dosed from another trial sponsor at a much higher dose, and perhaps that may make some level of difference. But certainly, these are unfortunate results that will not advance the field beyond where we were at already. Dr. Diwakar Davar: And to your point about third-generation checkpoint factors that were negative, I guess it's probably worth noting that a trial that you were involved with, KeyVibe-010, that evaluated the PD-1 TIGIT co-formulation of vibostolimab, MK-4280A, was also, unfortunately, similarly negative. So, to your point, it's not clear that all these third-generation receptors are necessarily going to have the same impact in the adjuvant setting, even if they, you know, for example, like TIGIT, and they sometimes may not even have an effect at all in the advanced cancer setting. So, we'll see what the HARMONY phase 3 trial, that's the Regeneron cemiplimab/fianlimab versus pembrolizumab control with cemiplimab with fianlimab at two different doses, we'll see how that reads out. But certainly, as you've said, LAG-3 does not, unfortunately, appear to have an impact in the adjuvant setting. So let's move on to LBA9501. This is the primary analysis of EORTC-2139-MG or the Columbus-AD trial. This was a randomized trial of encorafenib and binimetinib, which we will abbreviate as enco-bini going forward, compared to placebo in high-risk stage II setting in melanoma in patients with BRAF V600E or K mutant disease. So Jason, you know, you happen to know one or two things about the resected stage II setting, so maybe contextualize the stage II setting for us based on the trials that you've led, KEYNOTE-716, as well as CheckMate-76K, set us up to talk about Columbus-AD. Dr. Jason Luke: Thanks for that introduction, and certainly stage II disease has been something I've worked a lot on. The rationale for that has been that building off of the activity of anti–PD-1 in metastatic melanoma and then seeing the activity in stage III, like we just talked about, it was a curious circumstance that dating back about 7 to 8 years ago, there was no availability to use anti–PD-1 for high-risk stage II patients, even though the risk of recurrence and death from melanoma in the context of stage IIB and IIC melanoma is in fact similar or actually higher than in stage IIIA or IIIB, where anti–PD-1 was approved. And in that context, a couple of different trials that you alluded to, the Keynote-716 study that I led, as well as the CheckMate 76K trial, evaluated pembrolizumab and nivolumab, respectively, showing an improvement in relapse-free and distant metastasis-free survival, and both of those agents have subsequently been approved for use in the adjuvant setting by the US FDA as well as the European Medicines Agency.  So bringing then to this abstract, throughout melanoma oncology, we've seen that the impact of anti–PD-1 immunotherapy versus BRAF and MEK-targeted therapy have had very similar outcomes on a sort of comparison basis, both in frontline metastatic and then in adjuvant setting. So it was a totally reasonable question to ask: Could we use adjuvant BRAF and MEK inhibitor therapy? And I think all of us expected the answer would be yes. As we get into the discussion of the trial, I think the unfortunate circumstance was that the timing of this clinical trial being delayed somewhat, unfortunately, made it very difficult to accrue the trial, and so we're going to have to try to read through the tea leaves sort of, based on only a partially complete data set. Dr. Diwakar Davar: So, in terms of the results, they wanted to enroll 815 patients, they only enrolled 110. The RFS and DMFS were marginally improved in the treatment arm but certainly not significantly, which is not surprising because the trial had only accrued 16% to 18% of its complete accrual. As such, we really can't abstract from the stage III COMBI-AD data to stage II patients. And certainly in this setting, one would argue that the primary treatment options certainly remain either anti–PD-1 monotherapy, either with pembrolizumab or nivolumab, based on 716 or 76K, or potentially active surveillance for the patients who are not inclined to get treated.  Can you tell us a little bit about how you foresee drug development going forward in this space because, you know, for example, with HARMONY, certainly IIC disease is a part of HARMONY. We will know at least a little bit about that in this space. So what do you think about the stage IIB/C patient population? Is this a patient population in which future combinations are going to be helpful, and how would you think about where we can go forward from here? Dr. Jason Luke: It is an unfortunate circumstance that this trial could not be accrued at the pace that was necessary. I think all of us believe that the results would have been positive if they'd been able to accrue the trial. In the preliminary data set that they did disclose of that 110 patients, you know, it's clear there is a difference at a, you know, a landmark at a year. They showed a 16% difference, and that would be in line with what has been seen in stage III. And so, you know, I think it's really kind of too bad. There's really going to be no regulatory approach for this consideration. So using BRAF and MEK inhibition in stage II is not going to be part of standard practice moving into the future. To your point, though, about where will the field go? I think what we're already realizing is that in the adjuvant setting, we're really overtreating the total population. And so beyond merely staging by AJCC criteria, we need to move to biomarker selection to help inform which patients truly need the treatment. And in that regard, I don't think we've crystallized together as a field as yet, but the kinds of things that people are thinking about are the integration of molecular biomarkers like ctDNA. When it's positive, it can be very helpful, but in melanoma, we found that, unfortunately, the rates are quite low, you know, in the 10% to 15% range in the adjuvant setting. So then another consideration would be factors in the primary tumor, such as gene expression profiling or other considerations.  And so I think the future of adjuvant clinical trials will be an integration of both the standard AJCC staging system as well as some kind of overlaid molecular biomarker that helps to enrich for a higher-risk population of patients because on a high level, when you abstract out, it's just clearly the case that we're rather substantially overtreating the totality of the population, especially given that in all of our adjuvant studies to date for anti–PD-1, we have not yet shown that there's an overall survival advantage. And so some are even arguing perhaps we should even reserve treatment until patients progress. I think that's a complicated subject, and standard of care at this point is to offer adjuvant therapy, but certainly a lot more to do because many patients, you know, unfortunately, still do progress and move on to metastatic disease. Dr. Diwakar Davar: Let's transition to Abstract 2508. So we're moving on from the melanoma to the novel immunotherapy abstracts. And this is a very, very, very fascinating drug. It's IMA203. So Abstract 2508 is a phase 1 clinical update of IMA203. IMA203 is an autologous TCR-T construct targeting PRAME in patients with heavily pretreated PD-1-refractory metastatic melanoma. So Jason, in the PD-1 and CTLA-4-refractory settings, treatment options are either autologous TIL, response rate, you know, ballpark 29% to 31%, oncolytic viral therapy, RP1 with nivolumab, ORR about 30-ish percent. So new options are needed. Can you tell us a little bit about IMA203? Perhaps tell us for the audience, what is the difference between a TCR-T and traditional autologous TIL? And a little bit about this drug, IMA203, and how it distinguishes itself from the competing TIL products in the landscape. Dr. Jason Luke: I'm extremely enthusiastic about IMA203. I think that it really has transformative potential based on these results and hopefully from the phase 3 trial that's open to accrual now. So, what is IMA203? We said it's a TCR-T cell product. So what that means is that T cells are removed from a patient, and then they can be transduced through various technologies, but inserted into those T cells, we can then add a T-cell receptor that's very specific to a single antigen, and in this case, it's PRAME. So that then is contrasted quite a bit from the TIL process, which includes a surgical resection of a tumor where T cells are removed, but they're not specific necessarily to the cancer, and they're grown up in the lab and then given to the patient. They're both adoptive cell transfer products, but they're very different. One is genetically modified, and the other one is not. And so the process for generating a TCR-T cell is that patients are required to have a new biomarker that some may not be familiar with, which is HLA profiling. So the T-cell receptor requires matching to the concomitant HLA for which the peptide is bound in. And so the classic one that is used in most oncology practices is A*02:01 because approximately 48% of Caucasians have A*02:01, and the frequency of HLA in other ethnicities starts to become highly variable. But in patients who are identified to have A*02:01 genotype, we can then remove blood via leukapheresis or an apheresis product, and then insert via lentiviral transduction this T-cell receptor targeting PRAME. Patients are then brought back to the hospital where they can receive lymphodepleting chemotherapy and then receive the reinfusion of the TCR-T cells. Again, in contrast with the TIL process, however, these T cells are extremely potent, and we do not need to give high-dose interleukin-2, which is administered in the context of TIL. Given that process, we have this clinical trial in front of us now, and at ASCO, the update was from the phase 1 study, which was looking at IMA203 in an efficacy population of melanoma patients who were refractory at checkpoint blockade and actually multiple lines of therapy. So here, there were 33 patients and a response rate of approximately 50% was observed in this population of patients, notably with a duration of response approximately a year in that treatment group. And I realize that these were heavily pretreated patients who had a range of very high-risk features. And approximately half the population had uveal melanoma, which people may be aware is a generally speaking more difficult-to-treat subtype of melanoma that metastasizes to the liver, which again has been a site of resistance to cancer immunotherapy. So these results are extremely promising. To summarize them from what I said, it's easier to make TCR-T cells because we can remove blood from the patient to transduce the T cells, and we don't have to put them through surgery. We can then infuse them, and based on these results, it looks like the response rate to IMA203 is a little bit more than double what we expect from lifileucel. And then, whereas with lifileucel or TILs, we have to give high-dose IL-2, here we do not have to give high-dose IL-2. And so that's pretty promising. And a clinical trial is ongoing now called the SUPREME phase 3 clinical trial, which is hoping to validate these results in a randomized global study. Dr. Diwakar Davar: Now, one thing that I wanted to go over with you, because you know this trial particularly well, is what you think of the likelihood of success, and then we'll talk a little bit about the trial design. But in your mind, do you think that this is a trial that has got a reasonable likelihood of success, maybe even a high likelihood of success? And maybe let's contextualize that to say an alternative trial, such as, for example, the TebeAM trial, which is essentially a T-cell bispecific targeting GP100. It's being compared against SOC, investigator's choice control, also in a similarly heavily pretreated patient population. Dr. Jason Luke: So both trials, I think, have a strong chance of success. They are very different kinds of agents. And so the CD3 bispecific that you referred to, tebentafusp, likely has an effect of delaying progression, which in patients with advanced disease could have a value that might manifest as overall survival. With TCR-T cells, by contrast, we see a very high response rate with some of the patients going into very durable long-term benefit. And so I do think that the SUPREME clinical trial has a very high chance of success. It will be the first clinical trial in solid tumor oncology randomizing patients to receive a cell therapy as compared with a standard of care. And within that standard of care control arm, TILs are allowed as a treatment. And so it will also be the first study that will compare TCR-T cells against TILs in a randomized phase 3. But going back to the data that we've seen in the phase 1 trial, what we observe is that the duration of response is really connected to the quality of the response, meaning if you have more than a 50% tumor shrinkage, those patients do very, very well. But even in patients who have less than 50% tumor shrinkage, the median progression-free survival right now is about 4.5 months. And again, as we think about trial design, standard of care options for patients who are in this situation are unfortunately very bad. And the progression-free survival in that population is probably more like 2 months. So this is a trial that has a very high likelihood of being positive because the possibility of long-term response is there, but even for patients who don't get a durable response, they're likely going to benefit more than they would have based on standard chemotherapy or retreatment with an anti–PD-1 agent. Dr. Diwakar Davar: Really, a very important trial to enroll, a trial that is first in many ways. First of a new generation of TCR-T agents, first trial to look at cell therapy in the control arm, a new standard of efficacy, but potentially also if this trial is successful, it will also be a new standard of trial conduct, a new kind of trial, of a set of trials that will be done in the second-line immunotherapy-refractory space. So let's pivot to the last trial that we were going to discuss, which was Abstract 2501. Abstract 2501 is a first-in-human phase 1/2 trial evaluating BNT142, which is the first-in-class mRNA-encoded bispecific targeting Claudin-6 and CD3 in patients with Claudin-positive tumors. We'll talk a little bit about this, but maybe let's start by talking a little bit about Claudin-6. So Claudin-6 is a very interesting new target. It's a target that's highly expressed in GI and ovarian tumors. There are a whole plethora of Claudin-6-targeting agents, including T-cell bispecifics and Claudin-6-directed CAR-Ts that are being developed. But BNT142 is novel. It's a novel lipid nanoparticle LNP-encapsulated mRNA. The mRNA encodes an anti–Claudin-6 CD3 bispecific termed RiboMAB-021. And it then is administered to the patient. The BNT142-encoding mRNA LNPs are taken up by the liver and translated into the active drug. So Jason, tell us a little bit about this agent. Why you think it's novel, if you think it's novel, and let's talk a little bit then about the results. Dr. Jason Luke: So I certainly think this is a novel agent, and I think this is just the first of what will probably become a new paradigm in oncology drug development. And so you alluded to this, but just to rehash it quickly, the drug is encoded as genetic information that's placed in the lipid nanoparticle and then is infused into the patient. And after the lipid nanoparticles are taken up by the liver, which is the most common place that LNPs are usually taken up, that genetic material in the mRNA starts to be translated into the actual protein, and that protein is the drug. So this is in vivo generation, so the patient is making their own drug inside their body. I think it's a really, really interesting approach. So for any drug that could be encoded as a genetic sequence, and in this case, it's a bispecific, as you mentioned, CD3-Claudin-6 engager, this could have a tremendous impact on how we think about pharmacology and novel drug development moving into the future in oncology. So I think it's an extremely interesting drug, the like of which we'll probably see only more moving forward. Dr. Diwakar Davar: Let's maybe briefly talk about the results. You know, the patient population was heavily pretreated, 65 or so patients, mostly ovarian cancer. Two-thirds of the patients were ovarian cancer, the rest were germ cell and lung cancer patients. But let's talk a little bit about the efficacy. The disease control rate was about 58% in the phase 1 population as a whole, but 75% in the ovarian patient population. Now tell us a little bit about the interesting things about the drug in terms of the pharmacokinetics, and also then maybe we can pivot to the clinical activity by dose level. Dr. Jason Luke: Well, so they did present in their presentation at ASCO a proportionality showing that as higher doses were administered, that greater amounts of the drug were being made inside the patient. And so that's an interesting observation, and it's an important one, right? Suggesting that the pharmacology that we classically think of by administering drugs by IV, for example, would still be in play. And that did translate into some level of efficacy, particularly at the higher dose levels. Now, the caveat that I'll make a note of is that disease control rate is an endpoint that I think we have to be careful about because what that really means is sometimes a little bit unclear. Sometimes patients have slowly growing tumors and so on and so forth. And the clinical relevance of disease control, if it doesn't last at least 6 months, I think is probably pretty questionable. So I think these are extremely interesting data, and there's some preliminary sense that getting the dose up is going to matter because the treatment responses were mostly observed at the highest dose levels. There's also a caveat, however, that across the field of CD3 bispecific molecules like this, there's been quite a bit of heterogeneity in terms of the response rate, with some of them only really generating stable disease responses and other ones having more robust responses. And so I think this is a really interesting initial foray into this space. My best understanding is this molecule is not moving forward further after this, but I think that this really does set it up to be able to chase after multiple different drug targets on a CD3 bispecific backbone, both in ovarian cancer, but then basically across all of oncology. Dr. Diwakar Davar: Perfect. This is a very new sort of exciting arena where we're going to be looking at, in many ways, these programmable constructs, whether we're looking at in vivo-generated, in this case, a T-cell bispecific, but we've also got newer drugs where we are essentially giving drugs where people are generating in vivo CAR T, and also potentially even in vivo TCR-T. But certainly lots of new excitement around this entire class of drugs. And so, what we'd like to do at this point in time is switch to essentially the fact that we've got a very, very exciting set of data at ASCO 2025. You've heard from Dr. Luke regarding the advances in both early drug development but also in advanced cutaneous melanoma. And Jason, as always, thank you so much for sharing your very valuable and great, fantastic insights with us on the ASCO Daily News Podcast. Dr. Jason Luke: Well, thanks again for the opportunity. Dr. Diwakar Davar: And thank you to our listeners for taking your time to listen today. You will find the links to the abstracts that we discussed today in the transcript of this episode. And finally, if you value the insights that you hear on the ASCO Daily News Podcast, please take a moment to rate, review, and subscribe wherever you get your podcasts. Disclaimer: The purpose of this podcast is to educate and to inform. This is not a substitute for professional medical care and is not intended for use in the diagnosis or treatment of individual conditions. Guests on this podcast express their own opinions, experience, and conclusions. Guest statements on the podcast do not express the opinions of ASCO. The mention of any product, service, organization, activity, or therapy should not be construed as an ASCO endorsement. Follow today's speakers:    Dr. Diwakar Davar    @diwakardavar    Dr. Jason Luke @jasonlukemd Follow ASCO on social media:     @ASCO on Twitter       ASCO on Bluesky   ASCO on Facebook       ASCO on LinkedIn   Disclosures:     Dr. Diwakar Davar:      Honoraria: Merck, Tesaro, Array BioPharma, Immunocore, Instil Bio, Vedanta Biosciences     Consulting or Advisory Role: Instil Bio, Vedanta Biosciences     Consulting or Advisory Role (Immediate family member): Shionogi     Research Funding: Merck, Checkmate Pharmaceuticals, CellSight Technologies, GSK, Merck, Arvus Biosciences, Arcus Biosciences     Research Funding (Inst.): Zucero Therapeutics     Patents, Royalties, Other Intellectual Property: Application No.: 63/124,231 Title: COMPOSITIONS AND METHODS FOR TREATING CANCER Applicant: University of Pittsburgh–Of the Commonwealth System of Higher Education Inventors: Diwakar Davar Filing Date: December 11, 2020 Country: United States MCC Reference: 10504-059PV1 Your Reference: 05545; and Application No.: 63/208,719 Enteric Microbiotype Signatures of Immune-related Adverse Events and Response in Relation to Anti-PD-1 Immunotherapy     Dr. Jason Luke:     Stock and Other Ownership Interests: Actym Therapeutics, Mavu Pharmaceutical, Pyxis, Alphamab Oncology, Tempest Therapeutics, Kanaph Therapeutics, Onc.AI, Arch Oncology, Stipe, NeoTX     Consulting or Advisory Role: Bristol-Myers Squibb, Merck, EMD Serono, Novartis, 7 Hills Pharma, Janssen, Reflexion Medical, Tempest Therapeutics, Alphamab Oncology, Spring Bank, Abbvie, Astellas Pharma, Bayer, Incyte, Mersana, Partner Therapeutics, Synlogic, Eisai, Werewolf, Ribon Therapeutics, Checkmate Pharmaceuticals, CStone Pharmaceuticals, Nektar, Regeneron, Rubius, Tesaro, Xilio, Xencor, Alnylam, Crown Bioscience, Flame Biosciences, Genentech, Kadmon, KSQ Therapeutics, Immunocore, Inzen, Pfizer, Silicon Therapeutics, TRex Bio, Bright Peak, Onc.AI, STipe, Codiak Biosciences, Day One Therapeutics, Endeavor, Gilead Sciences, Hotspot Therapeutics, SERVIER, STINGthera, Synthekine     Research Funding (Inst.): Merck , Bristol-Myers Squibb, Incyte, Corvus Pharmaceuticals, Abbvie, Macrogenics, Xencor, Array BioPharma, Agios, Astellas Pharma , EMD Serono, Immatics, Kadmon, Moderna Therapeutics, Nektar, Spring bank, Trishula, KAHR Medical, Fstar, Genmab, Ikena Oncology, Numab, Replimmune, Rubius Therapeutics, Synlogic, Takeda, Tizona Therapeutics, Inc., BioNTech AG, Scholar Rock, Next Cure     Patents, Royalties, Other Intellectual Property: Serial #15/612,657 (Cancer Immunotherapy), and Serial #PCT/US18/36052 (Microbiome Biomarkers for Anti-PD-1/PD-L1 Responsiveness: Diagnostic, Prognostic and Therapeutic Uses Thereof)     Travel, Accommodations, Expenses: Bristol-Myers Squibb, Array BioPharma, EMD Serono, Janssen, Merck, Novartis, Reflexion Medical, Mersana, Pyxis, Xilio

For anyone who's been hoping for a surprise to boost markets recently, good news came from an unexpected place earlier this month. After months and months of delay, and multiple anonymous sources suggesting that biofuel levels were set to disappoint the industry, the actual numbers announced by EPA stunned watchers with a proposed 2 billion gallon jump up in the biomass based diesel requirements. And that was just the start of the upside news on renewable fuels.To help us follow the twists and turns of the latest updates, DTN Staff reporter Todd Neeley joins us today with analysis on the EPA's proposal, as well as news from the courts, state policy, and beyond. We'll dig into the RFS ethanol levels as set in the proposal, as well as what still might be ahead this summer for E15, especially with recent positive changes coming out of California. We'll also get an update on the state of the RINs market and a legal step forward for small refinery waivers. We'll also venture beyond the fuels space to hear news about the Make America Healthy Again, or MAHA, report, and get a breakdown on how ag has and hasn't been included, and what the next steps may be. Finally, we'll hear more on some emerging lawsuits around discrimination, glyphosate liability.

Tracey Olson, COO at Guardian Energy Management and NDCGA Industry Representative, discusses the EPA's announcement of proposed RFS volume obligations for 2026 and 2027.See omnystudio.com/listener for privacy information.

Raidījumā Piespēle pirmo reizi pēc formāta maiņas runājam par ātrumlaivu sportu. Nesen par Eiropas čempionu F-2 klasē kļuva Latvijas labākais ātrumlaivu sportists Ņikita Lijcs. Viņš stāsta par šī sporta veida popularitāti Latvijā, kā arī saviem nākotnes plāniem. Nedēļas topā: Uvis Balinskis un Floridas “Panthers” otro gadu pēc kārtas triumfē Nacionālās hokeja līgas Stenlija kausa finālsērijā, šogad sešās spēlēs uzvar Edmontonas “Oilers”; Amerikas Hokeja līgas finālsērijā būs vajadzīgas vismaz sešas spēles - Artūram Šilovam un Ebotsfordas “Canucks” pagaidām nav izdevies iegūt Kaldera kausu, bet sērijā 3-2 pret Sanda Vilmaņa pārstāvēto Šārlotes “Checkers”; Kitija Laksa rezultatīvi turpina spēlēt Sieviešu Nacionālajā basketbola asociācijā, bet Fīniksas “Mercury” izvirzās līgas vadošajās pozīcijās; Latvijas futbola virslīgas otrais aplis noslēdzas ar Rīgas derbiju, tajā šoreiz pēc ilgāka pārtraukuma noskaidro uzvarētāju - kopvērtējuma līdere “Riga” ar 3:1 uzveic RFS un palielina pārsvaru skrējienā pēc čempiontitula.

In this week's episode, we explore the USDA's new solution to combat the New World Screwworm, break down the EPA's latest Renewable Fuel Standard and sit down with a soybean crusher who shares how he got his start in the biodiesel industry. In the news, President Trump halts immigration raids on farms and food plants after pushback from ag groups. An Indiana equipment dealer faces 17 felony charges in a $750,000 farm fraud case. We broke down the EPA's new Renewable Fuel Standard. Plus, China reopens trade to over 100 U.S. meat plants, fertilizer markets tighten amid global conflict and Capitol Hill cools off with the dairy industry's annual ice cream celebration. This week's interview shares some of the uncertainty leading up to the Environmental Protection Agency's recent guidance on the Renewable Fuel Standard (RFS) released this past week. Michelle Stangler visited Incobrasa, a soybean crush and biodiesel facility in Illinois, where she spoke with Quality Control Manager Kerry Fogarty during a tour organized by the Clean Fuels Alliance America. Fogarty shared insights on the history of the biodiesel tax incentive, the impact of recent plant shutdowns and what the RFS means to facilities like Incobrasa. He also discussed the uncertainty surrounding expansion projects at the facility, along with concerns about the recent cutbacks to the USAID program. The conversation highlighted both challenges and opportunities for soybean-based fuels moving forward. Stay connected with us for more agriculture content on Instagram, TikTok, Facebook, and YouTube, along with our weekly videos!

This Farm Talk segment features Tracey Olson, COO at Guardian Energy Management and North Dakota Corn Growers Association Industry Representative. Olson discusses the recent EPA announcement of proposed RFS volume obligations for 2026 and 2027. See omnystudio.com/listener for privacy information.

Steven Johnson, retired Iowa State Extension farm management specialist; Ken Ericksen, Polaris Analytics and Consulting, trends in ag trade and barge transport

There is mixed trade to begin the week with continued support for beans and soybean oil following the EPA announcements on the RFS. Greg McBride of Allendale joins Mark Magnuson for today's opening market podcast.

Von Christine Mayrhofer. Von 13. bis 15. Mai sind Österreichs Studierende zur Wahl aufgerufen. Was versprechen und fordern die elf antretenden Listen und Fraktionen? Und wieso ist die Wahlbeteiligung bei ÖH-Wahlen traditionell so niedrig?

A bi-partisan letter from U.S. Senators was sent to EPA urging the agency to raise RFS volumes. Paul Winters, director, public affairs and federal communications for Clean Fuels Alliance America, joins us to discuss the details. This week's Farmer Forum features Tim Burrack of Iowa and Sherman Newlin of Illinois.See omnystudio.com/listener for privacy information.

On this episode of Agriculture Today, we'll learn about some reports that the USDA will once again be distributing, takeaways from the most recent USDA supply and demand report, continued debate over the RFS, and some comments from the U.S. EPA administrator on the review of crop protection tools.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Rīgā pārspējot Amsterdamas "Ajax", RFS kļuva par pirmo Latvijas futbola klubu, kas izcīnījis uzvaru Eirokausu pamatturnīrā. Astoņās spēlēs iegūti pieci punkti, ierindojoties 32. vietā. Lai noskaidrotu, kurš futbolists visvairāk pacēla savu vērtību, ko starts UEFA Eiropas līgā nesa Latvijai un kas tika izdarīts nepareizi, sagaidot "Ajax" ultras, Ulvis Brože studijā aicināja Sportacentrs.com futbola cilvēku Agri Suveizdu un "Go3" futbola komentētāju Arkādiju Birjuku. Sportacentrs.com podkāsts Ārpus kadra – katru trešdienas vakaru kanālā TV4, portālā Sportacentrs.com un visās populārākajās audio straumēšanas platformās. Ārpus kadra 2025. gadā uz priekšu dzen oficiālais KTM un MERIDA velosipēdu pārstāvis Latvijā AstraVelo, bet podkāstam veldzi nodrošina Vytautas minerālūdens

On Tuesday's AOA, we kick off the show with an update on 45Z, RFS and more with Kurk Kovarik from Clean Fuels Alliance America. Then we continue our coverage of the AgMarket.net “Farming for Profit, Not Price” conference and have a conversation with Dan Basse from AgResource Company. Then, we sit down with Matt Bennett from AgMarket.net in Segment Three and close the show with a cattle market outlook from Ross Baldwin of AgMarket.net.  

"Lufthansa" kā stratēģiskais investors palielinās "airBaltic" vērtību; potenciālajiem investoriem interesē uzņēmuma nākotnes peļņa. Ārpolitikas debates: nepieciešams atbalstīt Ukrainu un stiprināt savu aizsardzību. Latvijas Banka aicina hipotekāro kredītu ņēmējus vairāk izmantot pārkreditēšanās iespējas, lai nepārmaksātu par šiem aizdevumiem. Latvijas čempioni futbolā RFS aizvadīs pēdējo maču UEFA Eiropas līgas pamatturnīrā jeb līgas fāzē. Prezentē pirmo elektrovilcienu, kurš aprīkots ar velosipēdu pārvadāšanai paredzētajiem stiprinājumiem. Līdz ar pilna apmēra iebrukumu Krievija tās okupētajās teritorijās Ukrainā aktivizējusi ukraiņu bērnu apmācību militārām iemaņām, tādejādi gatavojot mobilizācijas rezerves Krievijas armijai.

De griepgolf heeft ook de Pantelic Podcast bereikt, maar Bart en Jan zorgen online toch gewoon voor een nieuwe Pantelic Podcast. En dat is maar goed ook, want het is de week van de waarheid voor Ajax. Met Galatasaray, maar vooral De Klassieker aankomende zondag staat er nogal wat op het programma. Ze bespreken de wedstrijden voor, maar ook zeker de andere manier waarop het de week van de waarheid is. Namelijk die voor Alex Kroes. Het is nog still op de transfermarkt. En Kroes is na vijf maanden terug bij af, want Carlos Forbs lijkt de nieuwe (oude) linksbuiten te gaan worden. Hij moet nu echt aan de bak met de naderende transfer deadline!(00:00) Intro(01:20) Nog even RFS(10:10) Druk op Kroes neemt toe(25:55) Uitgaand gebeurt er wel wat(31:28) Interesse in Cedric Hatenboer(34:08) Speculaties rond Brobbey(39:46) Galatasaray zonder Ziyech in de Arena(43:18) De Klassieker(52:32) Het Pantelic Plakboek(56:32) Jong Ajax stelt teleurZie het privacybeleid op https://art19.com/privacy en de privacyverklaring van Californië op https://art19.com/privacy#do-not-sell-my-info.

Our first Europa League match-day of the year! The week kicked off in dramatic fashion around Istanbul - Kyiv stunning Galatasaray on Tuesday with a comeback draw for their first point of the campaign, then Besiktas taking it to Athletic Club on Wednesday in Ole Gunnar Solskjær's first game in charge. Thursday featured a slate of big clubs going head-to-head, where Sociedad, Roma, Fenerbahce failed to show up, pushing them dangerously close to missing out on qualification. Elsewhere, Tottenham and Hoffenheim remain maddeningly inconsistent, and RFS pulls off their first ever Europa League win against the mighty Ajax. We also turn to January 30's games - the final match-day of the inaugural League Phase - and discuss all the important fixtures and table scenarios. Cheers Dino Toppmöller!

15min tinklalaidėje apie Lietuvos ir pasaulio futbolą „Skrieja kamuolys“ – žaidimų konsolės, geriausiųjų rinkimai, Vilniaus „Riterių“ investuotojai, „draugiškos“ Matijaus Remeikio rungtynės su Rusijos klubu, brangiausia futbolininkė istorijoje, „Bayern“ paslydimas Roterdame, „El Cashico“, Čempionų lygos formatas, nauja geriausia komanda pasaulyje, A.Chusanovo kliurkos ir kitoks „Manchester City“ žaidimas, vargo vakarienė „Tottenham“ bei „Manchester United“ stovyklose, Mariaus kelionė į Rygą, kur RFS paguldė „Ajax“, ispanų, vokiečių ir italų lygos. Prie mikrofonų – 15min sporto žurnalistai Aurimas Tamulionis ir Marius Bagdonas bei „Go3“ komentatoriai Rytis Vyšniauskas ir Karolis Dudėnas. 00:00 Konsolės ir Mariaus prisiminimas iš vaikystės 07:44 Geriausi Lietuvos metų futbolininkai 12:08 Kas tie Vilniaus „Riterių“ investuotojai? 18:24 Lietuvos klubų kontroliniai mūšiai 32:13 Gineitis turės dar vieną konkurentą? 33:31 Kiti lietuviai svetur ir Remeikio mačas su rusais 37:07 Salės futbolas ir brangiausia futbolininkė istorijoje 40:10 „Bayern“ sumuštas Roterdame, „Man City“ – Paryžiuje 51:09 Kaip jums naujasis Čempionų lygos formatas? 1:06:10 Istorinė savaitė Lietuvos teisėjams 1:08:37 Geriausia komanda pasaulyje ir „Liverpool“ 1:20:59 Chusavono kliurkos, Pepas ir kitoks „Man City“ 1:32:43 „Tottenham“ ir „Man United“ vargas 1:39:51 RFS paguldė „Ajax“ – Mariaus įspūdžiai iš Rygos 1:45:42 K.Mbappe hat-trickas ir G.Neville‘o šmėkla 1:53:50 Į gynybą atsitraukęs „Bayer“ ir pramušęs H.Kane‘as 2:02:44 „Napoli“ aukštaūgiai ir cirkai Milane

Rechtstreeks uit het vliegtuig vanuit Letland probeert Arco met Freek de kater van de 1-0 nederlaag van Ajax bij RFS weg te spoelen in een nieuwe aflevering van de Pak Schaal Podcast. Hoe was het in Riga? Ook de concrete interesse in Brian Brobbey van West Ham United pakken we mee.Zie het privacybeleid op https://art19.com/privacy en de privacyverklaring van Californië op https://art19.com/privacy#do-not-sell-my-info.

Un poco de competiciones mainstream: qué va a pasar en la última jornada de la Champions y quién va a ser el portero del Barça en los próximos partidos. Y el underground habitual: cosas de copas portuguesas, del histórico triunfo del RFS letón, de la gran aparición del momento en la segunda española... También: Rueda de Prensa y Comunicado por el Borrado del Podcast Efímero.

Een wanvertoning van Ajax in Letland. Er werd met 1-0 van RFS verloren. Bart Obbink en Jan Verdonk spreken het na in de Wedstrijdeditie.Wedstrijdwoord niet gewonnen en toch 'Eenmalige Ajacieden' willen lezen?Bestel hem dan op: https://boekengilde.nl/boekenshop/eenmalige-ajacieden/?srsltid=AfmBOoprtZVdSRy5vaNGwUSgp1Oh3shzb7iNxw_uQ0c8rgY3lpGaH9mUZie het privacybeleid op https://art19.com/privacy en de privacyverklaring van Californië op https://art19.com/privacy#do-not-sell-my-info.

Feyenoord kwam een dag na de zege op Bayern München met duidelijkheid over de positie van de trainer. Brian Priske mag blijven bij de club uit Rotterdam. En dat na dagen van speculaties over zijn positie. In de Europa League wonnen AZ en FC Twente hun wedstrijd. Ajax verloor in Riga met 1-0 van RFS na een hele slechte wedstrijd. In de AD Voetbalpodcast bespreekt Etienne Verhoeff met Sjoerd Mossou deze zaken en Lex Lammers kijkt naar de KKD. ,,Die quotes van Dennis te Kloese zeggen niet zo veel en is gezwets in de ruimte", vertelt Mossou over het aanblijven van Priske. ,,Na grote twijfels en een crisisberaad waarbij ze dachten aan een ontslag, mag hij toch blijven. Als je de optelsom met de voors en tegens naast elkaar, vind ik het wel een logische conclusie dat Priske mag blijven. Bovendien: wat is het alternatief? Wie is er beschikbaar als vervanger?"Ook bespreken ze Europese avond in de Europa League. ,,Het was bijna een perfecte week voor de Nederlandse club in Europa en de coëfficiëntenlijst. Alleen Ajax liet het afweten in Riga. Dat was wel een afgang in de Europese geschiedenis van de club." Beluister de hele AD Voetbalpodcast nu via AD.nl, de AD App of jouw favoriete podcastplatform. Vergeet je niet te abonneren op de podcast. Dan krijg je elke dag de nieuwe show automatisch in je playlist.Support the show: https://krant.nlSee omnystudio.com/listener for privacy information.

Režisora Ginta Zilbaloža animācijas filma "Straume" kļuvusi par pirmo Latvijas filmu, kas nominēta ASV Kinoakadēmijas balvai jeb "Oskaram". Esam tikai ceļa sākumā un būs vajadzīgs laiks, lai izstrādātu stratēģiju attiecībā uz noregulējumu Ukrainā - Tā atzinis prezidents Edgars Rinkēvičs. Teju par piekto daļu pieaudzis sankciju pārkāpumu skaits. Visvairāk liedz izvest automašīnas. Turpmāk pārtikas iepakošanai vairs nevarēs izmantot uzpūstu un presētu putuplasta iepakojumu Latvijas čempioni RFS savās mājās uzņems slaveno Amsterdamas Ajax.

The roller coaster of news concerning the continuing resolution means getting the perspectives of a variety of folks concerned with U.S. agriculture. We discuss the ag economy and rural banking with Alan Hoskins, president of American Farm Mortgage & Financial Services. Robert White, senior vice president of industry relations and market development at the Renewable Fuels Association, talks about E15 and the RFS. Paul Neiffer, a.k.a. The Farm CPA, also chimes in about the status of the CR and farm aid.See omnystudio.com/listener for privacy information.

מכבי תל אביב ניצחה אמש (חמישי) 1:2 את RFS הלטבית בליגה האירופית והכניסה את עצמה לתמונת העלייה לפלייאוף של המפעל כשהיא עם שש נקודות. הצהובים שרדו דרמה מוכרת, כזו שהתרחשה רק לפני שבוע בדיוק, כאשר בדקה ה-100 הפועל חדרה השוותה אחרי פנדל שרועי משפתי הצליח להדוף. הפעם, משפתי שבעצמו גרם לפנדל, הצליח גם לקלוט את הכדור באופן סופי ולהבטיח ניצחון לצהובים, שמצד אחד יכולים לשמוח ולחגוג, אבל מצד שני חייבים להבין איך האירועים האלה קורים להם שוב (פנדל שלישי העונה אחרי הדקה ה-90). וגם: הבישולים של פטאצ׳י, השערים הקשים של נחמיאס וסטואיץ׳, הדקות האחרונות וההתנהלות של תורג׳מן, דוידה ויחזקאל, הראיון של לאזטיץ׳ ובחירת השחקנים שלו בתוך המערך שבו הוא מאמין. רז אמיר ואורן קדוש מסכמים ניצחון באירופה תמונת קאבר: רויטרסSee omnystudio.com/listener for privacy information.

On this weeks podcast, I speak with NSW Rural Fire Service Area Commander Southwestern Chief Superintendent Kelwyn White. Kelwyn commenced her service with the NSW Rural Fire Service in 2002 and, since then has worked across NSW in District, State, and Area-based roles. Kelwyn has been both a salaried officer and a volunteer during her service. Kelwyn's commitment, especially in Community Risk & Community Engagement, is held in the highest regard by her peers and the community. Kelwyn continues to be a proud advocate for engaged communities, playing a significant leadership and mentoring role in this field to NSW RFS membership and the community. Kelwyn is passionate about sharing her knowledge to help others achieve their desired outcomes, as a keen advocate for training, she gives her time to develop others. When Kelwyn commenced with the RFS, she started in administration and has worked her way through the ranks to be one of the 7 Area Commanders and, currently the only female in this role.  During this time, Kelwyn has been fortunate to see the evolution in the way women are seen and operate within the RFS and is proud to have been a part of that.  Yet knowing that, there is more to come and is proud to be in a position to support, encourage and mentor women to develop into leadership roles, or simply be the best version of themselves they can be within emergency service or their own lives. As the Area Commander for the Southwestern Area, Kelwyn is responsible for the coordinated fire-fighting arrangements across the Area, including mitigation of bushfire risks to the community through strategic organisational programs to reduce risk to the community from bushfire and other emergencies and ensuring communities are engaged, prepared and warned appropriately before and during an emergency. Presenter: Adam Blum Guest: Kelwyn White Editor: Kyle Watkins Investigative Consultant: Adam Holloway

Piedāvājam portāla Sportacentrs.com futbola apskatnieka Edmunda Novicka plašu (2h un 40min.) sarunu ar futbola kluba RFS prezidentu Artjomu Milovu.

In the wake of the elections in the US, RINS Reporter Matthew Cope and US Products Associate Editor Jason Metko play a game of "hit the brakes or hit the gas" to discuss some of the potential effects on the biofuels industry - particularly important to the Renewable Fuel Standard (RFS) and road fuels - under a second Donald Trump administration.  Listen to find out if it's "hit the brakes" or "hit the gas" as we address issues including: Should we expect Small Refinery Exemptions (SREs) to return under the new Trump administration? Trump's pick to lead the Environmental Protection Agency (EPA), Lee Zeldin, previously backed a bill to eliminate the RFS. Would he do that now? Trump has expressed the desire to get rid of electric vehicle (EV) subsidies. However, with Elon Musk operating an EV company, will he push Trump for more incentives? Biden took a less favourable approach towards E15. Will it be different with Trump's return?

Một cuộc tàn sát chết người ở miền trung Sudan do lực lượng bán quân sự RFS thực hiện đã khiến ít nhất 124 người thiệt mạng và hàng chục người dân địa phương bị thương và phải di tản. SBS News đã nói chuyện với một phụ nữ Úc gốc Sudan ở Sydney, người có các thành viên trong gia đình đã thiệt mạng, bị thương và phải di tản trong các cuộc tấn công, trong khi người anh trai 27 tuổi Ibrahim của cô vẫn mất tích.

This week, the leader of Sudan's Rapid Support Forces (RSF) militia accused Egypt of supporting its opponent, the Sudanese military. Lieutenant General Mohamed Hamdan Dagalo, also known as Hemetti, said in a video message that the development marks an escalation of the conflict. Egypt has denied the accusations. Hussein Shingrai is the foreign affairs secretary of the People's Democratic Party of Sudan. He says Sudan as a sovereign country has the right to buy weapons from wherever it wants. Shingrai tells VOA's James Butty, Hemetti may be trying to blame his apparent defeat on other countries

36 games games in the Europa and Conference Leagues have come and gone, and we have a LOT to talk about! In the Europa, we had a thriller in Porto, smaller clubs getting huge upset results ( RFS (!), Elfsborg, Twente, Anderlecht), bigger clubs struggling (Galatasaray, Fenerbahce, Roma, Sociedad), and Tottenham youngsters stormed the gates in Hungary. Meanwhile in the Conference, Chelsea continued their scintillating form, Fiorentina did Fiorentina stuff, Betis fell in Poland, and Cercle Brugge ran riot on St. Gallen. Plus, we discuss the proposed changes to the Welsh Cup. All that and more on this week's show! Cheers, Oscar Hiljemark (P.S. - Stop being so handsome)!

Michelle has over 20 years of experience in Financial Services and her main goal is to always focus on her client's long-term financial planning strategy to optimize retirement income.She prides herself on analyzing a financial situation, finding any potential issues, and creating adequate solutions to ensure her clients' prosperous future. With her extensive insurance and planning experience, Michelle adds great knowledge to the already specialized team at RFS.She has worked in various capacities in the financial industry from being part of top producer teams to teaching new financial advisors through agency leadership. Michelle's passion is to help educate consumers by taking complex financial strategies and explaining them in an easy way to understand the concept. Michelle is originally from Pittsburgh, PA, and a graduate of Penn State University in Business.She now resides in Boynton Beach, FL with her husband Rob, their two daughters Olivia and London, and their three pets. When Michelle isn't working with RFS's clients or spending time with her family, she is likely exercising or on her Peloton, competing her way to the top of the leaderboard. Michelle has always loved sports as she grew up playing Basketball, Volleyball, and Softball. While living in Pittsburgh, she became part of Steeler Nation, and that devotion has carried with her to South Florida.Michelle joined Rosenzweig Financial Services in October 2021 as Vice President, specializing in the professional marketplace.Learn more: https://www.rfsny.com/Registered representative of, and securities and investment advisory services offered through Hornor, Townsend & Kent, LLC (HTK), Registered Investment Adviser, Member FINRA/SIPC, 1 North Federal Hwy, Suite 201, Boca Raton, FL 33432. 561-314-3100, http://www.htk.com. HTK is a wholly-owned subsidiary of The Penn Mutual Life Insurance Company. Rosenzweig Financial Services is unaffiliated with HTK. HTK does not offer tax or legal advice. Always consult a qualified adviser regarding your individual circumstances.Retirement Income Authority is not affiliated with HTKInfluential Entrepreneurs with Mike Saundershttps://businessinnovatorsradio.com/influential-entrepreneurs-with-mike-saunders/Source: https://businessinnovatorsradio.com/interview-w-michelle-boyce-ricp-vp-w-rosenzweig-financial-services-discussing-the-power-of-tax-free-income

Michelle has over 20 years of experience in Financial Services and her main goal is to always focus on her client's long-term financial planning strategy to optimize retirement income.She prides herself on analyzing a financial situation, finding any potential issues, and creating adequate solutions to ensure her clients' prosperous future. With her extensive insurance and planning experience, Michelle adds great knowledge to the already specialized team at RFS.She has worked in various capacities in the financial industry from being part of top producer teams to teaching new financial advisors through agency leadership. Michelle's passion is to help educate consumers by taking complex financial strategies and explaining them in an easy way to understand the concept. Michelle is originally from Pittsburgh, PA, and a graduate of Penn State University in Business.She now resides in Boynton Beach, FL with her husband Rob, their two daughters Olivia and London, and their three pets. When Michelle isn't working with RFS's clients or spending time with her family, she is likely exercising or on her Peloton, competing her way to the top of the leaderboard. Michelle has always loved sports as she grew up playing Basketball, Volleyball, and Softball. While living in Pittsburgh, she became part of Steeler Nation, and that devotion has carried with her to South Florida.Michelle joined Rosenzweig Financial Services in October 2021 as Vice President, specializing in the professional marketplace.Learn more: https://www.rfsny.com/Registered representative of, and securities and investment advisory services offered through Hornor, Townsend & Kent, LLC (HTK), Registered Investment Adviser, Member FINRA/SIPC, 1 North Federal Hwy, Suite 201, Boca Raton, FL 33432. 561-314-3100, http://www.htk.com. HTK is a wholly-owned subsidiary of The Penn Mutual Life Insurance Company. Rosenzweig Financial Services is unaffiliated with HTK. HTK does not offer tax or legal advice. Always consult a qualified adviser regarding your individual circumstances.Retirement Income Authority is not affiliated with HTKInfluential Entrepreneurs with Mike Saundershttps://businessinnovatorsradio.com/influential-entrepreneurs-with-mike-saunders/Source: https://businessinnovatorsradio.com/interview-w-michelle-boyce-ricp-vp-w-rosenzweig-financial-services-discussing-the-power-of-tax-free-income

Michelle has over 20 years of experience in Financial Services and her main goal is to always focus on her client's long-term financial planning strategy to optimize retirement income.She prides herself on analyzing a financial situation, finding any potential issues, and creating adequate solutions to ensure her clients' prosperous future. With her extensive insurance and planning experience, Michelle adds great knowledge to the already specialized team at RFS.She has worked in various capacities in the financial industry from being part of top producer teams to teaching new financial advisors through agency leadership. Michelle's passion is to help educate consumers by taking complex financial strategies and explaining them in an easy way to understand the concept. Michelle is originally from Pittsburgh, PA and a graduate from Penn State University in Business.She now resides in Boynton Beach, FL with her husband Rob, their two daughters Olivia andLondon, and their three pets. When Michelle isn't working with RFS's clients or spending time with her family, she is likely exercising or on her Peloton, competing her way to the top of the leaderboard. Michelle has always loved sports as she grew up playing Basketball, Volleyball, and Softball. While living in Pittsburgh, she became part of Steeler Nation and that devotion has carried with her to South Florida.Michelle joined Rosenzweig Financial Services in October 2021 as Vice President, specializing in the professional marketplace.Learn more: https://www.rfsny.com/Registered representative of, and securities and investment advisory services offered through Hornor, Townsend & Kent, LLC (HTK), Registered Investment Adviser, Member FINRA/SIPC, 1 North Federal Hwy, Suite 201, Boca Raton, FL 33432. 561-314-3100, http://www.htk.com. HTK is a wholly-owned subsidiary of The Penn Mutual Life Insurance Company. Rosenzweig Financial Services is unaffiliated with HTK. HTK does not offer tax or legal advice. Always consult a qualified adviser regarding your individual circumstances.Retirement Income Authority is not affiliated with HTKInfluential Entrepreneurs with Mike Saundershttps://businessinnovatorsradio.com/influential-entrepreneurs-with-mike-saunders/Source: https://businessinnovatorsradio.com/interview-w-michelle-boyce-ricp-vp-w-rosenzweig-financial-services-discussing-guaranteed-income-streams

Michelle has over 20 years of experience in Financial Services and her main goal is to always focus on her client's long-term financial planning strategy to optimize retirement income.She prides herself on analyzing a financial situation, finding any potential issues, and creating adequate solutions to ensure her clients' prosperous future. With her extensive insurance and planning experience, Michelle adds great knowledge to the already specialized team at RFS.She has worked in various capacities in the financial industry from being part of top producer teams to teaching new financial advisors through agency leadership. Michelle's passion is to help educate consumers by taking complex financial strategies and explaining them in an easy way to understand the concept. Michelle is originally from Pittsburgh, PA, and a graduate from Penn State University in Business.She now resides in Boynton Beach, FL with her husband Rob, their two daughters Olivia and London, and their three pets. When Michelle isn't working with RFS's clients or spending time with her family, she is likely exercising or on her Peloton, competing her way to the top of the leaderboard.Michelle has always loved sports as she grew up playing Basketball, Volleyball, and Softball. While living in Pittsburgh, she became part of Steeler Nation and that devotion has carried with her to South Florida.Michelle joined Rosenzweig Financial Services in October 2021 as Vice President, specializing in the professional marketplace.Learn more: https://www.rfsny.com/Registered representative of, and securities and investment advisory services offered through Hornor, Townsend & Kent, LLC (HTK), Registered Investment Adviser, Member FINRA/SIPC, 1 North Federal Hwy, Suite 201, Boca Raton, FL 33432. 561-314-3100, http://www.htk.com. HTK is a wholly-owned subsidiary of The Penn Mutual Life Insurance Company. Rosenzweig Financial Services is unaffiliated with HTK. HTK does not offer tax or legal advice. Always consult a qualified adviser regarding your individual circumstances.Retirement Income Authority is not affiliated with HTKInfluential Entrepreneurs with Mike Saundershttps://businessinnovatorsradio.com/influential-entrepreneurs-with-mike-saunders/Source: https://businessinnovatorsradio.com/interview-w-michelle-boyce-ricp-vp-w-rosenzweig-financial-services-discussing-qualified-funds-how-is-too-much

Michelle has over 20 years of experience in Financial Services and her main goal is to always focus on her client's long-term financial planning strategy to optimize retirement income.She prides herself on analyzing a financial situation, finding any potential issues, and creating adequate solutions to ensure her clients' prosperous future. With her extensive insurance and planning experience, Michelle adds great knowledge to the already specialized team at RFS.She has worked in various capacities in the financial industry from being part of top producer teams to teaching new financial advisors through agency leadership. Michelle's passion is to help educate consumers by taking complex financial strategies and explaining them in an easy way to understand the concept. Michelle is originally from Pittsburgh, PA and a graduate from Penn State University in Business.She now resides in Boynton Beach, FL with her husband Rob, their two daughters Olivia andLondon, and their three pets. When Michelle isn't working with RFS's clients or spending time with her family, she is likely exercising or on her Peloton, competing her way to the top of the leaderboard. Michelle has always loved sports as she grew up playing Basketball, Volleyball, and Softball. While living in Pittsburgh, she became part of Steeler Nation and that devotion has carried with her to South Florida.Michelle joined Rosenzweig Financial Services in October 2021 as Vice President, specializing in the professional marketplace.Learn more: https://www.rfsny.com/Registered representative of, and securities and investment advisory services offered through Hornor, Townsend & Kent, LLC (HTK), Registered Investment Adviser, Member FINRA/SIPC, 1 North Federal Hwy, Suite 201, Boca Raton, FL 33432. 561-314-3100, http://www.htk.com. HTK is a wholly-owned subsidiary of The Penn Mutual Life Insurance Company. Rosenzweig Financial Services is unaffiliated with HTK. HTK does not offer tax or legal advice. Always consult a qualified adviser regarding your individual circumstances.Retirement Income Authority is not affiliated with HTKInfluential Entrepreneurs with Mike Saundershttps://businessinnovatorsradio.com/influential-entrepreneurs-with-mike-saunders/Source: https://businessinnovatorsradio.com/interview-w-michelle-boyce-ricp-vp-w-rosenzweig-financial-services-discussing-guaranteed-income-streams

Michelle has over 20 years of experience in Financial Services and her main goal is to always focus on her client's long-term financial planning strategy to optimize retirement income.She prides herself on analyzing a financial situation, finding any potential issues, and creating adequate solutions to ensure her clients' prosperous future. With her extensive insurance and planning experience, Michelle adds great knowledge to the already specialized team at RFS.She has worked in various capacities in the financial industry from being part of top producer teams to teaching new financial advisors through agency leadership. Michelle's passion is to help educate consumers by taking complex financial strategies and explaining them in an easy way to understand the concept. Michelle is originally from Pittsburgh, PA, and a graduate from Penn State University in Business.She now resides in Boynton Beach, FL with her husband Rob, their two daughters Olivia and London, and their three pets. When Michelle isn't working with RFS's clients or spending time with her family, she is likely exercising or on her Peloton, competing her way to the top of the leaderboard.Michelle has always loved sports as she grew up playing Basketball, Volleyball, and Softball. While living in Pittsburgh, she became part of Steeler Nation and that devotion has carried with her to South Florida.Michelle joined Rosenzweig Financial Services in October 2021 as Vice President, specializing in the professional marketplace.Learn more: https://www.rfsny.com/Registered representative of, and securities and investment advisory services offered through Hornor, Townsend & Kent, LLC (HTK), Registered Investment Adviser, Member FINRA/SIPC, 1 North Federal Hwy, Suite 201, Boca Raton, FL 33432. 561-314-3100, http://www.htk.com. HTK is a wholly-owned subsidiary of The Penn Mutual Life Insurance Company. Rosenzweig Financial Services is unaffiliated with HTK. HTK does not offer tax or legal advice. Always consult a qualified adviser regarding your individual circumstances.Retirement Income Authority is not affiliated with HTKInfluential Entrepreneurs with Mike Saundershttps://businessinnovatorsradio.com/influential-entrepreneurs-with-mike-saunders/Source: https://businessinnovatorsradio.com/interview-w-michelle-boyce-ricp-vp-w-rosenzweig-financial-services-discussing-qualified-funds-how-is-too-much

A Gallifrey One guest announcement tops the RFS headlines as Jenna Coleman aka Clara Oswald is set to arrive in Los Angeles this upcoming February! Plus Russell T Davies is in the latest SFX to explain how TV works to you nerds, so what better time for the Three Who Rule to add their uninformed insights to the pile? An Emperor Davros dolly is on the way from B&M, Ncuti Gatwa's theatrical spectacular The Importance of Being Earnest heads for cinema screens and more, before a Classic Series Commentary on the penultimate episode of both “Planet of the Spiders” and the Jon Pertwee era!  Links: Support Radio Free Skaro on Patreon Jenna Coleman announced as guest of Gallifrey One RTD says Season 3 renewal won't come until after Season 2 airs BFI redux screening of The Happiness Patrol on September 29 B&M 2024 Remembrance of the Daleks – Emperor Davros B&M 2024 The History of the Daleks #18 Ncuti Gatwa's The Importance of Being Earnest getting UK cinema release Doctor Who finalists for five BAFTA Cymru Awards (aka The Welshies) Breakdown of the first scene of The Power of the Daleks Commentary: Planet of the Spiders Episode 5

Part 1 is devoted to the final round of UEFA club competition qualifying & the upcoming league phase in the three tournaments. We look at the Larne, TNS, RFS & Slovan Bratislava underdog success stories, amazing social media posts involving the Smurfs and Mr. Bean, the changed format of the three club competitions and the computerised draw, plus the best European groundhops you could make to take in the league phase action. In Part 2, we divide our time between domestic club football and the international game. A broken goal is met with the suggestion of blowtorch repair in the Icelandic top tier, Papua New Guinea's Admiralty Islands FC relocate to the mainland for six months and the international break looms large with three standout fixtures: San Marino vs. Liechtenstein, Comoros vs. Madagascar and Guyana vs. Suriname. If you don't want to wait until 18 September for our next episode, then you can join us for a bonus podcast on 11 September at patreon.com/SweeperPod. You will also be able to read our blog about the 2024 Greenlandic Football Championship, enter the draw to win a B67 shirt, become part of our growing Discord community and get exclusive content from our trip to watch San Marino take on Liechtenstein in Serravalle. RUNNING ORDER: 00:00 – Intro 03:04 – UEFA qualifiers: Upsets & underdogs 09:00 – UEFA qualifiers: Media & memes 14:13 – UEFA qualifiers: Unfamiliar formats 18:56 – UEFA qualifiers: Groundhopping guidance 24:29 – Collapsing goals in Iceland & Romania 30:56 – Papua New Guinea's relocating islanders 36:56 – San Marino & the international break 44:12 – Patreon perks & B67 shirt giveaway Editor: Ralph Foster

In this episode of the Just Schools Podcast, Jon Eckert interviews Dr. Bobby Ott, superintendent of Temple ISD and 2022 Texas Superintendent of the Year. They discuss integrating mental health services, special education needs, and innovative teaching practices. Dr. Ott highlights the importance of developing a mental health services model in schools, addressing funding and expertise limitations. He also stresses retaining specialized teachers and improving preparatory models for special education and English language learner programs Additionally, the conversation explores AI and technology's potential to transform education, advocating for proactive leadership to enhance personalized learning and prevent misuse. The Just Schools Podcast is brought to you by the Baylor Center for School Leadership. Each week, we'll talk to catalytic educators who are doing amazing work. Be encouraged. Books Mentioned: Brave New Words by Sal Khan 1000 CEOs by Andrew Davidson Connect with us: Baylor MA in School Leadership Jon Eckert LinkedIn Twitter: @eckertjon Center for School Leadership at Baylor University: @baylorcsl   Transcription: Jon Eckert: So today we're here with Bobby Ott, the superintendent of Temple ISD. He's the 2022 Superintendent of the Year for the state of Texas and a good friend of Baylor and our program. He always has a lot of wisdom to share. And so today we're going to talk a little bit about some of the challenges that he sees facing students in Temple and Texas in general and maybe just across the country because many of these issues transcend different places. Certainly they're context-specific, but broader issues. And Bobby has a pretty good handle on what's going on in Texas and has a wide network. So we're grateful to have Bobby here today. So Bobby, thanks for all you do. Just tell us a little bit about what you've been dealing with the last month or so. We'll roll in with that first and then jump into those bigger questions. But can you just update us on your world over the last month? Bobby Ott: Well, the last couple weeks for sure has been a little bit of a whirlwind, and I guess that's both figuratively and literally. But as you may know, we had three tornadoes in Temple touch down within about a 30-mile radius. And so the community really looked apocalyptic when you drove through it. Some places you couldn't drive because of debris. And of course we still had a week and a half of school left, so that caused some challenges at the 11th hour. But having a great team and a great community, number one, we were truly blessed to not have a single fatality in a natural disaster of that magnitude. So that was first and foremost. And as I shared earlier with others, to me that is certainly a divine hand being involved in that. I have never heard of a situation that had that type of catastrophe and not have a fatality. But I did send a video out, kind of a peek behind the curtain of the things we had to plan for, and we were able to make it through the last week. We were able to meet the bureaucratic requirements, which in my mind are secondary compared to the human elements of graduation, kids being in a safe environment, staff feeling safe, displaced staff having a place to be and so forth. And so now we were able to make it through that. The stress level has gone way down. And at this point, I'm just dealing with insurance adjusters and trying to figure out how to close out a budget year with deductible payments that I didn't expect to have. But anyway, we're working through it. The community is slowly getting back to normal and just blessed to have the partnerships that we do in the community and just the great hands and hearts that work together and pull together to get everybody through. Jon Eckert: No, and the video you shared was powerful because as we prepare superintendents and principals at Baylor, we try to help them anticipate every eventuality. You've taught in that. We have a number of sitting superintendents that teach in that. But until you've been through something like that, it's really hard to know what that looks like. And so I thought the video was helpful just as you went over the board and what's there. As we talk today, I want to focus in on student-centered issues that you see. Obviously, your point about the divine providence that comes in and keeps people safe in a natural disaster, that's real. There are day in, day out challenges that our kids face and resilience that they have to display and community support that they need to be successful. And so you're talking to us as we launch Cohort 8 of our EDD that's preparing superintendents. And so they're going to do three years of research on a problem of practice that they care deeply about that matters in the context they're in. And so what I'm interested in is hearing from superintendents about two or three of the biggest issues you see that need attention in the research, in data collection, but really in the practical day in and day out of how do we make life better for students? How do we do that in a way that's life-giving, that leads to flourishing, and makes sure that we're moving forward in useful ways when you're not dealing with insurance adjusters and all the budget pieces, which are real. And those have to be dealt with, otherwise you can't serve kids well. But if you were to say, "Hey, these are the two or three things that I see." That as people think about what they might research and dedicate three years of their lives to research-wise, what would come to mind as you think about that right now? Bobby Ott: And this certainly isn't in rank order, but one would be a true model of integrating. And when I say model, something that's repeatable that you could replicate in any district size, but a true model for integrating mental health services in a school district. I got to be honest with you, every year when we're sitting down as a group of superintendents, whether it's countywide or regionwide, there's always this discussion about how to truly integrate mental health services in a school system. And several districts have tried different things. They've tried some co-op services. They've tried to hire on regular counselors and get them trained in certain things and then they peel off. But there's two limitations that we find ourselves in a lot of times, and one is expertise. Rightly or wrongly, school counselors a lot of times do not have that level of expertise that we're talking about. They maybe have a general background in how to work those issues, in particular social, but the mental health pieces we find some real limitations and expertise. And then of course funding because truth be told, people that have that level of expertise make more money outside of public schools and the private sector is far more attractive and pays a lot better. So what we find ourselves doing is trying to find retirees from the private sector, people that only want to work part-time, people that really like the schedule of public schools. But people that are experts in that field could stand to make more money than the principal of the campus for sure. And so it just becomes very, very difficult. There are some very specialized skills that are required to do those kinds of things. And counselors that come out of the traditional school education track they're really equipped only to a certain line and our students are needing beyond the line. And when they try to seek outside support, a lot of times the students that have those needs do not have the resources to secure the outside support, whether it's monetary or accessibility with parents being able to get them where they need to go and so forth. So I think one, so what does that look like in terms of research? When you told me about this, I try to think about it in two lenses. One, what would be the problem? And maybe what is a approach in terms of resource or research? And I would say researching models to embed specialized counseling services, trauma-informed care, restorative practices, cognitive therapy into credentialing for counselors in their traditional track programs. Maybe therapy-specific coursework, maybe there's a way. I think we're trying to address the problem after people are certified, but I wonder if there are models that can be done between a traditional public education track in grad school in partnership with the college of psychology or behavioral sciences or something like that. And I don't know the answer to that. That's a little bit outside of my expertise. But I think there's some different directions for students there. Cohort 8 could look at maybe a preparatory model or you could look at a service model in the school system. So that would be the first one. Jon Eckert: No, that's a powerful one. And we're working in Mississippi right now with five districts because there's high levels of opioid use and abuse. And the mental health piece is such a huge part of it because you're dealing with communities that are struggling with some of that and then that is bleeding into the kids and some of the trauma that comes with that. And trying to figure out ways to put universal interventions in place that get kids making better choices that lead to thriving communities so you're less likely to make those choices is hard. But then when they've already made the choices, you need really specific interventions by highly trained people. And one of the things we've been doing in schools over the last few years is a lot of trying to fill in the gaps for people without training. And it gets really dangerous when you start trying to identify and diagnose and you have educators who are desperate for help and feel these urgent needs, but then they don't have the training. And so sometimes they can exacerbate the problem without that expertise. So I think that's tremendously insightful and needed. So what would be the next one that you have? If you were to say, "Hey, tackle this," and you said not in order, but what would be something else you would say we should be tackling? Bobby Ott: Well, the other thing that we're seeing, and this really points to special program services in particular, English language learners and special education, but those numbers are going up across the state. And there's a couple of reasons for it. I mean, I think one is generational. We're seeing that more and more in the younger generations. You're seeing more students in kinder and first with not just disabilities, but language delay and also high needs, and I'll get into that piece in a second. But the numbers go up and the funding has gone down. And so the ratios are a big problem in that mix because there are required ratios for very, very specialized programs. And when funding is going down, even the IDEA federal grant has reduced, what funds typically special education services. But the other piece is your qualifiers have expanded too. So for example, adding dyslexia to special ed has totally increased that number in every single school district. And so when those things happen, you start to pull apart the service in the program. It really starts to dilute. And so that's where we're at on that end. The other piece is RFs or residential facilities. We are really struggling because one, there's not enough residential facilities in said communities, but two, they are very liberal about denying even if they have enough beds in long and short-term placement. It literally is one of the hardest things you can possibly do to get students to qualify for a residential facility. And so what happens is those students a lot of times in schools end up becoming what I call in and outs. They're in, and then the next episode they're out. And so they never really improve educationally or anything else because we are not equipped within the school system to appropriately deliver the services those students need. And so when they're denied those services from the outside, even through referral processes, and there's a lot of complications with that, could be resources at home, it could be insurance, could be a lot of things. It could be that sometimes parents don't like to get them qualified because they'll lose some of their financial assistance. And I've run into that quite a bit too. So that's a real problem. That is a population in total that is growing, funding is not growing commensurate with the program, and specialized services are very selective for which students can be accepted and not accepted. So what's the research angle there? I mean, that's a good question. And this sounds a little bit like maybe the first one, but maybe there are different models of partnerships that we can work with students that are denied residential. I mean, there's a zone of students that we don't know how to take care of appropriately and what do we do with those students? Are there transitory programs? Are there effective practices and how we can train people to work with higher ratios or to handle students that are episodic? We are so ill-equipped in that area. And when the students don't have anywhere else to go, the default is us. And at that point, we're really not doing them a justice. We're just not. And it's heartbreaking. It's really heartbreaking. But that's something that I think would be very encouraging if there were some type of transitory model or something that can be put together. That's on the RF side. I think the other side of it, just regular special education and English language learner piece. What I find is that those are harder and harder to hire even if you do get the stipends up. I think there is an exodus of people leaving that were serving special education students. And what I hear, or what's reported to me rather through exit interviews, documented exit interviews is a lot of times it's the paperwork piece that comes with it. And this is what I don't know. It almost appears like it's a surprise. And I don't know if in prep programs there's a lot of attention given to the detail of the paperwork piece that comes with teaching in a special program because there seems to be an element of surprise when teachers are leaving and they're explaining, "Well, I didn't realize I had to do all this for RDs, I had to do all this for IEPs, I had to do all this and computer systems," and this, that and the other. And it is heavy. I mean, certainly it does carry a different weight with regard to that piece than say the regular education teacher. So that is something that I wonder at times. I don't know if that's something that's strong on the research side. I mean, obviously higher ed doesn't have the authority to minimize the bureaucratic requirements. But the time they spend with advocates, the time they spend in meetings and they walk, a lot of times they walk. And so maybe a way that we can figure out how to help school districts put together very specific teacher retention programs for special education. What does that look like? Retaining a special education and bilingual teacher that's not like retaining a general ed teacher. What does that really look like? And what are some ideas that school districts could do with helping specialized teachers with higher ratios if it comes to that? And then how can we work with students that should be in a residential facility are denied or maybe there isn't bed space or they're in for a month and they're sent back when they should have been in longer? What can we do there? So that'd be the second one. And that's probably not as succinct as the first one, but maybe there's enough directions you can go out of that. Jon Eckert: No, that's powerful and overlaps nicely with the first one. Obviously, mental health is going to weave through all of that. And so the mental health of special education teachers is also part of it. And I think you can tell people and you can prepare people say, "Hey, this is a lot of paperwork. Here's the way you're going to have to do this. These are legal contracts you're creating. This is not going to be a light lift." I think though the reality doesn't hit you until you're actually in it. Because I think most people drawn to special ed really care deeply about kids and that's what gets them... And I think it's true for teaching in general, but I think especially special ed. And then when you're hit with and you're going to have a lot more paperwork. And so you can say it, and then you live the reality and it feels different. So if you have one other challenge that you see that could use some research, some deeper thought, do you have one more in mind or anything that builds off of these two? Otherwise, we can jump to a couple other questions. Bobby Ott: I think the other one would be the general idea of pacing. There is, and this has happened probably for the last 10 years, but there seems to be this growing amount of what needs to be taught in terms of standards and the level of intricacy, which whether it's multi-step problems, high-rigor written responses, you name it. I certainly agree with testing and rigor and depth, but I disagree with the idea that the timing that teachers have to truly get students to understand things at that level and then we're adding more and more standards. To me that starts to dilute the whole entire system of public education. It becomes kind of this mile wide, inch deep versus the inverse. And so it really... I feel like as a system that we are heading toward a system of testing and minimal completion over true learning and engagement. And this is greatly because of the influence of a lot of the special interests that we're always trying to include in standards, bureaucratic systems, standard setting. And the kids really suffer greatly. And I don't know if teachers really get a handle on that piece of it because it continues to grow. So research angle, innovative teaching practices that know how to maximize time engagement, content with a group of students that are on different parts of the continuum. I know that we have things like that in prep programs, but I just think that that's something we need more and more. And I do think that we probably ought to start really considering the use of technology in a way to minimize some of the basic steps in education. And that kind of gets to the question of what opportunities do you see for educators? And I can expand on that now or wait until you comment on the third area. Jon Eckert: No, that's great. We want to jump into opportunities. Where do you see some optimistic next steps? So certainly jump right into that and then we can expand on that a little bit. Bobby Ott: I think technology use. I know AI can be received in many different ways because I've seen it firsthand. Some people turn and walk. Some people think it's a great thing. But I would love to see AI used in a way that allows the teacher to be set up in a classroom in a more intimate way with instruction and allows them to go into depth. I'm wondering if AI in tandem with a classroom teacher could create an environment where the larger nominal content can be delivered in a way in masses and the teacher can become more of, I don't want to say tutor, but someone that goes in and can either provide the enrichment or remediation in smaller groups in a classroom. I'd love to see AI shrink the classroom. And I think there's ways that that can be done. Now, I'm an administrator, so I wouldn't dare try to come up with ways without teachers being involved, but I think we almost have to get to that level. And I can't think of anything else cost-effective. I mean, you can always add more teachers in a classroom, but at some point in time that becomes a budget buster. I just wonder if there's a way to handle this through technology. So I think there are opportunities with the development of AI. I think the main thing about it is we have to lead that. It can't be something done organically because if it is students will grab a hold of that and trust me they will lead it in their own way and sometimes in an abusive way that shortchanges learning. And if that happens, then they're going to be ill prepared, number one. And number two, we're going to be spending our time as administrators doing damage control. So I think it's something we have to get ahead of. I'll tell you, we're looking as a district to have an AI conference, not this summer, but next summer, and invite school districts. We're really trying to do some things to lead the way in that. This summer is kind of a standup summer in terms of educating our staff and making sure that our network is set appropriately so we minimize abuse as much as possible. So we're doing that, but I don't see enough models out there that are something that are make take, you can grab a hold of and implement in a district. So I think there's probably some opportunity for educators there. Jon Eckert: Well, I just listened to a podcast, I haven't read the book yet, but Brave New Words by Sal Khan. He obviously with Khan Academy has influenced the learning of millions of kids, but he's super optimistic about what AI can do and creating this personalized and shrinking the classroom. And he certainly doesn't minimize the role of teachers, but it's fascinating. So I definitely need to read that. We hear about AI all the time, and you're right, you have this broad range of responses. And the challenge is going to be that is moving so rapidly that it's really hard to keep out in front. And I agree we have to. But in a world where we have been doing mile wide, inch deep for forever, William Schmidt, I think he was at Michigan State, he coined that phrase about US curriculum 30, 40 years ago. And so we've been doing this because that's what I think we do a little bit in democracies. If you can't all agree, then just put it all in. Don't narrow, just add. And so you have your special interest groups, you have all these different people that are like, "Hey, this is important." And it is important, but it can't all be important. You have to figure out ways to master things. And maybe AI can be helpful there. And I think being thoughtful about that and digging in what that means to really engage students well because Sal Khan says it, kids that are already motivated will learn really well with AI. It's the kids who are not. It's the kids with mental health issues. It's the fact that teaching is a very human endeavor. How do we make it even more human using tools? Because AI is just the newest range of tools. So it certainly doesn't replace the human being because ultimately large language models are just scraping what's on the internet. So it's consensus, not wisdom. So you certainly can learn, but if you really want to become all of who you're created to be, that requires wisdom. And so that's where the humans are there. The problem is, to your point earlier, teachers are stretched so thin and so many demands are being placed on them it's really hard to have that one-on-one interaction. It's hard to really be seen, known, and loved in a system that's not set up for that. And so if AI can help with that, I certainly am excited to see where that goes. So love that you're thinking that way. If you maybe have one other opportunity you see ahead for Temple specifically or for educators in general, what gives you some hope right now? Where do you see hopeful direction in what we're doing here in Texas? Bobby Ott: I am seeing more and more leaders leading authentically and with feeling. And I'm probably saying that in a odd way, but I see large district leaders, superintendents, and principals striking at being as personable as your smaller school. Ones are really, you don't have a choice because you're everywhere. But I see more of that and I see more of this, and I try to do it as much as... Just this shameless, this mobilizing of people to shamelessly remind others why they do it. They love children, they love staff. And as bad as the political rhetoric has been against public ed generally, I think it's mobilized educators, in particular leaders, teachers have done this night and day, leaders to say, "Hey, that doesn't characterize the entire profession. We are human. We do love our children. This is what we do. This is why we do it." And I see more of that. I really see more of that. I hear more of that when I go to conferences, when I network with superintendents. Yeah, our conversations could largely be dominated by budget and bonds and the newest innovative program and so forth. But I hear more of things like, "You know, you could get that done in your community if your community truly knows that you love their children, if your staff feels appreciated." And I think there are a lot of reasons for this effort. I think retaining people in the profession is one. But you can only go so far with money. You can only go so far with things. But positive culture, that is number one. I've always said people don't leave a job. They leave a boss because they're going to get the same job somewhere else. So this idea of how you treat people and how you demonstrate appreciation and care, I think for me, I am seeing more and more of that. I'm seeing more and more of that in the people we hire in administrative positions. I'm seeing things like that on social media. Several years ago I'd see, "Hey, we graduated 653, congratulation to the graduates." And now I'm seeing videos of a student hugging their superintendent and lifting them up off the ground and the superintendent commenting saying, "This is what it's all about." I'm just seeing more of that, whether it's small or big. And I think there's been a void of that. And I see this idea of when I get into administration, business and logistics taking over my life, that there's a real attempt to say, "It may take over my tasks, but I'm still going to put out in front my community, my students, my teachers, my school nutrition workers, and hold them up." And so that is giving me a lot of hope right now. Jon Eckert: That's great. And so these last two questions can be as short or as long as you need them to be, but on a daily basis now, given everything that you're managing, and you just highlighted a little of this, where do you find joy in the work you're doing on a daily basis? What do you go back to to maintain the joy that you seem to have in the midst of a lot of different pressures and challenges? And then the second one is is there a book that you've read in the last year that you're like, "Hey, every leader, every educator, this is a great book. This was helpful"? It doesn't even have to be in the last year. If it's something from earlier, that's great. But I always like to know those things. So where do you find your joy? What's a great book? And then we can wrap up. Bobby Ott: I find my joy in the idea that good people are still good people and they exist in the masses. So I try to make sure to connect people as much as possible to those situations. We do Mission Mondays. My entire central office every Monday is on a campus opening doors for kids that are going to school, walking in classrooms, helping to serve breakfast, do those kinds of things. I think that those kinds of things bring me joy because I see it bring them joy. I see kids get excited when there's more than the same caring adult around them, but there's others that maybe they don't even know their names right away but they know that they're in the same system that they are. It brings me joy when I see people that are normally away from kids in their job reminded of why they got into this whole profession because we put together possibilities where they are around kids. I see teachers with smile on their faces because they see a genuine care from people that aren't doing their jobs but are asking to support them. We always support people behind the scenes in our various roles, but to do it right next to someone while they're real time and to see what they're actually doing. So those kinds of things bring me joy. Just watching great educators no matter where they're at in the system making the difference in each other's lives, in students lives. So that brings me joy. And then a book that comes to my mind. I don't read a lot of educator books. I'm sorry, but I don't. I read a lot of... I do read leadership books. But there's a book called 1000s CEOs and it's by Andrew Davidson. And it really takes top CEOs and puts them in containers like visionaries, strategists, motivators, innovators, organizers, what have you. And these CEOs talk about their strategies in which the container that they're, I guess labeled in as being most effective. And so there's a lot of really good strategies in there. There was one called, a group called Startup Titans. And when we were going to implement blended learning for the first time, I wanted to hear some of the strategies of deployment from CEOs that startup companies because it was so brand new in our district. So that for me was a really, really good book. I'll warn you, if it says 1000 anything, that means it's going to be a thick book because there's a lot of pages in it. But it could be a resource. You could look at a table of contents like I did and said, "Hey, we're going to start blended learning in Temple ISD, which container would make the most sense?" Well, innovator container would make sense, a visionary one, and maybe startup titans. So I would go and read some of the CEOs strategies in those areas and then try to formulate my thoughts around deployment and so forth. So that's a book that I read and am happy to pass on. Jon Eckert: No, that's super helpful. And I think sometimes in education, we get too caught up in naval gazing, just looking at what we can learn from education. And there's a lot of fields out there that have a lot of wisdom that we can glean. And especially in the role of a superintendent where you're a politician, you're a community organizer, you're a bureaucrat, you're a manager. There's so many different hats you wear, and a human being that finds joy in the good people that you work with and the community that you serve. That's super helpful because the CEO wears many of those hats. And so I think that's great wisdom. Well, hey, Dr. Ott, thank you so much for the time. Thanks for all you do for us at Baylor, for students and staff in Temple, and then for everybody across the state of Texas. We're grateful to have you so close and your willingness to serve educators in this way. So thank you. Bobby Ott: You bet. Thank you. And I wish all the best to Cohort 8. You're entering a great program. And the one thing I would say, I don't know if this is going to them or not, but the one thing I would tell them is a lot of times when you start things like a program, people will start to ponder this idea of journey versus destination kind of thing. Which one's more important? Is it getting the doctorate? Do I try to enjoy it along the way? It's heavy, whatever it may be. And what I would pass on to you is this, anytime you find yourself being asked that question or contemplating it, the answer is neither. It should always be the company. The company is the most important thing. It's not the journey or the destination, it's the company. And so enjoy your professors, enjoy your cohort, get to know the people around you, and that will be the most important thing. And if you do that, I will tell you the journey and the destination will take care of itself. Jon Eckert: Such great advice. And that's true for everybody, not just people starting a doctoral cohort. But appreciate how you live that out, and I'm grateful that you're on the journey with us and you're part of the company that we get to keep. So thanks again. Bobby Ott: You bet. Take care.    

Kurt Kovarik, vice president, government affairs at Clean Fuels Alliance America, joins us to discuss their petitioning EPA to reconsider RFS volumes. The flooding in the Midwest and higher rivers have damaged some infrastructure, including railroads. Soy Transportation Coalition executive director Mike Steenhoek reports on the situation. And USB CEO Lucas Lentsch wraps up the month of June in this week's episode of the Soy Checkoff Check-in.See omnystudio.com/listener for privacy information.

What's all this hype around renewable diesel?  To help us dig into this topic, Matt Makinson comes back to join hosts Ryan Priest and Sal Sama for this episode of The High Ground powered by Premier Companies.  Matt is the Vice President of Supply and Marketing for CountryMark, and he's got a lot to share regarding what's happened in the two years since he joined us last!You'll hear about the latest CountryMark news and their renewable diesel co-processing project which involves expanding the capacity in the refinery and adding the capability to process soybean oil.  In addition to sustainability, you'll learn about the other benefits of renewable diesel, what goes into creating the product, and how it's different from biodiesel.  In addition to learning about how this project will help increase the overall output, you'll learn how this project will help hedge against RFS compliance costs if RIN prices go up.  If you're wondering what the Renewable Identification Number system is all about and how it impacts growers in the first place, you'll learn about that and more!

What's all this hype around renewable diesel?  To help us dig into this topic, Matt Makinson comes back to join hosts Ryan Priest and Sal Sama for this episode of The High Ground powered by Premier Companies.  Matt is the Vice President of Supply and Marketing for CountryMark, and he's got a lot to share regarding what's happened in the two years since he joined us last!You'll hear about the latest CountryMark news and their renewable diesel co-processing project which involves expanding the capacity in the refinery and adding the capability to process soybean oil.  In addition to sustainability, you'll learn about the other benefits of renewable diesel, what goes into creating the product, and how it's different from biodiesel.  In addition to learning about how this project will help increase the overall output, you'll learn how this project will help hedge against RFS compliance costs if RIN prices go up.  If you're wondering what the Renewable Identification Number system is all about and how it impacts growers in the first place, you'll learn about that and more!

It's Regency drama, gossip, and scandalous dances on this week's Doctor Who adventure, “Rogue!” The Bridgerton fans are losing their minds at this episode, including one Ruby Sunday, but what did the Three Who Rule think of this theatrical and romantic undertaking? Plus we pay tribute to William Russell, Doctor Who's original Man of Action and Knight of Jaffa, and we encourage you to listen to our own interview with Mr. Russell from 2012. Plus Big Finish celebrates 25 years, Tales of the TARDIS mystery, and this very podcast gets called out for both its numerous crimes and its place as one of the best Doctor Who podcasts! Will wonders never cease? Links: Support Radio Free Skaro on Patreon Review: Doctor Who S1E06 “Rogue” Returning to the Regency William Russell, Doctor Who legend, dies aged 99 Carole Ann Ford's tribute to William Russell RFS 298 with William Russell interview A new Tales of the TARDIS episode airing on BBC Four on June 20 Radio Times: Ncuti Gatwa and Millie Gibson star in Tales of the TARDIS Big Finish: Doctor Who: The Sirens of Time – Redux due November 2024 Big Finish: Dark Gallifrey: The War Master starts in July Big FInish: Doctor Who – The Lost Stories: Deathworld due in July Next Time: S1E07 “The Legend of Ruby Sunday” June 15, 630pm on BBC One Radio Times lists RFS and The Memory Cheats as one of the best DW podcasts